Gene: OLR1

4973
CLEC8A|LOX1|LOXIN|SCARE1|SLOX1
oxidized low density lipoprotein receptor 1
protein-coding
12p13.2
Ensembl:ENSG00000173391 MIM:602601 Vega:OTTHUMG00000168527 UniprotKB:P78380
NG_016743.1
PubMed
0   ANCO-SNPs
ND
7   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.438e-2 (AD)  8.607e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GPR1830.844
PLEK0.833
C3AR10.828
ITGAX0.821
LILRB40.82
B3GNT50.805
SAMSN10.8
C5AR10.799
PTPN60.79
RGS10.787

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF835-0.268
NLGN4Y-0.245
KNCN-0.242
MARCH4-0.24
TEX38-0.24
RPS4Y1-0.24
KCNG1-0.239
GPR148-0.239
ADRA2C-0.239
WNT7A-0.238

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0364231-aminomethylphosphonic acid[Herbicides co-treated with 1-aminomethylphosphonic acid] results in decreased expression of OLR1 mRNA20566314
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of OLR1 mRNA28329830
C0512461-methylanthraceneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of OLR1 mRNA]28329830
C4001841-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of OLR1 mRNA16386258
C0473683-methylquercetin3-methylquercetin inhibits the reaction [Lipids results in increased expression of OLR1]16891912
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased expression of OLR1 mRNA"25912373
C0022024-oxoretinoic acid4-oxoretinoic acid results in increased expression of OLR1 mRNA17034753
C0418194-oxoretinol4-oxoretinol results in increased expression of OLR1 mRNA17034753
D000082AcetaminophenAcetaminophen affects the expression of OLR1 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA]17585979
C056165acetovanilloneacetovanillone inhibits the reaction [Glucose results in increased expression of OLR1 mRNA]19878672
D000111AcetylcysteineAcetylcysteine inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein]24145059
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]16055083
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]16055083
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]16055083
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein]16055083
D000447AldehydesAldehydes results in increased expression of OLR1 mRNA25014914
D000450AldosteroneAldosterone results in increased expression of OLR1 mRNA20508287
D000450AldosteroneAldosterone results in increased expression of OLR1 protein20508287
D000450AldosteroneSpironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 mRNA]20508287
D000450AldosteroneSpironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 protein]20508287
C103303alitretinoinalitretinoin results in increased expression of OLR1 mRNA17034753
C068073Am 580Am 580 results in increased expression of OLR1 mRNA16982809
D017311AmlodipineAmlodipine inhibits the reaction [AGT results in increased expression of OLR1 mRNA]21376258
D017311AmlodipineAmlodipine inhibits the reaction [AGT results in increased expression of OLR1 protein]21376258
D000643Ammonium ChlorideAmmonium Chloride affects the expression of OLR1 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of OLR1 mRNA"22863853
D000936Antigen-Antibody ComplexAntigen-Antibody Complex results in increased expression of OLR1 mRNA25451590
D000936Antigen-Antibody Complexshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of OLR1 mRNA]25451590
C004984apocarotenalapocarotenal results in increased expression of OLR1 mRNA17034753
D034341Aristolochic AcidsAristolochic Acids results in increased expression of OLR1 mRNA21834575
C006632arsenic trioxidearsenic trioxide results in decreased expression of OLR1 mRNA19128835
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of OLR1 mRNA"25757056
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of OLR1 mRNA"23917077
D001205Ascorbic Acid[Quercetin co-treated with Ascorbic Acid] results in increased expression of OLR1 mRNA17639512
D019207beta Carotenebeta Carotene results in increased expression of OLR1 mRNA17034753
D004958EstradiolEstradiol affects the expression of OLR1 mRNA22574217
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of OLR1 mRNA25912373
C006780bisphenol Abisphenol A results in increased expression of OLR1 mRNA25912373
C006780bisphenol Abisphenol A results in increased expression of OLR1 mRNA25181051
C018475butyraldehydebutyraldehyde results in increased expression of OLR1 mRNA26079696
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein]24145059
C459604candoxincandoxin results in decreased expression of OLR1 mRNA16309724
C043211carvedilolcarvedilol inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]16055083
C043211carvedilolcarvedilol inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]16055083
C043211carvedilolcarvedilol inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]16055083
C043211carvedilolcarvedilol inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein]16055083
D002784Cholesterol[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 mRNA25833014
D002784Cholesterol[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 protein25833014
D002784Cholesterolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 mRNA]25833014
D002784Cholesterolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 protein]25833014
D002857ChromiumChromium results in increased expression of OLR1 mRNA21437242
D002857Chromium[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 mRNA]18622720
D002857Chromium[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 protein]18622720
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA]17585979
C018021cobaltous chloridecobaltous chloride results in decreased expression of OLR1 mRNA19376846
D003300Copper[Copper co-treated with Dietary Sucrose] results in increased expression of OLR1 mRNA26033743
D003300CopperCopper deficiency results in increased expression of OLR1 mRNA26033743
D003471CuprizoneCuprizone results in increased expression of OLR1 mRNA26577399|2752363
D003474CurcuminCurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]23386263
D003561CytarabineCytarabine results in decreased expression of OLR1 mRNA21198554
C014347decitabinedecitabine inhibits the reaction [Smoke results in decreased expression of OLR1 mRNA]21095227
D003676DeferoxamineDeferoxamine results in decreased expression of OLR1 protein24170104
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of OLR1 mRNA27634381
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of OLR1 protein27634381
D003687DehydroepiandrosteroneMetformin affects the reaction [Dehydroepiandrosterone results in increased expression of OLR1 protein]27634381
D003687DehydroepiandrosteroneMetformin inhibits the reaction [Dehydroepiandrosterone results in increased expression of OLR1 mRNA]27634381
D003687DehydroepiandrosteroneQuercetin affects the reaction [Dehydroepiandrosterone results in increased expression of OLR1 protein]27634381
D003687DehydroepiandrosteroneQuercetin inhibits the reaction [Dehydroepiandrosterone results in increased expression of OLR1 mRNA]27634381
C050229demethoxycurcumindemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]23386263
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of OLR1 mRNA28962523
D004041Dietary FatsDietary Fats results in increased expression of OLR1 mRNA18622720
D004041Dietary FatsDietary Fats results in increased expression of OLR1 protein18622720
D004041Dietary Fats[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 mRNA]18622720
D004041Dietary Fats[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 protein]18622720
D019422Dietary Sucrose[Copper co-treated with Dietary Sucrose] results in increased expression of OLR1 mRNA26033743
D019422Dietary SucroseDietary Sucrose results in increased expression of OLR1 mRNA26033743
D002117CalcitriolCalcitriol results in decreased expression of OLR1 mRNA16002434
D004110DiltiazemDiltiazem inhibits the reaction [[Glucose results in increased expression of OLR1 protein] which affects the activity of CASP3 protein]20973294
D004317DoxorubicinAcetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]16055083
D004317DoxorubicinAcetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]16055083
D004317Doxorubicincarvedilol inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]16055083
D004317Doxorubicincarvedilol inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]16055083
D004317DoxorubicinDoxorubicin results in increased expression of OLR1 mRNA16055083
D004317DoxorubicinDoxorubicin results in increased expression of OLR1 protein16055083
D004317DoxorubicinOLR1 protein results in increased susceptibility to Doxorubicin16055083
D004317DoxorubicinRazoxane inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]16055083
D004317DoxorubicinRazoxane inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]16055083
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Lipids results in increased expression of OLR1]"16891912
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of OLR1 mRNA22079256
D004875Ergosterol[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 mRNA25833014
D004875Ergosterol[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 protein25833014
D004875Ergosterolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 mRNA]25833014
D004875Ergosterolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 protein]25833014
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of OLR1 mRNA28329830
C007738fluorantheneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of OLR1 mRNA]28329830
C069837fullerene C60fullerene C60 results in increased expression of OLR1 mRNA19167457
C039281furanfuran results in increased expression of OLR1 mRNA27387713
D005947Glucoseacetovanillone inhibits the reaction [Glucose results in increased expression of OLR1 mRNA]19878672
D005947GlucoseGlucose results in increased expression of OLR1 mRNA19878672
D005947GlucoseDiltiazem inhibits the reaction [[Glucose results in increased expression of OLR1 protein] which affects the activity of CASP3 protein]20973294
D005947GlucoseGlucose results in increased expression of OLR1 protein20973294
D005947Glucose[Glucose results in increased expression of OLR1 protein] which affects the activity of CASP3 protein20973294
D006540Herbicides[Herbicides co-treated with 1-aminomethylphosphonic acid] results in decreased expression of OLR1 mRNA20566314
D006861Hydrogen PeroxideAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]16055083
D006861Hydrogen PeroxideAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein]16055083
D006861Hydrogen Peroxidecarvedilol inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]16055083
D006861Hydrogen Peroxidecarvedilol inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein]16055083
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of OLR1 mRNA16055083
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of OLR1 protein16055083
D006861Hydrogen PeroxideRazoxane inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]16055083
D006861Hydrogen PeroxideRazoxane inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein]16055083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of OLR1 mRNA25613284
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of OLR1 mRNA26752646
C029310lardlard results in increased expression of OLR1 mRNA26115784
D008055Lipids3-methylquercetin inhibits the reaction [Lipids results in increased expression of OLR1]16891912
D008055Lipids"Drugs, Chinese Herbal inhibits the reaction [Lipids results in increased expression of OLR1]"16891912
D008055LipidsQuercetin inhibits the reaction [Lipids results in increased expression of OLR1]16891912
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of OLR1 mRNA22124178
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of OLR1 protein22124178
D008070Lipopolysaccharidestelmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 mRNA]22124178
D008070Lipopolysaccharidestelmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 protein]22124178
D008687MetforminMetformin affects the reaction [Dehydroepiandrosterone results in increased expression of OLR1 protein]27634381
D008687MetforminMetformin inhibits the reaction [Dehydroepiandrosterone results in increased expression of OLR1 mRNA]27634381
C054634methyllycaconitinemethyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 mRNA]28202387
C054634methyllycaconitinemethyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 protein]28202387
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of OLR1 mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of OLR1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of OLR1 mRNA"25554681
D009525Niacin[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 mRNA]18622720
D009525Niacin[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 protein]18622720
C017557nickel subsulfidenickel subsulfide results in increased expression of OLR1 mRNA21086188
D009543NifedipineNifedipine results in decreased expression of OLR1 mRNA12072588
D010126Ozone[Ozone co-treated with Vehicle Emissions] results in increased expression of OLR1 protein20980218
D010126OzoneOzone results in increased expression of OLR1 mRNA20980218
D010126OzoneOzone results in increased expression of OLR1 protein20980218
C046012pentanalpentanal results in increased expression of OLR1 mRNA26079696
D010972Platelet Activating FactorPlatelet Activating Factor results in increased expression of OLR1 mRNA16386258
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of OLR1 mRNA27989595
D059808PolyphenolsPolyphenols results in decreased expression of OLR1 mRNA16293270
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of OLR1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of OLR1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of OLR1 mRNA22714537
D017035PravastatinPravastatin results in increased expression of OLR1 mRNA27225895
D011374ProgesteroneProgesterone results in decreased expression of OLR1 mRNA20726854
C005556propionaldehydepropionaldehyde results in increased expression of OLR1 mRNA26079696
D011794Quercetin[Quercetin co-treated with Ascorbic Acid] results in increased expression of OLR1 mRNA17639512
D011794QuercetinQuercetin inhibits the reaction [Lipids results in increased expression of OLR1]16891912
D011794QuercetinQuercetin affects the expression of OLR1 mRNA18178720
D011794QuercetinQuercetin affects the reaction [Dehydroepiandrosterone results in increased expression of OLR1 protein]27634381
D011794QuercetinQuercetin inhibits the reaction [Dehydroepiandrosterone results in increased expression of OLR1 mRNA]27634381
D011929RazoxaneRazoxane inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]16055083
D011929RazoxaneRazoxane inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]16055083
D011929RazoxaneRazoxane inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]16055083
D011929RazoxaneRazoxane inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein]16055083
C059514resveratrolOLR1 protein results in decreased susceptibility to resveratrol20940732
C059514resveratrolresveratrol results in decreased expression of OLR1 protein24170104
C059514resveratrolOLR1 protein affects the susceptibility to resveratrol20940732
C059514resveratrolresveratrol results in decreased expression of OLR1 mRNA20940732
C059514resveratrolresveratrol results in decreased expression of OLR1 protein20940732
C059514resveratrolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 mRNA]25833014
C059514resveratrolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 protein]25833014
C089730rosiglitazonerosiglitazone results in increased expression of OLR1 mRNA16982809
D012524SarinSarin results in decreased expression of OLR1 mRNA19522546
D012524SarinSarin results in increased expression of OLR1 mRNA19522546
C093642SB 203580SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of OLR1 mRNA]28329830
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of OLR1 mRNA"24160326
C016101shikoninshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of OLR1 mRNA]25451590
D012822Silicon DioxideSilicon Dioxide results in decreased expression of OLR1 mRNA19073995
D012822Silicon DioxideSilicon Dioxide results in increased expression of OLR1 mRNA19073995
D012834SilverSilver results in increased expression of OLR1 mRNA28959546
D019821SimvastatinSimvastatin results in decreased expression of OLR119801495
D019821SimvastatinSimvastatin results in decreased expression of OLR1 mRNA16414398
D020123SirolimusSirolimus affects the expression of OLR1 protein17016853
D012906Smokedecitabine inhibits the reaction [Smoke results in decreased expression of OLR1 mRNA]21095227
D012906SmokeSmoke results in decreased expression of OLR1 mRNA21095227
C017947sodium arseniteAcetylcysteine inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein]24145059
C017947sodium arsenitecaffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein]24145059
C017947sodium arsenitesodium arsenite results in increased expression of OLR1 mRNA24145059
C017947sodium arsenitesodium arsenite results in increased expression of OLR1 protein24145059
D012969Sodium FluorideSodium Fluoride results in decreased expression of OLR1 mRNA27257137
D012999SomanSoman results in increased expression of OLR1 mRNA19281266
D053260SootSoot results in increased expression of OLR1 mRNA22461453
D013148SpironolactoneSpironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 mRNA]20508287
D013148SpironolactoneSpironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 protein]20508287
C075117squalestatin 1squalestatin 1 affects the expression of OLR1 mRNA27225895
C075117squalestatin 1squalestatin 1 results in decreased expression of OLR1 mRNA27225895
C021751tanshinonetanshinone results in decreased expression of OLR1 mRNA22677363
C021751tanshinonetanshinone results in decreased expression of OLR1 protein22677363
C084178telmisartantelmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 mRNA]22124178
C084178telmisartantelmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 protein]22124178
D013755Tetradecanoylphorbol AcetateCurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]23386263
D013755Tetradecanoylphorbol Acetatedemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]23386263
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA23386263
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of OLR1 mRNA25613284
C009495titanium dioxidetitanium dioxide results in increased expression of OLR1 protein22352400
C009495titanium dioxidetitanium dioxide results in increased expression of OLR1 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of OLR1 mRNA20133372
C513941tongxinluotongxinluo results in decreased expression of OLR119801495
D014212TretinoinTretinoin results in increased expression of OLR1 mRNA17034753|2383079
D014638VanadatesVanadates results in decreased expression of OLR1 mRNA22714537
D000068580Vareniclinemethyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 mRNA]28202387
D000068580Vareniclinemethyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 protein]28202387
D000068580VareniclineVarenicline results in increased expression of OLR1 mRNA28202387
D000068580VareniclineVarenicline results in increased expression of OLR1 protein28202387
D001335Vehicle EmissionsVehicle Emissions results in increased expression of OLR1 protein21493736
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of OLR1 gene25560391
D001335Vehicle Emissions[Ozone co-treated with Vehicle Emissions] results in increased expression of OLR1 protein20980218
D001335Vehicle EmissionsVehicle Emissions results in increased expression of OLR1 mRNA20980218
D014801Vitamin AVitamin A results in increased expression of OLR1 mRNA17034753
C009687wortmanninwortmannin affects the expression of OLR1 protein19150883
C088658zoledronic acidzoledronic acid results in increased expression of OLR1 protein28871336

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI24846140  
GO:0030246carbohydrate binding-IEA-  
GO:0042802identical protein binding-IPI15939022  19664054  
GO ID GO Term Qualifier Evidence PubMed
GO:0006508proteolysis-TAS9052782  
GO:0006954inflammatory response-IEA-  
GO:0007155cell adhesion-IEA-  
GO:0008015blood circulation-TAS9052782  
GO:0043312neutrophil degranulation-TAS-  
GO:0050900leukocyte migration-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IEA-  
GO:0005654nucleoplasm-IDA-  
GO:0005886plasma membrane-IDA-  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-TAS9052782  
GO:0016020membrane-TAS9052782  
GO:0035579specific granule membrane-TAS-  
GO:0043231intracellular membrane-bounded organelle-IDA-  
GO:0043235receptor complex-IDA23382219  
GO:0045121membrane raft-IEA-  
GO:0070821tertiary granule membrane-TAS-  
KEGG ID KEGG Term
hsa03320PPAR signaling pathway
hsa04145Phagosome
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-202733Cell surface interactions at the vascular wallTAS
R-HSA-6798695Neutrophil degranulationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20023241Is LOX-1 K167N polymorphism protective for coronary artery disease? (2009 Nov-Dec)Kurnaz OIn Vivo
21904818LOX-1/LOXIN: the yin/yang of atheroscleorosis. (2011 Oct)Mango RCardiovasc Drugs Ther
24743687Association of LOXIN, a new functional splicing isoform of the OLR1 gene, with severity and prognostic localization of critical coronary artery stenoses. (2014 May)Cappelletti AJ Cardiovasc Med (Hagerstown)
21257822A candidate gene study revealed sex-specific association between the OLR1 gene and carotid plaque. (2011 Mar)Wang LStroke
22371740Genetic variability and the risk of myocardial infarction in Poles under 45 years of age. (2010 Apr 30)Sakowicz AArch Med Sci
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