Gene: PHF11

51131
APY|BCAP|IGEL|IGER|IGHER|NY-REN-34|NYREN34
PHD finger protein 11
protein-coding
13q14.2
Ensembl:ENSG00000136147 MIM:607796 Vega:OTTHUMG00000016916 UniprotKB:Q9UIL8
NC_000013.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.935e-1 (AD)  6.790e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DYNLT10.87
PSME10.853
PSME20.852
PSMB80.837
FUCA20.832
AK20.827
B2M0.824
H3F3B0.824
IRF90.823
IFI350.823

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.448
OR4F29-0.439
OPRD1-0.374
HNF1A-0.348
WNT7A-0.346
KLHL34-0.342
ADRA1D-0.338
CYP1A1-0.333
KCNG1-0.331
GPR26-0.331

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHF11 mRNA"27188386
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of PHF11 mRNA19191707
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHF11 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of PHF11 mRNA21420995
D000082AcetaminophenAcetaminophen results in increased expression of PHF11 mRNA26690555
D000082AcetaminophenAcetaminophen affects the expression of PHF11 mRNA17562736
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of PHF11 mRNA21569818
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of PHF11 mRNA22228805
C006780bisphenol Abisphenol A results in decreased expression of PHF11 mRNA19371625
C006780bisphenol Abisphenol A results in increased methylation of PHF11 gene28505145
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF11 mRNA28628672
D002065BuspironeBuspirone results in decreased expression of PHF11 mRNA24136188
D002922CiguatoxinsCiguatoxins affects the expression of PHF11 mRNA18353800
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of PHF11 mRNA20971185
D019327Copper SulfateCopper Sulfate affects the expression of PHF11 mRNA19549813
D003471CuprizoneCuprizone results in increased expression of PHF11 mRNA26577399
D016572CyclosporineCyclosporine results in increased expression of PHF11 mRNA25562108
C014347decitabinedecitabine inhibits the reaction [Smoke results in decreased expression of PHF11 mRNA]21095227
D003703DemecolcineDemecolcine results in increased expression of PHF11 mRNA23649840
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF11 mRNA28628672
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of PHF11 mRNA19647056
D004237DiuronDiuron results in decreased expression of PHF11 mRNA21551480
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PHF11 mRNA22079256
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of PHF11 mRNA23649840
D015025ZearalenoneZearalenone results in decreased expression of PHF11 mRNA19371625
D005485FlutamideFlutamide results in increased expression of PHF11 mRNA24136188
D005557FormaldehydeFormaldehyde results in increased expression of PHF11 mRNA23649840
D005839GentamicinsGentamicins results in increased expression of PHF11 mRNA22061828
C004312glycidolglycidol results in increased expression of PHF11 mRNA24915197
D017313FenretinideFenretinide results in decreased expression of PHF11 mRNA28973697
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF11 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PHF11 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF11 mRNA28628672
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of PHF11 mRNA23649840
D009532NickelNickel results in increased expression of PHF11 mRNA24768652|2558310
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of PHF11 mRNA20971185
D010081OxazoloneOxazolone results in increased expression of PHF11 mRNA19647056
D052638Particulate MatterPHF11 gene SNP affects the susceptibility to Particulate Matter19590686
D010936Plant ExtractsPlant Extracts results in increased expression of PHF11 mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PHF11 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of PHF11 mRNA22079256|2271453
D011441PropylthiouracilPropylthiouracil results in decreased expression of PHF11 mRNA24780913
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA19059307
D012906Smokedecitabine inhibits the reaction [Smoke results in decreased expression of PHF11 mRNA]21095227
D013629Tamoxifen[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA19059307
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of PHF11 mRNA21570461
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PHF11 mRNA25613284
C009495titanium dioxidetitanium dioxide affects the expression of PHF11 mRNA27760801
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of PHF11 mRNA"19647056
D014212TretinoinTretinoin results in increased expression of PHF11 mRNA21934132
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHF11 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of PHF11 mRNA24935251|2627250
D014520UrethaneUrethane results in decreased expression of PHF11 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of PHF11 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of PHF11 mRNA23179753|2493525
D014750VincristineVincristine results in increased expression of PHF11 mRNA23649840
C111237vorinostatvorinostat results in decreased expression of PHF11 mRNA18769122|2208335

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006355regulation of transcription, DNA-templated-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-IDA-  
GO:0031965nuclear membrane-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29796116Genome-wide analysis of DNA methylation in bronchial washings. (2018)Um SWClin Epigenetics