Gene info: ID 5243

Gene: ABCB1

GENE ID: 5243

Synonyms: ABC20|CD243|CLCS|GP170|MDR1|P-GP|PGY1

Description: ATP binding cassette subfamily B member 1

Gene type: protein-coding

Location: 7q21.12

dbXrefs: Ensembl:ENSG00000085563 MIM:171050 Vega:OTTHUMG00000023393 UniprotKB:P08183

RefSeq: NG_011513.1

Retrived from: PubMed|SNP Mapped

SNPs: 2 ANCO-SNPs

Phenotype: CD|OD|ND|AD

# Publications: 40

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 2.743e-1 (AD) 5.851e-1 (ND)

ANCO-SNPs

SNP ID	Position	Alleles	Trait	Variation Type
rs4728701	chr7:87542737 (GRCh38.p7)	A>G	alcohol dependence	SNV(Single Nucleotide Variation)
rs4728699	chr7:87539433 (GRCh38.p7)	C>T	alcohol dependence	SNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
A2M	0.905
EMCN	0.888
PTPRB	0.888
CYYR1	0.884
TGFBR2	0.864
MYCT1	0.855
ABCG2	0.851
LEF1	0.842
FLT1	0.835
SLC19A3	0.834

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
C1orf53	-0.361
TMEM121	-0.36
GGN	-0.355
C16orf95	-0.355
ASPDH	-0.351
CHST8	-0.35
MESP1	-0.344
LYPD8	-0.34
TEPP	-0.335
CRH	-0.332

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00027	Gramicidin D	Small Molecule	1405-97-6	Approved	Transporter
DB00091	Cyclosporine	Small Molecule	59865-13-3	Approved\|Investigational	Transporter
DB00175	Pravastatin	Small Molecule	81093-37-0	Approved	Transporter
DB00176	Fluvoxamine	Small Molecule	54739-18-3	Approved\|Investigational	Transporter
DB00196	Fluconazole	Small Molecule	86386-73-4	Approved\|Investigational	Transporter
DB00199	Erythromycin	Small Molecule	114-07-8	Approved\|Investigational	Transporter
DB00201	Caffeine	Small Molecule	58-08-2	Approved	Transporter
DB00206	Reserpine	Small Molecule	50-55-5	Approved\|Investigational	Transporter
DB00207	Azithromycin	Small Molecule	83905-01-5	Approved	Transporter
DB00213	Pantoprazole	Small Molecule	102625-70-7	Approved	Transporter
DB00215	Citalopram	Small Molecule	59729-33-8	Approved	Transporter
DB00216	Eletriptan	Small Molecule	143322-58-1	Approved\|Investigational	Transporter
DB00220	Nelfinavir	Small Molecule	159989-64-7	Approved	Transporter
DB00224	Indinavir	Small Molecule	150378-17-9	Approved	Transporter
DB00227	Lovastatin	Small Molecule	75330-75-5	Approved\|Investigational	Transporter
DB00234	Reboxetine	Small Molecule	71620-89-8	Approved\|Investigational	Transporter
DB00252	Phenytoin	Small Molecule	57-41-0	Approved	Transporter
DB00255	Diethylstilbestrol	Small Molecule	56-53-1	Approved\|Investigational	Transporter
DB00257	Clotrimazole	Small Molecule	23593-75-1	Approved	Transporter
DB00264	Metoprolol	Small Molecule	51384-51-1	Approved\|Investigational	Transporter
DB00276	Amsacrine	Small Molecule	51264-14-3	Approved\|Investigational	Transporter
DB00279	Liothyronine	Small Molecule	6893-02-3	Approved	Transporter
DB00281	Lidocaine	Small Molecule	137-58-6	Approved	Transporter
DB00285	Venlafaxine	Small Molecule	93413-69-5	Approved	Transporter
DB00286	Conjugated estrogens	Small Molecule	12126-59-9	Approved	Transporter
DB00295	Morphine	Small Molecule	57-27-2	Approved\|Investigational	Transporter
DB00305	Mitomycin	Small Molecule	50-07-7	Approved	Transporter
DB00316	Acetaminophen	Small Molecule	103-90-2	Approved	Transporter
DB00317	Gefitinib	Small Molecule	184475-35-2	Approved\|Investigational	Transporter
DB00320	Dihydroergotamine	Small Molecule	511-12-6	Approved\|Investigational	Transporter
DB00321	Amitriptyline	Small Molecule	50-48-6	Approved	Transporter
DB00328	Indomethacin	Small Molecule	53-86-1	Approved\|Investigational	Transporter
DB00333	Methadone	Small Molecule	76-99-3	Approved	Transporter
DB00334	Olanzapine	Small Molecule	132539-06-1	Approved\|Investigational	Transporter
DB00335	Atenolol	Small Molecule	29122-68-7	Approved	Transporter
DB00338	Omeprazole	Small Molecule	73590-58-6	Approved\|Investigational	Transporter
DB00342	Terfenadine	Small Molecule	50679-08-8	Approved\|Withdrawn	Transporter
DB00343	Diltiazem	Small Molecule	42399-41-7	Approved\|Investigational	Transporter
DB00344	Protriptyline	Small Molecule	438-60-8	Approved	Transporter
DB00345	Aminohippuric acid	Small Molecule	61-78-9	Approved\|Investigational	Transporter
DB00349	Clobazam	Small Molecule	22316-47-8	Approved\|Illicit	Transporter
DB00351	Megestrol acetate	Small Molecule	595-33-5	Approved\|Investigational	Transporter
DB00358	Mefloquine	Small Molecule	53230-10-7	Approved\|Investigational	Transporter
DB00361	Vinorelbine	Small Molecule	71486-22-1	Approved\|Investigational	Transporter
DB00363	Clozapine	Small Molecule	5786-21-0	Approved	Transporter
DB00365	Grepafloxacin	Small Molecule	119914-60-2	Approved\|Investigational\|Withdrawn	Transporter
DB00371	Meprobamate	Small Molecule	57-53-4	Approved\|Illicit	Transporter
DB00373	Timolol	Small Molecule	26839-75-8	Approved	Transporter
DB00381	Amlodipine	Small Molecule	88150-42-9	Approved	Transporter
DB00382	Tacrine	Small Molecule	321-64-2	Investigational\|Withdrawn	Transporter
DB00390	Digoxin	Small Molecule	20830-75-5	Approved	Transporter
DB00396	Progesterone	Small Molecule	57-83-0	Approved	Transporter
DB00398	Sorafenib	Small Molecule	284461-73-0	Approved\|Investigational	Transporter
DB00401	Nisoldipine	Small Molecule	63675-72-9	Approved	Transporter
DB00421	Spironolactone	Small Molecule	52-01-7	Approved	Transporter
DB00428	Streptozocin	Small Molecule	18883-66-4	Approved\|Investigational	Transporter
DB00439	Cerivastatin	Small Molecule	145599-86-6	Approved\|Withdrawn	Transporter
DB00440	Trimethoprim	Small Molecule	738-70-5	Approved	Transporter
DB00441	Gemcitabine	Small Molecule	95058-81-4	Approved	Transporter
DB00443	Betamethasone	Small Molecule	378-44-9	Approved	Transporter
DB00448	Lansoprazole	Small Molecule	103577-45-3	Approved\|Investigational	Transporter
DB00451	Levothyroxine	Small Molecule	51-48-9	Approved	Transporter
DB00455	Loratadine	Small Molecule	79794-75-5	Approved\|Investigational	Transporter
DB00457	Prazosin	Small Molecule	19216-56-9	Approved	Transporter
DB00458	Imipramine	Small Molecule	50-49-7	Approved	Transporter
DB00468	Quinine	Small Molecule	130-95-0	Approved	Transporter
DB00470	Dronabinol	Small Molecule	1972-08-3	Approved\|Illicit	Transporter
DB00472	Fluoxetine	Small Molecule	54910-89-3	Approved	Transporter
DB00477	Chlorpromazine	Small Molecule	50-53-3	Approved\|Investigational	Transporter
DB00480	Lenalidomide	Small Molecule	191732-72-6	Approved	Transporter
DB00490	Buspirone	Small Molecule	36505-84-7	Approved\|Investigational	Transporter
DB00495	Zidovudine	Small Molecule	30516-87-1	Approved	Transporter
DB00501	Cimetidine	Small Molecule	51481-61-9	Approved\|Investigational	Transporter
DB00502	Haloperidol	Small Molecule	52-86-8	Approved	Transporter
DB00503	Ritonavir	Small Molecule	155213-67-5	Approved\|Investigational	Transporter
DB00508	Triflupromazine	Small Molecule	146-54-3	Approved	Transporter
DB00514	Dextromethorphan	Small Molecule	125-71-3	Approved	Transporter
DB00515	Cisplatin	Small Molecule	15663-27-1	Approved	Transporter
DB00518	Albendazole	Small Molecule	54965-21-8	Approved	Transporter
DB00520	Caspofungin	Small Molecule	162808-62-0	Approved	Transporter
DB00523	Alitretinoin	Small Molecule	5300-03-8	Approved\|Investigational	Transporter
DB00530	Erlotinib	Small Molecule	183321-74-6	Approved\|Investigational	Transporter
DB00531	Cyclophosphamide	Small Molecule	50-18-0	Approved\|Investigational	Transporter
DB00537	Ciprofloxacin	Small Molecule	85721-33-1	Approved\|Investigational	Transporter
DB00539	Toremifene	Small Molecule	89778-26-7	Approved\|Investigational	Transporter
DB00541	Vincristine	Small Molecule	57-22-7	Approved\|Investigational	Transporter
DB00555	Lamotrigine	Small Molecule	84057-84-1	Approved\|Investigational	Transporter
DB00563	Methotrexate	Small Molecule	59-05-2	Approved	Transporter
DB00564	Carbamazepine	Small Molecule	298-46-4	Approved\|Investigational	Transporter
DB00570	Vinblastine	Small Molecule	865-21-4	Approved	Transporter
DB00571	Propranolol	Small Molecule	525-66-6	Approved\|Investigational	Transporter
DB00575	Clonidine	Small Molecule	4205-90-7	Approved	Transporter
DB00584	Enalapril	Small Molecule	75847-73-3	Approved	Transporter
DB00585	Nizatidine	Small Molecule	76963-41-2	Approved	Transporter
DB00586	Diclofenac	Small Molecule	15307-86-5	Approved	Transporter
DB00590	Doxazosin	Small Molecule	74191-85-8	Approved	Transporter
DB00602	Ivermectin	Small Molecule	70288-86-7	Approved\|Investigational	Transporter
DB00608	Chloroquine	Small Molecule	54-05-7	Approved\|Investigational	Transporter
DB00619	Imatinib	Small Molecule	152459-95-5	Approved	Transporter
DB00622	Nicardipine	Small Molecule	55985-32-5	Approved\|Investigational	Transporter
DB00623	Fluphenazine	Small Molecule	69-23-8	Approved	Transporter
DB00624	Testosterone	Small Molecule	58-22-0	Approved\|Investigational	Transporter
DB00635	Prednisone	Small Molecule	53-03-2	Approved	Transporter
DB00637	Astemizole	Small Molecule	68844-77-9	Approved\|Withdrawn	Transporter
DB00641	Simvastatin	Small Molecule	79902-63-9	Approved	Transporter
DB00643	Mebendazole	Small Molecule	31431-39-7	Approved	Transporter
DB00655	Estrone	Small Molecule	53-16-7	Approved	Transporter
DB00656	Trazodone	Small Molecule	19794-93-5	Approved\|Investigational	Transporter
DB00661	Verapamil	Small Molecule	52-53-9	Approved	Transporter
DB00669	Sumatriptan	Small Molecule	103628-46-2	Approved\|Investigational	Transporter
DB00672	Chlorpropamide	Small Molecule	94-20-2	Approved\|Investigational	Transporter
DB00675	Tamoxifen	Small Molecule	10540-29-1	Approved	Transporter
DB00678	Losartan	Small Molecule	114798-26-4	Approved	Transporter
DB00683	Midazolam	Small Molecule	59467-70-8	Approved\|Illicit	Transporter
DB00688	Mycophenolate mofetil	Small Molecule	128794-94-5	Approved\|Investigational	Transporter
DB00690	Flurazepam	Small Molecule	17617-23-1	Approved\|Illicit\|Investigational	Transporter
DB00694	Daunorubicin	Small Molecule	20830-81-3	Approved	Transporter
DB00696	Ergotamine	Small Molecule	113-15-5	Approved	Transporter
DB00701	Amprenavir	Small Molecule	161814-49-9	Approved\|Investigational	Transporter
DB00704	Naltrexone	Small Molecule	16590-41-3	Approved\|Investigational	Transporter
DB00709	Lamivudine	Small Molecule	134678-17-4	Approved\|Investigational	Transporter
DB00715	Paroxetine	Small Molecule	61869-08-7	Approved\|Investigational	Transporter
DB00717	Norethisterone	Small Molecule	68-22-4	Approved	Transporter
DB00726	Trimipramine	Small Molecule	739-71-9	Approved	Transporter
DB00741	Hydrocortisone	Small Molecule	50-23-7	Approved	Transporter
DB00742	Mannitol	Small Molecule	69-65-8	Approved\|Investigational	Transporter
DB00747	Scopolamine	Small Molecule	51-34-3	Approved\|Investigational	Transporter
DB00751	Epinastine	Small Molecule	80012-43-7	Approved\|Investigational	Transporter
DB00758	Clopidogrel	Small Molecule	113665-84-2	Approved	Transporter
DB00762	Irinotecan	Small Molecule	97682-44-5	Approved\|Investigational	Transporter
DB00773	Etoposide	Small Molecule	33419-42-0	Approved	Transporter
DB00783	Estradiol	Small Molecule	50-28-2	Approved\|Investigational	Transporter
DB00790	Perindopril	Small Molecule	82834-16-0	Approved	Transporter
DB00796	Candesartan cilexetil	Small Molecule	145040-37-5	Approved	Transporter
DB00802	Alfentanil	Small Molecule	71195-58-9	Approved\|Illicit	Transporter
DB00810	Biperiden	Small Molecule	514-65-8	Approved\|Investigational	Transporter
DB00813	Fentanyl	Small Molecule	437-38-7	Approved\|Illicit\|Investigational	Transporter
DB00829	Diazepam	Small Molecule	439-14-5	Approved\|Illicit\|Investigational	Transporter
DB00831	Trifluoperazine	Small Molecule	117-89-5	Approved\|Investigational	Transporter
DB00834	Mifepristone	Small Molecule	84371-65-3	Approved\|Investigational	Transporter
DB00836	Loperamide	Small Molecule	53179-11-6	Approved	Transporter
DB00845	Clofazimine	Small Molecule	2030-63-9	Approved\|Investigational	Transporter
DB00860	Prednisolone	Small Molecule	50-24-8	Approved	Transporter
DB00863	Ranitidine	Small Molecule	66357-35-5	Approved	Transporter
DB00864	Tacrolimus	Small Molecule	104987-11-3	Approved\|Investigational	Transporter
DB00875	Flupentixol	Small Molecule	2709-56-0	Approved\|Investigational\|Withdrawn	Transporter
DB00877	Sirolimus	Small Molecule	53123-88-9	Approved\|Investigational	Transporter
DB00882	Clomifene	Small Molecule	911-45-5	Approved\|Investigational	Transporter
DB00908	Quinidine	Small Molecule	56-54-2	Approved\|Investigational	Transporter
DB00915	Amantadine	Small Molecule	768-94-5	Approved	Transporter
DB00921	Buprenorphine	Small Molecule	52485-79-7	Approved\|Illicit\|Investigational	Transporter
DB00934	Maprotiline	Small Molecule	10262-69-8	Approved\|Investigational	Transporter
DB00936	Salicylic acid	Small Molecule	69-72-7	Approved\|Investigational	Transporter
DB00945	Acetylsalicylic acid	Small Molecule	50-78-2	Approved	Transporter
DB00950	Fexofenadine	Small Molecule	83799-24-0	Approved\|Investigational	Transporter
DB00959	Methylprednisolone	Small Molecule	83-43-2	Approved	Transporter
DB00966	Telmisartan	Small Molecule	144701-48-4	Approved\|Investigational	Transporter
DB00967	Desloratadine	Small Molecule	100643-71-8	Approved\|Investigational	Transporter
DB00970	Dactinomycin	Small Molecule	50-76-0	Approved\|Investigational	Transporter
DB00972	Azelastine	Small Molecule	58581-89-8	Approved	Transporter
DB00973	Ezetimibe	Small Molecule	163222-33-1	Approved	Transporter
DB00975	Dipyridamole	Small Molecule	58-32-2	Approved	Transporter
DB00977	Ethinyl Estradiol	Small Molecule	57-63-6	Approved	Transporter
DB00997	Doxorubicin	Small Molecule	23214-92-8	Approved\|Investigational	Transporter
DB01016	Glyburide	Small Molecule	10238-21-8	Approved	Transporter
DB01023	Felodipine	Small Molecule	72509-76-3	Approved\|Investigational	Transporter
DB01026	Ketoconazole	Small Molecule	65277-42-1	Approved\|Investigational	Transporter
DB01030	Topotecan	Small Molecule	123948-87-8	Approved\|Investigational	Transporter
DB01032	Probenecid	Small Molecule	57-66-9	Approved\|Investigational	Transporter
DB01037	Selegiline	Small Molecule	14611-51-9	Approved\|Investigational	Transporter
DB01045	Rifampicin	Small Molecule	13292-46-1	Approved	Transporter
DB01050	Ibuprofen	Small Molecule	15687-27-1	Approved	Transporter
DB01054	Nitrendipine	Small Molecule	39562-70-4	Approved\|Investigational	Transporter
DB01069	Promethazine	Small Molecule	60-87-7	Approved\|Investigational	Transporter
DB01072	Atazanavir	Small Molecule	198904-31-3	Approved\|Investigational	Transporter
DB01076	Atorvastatin	Small Molecule	134523-00-5	Approved	Transporter
DB01086	Benzocaine	Small Molecule	94-09-7	Approved\|Investigational	Transporter
DB01100	Pimozide	Small Molecule	2062-78-4	Approved	Transporter
DB01103	Quinacrine	Small Molecule	83-89-6	Approved\|Investigational	Transporter
DB01104	Sertraline	Small Molecule	79617-96-2	Approved	Transporter
DB01110	Miconazole	Small Molecule	22916-47-8	Approved\|Investigational	Transporter
DB01115	Nifedipine	Small Molecule	21829-25-4	Approved	Transporter
DB01118	Amiodarone	Small Molecule	1951-25-3	Approved\|Investigational	Transporter
DB01136	Carvedilol	Small Molecule	72956-09-3	Approved\|Investigational	Transporter
DB01137	Levofloxacin	Small Molecule	100986-85-4	Approved\|Investigational	Transporter
DB01138	Sulfinpyrazone	Small Molecule	57-96-5	Approved	Transporter
DB01142	Doxepin	Small Molecule	1668-19-5	Approved\|Investigational	Transporter
DB01149	Nefazodone	Small Molecule	83366-66-9	Approved\|Withdrawn	Transporter
DB01151	Desipramine	Small Molecule	50-47-5	Approved\|Investigational	Transporter
DB01162	Terazosin	Small Molecule	63590-64-7	Approved	Transporter
DB01167	Itraconazole	Small Molecule	84625-61-6	Approved\|Investigational	Transporter
DB01169	Arsenic trioxide	Small Molecule	1327-53-3	Approved\|Investigational	Transporter
DB01174	Phenobarbital	Small Molecule	50-06-6	Approved\|Investigational	Transporter
DB01182	Propafenone	Small Molecule	54063-53-5	Approved	Transporter
DB01183	Naloxone	Small Molecule	465-65-6	Approved	Transporter
DB01184	Domperidone	Small Molecule	57808-66-9	Approved\|Investigational	Transporter
DB01193	Acebutolol	Small Molecule	37517-30-9	Approved\|Investigational	Transporter
DB01196	Estramustine	Small Molecule	2998-57-4	Approved\|Investigational	Transporter
DB01197	Captopril	Small Molecule	62571-86-2	Approved	Transporter
DB01200	Bromocriptine	Small Molecule	25614-03-3	Approved\|Investigational	Transporter
DB01202	Levetiracetam	Small Molecule	102767-28-2	Approved\|Investigational	Transporter
DB01203	Nadolol	Small Molecule	42200-33-9	Approved	Transporter
DB01204	Mitoxantrone	Small Molecule	65271-80-9	Approved\|Investigational	Transporter
DB01208	Sparfloxacin	Small Molecule	110871-86-8	Approved\|Investigational	Transporter
DB01211	Clarithromycin	Small Molecule	81103-11-9	Approved	Transporter
DB01221	Ketamine	Small Molecule	6740-88-1	Approved	Transporter
DB01224	Quetiapine	Small Molecule	111974-69-7	Approved	Transporter
DB01229	Paclitaxel	Small Molecule	33069-62-4	Approved	Transporter
DB01232	Saquinavir	Small Molecule	127779-20-8	Approved\|Investigational	Transporter
DB01234	Dexamethasone	Small Molecule	50-02-2	Approved\|Investigational	Transporter
DB01239	Chlorprothixene	Small Molecule	113-59-7	Approved\|Investigational\|Withdrawn	Transporter
DB01242	Clomipramine	Small Molecule	303-49-1	Approved\|Investigational	Transporter
DB01244	Bepridil	Small Molecule	64706-54-3	Approved\|Withdrawn	Transporter
DB01248	Docetaxel	Small Molecule	114977-28-5	Approved\|Investigational	Transporter
DB01253	Ergonovine	Small Molecule	60-79-7	Approved	Transporter
DB01254	Dasatinib	Small Molecule	302962-49-8	Approved\|Investigational	Transporter
DB01259	Lapatinib	Small Molecule	231277-92-2	Approved\|Investigational	Transporter
DB01261	Sitagliptin	Small Molecule	486460-32-6	Approved\|Investigational	Transporter
DB01263	Posaconazole	Small Molecule	171228-49-2	Approved\|Investigational	Transporter
DB01268	Sunitinib	Small Molecule	557795-19-4	Approved\|Investigational	Transporter
DB01323	St. John's Wort	Small Molecule	84082-80-4	Approved\|Investigational\|Nutraceutical	Transporter
DB01339	Vecuronium	Small Molecule	86029-43-8	Approved	Transporter
DB01340	Cilazapril	Small Molecule	88768-40-5	Approved	Transporter
DB01388	Mibefradil	Small Molecule	116644-53-2	Investigational\|Withdrawn	Transporter
DB01394	Colchicine	Small Molecule	64-86-8	Approved	Transporter
DB01396	Digitoxin	Small Molecule	71-63-6	Approved\|Investigational	Transporter
DB01400	Neostigmine	Small Molecule	59-99-4	Approved	Transporter
DB01420	Testosterone propionate	Small Molecule	57-85-2	Approved\|Investigational\|Withdrawn	Transporter
DB01583	Liotrix	Small Molecule	8065-29-0	Approved	Transporter
DB01587	Ketazolam	Small Molecule	27223-35-4	Approved	Transporter
DB01595	Nitrazepam	Small Molecule	146-22-5	Approved	Transporter
DB01601	Lopinavir	Small Molecule	192725-17-0	Approved	Transporter
DB01645	Genistein	Small Molecule	446-72-0	Investigational	Transporter
DB02010	Staurosporine	Small Molecule	62996-74-1	Experimental	Transporter
DB02261	Platelet Activating Factor	Small Molecule	74389-68-7	Experimental	Transporter
DB02587	Colforsin	Small Molecule	66575-29-9	Experimental\|Investigational	Transporter
DB02659	Cholic Acid	Small Molecule	81-25-4	Approved	Transporter
DB02901	Stanolone	Small Molecule	521-18-6	Illicit\|Investigational	Transporter
DB03203	Sphingosine	Small Molecule	123-78-4	Experimental	Transporter
DB03467	Naringenin	Small Molecule	480-41-1	Experimental	Transporter
DB03796	Palmitic Acid	Small Molecule	57-10-3	Approved\|Experimental	Transporter
DB04216	Quercetin	Small Molecule	117-39-5	Experimental\|Investigational	Transporter
DB04348	Taurocholic Acid	Small Molecule	81-24-3	Experimental	Transporter
DB04417	P-Nitrophenol	Small Molecule	100-02-7	Experimental	Transporter
DB04540	Cholesterol	Small Molecule	57-88-5	Approved\|Experimental\|Investigational	Transporter
DB04573	Estriol	Small Molecule	50-27-1	Approved\|Investigational	Transporter
DB04630	Aldosterone	Small Molecule	52-39-1	Experimental\|Investigational	Transporter
DB04690	Camptothecin	Small Molecule	7689-03-4	Experimental	Transporter
DB04832	Zimelidine	Small Molecule	56775-88-3	Withdrawn	Transporter
DB04840	Debrisoquin	Small Molecule	1131-64-2	Approved\|Investigational	Transporter
DB04855	Dronedarone	Small Molecule	141626-36-0	Approved	Transporter
DB04868	Nilotinib	Small Molecule	641571-10-0	Approved\|Investigational	Transporter
DB05015	Belinostat	Small Molecule	866323-14-0	Approved\|Investigational	Transporter
DB05039	Indacaterol	Small Molecule	312753-06-3	Approved	Transporter
DB05521	Telaprevir	Small Molecule	402957-28-2	Approved\|Withdrawn	Transporter
DB05773	Trastuzumab emtansine	BiotechDrug	1018448-65-1	Approved\|Investigational	Transporter
DB05889	Inotuzumab ozogamicin	BiotechDrug	635715-01-4	Approved\|Investigational	Transporter
DB06176	Romidepsin	Small Molecule	128517-07-7	Approved\|Investigational	Transporter
DB06207	Silodosin	Small Molecule	160970-54-7	Approved	Transporter
DB06212	Tolvaptan	Small Molecule	150683-30-0	Approved	Transporter
DB06228	Rivaroxaban	Small Molecule	366789-02-8	Approved	Transporter
DB06287	Temsirolimus	Small Molecule	162635-04-3	Approved	Transporter
DB06290	Simeprevir	Small Molecule	923604-59-5	Approved	Transporter
DB06292	Dapagliflozin	Small Molecule	461432-26-8	Approved	Transporter
DB06403	Ambrisentan	Small Molecule	177036-94-1	Approved\|Investigational	Transporter
DB06414	Etravirine	Small Molecule	269055-15-4	Approved	Transporter
DB06589	Pazopanib	Small Molecule	444731-52-6	Approved	Transporter
DB06603	Panobinostat	Small Molecule	404950-80-7	Approved\|Investigational	Transporter
DB06605	Apixaban	Small Molecule	503612-47-3	Approved	Transporter
DB06616	Bosutinib	Small Molecule	380843-75-4	Approved	Transporter
DB06626	Axitinib	Small Molecule	319460-85-0	Approved\|Investigational	Transporter
DB06636	Isavuconazonium	Small Molecule	742049-41-8	Approved\|Investigational	Transporter
DB06695	Dabigatran etexilate	Small Molecule	211915-06-9	Approved	Transporter
DB06702	Fesoterodine	Small Molecule	286930-02-7	Approved	Transporter
DB06772	Cabazitaxel	Small Molecule	183133-96-2	Approved	Transporter
DB08816	Ticagrelor	Small Molecule	274693-27-5	Approved	Transporter
DB08820	Ivacaftor	Small Molecule	873054-44-5	Approved	Transporter
DB08827	Lomitapide	Small Molecule	182431-12-5	Approved\|Investigational	Transporter
DB08828	Vismodegib	Small Molecule	879085-55-9	Approved\|Investigational	Transporter
DB08860	Pitavastatin	Small Molecule	147511-69-1	Approved	Transporter
DB08864	Rilpivirine	Small Molecule	500287-72-9	Approved	Transporter
DB08865	Crizotinib	Small Molecule	877399-52-5	Approved	Transporter
DB08867	Ulipristal	Small Molecule	159811-51-5	Approved	Transporter
DB08873	Boceprevir	Small Molecule	394730-60-0	Approved\|Withdrawn	Transporter
DB08874	Fidaxomicin	Small Molecule	873857-62-6	Approved	Transporter
DB08882	Linagliptin	Small Molecule	668270-12-0	Approved	Transporter
DB08889	Carfilzomib	Small Molecule	868540-17-4	Approved\|Investigational	Transporter
DB08893	Mirabegron	Small Molecule	223673-61-8	Approved	Transporter
DB08896	Regorafenib	Small Molecule	755037-03-7	Approved	Transporter
DB08899	Enzalutamide	Small Molecule	915087-33-1	Approved	Transporter
DB08901	Ponatinib	Small Molecule	943319-70-8	Approved\|Investigational	Transporter
DB08906	Fluticasone furoate	Small Molecule	397864-44-7	Approved	Transporter
DB08907	Canagliflozin	Small Molecule	842133-18-0	Approved	Transporter
DB08910	Pomalidomide	Small Molecule	19171-19-8	Approved	Transporter
DB08912	Dabrafenib	Small Molecule	-	Approved\|Investigational	Transporter
DB08916	Afatinib	Small Molecule	850140-72-6	Approved	Transporter
DB08918	Levomilnacipran	Small Molecule	96847-54-0	Approved\|Investigational	Transporter
DB08934	Sofosbuvir	Small Molecule	1190307-88-0	Approved	Transporter
DB09027	Ledipasvir	Small Molecule	1256388-51-8	Approved	Transporter
DB09054	Idelalisib	Small Molecule	870281-82-6	Approved	Transporter
DB09063	Ceritinib	Small Molecule	1032900-25-6	Approved	Transporter
DB09065	Cobicistat	Small Molecule	1004316-88-4	Approved	Transporter
DB09075	Edoxaban	Small Molecule	480449-70-5	Approved	Transporter
DB09076	Umeclidinium	Small Molecule	869185-19-3	Approved	Transporter
DB09078	Lenvatinib	Small Molecule	417716-92-8	Approved\|Investigational	Transporter
DB09079	Nintedanib	Small Molecule	656247-17-5	Approved	Transporter
DB09102	Daclatasvir	Small Molecule	1009119-64-5	Approved\|Investigational	Transporter
DB09161	Technetium Tc-99m sestamibi	Small Molecule	109581-73-9	Approved\|Investigational	Transporter
DB09198	Lobeglitazone	Small Molecule	607723-33-1	Approved\|Investigational	Transporter
DB09231	Benidipine	Small Molecule	105979-17-7	Approved\|Investigational	Transporter
DB09270	Ubidecarenone	Small Molecule	303-98-0	Approved\|Investigational\|Nutraceutical	Transporter
DB09280	Lumacaftor	Small Molecule	936727-05-8	Approved	Transporter
DB09291	Rolapitant	Small Molecule	552292-08-7	Approved\|Investigational	Transporter
DB09296	Ombitasvir	Small Molecule	1258226-87-7	Approved\|Investigational	Transporter
DB09330	Osimertinib	Small Molecule	1421373-65-0	Approved	Transporter
DB09462	Glycerin	Small Molecule	56-81-5	Approved\|Investigational	Transporter
DB11362	Selexipag	Small Molecule	475086-01-2	Approved	Transporter
DB11574	Elbasvir	Small Molecule	1370468-36-2	Approved	Transporter
DB11575	Grazoprevir	Small Molecule	1350514-68-9	Approved	Transporter
DB11581	Venetoclax	Small Molecule	1257044-40-8	Approved\|Investigational	Transporter
DB11613	Velpatasvir	Small Molecule	1377049-84-7	Approved\|Investigational	Transporter
DB11633	Isavuconazole	Small Molecule	241479-67-4	Approved\|Investigational	Transporter
DB11817	Baricitinib	Small Molecule	1187594-09-7	Approved\|Investigational	Transporter
DB11827	Ertugliflozin	Small Molecule	1210344-57-2	Approved\|Investigational	Transporter
DB11901	Apalutamide	Small Molecule	956104-40-8	Approved\|Investigational	Transporter
DB12001	Abemaciclib	Small Molecule	1231929-97-7	Approved\|Investigational	Transporter
DB12026	Voxilaprevir	Small Molecule	1535212-07-7	Approved\|Investigational	Transporter
DB12070	Letermovir	Small Molecule	917389-32-3	Approved\|Investigational	Transporter
DB12332	Rucaparib	Small Molecule	283173-50-2	Approved\|Investigational	Transporter
DB12364	Betrixaban	Small Molecule	330942-05-7	Approved\|Investigational	Transporter
DB12483	Copanlisib	Small Molecule	1032568-63-0	Approved\|Investigational	Transporter
DB13146	Fluciclovine (18F)	Small Molecule	222727-39-1	Approved	Transporter
DB13179	Troleandomycin	Small Molecule	2751-09-9	Approved	Transporter
DB13874	Enasidenib	Small Molecule	1446502-11-9	Approved\|Investigational	Transporter
DB13878	Pibrentasvir	Small Molecule	1353900-92-1	Approved\|Investigational	Transporter
DB13879	Glecaprevir	Small Molecule	1365970-03-1	Approved\|Investigational	Transporter
DB13919	Candesartan	Small Molecule	139481-59-7	Experimental	Transporter
DB13943	Testosterone cypionate	Small Molecule	58-20-8	Approved	Transporter
DB13944	Testosterone enanthate	Small Molecule	315-37-7	Approved	Transporter
DB13946	Testosterone undecanoate	Small Molecule	5949-44-0	Approved\|Investigational	Transporter
DB13951	Stanolone acetate	Small Molecule	1164-91-6	Experimental	Transporter
DB13952	Estradiol acetate	Small Molecule	4245-41-4	Approved\|Investigational	Transporter
DB13953	Estradiol benzoate	Small Molecule	50-50-0	Approved\|Investigational	Transporter
DB13954	Estradiol cypionate	Small Molecule	313-06-4	Approved\|Investigational	Transporter
DB13955	Estradiol dienanthate	Small Molecule	7732-97-0	Approved\|Investigational	Transporter
DB13956	Estradiol valerate	Small Molecule	979-32-8	Approved\|Investigational	Transporter
DB00171	ATP	Small Molecule	56-65-5	Investigational\|Nutraceutical	Target
DB00778	Roxithromycin	Small Molecule	80214-83-1	Approved\|Investigational\|Withdrawn	Target
DB04877	Voacamine	Small Molecule	3371-85-5	Approved\|Investigational	Target
DB04881	Elacridar	Small Molecule	143664-11-3	Investigational	Target
DB04905	Tesmilifene	Small Molecule	98774-23-3	Investigational	Target
DB05449	FM-VP4	Small Molecule	-	Investigational	Target
DB06191	Zosuquidar	Small Molecule	167354-41-8	Investigational	Target
DB06240	Tariquidar	Small Molecule	206873-63-4	Investigational	Target
DB09031	Miltefosine	Small Molecule	58066-85-6	Approved\|Investigational	Target
DB05239	Cobimetinib	Small Molecule	934660-93-2	Approved\|Investigational	Enzyme
DB06670	Odanacatib	Small Molecule	603139-19-1	Investigational	Carrier
DB08930	Dolutegravir	Small Molecule	1051375-16-6	Approved	Carrier
DB09160	Technetium Tc-99m tetrofosmin	Small Molecule	127455-27-0	Approved	Carrier
DB11363	Alectinib	Small Molecule	-	Approved\|Investigational	Carrier

ID	Drug Name	Action	PubMed
C039775	10,11-dihydro-10-hydroxycarbamazepine	"ABCB1 protein results in increased transport of 10,11-dihydro-10-hydroxycarbamazepine"	16190932
C569670	1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one	"ABCB1 protein results in increased transport of 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one"	22696419
C059164	15-hydroxy-5,8,11,13,17-eicosapentaenoic acid	"15-hydroxy-5,8,11,13,17-eicosapentaenoic acid affects the expression of ABCB1 mRNA"	26984781
C119129	18alpha-glycyrrhetinic acid	18alpha-glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
C097775	1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine	"1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine results in decreased activity of ABCB1 protein"	21229979
C505382	1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl)-piperazine	"1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl)-piperazine results in decreased expression of ABCB1 protein"	16891467
C105351	1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene	"[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of ABCB1 protein"	23284745
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	"ABCB1 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"	20522663
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	"Elacridar inhibits the reaction [ABCB1 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]"	20522663
C574037	2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one	"[2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein"	28987325
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ABCB1 mRNA"	25542188
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ABCB1 protein"	25542188
C054917	2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid	"2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid results in increased expression of ABCB1 mRNA"	25542188
C101670	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
C101670	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 mRNA	23466342
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 protein	23466342
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 protein	27888070
C562251	24-norcholan-2,3,24-tryl-2,3,23-sulfuric acid	"24-norcholan-2,3,24-tryl-2,3,23-sulfuric acid results in increased expression of ABCB1 mRNA"	21141967
C521104	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	19223659
C016392	3,3'-diindolylmethane	"[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA"	25542144
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in increased expression of ABCB1 mRNA"	25542144
C016392	3,3'-diindolylmethane	"Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]"	25542144
C061213	3',4',7-trihydroxyisoflavone	"3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]"	22914566
C061213	3',4',7-trihydroxyisoflavone	"3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA"	22914566
C061213	3',4',7-trihydroxyisoflavone	"Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]"	22914566
C061213	3',4',7-trihydroxyisoflavone	"Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]"	22914566
C061213	3',4',7-trihydroxyisoflavone	"CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]"	22914566
C051800	3,4-methylenedioxyethamphetamine	"3,4-methylenedioxyethamphetamine results in decreased activity of ABCB1 protein"	14690877
C434003	3-(4-methylphenylsulfonyl)-2-propenenitrile	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 mRNA]	19647009
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 mRNA]	19647009
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCB1 protein"	23856525
C017906	3-dinitrobenzene	3-dinitrobenzene results in decreased expression of ABCB1 mRNA	16142770
C041477	3-hydroxyflavone	3-hydroxyflavone results in increased expression of ABCB1 mRNA	26238175
C047368	3-methylquercetin	3-methylquercetin results in increased expression of ABCB1 mRNA	26238175
C047368	3-methylquercetin	ABCB1 protein results in increased transport of 3-methylquercetin	15969930
C516284	4-cumylphenol	4-cumylphenol results in increased expression of ABCB1 mRNA	22214767
C015952	4-iodo-2,5-dimethoxyphenylisopropylamine	"4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of ABCB1 protein"	23273999
C000603500	4'-methoxy-1-naphthylfenoterol	4'-methoxy-1-naphthylfenoterol results in decreased expression of ABCB1 protein	27423937
C100230	4-methoxyamphetamine	4-methoxyamphetamine results in decreased activity of ABCB1 protein	14690877
C498826	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	ABCB1 protein affects the susceptibility to 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	28623111
C094782	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone	"5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]"	20438634\|2043863
C094782	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone	"[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]"	20438634
C080669	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one	"5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mRNA"	23470866
C080669	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one	"5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of and results in decreased activity of ABCB1 protein"	23470866
C080669	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one	"diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mRNA]"	23470866
C058722	5-hydroxy-6,8,11,14,17-eicosapentaenoic acid	"5-hydroxy-6,8,11,14,17-eicosapentaenoic acid affects the expression of ABCB1 mRNA"	26984781
C022909	5-methoxypsoralen	5-methoxypsoralen results in decreased activity of ABCB1 protein	29079042
C022909	5-methoxypsoralen	[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
C022909	5-methoxypsoralen	5-methoxypsoralen results in increased expression of ABCB1 mRNA	29079042
C022909	5-methoxypsoralen	Verapamil inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCB1 protein]	29079042
C022909	5-methoxypsoralen	Verapamil inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mRNA]"	23466342
C483321	6-bromoindirubin-3'-oxime	6-bromoindirubin-3'-oxime results in increased expression of ABCB1 mRNA	18624906
C483321	6-bromoindirubin-3'-oxime	6-bromoindirubin-3'-oxime results in increased expression of and results in increased activity of ABCB1 protein	18624906
C010643	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]"	15327746
C095088	6-(N-(7-nitro-2,1,3-benzoxadiazol-4-yl)amino)hexanoyl-glucosylceramide	"ABCB1 protein results in increased transport of 6-(N-(7-nitro-2,1,3-benzoxadiazol-4-yl)amino)hexanoyl-glucosylceramide"	21436125
C580599	6-OH-BDE-47	6-OH-BDE-47 inhibits the reaction [ABCB1 protein results in increased export of Paclitaxel]	28031414
C580599	6-OH-BDE-47	6-OH-BDE-47 results in decreased activity of ABCB1 protein	28031414
C482678	7-hydroxymitragynine	7-hydroxymitragynine results in decreased activity of ABCB1 protein	24841968
C017040	8-azidoadenosine 5'-triphosphate	8-azidoadenosine 5'-triphosphate binds to ABCB1 protein	14978246
C017040	8-azidoadenosine 5'-triphosphate	ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate	11027628
C017040	8-azidoadenosine 5'-triphosphate	beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
C017040	8-azidoadenosine 5'-triphosphate	Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]	14978246
C017040	8-azidoadenosine 5'-triphosphate	fluoroaluminum promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
C017040	8-azidoadenosine 5'-triphosphate	Verapamil promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
C063380	9-((2-phosphonylmethoxy)ethyl)guanine	9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
C048324	abamectin	abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C048324	abamectin	abamectin results in decreased activity of ABCB1 protein	25865432
C023710	abietic acid	abietic acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D000070	Acebutolol	Acebutolol binds to ABCB1 protein	10783826
D000074	Acenocoumarol	ABCB1 gene polymorphism affects the susceptibility to Acenocoumarol	18021343
D000082	Acetaminophen	ABCB1 protein affects the susceptibility to Acetaminophen	16930294
D000082	Acetaminophen	ABCB1 protein results in increased transport of Acetaminophen	16930294
D000082	Acetaminophen	Acetaminophen promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808
D000082	Acetaminophen	Acetaminophen results in increased activity of ABCB1 protein	16930294\|1752680
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 mRNA	26690555
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 protein	16930294\|1762797
D000082	Acetaminophen	Verapamil inhibits the reaction [Acetaminophen results in increased activity of ABCB1 protein]	16930294\|1752680
D000082	Acetaminophen	Acetaminophen promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	15276087
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 mRNA	17522070
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 protein	15276087
C043377	acetochlor	ABCB1 protein affects the reaction [acetochlor results in increased susceptibility to Paclitaxel]	18433974
C043377	acetochlor	acetochlor results in increased activity of ABCB1 protein	18433974
C056165	acetovanillone	acetovanillone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C056165	acetovanillone	acetovanillone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D000111	Acetylcysteine	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]	25824409
D000111	Acetylcysteine	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]	25824409
D000111	Acetylcysteine	"Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]"	22914566
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]	23867903
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D000157	Aconitine	ABCB1 affects the transport of Aconitine	23562926
D000157	Aconitine	ABCB1 results in decreased susceptibility to Aconitine	23562926
D000255	Adenosine Triphosphate	ABCB1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate	14978246
D000255	Adenosine Triphosphate	ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate	18829547\|1895504
D000255	Adenosine Triphosphate	aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
D000255	Adenosine Triphosphate	[Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D000255	Adenosine Triphosphate	crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	22233293
D000255	Adenosine Triphosphate	Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	14978246
D000255	Adenosine Triphosphate	lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18829547
D000255	Adenosine Triphosphate	[Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D000255	Adenosine Triphosphate	[Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D000255	Adenosine Triphosphate	nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased methylation of ABCB1 gene	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of ABCB1 mRNA	27153756
C000188	alachlor	ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]	18433974
C000188	alachlor	alachlor results in increased activity of ABCB1 protein	18433974
D000450	Aldosterone	ABCB1 protein results in increased secretion of Aldosterone	22464980
D000450	Aldosterone	Aldosterone results in increased expression of ABCB1 mRNA	12387747
D000450	Aldosterone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
D000450	Aldosterone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
C446481	aliskiren	ABCB1 protein affects the susceptibility to aliskiren	24388840
C006452	allicin	allicin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C038491	allyl sulfide	allyl sulfide results in increased expression of ABCB1 mRNA	22397993
D000517	alpha-Chlorohydrin	alpha-Chlorohydrin results in decreased expression of ABCB1 protein	17803981
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
D000602	Amino Acids, Peptides, and Proteins	"Amino Acids, Peptides, and Proteins inhibits the reaction [Carbamazepine results in increased expression of ABCB1 protein]"	18473823
D000602	Amino Acids, Peptides, and Proteins	"Amino Acids, Peptides, and Proteins inhibits the reaction [etiracetam results in increased expression of ABCB1 protein]"	18473823
D000602	Amino Acids, Peptides, and Proteins	"Amino Acids, Peptides, and Proteins inhibits the reaction [Phenobarbital results in increased expression of ABCB1 protein]"	18473823
D000602	Amino Acids, Peptides, and Proteins	"Amino Acids, Peptides, and Proteins inhibits the reaction [Phenytoin results in increased expression of ABCB1 protein]"	18473823
D000602	Amino Acids, Peptides, and Proteins	"Amino Acids, Peptides, and Proteins inhibits the reaction [tiagabine results in increased expression of ABCB1 protein]"	18473823
D000602	Amino Acids, Peptides, and Proteins	"Amino Acids, Peptides, and Proteins inhibits the reaction [topiramate results in increased expression of ABCB1 protein]"	18473823
D000638	Amiodarone	Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D000638	Amiodarone	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D000638	Amiodarone	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D000638	Amiodarone	Amiodarone results in decreased activity of ABCB1 protein	11231118
D000638	Amiodarone	Amiodarone affects the expression of ABCB1 mRNA	18355885
D000639	Amitriptyline	Amitriptyline affects the expression of ABCB1 mRNA	18355885
C049148	amorphigenin	amorphigenin affects the activity of ABCB1 protein	15796199
C095108	amprenavir	ABCB1 protein results in increased transport of amprenavir	23976943
C095108	amprenavir	amprenavir binds to ABCB1 protein	23976943
C095108	amprenavir	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of amprenavir	23976943
C098751	AN 204	AN 204 results in increased expression of ABCB1 mRNA	16047355\|1605147
C416531	AN 215	AN 215 results in increased expression of ABCB1 mRNA	16051478
C110845	AN 238	AN 238 results in increased expression of ABCB1 mRNA	16047355
C010680	antibiotic G 418	ABCB1 protein results in increased transport of antibiotic G 418	20018165
C010680	antibiotic G 418	antibiotic G 418 results in decreased expression of ABCB1 mRNA	20018165
D000927	Anticonvulsants	ABCB1 protein affects the susceptibility to Anticonvulsants	18408562
D000927	Anticonvulsants	ABCB1 protein results in decreased susceptibility to Anticonvulsants	15581025
C473343	antofine	antofine results in decreased expression of ABCB1 mRNA	22120505
C473343	antofine	antofine results in decreased expression of ABCB1 protein	22120505
C102351	apicidin	ABCB1 protein results in decreased susceptibility to apicidin	16049968
D001151	Arsenic	ABCB1 protein results in increased export of Arsenic	12387749
C006632	arsenic trioxide	arsenic trioxide results in decreased expression of ABCB1 mRNA	15979894\|2221448
C006632	arsenic trioxide	arsenic trioxide results in decreased expression of ABCB1 protein	14642128\|1563452
C006632	arsenic trioxide	arsenic trioxide results in increased expression of ABCB1 mRNA	21945491
C006632	arsenic trioxide	arsenic trioxide results in increased activity of ABCB1 protein	22580103
C006632	arsenic trioxide	arsenic trioxide results in increased expression of ABCB1 mRNA	22580103
C031327	artemisinine	artemisinine results in decreased activity of ABCB1 protein	15761118
C031327	artemisinine	artemisinine results in increased expression of ABCB1 mRNA	15761118
C078098	ar-turmerone	ar-turmerone results in increased expression of ABCB1 mRNA	22181075
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of ABCB1 protein"	18385176
D017638	Asbestos, Crocidolite	"ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased expression of ABCB1 protein]"	18385176
D001205	Ascorbic Acid	"Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]"	22914566
C022870	asoxime chloride	[tariquidar results in decreased activity of ABCB1 protein] which results in increased abundance of asoxime chloride	21600273
D001241	Aspirin	Aspirin results in increased activity of ABCB1 protein	19840843
D001241	Aspirin	Aspirin results in increased expression of ABCB1 mRNA	21900887
D001241	Aspirin	Aspirin results in increased expression of ABCB1 protein	21900887
D001241	Aspirin	Aspirin results in increased expression of ABCB1 mRNA	21900887
D001241	Aspirin	Aspirin results in increased expression of ABCB1 protein	21900887
D001241	Aspirin	[Aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of clopidogrel	21900887
D000069059	Atorvastatin Calcium	ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin Calcium]	19802823
D000069059	Atorvastatin Calcium	ABCB1 protein results in increased transport of Atorvastatin Calcium	10751037\|1561615
D000069059	Atorvastatin Calcium	ABCB1 protein results in increased transport of Atorvastatin Calcium analog	15616150
D000069059	Atorvastatin Calcium	Atorvastatin Calcium analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
D000069059	Atorvastatin Calcium	Atorvastatin Calcium analog results in decreased activity of ABCB1 protein	15616150
D000069059	Atorvastatin Calcium	ABCB1 results in increased transport of Atorvastatin Calcium	19802823
C105832	aurapten	aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
C105832	aurapten	aurapten promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
C019264	avermectin	[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein	23523950
C019264	avermectin	avermectin results in increased expression of and results in increased activity of ABCB1 protein	23523950
C019264	avermectin	[Cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of Calcium]	23523950
C019264	avermectin	Niflumic Acid inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
C019264	avermectin	pyrrolidine dithiocarbamic acid inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
C019264	avermectin	Trifluoperazine inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
C019264	avermectin	Verapamil inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
C100095	azacyclonol	ABCB1 protein affects the transport of azacyclonol	10350002
D001379	Azathioprine	ABCB1 gene polymorphism affects the susceptibility to Azathioprine	17262810
C020976	azelastine	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
C020976	azelastine	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
C020976	azelastine	azelastine results in decreased activity of ABCB1 protein	11231118
C041130	azidopine	azidopine binds to ABCB1 protein	14978246
C041130	azidopine	Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]	14978246
C041552	azidoprazosin	azidoprazosin binds to ABCB1 protein	14978246\|1882954
C041552	azidoprazosin	Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]	14978246
C041552	azidoprazosin	lapatinib inhibits the reaction [azidoprazosin binds to ABCB1 protein]	18829547
C041552	azidoprazosin	[Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]	1381629
C006680	baicalein	baicalein results in increased expression of ABCB1 mRNA	25625231
C004456	beauvericin	beauvericin results in decreased activity of ABCB1 protein	27474255
C004456	beauvericin	beauvericin results in increased expression of ABCB1 mRNA	27474255
D001507	Beclomethasone	ABCB1 protein results in increased secretion of Beclomethasone	22464980
D001507	Beclomethasone	Beclomethasone inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D001507	Beclomethasone	Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
D001507	Beclomethasone	Beclomethasone results in increased expression of ABCB1 mRNA	15370884
D001507	Beclomethasone	Beclomethasone results in increased expression of ABCB1 protein	22464980
D001507	Beclomethasone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
D001507	Beclomethasone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
C061004	benidipine	benidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D001554	Benzene	ABCB1 affects the susceptibility to Benzene	21619790
D001554	Benzene	Benzene results in increased expression of ABCB1 mRNA	19162166
C026487	benzo(e)pyrene	benzo(e)pyrene results in increased expression of ABCB1 mRNA	17408918
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of ABCB1 mRNA	15566942
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ABCB1 mRNA	15566942\|1654541
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ABCB1 mRNA	11096091
C047307	benzoylaconine	ABCB1 protein results in increased transport of benzoylaconine	23200901
C047307	benzoylaconine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
C047307	benzoylaconine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
C479202	benzoylhypaconine	ABCB1 protein results in increased transport of benzoylhypaconine	23200901
C479202	benzoylhypaconine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
C479202	benzoylhypaconine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
C085283	benzoylmesaconine	ABCB1 protein results in increased transport of benzoylmesaconine	23200901
C085283	benzoylmesaconine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
C085283	benzoylmesaconine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
D015764	Bepridil	Bepridil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C068337	bergamottin	bergamottin results in increased expression of ABCB1 mRNA	19148864
C068337	bergamottin	bergamottin results in increased expression of ABCB1 protein	19148864
C035982	beryllium fluoride	beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
D004958	Estradiol	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 mRNA]	19813763
D004958	Estradiol	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 protein]	19813763
D004958	Estradiol	EGF protein promotes the reaction [Estradiol results in decreased expression of ABCB1 mRNA]	24758408
D004958	Estradiol	ESR1 protein affects the reaction [Estradiol results in decreased expression of ABCB1 protein]	16925584
D004958	Estradiol	Estradiol results in decreased expression of ABCB1 mRNA	24758408
D004958	Estradiol	[Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine	16925584
D004958	Estradiol	Estradiol results in increased expression of ABCB1 mRNA	15290871\|1981376
D004958	Estradiol	Estradiol results in increased expression of ABCB1 protein	19580841\|1981376
D004958	Estradiol	Tamoxifen inhibits the reaction [Estradiol results in decreased expression of ABCB1 protein]	16925584
D004958	Estradiol	Estradiol results in increased expression of ABCB1 mRNA	27569056
C010789	beta-pinene	beta-pinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D001629	Bezafibrate	Bezafibrate results in decreased expression of ABCB1 mRNA	21872554
D001629	Bezafibrate	Bezafibrate results in increased expression of ABCB1 mRNA	21872554
C017807	bisbenzimide ethoxide trihydrochloride	abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C017807	bisbenzimide ethoxide trihydrochloride	ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride	25865432
C017807	bisbenzimide ethoxide trihydrochloride	emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C017807	bisbenzimide ethoxide trihydrochloride	Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C017807	bisbenzimide ethoxide trihydrochloride	9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
D017298	Bisoprolol	ABCB1 protein results in increased transport of Bisoprolol	16671962
D017298	Bisoprolol	Bisoprolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D017298	Bisoprolol	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Bisoprolol]	16671962
C006780	bisphenol A	bisphenol A affects the expression of ABCB1 mRNA	24793377
C006780	bisphenol A	bisphenol A results in increased expression of ABCB1 mRNA	22214767
C006780	bisphenol A	bisphenol A results in increased expression of ABCB1 mRNA	27569056
C006780	bisphenol A	bisphenol A results in increased expression of ABCB1 mRNA	25127357
C006780	bisphenol A	bisphenol A results in decreased expression of ABCB1 mRNA	25181051
C492482	bisphenol B	bisphenol B results in increased expression of ABCB1 mRNA	22214767
C504983	BMS 536924	BMS 536924 results in decreased expression of ABCB1 protein	26394120
D000069286	Bortezomib	ATP2A1 protein affects the reaction [Bortezomib results in decreased expression of ABCB1]	25576094
D000069286	Bortezomib	Bortezomib results in decreased activity of ABCB1 protein	25576094
D000069286	Bortezomib	Bortezomib results in decreased expression of ABCB1	25576094
C086232	bosentan	bosentan results in decreased expression of ABCB1 mRNA	28369585
D001971	Bromocriptine	Bromocriptine results in increased expression of ABCB1 protein	9111066
D001971	Bromocriptine	Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
D001971	Bromocriptine	Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
C514835	bromotetrandrine	bromotetrandrine results in decreased expression of ABCB1 protein	15378274
C514835	bromotetrandrine	[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of ABCB1 mRNA	22114476
C514835	bromotetrandrine	[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of ABCB1 mRNA	22114476
D019819	Budesonide	Budesonide results in increased expression of ABCB1 protein	22464980
C022777	bufalin	bufalin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C018475	butyraldehyde	butyraldehyde results in increased expression of ABCB1 mRNA	26079696
D002087	Butyrates	Butyrates results in increased expression of ABCB1 mRNA	15711177
D020148	Butyric Acid	Butyric Acid results in increased expression of ABCB1 mRNA	15711177
D002104	Cadmium	Cadmium results in increased expression of ABCB1 protein	15084411
D002104	Cadmium	ABCB1 protein inhibits the reaction [Cadmium results in increased abundance of Ceramides]	21436125
D002104	Cadmium	ABCB1 protein results in decreased susceptibility to Cadmium	21436125
D002104	Cadmium	Cadmium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D002104	Cadmium	ABCB1 protein results in decreased susceptibility to Cadmium	21436125
D002104	Cadmium	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Cadmium]	21436125
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	1967174
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	23741332
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	25956639
D019256	Cadmium Chloride	Cadmium Chloride results in increased transport of ABCB1 protein	25956639
D019256	Cadmium Chloride	titanium dioxide inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1 mRNA]	25956639
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	18804290
D019256	Cadmium Chloride	Cadmium Chloride results in increased activity of ABCB1 protein	22580103
D019256	Cadmium Chloride	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D019256	Cadmium Chloride	ABCB1 results in decreased susceptibility to Cadmium Chloride	10636889
D019256	Cadmium Chloride	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D019256	Cadmium Chloride	Cadmium Chloride promotes the reaction [TCF4 protein binds to ABCB1 promoter]	20459685
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1	10636889
D019256	Cadmium Chloride	Cyclosporine inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D019256	Cadmium Chloride	pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D019256	Cadmium Chloride	valspodar inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D019256	Cadmium Chloride	Verapamil inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
C085925	calcein AM	ABCB1 protein results in increased transport of calcein AM	26929997
C085925	calcein AM	[musk ketone results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	[Pentachlorophenol results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	[reversin 205 results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	19223659
C085925	calcein AM	ABCB1 protein affects the export of calcein AM	10617675
C085925	calcein AM	ABCB1 protein results in increased export of calcein AM	29174985
C085925	calcein AM	ABCB1 protein results in increased secretion of calcein AM	16121039
C085925	calcein AM	ABCB1 protein results in increased transport of calcein AM	15616150\|1922365
C085925	calcein AM	Atorvastatin Calcium analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
C085925	calcein AM	calcein AM results in increased activity of ABCB1 protein mutant form	12711602
C085925	calcein AM	chlorpyrifos-methyl affects the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
C085925	calcein AM	deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]	29174985
C085925	calcein AM	Diazinon inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	[Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	fenvalerate inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Lovastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
C085925	calcein AM	[phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
C085925	calcein AM	Simvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
C085925	calcein AM	sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]	16121039
C085925	calcein AM	valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
C085925	calcein AM	[Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]	16121039
C085925	calcein AM	Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
C085925	calcein AM	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	ABCB1 protein results in increased export of calcein AM analog	25542188
D002118	Calcium	[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein	23523950
D002118	Calcium	[Cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of Calcium]	23523950
D002118	Calcium	Niflumic Acid inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D002118	Calcium	Verapamil inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D002118	Calcium	Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]	25862123
D002118	Calcium	Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D002166	Camptothecin	Camptothecin results in decreased expression of ABCB1 protein	10692111
C100098	cannogenin thevetoside	cannogenin thevetoside inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D002211	Capsaicin	Capsaicin affects the reaction [ABCB1 protein results in increased export of Digoxin]	16674925
D002211	Capsaicin	Capsaicin results in increased expression of ABCB1 mRNA	16674925
D002211	Capsaicin	Capsaicin results in increased expression of ABCB1 protein	16674925
D002220	Carbamazepine	Carbamazepine results in decreased expression of ABCB1 mRNA	21872554
D002220	Carbamazepine	ABCB1 gene polymorphism affects the susceptibility to Carbamazepine	16753003
D002220	Carbamazepine	ABCB1 protein affects the susceptibility to Carbamazepine	14749549\|1737612
D002220	Carbamazepine	ABCB1 protein affects the transport of Carbamazepine	17376120
D002220	Carbamazepine	Carbamazepine results in decreased activity of ABCB1 protein	18408562
D002220	Carbamazepine	Carbamazepine results in increased expression of ABCB1 mRNA	15371980\|1684240
D002220	Carbamazepine	Carbamazepine results in increased expression of ABCB1 protein	16842400
D002220	Carbamazepine	Carbamazepine results in decreased expression of ABCB1 mRNA	19632730
D002220	Carbamazepine	"Amino Acids, Peptides, and Proteins inhibits the reaction [Carbamazepine results in increased expression of ABCB1 protein]"	18473823
D002220	Carbamazepine	Carbamazepine results in increased expression of ABCB1 protein	15569486\|1847382
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of ABCB1 mRNA	15120965
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of ABCB1 mRNA	17522070
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of ABCB1 protein	12642476
D002298	Cardenolides	Cardenolides inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D002330	Carmustine	Carmustine results in increased expression of ABCB1 protein	15239124
D002330	Carmustine	[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine	11792417
D002330	Carmustine	[MGMT protein mutant form co-treated with ABCB1 protein] results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]	16733832
C043211	carvedilol	ABCB1 protein results in increased transport of carvedilol	16671962
C043211	carvedilol	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
C043211	carvedilol	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]] which results in decreased susceptibility to Daunorubicin	12708479
C043211	carvedilol	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100\|1667196
C043211	carvedilol	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
C043211	carvedilol	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]] which results in decreased susceptibility to Doxorubicin	12708479
C043211	carvedilol	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
C043211	carvedilol	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]] which results in decreased susceptibility to Paclitaxel	12708479
C043211	carvedilol	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
C043211	carvedilol	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine	12708479
C043211	carvedilol	carvedilol results in decreased activity of ABCB1 protein	10571255
C043211	carvedilol	[carvedilol results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
C043211	carvedilol	[carvedilol results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
C043211	carvedilol	valspodar inhibits the reaction [ABCB1 protein results in increased transport of carvedilol]	16671962
C043211	carvedilol	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased uptake of carvedilol	17609666
C043211	carvedilol	carvedilol binds to ABCB1 protein	10783826
C043211	carvedilol	carvedilol metabolite binds to ABCB1 protein	10783826
D000068579	Celecoxib	Celecoxib results in decreased expression of ABCB1 protein	21745461
D000068579	Celecoxib	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide	19562670
D000068579	Celecoxib	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Tamoxifen	19562670
D000068579	Celecoxib	Celecoxib results in increased expression of ABCB1 mRNA	21745461
D000068579	Celecoxib	Celecoxib results in increased methylation of ABCB1 promoter	19562670
D000068579	Celecoxib	ABCB1 results in increased susceptibility to Celecoxib	17510421
D000068579	Celecoxib	Celecoxib results in decreased expression of ABCB1	17510421
D002491	Central Nervous System Agents	Central Nervous System Agents results in increased activity of ABCB1 protein	23273999
C006947	cepharanthine	cepharanthine results in decreased activity of ABCB1 protein	15958061
D002518	Ceramides	ABCB1 protein inhibits the reaction [Cadmium results in increased abundance of Ceramides]	21436125
C086276	cerivastatin	ABCB1 protein affects the export of cerivastatin	15901800
D017332	Cetirizine	ABCB1 protein results in increased export of Cetirizine	12584158
D002699	Chlorambucil	Chlorambucil results in increased expression of ABCB1 protein	15239124
C084597	chlorcyclizine	ABCB1 protein affects the transport of chlorcyclizine	15666293
D002706	Chlordan	Chlordan results in increased expression of ABCB1 mRNA	24464585
D007631	Chlordecone	Chlordecone results in decreased activity of ABCB1 protein	24464585
D002725	Chloroform	Chloroform results in increased expression of ABCB1 mRNA	15120965
D002725	Chloroform	Chloroform results in increased expression of ABCB1 mRNA	17522070
D002738	Chloroquine	Chloroquine results in decreased expression of ABCB1 mRNA	27692344
D002738	Chloroquine	Chloroquine results in decreased expression of ABCB1 protein	27692344
D002744	Chlorpheniramine	ABCB1 protein affects the transport of Chlorpheniramine	15666293
D002746	Chlorpromazine	Chlorpromazine analog results in increased expression of ABCB1 mRNA	15924885
D002746	Chlorpromazine	Chlorpromazine results in decreased activity of ABCB1 protein	16810505
D004390	Chlorpyrifos	Chlorpyrifos binds to ABCB1 protein	8917702
D004390	Chlorpyrifos	Chlorpyrifos inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of ABCB1 mRNA	28549829
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of ABCB1 protein	28549829
C007031	chlorpyrifos-methyl	chlorpyrifos-methyl affects the activity of ABCB1 protein	21783720
C007031	chlorpyrifos-methyl	chlorpyrifos-methyl affects the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C561233	cholan-2,3,24-tryl-2,3,24-trisulfate	"cholan-2,3,24-tryl-2,3,24-trisulfate results in increased expression of ABCB1 mRNA"	21141967
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 mRNA	24384915
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 protein	24384915
C031180	chrysene	chrysene results in increased expression of ABCB1 mRNA	15566942
C043561	chrysin	chrysin affects the activity of ABCB1 protein	15796199
C043561	chrysin	chrysin results in decreased activity of ABCB1 protein	20457140
C043561	chrysin	[chrysin results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
C043561	chrysin	chrysin results in increased expression of ABCB1 protein	20457140
C472594	chrysophsin	[Epirubicin analog co-treated with chrysophsin analog] results in increased expression of ABCB1 mRNA	26335193
C472594	chrysophsin	[Epirubicin co-treated with chrysophsin] results in increased expression of ABCB1 mRNA	26335193
C120481	ciclesonide	ciclesonide results in increased expression of ABCB1 protein	22464980
D015377	Cilastatin	Cilastatin inhibits the reaction [Vancomycin results in decreased expression of and affects the localization of ABCB1 protein]	28549670
D015377	Cilastatin	Cilastatin results in increased expression of and affects the localization of ABCB1 protein	28549670
C010086	cinchonine	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	20196146
C010086	cinchonine	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
C010086	cinchonine	cinchonine analog results in decreased expression of ABCB1 protein	20196146
C010086	cinchonine	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	20196146
C010086	cinchonine	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
C010086	cinchonine	cinchonine results in decreased expression of ABCB1 protein	20196146
C108217	citronellal	citronellal inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
C108217	citronellal	citronellal results in decreased activity of ABCB1 protein	15890377
C108217	citronellal	[citronellal results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
C007078	citronellol	citronellol inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
C007078	citronellol	citronellol results in decreased activity of ABCB1 protein	15890377
C007078	citronellol	[citronellol results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
C504653	CJX1, amlodipine derivative	"CJX1, amlodipine derivative inhibits the reaction [ABCB1 protein results in decreased secretion of Doxorubicin]"	15967469
C504653	CJX1, amlodipine derivative	"CJX1, amlodipine derivative results in decreased activity of ABCB1 protein"	15967469
C523261	CJY compound	CJY compound results in decreased activity of ABCB1 protein	17637197
D002994	Clofibrate	Clofibrate results in decreased expression of ABCB1 mRNA	19224547
D002995	Clofibric Acid	Clofibric Acid results in increased expression of ABCB1 mRNA	22559005
D002997	Clomipramine	Clomipramine affects the expression of ABCB1 mRNA	18355885
C055162	clopidogrel	ABCB1 gene affects the reaction [CYP2C19 gene affects the susceptibility to clopidogrel]	19934793
C055162	clopidogrel	ABCB1 gene affects the susceptibility to clopidogrel	17112805
C055162	clopidogrel	ABCB1 gene polymorphism affects the susceptibility to clopidogrel	20180610
C055162	clopidogrel	ABCB1 gene SNP affects the susceptibility to clopidogrel	19106083
C055162	clopidogrel	ABCB1 protein results in decreased uptake of clopidogrel	17112805
C055162	clopidogrel	ABCB1 protein results in increased secretion of clopidogrel	17112805
C055162	clopidogrel	clopidogrel results in decreased activity of ABCB1 protein	17112805
C055162	clopidogrel	clopidogrel results in decreased expression of ABCB1 mRNA	17112805
C055162	clopidogrel	clopidogrel results in decreased expression of ABCB1 protein	17112805
C055162	clopidogrel	[Aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of clopidogrel	21900887
D003022	Clotrimazole	Clotrimazole results in decreased expression of ABCB1 mRNA	22559005
D003022	Clotrimazole	Clotrimazole binds to ABCB1 protein	8917702
D003022	Clotrimazole	Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D003022	Clotrimazole	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D003022	Clotrimazole	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D003022	Clotrimazole	Clotrimazole results in increased expression of ABCB1 protein	8632764
D003024	Clozapine	Clozapine results in decreased activity of ABCB1 protein	16810505
D003024	Clozapine	Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
D003024	Clozapine	Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
D003024	Clozapine	Clozapine inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
C502467	cnidiadin	cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]	15824923
C502467	cnidiadin	cnidiadin results in decreased activity of ABCB1 protein	15824923
C502467	cnidiadin	[cnidiadin results in decreased activity of ABCB1 protein] which results in increased susceptibility to Vinca Alkaloids	15824923
D003035	Cobalt	Cobalt results in increased activity of ABCB1 protein	2900677
D003035	Cobalt	[Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
C018021	cobaltous chloride	cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of ABCB1 mRNA]	19128456
C018021	cobaltous chloride	HIPK2 protein inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of ABCB1 mRNA]]	19128456
C018021	cobaltous chloride	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]	19714248
D003078	Colchicine	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of Colchicine]	15466210
D003078	Colchicine	ABCB1 protein affects the transport of Colchicine	16007523
D003078	Colchicine	ABCB1 protein results in decreased susceptibility to Colchicine	15112361\|1572547
D003078	Colchicine	ABCB1 protein results in increased export of Colchicine	15112361
D003078	Colchicine	Colchicine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D003078	Colchicine	Colchicine results in increased expression of ABCB1	24759273
D003078	Colchicine	Colchicine results in increased expression of ABCB1 mRNA	15342794
D003078	Colchicine	[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Colchicine	11792417
D003078	Colchicine	ABCB1 results in decreased susceptibility to Colchicine	20557448
D005576	Colforsin	Colforsin results in increased expression of ABCB1 mRNA	23164983
D005576	Colforsin	[Rifampin co-treated with Colforsin] results in increased expression of ABCB1 protein	23164983
D005576	Colforsin	Colforsin results in increased expression of ABCB1 mRNA	12926078
D005576	Colforsin	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA]	12926078
D003300	Copper	Copper results in increased expression of ABCB1 protein	15084411
D003300	Copper	Copper inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D003300	Copper	Copper results in increased expression of ABCB1 mRNA	19501419
C021984	corexit 9527	corexit 9527 results in increased expression of ABCB1 mRNA	19501419
C551994	crizotinib	crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	22233293
C551994	crizotinib	crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293
C551994	crizotinib	crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	22233293
C551994	crizotinib	crizotinib results in decreased activity of ABCB1 protein	28369651
C038106	cucurbitacin I	cucurbitacin I inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D003474	Curcumin	ABCB1 affects the susceptibility to Curcumin	15476675
D003474	Curcumin	ABCB1 protein results in decreased susceptibility to Curcumin	27318188
D003474	Curcumin	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D003474	Curcumin	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D003474	Curcumin	Curcumin analog results in decreased expression of ABCB1 protein	26689174
D003474	Curcumin	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D003474	Curcumin	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D003474	Curcumin	Curcumin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
D003474	Curcumin	Curcumin results in decreased expression of ABCB1 mRNA	17121181\|1841405
D003474	Curcumin	Curcumin results in decreased expression of and results in decreased activity of ABCB1 protein	18439772
D003474	Curcumin	[sulfinosine co-treated with Curcumin] results in decreased expression of ABCB1 mRNA	18414057
D003474	Curcumin	Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]	18200517
D003513	Cycloheximide	Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]	7476894
D003513	Cycloheximide	Cycloheximide results in increased expression of ABCB1 mRNA	7476894
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003513	Cycloheximide	Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003513	Cycloheximide	Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003520	Cyclophosphamide	ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]	12576456
D003520	Cyclophosphamide	ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D003520	Cyclophosphamide	[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D003520	Cyclophosphamide	Cyclophosphamide results in increased expression of ABCB1 protein	20041327
D003520	Cyclophosphamide	NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]	20041327
D003520	Cyclophosphamide	Cyclophosphamide results in decreased expression of ABCB1 mRNA	20623750
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of Calcium]	23523950
D016572	Cyclosporine	ABCB1 protein affects the export of Cyclosporine	15964336
D016572	Cyclosporine	ABCB1 protein affects the susceptibility to Cyclosporine	12387747\|2862311
D016572	Cyclosporine	ABCB1 protein affects the transport of Cyclosporine	15964407
D016572	Cyclosporine	ABCB1 protein polymorphism affects the susceptibility to Cyclosporine	15772250
D016572	Cyclosporine	ABCB1 protein results in increased transport of Cyclosporine	17045309
D016572	Cyclosporine	Cyclosporine affects the expression of ABCB1 mRNA	20106945
D016572	Cyclosporine	Cyclosporine binds to and results in decreased activity of ABCB1 protein	23976943
D016572	Cyclosporine	[Cyclosporine binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D016572	Cyclosporine	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA	17096884
D016572	Cyclosporine	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein	17096884
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497\|7905786
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D016572	Cyclosporine	Cyclosporine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein	12387747\|1631693
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein mutant form	12711602
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D016572	Cyclosporine	Cyclosporine results in decreased expression of ABCB1 mRNA	17096884\|2497309
D016572	Cyclosporine	Cyclosporine results in decreased expression of ABCB1 protein	17096884
D016572	Cyclosporine	Cyclosporine results in increased expression of ABCB1 mRNA	12387747\|2556210
D016572	Cyclosporine	Plant Extracts affects the reaction [ABCB1 protein results in increased transport of Cyclosporine]	12545142
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein	17609666
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased uptake of carvedilol	17609666
D016572	Cyclosporine	[Thioacetamide co-treated with Cyclosporine] results in increased expression of ABCB1 mRNA	15770714
D016572	Cyclosporine	Cyclosporine affects the folding of and affects the localization of ABCB1 protein mutant form	15530432
D016572	Cyclosporine	Cyclosporine affects the localization of ABCB1 protein mutant form	22184139
D016572	Cyclosporine	Cyclosporine affects the metabolism of and affects the folding of ABCB1 protein mutant form	22184139
D016572	Cyclosporine	Cyclosporine binds to ABCB1 protein	7808368
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of retrorsine]	24799337
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein	15744065\|2320090
D016572	Cyclosporine	Cyclosporine results in increased activity of ABCB1 protein mutant form	22184139
D003524	Cyclosporins	Cyclosporins affects the activity of ABCB1 protein	15788683
C017160	cypermethrin	cypermethrin results in increased activity of ABCB1 protein	17490606
C017160	cypermethrin	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of cypermethrin]	17490606
D003561	Cytarabine	ABCB1 protein affects the susceptibility to Cytarabine	17852453
D003561	Cytarabine	Cytarabine results in increased expression of ABCB1	11573427
D003609	Dactinomycin	ABCB1 protein results in decreased susceptibility to Dactinomycin	15725475
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 mRNA]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 protein]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 mRNA]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 protein]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCB1 mRNA]	1967174
D003609	Dactinomycin	ABCB1 protein results in decreased susceptibility to Dactinomycin	11455017
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003609	Dactinomycin	Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003609	Dactinomycin	Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003630	Daunorubicin	[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
D003630	Daunorubicin	ABCB1 affects the susceptibility to Daunorubicin	12174371
D003630	Daunorubicin	ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]	20957165\|2095716
D003630	Daunorubicin	ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]	20957165\|2095716
D003630	Daunorubicin	ABCB1 mutant form promotes the reaction [Magnetite Nanoparticles results in increased susceptibility to Daunorubicin]	20957165
D003630	Daunorubicin	ABCB1 mutant form results in increased susceptibility to Daunorubicin	20957165
D003630	Daunorubicin	ABCB1 protein affects the susceptibility to Daunorubicin	24954033
D003630	Daunorubicin	ABCB1 protein results in decreased uptake of Daunorubicin	10617675
D003630	Daunorubicin	ABCB1 protein results in increased export of Daunorubicin	12526924\|9815696
D003630	Daunorubicin	ABCB1 protein results in increased import of Daunorubicin	18955043
D003630	Daunorubicin	ABCB1 protein results in increased transport of Daunorubicin	11231118\|1270847
D003630	Daunorubicin	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	aurapten promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
D003630	Daunorubicin	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
D003630	Daunorubicin	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]] which results in decreased susceptibility to Daunorubicin	12708479
D003630	Daunorubicin	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D003630	Daunorubicin	[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of ABCB1 mRNA	22114476
D003630	Daunorubicin	[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of ABCB1 mRNA	22114476
D003630	Daunorubicin	Daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]	20957165\|2095716
D003630	Daunorubicin	Daunorubicin promotes the reaction [Magnetite Nanoparticles results in decreased expression of ABCB1 protein]	20957165
D003630	Daunorubicin	Daunorubicin results in decreased expression of ABCB1 mRNA	20957165
D003630	Daunorubicin	Daunorubicin results in decreased expression of ABCB1 protein	20957165
D003630	Daunorubicin	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]]	20957165\|2095716
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]]	20957165\|2095716
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form results in increased susceptibility to Daunorubicin]	20957165
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [Daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]]	20957165\|2095716
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]	20957165
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]	20957165
D003630	Daunorubicin	[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
D003630	Daunorubicin	Mitotane inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
D003630	Daunorubicin	nobiletin promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
D003630	Daunorubicin	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Daunorubicin]	15466210
D003630	Daunorubicin	[Sodium Azide co-treated with Iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D003630	Daunorubicin	valspodar inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
D003630	Daunorubicin	Verapamil inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D003630	Daunorubicin	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
D003630	Daunorubicin	Verapamil inhibits the reaction [[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D003630	Daunorubicin	ABCB1 results in decreased susceptibility to Daunorubicin	20557448
D003630	Daunorubicin	ABCB1 protein affects the transport of Daunorubicin	12642476
D003630	Daunorubicin	Daunorubicin inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
D003630	Daunorubicin	ABCB1 results in decreased susceptibility to Daunorubicin	18310528
D003630	Daunorubicin	Mometasone Furoate inhibits the reaction [ABCB1 results in decreased susceptibility to Daunorubicin]	18310528
D003634	DDT	DDT metabolite results in decreased activity of ABCB1 protein	23169446
D003634	DDT	DDT results in increased expression of ABCB1 mRNA	15710169\|2446458
C014347	decitabine	[decitabine affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531\|1867353
C014347	decitabine	[[decitabine co-treated with trichostatin A] affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531\|1867353
C014347	decitabine	decitabine promotes the reaction [trichostatin A results in increased expression of ABCB1 mRNA]	27570640
C014347	decitabine	decitabine results in increased expression of ABCB1 mRNA	27570640
C478098	dehydroandrographolide	dehydroandrographolide inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D003703	Demecolcine	Demecolcine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D003703	Demecolcine	Demecolcine results in increased activity of ABCB1 protein mutant form	12711602
D003840	Deoxycholic Acid	Deoxycholic Acid metabolite results in increased expression of ABCB1 mRNA	27871908
D003847	Deoxyglucose	Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
C007262	deoxynivalenol	ABCB1 protein results in decreased susceptibility to deoxynivalenol	29174985
C007262	deoxynivalenol	deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]	29174985
C036116	desethylamiodarone	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
C036116	desethylamiodarone	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
C036116	desethylamiodarone	desethylamiodarone results in decreased activity of ABCB1 protein	11231118
C494355	desisobutyrylciclesonide	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
C494355	desisobutyrylciclesonide	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C121345	desloratadine	ABCB1 protein results in increased export of desloratadine	12584158
C054114	desmethylazelastine	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
C054114	desmethylazelastine	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
C054114	desmethylazelastine	desmethylazelastine results in decreased activity of ABCB1 protein	11231118
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of IFNG protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of IL2 protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of IL4 protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of TNF protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the susceptibility to Dexamethasone	16321374
D003907	Dexamethasone	ABCB1 protein results in increased secretion of Dexamethasone	22464980
D003907	Dexamethasone	Dexamethasone results in decreased activity of ABCB1 protein	12387747
D003907	Dexamethasone	Dexamethasone results in increased expression of ABCB1 mRNA	12387747
D003907	Dexamethasone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
D003907	Dexamethasone	[Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone	20080907
D003907	Dexamethasone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
D003907	Dexamethasone	Dexamethasone results in increased expression of ABCB1 mRNA	16303967
D003907	Dexamethasone	Dexamethasone results in decreased expression of ABCB1 mRNA	20607812
D003907	Dexamethasone	Dexamethasone results in increased expression of ABCB1 protein	17015168
C025527	diacetolol	diacetolol binds to ABCB1 protein	10783826
C100261	diacetyldiphenylurea bisguanylhydrazone	"diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mRNA]"	23470866
C028009	diallyl disulfide	diallyl disulfide results in increased expression of ABCB1 mRNA	22397993
C042577	diallyl trisulfide	diallyl trisulfide results in decreased expression of ABCB1 protein	24788927
C042577	diallyl trisulfide	diallyl trisulfide results in increased expression of ABCB1 mRNA	22397993
D016190	Carboplatin	Carboplatin results in decreased expression of ABCB1 mRNA	27692344
D016190	Carboplatin	Carboplatin results in decreased expression of ABCB1 protein	27692344
D003976	Diazinon	ABCB1 protein results in decreased susceptibility to Diazinon	21127835
D003976	Diazinon	ABCB1 protein results in increased export of Diazinon	16221533
D003976	Diazinon	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	Diazinon affects the reaction [ABCB1 protein results in increased transport of Digoxin]	16221533
D003976	Diazinon	Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]	16221533
D003976	Diazinon	Diazinon inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon results in decreased activity of ABCB1 protein	21783720
D003976	Diazinon	Diazinon results in increased activity of ABCB1 protein	16221533
D003976	Diazinon	Diazinon results in increased expression of ABCB1 protein	16221533\|2112783
D003976	Diazinon	Sodium Azide inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	valspodar inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	Diazinon results in increased expression of ABCB1 mRNA	16221533
D003976	Diazinon	Diazinon results in increased expression of ABCB1 protein	16221533
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene results in increased expression of ABCB1 mRNA"	15566942
D002945	Cisplatin	ABCB1 affects the reaction [HIF1A affects the susceptibility to Cisplatin]	21964646
D002945	Cisplatin	ABCB1 affects the susceptibility to Cisplatin	15756446
D002945	Cisplatin	ABCB1 gene polymorphism affects the susceptibility to Cisplatin	16785472
D002945	Cisplatin	ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]	21332314
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]	22269388
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of and results in increased cleavage of CASP3 protein]	22269388
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of CASP9 protein]	22269388
D002945	Cisplatin	ABCB1 protein promotes the reaction [Cisplatin results in increased expression of TRP53 protein]	22269388
D002945	Cisplatin	ABCB1 protein results in decreased susceptibility to Cisplatin	15990222\|2226938
D002945	Cisplatin	Cisplatin promotes the reaction [[APEX1 protein modified form promotes the reaction [YBX1 protein binds to EP300 protein]] which binds to ABCB1 promoter]	20856196
D002945	Cisplatin	[Cisplatin results in increased acetylation of APEX1 protein] promotes the reaction [APEX1 protein modified form binds to ABCB1 promoter]	20856196
D002945	Cisplatin	[Cisplatin results in increased acetylation of APEX1 protein] promotes the reaction [[APEX1 protein modified form binds to ABCB1 promoter] which results in increased expression of ABCB1 mRNA]	20856196\|2085619
D002945	Cisplatin	Cisplatin results in increased expression of ABCB1 mRNA	15650019
D002945	Cisplatin	Cisplatin results in increased expression of ABCB1 protein	15239124\|1565001
D002945	Cisplatin	[CXCL8 results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Cisplatin	21742513
D002945	Cisplatin	[CXCL8 results in increased expression of ABCB1 protein] which results in decreased susceptibility to Cisplatin	21742513
D002945	Cisplatin	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Cisplatin	21833476
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]	22269388
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of and results in increased cleavage of CASP3 protein]	22269388
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of CASP9 protein]	22269388
D002945	Cisplatin	ABCB1 protein promotes the reaction [Cisplatin results in increased expression of TRP53 protein]	22269388
D002945	Cisplatin	ABCB1 protein results in decreased susceptibility to Cisplatin	22269388
D002945	Cisplatin	ABCB1 protein results in decreased susceptibility to Cisplatin	11455017
D002945	Cisplatin	[Diethylnitrosamine co-treated with Cisplatin] results in increased expression of ABCB1 protein	11818250
D002945	Cisplatin	Cisplatin inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	24800945
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in decreased expression of ABCB1 mRNA	15710169
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of ABCB1 mRNA	15710169
D004004	Dichlororibofuranosylbenzimidazole	Dichlororibofuranosylbenzimidazole inhibits the reaction [mangiferin results in increased expression of ABCB1 protein]	20513373
D004004	Dichlororibofuranosylbenzimidazole	Dichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in increased expression of ABCB1 protein]	16121039
C000944	dicrotophos	dicrotophos results in decreased expression of ABCB1 mRNA	28302478
D018119	Stavudine	Stavudine results in increased expression of ABCB1 mRNA	18310046
D004026	Dieldrin	Dieldrin results in increased expression of ABCB1 mRNA	24464585
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate promotes the reaction [NR1I2 protein results in increased expression of ABCB1 mRNA]	17003290
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of ABCB1 mRNA	17003290
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Cisplatin] results in increased expression of ABCB1 protein	11818250
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Epirubicin] results in increased expression of ABCB1 protein	11818250
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of ABCB1 protein	11818250
D004054	Diethylstilbestrol	Diethylstilbestrol results in decreased expression of ABCB1 protein	16925584
D004074	Digitoxin	ABCB1 protein results in increased transport of Digitoxin	26708294
D004074	Digitoxin	Digitoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D004076	Digoxigenin	ABCB1 protein results in increased transport of Digoxigenin	26708294
D004077	Digoxin	[TNF protein results in increased expression of ABCB1 protein] which results in increased export of Digoxin	21104926
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of ALB mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of DAO mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of EBF3 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GABRQ mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GLRA1 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of KLK6 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of MAB21L2 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC10A4 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC18A2 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of TTR mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form results in increased susceptibility to Digoxin	25419811
D004077	Digoxin	ABCB1 mutant form results in increased susceptibility to Digoxin	16594604\|2318680
D004077	Digoxin	[ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin]	20510202
D004077	Digoxin	MYL9 protein modified form affects the reaction [ABCB1 protein affects the transport of Digoxin analog]	20510202
D004077	Digoxin	[Verapamil results in decreased activity of ABCB1 protein] which affects the transport of Digoxin	20510202
D004077	Digoxin	18alpha-glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
D004077	Digoxin	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 mRNA]	19647009
D004077	Digoxin	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
D004077	Digoxin	ABCB1 gene SNP affects the abundance of Digoxin	21311904
D004077	Digoxin	ABCB1 gene SNP affects the transport of Digoxin	17365992
D004077	Digoxin	ABCB1 protein affects the transport of Digoxin	15969931\|1950598
D004077	Digoxin	ABCB1 protein binds to and affects the metabolism of Digoxin	15856409
D004077	Digoxin	ABCB1 protein results in decreased uptake of Digoxin	10617675
D004077	Digoxin	ABCB1 protein results in increased export of Digoxin	16674925\|2688894
D004077	Digoxin	ABCB1 protein results in increased transport of Digoxin	10527640\|1123111
D004077	Digoxin	ABCB1 protein results in increased uptake of Digoxin	16904803
D004077	Digoxin	abietic acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	benidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Bepridil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	beta-pinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	Bisoprolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D004077	Digoxin	Capsaicin affects the reaction [ABCB1 protein results in increased export of Digoxin]	16674925
D004077	Digoxin	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100\|1667196
D004077	Digoxin	citronellal inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[citronellal results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D004077	Digoxin	citronellol inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[citronellol results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D004077	Digoxin	cucurbitacin I inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	Curcumin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
D004077	Digoxin	[Cyclosporine binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	dehydroandrographolide inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	Diazinon affects the reaction [ABCB1 protein results in increased transport of Digoxin]	16221533
D004077	Digoxin	Digoxin binds to ABCB1 protein	23976943
D004077	Digoxin	Digoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D004077	Digoxin	Digoxin results in increased expression of ABCB1 mRNA	19647009
D004077	Digoxin	Digoxin results in increased expression of ABCB1 protein	19647009
D004077	Digoxin	[Digoxin results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
D004077	Digoxin	Diltiazem inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Doxazosin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	efonidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	[Elacridar results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
D004077	Digoxin	Emodin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	Fusidic Acid inhibits the reaction [ABCB1 protein results in increased export of Digoxin]	26888941
D004077	Digoxin	gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	gingerol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
D004077	Digoxin	ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	Glycyrrhetinic Acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	"[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin"	25844889
D004077	Digoxin	Itraconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D004077	Digoxin	[Ketoconazole binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	Ketoconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D004077	Digoxin	Ketoconazole inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D004077	Digoxin	[Ketoconazole results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
D004077	Digoxin	KN 93 inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
D004077	Digoxin	manidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	mepirodipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Nicardipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	nilvadipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Nisoldipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[Plant Extracts results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D004077	Digoxin	Propranolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D004077	Digoxin	rhodioloside affects the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D004077	Digoxin	terpinolene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D004077	Digoxin	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
D004077	Digoxin	[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	10527640\|1189510
D004077	Digoxin	Verapamil inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
D004077	Digoxin	ABCB1 results in decreased uptake of Digoxin	20557448
D004077	Digoxin	Cyclosporine inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D004077	Digoxin	Verapamil inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D004077	Digoxin	ABCB1 protein affects the secretion of Digoxin	21240898\|2134128
D004077	Digoxin	ABCB1 protein results in increased transport of Digoxin	15276087
D004077	Digoxin	Acetaminophen promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	15276087
D004077	Digoxin	ABCB1 protein affects the metabolism of Digoxin	23104431
D002117	Calcitriol	Calcitriol results in decreased activity of ABCB1 protein	12387747
D002117	Calcitriol	Calcitriol results in increased expression of ABCB1 mRNA	12387747\|1946094
D002117	Calcitriol	Calcitriol results in increased expression of ABCB1 protein	26366751
D002117	Calcitriol	VDR protein promotes the reaction [Calcitriol results in increased expression of ABCB1 mRNA]	19460946
D004110	Diltiazem	Diltiazem inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C007220	dimethyl 2,3,5,6-tetrachloroterephthalate	"dimethyl 2,3,5,6-tetrachloroterephthalate results in increased expression of ABCB1 mRNA"	22819804
C510843	dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate	"dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate results in decreased expression of ABCB1 protein"	16937080
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of ABCB1 mRNA	17072980
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide affects the expression of ABCB1 mRNA	12843640
C019357	dioscin	dioscin results in decreased expression of ABCB1 mRNA	24680847
C019357	dioscin	dioscin results in decreased expression of ABCB1 protein	24680847
C019357	dioscin	dioscin results in decreased expression of ABCB1	24680847
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D004221	Disulfiram	Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	14978246
D004221	Disulfiram	Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]	14978246
D004221	Disulfiram	Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]	14978246
D004221	Disulfiram	Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]	14978246
D004221	Disulfiram	Disulfiram metabolite results in decreased activity of ABCB1 protein	16028354
D004221	Disulfiram	Disulfiram results in decreased activity of ABCB1 protein	10841824\|1497824
C067311	docetaxel	ABCB1 gene polymorphism affects the susceptibility to docetaxel	25648089
C067311	docetaxel	ABCB1 mRNA results in increased susceptibility to docetaxel	15239142
C067311	docetaxel	ABCB1 protein affects the reaction [EGFR protein results in decreased susceptibility to docetaxel]	24888374
C067311	docetaxel	ABCB1 protein results in decreased susceptibility to docetaxel	17284363\|2019614
C067311	docetaxel	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	20196146
C067311	docetaxel	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	20196146
C067311	docetaxel	docetaxel results in decreased expression of ABCB1 mRNA	22445862
C067311	docetaxel	[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB1 mRNA	19944135
C067311	docetaxel	[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB1 protein	19944135
C067311	docetaxel	[docetaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
C067311	docetaxel	docetaxel results in increased expression of ABCB1 mRNA	15239124
C067311	docetaxel	docetaxel results in increased expression of ABCB1 protein	15239124\|2004132
C067311	docetaxel	[docetaxel results in increased expression of TP53 mRNA] which results in decreased expression of ABCB1 mRNA	22445862
C067311	docetaxel	NR1I2 protein promotes the reaction [docetaxel results in increased expression of and results in increased activity of ABCB1 protein]	20041327
C067311	docetaxel	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	20196146
C067311	docetaxel	TP53 protein affects the reaction [docetaxel results in decreased expression of ABCB1 mRNA]	22445862
D004294	Domperidone	ABCB1 gene SNP affects the susceptibility to Domperidone	21063774
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of ALB mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of DAO mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of EBF3 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GABRQ mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GLRA1 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of KLK6 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of MAB21L2 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC10A4 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC18A2 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of TTR mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form results in increased susceptibility to doramectin	22834856\|2541981
C084101	doramectin	ABCB1 mutant form results in increased susceptibility to doramectin	23186803
C084101	doramectin	doramectin results in decreased expression of ABCB1 mRNA	20487225
C084101	doramectin	doramectin results in decreased expression of ABCB1 protein	20487225
D017292	Doxazosin	Doxazosin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004316	Doxepin	ABCB1 protein results in increased export of Doxepin	14550684
D004317	Doxorubicin	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Doxorubicin results in decreased secretion of Hydrocortisone]	10898547
D004317	Doxorubicin	ABCB1 protein affects the susceptibility to Doxorubicin	24975508
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	24975508
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15492788
D004317	Doxorubicin	"[2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein"	28987325
D004317	Doxorubicin	"5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]"	20438634\|2043863
D004317	Doxorubicin	ABCB1 affects the susceptibility to Doxorubicin	12174371
D004317	Doxorubicin	ABCB1 mRNA results in decreased susceptibility to Doxorubicin	15765123\|1604415
D004317	Doxorubicin	ABCB1 mRNA results in increased susceptibility to Doxorubicin	15239142
D004317	Doxorubicin	ABCB1 promoter modified form results in decreased susceptibility to Doxorubicin	16356834
D004317	Doxorubicin	ABCB1 protein affects the reaction [Doxorubicin results in decreased susceptibility to Paraquat]	23220037
D004317	Doxorubicin	ABCB1 protein affects the susceptibility to Doxorubicin	17085340\|2499863
D004317	Doxorubicin	ABCB1 protein affects the transport of Doxorubicin	16499877
D004317	Doxorubicin	ABCB1 protein results in decreased abundance of Doxorubicin	15861398
D004317	Doxorubicin	ABCB1 protein results in decreased export of Doxorubicin	16936711
D004317	Doxorubicin	ABCB1 protein results in decreased secretion of Doxorubicin	15967469
D004317	Doxorubicin	ABCB1 protein results in decreased susceptibility to Doxorubicin	11313874\|1135595
D004317	Doxorubicin	"[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]"	20438634
D004317	Doxorubicin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
D004317	Doxorubicin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]	20438634
D004317	Doxorubicin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]	20438634\|2043863
D004317	Doxorubicin	ABCB1 protein results in decreased uptake of Doxorubicin	17526808\|1794749
D004317	Doxorubicin	ABCB1 protein results in increased export of and results in decreased susceptibility to Doxorubicin	18829547
D004317	Doxorubicin	ABCB1 protein results in increased export of Doxorubicin	15112361\|1748387
D004317	Doxorubicin	ABCB1 protein results in increased transport of and affects the susceptibility to Doxorubicin	18461970
D004317	Doxorubicin	ABCB1 protein results in increased transport of Doxorubicin	12708479
D004317	Doxorubicin	ABCB1 protein results in increased uptake of Doxorubicin	27318188
D004317	Doxorubicin	ABCB1 results in decreased susceptibility to Doxorubicin	19232821
D004317	Doxorubicin	Acetaminophen promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808
D004317	Doxorubicin	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]	25824409
D004317	Doxorubicin	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]	25824409
D004317	Doxorubicin	Beclomethasone inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D004317	Doxorubicin	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
D004317	Doxorubicin	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]] which results in decreased susceptibility to Doxorubicin	12708479
D004317	Doxorubicin	[carvedilol results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
D004317	Doxorubicin	Chlorpyrifos inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	"CJX1, amlodipine derivative inhibits the reaction [ABCB1 protein results in decreased secretion of Doxorubicin]"	15967469
D004317	Doxorubicin	Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	22233293
D004317	Doxorubicin	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497\|7905786
D004317	Doxorubicin	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
D004317	Doxorubicin	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D004317	Doxorubicin	[Digoxin results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
D004317	Doxorubicin	Doxorubicin results in decreased expression of ABCB1 protein	25339540
D004317	Doxorubicin	Doxorubicin results in increased activity of ABCB1 protein	15501994\|1752680
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1	15736412
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 mRNA	16544145\|1693708
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 protein	15501994\|1657964
D004317	Doxorubicin	[Doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paraquat	23220037
D004317	Doxorubicin	Endosulfan inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D004317	Doxorubicin	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7905786
D004317	Doxorubicin	gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	25824409
D004317	Doxorubicin	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein	25824409
D004317	Doxorubicin	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein	25824409
D004317	Doxorubicin	Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15946544
D004317	Doxorubicin	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D004317	Doxorubicin	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D004317	Doxorubicin	hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	Ivermectin inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D004317	Doxorubicin	lapatinib inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to Doxorubicin]	18829547
D004317	Doxorubicin	meloxicam inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	15501994
D004317	Doxorubicin	meloxicam inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	15501994
D004317	Doxorubicin	Metformin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	21054339
D004317	Doxorubicin	Mometasone Furoate inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D004317	Doxorubicin	"N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]"	24321342
D004317	Doxorubicin	[Ouabain results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
D004317	Doxorubicin	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	21833476
D004317	Doxorubicin	Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D004317	Doxorubicin	Parathion inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	pluronic block copolymer p85 inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	16579640
D004317	Doxorubicin	psorospermin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7083125
D004317	Doxorubicin	[Quercetin co-treated with Doxorubicin] results in decreased expression of ABCB1 protein	25339540
D004317	Doxorubicin	Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D004317	Doxorubicin	Quercetin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	25687049
D004317	Doxorubicin	[RAB6C protein affects the expression of ABCB1 mRNA] which affects the susceptibility to Doxorubicin	18992151
D004317	Doxorubicin	[resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA	24161697
D004317	Doxorubicin	[[resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA] which results in increased uptake of Doxorubicin	24161697
D004317	Doxorubicin	[resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 mRNA	24926353
D004317	Doxorubicin	[resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein	24926353
D004317	Doxorubicin	[Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	20041327
D004317	Doxorubicin	Risperidone inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D004317	Doxorubicin	terameprocol inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	16544145
D004317	Doxorubicin	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Doxorubicin	21657271
D004317	Doxorubicin	[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin	16223781
D004317	Doxorubicin	tryptoquivaline inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	18829547
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
D004317	Doxorubicin	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497\|2223329
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808\|1794749
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
D004317	Doxorubicin	Verapamil inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	17526808
D004317	Doxorubicin	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
D004317	Doxorubicin	withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D004317	Doxorubicin	[Doxorubicin co-treated with polyisohexylcyanoacrylate] results in increased expression of ABCB1 mRNA	15826724
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 mRNA	15826724\|1971424
D004317	Doxorubicin	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]	15861398
D004317	Doxorubicin	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]	15861398
D004317	Doxorubicin	zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	19714248
D004317	Doxorubicin	ABCB1 protein results in decreased susceptibility to Doxorubicin	11455017
D004317	Doxorubicin	ABCB1 protein results in increased secretion of Doxorubicin	15937726
D004317	Doxorubicin	Doxorubicin affects the activity of ABCB1 protein	15937726
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 mRNA	12187937
D004317	Doxorubicin	Tamoxifen affects the reaction [ABCB1 protein results in increased secretion of Doxorubicin]	15937726
D004317	Doxorubicin	Tamoxifen inhibits the reaction [Doxorubicin affects the activity of ABCB1 protein]	15937726
D004317	Doxorubicin	ABCB1 protein results in decreased susceptibility to Doxorubicin	15906164
D004317	Doxorubicin	ABCB1 results in decreased susceptibility to Doxorubicin	18451141
D004318	Doxycycline	Doxycycline results in decreased expression of ABCB1 protein	11147995
C066425	efonidipine	efonidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C083501	Elacridar	Elacridar binds to and results in decreased activity of ABCB1 protein	23976943
C083501	Elacridar	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of amprenavir	23976943
C083501	Elacridar	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
C083501	Elacridar	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine	23976943
C083501	Elacridar	"Elacridar inhibits the reaction [ABCB1 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]"	20522663
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estriol]	15290871
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estrone]	15290871
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of Quinacrine]	16581945
C083501	Elacridar	Elacridar results in decreased activity of ABCB1 protein	15832500\|2584488
C083501	Elacridar	[Elacridar results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
C083501	Elacridar	Elacridar results in decreased export of [ABCB1 protein results in increased transport of Ethinyl Estradiol]	15290871
C083501	Elacridar	Elacridar results in decreased activity of ABCB1 protein	15860656\|1905331
C443359	emamectin	emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C443359	emamectin	emamectin results in decreased activity of ABCB1 protein	25865432
C108024	emamectin benzoate	emamectin benzoate results in increased expression of ABCB1 mRNA	17350696\|2186777
C108024	emamectin benzoate	emamectin benzoate results in decreased activity of ABCB1 protein	24316435
C468987	emodepside	ABCB1 protein affects the susceptibility to emodepside	25660379
D004642	Emodin	Emodin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004726	Endosulfan	Endosulfan results in increased activity of ABCB1 protein	17490606
D004726	Endosulfan	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Endosulfan]	17490606
D004726	Endosulfan	ABCB1 protein results in decreased susceptibility to Endosulfan	8917702
D004726	Endosulfan	ABCB1 protein results in increased export of Endosulfan	8917702
D004726	Endosulfan	Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	Diazinon promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	Endosulfan binds to ABCB1 protein	8917702
D004726	Endosulfan	[Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D004726	Endosulfan	[Endosulfan co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
D004726	Endosulfan	Endosulfan inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004726	Endosulfan	Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D004726	Endosulfan	Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	Endosulfan inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	Endosulfan metabolite results in decreased activity of ABCB1 protein	23169446
D004726	Endosulfan	Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	Endosulfan promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	Endosulfan results in decreased activity of ABCB1 protein	21783720
D004726	Endosulfan	phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	phosalone inhibits the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	propiconazole promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D004731	Endotoxins	Endotoxins results in decreased expression of ABCB1 protein	15740733
C040240	enkephalin-Leu, Ala(2)-melphalan methyl ester-	"ABCB1 protein affects the transport of enkephalin-Leu, Ala(2)-melphalan methyl ester- analog"	12134948\|1213494
C052904	enrofloxacin	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of enrofloxacin	24498193
D015251	Epirubicin	"3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]"	22914566
D015251	Epirubicin	ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D015251	Epirubicin	[Epirubicin analog co-treated with chrysophsin analog] results in increased expression of ABCB1 mRNA	26335193
D015251	Epirubicin	Epirubicin analog results in increased expression of ABCB1 mRNA	26335193
D015251	Epirubicin	[Epirubicin co-treated with chrysophsin] results in increased expression of ABCB1 mRNA	26335193
D015251	Epirubicin	Epirubicin results in increased expression of ABCB1 mRNA	22914566\|2386790
D015251	Epirubicin	formononetin inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]	23867903
D015251	Epirubicin	[Diethylnitrosamine co-treated with Epirubicin] results in increased expression of ABCB1 protein	11818250
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased expression of ABCB1 mRNA	18851785
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased expression of ABCB1 protein	20149610
C007619	eriodictyol	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
C007619	eriodictyol	eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D004917	Erythromycin	Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D004917	Erythromycin	Erythromycin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
D004917	Erythromycin	ABCB1 protein affects the transport of Erythromycin	15304119
D004917	Erythromycin	Erythromycin results in decreased activity of ABCB1 protein	11724091
D004918	Erythromycin Estolate	Erythromycin Estolate results in increased expression of ABCB1 mRNA	17522070
D004923	Erythrosine	Erythrosine results in decreased activity of ABCB1 protein	20041016
C025483	estradiol-17 beta-glucuronide	ABCB1 affects the susceptibility to estradiol-17 beta-glucuronide	9794924
C025483	estradiol-17 beta-glucuronide	ABCB1 results in increased transport of estradiol-17 beta-glucuronide	9794924
C025483	estradiol-17 beta-glucuronide	Daunorubicin inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
C025483	estradiol-17 beta-glucuronide	estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
C025483	estradiol-17 beta-glucuronide	estriol 17-glucuronide inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
D004964	Estriol	ABCB1 protein results in increased export of Estriol	15290871
D004964	Estriol	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estriol]	15290871
D004964	Estriol	Estriol results in increased expression of ABCB1 mRNA	15290871
D004964	Estriol	Estriol results in increased expression of ABCB1 protein	15290871
C012961	estriol-16 alpha-(beta-D-glucuronide)	estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
C035954	estriol 17-glucuronide	estriol 17-glucuronide inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
D004970	Estrone	ABCB1 protein results in increased export of Estrone	15290871
D004970	Estrone	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estrone]	15290871
D004970	Estrone	Estrone results in decreased expression of ABCB1 protein	16925584
D004970	Estrone	Estrone results in increased expression of ABCB1 mRNA	15290871
D004970	Estrone	Estrone results in increased expression of ABCB1 protein	15290871
D004997	Ethinyl Estradiol	ABCB1 protein results in increased export of Ethinyl Estradiol	15290871
D004997	Ethinyl Estradiol	Elacridar results in decreased export of [ABCB1 protein results in increased transport of Ethinyl Estradiol]	15290871
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ABCB1 mRNA	15290871\|2468590
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ABCB1 protein	15290871
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of and results in increased activity of ABCB1 protein	24685904
D004997	Ethinyl Estradiol	fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCB1 protein]	24685904
D005033	Ethylmaleimide	Ethylmaleimide results in decreased activity of ABCB1 protein	2900677
C026098	etiracetam	etiracetam results in decreased activity of ABCB1 protein	18408562
C026098	etiracetam	"Amino Acids, Peptides, and Proteins inhibits the reaction [etiracetam results in increased expression of ABCB1 protein]"	18473823
C026098	etiracetam	etiracetam results in increased expression of ABCB1 protein	18473823
D005047	Etoposide	ABCB1 exon polymorphism affects the susceptibility to Etoposide	12969965
D005047	Etoposide	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide	19562670
D005047	Etoposide	Etoposide results in increased expression of ABCB1 mRNA	27570640
D005047	Etoposide	Etoposide results in increased expression of ABCB1 protein	15239124\|2784090
D005047	Etoposide	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D005047	Etoposide	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D005047	Etoposide	[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to Etoposide	16733832
D005047	Etoposide	Verapamil inhibits the reaction [[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to Etoposide]	16733832
D000068338	Everolimus	ABCB1 polymorphism affects the susceptibility to Everolimus	27169792
C049639	evodiamine	evodiamine inhibits the reaction [TNF protein results in increased expression of ABCB1 protein]	15710601
D015025	Zearalenone	Zearalenone results in increased expression of ABCB1 mRNA	20607812
D005273	Fenbendazole	Fenbendazole affects the expression of ABCB1 mRNA	26366864
D011345	Fenofibrate	Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]	16316932
C052034	fenoxycarb	fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C052034	fenoxycarb	fenoxycarb results in decreased activity of ABCB1 protein	21783720
C017690	fenvalerate	fenvalerate results in increased activity of ABCB1 protein	17490606
C017690	fenvalerate	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of fenvalerate]	17490606
C017690	fenvalerate	fenvalerate inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C017690	fenvalerate	fenvalerate results in decreased activity of ABCB1 protein	21783720
C020326	ferric nitrilotriacetate	"ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased expression of ABCB1 protein]"	18385176
C020326	ferric nitrilotriacetate	ferric nitrilotriacetate inhibits the reaction [Razoxane results in increased expression of ABCB1 protein]	18385176
C093230	fexofenadine	ABCB1 protein results in decreased uptake of fexofenadine	18299336
C093230	fexofenadine	ABCB1 gene SNP affects the susceptibility to fexofenadine	15536457
C093230	fexofenadine	Itraconazole promotes the reaction [ABCB1 gene SNP affects the susceptibility to fexofenadine]	16084853
C093230	fexofenadine	Plant Extracts promotes the reaction [ABCB1 protein results in increased transport of fexofenadine]	12545142
C014558	flunixin meglumine	flunixin meglumine affects the expression of ABCB1 mRNA	26366864
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in decreased expression of ABCB1 mRNA	12387747
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased activity of ABCB1 protein	11960367
D015073	2-Acetylaminofluorene	[2-Acetylaminofluorene results in increased activity of AKT1 protein] which results in increased expression of ABCB1 mRNA	11960367
D015073	2-Acetylaminofluorene	[2-Acetylaminofluorene results in increased activity of RAC1 protein] which results in increased expression of ABCB1 mRNA	11960367
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 mRNA	11960367
D015073	2-Acetylaminofluorene	[RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]	11960367
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 mRNA	17303067
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 protein	17303067
D015073	2-Acetylaminofluorene	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]	17303067
D015073	2-Acetylaminofluorene	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 protein]	17303067
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 mRNA	17669244
D005456	Fluorescent Dyes	ABCB1 protein results in increased export of Fluorescent Dyes	27450509
D005456	Fluorescent Dyes	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
D005456	Fluorescent Dyes	Tobacco Smoke Pollution inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
C007740	fluorexon	ABCB1 protein results in increased export of fluorexon	16442095
C007740	fluorexon	ABCB1 protein results in increased secretion of fluorexon	12235267
C007740	fluorexon	Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	[carvedilol results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
C007740	fluorexon	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Mometasone Furoate inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
C053629	fluoroaluminum	fluoroaluminum promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
D005472	Fluorouracil	ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]	21332314
D005472	Fluorouracil	ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]	12576456
D005472	Fluorouracil	ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D005472	Fluorouracil	Fluorouracil results in decreased expression of ABCB1 mRNA	17287894
D005472	Fluorouracil	Fluorouracil results in increased expression of ABCB1 protein	15239124
D005472	Fluorouracil	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil	21833476
D005475	Flupenthixol	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7905786
D005475	Flupenthixol	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D005475	Flupenthixol	Flupenthixol analog results in decreased activity of ABCB1 protein	7905786
D005475	Flupenthixol	Flupenthixol analog results in decreased activity of ABCB1 protein mutant form	12711602
D005485	Flutamide	[Flutamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D005485	Flutamide	Flutamide results in increased expression of ABCB1 protein	20041327
D005485	Flutamide	NR1I2 protein promotes the reaction [Flutamide results in increased expression of and results in increased activity of ABCB1 protein]	20041327
D005485	Flutamide	Flutamide results in increased expression of ABCB1 mRNA	24136188
D000068298	Fluticasone	ABCB1 protein results in increased secretion of Fluticasone	22464980
D000068298	Fluticasone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
D000068298	Fluticasone	Fluticasone results in increased expression of ABCB1 protein	22464980
D000068298	Fluticasone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
D005505	Food Coloring Agents	Food Coloring Agents results in decreased activity of ABCB1 protein	18686201\|2004101
C007768	formononetin	Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]	23867903
C007768	formononetin	formononetin affects the activity of ABCB1 protein	15796199
C007768	formononetin	formononetin inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]	23867903
C007768	formononetin	formononetin results in increased expression of ABCB1 mRNA	23867903
C080222	FPEPIR regimen	FPEPIR regimen results in increased expression of ABCB1 mRNA	16026610
C080222	FPEPIR regimen	FPEPIR regimen results in increased expression of ABCB1 protein	16026610
C070081	fulvestrant	fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCB1 protein]	24685904
C070081	fulvestrant	fulvestrant inhibits the reaction [Genistein results in increased expression of ABCB1 protein]	24685904
C070081	fulvestrant	fulvestrant results in increased expression of ABCB1 protein	24685904
C056933	fumonisin B1	fumonisin B1 inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
D037341	Fumonisins	Fumonisins results in increased expression of ABCB1 mRNA	28082229
D005672	Fusidic Acid	Fusidic Acid inhibits the reaction [ABCB1 protein results in increased export of Digoxin]	26888941
C040029	gabapentin	gabapentin results in decreased activity of ABCB1 protein	18408562
C037032	galangin	galangin results in increased expression of ABCB1 mRNA	26238175
D005707	Gallic Acid	Gallic Acid results in decreased expression of ABCB1 protein	20513373
D005711	Gallopamil	Gallopamil binds to ABCB1 protein	10783826
D005711	Gallopamil	Gallopamil metabolite binds to ABCB1 protein	10783826
C052659	gambogic acid	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]	25824409
C052659	gambogic acid	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]	25824409
C052659	gambogic acid	gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	25824409
C052659	gambogic acid	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein	25824409
C052659	gambogic acid	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein	25824409
C018669	gamma-terpinene	gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D019833	Genistein	fulvestrant inhibits the reaction [Genistein results in increased expression of ABCB1 protein]	24685904
D019833	Genistein	Genistein results in increased expression of ABCB1 mRNA	24685904
D019833	Genistein	Genistein results in increased expression of ABCB1 protein	18634814
D019833	Genistein	Genistein results in increased expression of and results in increased activity of ABCB1 protein	24685904
D005839	Gentamicins	Gentamicins results in decreased expression of ABCB1 mRNA	20623750
C007845	gingerol	gingerol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in increased expression of ABCB1 mRNA	19034627
C477042	ginkgolide A	ginkgolide A results in increased expression of ABCB1 mRNA	19034627
C045856	ginkgolide B	ginkgolide B results in increased expression of ABCB1 mRNA	19034627\|2677566
C045856	ginkgolide B	NR1I2 protein affects the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]	26775663
C045856	ginkgolide B	sulforafan inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]	26775663
C407883	ginsenoside F2	ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D005897	Glafenine	Glafenine results in decreased expression of ABCB1 mRNA	24136188
C005004	glaucine	glaucine results in increased activity of ABCB1 protein	23273999
C018549	globotriaosylceramide	ABCB1 protein results in increased chemical synthesis of globotriaosylceramide	14662772
C018549	globotriaosylceramide	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
C018549	globotriaosylceramide	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
D005947	Glucose	Glucose results in decreased expression of ABCB1 protein	22363694
D005963	Glucosylceramides	ABCB1 protein results in increased chemical synthesis of Glucosylceramides	14662772
D005963	Glucosylceramides	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D005963	Glucosylceramides	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D005990	Glycerol	Glycerol affects the metabolism of and affects the localization of ABCB1 protein mutant form	22184139
D006034	Glycyrrhetinic Acid	Glycyrrhetinic Acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D006160	Guanosine Triphosphate	ABCB1 protein results in increased hydrolysis of Guanosine Triphosphate	2900677
D006220	Haloperidol	Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15946544
D006220	Haloperidol	Haloperidol results in decreased activity of ABCB1 protein	16810505
D006220	Haloperidol	Haloperidol results in decreased expression of ABCB1 mRNA	15946544
D006533	Heptachlor	Heptachlor results in increased expression of ABCB1 mRNA	24464585
C050426	huperzine A	ABCB1 protein results in increased transport of huperzine A	28587984
C050426	huperzine A	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
C050426	huperzine A	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA	19047049
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA	19047049
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]	19047049
D006820	Hyaluronic Acid	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]	19047049
D006820	Hyaluronic Acid	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]	19047049
D006820	Hyaluronic Acid	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]	19047049
C041642	hydramethylnon	hydramethylnon binds to ABCB1 protein	8917702
C041642	hydramethylnon	hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D006843	Hydrocarbons, Chlorinated	"ABCB1 gene polymorphism affects the metabolism of Hydrocarbons, Chlorinated"	20558393
D006843	Hydrocarbons, Chlorinated	"ABCB1 gene SNP affects the susceptibility to Hydrocarbons, Chlorinated"	26457621
D006854	Hydrocortisone	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Doxorubicin results in decreased secretion of Hydrocortisone]	10898547
D006854	Hydrocortisone	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Mitotane results in decreased secretion of Hydrocortisone]	10898547
D006854	Hydrocortisone	ABCB1 protein results in increased secretion of Hydrocortisone	22464980
D006854	Hydrocortisone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
D006854	Hydrocortisone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of ABCB1 mRNA	26519223
C058309	hypaconitine	ABCB1 protein results in increased transport of hypaconitine	23200901
C058309	hypaconitine	ABCB1 protein results in increased transport of hypaconitine	23200901
C058309	hypaconitine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
C058309	hypaconitine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
C001654	hyperforin	hyperforin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C001654	hyperforin	hyperforin results in increased expression of ABCB1	16005588
C001654	hyperforin	hyperforin results in increased expression of ABCB1 mRNA	24259679
C004965	hypericin	hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C004965	hypericin	hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C004965	hypericin	hypericin results in increased expression of ABCB1	16005588
D007052	Ibuprofen	Ibuprofen results in increased expression of ABCB1 mRNA	22559005
D007052	Ibuprofen	Ibuprofen results in decreased expression of ABCB1 mRNA	21872554
D007069	Ifosfamide	[Ifosfamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D007069	Ifosfamide	Ifosfamide results in increased expression of ABCB1 protein	20041327
D007069	Ifosfamide	NR1I2 protein promotes the reaction [Ifosfamide results in increased expression of ABCB1 protein]	20041327
D000068877	Imatinib Mesylate	ABCB1 protein affects the susceptibility to Imatinib Mesylate	28623111
D000068877	Imatinib Mesylate	ABCB1 protein results in decreased susceptibility to Imatinib Mesylate	24954033
D000068877	Imatinib Mesylate	Imatinib Mesylate results in increased expression of ABCB1 mRNA	15970668
D000068877	Imatinib Mesylate	Imatinib Mesylate results in increased expression of and results in increased activity of ABCB1 protein	15970668
D007099	Imipramine	Imipramine affects the expression of ABCB1 mRNA	18355885
C016517	indole-3-carbinol	indole-3-carbinol results in decreased expression of ABCB1	16082211
D007306	Insecticides	ABCB1 gene polymorphism affects the metabolism of Insecticides	20558393
D007306	Insecticides	Insecticides results in decreased activity of ABCB1 protein	23169446
D007461	Iodoacetates	[Sodium Azide co-treated with Iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ABCB1 mRNA	25613284
C051890	irinotecan	ABCB1 exon SNP affects the susceptibility to and affects the metabolism of irinotecan	15801936
C051890	irinotecan	ABCB1 gene polymorphism affects the susceptibility to irinotecan	12960109
C051890	irinotecan	ABCB1 protein affects the export of irinotecan	15655543
C051890	irinotecan	ABCB1 protein results in decreased susceptibility to irinotecan	16815871
C051890	irinotecan	ABCB1 protein results in increased export of irinotecan	16271446
C000603302	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate	"isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCB1 protein"	25844889
C000603302	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate	"[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin"	25844889
C015959	isosafrole	isosafrole results in increased expression of ABCB1 protein	8632764
D017964	Itraconazole	ABCB1 protein affects the transport of Itraconazole	15905803
D017964	Itraconazole	Itraconazole affects the activity of ABCB1 protein	15964336
D017964	Itraconazole	Itraconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D017964	Itraconazole	Itraconazole promotes the reaction [ABCB1 gene SNP affects the susceptibility to fexofenadine]	16084853
D017964	Itraconazole	Itraconazole results in decreased activity of ABCB1 protein	15905803\|1596993
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of ALB mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of DAO mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of EBF3 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GABRQ mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GLRA1 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of KLK6 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of MAB21L2 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC10A4 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC18A2 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of TTR mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form results in increased susceptibility to Ivermectin	22834856\|2541981
D007559	Ivermectin	ABCB1 mutant form results in increased susceptibility to Ivermectin	23186803
D007559	Ivermectin	ABCB1 protein affects the abundance of Ivermectin	20595473
D007559	Ivermectin	ABCB1 protein mutant form results in increased susceptibility to Ivermectin	22924731
D007559	Ivermectin	ABCB1 protein affects the susceptibility to Ivermectin	25660379
D007559	Ivermectin	ABCB1 gene polymorphism affects the abundance of Ivermectin	20595473
D007559	Ivermectin	ABCB1 gene polymorphism affects the susceptibility to Ivermectin	20630055
D007559	Ivermectin	Ivermectin binds to ABCB1 protein	8917702
D007559	Ivermectin	Ivermectin inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D007559	Ivermectin	Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
D007559	Ivermectin	Ivermectin results in decreased activity of ABCB1 protein	25865432
D007559	Ivermectin	ABCB1 protein affects the abundance of Ivermectin	20595473
D007559	Ivermectin	Ivermectin results in decreased activity of ABCB1 protein	24316435
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of ABCB1 mRNA	25961927
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in increased expression of ABCB1 mRNA	24796395
C410337	K 7174	K 7174 results in increased expression of ABCB1 mRNA	24086573
C006552	kaempferol	kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C006552	kaempferol	ABCB1 protein results in increased transport of kaempferol	15969930
C006552	kaempferol	kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
C006552	kaempferol	kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C011889	kavain	kavain results in increased activity of ABCB1 protein	16033948
C119620	kenpaullone	kenpaullone results in increased expression of ABCB1 protein	18624906
D007654	Ketoconazole	Ketoconazole results in decreased activity of ABCB1 protein	19754906
D007654	Ketoconazole	[Ketoconazole results in decreased activity of ABCB1 protein] which results in decreased transport of Technetium Tc 99m Sestamibi	19754906
D007654	Ketoconazole	Ketoconazole results in decreased expression of ABCB1 mRNA	22620706
D007654	Ketoconazole	ABCB1 protein results in increased transport of Ketoconazole	23976943
D007654	Ketoconazole	Ketoconazole binds to and results in decreased activity of ABCB1 protein	23976943
D007654	Ketoconazole	[Ketoconazole binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D007654	Ketoconazole	"Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]"	25542144
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]	16819505
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]	16819505
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	16819505\|2554214
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	16819505\|2062446
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCB1 protein]	21459122
D007654	Ketoconazole	Ketoconazole results in decreased activity of ABCB1 protein	10350002\|1596993
D007654	Ketoconazole	[Ketoconazole results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
D007654	Ketoconazole	Ketoconazole results in decreased expression of ABCB1 mRNA	17365992
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]	16819505
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]	16819505
D007654	Ketoconazole	Ketoconazole affects the expression of ABCB1 mRNA	18355885
C072105	KN 93	KN 93 inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
C072105	KN 93	KN 93 inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
C057416	KT 5720	KT 5720 results in decreased activity of ABCB1 protein	15725475
D007741	Labetalol	Labetalol binds to ABCB1 protein	10783826
D007790	Lactosylceramides	ABCB1 protein results in increased chemical synthesis of Lactosylceramides	14662772
D007790	Lactosylceramides	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
D007790	Lactosylceramides	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
C047781	lamotrigine	lamotrigine results in decreased activity of ABCB1 protein	18408562
D064747	Lansoprazole	ABCB1 affects the susceptibility to Lansoprazole	19238367
C490728	lapatinib	lapatinib inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to Doxorubicin]	18829547
C490728	lapatinib	lapatinib inhibits the reaction [azidoprazosin binds to ABCB1 protein]	18829547
C490728	lapatinib	lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18829547
D007854	Lead	ABCB1 gene polymorphism affects the abundance of Lead	25728017
C017461	lead nitrate	lead nitrate results in increased expression of ABCB1 protein	21526414
C052901	lemongrass oil	lemongrass oil affects the expression of ABCB1 mRNA	25976427
D001556	Lindane	Lindane results in increased expression of ABCB1 mRNA	24464585
D008070	Lipopolysaccharides	[Lipopolysaccharides co-treated with resveratrol] results in decreased expression of ABCB1 mRNA	26667767
D008070	Lipopolysaccharides	GCG protein inhibits the reaction [Lipopolysaccharides affects the localization of ABCB1 protein]	28842383
D008070	Lipopolysaccharides	GCG protein inhibits the reaction [Lipopolysaccharides results in decreased expression of ABCB1 mRNA]	28842383
D008070	Lipopolysaccharides	GCG protein inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased activity of ABCB1 protein]	28842383
D008070	Lipopolysaccharides	Lipopolysaccharides affects the localization of ABCB1 protein	28842383
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of ABCB1 mRNA	28842383
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of and results in decreased activity of ABCB1 protein	28842383
D018021	Lithium Chloride	Lithium Chloride results in increased expression of ABCB1 protein	18624906
D008095	Lithocholic Acid	Lithocholic Acid results in increased expression of ABCB1 mRNA	19460946
D008095	Lithocholic Acid	VDR protein promotes the reaction [Lithocholic Acid results in increased expression of ABCB1 mRNA]	19460946
D008130	Lomustine	Lomustine results in increased expression of ABCB1 protein	15239124
D008139	Loperamide	ABCB1 protein affects the susceptibility to Loperamide	25660379
D008139	Loperamide	ABCB1 protein results in increased transport of Loperamide	23976943
D008139	Loperamide	Loperamide binds to ABCB1 protein	23976943
D008139	Loperamide	ABCB1 protein results in increased transport of Loperamide	20604828
D017336	Loratadine	ABCB1 protein results in increased export of Loratadine	12584158
D008148	Lovastatin	ABCB1 protein results in increased transport of Lovastatin	15616150
D008148	Lovastatin	ABCB1 protein results in increased transport of Lovastatin analog	15616150
D008148	Lovastatin	Lovastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
D008148	Lovastatin	Lovastatin analog results in decreased activity of ABCB1 protein	15616150
C533860	macitentan	macitentan results in decreased expression of ABCB1 mRNA	28369585
D008274	Magnesium	Cadmium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Copper inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Magnesium results in increased activity of ABCB1 protein	2900677
D008274	Magnesium	[Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D008274	Magnesium	Nickel inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Zinc inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D058185	Magnetite Nanoparticles	ABCB1 mutant form promotes the reaction [Magnetite Nanoparticles results in increased susceptibility to Daunorubicin]	20957165
D058185	Magnetite Nanoparticles	[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of ABCB1 mRNA	22114476
D058185	Magnetite Nanoparticles	Daunorubicin promotes the reaction [Magnetite Nanoparticles results in decreased expression of ABCB1 protein]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]]	20957165\|2095716
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]]	20957165\|2095716
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form results in increased susceptibility to Daunorubicin]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [Daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]]	20957165\|2095716
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles results in decreased expression of ABCB1 mRNA	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles results in decreased expression of ABCB1 protein	20957165
D058185	Magnetite Nanoparticles	[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ABCB1 mRNA	26378955
D008345	Manganese	Manganese results in increased activity of ABCB1 protein	2900677
D008345	Manganese	[Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
C501277	Mangifera indica extract	Mangifera indica extract results in decreased expression of ABCB1 protein	20513373
C013592	mangiferin	Dichlororibofuranosylbenzimidazole inhibits the reaction [mangiferin results in increased expression of ABCB1 protein]	20513373
C013592	mangiferin	mangiferin results in increased expression of ABCB1 mRNA	20513373
C013592	mangiferin	mangiferin results in increased expression of ABCB1 protein	20513373
C054218	manidipine	manidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D008353	Mannitol	Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]	15327746
D008463	Mebendazole	Mebendazole results in decreased expression of ABCB1 mRNA	28606429
D008463	Mebendazole	Mebendazole results in decreased expression of ABCB1 protein	28606429
D015767	Mefloquine	ABCB1 protein binds to and affects the uptake of and affects the secretion of Mefloquine	17015054
D015767	Mefloquine	Mefloquine results in decreased activity of ABCB1 protein	17015054
D008550	Melatonin	Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein]	28223141
C065757	meloxicam	meloxicam inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	15501994
C065757	meloxicam	meloxicam inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	15501994
C050699	mepirodipine	mepirodipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of ABCB1 mRNA	22819804
D008627	Mercuric Chloride	Mercuric Chloride affects the expression of ABCB1 mRNA	17083914
D008627	Mercuric Chloride	Mercuric Chloride results in increased activity of ABCB1 protein	23690080
D008627	Mercuric Chloride	Mercuric Chloride results in increased activity of ABCB1 protein	22580103
D008628	Mercury	Mercury results in increased expression of ABCB1 protein	15084411
D008628	Mercury	ABCB1 gene SNP affects the susceptibility to and affects the abundance of Mercury	27262785
C019470	mesaconitine	ABCB1 protein results in increased transport of mesaconitine	23200901
C019470	mesaconitine	ABCB1 protein results in increased transport of mesaconitine	23200901
C019470	mesaconitine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
C019470	mesaconitine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
C521990	metazachlor	metazachlor results in increased activity of ABCB1 protein	18433974
D008687	Metformin	Metformin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	21054339
D008687	Metformin	Metformin inhibits the reaction [RELA protein results in increased expression of ABCB1 mRNA]	21054339
D008687	Metformin	Metformin inhibits the reaction [TNF protein results in increased expression of ABCB1 mRNA]	21054339
D008687	Metformin	Metformin inhibits the reaction [TNF protein results in increased expression of ABCB1 protein]	21054339
D008687	Metformin	Metformin results in decreased expression of ABCB1 mRNA	21054339
D008687	Metformin	Metformin results in decreased expression of ABCB1 protein	21054339
D008687	Metformin	PRKAA1 protein affects the reaction [Metformin results in decreased expression of ABCB1 protein]	21054339
D008691	Methadone	Methadone affects the activity of ABCB1 protein	19840843
D008691	Methadone	Methadone results in increased expression of ABCB1 protein	19840843
D008691	Methadone	ABCB1 protein affects the susceptibility to Methadone	15089813
D008691	Methadone	ABCB1 protein affects the transport of Methadone	15089813
D008694	Methamphetamine	Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein]	28223141
D008694	Methamphetamine	Methamphetamine results in decreased expression of ABCB1 protein	28223141
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 mRNA	24384915
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 protein	24384915
D008727	Methotrexate	ABCB1 gene polymorphism affects the reaction [Methotrexate results in decreased secretion of IFNG protein]	16321374
D008727	Methotrexate	ABCB1 gene polymorphism affects the reaction [Methotrexate results in decreased secretion of IL2 protein]	16321374
D008727	Methotrexate	ABCB1 gene polymorphism affects the reaction [Methotrexate results in decreased secretion of TNF protein]	16321374
D008727	Methotrexate	ABCB1 gene polymorphism affects the susceptibility to Methotrexate	16321374\|2210413
D008727	Methotrexate	ABCB1 gene polymorphism affects the susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008727	Methotrexate	ABCB1 gene SNP affects the susceptibility to Methotrexate	18381794\|2285935
D008727	Methotrexate	ABCB1 polymorphism results in increased susceptibility to Methotrexate	21887680
D008727	Methotrexate	ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]	12576456
D008727	Methotrexate	ABCB1 protein results in increased susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008727	Methotrexate	Methotrexate results in increased expression of ABCB1 mRNA	17982279\|2473698
D008727	Methotrexate	Methotrexate results in increased expression of ABCB1 protein	15239124\|2473698
D008727	Methotrexate	Vitamin B 12 inhibits the reaction [Methotrexate results in increased expression of ABCB1 mRNA]	17982279
D008727	Methotrexate	ABCB1 protein results in increased transport of Methotrexate	27377006
D008727	Methotrexate	resveratrol inhibits the reaction [ABCB1 protein results in increased transport of Methotrexate]	27377006
C406712	methoxyfenozide	ABCB1 protein results in increased transport of methoxyfenozide	26995013
C406712	methoxyfenozide	methoxyfenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
C439611	methoxy poly(ethylene glycol-co-epsilon-caprolactone)	[methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with resveratrol] results in decreased expression of ABCB1 protein	25392124
D008730	Methoxsalen	Methoxsalen results in decreased activity of ABCB1 protein	29079042
D008730	Methoxsalen	[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
D008730	Methoxsalen	Methoxsalen results in increased expression of ABCB1 mRNA	29079042
D008730	Methoxsalen	Verapamil inhibits the reaction [Methoxsalen results in decreased activity of ABCB1 protein]	29079042
D008730	Methoxsalen	Verapamil inhibits the reaction [[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of ABCB1 mRNA	11096091
D015104	3,4-Methylenedioxyamphetamine	"3,4-Methylenedioxyamphetamine results in increased activity of ABCB1 protein"	23273999
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of ABCB1 mRNA	17083914
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in decreased activity of ABCB1 protein"	14690877
D008743	Methyl Parathion	Methyl Parathion results in increased activity of ABCB1 protein	17490606
D008743	Methyl Parathion	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Methyl Parathion]	17490606
D008775	Methylprednisolone	ABCB1 gene polymorphism affects the susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008775	Methylprednisolone	ABCB1 protein results in increased secretion of Methylprednisolone	22464980
D008775	Methylprednisolone	ABCB1 protein results in increased susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008775	Methylprednisolone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
D008775	Methylprednisolone	Methylprednisolone results in increased expression of ABCB1 mRNA	22079615
D008775	Methylprednisolone	Methylprednisolone results in increased expression of ABCB1 protein	22079615\|2246498
D008775	Methylprednisolone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
C051786	metolachlor	ABCB1 protein affects the reaction [metolachlor results in increased susceptibility to Paclitaxel]	18433974
C051786	metolachlor	metolachlor results in increased activity of ABCB1 protein	18433974
D008801	Mexiletine	ABCB1 mutant form results in increased susceptibility to Mexiletine	16594604
D008825	Miconazole	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D008825	Miconazole	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D008874	Midazolam	Midazolam results in increased expression of ABCB1 protein	8632764
C059539	midostaurin	midostaurin results in decreased activity of ABCB1 protein	11836167
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of ALB mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of DAO mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of EBF3 mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of GABRQ mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of GLRA1 mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of KLK6 mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of MAB21L2 mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of SLC10A4 mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of SLC18A2 mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form affects the reaction [milbemycin affects the expression of TTR mRNA]	25419811
C027837	milbemycin	ABCB1 gene mutant form results in increased susceptibility to milbemycin	25419811
C027837	milbemycin	ABCB1 mutant form results in increased susceptibility to milbemycin	23186803
C027837	milbemycin	milbemycin results in decreased expression of ABCB1 protein	21458446
C039128	miltefosine	ABCB1 protein results in decreased susceptibility to miltefosine	11355955
C039128	miltefosine	miltefosine binds to and results in decreased activity of ABCB1 protein	11355955
C035133	mirtazapine	ABCB1 protein results in increased export of mirtazapine	14550684
D016685	Mitomycin	Mitomycin results in increased expression of ABCB1 protein	17934748
D008942	Mitoxantrone	Mitoxantrone results in increased expression of ABCB1 protein	15239124
C001801	mitragynine	mitragynine results in decreased activity of ABCB1 protein	24841968
C070571	ML 7	[ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin]	20510202
D000068656	Mometasone Furoate	Mometasone Furoate inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D000068656	Mometasone Furoate	Mometasone Furoate inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
D000068656	Mometasone Furoate	Mometasone Furoate inhibits the reaction [ABCB1 results in decreased susceptibility to Daunorubicin]	18310528
D009020	Morphine	ABCB1 affects the metabolism of Morphine	23748253
C420606	mulberroside A	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]	27918128
C420606	mulberroside A	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]	27918128
C420606	mulberroside A	mulberroside A results in decreased expression of ABCB1 mRNA	24530447
C420606	mulberroside A	mulberroside A results in decreased expression of and results in decreased activity of ABCB1 protein	24530447
C031448	musk ketone	musk ketone results in decreased activity of ABCB1 protein	26929997
C031448	musk ketone	[musk ketone results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C522231	N-(1-phenylcyclohexyl)-3-ethoxypropanamine	N-(1-phenylcyclohexyl)-3-ethoxypropanamine results in increased activity of ABCB1 protein	23273999
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA]	12926078
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of ABCB1 protein	23466342
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 mRNA	23466342
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 protein	21745461\|2346634
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ABCB1 mRNA	21745461
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
C037974	N-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine	"ABCB1 protein results in increased transport of N-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine"	21436125
C064769	N-acetylsphingosine	N-acetylsphingosine results in increased expression of ABCB1	11573427
D009270	Naloxone	Naloxone results in increased expression of ABCB1 mRNA	17522070
D019810	Sodium Azide	[Sodium Azide co-treated with Iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D019810	Sodium Azide	Sodium Azide inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D037742	Nanotubes, Carbon	"MYC protein inhibits the reaction [Nanotubes, Carbon results in decreased expression of ABCB1 protein]"	25461681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of and results in decreased activity of ABCB1 protein"	25461681
C031721	naphthalene	naphthalene results in decreased activity of ABCB1 protein	19135510
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of ABCB1 mRNA	17522070
D009288	Naproxen	Naproxen affects the expression of ABCB1 mRNA	18581209
C005273	naringenin	naringenin results in increased expression of ABCB1 mRNA	19148864
C101954	N-caproylsphingosine	ABCB1 protein results in decreased susceptibility to N-caproylsphingosine	21436125
C101954	N-caproylsphingosine	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to N-caproylsphingosine]	21436125
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	"ABCB1 protein affects the abundance of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide"	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	"ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide"	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	"N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide binds to and results in decreased activity of ABCB1 protein"	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	"N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]"	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	"[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide"	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	"Verapamil inhibits the reaction [ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide]"	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	"[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide"	24321342
D019888	Nelfinavir	ABCB1 gene SNP affects the susceptibility to Nelfinavir	16041239
D019888	Nelfinavir	ABCB1 intron SNP affects the susceptibility to Nelfinavir	16041239
D019888	Nelfinavir	ABCB1 protein affects the transport of Nelfinavir	16041239
C056041	nemadectin	nemadectin results in decreased expression of ABCB1 mRNA	20487225
C056041	nemadectin	nemadectin results in decreased expression of ABCB1 protein	20487225
D009529	Nicardipine	Nicardipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D009532	Nickel	Nickel inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D009532	Nickel	Nickel results in decreased expression of ABCB1 mRNA	25583101
C022838	nickel chloride	ABCB1 protein results in decreased susceptibility to nickel chloride	24448832
C022838	nickel chloride	alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
C022838	nickel chloride	fumonisin B1 inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
C022838	nickel chloride	nickel chloride results in increased expression of ABCB1 mRNA	24448832
C022838	nickel chloride	nickel chloride results in increased expression of ABCB1 protein	24448832
D009543	Nifedipine	Nifedipine results in increased expression of ABCB1 protein	8632764
D009544	Niflumic Acid	Niflumic Acid inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D009544	Niflumic Acid	Niflumic Acid results in decreased expression of ABCB1 protein	23523950
C035100	nilvadipine	nilvadipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C012655	nimesulide	nimesulide results in decreased expression of ABCB1 protein	21745461
C012655	nimesulide	nimesulide results in increased expression of ABCB1 mRNA	21745461
D015737	Nisoldipine	Nisoldipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C009074	N-n-propylnorapomorphine	Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
C009074	N-n-propylnorapomorphine	N-n-propylnorapomorphine results in increased expression of ABCB1 protein	9111066
C009074	N-n-propylnorapomorphine	Spiperone inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
C008661	nobiletin	nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
C008661	nobiletin	nobiletin promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
C069053	norathyriol	norathyriol results in increased expression of ABCB1 protein	20513373
D009640	Norethindrone	Norethindrone results in increased expression of ABCB1 mRNA	15290871
D016912	Levonorgestrel	Levonorgestrel results in increased expression of ABCB1 mRNA	15290871
D009661	Nortriptyline	ABCB1 exon SNP affects the susceptibility to Nortriptyline	12082591
C072936	notoginsenoside R1	notoginsenoside R1 results in increased expression of ABCB1 mRNA	25472953
C072936	notoginsenoside R1	NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mRNA]	25472953
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	21721528
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	21721528
C511311	NSC73306	tariquidar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C511311	NSC73306	valspodar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C511311	NSC73306	zosuquidar trihydrochloride analog inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	21721528
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	24800945
C511311	NSC73306	Cisplatin inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	24800945
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	21657271
C064976	O(6)-benzylguanine	[MGMT protein mutant form co-treated with ABCB1 protein] results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]	16733832
C410029	OC 144-093	OC 144-093 results in decreased activity of ABCB1 protein	11808870
D019319	Okadaic Acid	ABCB1 protein results in increased transport of Okadaic Acid	24374049
D019319	Okadaic Acid	ABCB1 protein results in increased transport of Okadaic Acid	24374049
C076029	olanzapine	olanzapine results in decreased activity of ABCB1 protein	16810505
C026209	oltipraz	oltipraz results in increased expression of ABCB1 mRNA	16837569
D009853	Omeprazole	Omeprazole binds to ABCB1 protein	10783826
D009853	Omeprazole	Omeprazole metabolite binds to ABCB1 protein	10783826
C009618	O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate	"O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in increased expression of ABCB1 mRNA"	15130596
C016340	o,p'-DDT	"o,p'-DDT results in decreased activity of ABCB1 protein"	23169446
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of ABCB1 mRNA"	24464585
C040764	ophiobolin A	ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D009943	Organophosphorus Compounds	ABCB1 gene SNP affects the susceptibility to Organophosphorus Compounds	26457621
D008939	Mitotane	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Mitotane results in decreased secretion of Hydrocortisone]	10898547
D008939	Mitotane	Mitotane inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
D008939	Mitotane	Mitotane results in decreased activity of ABCB1 protein	12015757\|1675220
D008939	Mitotane	Mitotane results in increased expression of ABCB1 mRNA	25542188
D008939	Mitotane	Mitotane results in increased expression of ABCB1 protein	25542188
C005290	oxybenzone	oxybenzone results in increased activity of ABCB1 protein	23690080
D010100	Oxygen	Oxygen deficiency results in decreased expression of ABCB1 mRNA	19695866
D010100	Oxygen	Oxygen deficiency results in increased expression of ABCB1 mRNA	15604272
D010100	Oxygen	pyrazolanthrone inhibits the reaction [Oxygen deficiency results in increased expression of ABCB1 mRNA]	15604272
D010100	Oxygen	Oxygen deficiency results in increased expression of ABCB1 protein	15604272
D010126	Ozone	Ozone results in increased expression of ABCB1 mRNA	16330353
D017239	Paclitaxel	6-OH-BDE-47 inhibits the reaction [ABCB1 protein results in increased export of Paclitaxel]	28031414
D017239	Paclitaxel	ABCB1 gene polymorphism affects the metabolism of Paclitaxel	15901749
D017239	Paclitaxel	ABCB1 gene SNP affects the susceptibility to Paclitaxel	16950614
D017239	Paclitaxel	ABCB1 mRNA results in decreased susceptibility to Paclitaxel	16322897
D017239	Paclitaxel	ABCB1 mRNA results in increased susceptibility to Paclitaxel	15239142
D017239	Paclitaxel	ABCB1 protein affects the reaction [acetochlor results in increased susceptibility to Paclitaxel]	18433974
D017239	Paclitaxel	ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]	18433974
D017239	Paclitaxel	ABCB1 protein affects the reaction [metolachlor results in increased susceptibility to Paclitaxel]	18433974
D017239	Paclitaxel	ABCB1 protein results in decreased susceptibility to Paclitaxel	15252144\|1599022
D017239	Paclitaxel	ABCB1 protein results in decreased uptake of Paclitaxel	10617675
D017239	Paclitaxel	ABCB1 protein results in increased export of and affects the susceptibility to Paclitaxel	18433974
D017239	Paclitaxel	ABCB1 protein results in increased export of Paclitaxel	28031414
D017239	Paclitaxel	ABCB1 protein results in increased transport of Paclitaxel	12708479
D017239	Paclitaxel	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
D017239	Paclitaxel	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]] which results in decreased susceptibility to Paclitaxel	12708479
D017239	Paclitaxel	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D017239	Paclitaxel	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D017239	Paclitaxel	crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293
D017239	Paclitaxel	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D017239	Paclitaxel	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D017239	Paclitaxel	[CXCL8 results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Paclitaxel	21742513
D017239	Paclitaxel	[CXCL8 results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paclitaxel	21742513
D017239	Paclitaxel	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D017239	Paclitaxel	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]	16819505
D017239	Paclitaxel	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]	16819505
D017239	Paclitaxel	NR1I2 protein promotes the reaction [Paclitaxel results in increased expression of and results in increased activity of ABCB1 protein]	20041327
D017239	Paclitaxel	Paclitaxel results in increased activity of ABCB1 protein	14512701
D017239	Paclitaxel	[Paclitaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D017239	Paclitaxel	Paclitaxel results in increased expression of ABCB1 mRNA	15650019\|1681950
D017239	Paclitaxel	Paclitaxel results in increased expression of ABCB1 protein	15650019\|1599022
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Cisplatin	21833476
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	21833476
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil	21833476
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine	21833476
D017239	Paclitaxel	propiconazole inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	25268938
D017239	Paclitaxel	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D017239	Paclitaxel	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Paclitaxel	21657271
D017239	Paclitaxel	[valspodar results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D017239	Paclitaxel	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293
D017239	Paclitaxel	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
D017239	Paclitaxel	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D017239	Paclitaxel	ABCB1 results in decreased susceptibility to Paclitaxel	10430060
D000068882	Paliperidone Palmitate	ABCB1 gene polymorphism affects the abundance of Paliperidone Palmitate	17541883
D000068882	Paliperidone Palmitate	ABCB1 protein affects the abundance of Paliperidone Palmitate	17541883
D000068882	Paliperidone Palmitate	ABCB1 protein results in increased transport of Paliperidone Palmitate	22691713
D000068882	Paliperidone Palmitate	Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D000068882	Paliperidone Palmitate	Paliperidone Palmitate results in decreased activity of ABCB1 protein	16810505\|1693671
D010269	Paraquat	ABCB1 protein affects the reaction [Doxorubicin results in decreased susceptibility to Paraquat]	23220037
D010269	Paraquat	ABCB1 protein results in increased export of and results in decreased susceptibility to Paraquat	25015657
D010269	Paraquat	[Doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paraquat	23220037
D010269	Paraquat	valspodar inhibits the reaction [ABCB1 protein results in increased export of Paraquat]	25015657
D010278	Parathion	ABCB1 protein results in decreased export of Parathion	8917702
D010278	Parathion	Parathion binds to ABCB1 protein	8917702
D010278	Parathion	Parathion inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D017374	Paroxetine	ABCB1 protein results in increased export of Paroxetine	14550684
D052638	Particulate Matter	acetovanillone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	CAT protein inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D052638	Particulate Matter	Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D052638	Particulate Matter	diphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein	18474546
D052638	Particulate Matter	[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
D052638	Particulate Matter	pyrazolanthrone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	TIMP3 protein inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	TNF protein affects the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	TNFRSF1A protein affects the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C513937	PB28 compound	PB28 compound results in decreased expression of ABCB1 protein	16891467
C513937	PB28 compound	PB28 compound results in decreased activity of ABCB1 protein	21229979
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in decreased expression of ABCB1 mRNA	23948077
D010416	Pentachlorophenol	Pentachlorophenol results in increased expression of ABCB1 mRNA	24486881
D010416	Pentachlorophenol	Pentachlorophenol results in decreased activity of ABCB1 protein	26929997
D010416	Pentachlorophenol	[Pentachlorophenol results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in decreased activity of ABCB1 protein	24014645
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased activity of ABCB1 protein	24014645
D010575	Pesticides	ABCB1 gene SNP affects the susceptibility to Pesticides	26457621
D010590	Phalloidine	Phalloidine results in decreased localization of ABCB1 protein	12169763
D010634	Phenobarbital	Phenobarbital affects the expression of ABCB1 mRNA	19159669
D010634	Phenobarbital	Phenobarbital results in decreased activity of ABCB1 protein	18408562
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCB1 mRNA	16837569\|1809403
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCB1 protein	16837569\|8632764
D010634	Phenobarbital	ABCB1 protein results in increased export of Phenobarbital	18063342
D010634	Phenobarbital	"Amino Acids, Peptides, and Proteins inhibits the reaction [Phenobarbital results in increased expression of ABCB1 protein]"	18473823
D010634	Phenobarbital	Phenobarbital results in decreased expression of ABCB1 mRNA	20607812
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCB1 protein	15569486\|1847382
D010636	Phenols	ABCB1 gene SNP results in increased susceptibility to Phenols analog	23874772
D010654	Phenylbutyrates	"[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of ABCB1 protein"	23284745
D010672	Phenytoin	ABCB1 protein affects the abundance of Phenytoin	10580886\|8001500
D010672	Phenytoin	ABCB1 protein affects the susceptibility to Phenytoin	14749549\|1737612
D010672	Phenytoin	ABCB1 protein results in increased metabolism of Phenytoin	16220110
D010672	Phenytoin	Phenytoin results in decreased activity of ABCB1 protein	18408562
D010672	Phenytoin	"Amino Acids, Peptides, and Proteins inhibits the reaction [Phenytoin results in increased expression of ABCB1 protein]"	18473823
D010672	Phenytoin	Phenytoin results in increased expression of ABCB1 protein	15569486\|1847382
C085059	phloxine	phloxine results in decreased activity of ABCB1 protein	20041016
C003117	phosalone	Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	Diazinon promotes the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	Endosulfan inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	[phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C003117	phosalone	[phosalone co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
C003117	phosalone	phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C003117	phosalone	phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	phosalone inhibits the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	phosalone inhibits the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	phosalone results in decreased activity of ABCB1 protein	21783720
C003117	phosalone	propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	propiconazole inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
D010713	Phosphatidylcholines	ABCB1 protein affects the export of Phosphatidylcholines	11147995
D010713	Phosphatidylcholines	ABCB1 protein affects the transport of Phosphatidylcholines	11745043
D010720	Phosphines	ABCB1 protein results in increased transport of Phosphines	9369495
C030090	phosphoramide mustard	phosphoramide mustard results in decreased expression of ABCB1 protein	27888070
D010795	Phthalic Acids	ABCB1 gene SNP results in increased susceptibility to Phthalic Acids	23874772
D010798	Phycocyanin	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]	17303067
D010798	Phycocyanin	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 protein]	17303067
C522973	PI103	PI103 results in decreased expression of ABCB1 mRNA	23300809
C008922	piperine	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]	23707768
C008922	piperine	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]	23707768
C008922	piperine	NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]	23707768
C008922	piperine	NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]	23707768
C008922	piperine	piperine results in increased expression of ABCB1 mRNA	23707768
C008922	piperine	piperine results in increased expression of ABCB1 protein	23707768
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCB1 mRNA	19710929
C108475	pitavastatin	ABCB1 protein affects the transport of pitavastatin	15955871
D010936	Plant Extracts	Plant Extracts affects the reaction [ABCB1 protein results in increased transport of Cyclosporine]	12545142
D010936	Plant Extracts	Plant Extracts promotes the reaction [ABCB1 protein results in increased transport of fexofenadine]	12545142
D010936	Plant Extracts	Plant Extracts results in decreased activity of ABCB1 protein	15627040\|1589037
D010936	Plant Extracts	[Plant Extracts results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D010936	Plant Extracts	Plant Extracts results in increased activity of ABCB1 protein	12545142\|2444630
D010936	Plant Extracts	Plant Extracts results in increased expression of ABCB1 mRNA	18439772
D010936	Plant Extracts	Plant Extracts results in increased expression of and results in increased activity of ABCB1 protein	18439772
D010936	Plant Extracts	Plant Extracts results in increased activity of ABCB1 protein	16033948
D028321	Plant Preparations	Plant Preparations analog results in increased expression of ABCB1 mRNA	19148864
D028321	Plant Preparations	Plant Preparations results in increased expression of ABCB1 mRNA	18047722
C013649	plastochromanol 8	plastochromanol 8 results in increased expression of ABCB1	15269186
C422648	pluronic block copolymer p85	pluronic block copolymer p85 inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	16579640
C422648	pluronic block copolymer p85	pluronic block copolymer p85 results in decreased folding of and results in decreased activity of ABCB1 protein	15648254
D053279	Polyacetylenes	Polyacetylenes results in decreased activity of ABCB1 protein	18425719
D011090	Polyenes	Polyenes results in decreased activity of ABCB1 protein	18425719
C057532	polyisohexylcyanoacrylate	[Doxorubicin co-treated with polyisohexylcyanoacrylate] results in increased expression of ABCB1 mRNA	15826724
D011192	Potassium Dichromate	Potassium Dichromate results in increased activity of ABCB1 protein	22580103
D017035	Pravastatin	ABCB1 protein results in increased transport of Pravastatin	15616150
D017035	Pravastatin	ABCB1 protein results in increased transport of Pravastatin analog	15616150
D011224	Prazosin	ABCB1 protein affects the transport of Prazosin	15616150
D011239	Prednisolone	ABCB1 results in decreased susceptibility to Prednisolone	18310528
D011241	Prednisone	ABCB1 protein results in increased secretion of Prednisone	22464980
D011241	Prednisone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
D011241	Prednisone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA	15914091
D011285	Pregnenolone Carbonitrile	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]	16819505
D011285	Pregnenolone Carbonitrile	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]	16819505
D011285	Pregnenolone Carbonitrile	NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]	16819505
D011285	Pregnenolone Carbonitrile	NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]	16819505
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA	16819505
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of ABCB1 protein	16819505
C045362	prochloraz	prochloraz results in increased expression of ABCB1 protein	27028005
C045362	prochloraz	prochloraz results in decreased activity of ABCB1 protein	11408081
D011374	Progesterone	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 mRNA]	19813763
D011374	Progesterone	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 protein]	19813763
D011374	Progesterone	Progesterone results in increased expression of ABCB1 mRNA	15290871\|1981376
D011374	Progesterone	Progesterone results in increased expression of ABCB1 protein	19813763
D011372	Progestins	Progestins results in increased expression of ABCB1 mRNA	19609016
C045950	propiconazole	Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	Diazinon promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	Endosulfan promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	phosalone inhibits the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	25268938
C045950	propiconazole	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C045950	propiconazole	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C045950	propiconazole	propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	propiconazole inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole metabolite affects the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C045950	propiconazole	propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	propiconazole promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	propiconazole promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole results in decreased activity of ABCB1 protein	21783720
C045950	propiconazole	propiconazole results in increased expression of ABCB1 mRNA	19409404
C045950	propiconazole	Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	Verapamil promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole results in increased expression of ABCB1 mRNA	19409404
D011433	Propranolol	Propranolol results in increased expression of ABCB1 mRNA	22559005
D011433	Propranolol	Propranolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D011433	Propranolol	Propranolol results in increased expression of ABCB1 mRNA	15276086
D011442	Proscillaridin	ABCB1 protein results in increased transport of Proscillaridin	26708294
D011442	Proscillaridin	Proscillaridin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C074191	prulifloxacin	ABCB1 protein affects the transport of prulifloxacin metabolite	15618759
C025543	psorospermin	psorospermin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7083125
D011691	Puromycin	ABCB1 protein results in increased transport of Puromycin	20018165
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [MAP3K1 protein results in increased expression of ABCB1 mRNA]	15604272
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Oxygen deficiency results in increased expression of ABCB1 mRNA]	15604272
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C020972	pyrrolidine dithiocarbamic acid	pyrrolidine dithiocarbamic acid inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
C020972	pyrrolidine dithiocarbamic acid	pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D011794	Quercetin	Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D011794	Quercetin	ABCB1 protein results in decreased abundance of Quercetin	15112361
D011794	Quercetin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]	20438634
D011794	Quercetin	ABCB1 protein results in increased transport of Quercetin	15969930
D011794	Quercetin	[Quercetin co-treated with Doxorubicin] results in decreased expression of ABCB1 protein	25339540
D011794	Quercetin	Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D011794	Quercetin	Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D011794	Quercetin	Quercetin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	25687049
D011794	Quercetin	Quercetin results in decreased expression of ABCB1	16059641\|2033595
D011794	Quercetin	Quercetin results in decreased expression of ABCB1 mRNA	18283591\|1862490
D011794	Quercetin	Quercetin results in decreased expression of ABCB1 protein	18283591\|1862490
D011794	Quercetin	Quercetin results in increased expression of ABCB1 mRNA	15266218\|2623817
D011794	Quercetin	Quercetin results in increased expression of ABCB1 protein	26366751
D011794	Quercetin	VDR promotes the reaction [Quercetin results in increased expression of ABCB1 mRNA]	26366751
D011794	Quercetin	Verapamil inhibits the reaction [ABCB1 protein results in decreased abundance of Quercetin]	15112361
D000069348	Quetiapine Fumarate	Quetiapine Fumarate results in decreased activity of ABCB1 protein	16810505
D011796	Quinacrine	ABCB1 protein results in increased transport of Quinacrine	16581945
D011796	Quinacrine	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of Quinacrine]	16581945
D011802	Quinidine	Quinidine results in decreased activity of ABCB1 protein	15666293
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to thiodicarb]	8898877
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to thiodicarb]	8644124
D011802	Quinidine	Quinidine results in decreased activity of ABCB1 protein	8898877
D011802	Quinidine	ABCB1 protein affects the transport of Quinidine	15616150
D011802	Quinidine	ABCB1 protein results in increased transport of Quinidine	23976943\|2699501
D011802	Quinidine	methoxyfenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
D011802	Quinidine	Quinidine binds to ABCB1 protein	23976943
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	20196146
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D011802	Quinidine	Quinidine results in decreased expression of ABCB1 protein	20196146
D011802	Quinidine	tebufenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
D011802	Quinidine	Quinidine binds to ABCB1 protein	19053318\|7808368
D011802	Quinidine	Quinidine results in decreased activity of ABCB1 protein	15089813
C454102	quinidinium	ABCB1 protein affects the uptake of quinidinium	11934808
C454102	quinidinium	ABCB1 protein results in increased transport of quinidinium	23104431\|2526893
C454102	quinidinium	bufalin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	cannogenin thevetoside inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Cardenolides inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Cymarine inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Digitoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Digoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Erythromycin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C454102	quinidinium	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C454102	quinidinium	propiconazole metabolite affects the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C454102	quinidinium	Proscillaridin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
D011803	Quinine	ABCB1 protein affects the uptake of Quinine analog	11934808
D019257	Quinpirole	Clozapine inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
D019257	Quinpirole	Quinpirole results in increased expression of ABCB1 protein	9111066
D019257	Quinpirole	Spiperone inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
D020849	Raloxifene Hydrochloride	ABCB1 protein affects the activity of Raloxifene Hydrochloride	16959878
D020849	Raloxifene Hydrochloride	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA	17096884
D020849	Raloxifene Hydrochloride	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein	17096884
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in decreased expression of ABCB1 mRNA	17096884
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in decreased expression of ABCB1 protein	17096884
D011929	Razoxane	ferric nitrilotriacetate inhibits the reaction [Razoxane results in increased expression of ABCB1 protein]	18385176
D011929	Razoxane	Razoxane results in increased expression of ABCB1 protein	18385176
C084826	rescinnamine	rescinnamine results in increased expression of ABCB1 mRNA	7476894
D012110	Reserpine	Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]	7476894
D012110	Reserpine	Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
D012110	Reserpine	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D012110	Reserpine	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D012110	Reserpine	Reserpine results in decreased activity of ABCB1 protein	19528478
D012110	Reserpine	Reserpine results in increased expression of ABCB1 mRNA	7476894
D012110	Reserpine	Reserpine results in increased expression of ABCB1 protein	8632764
D012110	Reserpine	Reserpine binds to ABCB1 protein	7808368
C059514	resveratrol	[Lipopolysaccharides co-treated with resveratrol] results in decreased expression of ABCB1 mRNA	26667767
C059514	resveratrol	[methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with resveratrol] results in decreased expression of ABCB1 protein	25392124
C059514	resveratrol	[resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA	24161697
C059514	resveratrol	[[resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA] which results in increased uptake of Doxorubicin	24161697
C059514	resveratrol	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]	19047049
C059514	resveratrol	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]	19047049
C059514	resveratrol	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]	19047049
C059514	resveratrol	resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]	19047049
C059514	resveratrol	resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	26394120
C059514	resveratrol	resveratrol results in decreased expression of ABCB1	19828106
C059514	resveratrol	resveratrol results in decreased expression of ABCB1 mRNA	19484992\|2639412
C059514	resveratrol	resveratrol results in decreased expression of ABCB1 protein	26394120
C059514	resveratrol	resveratrol results in increased expression of ABCB1 mRNA	18634814
C059514	resveratrol	resveratrol results in increased expression of ABCB1 protein	18634814
C059514	resveratrol	[resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 mRNA	24926353
C059514	resveratrol	[resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein	24926353
C059514	resveratrol	resveratrol results in decreased expression of ABCB1 mRNA	26394120
C059514	resveratrol	resveratrol results in decreased expression of ABCB1 protein	26394120
C059514	resveratrol	resveratrol inhibits the reaction [ABCB1 protein results in increased transport of Methotrexate]	27377006
D015474	Isotretinoin	[vorinostat co-treated with Isotretinoin] results in increased expression of ABCB1 mRNA	18769122
C003300	retrorsine	ABCB1 protein results in increased export of retrorsine	24799337
C003300	retrorsine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of retrorsine]	24799337
C120261	reversin 205	reversin 205 results in decreased activity of ABCB1 protein	26929997
C120261	reversin 205	[reversin 205 results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C009172	rhodioloside	rhodioloside affects the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
C013672	riddelliine	riddelliine results in increased expression of ABCB1 mRNA	18047722
D012293	Rifampin	[Rifampin co-treated with Colforsin] results in increased expression of ABCB1 protein	23164983
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	23164983
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	23164983
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	22620706
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	22620706
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	22559005
D012293	Rifampin	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]	23707768
D012293	Rifampin	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]	23707768
D012293	Rifampin	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	16819505\|2554214
D012293	Rifampin	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	16819505\|2062446
D012293	Rifampin	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]	27918128
D012293	Rifampin	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]	27918128
D012293	Rifampin	NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]	23707768
D012293	Rifampin	NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]	23707768
D012293	Rifampin	[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA	27918128
D012293	Rifampin	[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein	27918128
D012293	Rifampin	resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	26394120
D012293	Rifampin	Rifampin affects the activity of ABCB1 protein	15964336
D012293	Rifampin	[Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	20041327
D012293	Rifampin	Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D012293	Rifampin	[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein	20624464
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	11744607\|1472232
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	16819505\|1684240
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	25542188
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	25542188
C042734	rifaximin	rifaximin results in increased expression of ABCB1 mRNA	21141967
D018967	Risperidone	ABCB1 gene polymorphism affects the abundance of Risperidone	17541883\|1870899
D018967	Risperidone	ABCB1 gene polymorphism affects the susceptibility to Risperidone	17054409
D018967	Risperidone	ABCB1 protein affects the abundance of Risperidone	17541883\|1870899
D018967	Risperidone	ABCB1 protein affects the susceptibility to Risperidone	17054409
D018967	Risperidone	ABCB1 protein results in increased susceptibility to Risperidone	19997080
D018967	Risperidone	ABCB1 protein results in increased transport of Risperidone	22691713
D018967	Risperidone	Risperidone inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D018967	Risperidone	Risperidone results in decreased activity of ABCB1 protein	16810505\|1693671
D019438	Ritonavir	allicin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	hyperforin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C057006	Ro 21-5104	Ro 21-5104 results in increased expression of ABCB1 mRNA	25313206
C087123	romidepsin	ABCB1 protein binds to and affects the export of romidepsin	15634944
C087123	romidepsin	ABCB1 protein results in decreased susceptibility to romidepsin	16049968
C087123	romidepsin	romidepsin promotes the reaction [Tretinoin results in increased expression of ABCB1 mRNA]	16223781
C087123	romidepsin	romidepsin results in increased acetylation of ABCB1 promoter	16223781
C087123	romidepsin	romidepsin results in increased expression of ABCB1 mRNA	15833893\|1622378
C087123	romidepsin	romidepsin results in increased expression of ABCB1 protein	15634944\|1583389
C087123	romidepsin	[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin	16223781
C087123	romidepsin	[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 protein	16223781
C087123	romidepsin	Tretinoin promotes the reaction [romidepsin results in increased acetylation of ABCB1 promoter]	16223781
C087123	romidepsin	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
D012395	Rose Bengal	Rose Bengal results in decreased activity of ABCB1 protein	20041016
C106263	rostafuroxin	[LSS gene polymorphism co-treated with HSD3B1 gene polymorphism co-treated with ABCB1 gene polymorphism co-treated with ADD1 gene polymorphism co-treated with ADD3 gene polymorphism] affects the susceptibility to rostafuroxin	21106941
D012402	Rotenone	Rotenone affects the activity of ABCB1 protein	15796199
C046245	rubimaillin	"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mRNA]"	23466342
C046245	rubimaillin	rubimaillin inhibits the reaction [RELA protein results in increased expression of ABCB1 protein]	23466342
C046245	rubimaillin	rubimaillin results in decreased expression of ABCB1 mRNA	23466342
C046245	rubimaillin	rubimaillin results in decreased expression of ABCB1 protein	23466342
D019258	Saquinavir	ABCB1 protein affects the export of Saquinavir	15832500
D019258	Saquinavir	ABCB1 protein results in increased export of Saquinavir	18535159
D012524	Sarin	Sarin results in decreased expression of ABCB1 mRNA	19522546
D012530	Saxitoxin	Saxitoxin affects the activity of ABCB1 protein	29128272
D012530	Saxitoxin	[Thioctic Acid co-treated with Saxitoxin] affects the activity of ABCB1 protein	29128272
D012601	Scopolamine Hydrobromide	Scopolamine Hydrobromide results in decreased expression of ABCB1 mRNA	12818353
C548487	secomilbemycin D	secomilbemycin D results in decreased expression of ABCB1 protein	21458446
D020280	Sertraline	Sertraline results in increased activity of ABCB1 protein	23273999
D012717	Sesquiterpenes	Sesquiterpenes analog binds to and affects the activity of ABCB1 protein	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of Colchicine]	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of tetramethylrosamine]	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Daunorubicin]	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	15466210
D019821	Simvastatin	ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Simvastatin]	19802823
D019821	Simvastatin	ABCB1 polymorphism affects the susceptibility to Simvastatin	16321621\|1989155
D019821	Simvastatin	ABCB1 protein results in increased transport of Simvastatin	15616150
D019821	Simvastatin	Simvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
D019821	Simvastatin	Simvastatin analog results in decreased activity of ABCB1 protein	15616150
D019821	Simvastatin	ABCB1 results in increased transport of Simvastatin	19802823
D020123	Sirolimus	ABCB1 protein affects the metabolism of Sirolimus	15707415\|1576009
D020123	Sirolimus	ABCB1 protein affects the transport of Sirolimus	15964407
C504100	S-methyl N,N-diethylthiocarbamate sulfone	"S-methyl N,N-diethylthiocarbamate sulfone results in decreased activity of ABCB1 protein"	16028354
C073220	S-methyl N,N-diethylthiolcarbamate sulfoxide	"S-methyl N,N-diethylthiolcarbamate sulfoxide results in decreased activity of ABCB1 protein"	16028354
D012906	Smoke	Smoke results in decreased activity of ABCB1 protein	19135510
C534922	SNX 2112	SNX 2112 results in decreased expression of and results in decreased activity of ABCB1 protein	23777986
C017947	sodium arsenite	Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCB1 mRNA]	1967174
C017947	sodium arsenite	Dichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in increased expression of ABCB1 protein]	16121039
C017947	sodium arsenite	sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]	16121039
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 mRNA	1967174
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 protein	16121039\|1967174
C017947	sodium arsenite	[sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine	1967174
C017947	sodium arsenite	[Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]	16121039
C017947	sodium arsenite	ABCB1 protein results in increased secretion of sodium arsenite	28472378
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 mRNA	15694464
C017947	sodium arsenite	ABCB1 protein results in decreased susceptibility to sodium arsenite	11455017
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 mRNA	11408547\|1145501
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 protein	11455017
D013015	Sotalol	ABCB1 protein results in increased transport of Sotalol	16671962
D013015	Sotalol	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Sotalol]	16671962
D013134	Spiperone	Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
D013134	Spiperone	Spiperone inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
D013134	Spiperone	Spiperone inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
D013148	Spironolactone	Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCB1 protein]	21459122
D013148	Spironolactone	NR1I2 affects the reaction [Spironolactone results in increased expression of ABCB1 protein]	21459122
D013148	Spironolactone	Spironolactone results in increased expression of ABCB1 mRNA	21459122
D013148	Spironolactone	Spironolactone results in increased expression of ABCB1 protein	21459122
C100355	SR 12813	[SR 12813 results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	19746521
C100355	SR 12813	SR 12813 results in increased expression of ABCB1 mRNA	19746521
D013327	Strophanthidin	ABCB1 protein results in increased transport of Strophanthidin	26708294
D010042	Ouabain	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
D010042	Ouabain	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 mRNA]	19647009
D010042	Ouabain	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
D010042	Ouabain	KN 93 inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
D010042	Ouabain	Ouabain results in increased expression of ABCB1 mRNA	19647009
D010042	Ouabain	Ouabain results in increased expression of ABCB1 protein	19647009
D010042	Ouabain	[Ouabain results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
D003529	Cymarine	Cymarine inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D004113	Succimer	[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ABCB1 mRNA	26378955
C063871	sulfinosine	[sulfinosine co-treated with Curcumin] results in decreased expression of ABCB1 mRNA	18414057
C063871	sulfinosine	sulfinosine results in decreased expression of ABCB1 mRNA	18414057
C016766	sulforafan	sulforafan inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]	26775663
C016766	sulforafan	sulforafan results in decreased expression of ABCB1 mRNA	26775663
D013469	Sulpiride	ABCB1 protein results in increased transport of Sulpiride	28597291
D013469	Sulpiride	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Sulpiride]	28597291
C473478	sunitinib	sunitinib results in increased expression of ABCB1 mRNA	26797788
C473478	sunitinib	sunitinib results in increased expression of ABCB1 protein	26797788
C446685	systhane	systhane results in increased expression of ABCB1 mRNA	19409404
D016559	Tacrolimus	ABCB1 gene SNP results in increased susceptibility to Tacrolimus	12352921
D016559	Tacrolimus	ABCB1 protein affects the export of Tacrolimus	15919446\|1596433
D016559	Tacrolimus	ABCB1 protein affects the susceptibility to Tacrolimus	15919446
D016559	Tacrolimus	ABCB1 protein results in increased export of Tacrolimus	11920757
D016559	Tacrolimus	[Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]	1381629
D016559	Tacrolimus	Tacrolimus results in decreased activity of ABCB1 protein	20080907
D016559	Tacrolimus	[Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone	20080907
D016559	Tacrolimus	Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus]	11920757
C508967	tamarixetin	tamarixetin results in increased expression of ABCB1 mRNA	26238175
D013629	Tamoxifen	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Tamoxifen	19562670
D013629	Tamoxifen	NR1I2 protein promotes the reaction [Tamoxifen results in increased expression of ABCB1 protein]	20041327
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Estradiol results in decreased expression of ABCB1 protein]	16925584
D013629	Tamoxifen	[Tamoxifen results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D013629	Tamoxifen	Tamoxifen results in increased expression of ABCB1 protein	15290871\|2004132
D013629	Tamoxifen	Tamoxifen affects the reaction [ABCB1 protein results in increased secretion of Doxorubicin]	15937726
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Doxorubicin affects the activity of ABCB1 protein]	15937726
D013629	Tamoxifen	Tamoxifen binds to ABCB1 protein	7808368
C402343	tariquidar	tariquidar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C402343	tariquidar	tariquidar results in decreased activity of ABCB1 protein	15494300
C402343	tariquidar	tariquidar results in decreased activity of ABCB1 protein	21600273\|2728741
C402343	tariquidar	[tariquidar results in decreased activity of ABCB1 protein] which results in increased abundance of asoxime chloride	21600273
D013656	Taurocholic Acid	Taurocholic Acid results in increased expression of ABCB1 protein	11113123
C080625	taxane	taxane analog affects the activity of ABCB1 protein	15771464
D017256	Technetium Tc 99m Sestamibi	ABCB1 gene mutant form results in decreased transport of Technetium Tc 99m Sestamibi	19754906
D017256	Technetium Tc 99m Sestamibi	[Ketoconazole results in decreased activity of ABCB1 protein] which results in decreased transport of Technetium Tc 99m Sestamibi	19754906
D017256	Technetium Tc 99m Sestamibi	ABCB1 gene polymorphism affects the export of Technetium Tc 99m Sestamibi	16896007
C082026	tebufenozide	ABCB1 protein results in increased transport of tebufenozide	26995013
C082026	tebufenozide	tebufenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
C076852	terameprocol	terameprocol inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	16544145
C076852	terameprocol	terameprocol inhibits the reaction [SP1 protein results in increased expression of ABCB1 mRNA]	16544145
C076852	terameprocol	terameprocol results in decreased expression of ABCB1 mRNA	16544145
D016593	Terfenadine	ABCB1 protein affects the transport of Terfenadine	10350002
D016593	Terfenadine	ABCB1 protein affects the transport of Terfenadine analog	10350002
D016593	Terfenadine	Terfenadine results in decreased activity of ABCB1 protein	7905786
C021754	terics	terics results in decreased activity of ABCB1 protein	11408081
C027009	terpinolene	terpinolene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
C045037	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate affects the expression of ABCB1 mRNA	20189893
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in decreased activity of ABCB1 protein	24014645
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCB1 mRNA	16837569\|2010694
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of ABCB1 protein	22472606
D013752	Tetracycline	Tetracycline results in increased expression of ABCB1 mRNA	17522070\|1922454
D013755	Tetradecanoylphorbol Acetate	"5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]"	20438634\|2043863
D013755	Tetradecanoylphorbol Acetate	"[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]"	20438634
D013755	Tetradecanoylphorbol Acetate	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
D013755	Tetradecanoylphorbol Acetate	[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]	20438634\|2043863
D013755	Tetradecanoylphorbol Acetate	eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D013755	Tetradecanoylphorbol Acetate	kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D013755	Tetradecanoylphorbol Acetate	Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D013755	Tetradecanoylphorbol Acetate	withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ABCB1 mRNA	25613284
C412715	tetramethylrosamine	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of tetramethylrosamine]	15466210
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of cypermethrin]	17490606
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Endosulfan]	17490606
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of fenvalerate]	17490606
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Methyl Parathion]	17490606
C009438	tetrandrine	tetrandrine results in decreased expression of ABCB1	19840446
D013792	Thalidomide	Thalidomide results in decreased activity of ABCB1 protein	19840843
D013792	Thalidomide	Thalidomide results in decreased expression of ABCB1 mRNA	15920492
D013792	Thalidomide	Thalidomide results in decreased expression of ABCB1 protein	19840843
C022616	thiazolyl blue	thiazolyl blue results in decreased activity of ABCB1 protein	15451006
D013853	Thioacetamide	[Thioacetamide co-treated with Cyclosporine] results in increased expression of ABCB1 mRNA	15770714
D013853	Thioacetamide	Thioacetamide results in increased expression of ABCB1 mRNA	26222700
D013853	Thioacetamide	Thioacetamide results in increased expression of ABCB1 protein	26222700
D008063	Thioctic Acid	[Thioctic Acid co-treated with Saxitoxin] affects the activity of ABCB1 protein	29128272
C027971	thiodicarb	ABCB1 protein results in decreased susceptibility to thiodicarb	8898877
C027971	thiodicarb	ABCB1 protein results in increased export of and results in decreased susceptibility to thiodicarb	8644124
C027971	thiodicarb	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to thiodicarb]	8898877
C027971	thiodicarb	Quinidine inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to thiodicarb]	8644124
C059205	tiagabine	"Amino Acids, Peptides, and Proteins inhibits the reaction [tiagabine results in increased expression of ABCB1 protein]"	18473823
C059205	tiagabine	tiagabine results in increased expression of ABCB1 protein	18473823
D008625	Tiopronin	Tiopronin results in decreased expression of ABCB1 protein	21657271
D008625	Tiopronin	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Doxorubicin	21657271
D008625	Tiopronin	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Paclitaxel	21657271
D008625	Tiopronin	Tiopronin results in decreased stability of and results in decreased expression of ABCB1 mRNA	21657271
C402769	tipifarnib	ABCB1 gene SNP affects the susceptibility to tipifarnib	15122075
C009495	titanium dioxide	titanium dioxide inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1 mRNA]	25956639
C009495	titanium dioxide	titanium dioxide results in increased transport of ABCB1 protein	25956639
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of ABCB1 mRNA	28111298
C014225	tocophersolan	[methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with resveratrol] results in decreased expression of ABCB1 protein	25392124
C082032	tocotrienol, alpha	"tocotrienol, alpha results in increased expression of ABCB1"	15269186
C082089	tocotrienol, beta	"tocotrienol, beta results in increased expression of ABCB1"	15269186
C082097	tocotrienol, delta	"tocotrienol, delta results in increased expression of ABCB1"	15269186
D014050	Toluene	Toluene affects the expression of ABCB1 mRNA	18653662
C052342	topiramate	"Amino Acids, Peptides, and Proteins inhibits the reaction [topiramate results in increased expression of ABCB1 protein]"	18473823
C052342	topiramate	topiramate results in increased expression of ABCB1 protein	18473823
D019772	Topotecan	[chrysin results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
D019772	Topotecan	Topotecan results in increased expression of ABCB1 protein	20457140
D019772	Topotecan	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
D014212	Tretinoin	romidepsin promotes the reaction [Tretinoin results in increased expression of ABCB1 mRNA]	16223781
D014212	Tretinoin	"[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of ABCB1 protein"	23284745
D014212	Tretinoin	[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin	16223781
D014212	Tretinoin	[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 protein	16223781
D014212	Tretinoin	Tretinoin promotes the reaction [romidepsin results in increased acetylation of ABCB1 promoter]	16223781
D014212	Tretinoin	Tretinoin results in increased acetylation of ABCB1 promoter	16223781
D014212	Tretinoin	Tretinoin results in increased expression of ABCB1 mRNA	16223781
D014212	Tretinoin	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
C032910	triadimefon	triadimefon results in increased expression of ABCB1 mRNA	19409404
C032910	triadimefon	triadimefon results in decreased expression of ABCB1 mRNA	19409404
C011559	tributyltin	tributyltin results in increased activity of ABCB1 protein	23690080
C011559	tributyltin	tributyltin results in decreased expression of ABCB1 protein	26079211
D014241	Trichloroethylene	Trichloroethylene results in increased expression of ABCB1 mRNA	17905399
C012589	trichostatin A	[[decitabine co-treated with trichostatin A] affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531\|1867353
C012589	trichostatin A	decitabine promotes the reaction [trichostatin A results in increased expression of ABCB1 mRNA]	27570640
C012589	trichostatin A	[trichostatin A affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531\|1867353
C012589	trichostatin A	trichostatin A results in increased expression of ABCB1 mRNA	24935251\|2757064
D014268	Trifluoperazine	Trifluoperazine inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
D014268	Trifluoperazine	Trifluoperazine results in increased activity of ABCB1 protein	2900677
C114675	trimethoxybenzoylyohimbine	trimethoxybenzoylyohimbine results in increased expression of ABCB1 mRNA	7476894
D014302	Trinitrobenzenesulfonic Acid	Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]	18200517
D014302	Trinitrobenzenesulfonic Acid	Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA	18200517
C510683	tripeptide tyroservatide	tripeptide tyroservatide results in decreased expression of ABCB1 mRNA	18538471
C510683	tripeptide tyroservatide	tripeptide tyroservatide results in decreased expression of ABCB1 protein	18538471
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ABCB1 mRNA"	26179874
D014217	Troleandomycin	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D014217	Troleandomycin	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
C003330	trospium chloride	ABCB1 protein results in increased transport of trospium chloride	25466967
C003330	trospium chloride	valspodar inhibits the reaction [ABCB1 protein results in increased transport of trospium chloride]	25466967
C003330	trospium chloride	ABCB1 protein results in increased metabolism of trospium chloride	25466967
C046243	tryptanthrine	tryptanthrine binds to ABCB1 promoter	17482571
C046243	tryptanthrine	tryptanthrine results in decreased expression of ABCB1 mRNA	17482571
C046243	tryptanthrine	tryptanthrine results in decreased expression of ABCB1 protein	17482571
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	18829547
C012596	turmeric extract	ABCB1 affects the susceptibility to turmeric extract	15476675
C113580	U 0126	U 0126 results in decreased expression of ABCB1 mRNA	15526378
C113580	U 0126	U 0126 results in decreased expression of ABCB1 protein	15526378
C113580	U 0126	U 0126 results in increased expression of ABCB1 mRNA	24819614
D014520	Urethane	Urethane results in increased expression of ABCB1 mRNA	28818685
D014580	Ursodeoxycholic Acid	Ursodeoxycholic Acid results in increased expression of ABCB1 mRNA	16678547
C406224	valdecoxib	valdecoxib results in increased expression of ABCB1 mRNA	24136188
D014635	Valproic Acid	ABCB1 protein affects the susceptibility to Valproic Acid	14749549
D014635	Valproic Acid	Valproic Acid affects the expression of ABCB1 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased activity of ABCB1 protein	18408562
D014635	Valproic Acid	Valproic Acid results in decreased methylation of ABCB1 gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of ABCB1 mRNA	19949822\|2317975
D014635	Valproic Acid	Valproic Acid results in increased expression of ABCB1 protein	15569486
C070272	valspodar	valspodar results in decreased activity of ABCB1 protein	10898547
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Doxorubicin results in decreased secretion of Hydrocortisone]	10898547
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Mitotane results in decreased secretion of Hydrocortisone]	10898547
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	24975508
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine]	24975508
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15492788
C070272	valspodar	deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]	29174985
C070272	valspodar	valspodar affects the activity of ABCB1 protein	15788683
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to N-caproylsphingosine]	21436125
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of Paraquat]	25015657
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Bisoprolol]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of carvedilol]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Sotalol]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of trospium chloride]	25466967
C070272	valspodar	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
C070272	valspodar	valspodar results in decreased activity of ABCB1 protein	10997946\|1193480
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Xanthenes	21436125
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Cadmium]	21436125
C070272	valspodar	valspodar inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Xanthenes	21436125
C070272	valspodar	valspodar results in decreased activity of ABCB1 protein	11455017\|1238774
D014638	Vanadates	Vanadates results in decreased activity of ABCB1 protein	2900677
D014640	Vancomycin	Cilastatin inhibits the reaction [Vancomycin results in decreased expression of and affects the localization of ABCB1 protein]	28549670
D014640	Vancomycin	Vancomycin results in decreased expression of and affects the localization of ABCB1 protein	28549670
D001335	Vehicle Emissions	acetovanillone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	CAT protein inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D001335	Vehicle Emissions	Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D001335	Vehicle Emissions	diphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	pyrazolanthrone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	TIMP3 protein inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	TNF protein affects the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	TNFRSF1A protein affects the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein	18474546
D001335	Vehicle Emissions	[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
C521013	veliparib	ABCB1 protein results in increased transport of veliparib	21436403
D000069470	Venlafaxine Hydrochloride	Venlafaxine Hydrochloride results in increased expression of ABCB1 mRNA	17191263
D000069470	Venlafaxine Hydrochloride	ABCB1 protein results in increased export of Venlafaxine Hydrochloride	14550684
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	15666293
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which affects the transport of Digoxin	20510202
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	26929997
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
D014700	Verapamil	Verapamil inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D014700	Verapamil	Verapamil results in decreased expression of ABCB1 protein	23523950
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	24498193
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of enrofloxacin	24498193
D014700	Verapamil	ABCB1 protein results in increased transport of Verapamil	23976943\|2699501
D014700	Verapamil	Colchicine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Cyclosporine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Demecolcine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D014700	Verapamil	Diazinon promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
D014700	Verapamil	[Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D014700	Verapamil	[Endosulfan co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
D014700	Verapamil	[phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D014700	Verapamil	[phosalone co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
D014700	Verapamil	propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D014700	Verapamil	propiconazole promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
D014700	Verapamil	Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus]	11920757
D014700	Verapamil	Verapamil analog results in increased activity of ABCB1 protein mutant form	12711602
D014700	Verapamil	Verapamil binds to and results in decreased activity of ABCB1 protein	10527640\|1695987
D014700	Verapamil	[Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]	16121039
D014700	Verapamil	[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D014700	Verapamil	"[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide"	24321342
D014700	Verapamil	Verapamil inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCB1 protein]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]	15640379
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased abundance of Quercetin]	15112361
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497\|2223329
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808\|1794749
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	10527640\|1189510
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
D014700	Verapamil	"Verapamil inhibits the reaction [ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide]"	24321342
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Sulpiride]	28597291
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D014700	Verapamil	Verapamil inhibits the reaction [Acetaminophen results in increased activity of ABCB1 protein]	16930294\|1752680
D014700	Verapamil	Verapamil inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	17526808
D014700	Verapamil	Verapamil inhibits the reaction [Methoxsalen results in decreased activity of ABCB1 protein]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Verapamil promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
D014700	Verapamil	Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D014700	Verapamil	Verapamil promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	10571255\|1099794
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
D014700	Verapamil	Verapamil results in decreased expression of ABCB1 protein	22079615
D014700	Verapamil	Verapamil results in increased activity of ABCB1 protein	23273999\|2900677
D014700	Verapamil	Verapamil results in increased expression of ABCB1 mRNA	15276086\|7476894
D014700	Verapamil	Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]	15861398
D014700	Verapamil	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]	15861398
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	11408081
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	16026006
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D014700	Verapamil	Verapamil results in increased activity of ABCB1 protein	16033948
D014700	Verapamil	ABCB1 protein results in increased susceptibility to Verapamil	21657271
D014700	Verapamil	Verapamil binds to ABCB1 protein	10783826
D014700	Verapamil	Verapamil inhibits the reaction [[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to Etoposide]	16733832
D014700	Verapamil	Verapamil metabolite binds to ABCB1 protein	10783826
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	11724091\|2320090
C059141	verlukast	verlukast results in decreased activity of ABCB1 protein	16316932
D014747	Vinblastine	ABCB1 protein affects the uptake of Vinblastine	15640379
D014747	Vinblastine	ABCB1 protein results in decreased susceptibility to Vinblastine	11355955\|1572547
D014747	Vinblastine	ABCB1 protein results in increased secretion of Vinblastine	12235267
D014747	Vinblastine	ABCB1 protein results in increased transport of Vinblastine	12708479\|1622153
D014747	Vinblastine	Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
D014747	Vinblastine	[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine	12708479
D014747	Vinblastine	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]	15824923
D014747	Vinblastine	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D014747	Vinblastine	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D014747	Vinblastine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]	16221533
D014747	Vinblastine	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine	23976943
D014747	Vinblastine	Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein]	20041327
D014747	Vinblastine	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	15466210
D014747	Vinblastine	[sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine	1967174
D014747	Vinblastine	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]	15640379
D014747	Vinblastine	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
D014747	Vinblastine	Vinblastine binds to ABCB1 protein	23976943
D014747	Vinblastine	Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014747	Vinblastine	Vinblastine results in increased activity of ABCB1 protein mutant form	12711602
D014747	Vinblastine	[Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D014747	Vinblastine	Vinblastine results in increased expression of ABCB1 protein	20041327
D014747	Vinblastine	Vinblastine results in decreased activity of ABCB1 protein	11408081
D014747	Vinblastine	Vinblastine results in increased expression of ABCB1 mRNA	19501419
D014747	Vinblastine	ABCB1 protein results in decreased susceptibility to Vinblastine	11455017
D014748	Vinca Alkaloids	[cnidiadin results in decreased activity of ABCB1 protein] which results in increased susceptibility to Vinca Alkaloids	15824923
D014750	Vincristine	ABCB1 protein affects the susceptibility to Vincristine	24975508
D014750	Vincristine	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine]	24975508
D014750	Vincristine	ABCB1 protein affects the susceptibility to Vincristine	15645438
D014750	Vincristine	ABCB1 protein affects the uptake of Vincristine	11934808
D014750	Vincristine	ABCB1 protein results in decreased susceptibility to Vincristine	21344920\|7905786
D014750	Vincristine	ABCB1 protein results in decreased uptake of Vincristine	10617675
D014750	Vincristine	ABCB1 protein results in increased transport of Vincristine	16316932
D014750	Vincristine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D014750	Vincristine	[Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine	16925584
D014750	Vincristine	Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]	16316932
D014750	Vincristine	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D014750	Vincristine	[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine	11792417
D014750	Vincristine	NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein]	20041327
D014750	Vincristine	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine	21833476
D014750	Vincristine	[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB1 mRNA	19944135
D014750	Vincristine	[Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D014750	Vincristine	Vincristine results in increased expression of ABCB1 protein	15239124\|1603873
D014750	Vincristine	zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	21344920
D014750	Vincristine	ABCB1 results in decreased susceptibility to Vincristine	18310528
D014801	Vitamin A	"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]"	15327746
D014801	Vitamin A	Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]	15327746
D014801	Vitamin A	Vitamin A results in decreased expression of ABCB1 mRNA	15327746
D014805	Vitamin B 12	Vitamin B 12 inhibits the reaction [Methotrexate results in increased expression of ABCB1 mRNA]	17982279
D014805	Vitamin B 12	Vitamin B 12 results in decreased expression of ABCB1 mRNA	17982279
D014805	Vitamin B 12	Vitamin B 12 results in decreased expression of ABCB1 protein	17982279
C111237	vorinostat	[vorinostat co-treated with Isotretinoin] results in increased expression of ABCB1 mRNA	18769122
D014859	Warfarin	ABCB1 polymorphism affects the susceptibility to Warfarin	24092646\|2531278
D014859	Warfarin	ABCB1 protein affects the metabolism of Warfarin	21797966
C009684	withaferin A	withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634\|2043863
D014966	Xanthenes	ABCB1 protein results in increased export of Xanthenes	25862123
D014966	Xanthenes	ABCB1 protein results in increased transport of Xanthenes	21436125
D014966	Xanthenes	Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]	25862123
D014966	Xanthenes	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Xanthenes	21436125
D014966	Xanthenes	Xanthenes results in decreased activity of ABCB1 protein	18686201\|2004101
D014966	Xanthenes	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Xanthenes	21436125
D015016	Yohimbine	Yohimbine analog results in increased expression of ABCB1 mRNA	7476894
D015215	Zidovudine	Zidovudine results in increased expression of ABCB1 mRNA	15456083\|1831004
D015215	Zidovudine	Zidovudine results in increased expression of ABCB1 protein	9148857
D015032	Zinc	Zinc results in increased expression of ABCB1 protein	15084411
D015032	Zinc	Zinc inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
C016837	zinc chloride	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]	19714248
C016837	zinc chloride	zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	19714248
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride analog inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	21344920
C095179	zosuquidar trihydrochloride	"[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide"	24321342
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride results in decreased activity of ABCB1 protein	24321342

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005215	transporter activity	-	TAS	3022150
GO:0005515	protein binding	-	IPI	17088979 20711237
GO:0005524	ATP binding	-	IEA	-
GO:0008559	xenobiotic transmembrane transporting ATPase activity	-	TAS	-
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	-	TAS	3022150
GO:0090554	phosphatidylcholine-translocating ATPase activity	-	IDA	8898203
GO:0090555	phosphatidylethanolamine-translocating ATPase activity	-	IDA	8898203
GO:0099038	ceramide-translocating ATPase activity	-	IDA	8898203

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000086	G2/M transition of mitotic cell cycle	-	IDA	19384922
GO:0006855	drug transmembrane transport	-	IEA	-
GO:0042493	response to drug	-	TAS	3022150
GO:0042908	xenobiotic transport	-	IEA	-
GO:0045332	phospholipid translocation	-	IDA	8898203
GO:0047484	regulation of response to osmotic stress	-	IMP	7828597
GO:0055085	transmembrane transport	-	TAS	-
GO:0072089	stem cell proliferation	-	IMP	19384922
GO:0099040	ceramide translocation	-	IDA	8898203
GO:1901529	positive regulation of anion channel activity	-	IMP	7828597
GO:2001225	regulation of chloride transport	-	IMP	7828597

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005886	plasma membrane	-	TAS	-
GO:0009986	cell surface	-	IDA	19384922
GO:0016020	membrane	-	TAS	3022150
GO:0016021	integral component of membrane	-	IEA	-
GO:0016324	apical plasma membrane	-	IDA	8898203
GO:0070062	extracellular exosome	-	HDA	19056867 23533145

KEGG ID	KEGG Term
hsa02010	ABC transporters
hsa04976	Bile secretion

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	IEA
R-HSA-2161517	Abacavir transmembrane transport	IEA
R-HSA-2161522	Abacavir transport and metabolism	IEA
R-HSA-382551	Transport of small molecules	TAS
R-HSA-382556	ABC-family proteins mediated transport	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
27284701	Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT). (2016 Sep)	Zahari Z	Am J Drug Alcohol Abuse
17690563	In vitro P-glycoprotein-mediated transport of (R)-, (S)-, (R,S)-methadone, LAAM and their main metabolites. (2007)	Crettol S	Pharmacology
28867064	Increased DNA Methylation of ABCB1, CYP2D6, and OPRM1 Genes in Newborn Infants of Methadone-Maintained Opioid-Dependent Mothers. (2017 Nov)	McLaughlin P	J Pediatr
23333143	Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function. (2013 Feb 26)	Frelinger AL 3rd	J Am Coll Cardiol
14978246	The molecular basis of the action of disulfiram as a modulator of the multidrug resistance-linked ATP binding cassette transporters MDR1 (ABCB1) and MRP1 (ABCC1). (2004 Mar)	Sauna ZE	Mol Pharmacol
25556837	Methadone dose in heroin-dependent patients: role of clinical factors, comedications, genetic polymorphisms and enzyme activity. (2015 Jun)	Mouly S	Br J Clin Pharmacol
20201854	Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. (2010 Feb)	Yuferov V	Ann N Y Acad Sci
24086514	Association of polymorphisms in pharmacogenetic candidate genes (OPRD1, GAL, ABCB1, OPRM1) with opioid dependence in European population: a case-control study. (2013)	Beer B	PLoS One
18819034	Cyclooxygenase-2, multidrug resistance 1, and breast cancer resistance protein gene polymorphisms and inflammatory bowel disease in the Danish population. (2009)	Ostergaard M	Scand J Gastroenterol
19930591	Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study. (2009 Nov 21)	Andersen V	BMC Cancer
29793178	Nrf2/P-glycoprotein axis is associated with clinicopathological characteristics in colorectal cancer. (2018 May 21)	Sadeghi MR	Biomed Pharmacother
25918995	Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior. (2015 Apr 28)	Salvatore JE	Transl Psychiatry
15640379	Expression and function of ABCB1 and ABCG2 in human placental tissue. (2005 Apr)	Kolwankar D	Drug Metab Dispos
26109419	Polymorphisms in ATP-binding cassette transporter genes and interaction with diet and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study. (2015)	Kopp TI	Scand J Gastroenterol
18424454	ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence. (2008 Jul 15)	Levran O	Hum Mol Genet
17302182	Genetic risk profiles for cancer susceptibility and therapy response. (2007)	Bartsch H	Recent Results Cancer Res
24343710	Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention. (2014 May)	Nicol MR	J Clin Pharmacol
27096250	Pharmacokinetics of lamotrigine and its metabolite N-2-glucuronide: Influence of polymorphism of UDP-glucuronosyltransferases and drug transporters. (2016 Aug)	Milosheska D	Br J Clin Pharmacol
21589866	Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response. (2011 May 12)	Fonseca F	PLoS One
19250544	The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study. (2009 Feb 27)	Andersen V	BMC Med Genet
24933103	Associations of polymorphisms in DNA repair genes and MDR1 gene with chemotherapy response and survival of non-small cell lung cancer. (2014)	Du Y	PLoS One
28111265	P-gp/ABCB1 exerts differential impacts on brain and fetal exposure to norbuprenorphine. (2017 May)	Liao MZ	Pharmacol Res
27988838	Polymorphisms of Genes Encoding Multidrug Resistance Proteins as a Predictive Factor for Second-Line Docetaxel Therapy in Advanced Non-small Cell Lung Cancer. (2017 Jul)	Szczyrek M	Pathol Oncol Res
24956254	Pharmacogenomics of methadone maintenance treatment. (2014 May)	Somogyi AA	Pharmacogenomics
26327575	Impact of ABCB1 single-nucleotide polymorphisms on treatment outcomes with salmeterol/fluticasone combination therapy for stable chronic obstructive pulmonary disease. (2015 Oct)	Wang XW	Genet Test Mol Biomarkers
19506903	RASSF1A, APC, ESR1, ABCB1 and HOXC9, but not p16INK4A, DAPK1, PTEN and MT1G genes were frequently methylated in the stage I non-small cell lung cancer in China. (2009 Dec)	Lin Q	J Cancer Res Clin Oncol
21192135	High correlation between serum and cerebrospinal fluid olanzapine concentrations in patients with schizophrenia or schizoaffective disorder medicating with oral olanzapine as the only antipsychotic drug. (2011 Feb)	Skogh E	J Clin Psychopharmacol
17505995	ATP-binding cassette transporter ABCG2 (BCRP) and ABCB1 (MDR1) variants are not associated with disease susceptibility, disease phenotype response to medical therapy or need for surgeryin Hungarian patients with inflammatory bowel diseases. (2007 Jun)	Fischer S	Scand J Gastroenterol
26045716	Genetic susceptibility in childhood acute leukaemias: a systematic review. (2015)	Brisson GD	Ecancermedicalscience
22507978	Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study. (2012 Sep)	Park Y	Eur Heart J
27112608	[Relationship between ATP-binding cassette subfamily B member 1 and cytochrome P450 2C19 polymorphisms and the effect of clopidogrel post percutaneous coronary intervention in patients with acute coronary syndrome]. (2016 Apr 24)	Zhou CF	Zhonghua Xin Xue Guan Bing Za Zhi
29781244	OPRM1 influence on and effectiveness of an individualized treatment plan for prescription opioid use disorder patients. (2018 May 20)	Muriel J	Ann N Y Acad Sci
24911077	CYP2C9, VKORC1, CYP4F2, ABCB1 and F5 variants: influence on quality of long-term anticoagulation. (2014 Apr)	Nahar R	Pharmacol Rep
24682161	Effects of genetic polymorphisms of CYP2D6, CYP3A5, and ABCB1 on the steady-state plasma concentrations of aripiprazole and its active metabolite, dehydroaripiprazole, in Japanese patients with schizophrenia. (2014 Oct)	Suzuki T	Ther Drug Monit
22722500	Association study of 27 annotated genes for clozapine pharmacogenetics: validation of preexisting studies and identification of a new candidate gene, ABCB1, for treatment response. (2012 Aug)	Lee ST	J Clin Psychopharmacol
25012726	Association of ABCB1 polymorphisms with the efficacy of ondansetron in chemotherapy-induced nausea and vomiting. (2014 Aug 1)	He H	Clin Ther
26095139	Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT-PCR. (2015)	Toselli F	Xenobiotica
17178268	ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals. (2006 Dec)	Coller JK	Clin Pharmacol Ther
24892317	Genetic variants associated with addictive behavior in Colombian addicted and non-addicted to heroin or cocaine. (2013 Jan)	Isaza C	Colomb Med (Cali)
19370547	Differential involvement of P-glycoprotein (ABCB1) in permeability, tissue distribution, and antinociceptive activity of methadone, buprenorphine, and diprenorphine: in vitro and in vivo evaluation. (2009 Dec)	Hassan HE	J Pharm Sci