Gene: UTP11

51118
CGI-94|CGI94|UTP11L
UTP11, small subunit processome component
protein-coding
1p34.3
Ensembl:ENSG00000183520 MIM:609440 Vega:OTTHUMG00000004435 UniprotKB:Q9Y3A2
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.055e-1 (AD)  1.190e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11211383chr1:38016684 (GRCh38.p7)T>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C517041(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in increased expression of UTP11 mRNA"19561079
C5538177-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in decreased expression of UTP11 mRNA"19936915
D000082AcetaminophenAcetaminophen results in decreased expression of UTP11 mRNA21420995
D000643Ammonium ChlorideAmmonium Chloride affects the expression of UTP11 mRNA16483693
D001104ArbutinArbutin results in increased expression of UTP11 mRNA17103032
C006780bisphenol Abisphenol A results in decreased expression of UTP11 mRNA29275510
C006780bisphenol Abisphenol A results in decreased expression of UTP11 mRNA25181051
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of UTP11 mRNA23650126
D003300Copper[Disulfiram binds to Copper] which results in decreased expression of UTP11 mRNA24690739
D019327Copper SulfateCopper Sulfate results in increased expression of UTP11 mRNA19549813
C029892cupric chloridecupric chloride results in increased expression of UTP11 mRNA17211630
C030973cupric oxidecupric oxide results in increased expression of UTP11 mRNA22077320
D016572CyclosporineCyclosporine results in increased expression of UTP11 mRNA20106945|2556210
D004221Disulfiram[Disulfiram binds to Copper] which results in decreased expression of UTP11 mRNA24690739
D004785Environmental PollutantsEnvironmental Pollutants results in increased expression of UTP11 mRNA20064776
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of UTP11 protein23301498
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of UTP11 mRNA25613284
C011890kojic acidkojic acid results in increased expression of UTP11 mRNA16595896
D010269ParaquatParaquat results in increased expression of UTP11 mRNA21371552
D010894PiroxicamPiroxicam results in decreased expression of UTP11 mRNA21858171
D010936Plant ExtractsPlant Extracts results in increased expression of UTP11 mRNA23557933
C059514resveratrolresveratrol results in decreased expression of UTP11 protein25505154
D012643SeleniumSelenium results in decreased expression of UTP11 mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of UTP11 mRNA25895662
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of UTP11 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to UTP11 promoter]19654925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of UTP11 mRNA21215274
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of UTP11 mRNA25613284
D014635Valproic AcidValproic Acid affects the expression of UTP11 mRNA25979313
C025643vinclozolinvinclozolin results in increased expression of UTP11 mRNA23869203
D014810Vitamin EVitamin E results in decreased expression of UTP11 mRNA19244175

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22658674  22681889  
GO:0005515protein binding-IPI12559088  25416956  
GO ID GO Term Qualifier Evidence PubMed
GO:0006364rRNA processing-TAS-  
GO:0007399nervous system development-IMP12559088  
GO:0043065positive regulation of apoptotic process-IMP12559088  
GO ID GO Term Qualifier Evidence PubMed
GO:0005615extracellular space-IDA11860508  
GO:0005654nucleoplasm-TAS-  
GO:0005730nucleolus-IBA21873635  
GO:0005730nucleolus-IDA11860508  
GO:0005737cytoplasm-IDA11860508  
GO:0032040small-subunit processome-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-6790901rRNA modification in the nucleus and cytosolIEA
R-HSA-6791226Major pathway of rRNA processing in the nucleolus and cytosolTAS
R-HSA-72312rRNA processingIEA
R-HSA-72312rRNA processingTAS
R-HSA-8868773rRNA processing in the nucleus and cytosolIEA
R-HSA-8868773rRNA processing in the nucleus and cytosolTAS
R-HSA-8953854Metabolism of RNAIEA
R-HSA-8953854Metabolism of RNATAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal