Gene: SERPINF1

5176
EPC-1|OI12|OI6|PEDF|PIG35
serpin family F member 1
protein-coding
17p13.3
Ensembl:ENSG00000132386 MIM:172860 Vega:OTTHUMG00000090571 UniprotKB:P36955
NG_028180.1
PubMed
0   ANCO-SNPs
ND
5   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.504e-1 (AD)  7.165e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SEPT60.932
MICAL20.931
OPCML0.929
NUAK10.928
LDB20.928
MEF2C0.928
PAK10.927
SPATS20.922
PREP0.921
NELL20.921

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LRAT-0.561
HEY2-0.504
ASB4-0.49
YES1-0.488
RAI14-0.472
MBNL3-0.467
REST-0.467
ACAP1-0.463
MYOM1-0.457
AQP5-0.447

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB09130CopperSmall Molecule7440-50-8Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of SERPINF1 mRNA"19162173
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of SERPINF1 mRNA"23146750
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl affects the expression of SERPINF1 mRNA"19114083
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of SERPINF1 mRNA"25710175
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of SERPINF1 mRNA"21346803
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SERPINF1 mRNA"28973690
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in decreased expression of SERPINF1 mRNA"25912373
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of SERPINF1 mRNA29067470
D000082AcetaminophenAcetaminophen affects the expression of SERPINF1 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of SERPINF1 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SERPINF1 mRNA]17585979
D016604Aflatoxin B1Aflatoxin B1 affects the expression of SERPINF1 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SERPINF1 mRNA22100608|2715375
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SERPINF1 mRNA19770486
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of SERPINF1 mRNA28522335
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SERPINF1 mRNA16483693
D001280AtrazineAtrazine results in decreased expression of SERPINF1 mRNA22378314
C547126AZM551248AZM551248 results in increased expression of SERPINF1 mRNA22323515
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of SERPINF1 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SERPINF1 mRNA19770486
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in decreased expression of SERPINF1 mRNA25912373
C006780bisphenol Abisphenol A results in increased expression of SERPINF1 mRNA29275510
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SERPINF1 mRNA28628672
C006780bisphenol Abisphenol A results in decreased expression of SERPINF1 mRNA25181051
D002104CadmiumCadmium results in increased expression of SERPINF1 mRNA17327699
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of SERPINF1 mRNA21297351
D019256Cadmium ChlorideCadmium Chloride results in increased expression of SERPINF1 mRNA17327699
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINF1 mRNA20360939
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of SERPINF1 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of SERPINF1 mRNA27339419
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of SERPINF1 mRNA17585979
D002994ClofibrateClofibrate results in decreased expression of SERPINF1 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SERPINF1 mRNA]17585979
C018021cobaltous chloridecobaltous chloride affects the expression of SERPINF1 mRNA26800359
C018021cobaltous chloridecobaltous chloride results in decreased expression of SERPINF1 mRNA24386269
D003300CopperSERPINF1 protein binds to Copper23896426
D019327Copper SulfateCopper Sulfate results in decreased expression of SERPINF1 mRNA19549813
C029892cupric chloridecupric chloride results in increased expression of SERPINF1 mRNA17211630
D016572CyclosporineCyclosporine results in decreased expression of SERPINF1 mRNA20106945|2556210
C093628cyproconazolecyproconazole results in increased expression of SERPINF1 mRNA22664269
D013759DronabinolDronabinol results in decreased expression of SERPINF1 mRNA21955143
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of SERPINF1 mRNA]27941970
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SERPINF1 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SERPINF1 mRNA28628672
D003907DexamethasoneDexamethasone results in increased expression of SERPINF1 mRNA15051476
D003907DexamethasoneDexamethasone results in increased expression of SERPINF1 mRNA15051476
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of SERPINF1 mRNA21266533
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of SERPINF1 mRNA27392435
D002945CisplatinCisplatin results in increased expression of SERPINF1 mRNA27392435
D004041Dietary FatsDietary Fats results in decreased expression of SERPINF1 mRNA25016146
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of SERPINF1 mRNA21607683
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINF1 mRNA20360939
D002117CalcitriolCalcitriol results in decreased expression of SERPINF1 mRNA26485663
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in decreased expression of SERPINF1 mRNA27638505
D004237DiuronDiuron results in decreased expression of SERPINF1 mRNA25152437
D000431EthanolEthanol results in decreased expression of SERPINF1 mRNA21955143
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SERPINF1 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of SERPINF1 mRNA17557909
C540355fenamidonefenamidone results in increased expression of SERPINF1 mRNA27029645
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in decreased expression of SERPINF1 mRNA21607683
C061365flusilazoleflusilazole results in increased expression of SERPINF1 mRNA22664269|2826382
D005665FurosemideFurosemide affects the expression of SERPINF1 mRNA16526316
C419708gefitinibgefitinib inhibits the reaction [TGFA protein results in increased expression of SERPINF1 mRNA]18424623
D005897GlafenineGlafenine results in decreased expression of SERPINF1 mRNA24136188
D005947GlucoseGlucose deficiency results in decreased secretion of SERPINF1 protein24802182
D017313FenretinideFenretinide results in decreased expression of SERPINF1 mRNA28973697
C013038hydroxyhydroquinonehydroxyhydroquinone results in decreased expression of SERPINF1 mRNA17572062
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SERPINF1 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SERPINF1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SERPINF1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SERPINF1 mRNA28628672
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of SERPINF1 mRNA27392435
C544151jinfukangjinfukang results in increased expression of SERPINF1 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of SERPINF1 mRNA26644586
D048628KetolidesKetolides analog results in decreased expression of SERPINF1 mRNA24967691
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of SERPINF1 mRNA28001369
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of SERPINF1 mRNA24810058
C008493methylselenic acidmethylselenic acid results in increased expression of SERPINF1 mRNA18548127
D015735MifepristoneMifepristone results in decreased expression of SERPINF1 mRNA17584828
D015735MifepristoneMifepristone results in decreased expression of SERPINF1 mRNA25972201
D009020MorphineMorphine results in decreased expression of SERPINF1 mRNA21955143
C523799MRK 003MRK 003 results in increased expression of SERPINF1 mRNA21169257
C568376MT19c compoundMT19c compound results in decreased expression of SERPINF1 mRNA21781307
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SERPINF1 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SERPINF1 mRNA"25620056
C017096n-butoxyethanoln-butoxyethanol results in decreased expression of SERPINF1 mRNA19812364
C022838nickel chloridenickel chloride results in decreased expression of SERPINF1 mRNA24612858
D009538NicotineNicotine results in decreased expression of SERPINF1 mRNA26536586
D009538NicotineNicotine results in decreased expression of SERPINF1 protein26536586
D009538NicotineNicotine results in decreased expression of SERPINF1 mRNA21955143
C005311nornicotinenornicotine results in decreased expression of SERPINF1 mRNA26536586
C005311nornicotinenornicotine results in decreased expression of SERPINF1 protein26536586
C510784ormosil[ormosil binds to Polyethylene Glycols] which results in decreased expression of SERPINF1 mRNA24888373
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of SERPINF1 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of SERPINF1 mRNA25729387
D017239PaclitaxelPaclitaxel results in increased expression of SERPINF1 mRNA19682730
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
C496932panobinostatpanobinostat results in decreased expression of SERPINF1 mRNA26272509
C016030pantogabpantogab results in decreased expression of SERPINF1 mRNA17379144
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of SERPINF1 protein26879310
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of SERPINF1 mRNA19162173
C006253pirinixic acidpirinixic acid results in decreased expression of SERPINF1 mRNA19162173
D011092Polyethylene Glycols[ormosil binds to Polyethylene Glycols] which results in decreased expression of SERPINF1 mRNA24888373
D011192Potassium DichromatePotassium Dichromate results in increased expression of SERPINF1 mRNA11678601
D011374ProgesteroneProgesterone results in decreased expression of SERPINF1 mRNA23012394|2301818
D011374ProgesteroneProgesterone results in increased expression of SERPINF1 mRNA21795739
C513428pyrachlostrobinpyrachlostrobin results in increased expression of SERPINF1 mRNA27029645
D011794QuercetinQuercetin results in decreased expression of SERPINF1 mRNA21632981
C059514resveratrolresveratrol affects the secretion of SERPINF1 protein24802182
C089730rosiglitazonerosiglitazone results in decreased expression of SERPINF1 mRNA25572481
D012643SeleniumSelenium results in increased expression of SERPINF1 mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of SERPINF1 mRNA25895662
C017947sodium arsenitesodium arsenite results in increased expression of SERPINF1 protein23229538
D012999SomanSoman results in increased expression of SERPINF1 mRNA19281266
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in decreased expression of SERPINF1 mRNA"26680231
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SERPINF1 mRNA21570461|2637764
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SERPINF1 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SERPINF1 mRNA28238261
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SERPINF1 mRNA18465118|2121527
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SERPINF1 mRNA15644576
D019284ThapsigarginThapsigargin results in increased expression of SERPINF1 mRNA22378314
C009495titanium dioxidetitanium dioxide results in decreased expression of SERPINF1 mRNA23557971
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of SERPINF1 mRNA25729387
D019772TopotecanTopotecan results in increased expression of SERPINF1 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of SERPINF1 mRNA"19682533
D014212TretinoinTretinoin results in increased expression of SERPINF1 mRNA15051476
D014212TretinoinTretinoin results in increased expression of SERPINF1 protein15051476
D014212TretinoinTretinoin results in decreased expression of SERPINF1 mRNA23724009
D014212TretinoinTretinoin results in increased expression of SERPINF1 mRNA15051476
D014212TretinoinTretinoin results in increased expression of SERPINF1 protein15051476
D014212TretinoinTretinoin results in increased expression of SERPINF1 mRNA15051476
D014212TretinoinTretinoin results in increased expression of SERPINF1 mRNA15051476|2048824
C032910triadimefontriadimefon results in increased expression of SERPINF1 mRNA22664269
D014241TrichloroethyleneTrichloroethylene affects the expression of SERPINF1 mRNA21135412
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of SERPINF1 mRNA24935251|2627250
C012589trichostatin Atrichostatin A results in decreased expression of SERPINF1 mRNA15901671
C057693troglitazonetroglitazone results in decreased expression of SERPINF1 mRNA25572481
C057693troglitazonetroglitazone results in increased expression of SERPINF1 mRNA28973697
D014415TunicamycinTunicamycin results in increased expression of SERPINF1 mRNA22378314
C406224valdecoxibvaldecoxib results in decreased expression of SERPINF1 mRNA24136188
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERPINF1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of SERPINF1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of SERPINF1 mRNA19101580|2317975
D014635Valproic AcidValproic Acid results in decreased expression of SERPINF1 mRNA21427059
D014635Valproic AcidValproic Acid results in increased expression of SERPINF1 mRNA24896083
D014635Valproic AcidValproic Acid results in decreased expression of SERPINF1 mRNA15901671
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of SERPINF1 gene25487561
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of SERPINF1 gene25560391
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of SERPINF1 mRNA19165385
C029297vinylidene chloridevinylidene chloride results in increased expression of SERPINF1 mRNA26682919
D014810Vitamin EVitamin E results in increased expression of SERPINF1 mRNA19244175
C111237vorinostatvorinostat results in decreased expression of SERPINF1 mRNA18769122

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004867serine-type endopeptidase inhibitor activity-IBA21873635  
GO:0004867serine-type endopeptidase inhibitor activity-TAS8473338  
GO:0005515protein binding-IPI25416956  25910212  
GO ID GO Term Qualifier Evidence PubMed
GO:0001822kidney development-IEA-  
GO:0007275multicellular organism development-TAS8473338  
GO:0007568aging-IEA-  
GO:0007614short-term memory-IEA-  
GO:0008283cell proliferation-TAS8473338  
GO:0010447response to acidic pH-IEA-  
GO:0010596negative regulation of endothelial cell migration-IEA-  
GO:0010629negative regulation of gene expression-IEA-  
GO:0010951negative regulation of endopeptidase activity-IBA21873635  
GO:0010951negative regulation of endopeptidase activity-IEA-  
GO:0010976positive regulation of neuron projection development-IEA-  
GO:0016525negative regulation of angiogenesis-IDA11562499  
GO:0042698ovulation cycle-IEA-  
GO:0046685response to arsenic-containing substance-IEA-  
GO:0050728negative regulation of inflammatory response-IEA-  
GO:0050769positive regulation of neurogenesis-IDA8226833  
GO:0060041retina development in camera-type eye-IEA-  
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland development-IEA-  
GO:0071279cellular response to cobalt ion-IEA-  
GO:0071300cellular response to retinoic acid-IEA-  
GO:0071333cellular response to glucose stimulus-IEA-  
GO:0071549cellular response to dexamethasone stimulus-IEA-  
GO:1901215negative regulation of neuron death-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IDA12737624  
GO:0005604basement membrane-IEA-  
GO:0005615extracellular space-HDA20551380  
GO:0005615extracellular space-IBA21873635  
GO:0042470melanosome-IEA-  
GO:0043203axon hillock-IEA-  
GO:0048471perinuclear region of cytoplasm-IEA-  
GO:0062023collagen-containing extracellular matrixcolocalizes_withHDA20551380  
GO:0070062extracellular exosome-HDA19056867  23533145  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
17409975Establishment and expression profiling of new lung cancer cell lines from Chinese smokers and lifetime never-smokers. (2006 Nov)Lam DCJ Thorac Oncol
28926193Association between CFH, CFB, ARMS2, SERPINF1, VEGFR1 and VEGF polymorphisms and anatomical and functional response to ranibizumab treatment in neovascular age-related macular degeneration. (2018 Mar)Cobos EActa Ophthalmol
28562170Pigment epithelial-derived factor in human fetal membranes. (2018 Aug)Stalberg CJ Matern Fetal Neonatal Med
22430805Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study. (2012 Mar)Langevin SMEpigenetics
21439646Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy. (2011 Jul)Nakata IOphthalmology