C026486 | 1,2,5,6-dibenzanthracene | "1,2,5,6-dibenzanthracene results in increased expression of P2RX7 mRNA" | 26377693 |
C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in increased expression of P2RX7 mRNA" | 23146750 |
C017199 | 2',3'-dialdehyde ATP | "2',3'-dialdehyde ATP binds to and results in decreased activity of P2RX7 protein" | 15258577|1591464 |
C010914 | 2,4-diaminotoluene | "2,4-diaminotoluene results in decreased expression of P2RX7 mRNA" | 20713471 |
C523668 | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | "3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein]" | 27466191 |
C523668 | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | "3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]" | 21638035 |
C523668 | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | "3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine results in decreased activity of P2RX7 protein" | 27466191 |
C523668 | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | "3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine binds to and results in decreased activity of P2RX7 protein" | 21638035 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK1 protein | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK3 protein | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL1B protein | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL2 protein | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | Berberine affects the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | KN 62 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK1 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK3 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL2 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | protoberberine analog inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK1 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK3 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL1B protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL2 protein] | 21320518 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | "3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein]" | 27466191 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein | 27466191 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased expression of P2RX7 protein | 26522449 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | azetidine analog inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased expression of P2RX7 protein] | 26522449 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | P2RX7 gene mutant form results in decreased susceptibility to 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | 17728465|2410173 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | P2RX7 protein affects the susceptibility to 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | 12873706 |
C033901 | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate binds to and results in increased activity of P2RX7 protein | 15914640|1772846 |
D000082 | Acetaminophen | Acetaminophen results in increased expression of P2RX7 mRNA | 29067470 |
C022571 | adenosine 5'-O-(3-thiotriphosphate) | P2RX7 protein affects the susceptibility to adenosine 5'-O-(3-thiotriphosphate) | 12873706 |
D000255 | Adenosine Triphosphate | [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA | 24149798 |
D000255 | Adenosine Triphosphate | [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein | 24149798 |
D000255 | Adenosine Triphosphate | Adenosine Triphosphate results in increased activity of P2RX7 protein | 19023039 |
D000255 | Adenosine Triphosphate | P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein] | 11003599 |
D000255 | Adenosine Triphosphate | P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium] | 11003599 |
D000255 | Adenosine Triphosphate | resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA] | 24149798 |
D000255 | Adenosine Triphosphate | resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein] | 24149798 |
D000255 | Adenosine Triphosphate | "3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]" | 21638035 |
D000255 | Adenosine Triphosphate | Adenosine Triphosphate results in increased activity of P2RX7 protein | 19023039|2163803 |
D000255 | Adenosine Triphosphate | Adenosine Triphosphate results in increased expression of P2RX7 protein | 26522449 |
D000255 | Adenosine Triphosphate | azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of P2RX7 protein] | 26522449 |
D000255 | Adenosine Triphosphate | coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein] | 21638035 |
D000255 | Adenosine Triphosphate | P2RX7 gene mutant form results in decreased susceptibility to Adenosine Triphosphate | 17728465|2410173 |
D000255 | Adenosine Triphosphate | P2RX7 protein results in increased susceptibility to Adenosine Triphosphate | 23565201 |
D000255 | Adenosine Triphosphate | "pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]" | 21638035 |
D000255 | Adenosine Triphosphate | Adenosine Triphosphate results in increased activity of P2RX7 protein | 19023039 |
D000255 | Adenosine Triphosphate | Adenosine Triphosphate results in increased activity of P2RX7 protein | 21320518 |
D000255 | Adenosine Triphosphate | [Adenosine Triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK1 protein | 21320518 |
D000255 | Adenosine Triphosphate | [Adenosine Triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK3 protein | 21320518 |
D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased expression of P2RX7 mRNA | 27153756 |
D000395 | Air Pollutants, Occupational | "Air Pollutants, Occupational results in decreased expression of P2RX7 mRNA" | 23195993 |
D000517 | alpha-Chlorohydrin | alpha-Chlorohydrin affects the expression of P2RX7 mRNA | 28522335 |
D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of P2RX7 mRNA | 16483693 |
D018501 | Antirheumatic Agents | Antirheumatic Agents results in decreased expression of P2RX7 mRNA | 24449571 |
D047310 | Apigenin | Apigenin inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein] | 25935278 |
C082735 | azetidine | azetidine analog inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased expression of P2RX7 protein] | 26522449 |
C082735 | azetidine | azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of P2RX7 protein] | 26522449 |
D001464 | Barium | P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium] | 11003599 |
C030935 | benz(a)anthracene | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | 27858113 |
D001554 | Benzene | Benzene results in increased expression of P2RX7 mRNA | 19162166 |
C006703 | benzo(b)fluoranthene | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | 27858113 |
C006703 | benzo(b)fluoranthene | benzo(b)fluoranthene results in increased expression of P2RX7 mRNA | 26377693 |
C022921 | benzo(k)fluoranthene | benzo(k)fluoranthene results in increased expression of P2RX7 mRNA | 26377693 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of P2RX7 mRNA | 20064835 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of P2RX7 protein | 26657896 |
D001564 | Benzo(a)pyrene | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | 27858113 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of P2RX7 mRNA | 20713471 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of P2RX7 mRNA | 19770486|2156981 |
D001599 | Berberine | Berberine affects the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] | 21320518 |
C006780 | bisphenol A | bisphenol A results in decreased expression of P2RX7 mRNA | 25181051 |
D002118 | Calcium | [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium | 21320518 |
D002118 | Calcium | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] | 21320518 |
D002118 | Calcium | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] | 21320518 |
D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of P2RX7 mRNA | 17484886 |
D002351 | Carrageenan | "[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Carrageenan" | 16982702 |
C054133 | casticin | casticin results in increased expression of P2RX7 mRNA | 28444820 |
C562356 | CE 224,535 | "CE 224,535 binds to and results in decreased activity of P2RX7 protein" | 21320518 |
D002794 | Choline | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of P2RX7 mRNA | 20938992 |
C031180 | chrysene | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | 27858113 |
D003033 | Coal Tar | Coal Tar results in increased expression of P2RX7 mRNA | 27858113 |
C004692 | coomassie Brilliant Blue | coomassie Brilliant Blue binds to and results in decreased activity of P2RX7 protein | 23583883 |
C004692 | coomassie Brilliant Blue | coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein] | 21638035 |
C004692 | coomassie Brilliant Blue | coomassie Brilliant Blue results in decreased activity of P2RX7 protein | 27466191 |
C004692 | coomassie Brilliant Blue | coomassie Brilliant Blue binds to and results in decreased activity of P2RX7 protein | 15914640|1966662 |
D016572 | Cyclosporine | Cyclosporine results in increased expression of P2RX7 mRNA | 20106945 |
D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of P2RX7 mRNA | 21266533 |
D002945 | Cisplatin | Cisplatin results in increased expression of P2RX7 mRNA | 21151649 |
D002945 | Cisplatin | Cisplatin results in increased expression of P2RX7 protein | 25308879 |
D004008 | Diclofenac | Diclofenac results in increased expression of P2RX7 mRNA | 26934552 |
D004008 | Diclofenac | Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein] | 25935278 |
D004026 | Dieldrin | Dieldrin results in increased expression of P2RX7 mRNA | 23041725 |
C014476 | diethyl maleate | diethyl maleate results in decreased expression of P2RX7 mRNA | 21161181 |
D004052 | Diethylnitrosamine | Diethylnitrosamine results in increased expression of P2RX7 mRNA | 17942915|2453584 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of P2RX7 mRNA] | 17942915 |
D004317 | Doxorubicin | Doxorubicin affects the expression of P2RX7 | 17402594 |
D004837 | Epinephrine | Epinephrine results in decreased activity of P2RX7 protein | 15459114 |
D004996 | Ethidium | P2RX7 gene polymorphism results in decreased transport of Ethidium | 16263709 |
D004996 | Ethidium | P2RX7 protein results in increased transport of Ethidium | 16263709 |
D005047 | Etoposide | Etoposide results in increased expression of P2RX7 mRNA | 25270620 |
D005492 | Folic Acid | Folic Acid results in decreased expression of P2RX7 mRNA | 25006883 |
D005492 | Folic Acid | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of P2RX7 mRNA | 20938992 |
D005620 | Freund's Adjuvant | Apigenin inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein] | 25935278 |
D005620 | Freund's Adjuvant | Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein] | 25935278 |
D005620 | Freund's Adjuvant | Freund's Adjuvant results in increased expression of P2RX7 protein | 25935278 |
D005620 | Freund's Adjuvant | "[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Freund's Adjuvant" | 16982702 |
C039281 | furan | furan results in decreased expression of P2RX7 mRNA | 25539665|2738771 |
C546771 | gardiquimod | gardiquimod results in increased expression of P2RX7 mRNA | 28003376 |
C546771 | gardiquimod | Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of P2RX7 mRNA] | 28003376 |
D019833 | Genistein | Genistein results in increased expression of P2RX7 mRNA | 22553218 |
D005947 | Glucose | Glucose results in increased expression of P2RX7 mRNA | 21832250 |
D017313 | Fenretinide | Fenretinide results in increased expression of P2RX7 mRNA | 28973697 |
D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of P2RX7 mRNA | 25613284 |
D007501 | Iron | Iron deficiency results in increased expression of P2RX7 mRNA | 20368581 |
D007657 | Ketone Bodies | Ketone Bodies results in decreased expression of P2RX7 mRNA | 16807920 |
C063302 | KN 62 | KN 62 analog binds to and results in decreased activity of P2RX7 protein | 12672232 |
C063302 | KN 62 | KN 62 binds to and results in decreased activity of P2RX7 protein | 12672232 |
C063302 | KN 62 | KN 62 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] | 21320518 |
C063302 | KN 62 | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] | 21320518 |
C063302 | KN 62 | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK1 protein] | 21320518 |
C063302 | KN 62 | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK3 protein] | 21320518 |
C063302 | KN 62 | KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL2 protein] | 21320518 |
C063302 | KN 62 | KN 62 binds to and results in decreased activity of P2RX7 protein | 21320518 |
C008261 | lead acetate | lead acetate results in increased expression of P2RX7 mRNA | 22641619|2647846 |
C008261 | lead acetate | lead acetate results in increased expression of P2RX7 protein | 20932874|2647846 |
D008070 | Lipopolysaccharides | [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA | 24149798 |
D008070 | Lipopolysaccharides | [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein | 24149798 |
D008070 | Lipopolysaccharides | resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA] | 24149798 |
D008070 | Lipopolysaccharides | resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein] | 24149798 |
D008070 | Lipopolysaccharides | Lipopolysaccharides results in decreased expression of P2RX7 mRNA alternative form | 26068648 |
D008555 | Melitten | Melitten results in increased activity of P2RX7 protein | 22613720 |
D008555 | Melitten | P2RX7 protein results in increased susceptibility to Melitten | 22613720 |
D008627 | Mercuric Chloride | Mercuric Chloride results in decreased expression of P2RX7 mRNA | 23872137 |
D008715 | Methionine | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of P2RX7 mRNA | 20938992 |
D008748 | Methylcholanthrene | [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA | 23519560 |
D008748 | Methylcholanthrene | Methylcholanthrene results in decreased expression of P2RX7 mRNA | 20713471 |
D018817 | N-Methyl-3,4-methylenedioxyamphetamine | "N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of P2RX7 mRNA" | 19285098 |
C059539 | midostaurin | midostaurin results in decreased expression of P2RX7 mRNA | 20980353 |
C515928 | (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) | "(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein" | 16982702 |
C515928 | (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) | "[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased secretion of IL1B protein" | 16982702 |
C515928 | (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) | "[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Carrageenan" | 16982702 |
C515928 | (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) | "[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Freund's Adjuvant" | 16982702 |
C515928 | (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) | "[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Vincristine" | 16982702 |
D019829 | Nevirapine | Nevirapine results in decreased expression of P2RX7 mRNA | 23947594 |
D009532 | Nickel | Nickel results in decreased expression of P2RX7 mRNA | 23195993 |
D019301 | Oleic Acid | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA | 25348860 |
D019301 | Oleic Acid | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein | 25348860 |
D019301 | Oleic Acid | resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA] | 25348860 |
D019301 | Oleic Acid | resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] | 25348860 |
D019308 | Palmitic Acid | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA | 25348860 |
D019308 | Palmitic Acid | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein | 25348860 |
D019308 | Palmitic Acid | resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA] | 25348860 |
D019308 | Palmitic Acid | resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] | 25348860 |
D010269 | Paraquat | Paraquat affects the expression of P2RX7 mRNA | 18198484 |
C004282 | periodate-oxidized adenosine 5'-triphosphate | periodate-oxidized adenosine 5'-triphosphate binds to and results in decreased activity of P2RX7 protein | 17728465 |
D010862 | Pilocarpine | Pilocarpine results in increased expression of P2RX7 protein | 19138473 |
D011070 | Poly I-C | Poly I-C results in decreased expression of P2RX7 protein | 23516405 |
D011070 | Poly I-C | Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RX7 protein] | 23516405 |
D011285 | Pregnenolone Carbonitrile | Pregnenolone Carbonitrile results in increased expression of P2RX7 mRNA | 19162173 |
D047428 | Protein Kinase Inhibitors | Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of P2RX7 mRNA] | 28003376 |
C009090 | protoberberine | protoberberine analog inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] | 21320518 |
C009090 | protoberberine | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] | 21320518 |
C009090 | protoberberine | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK1 protein] | 21320518 |
C009090 | protoberberine | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased phosphorylation of MAPK3 protein] | 21320518 |
C009090 | protoberberine | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL1B protein] | 21320518 |
C009090 | protoberberine | protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased secretion of IL2 protein] | 21320518 |
C009090 | protoberberine | protoberberine analog binds to and results in decreased activity of P2RX7 protein | 21320518 |
C513428 | pyrachlostrobin | pyrachlostrobin results in increased expression of P2RX7 mRNA | 27029645 |
C077792 | pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid | "pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]" | 21638035 |
C077792 | pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid | "pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid binds to and results in decreased activity of P2RX7 protein" | 15258577|2163803 |
C059514 | resveratrol | resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA] | 24149798 |
C059514 | resveratrol | resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein] | 24149798 |
C059514 | resveratrol | resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA] | 25348860 |
C059514 | resveratrol | resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] | 25348860 |
C009250 | sevoflurane | sevoflurane affects the expression of P2RX7 mRNA | 15967596 |
D012822 | Silicon Dioxide | Silicon Dioxide analog results in decreased expression of P2RX7 mRNA | 23806026 |
D012834 | Silver | Silver results in increased expression of P2RX7 mRNA | 27131904 |
D013498 | Suramin | Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RX7 protein] | 23516405 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of P2RX7 mRNA | 22298810 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of P2RX7 mRNA | 21570461|2637764 |
D013755 | Tetradecanoylphorbol Acetate | [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA | 23519560 |
D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of P2RX7 mRNA | 25613284 |
C009495 | titanium dioxide | titanium dioxide results in decreased expression of P2RX7 mRNA | 29128614 |
C009495 | titanium dioxide | titanium dioxide results in increased expression of P2RX7 mRNA | 23557971 |
C009495 | titanium dioxide | titanium dioxide results in increased expression of P2RX7 protein | 28646487 |
D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution affects the expression of P2RX7 mRNA | 20133372 |
D014051 | Toluene 2,4-Diisocyanate | "P2RX7 protein promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of ENPP2 protein]" | 26072274 |
D014118 | Toxins, Biological | "Toxins, Biological affects the expression of P2RX7 mRNA" | 19682533 |
D014302 | Trinitrobenzenesulfonic Acid | Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA | 23537331 |
D001335 | Vehicle Emissions | Vehicle Emissions results in decreased methylation of P2RX7 gene | 25560391 |
D014750 | Vincristine | "[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Vincristine" | 16982702 |
C029297 | vinylidene chloride | vinylidene chloride results in increased expression of P2RX7 mRNA | 26682919 |
D019287 | Zinc Sulfate | Zinc Sulfate results in decreased expression of P2RX7 mRNA | 27215404 |