Gene: OVGP1

5016
CHIT5|EGP|MUC9|OGP
oviductal glycoprotein 1
protein-coding
1p13.2
Ensembl:ENSG00000085465 MIM:603578 Vega:OTTHUMG00000011746 UniprotKB:Q12889
NG_052675.1
PubMed
0   ANCO-SNPs
ND|AD
1   
2.160e-1 (AD)  7.715e-1 (ND)   (Frontal_Cortex)
3.074e-1 (AD)  3.800e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TFAP2E0.86
AMY2B0.86
GOLGA8A0.851
TTC21A0.833
SEC31B0.816
NR2C10.812
EXOSC100.808
ABCA100.808
ZNF2510.806
LY6G5B0.806

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TSPAN12-0.362
CCDC102A-0.357
LYPD1-0.332
OR4F5-0.325
HIST1H2AG-0.323
GDF11-0.313
OR4F29-0.31
FOXJ1-0.307
WDR38-0.301
LHFPL1-0.296

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of OVGP1 mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of OVGP1 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of OVGP1 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of OVGP1 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of OVGP1 mRNA"25510870
D000082AcetaminophenAcetaminophen affects the expression of OVGP1 mRNA17562736
D004958EstradiolEstradiol results in increased expression of OVGP1 protein15501902
D004958EstradiolProgesterone inhibits the reaction [Estradiol results in increased expression of OVGP1 protein]15501902
D003024ClozapineClozapine results in increased expression of OVGP1 mRNA17346280
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of OVGP1 mRNA28962523
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of OVGP1 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of OVGP1 mRNA27392435
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of OVGP1 mRNA22079256
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of OVGP1 mRNA22634610
D006997Hypochlorous AcidHypochlorous Acid results in decreased expression of OVGP1 mRNA19376150
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of OVGP1 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of OVGP1 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of OVGP1 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of OVGP1 mRNA27432991
C045463leflunomideleflunomide results in increased expression of OVGP1 mRNA28988120
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of OVGP1 mRNA"25510870
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of OVGP1 mRNA19710929
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of OVGP1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of OVGP1 mRNA22079256
D011192Potassium DichromatePotassium Dichromate results in decreased expression of OVGP1 mRNA23608068
D011374ProgesteroneProgesterone inhibits the reaction [Estradiol results in increased expression of OVGP1 protein]15501902
D011374ProgesteroneProgesterone affects the expression of OVGP1 mRNA17251523
D012643Selenium[Selenium co-treated with Vitamin E] results in decreased expression of OVGP1 mRNA19244175
D012643SeleniumSelenium results in increased expression of OVGP1 mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of OVGP1 mRNA25895662
D012906SmokeSmoke affects the expression of OVGP1 mRNA23693141
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of OVGP1 mRNA21570461
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of OVGP1 mRNA25613284
D014415TunicamycinTunicamycin results in increased expression of OVGP1 mRNA22378314
D014635Valproic AcidValproic Acid results in decreased expression of OVGP1 mRNA29154799
D014635Valproic AcidValproic Acid results in decreased methylation of OVGP1 gene29154799
D014635Valproic AcidValproic Acid results in decreased expression of OVGP1 mRNA24896083
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of OVGP1 gene25560391
D014810Vitamin E[Selenium co-treated with Vitamin E] results in decreased expression of OVGP1 mRNA19244175
D014810Vitamin EVitamin E results in decreased expression of OVGP1 mRNA19244175
C088658zoledronic acidzoledronic acid results in increased expression of OVGP1 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004568chitinase activity-IBA21873635  
GO:0008061chitin binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005975carbohydrate metabolic process-IEA-  
GO:0006032chitin catabolic process-IBA21873635  
GO:0007339binding of sperm to zona pellucida-TAS-  
GO:0007565female pregnancy-TAS9341614  
GO:2000360negative regulation of binding of sperm to zona pellucida-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IBA21873635  
GO:0005737cytoplasm-IBA21873635  
GO:0005829cytosol-TAS-  
GO:0030133transport vesicle-IEA-  
GO:0035805egg coat-IEA-  
GO:0098595perivitelline space-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1187000FertilizationTAS
R-HSA-1300644Interaction With The Zona PellucidaTAS
R-HSA-1474165ReproductionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27222041A proteomic signature of ovarian cancer tumor fluid identified by highthroughput and verified by targeted proteomics. (2016 Aug 11)Poersch AJ Proteomics