| C025205 | 1,10-phenanthroline | "1,10-phenanthroline results in increased expression of PDK1 mRNA" | 19502547 |
| C070379 | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester | "1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]" | 28887310 |
| C070379 | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester | "1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]" | 28887310 |
| C068543 | 1,2-diethyl-3-hydroxypyridin-4-one | "1,2-diethyl-3-hydroxypyridin-4-one results in increased expression of PDK1 mRNA" | 21558026 |
| C068543 | 1,2-diethyl-3-hydroxypyridin-4-one | "1,2-diethyl-3-hydroxypyridin-4-one results in increased expression of PDK1 mRNA" | 21558026 |
| C576882 | 1-(2-trifluoromethoxyphenyl)-2-nitroethanone | 1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in decreased expression of PDK1 mRNA | 25596134 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of PDK1 mRNA" | 22698814|2890350 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "NR1I3 protein promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of PDK1 mRNA]" | 22698814 |
| C051246 | 1-methylanthracene | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of PDK1 mRNA | 28329830 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PDK1 protein binds to AKT1 protein] which results in decreased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine" | 20361045 |
| C548651 | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of PDK1 mRNA | 19933214 |
| C111118 | 2',3,3',4',5-pentachloro-4-hydroxybiphenyl | "2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of PDK1 mRNA" | 19114083 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | "2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA]" | 21851831 |
| C016403 | 2,4-dinitrotoluene | "2,4-dinitrotoluene affects the expression of PDK1 mRNA" | 21346803 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the localization of [PDK1 protein binds to AKT1 protein] | 20361045 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | [PDK1 protein binds to AKT1 protein] inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of AKT1 protein] | 20361045 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | [PDK1 protein binds to AKT1 protein] inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of RPS6 protein] | 20361045 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | [PDK1 protein binds to AKT1 protein] results in decreased susceptibility to [Paclitaxel co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] | 20361045 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | [PDK1 protein binds to AKT1 protein] which results in decreased susceptibility to 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 20361045 |
| C023514 | 2,6-dinitrotoluene | "2,6-dinitrotoluene results in increased expression of PDK1 mRNA" | 20406850 |
| C031278 | 2-chloroethyl ethyl sulfide | 2-chloroethyl ethyl sulfide results in decreased expression of PDK1 mRNA | 12208782 |
| C031278 | 2-chloroethyl ethyl sulfide | 2-chloroethyl ethyl sulfide results in decreased expression of PDK1 protein | 12208782 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA" | 27188386 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of PDK1 mRNA | 25704631 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of PDK1 mRNA | 17562736 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | 17171638 |
| C027696 | acipimox | acipimox results in decreased expression of PDK1 mRNA | 25352640 |
| D000242 | Cyclic AMP | "1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]" | 28887310 |
| D000242 | Cyclic AMP | N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| D000242 | Cyclic AMP | PDK1 protein affects the abundance of Cyclic AMP | 28887310 |
| D000242 | Cyclic AMP | [PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP | 28887310 |
| D000242 | Cyclic AMP | tubacin affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| D000242 | Cyclic AMP | tubacin affects the reaction [[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP] | 28887310 |
| D000242 | Cyclic AMP | tubastatin A affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| D000242 | Cyclic AMP | W 7 affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| D000255 | Adenosine Triphosphate | Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium] | 28887310 |
| D000255 | Adenosine Triphosphate | PDK1 protein affects the susceptibility to Adenosine Triphosphate | 28887310 |
| D000255 | Adenosine Triphosphate | [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium | 28887310 |
| D000255 | Adenosine Triphosphate | tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium] | 28887310 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased expression of PDK1 mRNA | 21641981 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased expression of PDK1 mRNA | 19770486 |
| C501521 | Akt-I-1,2 compound | "[PDK1 protein binds to AKT1 protein] which results in decreased susceptibility to Akt-I-1,2 compound" | 20361045 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of PDK1 mRNA | 16483693 |
| D001280 | Atrazine | Atrazine results in decreased expression of PDK1 mRNA | 25929836 |
| D001374 | Azacitidine | Azacitidine results in increased expression of PDK1 mRNA | 20823114 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of PDK1 mRNA | 20106945|2163298 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of PDK1 mRNA | 22610609 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PDK1 mRNA" | 20382639 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA | 25566086 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA] | 25566086 |
| D004958 | Estradiol | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA | 20823114 |
| D001663 | Bilirubin | Bilirubin results in decreased expression of PDK1 mRNA | 20196124 |
| C002791 | bismuth tripotassium dicitrate | bismuth tripotassium dicitrate results in increased expression of PDK1 mRNA | 15912405 |
| C006780 | bisphenol A | bisphenol A affects the expression of PDK1 mRNA | 21786754 |
| C006780 | bisphenol A | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA | 28628672 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of PDK1 mRNA | 27296223 |
| C006780 | bisphenol A | bisphenol A results in increased expression of PDK1 mRNA | 12075121|2518105 |
| C006780 | bisphenol A | [Fructose co-treated with bisphenol A] results in increased expression of PDK1 protein | 26930160 |
| D019328 | Buthionine Sulfoximine | Buthionine Sulfoximine promotes the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | 17171638 |
| C018475 | butyraldehyde | butyraldehyde results in decreased expression of PDK1 mRNA | 26079696 |
| D002104 | Cadmium | PDK1 promotes the reaction [Cadmium results in increased expression of MT1A mRNA] | 28632756 |
| D002118 | Calcium | PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] | 28634229 |
| D002118 | Calcium | "1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]" | 28887310 |
| D002118 | Calcium | Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium] | 28887310 |
| D002118 | Calcium | PDK1 protein affects the abundance of Calcium | 28887310 |
| D002118 | Calcium | PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium] | 28887310 |
| D002118 | Calcium | [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium | 28887310 |
| D002118 | Calcium | tubacin affects the reaction [PDK1 protein affects the abundance of Calcium] | 28887310 |
| D002118 | Calcium | tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium] | 28887310 |
| D002118 | Calcium | tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]] | 28887310 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of PDK1 mRNA | 25979313 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of PDK1 mRNA | 27339419 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of PDK1 mRNA | 23650126 |
| D020245 | p-Chloromercuribenzoic Acid | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| D020245 | p-Chloromercuribenzoic Acid | p-Chloromercuribenzoic Acid results in decreased expression of PDK1 mRNA | 26272509 |
| D002746 | Chlorpromazine | Chlorpromazine results in increased expression of PDK1 mRNA | 25596134 |
| C012843 | cinnamic aldehyde | cinnamic aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of PDK1 protein] | 20467561 |
| D004002 | Clodronic Acid | Clodronic Acid results in decreased expression of PDK1 mRNA | 25596134 |
| D003035 | Cobalt | [tungsten carbide binds to Cobalt] which results in increased expression of PDK1 mRNA | 20105288 |
| C018021 | cobaltous chloride | cobaltous chloride results in increased expression of PDK1 mRNA | 19502547|2010528 |
| C018021 | cobaltous chloride | zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] | 22202117 |
| C018021 | cobaltous chloride | cobaltous chloride results in increased expression of PDK1 mRNA | 21558026|2438626 |
| C060728 | cobalt oxide | cobalt oxide analog results in increased expression of PDK1 mRNA | 24821434 |
| C026305 | cobalt sulfate | cobalt sulfate results in increased expression of PDK1 mRNA | 19502547 |
| D005576 | Colforsin | PDK1 protein affects the susceptibility to Colforsin | 28887310 |
| D005576 | Colforsin | [PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP | 28887310 |
| D005576 | Colforsin | tubacin affects the reaction [[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP] | 28887310 |
| D003300 | Copper | Copper results in increased expression of PDK1 mRNA | 22465980 |
| D003345 | Corticosterone | Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein | 21655274 |
| D003345 | Corticosterone | [Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein] which results in increased phosphorylation of and results in increased activity of SGK1 protein | 21655274 |
| D003474 | Curcumin | Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | 17171638 |
| D003474 | Curcumin | Buthionine Sulfoximine promotes the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | 17171638 |
| D003474 | Curcumin | Curcumin results in increased phosphorylation of PDK1 protein | 17171638 |
| D003474 | Curcumin | Glutathione inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | 17171638 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of PDK1 mRNA | 21632981|2556210 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of PDK1 mRNA | 25596134 |
| D003676 | Deferoxamine | Deferoxamine results in increased expression of PDK1 mRNA | 21558026 |
| C107676 | deguelin | deguelin metabolite results in decreased expression of PDK1 protein | 19139008 |
| C107676 | deguelin | deguelin results in decreased expression of PDK1 protein | 19139008 |
| D003703 | Demecolcine | Demecolcine results in decreased expression of PDK1 mRNA | 23649840 |
| D017485 | 1-Deoxynojirimycin | [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] | 25446853 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA | 28628672 |
| D003907 | Dexamethasone | Dexamethasone results in increased phosphorylation of PDK1 protein | 21655274 |
| D003907 | Dexamethasone | wortmannin inhibits the reaction [Dexamethasone results in increased phosphorylation of PDK1 protein] | 21655274 |
| D064730 | Dexrazoxane | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of PDK1 mRNA | 26873546 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of PDK1 mRNA | 21266533 |
| D003994 | Bucladesine | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA | 20823114 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of PDK1 mRNA | 24280081|2559613 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of PDK1 mRNA | 24280081 |
| C036042 | dicyclohexyl phthalate | dicyclohexyl phthalate affects the expression of PDK1 mRNA | 26924002 |
| D004026 | Dieldrin | Dieldrin results in decreased expression of PDK1 mRNA | 23153324 |
| D004041 | Dietary Fats | [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] | 25446853 |
| D004041 | Dietary Fats | [Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA | 25446853 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of PDK1 mRNA | 19030233 |
| D004041 | Dietary Fats | Dietary Fats results in increased expression of PDK1 mRNA | 25016146 |
| D004042 | Dietary Fats, Unsaturated | "Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of PDK1 mRNA]" | 23626681 |
| D004052 | Diethylnitrosamine | CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of PDK1 protein] | 20583210 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in increased phosphorylation of PDK1 protein | 20583210 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in increased expression of PDK1 protein modified form | 19931519 |
| D004052 | Diethylnitrosamine | morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] | 19931519 |
| D004317 | Doxorubicin | Doxorubicin results in increased expression of PDK1 mRNA | 28940058 |
| D004317 | Doxorubicin | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of PDK1 mRNA | 26873546 |
| D004317 | Doxorubicin | Doxorubicin results in decreased expression of PDK1 mRNA | 26873546 |
| C045651 | epigallocatechin gallate | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PDK1 mRNA | 22079256 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in decreased expression of PDK1 mRNA | 23649840 |
| D011345 | Fenofibrate | Fenofibrate results in decreased expression of PDK1 mRNA | 25596134 |
| C007738 | fluoranthene | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of PDK1 mRNA | 28329830 |
| D005557 | Formaldehyde | Formaldehyde results in decreased expression of PDK1 mRNA | 23649840 |
| D005632 | Fructose | [Fructose co-treated with bisphenol A] results in increased expression of PDK1 protein | 26930160 |
| D019833 | Genistein | Genistein results in decreased phosphorylation of PDK1 protein | 18431742 |
| D005839 | Gentamicins | Gentamicins results in increased expression of PDK1 mRNA | 22061828 |
| D005947 | Glucose | Glucose affects the expression of PDK1 mRNA | 24349266 |
| D005947 | Glucose | PDK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose] | 14711829 |
| D005978 | Glutathione | Glutathione inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | 17171638 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in decreased expression of PDK1 mRNA | 24349266 |
| D007069 | Ifosfamide | Ifosfamide results in decreased expression of PDK1 mRNA | 25596134 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA | 28628672 |
| D015759 | Ionomycin | PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] | 28634229 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PDK1 mRNA | 25613284 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA | 28628672 |
| C040920 | isoliquiritigenin | isoliquiritigenin results in decreased phosphorylation of PDK1 protein | 25094029 |
| D007545 | Isoproterenol | Isoproterenol results in increased expression of PDK1 mRNA | 20003209 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound inhibits the reaction [PDK1 gene mutant form promotes the reaction [BRD4 protein binds to MYC promoter]] | 25877301 |
| D007854 | Lead | Lead results in decreased expression of PDK1 mRNA | 19921347 |
| D008070 | Lipopolysaccharides | cinnamic aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of PDK1 protein] | 20467561 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased phosphorylation of PDK1 protein | 20467561 |
| D008345 | Manganese | Manganese results in increased expression of PDK1 mRNA | 17175027 |
| C025340 | manganese chloride | manganese chloride results in increased expression of PDK1 mRNA | 17175027 |
| D017258 | Medroxyprogesterone Acetate | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA | 20823114 |
| C042720 | mercuric bromide | mercuric bromide results in decreased expression of PDK1 mRNA | 26272509 |
| C042720 | mercuric bromide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| D008687 | Metformin | Metformin affects the expression of PDK1 mRNA | 25596134 |
| D008727 | Methotrexate | PDK1 protein affects the susceptibility to Methotrexate | 16217747 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of PDK1 mRNA | 23179753|2718838 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in decreased expression of PDK1 mRNA | 23649840 |
| D018817 | N-Methyl-3,4-methylenedioxyamphetamine | "N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of PDK1 mRNA" | 26251327 |
| D008770 | Methylnitrosourea | Methylnitrosourea results in increased expression of PDK1 mRNA | 16525678 |
| C008548 | morin | morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] | 19931519 |
| D009020 | Morphine | Morphine results in decreased expression of PDK1 protein | 23056601 |
| C583365 | N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide | "N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of PDK1 mRNA" | 29244179 |
| C033772 | N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide | N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon analog results in decreased expression of PDK1 mRNA" | 25620056 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in decreased expression of PDK1 mRNA" | 25620056 |
| C017096 | n-butoxyethanol | n-butoxyethanol results in increased expression of PDK1 mRNA | 19812364 |
| C022838 | nickel chloride | nickel chloride results in increased expression of PDK1 mRNA | 21455298 |
| C022838 | nickel chloride | nickel chloride results in increased expression of PDK1 mRNA | 22110744 |
| C025256 | nonylphenol | nonylphenol results in decreased expression of PDK1 mRNA | 27832966 |
| C025589 | ochratoxin A | ochratoxin A affects the phosphorylation of PDK1 protein | 25002221 |
| C025589 | ochratoxin A | ochratoxin A results in increased expression of PDK1 protein | 17651772 |
| C025589 | ochratoxin A | ochratoxin A results in increased phosphorylation of PDK1 protein | 17651772 |
| C108709 | oleoyl-estrone | oleoyl-estrone results in decreased expression of PDK1 mRNA | 17725831 |
| D010100 | Oxygen | IL15 protein promotes the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] | 27129235 |
| D010100 | Oxygen | Oxygen deficiency results in increased expression of PDK1 mRNA | 17175027|1767120 |
| D010100 | Oxygen | [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] | 17671207 |
| D010100 | Oxygen | vorinostat inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 protein] | 26305601 |
| D010100 | Oxygen | Oxygen deficiency results in increased expression of PDK1 mRNA | 20880076 |
| D017239 | Paclitaxel | [PDK1 protein binds to AKT1 protein] results in decreased susceptibility to [Paclitaxel co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] | 20361045 |
| D017239 | Paclitaxel | [PDK1 protein binds to AKT1 protein] which results in decreased susceptibility to Paclitaxel | 20361045 |
| D010433 | Pentylenetetrazole | [Pentylenetetrazole co-treated with Vigabatrin] affects the expression of PDK1 mRNA | 21503142 |
| C101816 | perfluoro-n-nonanoic acid | perfluoro-n-nonanoic acid results in decreased expression of PDK1 protein modified form | 22387981 |
| C023036 | perfluorooctanoic acid | "Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of PDK1 mRNA]" | 23626681 |
| D026023 | Permethrin | Permethrin inhibits the reaction [INS1 protein results in increased phosphorylation of PDK1 protein] | 24911977 |
| D010634 | Phenobarbital | Phenobarbital results in decreased expression of PDK1 mRNA | 19162173 |
| D010662 | Phenylmercuric Acetate | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA" | 27188386 |
| D010662 | Phenylmercuric Acetate | Phenylmercuric Acetate results in decreased expression of PDK1 mRNA | 26272509 |
| C522973 | PI103 | [PDK1 protein binds to AKT1 protein] which results in decreased susceptibility to PI103 | 20361045 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PDK1 mRNA | 19710929 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of PDK1 mRNA | 23811191 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of PDK1 mRNA | 17426115 |
| D059808 | Polyphenols | Polyphenols results in decreased expression of PDK1 mRNA | 16293270 |
| D011134 | Polysaccharides | [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] | 25446853 |
| C027373 | potassium chromate(VI) | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PDK1 mRNA | 22079256 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in increased expression of PDK1 mRNA | 22079256 |
| C045950 | propiconazole | propiconazole results in decreased expression of PDK1 mRNA | 21278054 |
| D011794 | Quercetin | Quercetin results in decreased expression of PDK1 mRNA | 21632981 |
| D015125 | Oxyquinoline | Oxyquinoline results in decreased expression of PDK1 mRNA | 21632981 |
| C059514 | resveratrol | resveratrol results in decreased expression of PDK1 protein | 24395567 |
| C059514 | resveratrol | sirtinol inhibits the reaction [resveratrol results in decreased expression of PDK1 protein] | 24395567 |
| C089730 | rosiglitazone | rosiglitazone affects the expression of PDK1 mRNA | 22013433 |
| D012402 | Rotenone | [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] | 17671207 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in decreased expression of PDK1 mRNA | 25895662 |
| C439060 | sirtinol | sirtinol inhibits the reaction [resveratrol results in decreased expression of PDK1 protein] | 24395567 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of PDK1 mRNA | 27287256 |
| D012969 | Sodium Fluoride | Sodium Fluoride results in decreased expression of PDK1 protein | 28918527 |
| D053260 | Soot | Soot results in decreased expression of PDK1 mRNA | 22461453 |
| D013311 | Streptozocin | [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] | 25446853 |
| D013311 | Streptozocin | [Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA | 25446853 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased phosphorylation of PDK1 protein | 27312872 |
| D013749 | Tetrachlorodibenzodioxin | "2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA]" | 21851831 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of PDK1 mRNA | 21570461|2637764 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA | 19770486|2185183 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of PDK1 mRNA | 19933214 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of PDK1 mRNA | 22298810 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PDK1 mRNA | 25613284 |
| D019284 | Thapsigargin | PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium] | 28887310 |
| D019284 | Thapsigargin | tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]] | 28887310 |
| D013804 | Thenoyltrifluoroacetone | [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] | 17671207 |
| D013849 | Thimerosal | Thimerosal results in decreased expression of PDK1 mRNA | 27188386 |
| C009495 | titanium dioxide | titanium dioxide results in decreased expression of PDK1 mRNA | 23557971|2776080 |
| D014212 | Tretinoin | Tretinoin results in increased expression of PDK1 mRNA | 21934132 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of PDK1 mRNA | 16604517 |
| C012589 | trichostatin A | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA" | 27188386 |
| C012589 | trichostatin A | trichostatin A results in increased expression of PDK1 mRNA | 24935251|2627250 |
| C012589 | trichostatin A | trichostatin A results in increased expression of PDK1 mRNA | 15901671 |
| C474316 | tubacin | tubacin affects the reaction [PDK1 protein affects the abundance of Calcium] | 28887310 |
| C474316 | tubacin | tubacin affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| C474316 | tubacin | tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium] | 28887310 |
| C474316 | tubacin | tubacin affects the reaction [[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP] | 28887310 |
| C474316 | tubacin | tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]] | 28887310 |
| C553587 | tubastatin A | tubastatin A affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| C002802 | tungsten carbide | [tungsten carbide binds to Cobalt] which results in increased expression of PDK1 mRNA | 20105288 |
| C002802 | tungsten carbide | tungsten carbide results in increased expression of PDK1 mRNA | 20105288 |
| C022884 | undecane | undecane results in decreased expression of PDK1 protein | 17337753 |
| D014520 | Urethane | Urethane results in decreased expression of PDK1 mRNA | 28818685 |
| C073339 | usnic acid | usnic acid results in decreased phosphorylation of PDK1 protein | 25078063 |
| C406224 | valdecoxib | valdecoxib results in decreased expression of PDK1 mRNA | 24136188 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid results in decreased expression of PDK1 mRNA | 23179753|2718838 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of PDK1 mRNA | 23179753|2438349 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of PDK1 mRNA | 24489787 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of PDK1 mRNA | 15901671 |
| C000602510 | VER-246608 | VER-246608 results in decreased activity of PDK1 protein | 25404640 |
| D020888 | Vigabatrin | [Pentylenetetrazole co-treated with Vigabatrin] affects the expression of PDK1 mRNA | 21503142 |
| D014750 | Vincristine | Vincristine results in decreased expression of PDK1 mRNA | 23649840 |
| C111237 | vorinostat | vorinostat inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 protein] | 26305601 |
| C111237 | vorinostat | vorinostat results in decreased expression of PDK1 mRNA | 27188386 |
| C017967 | W 7 | W 7 affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] | 28887310 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Dexamethasone results in increased phosphorylation of PDK1 protein] | 21655274 |
| D015032 | Zinc | Zinc deficiency results in increased expression of PDK1 mRNA | 18356318 |
| C016837 | zinc chloride | zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] | 22202117 |