Gene: DACT1

51339
DAPPER|DAPPER1|DPR1|FRODO|HDPR1|TBS2|THYEX3
dishevelled binding antagonist of beta catenin 1
protein-coding
14q23.1
Ensembl:ENSG00000165617 MIM:607861 Vega:OTTHUMG00000140324 UniprotKB:Q9NYF0
NG_032025.1
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.813e-1 (AD)  5.900e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CDC42EP30.746
RGMB0.736
CNR10.731
DIAPH10.727
AFAP10.725
TMEM1960.724
ANKRD60.723
BICD20.722
MAN1A10.722
NIPA20.721

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CTNNA3-0.357
OR4F5-0.327
BCAS1-0.326
C5orf64-0.32
PAIP2B-0.317
OLAH-0.317
HBA2-0.294
OTOS-0.294
TNFRSF13B-0.293
ZFP57-0.292

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of DACT1 mRNA"25510870
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of DACT1 mRNA"21394737
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the expression of DACT1 mRNA"19414516
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of DACT1 mRNA"19114083
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of DACT1 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of DACT1 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of DACT1 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of DACT1 mRNA"25510870
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of DACT1 mRNA29067470
D016604Aflatoxin B1Aflatoxin B1 affects the expression of DACT1 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of DACT1 mRNA22100608
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of DACT1 mRNA21298039
D000638AmiodaroneAmiodarone results in decreased expression of DACT1 mRNA24535564
C006632arsenic trioxidearsenic trioxide results in decreased expression of DACT1 mRNA27829220
C006632arsenic trioxidearsenic trioxide results in decreased methylation of DACT1 promoter21176356
C006632arsenic trioxide[arsenic trioxide results in decreased methylation of DACT1 promoter] which results in increased expression of DACT1 mRNA21176356|2117635
C487081belinostatbelinostat results in increased expression of DACT1 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of DACT1 mRNA20713471|2156981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of DACT1 mRNA19770486
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of DACT1 mRNA20660070
D004958Estradiol[Progesterone co-treated with Estradiol] results in decreased expression of DACT1 mRNA17404688
D004958EstradiolEstradiol results in decreased expression of DACT1 mRNA19484750|2521013
C006780bisphenol Abisphenol A affects the expression of DACT1 mRNA20170705
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DACT1 mRNA22079614
C018475butyraldehydebutyraldehyde results in increased expression of DACT1 mRNA26079696
D002220CarbamazepineCarbamazepine affects the expression of DACT1 mRNA22634333
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DACT1 gene20938992
C018021cobaltous chloridecobaltous chloride results in decreased expression of DACT1 mRNA24386269
D003471CuprizoneCuprizone results in increased expression of DACT1 mRNA26577399
D016572CyclosporineCyclosporine results in decreased expression of DACT1 mRNA27989131
D016572CyclosporineCyclosporine results in decreased expression of DACT1 mRNA19770486
D000069439DasatinibDasatinib results in increased expression of DACT1 mRNA20579391
C014347decitabine[decitabine affects the methylation of DACT1 promoter] which affects the expression of DACT1 mRNA18538736|1853873
C014347decitabinedecitabine results in decreased expression of DACT1 mRNA27915011
D003907DexamethasoneDexamethasone results in decreased expression of DACT1 mRNA25047013
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of DACT1 mRNA28628672
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of DACT1 mRNA21266533
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of DACT1 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of DACT1 mRNA27392435
D004041Dietary FatsDietary Fats results in increased expression of DACT1 mRNA21852083
D004041Dietary Fatsresveratrol inhibits the reaction [Dietary Fats results in increased expression of DACT1 mRNA]21852083
D004137DinitrochlorobenzeneDinitrochlorobenzene results in decreased expression of DACT1 mRNA18242016
D004237DiuronDiuron results in decreased expression of DACT1 mRNA25152437
C118739entinostatentinostat results in increased expression of DACT1 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
D000431EthanolEthanol results in decreased expression of DACT1 mRNA28986285
C024565ethylene dichlorideethylene dichloride results in decreased expression of DACT1 mRNA28189721
D005411Flame RetardantsFlame Retardants results in increased expression of DACT1 mRNA27219277
C061365flusilazoleflusilazole results in increased expression of DACT1 mRNA22382673
C061365flusilazoleflusilazole affects the expression of DACT1 mRNA22634333
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DACT1 gene20938992
D055768Halogenated Diphenyl EthersHalogenated Diphenyl Ethers results in increased expression of DACT1 mRNA27219277
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of DACT1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of DACT1 mRNA28628672
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of DACT1 mRNA27392435
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DACT1 gene20938992
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of DACT1 mRNA20713471
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of DACT1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of DACT1 mRNA"25620056
D009532NickelNickel results in decreased expression of DACT1 mRNA25583101
C029938nickel sulfatenickel sulfate results in decreased expression of DACT1 mRNA22714537
D010081OxazoloneOxazolone results in decreased expression of DACT1 mRNA18242016
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of DACT1 mRNA26272509
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of DACT1 mRNA"25510870
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of DACT1 mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of DACT1 mRNA23811191
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of DACT1 mRNA22714537
D011192Potassium DichromatePotassium Dichromate results in decreased expression of DACT1 mRNA23608068
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of DACT1 mRNA20660070
D011374Progesterone[Progesterone co-treated with Estradiol] results in decreased expression of DACT1 mRNA17404688
D011374ProgesteroneProgesterone results in decreased expression of DACT1 mRNA17404688
D011441PropylthiouracilPropylthiouracil results in increased expression of DACT1 mRNA24780913
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA19059307
C059514resveratrolresveratrol inhibits the reaction [Dietary Fats results in increased expression of DACT1 mRNA]21852083
D012643SeleniumSelenium results in decreased expression of DACT1 mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of DACT1 mRNA25895662
C017947sodium arsenitesodium arsenite results in decreased expression of DACT1 mRNA22714537
D053260SootSoot results in decreased expression of DACT1 mRNA26551751
D013629Tamoxifen[Tamoxifen co-treated with ESR2 protein] results in increased expression of DACT1 mRNA19059307
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of DACT1 mRNA21570461
D013853ThioacetamideThioacetamide results in decreased expression of DACT1 mRNA23411599
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of DACT1 mRNA28065790
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in decreased expression of DACT1 mRNA"18242016
D014212TretinoinTretinoin results in increased expression of DACT1 mRNA21934132
D014212TretinoinTretinoin results in increased expression of DACT1 mRNA20488242
D014241TrichloroethyleneTrichloroethylene results in decreased expression of DACT1 mRNA25549359
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of DACT1 mRNA24935251|2627250
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of DACT1 mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of DACT1 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in decreased expression of DACT1 mRNA24535564
D014638VanadatesVanadates results in increased expression of DACT1 mRNA22714537
D002762CholecalciferolCholecalciferol results in increased expression of DACT1 mRNA17170073
D014810Vitamin EVitamin E results in decreased expression of DACT1 mRNA19244175
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA"27188386
C111237vorinostatvorinostat results in increased expression of DACT1 mRNA26272509

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0001085RNA polymerase II transcription factor binding-IPI18936100  
GO:0005080protein kinase C binding-IBA21873635  
GO:0005080protein kinase C binding-ISS-  
GO:0005515protein binding-IPI16446366  21262972  22470507  22610794  
GO:0008013beta-catenin binding-IBA21873635  
GO:0008013beta-catenin binding-IDA18936100  22470507  
GO:0008013beta-catenin binding-IPI18936100  
GO:0042826histone deacetylase binding-IPI18936100  
GO:0051018protein kinase A binding-IBA21873635  
GO:0051018protein kinase A binding-IDA21262972  
GO:0070097delta-catenin binding-IBA21873635  
GO:0070097delta-catenin binding-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IDA18936100  
GO:0016055Wnt signaling pathway-IEA-  
GO:0021915neural tube development-IMP22610794  
GO:0030111regulation of Wnt signaling pathway-IBA21873635  
GO:0030177positive regulation of Wnt signaling pathway-IDA21262972  
GO:0030178negative regulation of Wnt signaling pathway-IDA16446366  17197390  
GO:0030178negative regulation of Wnt signaling pathway-IGI16446366  
GO:0030178negative regulation of Wnt signaling pathway-IMP18936100  
GO:0031647regulation of protein stability-IDA21262972  
GO:0032091negative regulation of protein binding-IGI18936100  
GO:0032092positive regulation of protein binding-IGI18936100  
GO:0045732positive regulation of protein catabolic process-IDA16446366  
GO:0046329negative regulation of JNK cascade-IDA17197390  
GO:0048619embryonic hindgut morphogenesis-ISS-  
GO:0060828regulation of canonical Wnt signaling pathway-IMP18936100  
GO:0090090negative regulation of canonical Wnt signaling pathway-IGI18936100  
GO:0090090negative regulation of canonical Wnt signaling pathway-IMP22610794  
GO:0090090negative regulation of canonical Wnt signaling pathway-TAS-  
GO:0090263positive regulation of canonical Wnt signaling pathway-IMP15580286  
GO:1900107regulation of nodal signaling pathwayNOTIDA17197390  
GO:1903364positive regulation of cellular protein catabolic process-IDA16446366  
GO:1903364positive regulation of cellular protein catabolic process-IMP18936100  
GO:1904864negative regulation of beta-catenin-TCF complex assembly-IDA18936100  
GO:2000095regulation of Wnt signaling pathway, planar cell polarity pathway-IBA21873635  
GO:2000095regulation of Wnt signaling pathway, planar cell polarity pathway-ISS-  
GO:2000134negative regulation of G1/S transition of mitotic cell cycle-IDA18936100  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA18936100  
GO:0005654nucleoplasm-IDA-  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-IDA16446366  18936100  22610794  
GO:0005829cytosol-TAS-  
GO:0030054cell junction-IEA-  
GO:0030877beta-catenin destruction complexcolocalizes_withIDA22470507  
GO:0045202synapse-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-195721Signaling by WNTTAS
R-HSA-201681TCF dependent signaling in response to WNTTAS
R-HSA-4641258Degradation of DVLTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23244112Relationships among MTHFR a1298c gene polymorphisms and methylation status of Dact1 gene in transitional cell carcinomas. (2012)Cheng HAsian Pac J Cancer Prev