Gene info: ID 4968

Gene: OGG1

GENE ID: 4968

Synonyms: HMMH|HOGG1|MUTM|OGH1

Description: 8-oxoguanine DNA glycosylase

Gene type: protein-coding

Location: 3p25.3

dbXrefs: Ensembl:ENSG00000114026 MIM:601982 Vega:OTTHUMG00000097091 UniprotKB:O15527

RefSeq: NG_012106.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 72

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 6.179e-1 (AD) 9.553e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
PYCR2	0.845
COG4	0.837
INO80E	0.833
TCTA	0.83
PHB	0.829
KEAP1	0.826
ELP6	0.825
URM1	0.825
YIPF3	0.825
NUDT16L1	0.824

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.699
OR4F29	-0.657
MTRNR2L6	-0.285
IL18RAP	-0.274
CLEC6A	-0.269
HBD	-0.266
C17orf112	-0.265
SPRR4	-0.262
SLC26A7	-0.262
IYD	-0.262

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of OGG1 mRNA"	19114083
C016403	2,4-dinitrotoluene	"2,4-dinitrotoluene affects the expression of OGG1 mRNA"	21346803
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of OGG1 protein	19631197
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	butin inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of OGG1 protein]	19631197
C071023	2,6-diamino-4-hydroxy-5-formamidopyrimidine	"OGG1 protein affects the metabolism of 2,6-diamino-4-hydroxy-5-formamidopyrimidine"	20067321
C014970	2-aminodiphenyl	2-aminodiphenyl results in decreased expression of OGG1 mRNA	16112689
C014970	2-aminodiphenyl	2-aminodiphenyl results in decreased expression of OGG1 protein	16112689
C026832	3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenz(a)anthracene	"3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenz(a)anthracene results in increased expression of OGG1 mRNA"	22236718
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OGG1 mRNA"	27188386
C006757	4-biphenylamine	4-biphenylamine results in decreased expression of OGG1 mRNA	16112689
C006757	4-biphenylamine	4-biphenylamine results in decreased expression of OGG1 protein	16112689
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OGG1 mRNA"	27188386
C453560	7,8-dihydro-8-oxoguanine	"OGG1 protein results in decreased abundance of 7,8-dihydro-8-oxoguanine"	21873502
C453560	7,8-dihydro-8-oxoguanine	"OGG1 protein affects the reaction [Methamphetamine results in increased abundance of 7,8-dihydro-8-oxoguanine]"	18768699
C024829	8-hydroxyguanine	OGG1 protein results in decreased abundance of 8-hydroxyguanine	21925250
C078307	8-oxo-7,8-dihydrodeoxyguanine	"[OGG1 protein polymorphism co-treated with Tobacco Smoke Pollution] affects the abundance of 8-oxo-7,8-dihydrodeoxyguanine"	23376476
C067134	8-oxo-7-hydrodeoxyguanosine	OGG1 protein results in increased cleavage of 8-oxo-7-hydrodeoxyguanosine	19193190
C067134	8-oxo-7-hydrodeoxyguanosine	thymidine glycol inhibits the reaction [OGG1 protein results in increased cleavage of 8-oxo-7-hydrodeoxyguanosine]	19193190
C067134	8-oxo-7-hydrodeoxyguanosine	thymidine glycol promotes the reaction [OGG1 protein results in increased cleavage of 8-oxo-7-hydrodeoxyguanosine]	19193190
D000082	Acetaminophen	Acetaminophen results in increased expression of OGG1 mRNA	25704631\|2906747
D000082	Acetaminophen	Acetaminophen affects the expression of OGG1 mRNA	17562736
D000082	Acetaminophen	Acetaminophen results in increased expression of OGG1 mRNA	12540782
D000082	Acetaminophen	"O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of OGG1 mRNA]"	12540782
D000082	Acetaminophen	Acetaminophen results in increased expression of OGG1 mRNA	16751229
D000171	Acrolein	OGG1 protein affects the susceptibility to Acrolein	17003489
D020106	Acrylamide	Acrylamide results in increased expression of OGG1 mRNA	28959563
D012435	S-Adenosylhomocysteine	Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased expression of OGG1 protein]	22064374
D012435	S-Adenosylhomocysteine	Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased methylation of OGG1 promoter]	22064374
D012435	S-Adenosylhomocysteine	S-Adenosylhomocysteine inhibits the reaction [DNMT1 protein binds to OGG1 promoter]	22064374
D012435	S-Adenosylhomocysteine	S-Adenosylhomocysteine results in decreased expression of OGG1 mRNA	22064374
D012435	S-Adenosylhomocysteine	S-Adenosylhomocysteine results in decreased expression of OGG1 protein	22064374
D012435	S-Adenosylhomocysteine	S-Adenosylhomocysteine results in decreased methylation of OGG1 promoter	22064374
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of OGG1 protein	24675474
D000393	Air Pollutants	OGG1 gene SNP affects the susceptibility to Air Pollutants	23951099
D000393	Air Pollutants	Air Pollutants results in increased expression of OGG1 mRNA	24792328
D000393	Air Pollutants	NCF1 gene mutant form inhibits the reaction [Air Pollutants results in increased expression of OGG1 mRNA]	24792328
D000395	Air Pollutants, Occupational	"OGG1 gene polymorphism affects the susceptibility to Air Pollutants, Occupational"	20723587
C040534	alpha-hexachlorocyclohexane	[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of OGG1 mRNA	16246485
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of OGG1 mRNA	16483693
C023650	aniline	aniline results in increased expression of OGG1	21145906\|2335289
D018501	Antirheumatic Agents	Antirheumatic Agents results in increased expression of OGG1 mRNA	24449571
D001151	Arsenic	Arsenic affects the expression of OGG1	21235219
D001151	Arsenic	Arsenic results in decreased expression of OGG1 mRNA	20478284
D001151	Arsenic	Arsenic results in decreased expression of OGG1 protein	20478284
D001151	Arsenic	Arsenic results in increased expression of OGG1 mRNA	16759981\|2133209
D001151	Arsenic	Arsenic results in increased expression of OGG1 protein	21332098
D001151	Arsenic	Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 mRNA]	21332098
D001151	Arsenic	Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 protein]	21332098
D001151	Arsenic	[Selenium co-treated with Arsenic] results in increased expression of OGG1 protein	20478284
D001151	Arsenic	Arsenic results in increased expression of OGG1 mRNA	22641096
C006632	arsenic trioxide	arsenic trioxide results in decreased expression of OGG1 mRNA	20458559
C006632	arsenic trioxide	OGG1 protein affects the activity of arsenic trioxide	17101720
C015001	arsenite	OGG1 gene mutant form results in increased susceptibility to arsenite	24190502
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of OGG1 mRNA"	11181447
D017638	Asbestos, Crocidolite	"OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of CASP3 protein modified form]"	24918270
D017638	Asbestos, Crocidolite	"OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of HSPA5 protein]"	24918270
D017638	Asbestos, Crocidolite	"OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of TRP53 protein]"	24918270
D017638	Asbestos, Crocidolite	"OGG1 protein mutant form results in increased susceptibility to Asbestos, Crocidolite"	24918270
D001312	Aurintricarboxylic Acid	Aurintricarboxylic Acid results in decreased activity of OGG1 protein	26218629
D001374	Azacitidine	Azacitidine results in decreased expression of OGG1 protein	22064374
D001374	Azacitidine	Azacitidine results in decreased methylation of OGG1 promoter	22064374
D001554	Benzene	OGG1 gene SNP results in increased susceptibility to Benzene	16600130
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of OGG1 mRNA	26238291
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of OGG1 protein	29145655
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of OGG1 mRNA	29145655
C032776	beryllium chloride	beryllium chloride affects the expression of OGG1 mRNA	23793613
D004958	Estradiol	decitabine affects the reaction [Estradiol affects the expression of OGG1 mRNA]	22082530
D004958	Estradiol	Estradiol affects the expression of OGG1 mRNA	22082530
D004958	Estradiol	[Estradiol results in increased expression of OGG1 mRNA] which results in increased susceptibility to Cisplatin	28323900
D004958	Estradiol	[Estradiol results in increased expression of OGG1 mRNA] which results in increased susceptibility to Doxorubicin	28323900
D004958	Estradiol	Estradiol results in decreased expression of OGG1 mRNA	24894866
D004958	Estradiol	Estradiol results in decreased expression of OGG1 protein	24894866
D004958	Estradiol	resveratrol inhibits the reaction [Estradiol results in decreased expression of OGG1 mRNA]	24894866
D004958	Estradiol	resveratrol inhibits the reaction [Estradiol results in decreased expression of OGG1 protein]	24894866
D001622	Betaine	Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased expression of OGG1 protein]	22064374
D001622	Betaine	Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased methylation of OGG1 promoter]	22064374
D001629	Bezafibrate	Bezafibrate results in increased expression of OGG1 mRNA	15447978
C543008	bis(4-hydroxyphenyl)sulfone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of OGG1 mRNA	28628672
C006780	bisphenol A	bisphenol A affects the expression of OGG1 mRNA	25181051
C000611646	bisphenol F	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of OGG1 mRNA	28628672
C051437	butin	butin inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of OGG1 protein]	19631197
C051437	butin	butin inhibits the reaction [Hydrogen Peroxide results in decreased expression of OGG1 mRNA]	19631197
C051437	butin	butin inhibits the reaction [Hydrogen Peroxide results in decreased expression of OGG1 protein]	19631197
C051437	butin	butin results in increased expression of OGG1 mRNA	19631197
C051437	butin	butin results in increased expression of OGG1 protein	19631197
D002084	Butylated Hydroxytoluene	Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of OGG1 mRNA]	20676402
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA1B mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA4L mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA8 mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPB1 mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPH1 mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of AOC3 mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CCNC mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CDH4 mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CFD mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CYP7B1 mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of KPNB1 mRNA]	17441966
D002101	Cacodylic Acid	OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of MMP13 mRNA]	17441966
D002101	Cacodylic Acid	Cacodylic Acid results in increased expression of OGG1 mRNA	17481689
D002104	Cadmium	Cadmium affects the activity of OGG1 protein	21605570
D002104	Cadmium	Cadmium inhibits the reaction [SP1 protein binds to OGG1 promoter]	15760895
D002104	Cadmium	[Cadmium inhibits the reaction [SP1 protein binds to OGG1 promoter]] which results in decreased expression of OGG1 mRNA	15760895\|1576089
D002104	Cadmium	Cadmium results in decreased expression of OGG1 mRNA	15760895
D002104	Cadmium	Cadmium results in decreased expression of OGG1 protein	15760895
D002104	Cadmium	Cadmium results in increased oxidation of and results in decreased activity of OGG1 protein	16923968
D002104	Cadmium	Cadmium results in decreased activity of OGG1 protein	16677676
D019256	Cadmium Chloride	[Cadmium Chloride co-treated with titanium dioxide] results in increased expression of OGG1 mRNA	21671166
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of OGG1 mRNA	22112500\|2647268
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of OGG1 protein	22112500
D019256	Cadmium Chloride	[Cadmium Chloride results in increased activity of [DNMT1 protein co-treated with DNMT3A protein]] which results in decreased expression of OGG1 mRNA	22112500
D019256	Cadmium Chloride	[Cadmium Chloride results in increased activity of [DNMT1 protein co-treated with DNMT3A protein]] which results in increased methylation of OGG1 promoter	22112500
D019256	Cadmium Chloride	Cadmium Chloride results in increased methylation of OGG1 promoter	22112500
D019256	Cadmium Chloride	decitabine inhibits the reaction [Cadmium Chloride results in decreased expression of OGG1 mRNA]	22112500
D019256	Cadmium Chloride	decitabine inhibits the reaction [Cadmium Chloride results in decreased expression of OGG1 protein]	22112500
C037123	cadmium sulfate	cadmium sulfate affects the expression of OGG1 mRNA	23770381
C028337	cadmium telluride	cadmium telluride analog affects the expression of OGG1 mRNA	23770381
C006698	carbendazim	carbendazim affects the expression of OGG1 mRNA	26055223
C006698	carbendazim	carbendazim results in decreased expression of OGG1 mRNA	25304545
D002244	Carbon	Carbon analog results in increased expression of OGG1 mRNA	24792328
D002244	Carbon	NCF1 gene mutant form inhibits the reaction [Carbon analog results in increased expression of OGG1 mRNA]	24792328
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of OGG1 mRNA	17484886
D002251	Carbon Tetrachloride	[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of OGG1 mRNA	23288052
D002330	Carmustine	OGG1 protein results in decreased susceptibility to Carmustine	11181913\|1174181
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of OGG1 mRNA	25113976
C074702	chromium hexavalent ion	chromium hexavalent ion affects the expression of OGG1 mRNA	23050433
C074702	chromium hexavalent ion	chromium hexavalent ion affects the expression of OGG1 protein	23050433
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of OGG1 mRNA	19320972
C408982	CPG-oligonucleotide	CPG-oligonucleotide results in increased expression of OGG1 mRNA	21878529
D003474	Curcumin	Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 mRNA]	21332098
D003474	Curcumin	Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 protein]	21332098
D003520	Cyclophosphamide	Cyclophosphamide results in decreased expression of OGG1 protein	27032448
C017160	cypermethrin	cypermethrin results in decreased expression of OGG1 mRNA	21840035
D003634	DDT	[DDT co-treated with Diethylnitrosamine] results in decreased expression of OGG1 mRNA	15885732
D003634	DDT	[DDT co-treated with Diethylnitrosamine] results in increased expression of OGG1 mRNA	15885732
D003634	DDT	DDT results in increased expression of OGG1 mRNA	11948501
C014347	decitabine	decitabine affects the reaction [Estradiol affects the expression of OGG1 mRNA]	22082530
C014347	decitabine	decitabine inhibits the reaction [Cadmium Chloride results in decreased expression of OGG1 mRNA]	22112500
C014347	decitabine	decitabine inhibits the reaction [Cadmium Chloride results in decreased expression of OGG1 protein]	22112500
C014347	decitabine	decitabine results in increased expression of OGG1 mRNA	22082530
D015255	Idarubicin	Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of OGG1 mRNA]	28973540
D015255	Idarubicin	Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of OGG1 protein]	28973540
D015255	Idarubicin	Idarubicin results in decreased expression of OGG1 mRNA	28973540
D015255	Idarubicin	Idarubicin results in decreased expression of OGG1 protein	28973540
C007262	deoxynivalenol	deoxynivalenol results in increased expression of OGG1 mRNA	24355168
C007262	deoxynivalenol	deoxynivalenol results in increased expression of OGG1 protein	24355168
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of OGG1 mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of OGG1 mRNA	28628672
D064730	Dexrazoxane	Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of OGG1 mRNA]	28973540
D064730	Dexrazoxane	Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of OGG1 protein]	28973540
D064730	Dexrazoxane	Dexrazoxane results in increased expression of OGG1 mRNA	28973540
D003958	Diamide	Diamide results in increased oxidation of and results in decreased activity of OGG1 protein	16923968
D002945	Cisplatin	[Estradiol results in increased expression of OGG1 mRNA] which results in increased susceptibility to Cisplatin	28323900
C121718	dicyclanil	[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of OGG1 mRNA	20118626
D004041	Dietary Fats	OGG1 results in decreased susceptibility to Dietary Fats	23284747
C014476	diethyl maleate	[diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of OGG1 mRNA	22564015
D004052	Diethylnitrosamine	[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of OGG1 mRNA	20118626
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of OGG1 mRNA	23288052
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of OGG1 mRNA	20101389
D004052	Diethylnitrosamine	[DDT co-treated with Diethylnitrosamine] results in decreased expression of OGG1 mRNA	15885732
D004052	Diethylnitrosamine	[DDT co-treated with Diethylnitrosamine] results in increased expression of OGG1 mRNA	15885732
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of OGG1 mRNA	16246485
D004052	Diethylnitrosamine	[Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of OGG1 mRNA	18977376
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of OGG1 mRNA"	25697376
D015127	9,10-Dimethyl-1,2-benzanthracene	"Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of OGG1 mRNA]"	25697376
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of OGG1 mRNA	19031421
D004317	Doxorubicin	[Estradiol results in increased expression of OGG1 mRNA] which results in increased susceptibility to Doxorubicin	28323900
C118739	entinostat	entinostat results in decreased expression of OGG1 mRNA	26272509
C118739	entinostat	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OGG1 mRNA"	27188386
D004785	Environmental Pollutants	OGG1 gene SNP affects the susceptibility to Environmental Pollutants	24036326
D000431	Ethanol	Ethanol results in increased expression of OGG1 mRNA	22056336
D000431	Ethanol	Ethanol results in increased expression of OGG1 protein	22056336
D000431	Ethanol	OGG1 mutant form results in increased susceptibility to Ethanol	25354798
D000431	Ethanol	phenyl-N-tert-butylnitrone inhibits the reaction [OGG1 mutant form results in increased susceptibility to Ethanol]	25354798
D000431	Ethanol	[BRCA1 protein affects the expression of OGG1 mRNA] which affects the susceptibility to Ethanol	26629949
D005027	Ethylene Oxide	OGG1 protein affects the susceptibility to Ethylene Oxide	16386346
D005027	Ethylene Oxide	Ethylene Oxide results in increased expression of OGG1 protein	16051529
C098546	ethyl tert-butyl ether	ethyl tert-butyl ether results in decreased expression of OGG1 mRNA	24090815
D005047	Etoposide	Etoposide results in decreased expression of OGG1 mRNA	23872129
D005047	Etoposide	wogonin inhibits the reaction [Etoposide results in decreased expression of OGG1 mRNA]	23872129
C017690	fenvalerate	fenvalerate results in decreased expression of OGG1 mRNA	20570613
D005395	Fish Oils	Fish Oils results in decreased expression of OGG1 mRNA	28659405
D005485	Flutamide	Flutamide results in increased expression of OGG1 mRNA	24793618
C069837	fullerene C60	fullerene C60 results in increased expression of OGG1 mRNA	19479010
C039281	furan	furan results in decreased expression of OGG1 mRNA	22507866
D005978	Glutathione	[diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of OGG1 mRNA	22564015
D006046	Gold	[Polyethyleneimine binds to Gold] which results in decreased expression of OGG1 mRNA	28433809
C089796	hexabromocyclododecane	hexabromocyclododecane results in increased expression of OGG1 mRNA	27718427
D006830	Hydralazine	[Hydralazine co-treated with Valproic Acid] results in increased expression of OGG1 mRNA	17183730
D006834	Hydrazines	Hydrazines analog results in decreased activity of OGG1 protein	26218629
D006861	Hydrogen Peroxide	butin inhibits the reaction [Hydrogen Peroxide results in decreased expression of OGG1 mRNA]	19631197
D006861	Hydrogen Peroxide	butin inhibits the reaction [Hydrogen Peroxide results in decreased expression of OGG1 protein]	19631197
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in decreased expression of OGG1 mRNA	19631197
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in decreased expression of OGG1 protein	19631197
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased expression of OGG1 mRNA	19651184
D006861	Hydrogen Peroxide	[NUDT1 mutant form results in increased susceptibility to Hydrogen Peroxide] which results in increased expression of OGG1 mRNA	25127756
D006861	Hydrogen Peroxide	OGG1 mutant form results in increased susceptibility to Hydrogen Peroxide	25127756
D006861	Hydrogen Peroxide	[OGG1 mutant form results in increased susceptibility to Hydrogen Peroxide] which results in increased expression of NUDT1 mRNA	25127756
D006861	Hydrogen Peroxide	Quercetin promotes the reaction [Hydrogen Peroxide results in increased expression of OGG1 mRNA]	19651184
C082359	imidacloprid	imidacloprid results in increased expression of OGG1 mRNA	27914857
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of OGG1 mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of OGG1 mRNA	28628672
C051140	iron(II)-ascorbic acid complex	Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of OGG1 mRNA]	20676402
C051140	iron(II)-ascorbic acid complex	iron(II)-ascorbic acid complex results in decreased expression of OGG1 mRNA	20676402
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of OGG1 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of OGG1 mRNA	28628672
C544151	jinfukang	jinfukang results in increased expression of OGG1 mRNA	27392435
D007854	Lead	OGG1 gene polymorphism affects the susceptibility to Lead	22466227
D007854	Lead	Lead results in decreased expression of OGG1 mRNA	22641096
D008094	Lithium	Lithium results in decreased expression of OGG1 mRNA	22641096
C010480	lupeol	lupeol inhibits the reaction [mancozeb results in decreased expression of OGG1 mRNA]	27235710
C048341	mafosfamide	OGG1 protein results in decreased susceptibility to mafosfamide	11181913
C013099	mancozeb	lupeol inhibits the reaction [mancozeb results in decreased expression of OGG1 mRNA]	27235710
C013099	mancozeb	mancozeb results in decreased expression of OGG1 mRNA	27235710
D008345	Manganese	Manganese results in decreased expression of OGG1 mRNA	22641096
D000069997	Mastic Resin	[Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of OGG1 mRNA	18977376
D008628	Mercury	Mercury results in decreased expression of OGG1 mRNA	22641096
D058955	Metalloids	OGG1 gene SNP affects the susceptibility to Metalloids	24036326
D008670	Metals	OGG1 gene SNP affects the susceptibility to Metals	24036326
D008687	Metformin	"Metformin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of OGG1 mRNA]"	25697376
D008694	Methamphetamine	"OGG1 protein affects the reaction [Methamphetamine results in increased abundance of 7,8-dihydro-8-oxoguanine]"	18768699
D008694	Methamphetamine	OGG1 protein affects the susceptibility to Methamphetamine	18768699
D008694	Methamphetamine	[Methamphetamine co-treated with SCH 23390] results in decreased expression of OGG1 mRNA	19564919
D008694	Methamphetamine	Methamphetamine results in decreased expression of OGG1 mRNA	19564919
D008694	Methamphetamine	[BRCA1 protein affects the expression of OGG1 mRNA] which affects the susceptibility to Methamphetamine	26629949
C005223	methyleugenol	methyleugenol results in decreased expression of OGG1 mRNA	21659616
D008767	Methylmercury Compounds	OGG1 protein results in increased susceptibility to Methylmercury Compounds	23607987
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"OGG1 gene mutant form results in increased susceptibility to N-Methyl-3,4-methylenedioxyamphetamine"	26629949
C043243	methyl tert-butyl ether	methyl tert-butyl ether results in increased expression of OGG1 mRNA	19150650
D008825	Miconazole	Miconazole results in decreased expression of OGG1 mRNA	22262564
D016685	Mitomycin	Mitomycin results in decreased expression of OGG1 protein	27032448
C020300	monomethylarsonic acid	monomethylarsonic acid results in increased expression of OGG1 mRNA	17481689
C005246	myristicin	myristicin results in decreased expression of OGG1 mRNA	24792648
D009532	Nickel	Nickel results in decreased expression of OGG1 mRNA	22641096
C474958	O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate	"OGG1 protein affects the susceptibility to O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"	20962031
C107010	O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate	"O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of OGG1 mRNA]"	12540782
C025589	ochratoxin A	ochratoxin A results in decreased expression of OGG1 mRNA	23358140
C118580	octylmethoxycinnamate	octylmethoxycinnamate results in decreased expression of OGG1 mRNA	20071424
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in decreased expression of OGG1 mRNA	25729387
D010100	Oxygen	Oxygen deficiency results in decreased expression of OGG1 protein	25030372
D017239	Paclitaxel	Paclitaxel results in increased expression of OGG1 protein	15907983
D052638	Particulate Matter	Particulate Matter results in increased expression of OGG1 mRNA	12919962
D052638	Particulate Matter	Particulate Matter results in increased expression of OGG1 mRNA	10426809\|1291996
D010575	Pesticides	OGG1 gene alternative form results in increased susceptibility to Pesticides	20209647
D010575	Pesticides	OGG1 polymorphism affects the susceptibility to Pesticides	21640155
D010634	Phenobarbital	Phenobarbital results in increased expression of OGG1 mRNA	12807726
D010634	Phenobarbital	Phenobarbital results in decreased expression of OGG1 mRNA	24090815
C029217	phenyl-N-tert-butylnitrone	phenyl-N-tert-butylnitrone inhibits the reaction [OGG1 mutant form results in increased susceptibility to Ethanol]	25354798
D010862	Pilocarpine	Pilocarpine results in decreased expression of OGG1 mRNA	20206232
D010862	Pilocarpine	Pilocarpine results in decreased expression of OGG1 protein	20206232
D010882	Piperonyl Butoxide	[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of OGG1 mRNA	20101389
D011094	Polyethyleneimine	[Polyethyleneimine binds to Gold] which results in decreased expression of OGG1 mRNA	28433809
C019536	potassium bromate	OGG1 gene mutant form results in decreased susceptibility to potassium bromate	25693136
D011441	Propylthiouracil	Propylthiouracil results in increased expression of OGG1 mRNA	24780913
C031280	pyrazole	pyrazole results in increased expression of OGG1 mRNA	17945193
D011791	Quartz	Quartz results in decreased expression of OGG1 mRNA	27917503
D011794	Quercetin	Quercetin promotes the reaction [Hydrogen Peroxide results in increased expression of OGG1 mRNA]	19651184
D011794	Quercetin	Quercetin results in increased expression of OGG1 mRNA	19651184
C004532	quinone	quinone results in decreased expression of OGG1 mRNA	26456483
D017382	Reactive Oxygen Species	Reactive Oxygen Species affects the expression of OGG1 mRNA	25800948
D017382	Reactive Oxygen Species	Reactive Oxygen Species results in increased expression of OGG1 mRNA	29085557
C059514	resveratrol	resveratrol results in increased expression of OGG1 mRNA	22056336
C059514	resveratrol	resveratrol results in increased expression of OGG1 protein	22056336
C059514	resveratrol	resveratrol inhibits the reaction [Estradiol results in decreased expression of OGG1 mRNA]	24894866
C059514	resveratrol	resveratrol inhibits the reaction [Estradiol results in decreased expression of OGG1 protein]	24894866
C059514	resveratrol	resveratrol results in increased expression of OGG1 mRNA	24894866
C059514	resveratrol	resveratrol results in increased expression of OGG1 protein	24894866
C547185	riccardin D	riccardin D results in decreased expression of OGG1 mRNA	24069304
C041376	rosmarinic acid	rosmarinic acid results in increased expression of OGG1 mRNA	18996367
C534628	SCH 23390	[Methamphetamine co-treated with SCH 23390] results in decreased expression of OGG1 mRNA	19564919
D012643	Selenium	[Selenium co-treated with Arsenic] results in increased expression of OGG1 protein	20478284
D012643	Selenium	Selenium results in increased expression of OGG1 protein	20478284
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of OGG1 mRNA	25351596
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of OGG1 protein	23178243
D018030	Silver Compounds	Silver Compounds results in decreased expression of OGG1 mRNA	21925250
D018030	Silver Compounds	Silver Compounds results in decreased expression of OGG1 protein	21925250
D012906	Smoke	Smoke results in increased expression of OGG1 mRNA	20864625
C017947	sodium arsenite	[Zinc deficiency co-treated with sodium arsenite] results in decreased expression of OGG1 mRNA	28837703
C017947	sodium arsenite	sodium arsenite results in decreased expression of and results in decreased activity of OGG1 protein	12359242
C017947	sodium arsenite	sodium arsenite results in decreased expression of OGG1 mRNA	12359242\|2643215
C017947	sodium arsenite	sodium arsenite results in decreased expression of OGG1 protein	26432159
C017947	sodium arsenite	OGG1 gene mutant form results in increased susceptibility to sodium arsenite	26438402
C017947	sodium arsenite	[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which affects the expression of ACTA2 mRNA	26438402
C017947	sodium arsenite	[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which affects the expression of KLF4 mRNA	26438402
C017947	sodium arsenite	[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which affects the expression of NANOG mRNA	26438402
C017947	sodium arsenite	[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which affects the expression of NOTCH2 protein	26438402
C017947	sodium arsenite	[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which affects the expression of POU5F1 protein	26438402
C017947	sodium arsenite	[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which results in decreased expression of MYC protein	26438402
C017947	sodium arsenite	[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which results in increased expression of SOX2 mRNA	26438402
C017947	sodium arsenite	sodium arsenite results in decreased expression of OGG1 mRNA	17558810\|2064370
C017947	sodium arsenite	sodium arsenite results in increased expression of OGG1 mRNA	20643705
C017947	sodium arsenite	sodium arsenite results in decreased expression of OGG1 protein	26432159
C016104	sodium bichromate	OGG1 protein polymorphism results in increased susceptibility to sodium bichromate	15734978
C016104	sodium bichromate	sodium bichromate results in decreased expression of OGG1 mRNA	11756223
C016104	sodium bichromate	sodium bichromate results in decreased expression of OGG1 protein	11756223
C016104	sodium bichromate	sodium bichromate results in increased expression of OGG1 mRNA	22561333
D012999	Soman	Soman results in decreased expression of OGG1 mRNA	19281266
D053260	Soot	Soot results in increased expression of OGG1 mRNA	19165387
D053260	Soot	Soot results in increased expression of OGG1 protein	23178243
D020058	Styrene	OGG1 protein polymorphism affects the susceptibility to Styrene	19563869
D020058	Styrene	Styrene results in increased expression of OGG1 mRNA	21030303
C061133	tamibarotene	tamibarotene results in increased expression of OGG1 mRNA	15498508
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of OGG1 mRNA	21354282
D013852	Thiotepa	OGG1 protein results in decreased susceptibility to Thiotepa	11181913\|1143134
C029390	thymidine glycol	thymidine glycol inhibits the reaction [OGG1 protein results in increased cleavage of 8-oxo-7-hydrodeoxyguanosine]	19193190
C029390	thymidine glycol	thymidine glycol promotes the reaction [OGG1 protein results in increased cleavage of 8-oxo-7-hydrodeoxyguanosine]	19193190
C009495	titanium dioxide	[Cadmium Chloride co-treated with titanium dioxide] results in increased expression of OGG1 mRNA	21671166
D014028	Tobacco Smoke Pollution	"[OGG1 protein polymorphism co-treated with Tobacco Smoke Pollution] affects the abundance of 8-oxo-7,8-dihydrodeoxyguanine"	23376476
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased activity of OGG1 protein	21778470
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of OGG1 mRNA	15289447
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of OGG1 protein	21778470
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in decreased expression of OGG1 mRNA	25729387
D014212	Tretinoin	Tretinoin results in increased expression of OGG1 mRNA	15498508
C052920	trimethylarsine oxide	trimethylarsine oxide results in increased expression of OGG1 mRNA	17481689
D014502	Uranyl Nitrate	Uranyl Nitrate results in increased expression of OGG1 mRNA	26362510
D014527	Uric Acid	NLRP3 gene mutant form inhibits the reaction [Uric Acid results in decreased expression of OGG1 mRNA]	23619996
D014527	Uric Acid	Uric Acid results in decreased expression of OGG1 mRNA	23619996
D014635	Valproic Acid	[Hydralazine co-treated with Valproic Acid] results in increased expression of OGG1 mRNA	17183730
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of OGG1 mRNA	12919962
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of OGG1 mRNA	10426809\|1291996
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of OGG1 protein	27091075
D014750	Vincristine	Vincristine results in decreased expression of OGG1 mRNA	23649840
D024483	Vitamin K 3	OGG1 protein SNP results in increased susceptibility to Vitamin K 3	17651912
D024483	Vitamin K 3	Vitamin K 3 results in increased expression of OGG1 mRNA	23410634
C085514	wogonin	wogonin inhibits the reaction [Etoposide results in decreased expression of OGG1 mRNA]	23872129
D015032	Zinc	[Zinc deficiency co-treated with sodium arsenite] results in decreased expression of OGG1 mRNA	28837703

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0003684	damaged DNA binding	-	IDA	14706345
GO:0004519	endonuclease activity	-	TAS	9223305
GO:0005515	protein binding	-	IPI	15518571
GO:0008017	microtubule binding	-	IEA	-
GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity	-	IBA	21873635
GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity	-	TAS	-
GO:0019104	DNA N-glycosylase activity	-	IBA	21873635
GO:0032357	oxidized purine DNA binding	-	IBA	21873635
GO:0032357	oxidized purine DNA binding	-	IDA	14706345
GO:0034039	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	-	IBA	21873635
GO:0034039	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	-	IEA	-
GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0002526	acute inflammatory response	-	IEA	-
GO:0006284	base-excision repair	-	IBA	21873635
GO:0006284	base-excision repair	-	TAS	9190902
GO:0006285	base-excision repair, AP site formation	-	IBA	21873635
GO:0006355	regulation of transcription, DNA-templated	-	IMP	8621488
GO:0006974	cellular response to DNA damage stimulus	-	IGI	19506022
GO:0006979	response to oxidative stress	-	IDA	17148573
GO:0007004	telomere maintenance via telomerase	-	IBA	21873635
GO:0007568	aging	-	IEA	-
GO:0009314	response to radiation	-	IDA	17148573
GO:0009416	response to light stimulus	-	IEA	-
GO:0032355	response to estradiol	-	IEA	-
GO:0033683	nucleotide-excision repair, DNA incision	-	IDA	19506022
GO:0043066	negative regulation of apoptotic process	-	IEA	-
GO:0045007	depurination	-	TAS	-
GO:0045008	depyrimidination	-	TAS	-
GO:0045471	response to ethanol	-	IEA	-
GO:0051593	response to folic acid	-	IEA	-
GO:0071276	cellular response to cadmium ion	-	IEA	-
GO:1901291	negative regulation of double-strand break repair via single-strand annealing	-	IDA	19506022

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	IBA	21873635
GO:0005634	nucleus	-	IDA	19506022
GO:0005654	nucleoplasm	-	IDA	17148573
GO:0005654	nucleoplasm	-	TAS	-
GO:0005739	mitochondrion	-	IEA	-
GO:0016363	nuclear matrix	-	IDA	17148573
GO:0016607	nuclear speck	-	IDA	17148573
GO:0032991	protein-containing complex	-	IDA	19506022

KEGG ID	KEGG Term
hsa03410	Base excision repair

Reactome ID	Reactome Term	Evidence
R-HSA-110328	Recognition and association of DNA glycosylase with site containing an affected pyrimidine	TAS
R-HSA-110329	Cleavage of the damaged pyrimidine	TAS
R-HSA-110330	Recognition and association of DNA glycosylase with site containing an affected purine	TAS
R-HSA-110331	Cleavage of the damaged purine	TAS
R-HSA-110357	Displacement of DNA glycosylase by APEX1	TAS
R-HSA-5649702	APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	TAS
R-HSA-73884	Base Excision Repair	TAS
R-HSA-73894	DNA Repair	TAS
R-HSA-73927	Depurination	TAS
R-HSA-73928	Depyrimidination	TAS
R-HSA-73929	Base-Excision Repair, AP Site Formation	TAS
R-HSA-73933	Resolution of Abasic Sites (AP sites)	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
22452928	Controlled human wood smoke exposure: oxidative stress, inflammation and microvascular function. (2012 Mar 27)	Forchhammer L	Part Fibre Toxicol
22044660	Association between 8-oxo-7,8-dihydroguanine excretion and risk of lung cancer in a prospective study. (2012 Jan 1)	Loft S	Free Radic Biol Med
12164330	A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung. (2002 May)	Ito H	J Epidemiol
22829015	Novel mutations of OGG1 base excision repair pathway gene in laryngeal cancer patients. (2012 Dec)	Mahjabeen I	Fam Cancer
16381036	Interaction of OGG1 Ser326Cys polymorphism with cigarette smoking in head and neck squamous cell carcinoma. (2006 May)	Hashimoto T	Mol Carcinog
22850545	Selected polymorphisms of base excision repair genes and pancreatic cancer risk in Japanese. (2012)	Nakao M	J Epidemiol
21575478	[Role of heterogeneous nuclear ribonucleoprotein A2/B1 protein in the pathogenesis of non-small cell lung cancer]. (2011 Feb)	Shi Y	Zhonghua Zhong Liu Za Zhi
21986195	Role of OGG1 Ser326Cys polymorphism and 8-oxoguanine DNA damage in risk assessment of squamous cell carcinoma of head and neck in North Indian population. (2011 Dec 24)	Kumar A	Mutat Res
26936466	The impact of detoxifying and repair gene polymorphisms on oxidative stress in ischemic stroke. (2016 Jun)	Orhan G	Neurol Sci
23902537	Oxidative DNA damage in human esophageal cancer: clinicopathological analysis of 8-hydroxydeoxyguanosine and its repair enzyme. (2014 Apr)	Kubo N	Dis Esophagus
25967734	Oxidative DNA damage is involved in cigarette smoke-induced lung injury in rats. (2015 Sep)	Chen Z	Environ Health Prev Med
16366378	Polymorphisms of the human OGG1 gene in laryngeal cancer: implications in radiotherapy response and survival. (2005)	Monteiro E	Rev Laryngol Otol Rhinol (Bord)
18628426	The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis. (2008 Jul)	Li H	Cancer Epidemiol Biomarkers Prev
24175791	Association of DNA base-excision repair XRCC1, OGG1 and APE1 gene polymorphisms with nasopharyngeal carcinoma susceptibility in a Chinese population. (2013)	Li Q	Asian Pac J Cancer Prev
21778470	Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice. (2011 Oct)	La Maestra S	Toxicol Sci
19959686	Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer. (2009 Dec)	Curtin K	Cancer Epidemiol Biomarkers Prev
21622940	Single-nucleotide polymorphisms in DNA repair genes and association with breast cancer risk in the web study. (2011 Aug)	Roberts MR	Carcinogenesis
24924712	[Study on gene-gene, gene-environmental interactions of DNA repair genes related with age-related cataract]. (2014 Apr 22)	Yang M	Zhonghua Yi Xue Za Zhi
25335960	Gene-environment interaction involved in cholangiocarcinoma in the Thai population: polymorphisms of DNA repair genes, smoking and use of alcohol. (2014 Oct 21)	Songserm N	BMJ Open
19428376	GPX1 Pro(198)Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer. (2009 May 12)	Hansen RD	Mutat Res
25089939	Polymorphism of DNA repair genes OGG1, XRCC1, XPD and ERCC6 in bladder cancer in Belarus. (2014 Sep)	Ramaniuk VP	Biomarkers
20593951	Lack of influence of DNA repair gene OGG1 codon 326 polymorphisms of gastric cancer risk in the Kashmir valley. (2010)	Malik MA	Asian Pac J Cancer Prev
16614128	OGG1 polymorphisms and breast cancer risk. (2006 Apr)	Rossner P Jr	Cancer Epidemiol Biomarkers Prev
16364924	Prospective study of 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and the risk of lung cancer. (2006 Jun)	Loft S	Carcinogenesis
12117782	The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. (2002 Jul)	Elahi A	Carcinogenesis
22081374	Reduced expression of DNA repair genes (XRCC1, XPD, and OGG1) in squamous cell carcinoma of head and neck in North India. (2012 Feb)	Kumar A	Tumour Biol
19064361	The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lung cancer susceptibility: a hospital-based case-control study in Turkey. (2008 Dec)	Karahalil B	Arh Hig Rada Toksikol
15654505	Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples. (2005)	Liu Y	J Hum Genet
27026921	Association between OGG1 Ser326Cys polymorphism and risk of upper aero-digestive tract and gastrointestinal cancers: a meta-analysis. (2016)	Das S	Springerplus
15840879	Large-scale investigation of base excision repair genetic polymorphisms and lung cancer risk in a multicenter study. (2005 Apr 20)	Hung RJ	J Natl Cancer Inst
20069464	OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and high at-risk populations of northern India. (2010 Jun)	Upadhyay R	J Gastrointest Cancer
15491645	Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations? (2004 Nov 22)	Aka P	Mutat Res
27583352	The hOGG1 Ser326Cys gene polymorphism and susceptibility for bladder cancer: a meta-analysis. (2016 Sep-Oct)	Wenjuan C	Int Braz J Urol
20718982	Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers. (2010 Aug 18)	El-Zein RA	BMC Cancer
22277767	Polymorphisms of DNA repair pathway genes and cigarette smoking in relation to susceptibility to large artery atherosclerotic stroke among ethnic Chinese in Taiwan. (2012)	Shyu HY	J Atheroscler Thromb
20127182	Associations between GSTM1 and OGG1 Ser326Cys polymorphisms and smoking on chromosomal damage and birth growth in mothers. (2011 Jun)	Karahalil B	Mol Biol Rep
23951112	Genetic variation in the base excision repair pathway, environmental risk factors, and colorectal adenoma risk. (2013)	Corral R	PLoS One
18374480	DNA repair of oxidative DNA damage in human carcinogenesis: potential application for cancer risk assessment and prevention. (2008 Jul 18)	Paz-Elizur T	Cancer Lett
17015267	Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and vegetables in relation to lung cancer. (2006 Aug)	Sorensen M	Free Radic Res
29139108	A 3' untranslated region polymorphism rs2304277 in the DNA repair pathway gene OGG1 is a novel risk modulator for urothelial bladder carcinoma. (2018 Mar)	Ahmed T	Ann Hum Genet
20056743	The role of oxidative DNA damage, DNA repair, GSTM1, SOD2 and OGG1 polymorphisms in individual susceptibility to Barrett's esophagus. (2010 Mar)	Kadioglu E	Toxicol Ind Health
19815090	Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population? (2009 Nov-Dec)	Gangwar R	Mutat Res
17922186	Polymorphisms in three base excision repair genes and breast cancer risk in Thai women. (2008 Sep)	Sangrajrang S	Breast Cancer Res Treat
17178863	Reduced repair of the oxidative 8-oxoguanine DNA damage and risk of head and neck cancer. (2006 Dec 15)	Paz-Elizur T	Cancer Res
11927502	Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. (2002 Apr)	Le Marchand L	Cancer Epidemiol Biomarkers Prev
26562193	The impact of detoxifying and repair gene polymorphisms and the levels of serum ROS in the susceptibility to multiple sclerosis. (2015 Dec)	Karahalil B	Clin Neurol Neurosurg
21426660	[Mutational analysis of hOGG1 gene promoter in patients with non-small cell lung cancer]. (2011 Mar)	Liu X	Zhongguo Fei Ai Za Zhi
10744126	hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. (1999 Aug)	Sugimura H	Cancer Epidemiol Biomarkers Prev
18155253	OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study. (2008 Mar 1)	Hatt L	Mutat Res
20870921	Bladder Cancer Working Group report. (2010 Sep)	Kakehi Y	Jpn J Clin Oncol
19963114	Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women. (2009 Dec)	Klinchid J	Cancer Genet Cytogenet
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