Gene: OR3A2

4995
OLFRA04|OR17-14|OR17-228|OR228
olfactory receptor family 3 subfamily A member 2
protein-coding
17p13.3
Ensembl:ENSG00000221882 Vega:OTTHUMG00000177667 UniprotKB:P47893
NC_000017.11
SNP Mapped
0   ANCO-SNPs
CD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.474e-1 (AD)  4.964e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF7370.512
ARSG0.506
RNPC30.501
MYO9A0.495
SLC12A60.494
RALGPS20.491
TXNDC160.491
ANAPC10.488
SPICE10.485
PIAS10.485

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PPP1R14B-0.311
VAX2-0.31
S100A1-0.305
RBP1-0.302
PDZK1IP1-0.297
LYPD1-0.283
BCL7C-0.282
PRRX2-0.281
AQP5-0.274
S100A14-0.273

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of OR3A2 mRNA"17331233

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004888transmembrane signaling receptor activity-IBA21873635  
GO:0004930G-protein coupled receptor activity-IEA-  
GO:0038023signaling receptor activity-TAS8921386  
GO ID GO Term Qualifier Evidence PubMed
GO:0007165signal transduction-TAS8921386  
GO:0007186G-protein coupled receptor signaling pathway-IBA21873635  
GO:0007606sensory perception of chemical stimulus-TAS8921386  
GO:0050911detection of chemical stimulus involved in sensory perception of smell-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-TAS8921386  
KEGG ID KEGG Term
hsa04740Olfactory transduction
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-381753Olfactory Signaling PathwayTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-418555G alpha (s) signalling eventsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal