Gene: ZMYND10

51364
BLU|CILD22|FLU
zinc finger MYND-type containing 10
protein-coding
3p21.31
Ensembl:ENSG00000004838 MIM:607070 Vega:OTTHUMG00000156874 UniprotKB:O75800
NG_042828.1
PubMed
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.408e-1 (AD)  7.126e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SYNDIG1L0.727
COCH0.709
DGKK0.707
C20orf270.707
DRD20.704
PENK0.703
LHX80.702
SLC18A30.701
SLC35D30.7
ANKRD34B0.699

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
COL4A3-0.309
ARHGAP29-0.307
P2RY14-0.293
ABCB4-0.289
OR4F5-0.281
TBX15-0.275
FCGR3B-0.271
ENPEP-0.269
IL18RAP-0.269
EDNRA-0.268

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of ZMYND10 mRNA"19114083
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of ZMYND10 mRNA25088246
D020106AcrylamideAcrylamide results in increased expression of ZMYND10 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of ZMYND10 gene28458013
D000638AmiodaroneAmiodarone results in increased expression of ZMYND10 mRNA19774075
C015001arsenitearsenite results in decreased expression of ZMYND10 mRNA18929588
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of ZMYND10 mRNA26377693
C006780bisphenol Abisphenol A affects the expression of ZMYND10 mRNA20170705
C006780bisphenol Abisphenol A results in decreased methylation of ZMYND10 promoter27312807
C006780bisphenol Abisphenol A affects the expression of ZMYND10 mRNA25181051
D002737ChloropreneChloroprene results in increased expression of ZMYND10 mRNA23125180
D003471CuprizoneCuprizone results in increased expression of ZMYND10 mRNA26577399
C014347decitabine[decitabine co-treated with trichostatin A] affects the expression of ZMYND10 mRNA18819746
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of ZMYND10 mRNA19371625
C118739entinostatentinostat results in increased expression of ZMYND10 mRNA27188386
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZMYND10 mRNA17942748
D015025ZearalenoneZearalenone results in decreased expression of ZMYND10 mRNA19371625
C039281furanfuran results in decreased expression of ZMYND10 mRNA25539665
C008261lead acetatelead acetate affects the expression of ZMYND10 mRNA21864555
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ZMYND10 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ZMYND10 mRNA"25554681
C006253pirinixic acidpirinixic acid results in increased expression of ZMYND10 mRNA23811191
C017947sodium arsenitesodium arsenite results in increased methylation of ZMYND10 gene24570342
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ZMYND10 mRNA26377647
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZMYND10 mRNA17942748
C009495titanium dioxidetitanium dioxide affects the expression of ZMYND10 mRNA23557971
C012589trichostatin A[decitabine co-treated with trichostatin A] affects the expression of ZMYND10 mRNA18819746
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of ZMYND10 mRNA"26179874
D014635Valproic AcidValproic Acid results in increased methylation of ZMYND10 gene29154799
D014640VancomycinVancomycin results in increased expression of ZMYND10 mRNA18930951

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI16189514  23891469  23891471  25416956  29601588  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0036158outer dynein arm assembly-IBA21873635  
GO:0036158outer dynein arm assembly-IMP23891469  23891471  
GO:0036158outer dynein arm assembly-ISS-  
GO:0036159inner dynein arm assembly-IBA21873635  
GO:0036159inner dynein arm assembly-IMP23891469  23891471  
GO:0036159inner dynein arm assembly-ISS-  
GO:0044458motile cilium assembly-IBA21873635  
GO:0044458motile cilium assembly-IMP23891469  23891471  
GO:1905505positive regulation of motile cilium assembly-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-IDA-  
GO:0016324apical plasma membrane-ISS-  
GO:0034451centriolar satellite-IBA21873635  
GO:0034451centriolar satellite-ISS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25657825Identification and validation of the methylation biomarkers of non-small cell lung cancer (NSCLC). (2015)Guo SClin Epigenetics
19334046Current smoking-specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer. (2009 Jun)Boelens MCJ Pathol