Gene: DEC1

50514
CTS9
deleted in esophageal cancer 1
protein-coding
9q33.1
Ensembl:ENSG00000173077 MIM:604767 Vega:OTTHUMG00000020549 UniprotKB:Q9P2X7
NG_027530.1
PubMed
0   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.623e-1 (AD)  6.393e-3 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KRT33A0.838
ARL14EPL0.78
CRX0.777
RBM460.762
TPRX10.726
FAM170B0.707
TMEM950.704
SBK30.698
HELB0.696
MMP100.694

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CKMT1B-0.376
AMER3-0.366
TBR1-0.366
ASIC2-0.364
CHRM1-0.364
SRRM4-0.356
NEUROD2-0.348
FAM189A1-0.344
STAC2-0.343
KCNT1-0.343

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of DEC1 gene27153756
D017632Asbestos, Serpentine"Asbestos, Serpentine results in decreased expression of DEC1 mRNA"21148743
C045037testosterone-3-carboxymethyloxime-bovine serum albumin conjugatetestosterone-3-carboxymethyloxime-bovine serum albumin conjugate results in decreased expression of DEC1 mRNA20189893
D014635Valproic AcidValproic Acid results in decreased methylation of DEC1 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0008285negative regulation of cell proliferation-TAS10612805  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal