Gene: NPPA

4878
ANF|ANP|ATFB6|ATRST2|CDD|CDD-ANF|CDP|PND
natriuretic peptide A
protein-coding
1p36.22
Ensembl:ENSG00000175206 MIM:108780 Vega:OTTHUMG00000002388 UniprotKB:P01160
NG_012926.1
PubMed
0   ANCO-SNPs
ND
3   
6.733e-1 (AD)  5.889e-1 (ND)   (Frontal_Cortex)
7.987e-1 (AD)  5.841e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg06193043chr1:11908199NPPA2.600e-13Smoking27651444
cg14194983chr1:11908298NPPA2.000e-10Smoking27651444
cg05396397chr1:11908164NPPA1.900e-9Smoking27651444

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MYH60.518
MYL70.513
MYL40.466
FAM173A0.436
CCDC85B0.435
BMP100.434
TPGS10.43
USE10.423
PLCH20.423
TXNL4A0.421

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
P2RY14-0.276
FCGR3B-0.273
CXCR2-0.267
OR4F29-0.259
CYSLTR2-0.257
EDN1-0.255
OR52E2-0.247
OR4F5-0.245
TM4SF18-0.244
GJA5-0.242

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5616191-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of NPPA mRNA]21383588
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D results in decreased expression of NPPA mRNA"15837528
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of NPPA mRNA"19162173
C0513601,3-dipropyl-8-cyclopentylxanthine"1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
C0513601,3-dipropyl-8-cyclopentylxanthine"1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"15452191
C02598415-hydroxy-5,8,11,13-eicosatetraenoic acid"15-hydroxy-5,8,11,13-eicosatetraenoic acid results in increased expression of NPPA mRNA"25600587
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]"15240149|1671403
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of NPPA mRNA"25614096
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]10727428
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased expression of NPPA protein]10727428
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of NPPA mRNA]19111554
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of NPPA protein10727428
C1202272-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide"2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]"12513686
C0011052,2'-dipyridyl disulfide"2,2'-dipyridyl disulfide results in increased expression of NPPA protein"25449040
C0011052,2'-dipyridyl disulfide"polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased expression of NPPA protein]"25449040
C5391422-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one"2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one results in increased susceptibility to NPPA protein"24899690
C4191462,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate"2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
C4191462,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate"2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"15452191
C0612822-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191|1996605
C0612822-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosineCaffeine analog inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]15452191
C1099862-aminoethoxydiphenyl borate2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16787574
C1099862-aminoethoxydiphenyl boratechelerythrine promotes the reaction [2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]16787574
C4867842-methyl-3-(4-(2-(5-methyl-2-thiophen-2-yloxazol-4-yl)ethoxy)phenyl)-2-phenoxypropionic acid2-methyl-3-(4-(2-(5-methyl-2-thiophen-2-yloxazol-4-yl)ethoxy)phenyl)-2-phenoxypropionic acid results in increased expression of NPPA mRNA20044590
C4867842-methyl-3-(4-(2-(5-methyl-2-thiophen-2-yloxazol-4-yl)ethoxy)phenyl)-2-phenoxypropionic acid2-methyl-3-(4-(2-(5-methyl-2-thiophen-2-yloxazol-4-yl)ethoxy)phenyl)-2-phenoxypropionic acid results in increased expression of NPPA protein20044590
C5201644-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15721863
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]25341891
C0017894-nitrobenzylthioinosine"1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
C0017894-nitrobenzylthioinosine"2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
C0017894-nitrobenzylthioinosine8-(3-chlorostyryl)caffeine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
C0017894-nitrobenzylthioinosine8-(4-sulfophenyl)theophylline inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
C0017894-nitrobenzylthioinosine[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966059
C0335024-trifluoromethylsalicylic acid4-trifluoromethylsalicylic acid inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]16421291
C0920067-Ala-angiotensin (1-7)7-Ala-angiotensin (1-7) inhibits the reaction [AGT protein modified form results in decreased expression of NPPA mRNA]20837116
C0920067-Ala-angiotensin (1-7)7-Ala-angiotensin (1-7) inhibits the reaction [AGT protein modified form results in decreased expression of NPPA protein]20837116
C0813208-(3-chlorostyryl)caffeine8-(3-chlorostyryl)caffeine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
C0556568-((4-chlorophenyl)thio)cyclic-3',5'-GMP"[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]"11799084
C0314338-(4-sulfophenyl)theophylline8-(4-sulfophenyl)theophylline inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
C0101929-(2-hydroxy-3-nonyl)adenine"1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
C0101929-(2-hydroxy-3-nonyl)adenine"2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
C0101929-(2-hydroxy-3-nonyl)adenine8-(3-chlorostyryl)caffeine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
C0101929-(2-hydroxy-3-nonyl)adenine8-(4-sulfophenyl)theophylline inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
C0101929-(2-hydroxy-3-nonyl)adenine[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966059
D019342Acetic AcidAcetic Acid results in decreased expression of NPPA protein21296659
C016957adenosine-3',5'-cyclic phosphorothioate"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]"18977371
D000242Cyclic AMP[8-Bromo Cyclic Adenosine Monophosphate results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein12714356
D000242Cyclic AMP"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]"18977371
D000242Cyclic AMPCimetidine inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
D000242Cyclic AMP[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein12714356
D000242Cyclic AMPHRH2 protein promotes the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]12714356
D000242Cyclic AMPKT 5720 inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
D000242Cyclic AMPStaurosporine inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
D000450AldosteroneNPPA protein results in decreased secretion of Aldosterone2434734|2931268
D000450AldosteroneAldosterone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966502
D000450AldosteroneAldosterone results in increased expression of NPPA mRNA19966502
D000450AldosteroneSpironolactone inhibits the reaction [Aldosterone results in increased expression of NPPA mRNA]19966502
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]"16534557
D000526AlprenololAlprenolol results in increased expression of NPPA mRNA12721106
D000638AmiodaroneAmiodarone results in increased expression of NPPA mRNA17535870
D017311AmlodipineAmlodipine results in decreased expression of NPPA mRNA17563544
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NPPA mRNA16483693
D000806Angiotensin-Converting Enzyme InhibitorsAngiotensin-Converting Enzyme Inhibitors results in decreased expression of NPPA protein1647690
D001127Arginine VasopressinNPPA protein results in decreased susceptibility to Arginine Vasopressin8188982
C026987aroclor 1260[Methionine deficiency co-treated with Choline deficiency co-treated with aroclor 1260] results in increased expression of NPPA mRNA28163111
D001151ArsenicArsenic results in increased expression of NPPA mRNA19654921
D001262AtenololAtenolol results in decreased expression of NPPA protein12866806
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]19136528
D001280AtrazineAtrazine results in decreased expression of NPPA mRNA22378314
D001285AtropineAtropine affects the activity of NPPA protein modified form1363893
D001374AzacitidineAzacitidine results in increased expression of NPPA15005238
C051019BAEC protocolBAEC protocol affects the expression of NPPA protein16856907
C044946benazeprilbenazepril results in decreased expression of NPPA mRNA11136700|8763405
C044946benazepril[Valsartan co-treated with benazepril] results in decreased expression of NPPA mRNA11136700
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of NPPA mRNA19969063
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of NPPA mRNA22228805
D001564Benzo(a)pyrene1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of NPPA mRNA]21383588
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NPPA mRNA19889059|2138358
D001564Benzo(a)pyreneN-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine inhibits the reaction [Benzo(a)pyrene results in increased expression of NPPA mRNA]19889059
D004958Estradiol[Progesterone co-treated with Estradiol] results in increased expression of NPPA mRNA18692832
D004958Estradiol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of NPPA mRNA]19111554
D004958EstradiolEstradiol results in increased expression of NPPA mRNA19111554
D004958EstradiolEstradiol results in increased expression of NPPA protein14718400
D004958Estradiolfulvestrant inhibits the reaction [[Estradiol co-treated with Phenylephrine] results in increased expression of NPPA protein]14718400
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased expression of NPPA mRNA]14718400
D015784BetaxololBetaxolol results in decreased expression of NPPA mRNA12693380
D015784BetaxololBetaxolol results in decreased expression of NPPA protein12693380
C088060bisindolylmaleimidebisindolylmaleimide inhibits the reaction [MBF1 protein results in increased secretion of NPPA protein]12729799
C006780bisphenol Abisphenol A affects the expression of NPPA mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of NPPA mRNA26063408
C006780bisphenol Abisphenol A results in increased expression of NPPA mRNA27809950
C006780bisphenol Abisphenol A results in decreased expression of NPPA mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of NPPA gene28505145
D001786Blood GlucoseNFE2L2 gene mutant form promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NPPA mRNA]28373008
D001786Blood Glucose[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NPPA mRNA28373008
C086539BQ 788BQ 788 inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]15007106
C086539BQ 788BQ 788 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15007106
D0151248-Bromo Cyclic Adenosine Monophosphate[8-Bromo Cyclic Adenosine Monophosphate results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein12714356
D0151248-Bromo Cyclic Adenosine MonophosphateKT 5720 inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
C099813bromochloroacetic acidbromochloroacetic acid results in increased expression of NPPA protein21296659
D002110CaffeineCaffeine analog inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]15452191
D002110CaffeineCaffeine results in increased expression of NPPA mRNA25093688
D002110CaffeineDantrolene inhibits the reaction [Caffeine results in increased expression of NPPA mRNA]25093688
C081643candesartancandesartan results in increased expression of NPPA mRNA14639023
C081643candesartancandesartan results in increased expression of NPPA protein14639023
C081643candesartancandesartan results in increased secretion of NPPA protein14639023
C060942candoxatrilatcandoxatrilat inhibits the reaction [Carbon Tetrachloride results in decreased secretion of NPPA protein]16449355
C071423capsazepinecapsazepine inhibits the reaction [NPPA protein results in increased secretion of CALCA protein]17522345
D002217CarbacholCarbachol results in increased secretion of NPPA protein8234284
D002248Carbon MonoxideCarbon Monoxide results in increased expression of NPPA mRNA11781074
D002251Carbon Tetrachloridecandoxatrilat inhibits the reaction [Carbon Tetrachloride results in decreased secretion of NPPA protein]16449355
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased secretion of NPPA protein16449355
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of NPPA mRNA16644059
C514968carboxymethyl-chitosancarboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of NPPA mRNA]26612707
C043211carvedilolcarvedilol results in decreased expression of NPPA protein1378157
C043211carvedilolcarvedilol inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]10722803
C043211carvedilolcarvedilol promotes the reaction [NPPA protein results in increased abundance of Cyclic GMP]9421401
C043211carvedilolcarvedilol results in decreased degradation of NPPA protein9421401
C043211carvedilolcarvedilol results in decreased expression of NPPA mRNA21216836
C043211carvedilolcarvedilol results in increased expression of NPPA mRNA11206715
C043211carvedilolcarvedilol results in increased expression of NPPA protein11206715|9421401
C469298CEP-11004CEP-11004 inhibits the reaction [Phenylephrine results in increased secretion of NPPA protein]20067472
C469298CEP-11004CEP-11004 inhibits the reaction [EDN1 protein results in increased secretion of NPPA protein]20067472
C511403CGS 35601CGS 35601 affects the expression of NPPA protein16364833
C016299chelerythrinechelerythrine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16787574
C016299chelerythrinechelerythrine promotes the reaction [2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]16787574
D002712ChloridesCytochalasin D inhibits the reaction [NPPA protein results in increased secretion of Chlorides]12444471
D002712ChloridesCytochalasin D promotes the reaction [Procaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]]12444471
D002712ChloridesML 7 inhibits the reaction [NPPA protein results in increased secretion of Chlorides]12444471
D002712ChloridesML 7 promotes the reaction [Procaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]]12444471
D002712ChloridesNPPA protein results in increased secretion of Chlorides12444471
D002712ChloridesProcaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]12444471
D0157622-Chloroadenosine2-Chloroadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with aroclor 1260] results in increased expression of NPPA mRNA28163111
C034587CHOP protocolCHOP protocol results in increased expression of NPPA protein16247790
D017315CilazaprilCilazapril affects the secretion of NPPA protein1457087
D017315Cilazapril[Cilazapril co-treated with Verapamil] affects the secretion of NPPA protein1457087
D002927CimetidineCimetidine inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
C014282cirazolineADRA1A protein promotes the reaction [cirazoline results in increased expression of NPPA protein]18378355
C014282cirazolinecirazoline results in increased expression of NPPA protein18378355
D002994ClofibrateClofibrate results in decreased expression of NPPA mRNA17585979
D003000ClonidineClonidine results in increased expression of NPPA protein18378355
C018021cobaltous chloridecobaltous chloride results in increased expression of NPPA mRNA11078357|1107837
D003042CocaineCocaine results in increased expression of NPPA protein11377647
D003042CocaineCocaine results in increased expression of NPPA mRNA9455993
D005576ColforsinColforsin inhibits the reaction [Dinoprostone results in increased expression of NPPA protein]18851973
D005576ColforsinColforsin inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11470465|1885197
D019327Copper SulfateCopper Sulfate results in decreased expression of NPPA mRNA19549813
D003345CorticosteroneCorticosterone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]16533503
D003345CorticosteroneCorticosterone results in increased expression of NPPA mRNA16533503
C038106cucurbitacin Icucurbitacin I results in increased expression of NPPA mRNA27836799
D003471CuprizoneCuprizone results in decreased expression of NPPA mRNA26577399
D003474Curcumincarboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of NPPA mRNA]26612707
D003474CurcuminCurcumin results in decreased expression of NPPA mRNA26612707
D003484Cyanamide[Ethanol co-treated with Cyanamide] results in increased expression of NPPA mRNA10905996
D003520CyclophosphamideCyclophosphamide results in increased expression of NPPA protein2950859
D016572CyclosporineCyclosporine affects the expression of NPPA mRNA19244478
D016572CyclosporineCyclosporine inhibits the reaction [IGF1 protein results in increased expression of NPPA mRNA]11548882
C072247cyclo(Trp-Asp-Pro-Val-Leu)cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [AGT protein results in increased expression of NPPA protein]15007106
C072247cyclo(Trp-Asp-Pro-Val-Leu)cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15007106
D015638Cytochalasin DCytochalasin D inhibits the reaction [NPPA protein results in increased secretion of Chlorides]12444471
D015638Cytochalasin DCytochalasin D promotes the reaction [Procaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]]12444471
D003620DantroleneDantrolene inhibits the reaction [Caffeine results in increased expression of NPPA mRNA]25093688
D003630DaunorubicinDaunorubicin results in increased expression of NPPA mRNA27816693
D003630DaunorubicinDaunorubicin results in increased expression of NPPA mRNA26328012|2709088
D003907DexamethasoneDexamethasone results in increased expression of NPPA protein1934541
D003907Dexamethasone[Dexamethasone co-treated with Doxorubicin] results in increased expression of NPPA mRNA19596060
D003907DexamethasoneMifepristone inhibits the reaction [[Dexamethasone co-treated with Doxorubicin] results in increased expression of NPPA mRNA]19596060
D003907DexamethasoneDexamethasone inhibits the reaction [nitrofen results in decreased expression of NPPA mRNA]11584395
D003907DexamethasoneDexamethasone inhibits the reaction [nitrofen results in decreased expression of NPPA protein]11584395
D003907DexamethasoneDexamethasone results in decreased expression of NPPA protein2965178
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NPPA mRNA21266533
D019259Lamivudine[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA11706060
D004041Dietary FatsDietary Fats results in increased expression of NPPA mRNA25016146
D019422Dietary Sucrose"Dietary Sucrose promotes the reaction [Sodium, Dietary results in increased expression of NPPA mRNA]"18551017
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of NPPA protein15283993
D004077DigoxinDigoxin results in increased expression of NPPA mRNA19687166
D004077Digoxin"N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Digoxin results in increased expression of NPPA mRNA]"19687166
D004281Docosahexaenoic AcidsDocosahexaenoic Acids inhibits the reaction [Phenylephrine affects the expression of NPPA protein]15258898
C012301domoic aciddomoic acid results in increased expression of NPPA mRNA25691335
D004317DoxorubicinDoxorubicin results in increased expression of NPPA protein11466716|1172464
D004317DoxorubicinCDKN1A gene mutant form inhibits the reaction [Doxorubicin results in increased expression of NPPA mRNA]21920376
D004317Doxorubicin[Dexamethasone co-treated with Doxorubicin] results in increased expression of NPPA mRNA19596060
D004317DoxorubicinDoxorubicin results in decreased expression of NPPA mRNA17531194
D004317DoxorubicinDoxorubicin results in increased expression of NPPA mRNA10618415|2192037
D004317DoxorubicinDoxorubicin results in increased expression of NPPA protein23695218
D004317DoxorubicinFenofibrate inhibits the reaction [Doxorubicin results in decreased expression of NPPA mRNA]17531194
D004317DoxorubicinLovastatin inhibits the reaction [Doxorubicin results in increased expression of NPPA mRNA]28710503
D004317DoxorubicinMifepristone inhibits the reaction [[Dexamethasone co-treated with Doxorubicin] results in increased expression of NPPA mRNA]19596060
D004317DoxorubicinNSC 23766 inhibits the reaction [Doxorubicin results in increased expression of NPPA mRNA]28710503
D004317Doxorubicinresveratrol inhibits the reaction [Doxorubicin results in increased expression of NPPA protein]23695218
D004317DoxorubicinSTAT3 protein promotes the reaction [Doxorubicin results in increased expression of NPPA mRNA]10618415
D004317DoxorubicinDoxorubicin affects the expression of NPPA protein1533234
D004317DoxorubicinDoxorubicin results in decreased activity of NPPA protein8318687
D004317DoxorubicinDoxorubicin results in decreased expression of NPPA mRNA19796650
D004317DoxorubicinDoxorubicin results in increased expression of NPPA mRNA16766856
D004317DoxorubicinNPPA protein promotes the reaction [Doxorubicin results in increased expression of PPIB mRNA]8318687
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of NPPA protein]"16409969
C062597efaroxanefaroxan inhibits the reaction [Naphazoline results in increased secretion of NPPA protein]12037379
D004656EnalaprilEnalapril results in decreased expression of NPPA protein12019275
D004656EnalaprilFR 173657 inhibits the reaction [Enalapril results in decreased expression of NPPA protein]12019275
D004656EnalaprilEnalapril results in decreased expression of NPPA protein8112904
D004656EnalaprilEnalapril results in decreased expression of NPPA mRNA2136812|21423293
D015773EnalaprilatEnalaprilat inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]24342267
D015251EpirubicinEpirubicin results in increased expression of NPPA protein1831809
D004837EpinephrineNPPA protein affects the abundance of Epinephrine2951327
D000431Ethanol[Ethanol co-treated with Cyanamide] results in increased expression of NPPA mRNA10905996
D000431EthanolEthanol results in increased expression of NPPA mRNA11181050
C049347fasudilfasudil results in decreased expression of NPPA mRNA22465603
D015736FelodipineFelodipine affects the expression of NPPA protein9264493
D011345FenofibrateFenofibrate inhibits the reaction [Doxorubicin results in decreased expression of NPPA mRNA]17531194
D005472FluorouracilFluorouracil results in increased expression of NPPA protein21296659
C105311FR 173657FR 173657 inhibits the reaction [Enalapril results in decreased expression of NPPA protein]12019275
C069837fullerene C60fullerene C60 results in decreased expression of NPPA mRNA19167457
C070081fulvestrantfulvestrant inhibits the reaction [[Estradiol co-treated with Phenylephrine] results in increased expression of NPPA protein]14718400
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased expression of NPPA mRNA]14718400
D005665FurosemideFurosemide results in decreased expression of NPPA protein2146706
D005839GentamicinsGentamicins results in increased expression of NPPA mRNA17312373
D005947GlucoseGlucose results in increased expression of NPPA mRNA24810525
D005947GlucoseHMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]24810525
D005947GlucoseNPPA protein inhibits the reaction [SLC5A2 protein results in increased uptake of Glucose]15127950
D005947GlucosePropofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]24810525
D005947GlucoseSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]24810525
D005990GlycerolGlycerol results in increased expression of NPPA protein2177369
D006108GraphiteGraphite results in increased expression of NPPA mRNA27440207
D006143GuanabenzGuanabenz results in increased expression of NPPA protein18378355
D006152Cyclic GMPCyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K1 protein]18225537
D006152Cyclic GMPCyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K2 protein]18225537
D006152Cyclic GMPNPPA protein results in increased abundance of Cyclic GMP12582005
D006152Cyclic GMPAGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]11696475
D006152Cyclic GMPcarvedilol promotes the reaction [NPPA protein results in increased abundance of Cyclic GMP]9421401
D006152Cyclic GMPNPPA protein results in increased abundance of Cyclic GMP11696475|1202275
D006152Cyclic GMPPuromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]12972712
D006152Cyclic GMPvinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]11696475
D006152Cyclic GMPNPPA protein results in increased secretion of Cyclic GMP9874809
D006152Cyclic GMPOXT protein promotes the reaction [NPPA protein results in increased secretion of Cyclic GMP]9874809
C425931GW 501516[GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18701451
C529376GYY 4137GYY 4137 inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]28503736
C529376GYY 4137SIRT3 protein affects the reaction [GYY 4137 inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]]28503736
D006220HaloperidolHaloperidol affects the activity of NPPA protein modified form1363893
D01937712-Hydroxy-5,8,10,14-eicosatetraenoic Acid"12-Hydroxy-5,8,10,14-eicosatetraenoic Acid results in increased expression of NPPA mRNA"25600587
D006632Histamine"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]"18977371
D006632HistamineCimetidine inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
D006632Histamine[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein12714356
D006632HistamineHRH2 protein promotes the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]12714356
D006632HistamineStaurosporine inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
C072551HS 142-1HS 142-1 promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]10642269
C072551HS 142-1HS 142-1 promotes the reaction [Phenylephrine results in increased secretion of NPPA protein]10642269
C072551HS 142-1HS 142-1 results in increased expression of NPPA mRNA10642269
C072551HS 142-1HS 142-1 results in increased secretion of NPPA protein10642269
D006854HydrocortisoneHydrocortisone results in increased expression of NPPA protein7473517
D006854HydrocortisoneNPPA protein results in decreased secretion of Hydrocortisone2434734|2931268
D006861Hydrogen PeroxideNPPA protein results in decreased susceptibility to Hydrogen Peroxide10330004
D003900DesoxycorticosteroneDesoxycorticosterone results in increased expression of NPPA protein2965178
D007200IndicanIndican results in increased expression of NPPA mRNA25703824
D019469Indinavir[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA11706060
D007213IndomethacinIndomethacin results in decreased expression of NPPA protein1421905
D007213IndomethacinIndomethacin inhibits the reaction [NPPA protein affects the activity of MPO protein]17522345
D007213IndomethacinIndomethacin inhibits the reaction [NPPA protein affects the expression of TNF protein]17522345
C081309irbesartanirbesartan results in increased expression of NPPA protein12035877
D007545IsoproterenolIsoproterenol results in increased expression of NPPA protein19371759
D007545IsoproterenolEGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]10710348
D007545IsoproterenolIsoproterenol results in increased expression of NPPA mRNA11299230|1180499
D007545IsoproterenolNOS3 inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]12224825
D007545Isoproterenol[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA10710348
D007545IsoproterenolADRB1 protein promotes the reaction [Isoproterenol results in decreased expression of NPPA protein]18378355
D007545IsoproterenolAtorvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]19136528
D007545IsoproterenolCREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]12791704
D007545IsoproterenolIsoproterenol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18851973
D007545IsoproterenolIsoproterenol results in decreased expression of NPPA protein18378355
D007545IsoproterenolIsoproterenol results in increased expression of NPPA mRNA10888249|1099772
D007545Isoproterenolmanidipine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]9559417
D007545IsoproterenolMAP2K1 protein affects the reaction [Isoproterenol results in increased expression of NPPA mRNA]10888249
D007545IsoproterenolPropranolol inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]10997724
D007545IsoproterenolSirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]25045214
D007545IsoproterenolSpironolactone inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]23288202
D007545IsoproterenolTNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]25045214
D007545IsoproterenolValsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]23288202
C544151jinfukangjinfukang results in increased expression of NPPA mRNA27392435
C098607JP8 aviation fuelJP8 aviation fuel results in decreased expression of NPPA mRNA15618438
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]23939492
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]23939492
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA protein]23939492
C119620kenpaullonekenpaullone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]25341891
C063302KN 62KN 62 inhibits the reaction [LIF protein results in increased expression of NPPA protein]11073891
C057416KT 5720KT 5720 inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
C057416KT 5720KT 5720 inhibits the reaction [NPPA protein results in increased secretion of CALCA protein]17522345
D007741LabetalolLabetalol results in decreased activity of NPPA protein2524958
C038753leptomycin Bleptomycin B inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]25341891
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of NPPA mRNA18701451
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of NPPA protein22224641
D008070LipopolysaccharidesNPPA protein inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]12022755
D017706LisinoprilLisinopril results in decreased expression of NPPA protein8393685
D019808LosartanLosartan inhibits the reaction [Nitric Oxide deficiency results in increased expression of NPPA mRNA]12198334
D019808LosartanLosartan results in decreased expression of NPPA protein12198334
D008148LovastatinLovastatin inhibits the reaction [Doxorubicin results in increased expression of NPPA mRNA]28710503
C032881lysophosphatidic acidlysophosphatidic acid results in increased expression of NPPA protein25449040
C032881lysophosphatidic acidPertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]15081308
C032881lysophosphatidic acidY 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]25449040
D008345ManganeseManganese results in decreased expression of NPPA mRNA17175027
C025340manganese chloridemanganese chloride results in decreased expression of NPPA mRNA17175027
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]25449040
C054218manidipinemanidipine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]9559417
D008353MannitolMannitol results in increased expression of NPPA protein2177369
D008627Mercuric ChlorideMercuric Chloride results in increased expression of NPPA mRNA24472606
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with aroclor 1260] results in increased expression of NPPA mRNA28163111
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased secretion of NPPA protein"21827841
D008790MetoprololMetoprolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]17592507
D008790MetoprololMetoprolol results in decreased expression of NPPA mRNA20353484
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]]16534557
D015735MifepristoneMifepristone inhibits the reaction [[Dexamethasone co-treated with Doxorubicin] results in increased expression of NPPA mRNA]19596060
D015735MifepristoneMifepristone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA]16533503
C070571ML 7ML 7 inhibits the reaction [NPPA protein results in increased secretion of Chlorides]12444471
C070571ML 7ML 7 promotes the reaction [Procaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]]12444471
D016686MonocrotalineMonocrotaline results in increased expression of NPPA mRNA16936438
C043482moxonidinemoxonidine results in increased secretion of NPPA protein12037379
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]18851973
C481648N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine"N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Digoxin results in increased expression of NPPA mRNA]"19687166
C481648N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine"N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Ouabain results in increased expression of NPPA mRNA]"19687166
C481648N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine"N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]"16513848
C477659N-(3-methoxyphenyl)-4-chlorocinnamanilideN-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [NPPA protein affects the activity of MPO protein]17522345
C477659N-(3-methoxyphenyl)-4-chlorocinnamanilideN-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [NPPA protein affects the expression of CALCA protein]17522345
C477659N-(3-methoxyphenyl)-4-chlorocinnamanilideN-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [NPPA protein affects the expression of TNF protein]17522345
C084956N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine"2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"15452191
C084956N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosineN(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191|1996605
C048599N(6)-cyclopentyladenosine"1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"15452191
C048599N(6)-cyclopentyladenosineN(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191|1996605
C483758N(6)-phenyl-cAMPN(6)-phenyl-cAMP analog inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18851973
D009270NaloxoneNaloxone results in decreased expression of NPPA protein11311734
D009278Naphazolineefaroxan inhibits the reaction [Naphazoline results in increased secretion of NPPA protein]12037379
D009278Naphazoline[Naphazoline affects the activity of NISCH protein] which results in increased secretion of NPPA protein12037379
D009278NaphazolineNaphazoline results in increased secretion of NPPA protein12037379
C433446N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidineN-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine inhibits the reaction [Benzo(a)pyrene results in increased expression of NPPA mRNA]19889059
D009543NifedipineNifedipine results in decreased expression of NPPA mRNA20559781
D009569Nitric OxideLosartan inhibits the reaction [Nitric Oxide deficiency results in increased expression of NPPA mRNA]12198334
D009569Nitric OxideNitric Oxide deficiency results in increased expression of NPPA mRNA10397678|1219833
D009569Nitric OxideNitric Oxide deficiency results in increased expression of NPPA protein14700747|1517793
C007350nitrofenDexamethasone inhibits the reaction [nitrofen results in decreased expression of NPPA mRNA]11584395
C007350nitrofenDexamethasone inhibits the reaction [nitrofen results in decreased expression of NPPA protein]11584395
C007350nitrofennitrofen results in decreased expression of NPPA mRNA11584395
C007350nitrofennitrofen results in decreased expression of NPPA protein11584395
D026423S-Nitroso-N-Acetylpenicillamine[S-Nitroso-N-Acetylpenicillamine co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11799084
D009638NorepinephrineNorepinephrine results in increased expression of NPPA protein8952593
D009638NorepinephrineNorepinephrine results in increased expression of NPPA mRNA9788975
D009638Norepinephrine"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]"15240149|1671403
D009638Norepinephrinecarvedilol inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]10722803
D009638NorepinephrineNorepinephrine results in increased expression of NPPA mRNA10722803|1457759
D009638NorepinephrinePrazosin inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]15240149|1671403
D009638NorepinephrinePropranolol promotes the reaction [Norepinephrine results in increased expression of NPPA mRNA]17592507
D009638NorepinephrineNorepinephrine results in increased secretion of NPPA protein8234284
C487513NSC 23766NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of NPPA mRNA]28710503
C106266omapatrilatomapatrilat results in increased expression of NPPA protein11762555
D010100OxygenNFE2L2 gene mutant form promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NPPA mRNA]28373008
D010100Oxygen[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NPPA mRNA28373008
D010100Oxygen[Phenylephrine co-treated with Oxygen deficiency] results in increased expression of NPPA mRNA11042672
C084656paricalcitolparicalcitol inhibits the reaction [EDN1 protein results in increased expression of NPPA mRNA]21565836
C084656paricalcitolparicalcitol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]21565836
D010424PentobarbitalPentobarbital results in decreased expression of NPPA protein8464334
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]15081308
D015232DinoprostoneColforsin inhibits the reaction [Dinoprostone results in increased expression of NPPA protein]18851973
D015232DinoprostoneDinoprostone results in increased expression of NPPA mRNA18030065
D015232DinoprostoneDinoprostone results in increased expression of NPPA protein18851973
D015232DinoprostoneNPPA protein results in increased abundance of Dinoprostone3070145
D010656PhenylephrinePhenylephrine results in increased secretion of NPPA protein2847676
D010656PhenylephrineANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18502941
D010656PhenylephrineDGKZ protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16380548
D010656PhenylephrineEGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]10710348
D010656PhenylephrineHEY2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16603706
D010656PhenylephrineJUND protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16690042
D010656PhenylephrineMOV10L1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]12754203
D010656Phenylephrine[NPPA protein results in increased activity of NPR1 protein] promotes the reaction [Phenylephrine results in increased localization of NFATC3 protein]15939815
D010656Phenylephrine[Phenylephrine co-treated with ADRA1B protein] results in increased expression of NPPA protein11499749
D010656Phenylephrine[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA10710348
D010656Phenylephrine[Phenylephrine results in increased activity of ITPR2 protein] which results in increased expression of NPPA mRNA15201137
D010656PhenylephrinePhenylephrine results in increased expression of NPPA mRNA11299230|1180499
D010656PhenylephrinePhenylephrine results in increased expression of NPPA protein10679475
D010656Phenylephrine"1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
D010656Phenylephrine"1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"15452191
D010656Phenylephrine"2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]"12513686
D010656Phenylephrine"2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"19966059
D010656Phenylephrine"2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]"15452191
D010656Phenylephrine2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191|1996605
D010656Phenylephrine2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16787574
D010656Phenylephrine2-Chloroadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191
D010656Phenylephrine4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15721863
D010656Phenylephrine4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]25341891
D010656Phenylephrine4-trifluoromethylsalicylic acid inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]16421291
D010656Phenylephrine8-(3-chlorostyryl)caffeine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
D010656Phenylephrine"[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]"11799084
D010656Phenylephrine8-(4-sulfophenyl)theophylline inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]19966059
D010656Phenylephrine[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966059
D010656PhenylephrineADM protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11470465
D010656PhenylephrineADORA1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966059
D010656PhenylephrineADORA2A protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966059
D010656PhenylephrineADORA3 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966059
D010656PhenylephrineAldosterone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966502
D010656PhenylephrineBQ 788 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15007106
D010656PhenylephrineCABIN1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]10655507
D010656PhenylephrineCABIN1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]10655507
D010656PhenylephrineCaffeine analog inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]15452191
D010656PhenylephrineCEP-11004 inhibits the reaction [Phenylephrine results in increased secretion of NPPA protein]20067472
D010656Phenylephrinechelerythrine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16787574
D010656Phenylephrinechelerythrine promotes the reaction [2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]16787574
D010656PhenylephrineColforsin inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11470465|1885197
D010656PhenylephrineCorticosterone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]16533503
D010656PhenylephrineCREBBP protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]11705990
D010656Phenylephrinecyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15007106
D010656PhenylephrineDocosahexaenoic Acids inhibits the reaction [Phenylephrine affects the expression of NPPA protein]15258898
D010656PhenylephrineEP300 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]11705990|2709436
D010656PhenylephrineEYA2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]17327491
D010656Phenylephrinefulvestrant inhibits the reaction [[Estradiol co-treated with Phenylephrine] results in increased expression of NPPA protein]14718400
D010656PhenylephrineGLRX3 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]16809552
D010656PhenylephrineGRK2 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]28759639
D010656Phenylephrine[GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18701451
D010656PhenylephrineHS 142-1 promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]10642269
D010656PhenylephrineHS 142-1 promotes the reaction [Phenylephrine results in increased secretion of NPPA protein]10642269
D010656PhenylephrineIKBKB protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]11381115
D010656PhenylephrineILK protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]16170337
D010656PhenylephrineIsoproterenol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18851973
D010656Phenylephrine(+)-JQ1 compound inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]23939492
D010656Phenylephrine(+)-JQ1 compound inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]23939492
D010656PhenylephrineJUN gene mutant form inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11799083
D010656PhenylephrineKCND2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]12403671
D010656Phenylephrinekenpaullone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]25341891
D010656Phenylephrineleptomycin B inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]25341891
D010656Phenylephrinemanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]25449040
D010656PhenylephrineMAP2K1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]10888249
D010656PhenylephrineMAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11513749
D010656PhenylephrineMBF1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]12729799
D010656PhenylephrineMEKK1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]10727428
D010656PhenylephrineMetoprolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]17592507
D010656PhenylephrineMOV10L1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11854500
D010656PhenylephrineMYOCD protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]14676212
D010656PhenylephrineN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]18851973
D010656Phenylephrine"N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]"16513848
D010656PhenylephrineN(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191|1996605
D010656PhenylephrineN(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15452191|1996605
D010656PhenylephrineN(6)-phenyl-cAMP analog inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18851973
D010656PhenylephrineNFKBIA protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]11381115
D010656PhenylephrineNPPA protein results in decreased susceptibility to Phenylephrine8188982
D010656PhenylephrineOuabain promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]17266992
D010656Phenylephrineparicalcitol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]21565836
D010656PhenylephrinePDE5A protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]18790048
D010656Phenylephrine[Phenylephrine co-treated with Oxygen deficiency] results in increased expression of NPPA mRNA11042672
D010656PhenylephrinePhenylephrine inhibits the reaction [KLF4 protein binds to NPPA promoter]19729022
D010656PhenylephrinePhenylephrine promotes the reaction [BRD4 protein binds to NPPA promoter]23939492
D010656PhenylephrinePhenylephrine promotes the reaction [CTNNB1 protein binds to NPPA promoter]19799869
D010656PhenylephrinePhenylephrine promotes the reaction [EP300 protein binds to NPPA promoter]23297412
D010656PhenylephrinePhenylephrine promotes the reaction [MYOCD protein binds to NPPA promoter]16556869
D010656Phenylephrine[Phenylephrine results in increased activity of CREBBP protein] which results in increased expression of NPPA protein12477714
D010656Phenylephrine[Phenylephrine results in increased activity of EP300 protein] which results in increased expression of NPPA protein12477714
D010656PhenylephrinePhenylephrine results in increased expression of NPPA mRNA10642269|1065550
D010656PhenylephrinePhenylephrine results in increased expression of NPPA protein10655507|1072742
D010656PhenylephrinePhenylephrine results in increased secretion of NPPA protein10642269|1175497
D010656Phenylephrine[pirinixic acid binds to PPARA protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18701451
D010656Phenylephrinepolydatin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]25449040
D010656PhenylephrinePrazosin inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]17592507
D010656PhenylephrinePrazosin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]12513686
D010656PhenylephrinePRKCZ protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]27094369
D010656PhenylephrinePropranolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]17592507
D010656Phenylephrineresveratrol inhibits the reaction [Phenylephrine promotes the reaction [EP300 protein binds to NPPA promoter]]23297412
D010656Phenylephrineresveratrol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]23297412
D010656PhenylephrineRGS2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16517124
D010656PhenylephrineRHOA protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]10843871
D010656PhenylephrineSB 203580 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]10727428
D010656PhenylephrineSildenafil Citrate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18790048
D010656Phenylephrine[SIRT6 protein co-treated with EP300 protein] affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]27094368
D010656PhenylephrineSIRT6 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]27094368
D010656PhenylephrineSK-7041 inhibits the reaction [Phenylephrine inhibits the reaction [KLF4 protein binds to NPPA promoter]]19729022
D010656PhenylephrineSK-7041 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19729022
D010656Phenylephrine[S-Nitroso-N-Acetylpenicillamine co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11799084
D010656PhenylephrineSpironolactone inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966502
D010656PhenylephrineTGFB1I1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]19540241
D010656PhenylephrineTGFB1I1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]19540241
D010656Phenylephrinetrichostatin A inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19729022|2534189
D010656Phenylephrinetriflusal inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]16421291
D010656Phenylephrinetyrphostin AG 1478 inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]14676212
D010656PhenylephrineU 0126 inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]12513686
D010656PhenylephrineUridine Triphosphate inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]14676212
D010656PhenylephrineUridine Triphosphate inhibits the reaction [MYL2 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]14676212
D010656PhenylephrineUridine Triphosphate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]14676212
D010656Phenylephrinexestospongin C inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16787574
D010656PhenylephrineY 27632 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11739382
D010656PhenylephrineY 27632 inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]25449040
D010656PhenylephrineZFPM2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]15220332
C005435phenylmethylpyrazolonephenylmethylpyrazolone results in decreased expression of NPPA mRNA15824197
C006253pirinixic acidpirinixic acid results in increased expression of NPPA mRNA17951219|2081375
C006253pirinixic acid[pirinixic acid binds to PPARA protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18701451
D010936Plant ExtractsPlant Extracts results in decreased expression of NPPA mRNA23557933
D010936Plant ExtractsPlant Extracts affects the expression of NPPA mRNA17645561
C058229polydatin"polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased expression of NPPA protein]"25449040
C058229polydatinpolydatin inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]25488910
C058229polydatinpolydatin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]25449040
D011224PrazosinPrazosin inhibits the reaction [EDN1 protein results in increased expression of NPPA protein]12513686
D011224PrazosinPrazosin inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]15240149|1671403
D011224PrazosinPrazosin inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]17592507
D011224PrazosinPrazosin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]12513686
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of NPPA mRNA22698814
D011343ProcaineCytochalasin D promotes the reaction [Procaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]]12444471
D011343ProcaineML 7 promotes the reaction [Procaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]]12444471
D011343ProcaineProcaine inhibits the reaction [NPPA protein results in increased secretion of Chlorides]12444471
D011374Progesterone[Progesterone co-treated with Estradiol] results in increased expression of NPPA mRNA18692832
D011374ProgesteroneProgesterone results in increased expression of NPPA mRNA18692832
D011374ProgesteroneProgesterone results in decreased expression of NPPA mRNA19690047
D011374ProgesteroneProgesterone results in increased expression of NPPA mRNA20726854
D015742PropofolHMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]24810525
D015742PropofolPropofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]24810525
D015742PropofolSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]24810525
D011433PropranololPropranolol results in increased expression of NPPA protein2566282
D011433PropranololPropranolol affects the activity of NPPA protein modified form1363893
D011433PropranololPropranolol inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]10997724
D011433PropranololPropranolol promotes the reaction [Norepinephrine results in increased expression of NPPA mRNA]17592507
D011433PropranololPropranolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]17592507
D011433PropranololPropranolol results in increased expression of NPPA mRNA17592507
D000527AlprostadilAlprostadil results in decreased expression of NPPA protein10506854
D011692Puromycin AminonucleosidePuromycin Aminonucleoside affects the expression of NPPA protein20613715
D011692Puromycin AminonucleosidePuromycin Aminonucleoside affects the metabolism of NPPA protein20613715
D011692Puromycin AminonucleosidePuromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]12972712
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of NPPA mRNA19885019|2061371
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of NPPA protein15590761|1988501
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased susceptibility to NPPA protein2526952
D011794QuercetinPPARG protein affects the reaction [Quercetin inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]]24039778
D011794QuercetinQuercetin inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]24039778
C041125quinaprilquinapril results in increased expression of NPPA mRNA14639023
C041125quinaprilquinapril results in increased expression of NPPA protein14639023
C041125quinaprilquinapril results in increased secretion of NPPA protein14639023
C059514resveratrolresveratrol results in decreased expression of NPPA mRNA23224687
C059514resveratrolresveratrol inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]25394677
C059514resveratrolresveratrol inhibits the reaction [DMD gene mutant form results in increased expression of NPPA mRNA]23297412
C059514resveratrolresveratrol inhibits the reaction [Doxorubicin results in increased expression of NPPA protein]23695218
C059514resveratrolresveratrol results in decreased expression of NPPA mRNA25394648
C059514resveratrolresveratrol affects the expression of NPPA mRNA17875610
C059514resveratrolresveratrol inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]18543488|2695573
C059514resveratrolresveratrol inhibits the reaction [AGT protein results in increased expression of NPPA protein]18543488
C059514resveratrolresveratrol inhibits the reaction [Phenylephrine promotes the reaction [EP300 protein binds to NPPA promoter]]23297412
C059514resveratrolresveratrol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]23297412
C059514resveratrolresveratrol inhibits the reaction [sunitinib results in increased expression of NPPA mRNA]24247421
C059514resveratrolresveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NPPA mRNA]19969063
C059514resveratrolresveratrol results in decreased expression of NPPA mRNA17499237|2539467
C059514resveratrolresveratrol results in decreased secretion of NPPA protein17499237
C089730rosiglitazonerosiglitazone results in increased expression of NPPA mRNA19397913|2117241
C089730rosiglitazonerosiglitazone results in increased expression of NPPA protein28822817
C089730rosiglitazoneSirolimus inhibits the reaction [rosiglitazone results in increased expression of NPPA mRNA]19397913
C111998sampatrilatsampatrilat results in increased susceptibility to NPPA protein12649357
C093642SB 203580SB 203580 affects the secretion of NPPA protein21084678
C093642SB 203580SB 203580 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]10727428
C093642SB 203580SB 203580 promotes the reaction [sunitinib results in increased expression of NPPA mRNA]24247421
C009250sevofluranesevoflurane results in decreased expression of NPPA mRNA26206149
D000068677Sildenafil CitrateSildenafil Citrate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]18790048
C076731simendansimendan inhibits the reaction [Sodium Chloride results in increased expression of NPPA mRNA]17325658
C076731simendansimendan results in decreased expression of NPPA mRNA20811386
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]]16534557
D019821SimvastatinSimvastatin inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]16534557
D019821SimvastatinSimvastatin results in decreased expression of NPPA mRNA16029635|1653455
D020123SirolimusSirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]25045214
D020123SirolimusSirolimus inhibits the reaction [rosiglitazone results in increased expression of NPPA mRNA]19397913
D020123SirolimusTNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]25045214
C497103SK-7041KLF4 protein affects the reaction [SK-7041 affects the expression of NPPA mRNA]19729022
C497103SK-7041SK-7041 affects the expression of NPPA mRNA19729022
C497103SK-7041SK-7041 inhibits the reaction [Phenylephrine inhibits the reaction [KLF4 protein binds to NPPA promoter]]19729022
C497103SK-7041SK-7041 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19729022
C025451sodium bisulfideSIRT3 protein affects the reaction [sodium bisulfide inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]]28503736
C025451sodium bisulfideSIRT3 protein affects the reaction [sodium bisulfide inhibits the reaction [AGT protein results in increased expression of NPPA protein]]28503736
C025451sodium bisulfidesodium bisulfide inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]28503736
C025451sodium bisulfidesodium bisulfide inhibits the reaction [AGT protein results in increased expression of NPPA protein]28503736
D012965Sodium Chloridesimendan inhibits the reaction [Sodium Chloride results in increased expression of NPPA mRNA]17325658
D012965Sodium ChlorideSodium Chloride results in increased expression of NPPA mRNA17325658
D017673Sodium Chloride, Dietary"NPPA protein affects the susceptibility to Sodium Chloride, Dietary"7839143
D017673Sodium Chloride, Dietary"Sodium Chloride, Dietary results in increased expression of NPPA protein"15177930
D012982Sodium, Dietary"Dietary Sucrose promotes the reaction [Sodium, Dietary results in increased expression of NPPA mRNA]"18551017
D012982Sodium, Dietary"Sodium, Dietary results in increased expression of NPPA mRNA"18551017
D013096SpermineSpermine results in increased expression of NPPA protein18673383
D013148SpironolactoneSpironolactone results in decreased expression of NPPA protein11300427
D013148SpironolactoneSpironolactone results in decreased expression of NPPA protein modified form9595286
D013148SpironolactoneSpironolactone inhibits the reaction [Aldosterone results in increased expression of NPPA mRNA]19966502
D013148SpironolactoneSpironolactone inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]23288202
D013148SpironolactoneSpironolactone inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19966502
D019311StaurosporineStaurosporine inhibits the reaction [[Histamine results in increased abundance of Cyclic AMP] which results in decreased expression of NPPA protein]18977371
D019311StaurosporineStaurosporine inhibits the reaction [MBF1 protein results in increased secretion of NPPA protein]12729799
D013311StreptozocinSLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA]18945756
D013311StreptozocinStreptozocin results in increased expression of NPPA mRNA18945756
D013311Streptozocin"Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of NPPA protein]"16409969
D013311StreptozocinStreptozocin results in increased expression of NPPA mRNA16980342
D013311StreptozocinStreptozocin results in increased expression of NPPA protein16409969
D010042Ouabain"N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Ouabain results in increased expression of NPPA mRNA]"19687166
D010042OuabainOuabain promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]17266992
D010042OuabainOuabain results in increased expression of NPPA mRNA19687166
C473478sunitinibresveratrol inhibits the reaction [sunitinib results in increased expression of NPPA mRNA]24247421
C473478sunitinibSB 203580 promotes the reaction [sunitinib results in increased expression of NPPA mRNA]24247421
C473478sunitinibsunitinib results in increased expression of NPPA mRNA24247421
D016559TacrolimusTacrolimus inhibits the reaction [NPR1 protein affects the expression of NPPA mRNA]15939815
D013749Tetrachlorodibenzodioxin[AHR protein affects the susceptibility to Tetrachlorodibenzodioxin] which affects the expression of NPPA mRNA27163630
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NPPA mRNA16120746|1797511
D013749Tetrachlorodibenzodioxinresveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NPPA mRNA]19969063
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NPPA mRNA19969063
D013755Tetradecanoylphorbol Acetate(+)-JQ1 compound inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA protein]23939492
D013755Tetradecanoylphorbol AcetateMAPK8IP1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA]11513749
D013755Tetradecanoylphorbol AcetateMifepristone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA]16533503
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of NPPA mRNA11470465|1653350
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of NPPA protein23939492
C009495titanium dioxidetitanium dioxide results in decreased expression of NPPA mRNA23557971
C009495titanium dioxidetitanium dioxide results in increased expression of NPPA mRNA27760801
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased methylation of NPPA gene26756918
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of NPPA mRNA20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of NPPA mRNA23038017
C026116torsemidetorsemide results in decreased expression of NPPA protein18154949
C447082tricarbonyldichlororuthenium (II) dimertricarbonyldichlororuthenium (II) dimer inhibits the reaction [F2 protein results in increased expression of NPPA protein]26385185
C012589trichostatin Atrichostatin A affects the expression of NPPA mRNA19729022
C012589trichostatin Atrichostatin A inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]19729022|2534189
C016167triflusaltriflusal inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]16421291
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of NPPA mRNA"26743178
D014415TunicamycinTunicamycin results in decreased expression of NPPA mRNA22378314
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]14676212
C113580U 0126U 0126 inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]12513686
D014520UrethaneUrethane results in decreased expression of NPPA mRNA28818685
D014544Uridine TriphosphateUridine Triphosphate inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]14676212
D014544Uridine TriphosphateUridine Triphosphate inhibits the reaction [MYL2 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]14676212
D014544Uridine TriphosphateUridine Triphosphate inhibits the reaction [MYOCD protein results in increased expression of NPPA protein]14676212
D014544Uridine TriphosphateUridine Triphosphate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]14676212
D014544Uridine TriphosphateUridine Triphosphate results in increased expression of NPPA mRNA14676212
D014635Valproic AcidValproic Acid results in increased methylation of NPPA gene29154799
D000068756Valsartan[Valsartan co-treated with benazepril] results in decreased expression of NPPA mRNA11136700
D000068756ValsartanValsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]23288202
D000068756ValsartanValsartan results in decreased expression of NPPA mRNA11136700
D014700Verapamil[Cilazapril co-treated with Verapamil] affects the secretion of NPPA protein1457087
D014700VerapamilVerapamil affects the secretion of NPPA protein1457087
D014700VerapamilVerapamil results in increased expression of NPPA protein11996326
C013983vinpocetinevinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]11696475
C511704xestospongin Cxestospongin C inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]16787574
C108830Y 27632Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]25449040
C108830Y 27632Y 27632 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]11739382
C108830Y 27632Y 27632 inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]25449040
D015215Zidovudine[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA11706060
D015215ZidovudineZidovudine results in increased expression of NPPA mRNA10701688
D015054ZymosanNPPA protein results in decreased susceptibility to Zymosan10330004

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005102signaling receptor binding-IDA1672777  
GO:0005102signaling receptor binding-IPI16870210  
GO:0005184neuropeptide hormone activity-IMP19646991  
GO:0005515protein binding-IPI25416956  
GO:0051427hormone receptor binding-IPI1660465  
GO:0051428peptide hormone receptor binding-IEA-  
GO:0071855neuropeptide receptor binding-IMP19646991  
GO ID GO Term Qualifier Evidence PubMed
GO:0001666response to hypoxia-IEA-  
GO:0003085negative regulation of systemic arterial blood pressure-IEA-  
GO:0006182cGMP biosynthetic process-IDA1672777  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0006457protein folding-IDA16870210  
GO:0007168receptor guanylyl cyclase signaling pathway-IDA1672777  
GO:0007218neuropeptide signaling pathway-IDA19646991  
GO:0007565female pregnancy-ISS-  
GO:0008217regulation of blood pressure-IDA6230082  6547996  
GO:0010460positive regulation of heart rate-IMP19646991  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0014898cardiac muscle hypertrophy in response to stress-IEA-  
GO:0030308negative regulation of cell growth-IEA-  
GO:0032868response to insulin-IEA-  
GO:0035994response to muscle stretch-TAS15276478  
GO:0044267cellular protein metabolic process-TAS-  
GO:0050880regulation of blood vessel size-IEA-  
GO:0060372regulation of atrial cardiac muscle cell membrane repolarization-IMP19646991  
GO:0060452positive regulation of cardiac muscle contraction-IMP19646991  
GO:0061049cell growth involved in cardiac muscle cell development-IEA-  
GO:0071260cellular response to mechanical stimulus-IEA-  
GO:1901841regulation of high voltage-gated calcium channel activity-ISS8301666  
GO:1902261positive regulation of delayed rectifier potassium channel activity-IDA8301666  19646991  
GO:1902514regulation of calcium ion transmembrane transport via high voltage-gated calcium channel-ISS8301666  
GO:1903595positive regulation of histamine secretion by mast cell-IEA-  
GO:1903766positive regulation of potassium ion export across plasma membrane-IDA8301666  19646991  
GO:1903779regulation of cardiac conduction-TAS-  
GO:1903815negative regulation of collecting lymphatic vessel constriction-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-NAS14718574  
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IEA-  
GO:0005634nucleus-IEA-  
GO:0032991protein-containing complex-IDA16870210  
GO:0042629mast cell granule-IEA-  
GO:0048471perinuclear region of cytoplasm-IEA-  
GO:0062023collagen-containing extracellular matrix-HDA27559042  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-2032785YAP1- and WWTR1 (TAZ)-stimulated gene expressionTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-397014Muscle contractionTAS
R-HSA-5576891Cardiac conductionTAS
R-HSA-5578768Physiological factorsTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-977225Amyloid fiber formationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
17036337Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. (2006 Nov 15)Carmichael SLAm J Med Genet A
17051589Selected gene polymorphisms and their interaction with maternal smoking, as risk factors for gastroschisis. (2006 Oct)Torfs CPBirth Defects Res A Clin Mol Teratol
16100725Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. (2005 Sep 15)Shaw GMAm J Med Genet A