Gene: CD207

50489
CLEC4K
CD207 molecule
protein-coding
2p13.3
Ensembl:ENSG00000116031 MIM:604862 Vega:OTTHUMG00000153176 UniprotKB:Q9UJ71
NG_033914.1
PubMed
0   ANCO-SNPs
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.414e-1 (AD)  6.310e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CLEC4F0.619
CR20.53
GK0.505
ZNF4310.505
MYEOV0.503
MALT10.499
FUT30.497
CCDC150.49
XRN10.49
CXorf380.49

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ADRA2C-0.348
ARSE-0.332
ZBTB12-0.322
ARSF-0.299
WNT7A-0.279
ASPDH-0.273
HES5-0.27
ZNF771-0.268
GVQW1-0.257
GJB3-0.252

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CD207 mRNA23735875
C006780bisphenol Abisphenol A results in decreased expression of CD207 mRNA25181051
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD207 mRNA20938992
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of CD207 mRNA24317228
C010902decabromobiphenyl etherdecabromobiphenyl ether affects the expression of CD207 mRNA24834073
D004041Dietary FatsDietary Fats affects the expression of CD207 mRNA19680557
D004041Dietary FatsDietary Fats results in increased expression of CD207 mRNA22609946
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of CD207 mRNA28085963
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the expression of CD207 mRNA22302311
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD207 mRNA20938992
C080043hexyl cinnamic aldehydehexyl cinnamic aldehyde affects the expression of CD207 mRNA22302311
C016517indole-3-carbinolindole-3-carbinol affects the expression of CD207 mRNA21396975
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD207 mRNA20938992
D037742Nanotubes, Carbon"Nanotubes, Carbon analog affects the expression of CD207 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of CD207 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CD207 mRNA"25554681
C029938nickel sulfatenickel sulfate results in decreased expression of CD207 protein15588916
C029938nickel sulfatepyrazolanthrone promotes the reaction [nickel sulfate results in decreased expression of CD207 protein]15588916
D000073878Palm OilPalm Oil affects the expression of CD207 mRNA19680557
C008776pelargonic acidpelargonic acid affects the expression of CD207 mRNA22302311
D009764o-Phthalaldehydeo-Phthalaldehyde affects the expression of CD207 mRNA22302311
C432165pyrazolanthronepyrazolanthrone promotes the reaction [nickel sulfate results in decreased expression of CD207 protein]15588916
C432165pyrazolanthronepyrazolanthrone results in decreased expression of CD207 protein15588916
D053260SootSoot results in increased expression of CD207 mRNA26551751
C013698tallowtallow affects the expression of CD207 mRNA19680557
C009495titanium dioxidetitanium dioxide results in increased expression of CD207 mRNA27760801
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CD207 mRNA20133372
C015559trimellitic anhydridetrimellitic anhydride affects the expression of CD207 mRNA22302311
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of CD207 mRNA19042947
C057693troglitazonetroglitazone results in increased expression of CD207 mRNA28973697

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25910212  
GO:0005537mannose binding-TAS10661407  
GO:0030246carbohydrate binding-IDA20026605  
GO ID GO Term Qualifier Evidence PubMed
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-TAS-  
GO:0006898receptor-mediated endocytosis-TAS-  
GO:0051607defense response to virus-IDA17334373  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0016021integral component of membrane-IEA-  
GO:0030139endocytic vesicle-TAS10661407  
GO:0030669clathrin-coated endocytic vesicle membrane-TAS-  
GO:0031901early endosome membrane-TAS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1236975Antigen processing-Cross presentationTAS
R-HSA-1236975Antigen processing-Cross presentationIEA
R-HSA-1236978Cross-presentation of soluble exogenous antigens (endosomes)TAS
R-HSA-1236978Cross-presentation of soluble exogenous antigens (endosomes)IEA
R-HSA-1280218Adaptive Immune SystemTAS
R-HSA-1280218Adaptive Immune SystemIEA
R-HSA-168256Immune SystemTAS
R-HSA-168256Immune SystemIEA
R-HSA-983169Class I MHC mediated antigen processing & presentationTAS
R-HSA-983169Class I MHC mediated antigen processing & presentationIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29083024Pulmonary Langerhans' cell histiocytosis in adults. (2017)Radzikowska EAdv Respir Med
27816338[Adult Langerhans cell histiocytosis]. (2017 Jan)de Menthon MPresse Med