Gene: NTF3

4908
HDNF|NGF-2|NGF2|NT-3|NT3
neurotrophin 3
protein-coding
12p13.31
Ensembl:ENSG00000185652 MIM:162660 Vega:OTTHUMG00000168649 UniprotKB:P20783
NG_050629.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.180e-1 (AD)  6.218e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs4074967chr12:5491300 (GRCh38.p7)T>C / T>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg01919377chr12:5539832NTF32.500e-10Smoking27651444

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC22A80.715
CDC20B0.706
SLC13A40.698
OR51E10.685
OR51E20.678
PLN0.672
SLC5A50.668
ALX40.664
SRL0.646
KLHL300.64

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DAPK2-0.284
TMPRSS5-0.266
ABHD1-0.26
NRN1L-0.257
KIAA1755-0.254
GNG8-0.251
FEZF2-0.244
KIF19-0.242
RHBDL2-0.241
SHC4-0.237

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in increased expression of NTF3 mRNA"23826121
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in increased expression of NTF3 protein"23826121
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"NTF3 protein affects the susceptibility to 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"23826121
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether metabolite inhibits the reaction [NTF3 protein results in increased phosphorylation of and results in increased activity of MAPK7 protein]"23564643
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimaprit results in increased expression of NTF3 protein]21276809
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NTF3 mRNA"16984957
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased transport of NTF3 protein11948662
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NTF3 mRNA"16984957
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NTF3 mRNA"20959002
C496492abrineabrine results in increased expression of NTF3 mRNA22595364
D000082AcetaminophenAcetaminophen results in decreased expression of NTF3 mRNA22230336
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NTF3 protein]26138014
D020106AcrylamideNTF3 protein inhibits the reaction [Acrylamide results in decreased activity of CHAT protein]11779407
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of NTF3 gene27153756
D0151206-Aminonicotinamide6-Aminonicotinamide results in increased expression of NTF3 protein12898533
D0151206-AminonicotinamideIL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of NTF3 protein]12898533
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NTF3 mRNA16483693
D000661AmphetamineAmphetamine affects the expression of NTF3 protein17512948
D000661AmphetamineLithium inhibits the reaction [Amphetamine affects the expression of NTF3 protein]17512948
D000661AmphetamineValproic Acid inhibits the reaction [Amphetamine affects the expression of NTF3 protein]17512948
D001151ArsenicArsenic affects the expression of NTF3 protein24675094
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of NTF3 mRNA26377693
D001554Benzene[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in increased expression of NTF3 protein22863854
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NTF3 mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NTF3 mRNA22228805|2719552
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NTF3 mRNA21839799
D004958EstradiolEstradiol results in increased expression of NTF3 protein15570173
D004958EstradiolProgesterone inhibits the reaction [Estradiol results in increased expression of NTF3 protein]15570173
C006780bisphenol Abisphenol A results in decreased expression of NTF3 mRNA29275510
C006780bisphenol Abisphenol A affects the expression of NTF3 mRNA25181051
C006780bisphenol A[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NTF3 promoter23359474
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NTF3 protein]26138014
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of NTF3 protein26138014
D000001CalcimycinCalcimycin results in increased expression of NTF3 protein19854260
D002248Carbon MonoxideCarbon Monoxide results in decreased expression of and results in decreased secretion of NTF3 protein27113706
D002248Carbon MonoxideCarbon Monoxide results in decreased expression of NTF3 mRNA27113706
D002518CeramidesCeramides promotes the reaction [NTF3 protein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]20696185
D002518CeramidesCeramides promotes the reaction [NTF3 protein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]20696185
D002518CeramidesNTF3 protein results in decreased susceptibility to Ceramides20696185
D004390ChlorpyrifosChlorpyrifos results in decreased expression of NTF3 mRNA18502319
D002927CimetidineCimetidine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
C115705ciproxifanciproxifan inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
C115705ciproxifan[Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D005576ColforsinColforsin results in increased expression of NTF3 protein19854260
D003520CyclophosphamideCyclophosphamide results in increased expression of NTF3 mRNA10683293
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of NTF3 mRNA23640034
C014347decitabinedecitabine affects the expression of NTF3 mRNA23300844
D003993Dibutyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NTF3 promoter23359474
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of NTF3 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NTF3 mRNA17379624
D003994BucladesineBucladesine results in increased expression of NTF3 protein19854260
D002945CisplatinCisplatin affects the expression of NTF3 mRNA23300844
D004051Diethylhexyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NTF3 promoter23359474
C014476diethyl maleatediethyl maleate results in decreased expression of NTF3 mRNA21161181
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NTF3 mRNA18164116
D017259Dimaprit2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimaprit results in increased expression of NTF3 protein]21276809
D017259DimapritDimaprit results in increased expression of NTF3 protein21276809
D017259Dimaprit[methylhistaprodifen co-treated with Dimaprit co-treated with imetit] results in increased expression of NTF3 protein21276809
D017259Dimaprit[methylhistaprodifen co-treated with Dimaprit] results in increased expression of NTF3 protein21276809
D017259DimapritN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dimaprit results in increased expression of NTF3 protein]21276809
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of NTF3 mRNA"19480007
D004298DopamineDopamine results in increased expression of NTF3 mRNA19854260
D004298DopamineDopamine results in increased expression of NTF3 protein19854260
D004837EpinephrineEpinephrine results in increased expression of NTF3 mRNA19854260
D004837EpinephrineEpinephrine results in increased expression of NTF3 protein19854260
D015738FamotidineFamotidine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D015738Famotidine[Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D015738Famotidine[Pyrilamine co-treated with Famotidine] inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D005557Formaldehyde[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in increased expression of NTF3 protein22863854
D005557FormaldehydeFormaldehyde results in increased expression of NTF3 mRNA19904815
C039281furanfuran results in decreased expression of NTF3 mRNA25539665|2619464
D005839GentamicinsNTF3 protein results in decreased susceptibility to Gentamicins18024279
C004312glycidolglycidol results in decreased expression of NTF3 mRNA24915197
D006632Histamine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistamineCimetidine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632Histamineciproxifan inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistamineFamotidine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistamineHistamine results in increased expression of NTF3 mRNA21276809
D006632HistamineHistamine results in increased expression of NTF3 protein21276809
D006632HistamineKN 62 inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistamineN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistaminePertussis Toxin inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632Histamine[Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632Histamine[Pyrilamine co-treated with Famotidine] inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistaminePyrilamine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistamineStaurosporine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistamineTetradecanoylphorbol Acetate inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632Histaminethioperamide inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006632HistamineTriprolidine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of NTF3 mRNA20044591
C077430imetit2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
C077430imetitimetit results in increased expression of NTF3 protein21276809
C077430imetit[methylhistaprodifen co-treated with Dimaprit co-treated with imetit] results in increased expression of NTF3 protein21276809
C077430imetitPertussis Toxin inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
C077430imetitStaurosporine inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
C077430imetitTetradecanoylphorbol Acetate inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
C016517indole-3-carbinolindole-3-carbinol affects the expression of NTF3 mRNA21396975
D007545IsoproterenolIsoproterenol results in decreased expression of NTF3 mRNA20003209
D007649KetamineKetamine results in decreased expression of NTF3 mRNA20080153
C063302KN 62KN 62 inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
C063302KN 62KN 62 inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
C008261lead acetatelead acetate results in decreased expression of NTF3 mRNA22160880
D008094LithiumLithium inhibits the reaction [Amphetamine affects the expression of NTF3 protein]17512948
D008094LithiumLithium results in increased expression of NTF3 protein17512948
D015122MercaptopurineMercaptopurine results in increased expression of NTF3 mRNA23358152
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of NTF3 mRNA16507785
C118995methylhistaprodifen2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
C118995methylhistaprodifenKN 62 inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
C118995methylhistaprodifen[methylhistaprodifen co-treated with Dimaprit co-treated with imetit] results in increased expression of NTF3 protein21276809
C118995methylhistaprodifen[methylhistaprodifen co-treated with Dimaprit] results in increased expression of NTF3 protein21276809
C118995methylhistaprodifenmethylhistaprodifen results in increased expression of NTF3 protein21276809
C118995methylhistaprodifenStaurosporine inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
C118995methylhistaprodifenTetradecanoylphorbol Acetate inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
D009151Mustard GasIL10 protein affects the reaction [Mustard Gas affects the expression of NTF3 mRNA]16173061
D009151Mustard GasMustard Gas results in decreased expression of NTF3 mRNA16173061
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dimaprit results in increased expression of NTF3 protein]21276809
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Neurotransmitter Agents results in increased expression of NTF3 protein]19854260
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of NTF3 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of NTF3 mRNA"25554681|2562005
D018377Neurotransmitter AgentsN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Neurotransmitter Agents results in increased expression of NTF3 protein]19854260
D018377Neurotransmitter AgentsNeurotransmitter Agents results in increased expression of NTF3 protein19854260
D018377Neurotransmitter AgentsStaurosporine inhibits the reaction [Neurotransmitter Agents results in increased expression of NTF3 protein]19854260
D009638NorepinephrineNorepinephrine results in increased expression of NTF3 mRNA19854260
D009638NorepinephrineNorepinephrine results in increased expression of NTF3 protein19854260
C009618O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate"O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of NTF3 mRNA"20701988
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
D010672PhenytoinPhenytoin results in decreased expression of NTF3 mRNA7841657
D010862PilocarpinePilocarpine results in decreased expression of NTF3 mRNA8635431
D010862PilocarpineScopolamine Hydrobromide inhibits the reaction [Pilocarpine results in decreased expression of NTF3 mRNA]8635431
C006253pirinixic acidpirinixic acid results in decreased expression of NTF3 mRNA19162173
D011188Potassium[Potassium results in increased expression of BDNF] which results in increased expression of NTF38978711
D011188PotassiumPotassium affects the susceptibility to NTF3 protein8978711
D011192Potassium DichromatePotassium Dichromate results in decreased expression of NTF3 mRNA23608068
D011374ProgesteroneProgesterone inhibits the reaction [Estradiol results in increased expression of NTF3 protein]15570173
D011738Pyrilamine[Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D011738Pyrilamine[Pyrilamine co-treated with Famotidine] inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D011738PyrilaminePyrilamine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D012601Scopolamine HydrobromideScopolamine Hydrobromide inhibits the reaction [Pilocarpine results in decreased expression of NTF3 mRNA]8635431
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of NTF3 mRNA23806026
C017947sodium arsenitesodium arsenite affects the methylation of NTF3 gene28589171
D012999SomanSoman results in decreased expression of NTF3 mRNA19281266
D019311StaurosporineStaurosporine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D019311StaurosporineStaurosporine inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
D019311StaurosporineStaurosporine inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
D019311StaurosporineStaurosporine inhibits the reaction [Neurotransmitter Agents results in increased expression of NTF3 protein]19854260
D013311StreptozocinStreptozocin affects the localization of NTF3 protein12031555
D013749TetrachlorodibenzodioxinAHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NTF3 mRNA]16984957
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NTF3 mRNA16984957
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NTF3 mRNA20959002|2121527
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [imetit results in increased expression of NTF3 protein]21276809
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]21276809
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of NTF3 protein19854260
D013853ThioacetamideThioacetamide results in decreased expression of NTF3 mRNA23411599
C052075thioperamidethioperamide inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
D014050Toluene[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in increased expression of NTF3 protein22863854
D014212Tretinoin[NTF3 protein co-treated with Tretinoin] results in increased expression of DLG4 protein16996685
D014212Tretinoin[NTF3 protein co-treated with Tretinoin] results in increased expression of MAP2 protein16996685
D014212Tretinoin[NTF3 protein co-treated with Tretinoin] results in increased expression of NES protein16996685
D014212Tretinoin[NTF3 protein co-treated with Tretinoin] results in increased expression of NTRK3 mRNA16996685
D014212TretinoinTretinoin results in decreased expression of NTF3 mRNA21934132
D014212Tretinoin[Tretinoin co-treated with BDNF protein co-treated with NTF3 protein] results in decreased expression of MAP2 protein16646665
D014241TrichloroethyleneTrichloroethylene results in decreased expression of NTF3 mRNA22421312
C012589trichostatin Atrichostatin A results in decreased expression of NTF3 mRNA24935251|2627250
C046488trimethyltintrimethyltin results in decreased expression of NTF3 mRNA24002884
D014311TriprolidineTriprolidine inhibits the reaction [Histamine results in increased expression of NTF3 protein]21276809
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of NTF3 mRNA"26552522
D014635Valproic AcidValproic Acid results in decreased expression of NTF3 mRNA24383497|2493525
D014635Valproic AcidValproic Acid affects the expression of NTF3 mRNA17963808
D014635Valproic AcidValproic Acid inhibits the reaction [Amphetamine affects the expression of NTF3 protein]17512948
D014635Valproic AcidValproic Acid results in increased expression of NTF3 protein17512948
D014638VanadatesVanadates results in increased expression of NTF3 mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of NTF3 gene25560391
D024483Vitamin K 3Vitamin K 3 affects the expression of NTF3 mRNA20044591
C009687wortmanninwortmannin results in decreased transport of NTF3 protein11948662
D014992Xylenes[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in increased expression of NTF3 protein22863854

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005102signaling receptor binding-TAS2236018  
GO:0005515protein binding-IPI18596692  25416956  
GO:0008083growth factor activity-IBA21873635  
GO:0008083growth factor activity-IDA23027130  
GO:0042056chemoattractant activity-IDA23027130  
GO ID GO Term Qualifier Evidence PubMed
GO:0000187activation of MAPK activity-IDA23027130  
GO:0002092positive regulation of receptor internalization-IDA23027130  
GO:0007165signal transduction-TAS2236018  
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway-IBA21873635  
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway-IDA23027130  
GO:0007267cell-cell signaling-IBA21873635  
GO:0007267cell-cell signaling-TAS2236018  
GO:0007399nervous system development-TAS1542658  
GO:0007422peripheral nervous system development-IBA21873635  
GO:0007613memory-IBA21873635  
GO:0008284positive regulation of cell proliferation-IDA23027130  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0021675nerve development-IBA21873635  
GO:0030335positive regulation of cell migration-IDA23027130  
GO:0032148activation of protein kinase B activity-IDA23027130  
GO:0033138positive regulation of peptidyl-serine phosphorylation-IDA23027130  
GO:0038180nerve growth factor signaling pathway-IBA21873635  
GO:0040011locomotion-IBA21873635  
GO:0042981regulation of apoptotic process-IGI23954828  
GO:0043524negative regulation of neuron apoptotic process-IBA21873635  
GO:0045664regulation of neuron differentiation-IBA21873635  
GO:0048812neuron projection morphogenesis-IBA21873635  
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation-IDA23027130  
GO:0050732negative regulation of peptidyl-tyrosine phosphorylation-IDA23027130  
GO:0050804modulation of chemical synaptic transmission-IBA21873635  
GO:0050918positive chemotaxis-IEA-  
GO:0050930induction of positive chemotaxis-IDA23027130  
GO:0090630activation of GTPase activity-IDA23027130  
GO:2000251positive regulation of actin cytoskeleton reorganization-IDA23027130  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IBA21873635  
GO:0008021synaptic vesicle-IBA21873635  
GO:0030424axon-IBA21873635  
GO:0030425dendrite-IBA21873635  
GO:0031410cytoplasmic vesicle-IBA21873635  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04722Neurotrophin signaling pathway
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionIEA
R-HSA-166520Signaling by NTRKsIEA
R-HSA-9006115Signaling by NTRK2 (TRKB)IEA
R-HSA-9006934Signaling by Receptor Tyrosine KinasesIEA
R-HSA-9025046NTF3 activates NTRK2 (TRKB) signalingIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal