Gene: SNTG2

54221
G2SYN|SYN5
syntrophin gamma 2
protein-coding
2p25.3
Ensembl:ENSG00000172554 MIM:608715 Vega:OTTHUMG00000151370 UniprotKB:Q9NY99
NG_029707.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.367e-1 (AD)  3.853e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs4971371chr2:1080998 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RSPO30.617
SEMA3A0.599
PROC0.574
THEMIS0.57
GPR1500.565
IQCF30.564
MC4R0.561
ISLR0.554
NRG10.553
ARHGEF280.541

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PLA2G5-0.412
KCNJ16-0.383
SOX21-0.358
RLBP1-0.355
NWD1-0.352
HPSE2-0.343
WNT7B-0.338
PYGM-0.33
NXNL1-0.327
PIPOX-0.318

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of SNTG2 mRNA"21354444|2269881
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of SNTG2 mRNA25088246
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of SNTG2 mRNA"18648102
D000082AcetaminophenAcetaminophen affects the expression of SNTG2 mRNA25064622
D000082AcetaminophenAcetaminophen affects the expression of SNTG2 mRNA17562736
D020106AcrylamideAcrylamide results in increased expression of SNTG2 mRNA28959563
D000638AmiodaroneAmiodarone affects the expression of SNTG2 mRNA25064622
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of SNTG2 mRNA24449571
D001151ArsenicArsenic affects the methylation of SNTG2 gene25304211
C015001arsenitearsenite results in increased methylation of SNTG2 promoter23974009
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SNTG2 mRNA22228805
C006780bisphenol Abisphenol A results in decreased expression of SNTG2 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of SNTG2 gene28505145
C037123cadmium sulfatecadmium sulfate results in decreased expression of SNTG2 mRNA16221973
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of SNTG2 mRNA27339419
D002746ChlorpromazineChlorpromazine affects the expression of SNTG2 mRNA25064622
D003042CocaineCocaine results in decreased expression of SNTG2 mRNA27899881
D003042CocaineCocaine results in increased expression of SNTG2 mRNA17898221
D019327Copper SulfateCopper Sulfate results in increased expression of SNTG2 mRNA19549813
D016572CyclosporineCyclosporine affects the expression of SNTG2 mRNA25064622
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of SNTG2 mRNA28962523
D004041Dietary FatsDietary Fats affects the expression of SNTG2 mRNA19680557
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of SNTG2 mRNA24535843
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of SNTG2 mRNA21607683|2453584
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of SNTG2 mRNA25064622
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in decreased expression of SNTG2 mRNA21607683
C039281furanfuran results in increased expression of SNTG2 mRNA27387713
C004312glycidolglycidol results in increased expression of SNTG2 mRNA24915197
D017313FenretinideFenretinide results in decreased expression of SNTG2 mRNA28973697
D007649KetamineKetamine results in decreased expression of SNTG2 mRNA20080153
C008261lead acetatelead acetate results in increased expression of SNTG2 mRNA22613225
D008727MethotrexateMethotrexate results in decreased expression of SNTG2 mRNA24449571
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of SNTG2 mRNA"25620056
D009532NickelNickel results in decreased expression of SNTG2 mRNA25583101
D000073878Palm OilPalm Oil affects the expression of SNTG2 mRNA19680557
D010269ParaquatParaquat affects the expression of SNTG2 mRNA25064622
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of SNTG2 mRNA24535843
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SNTG2 mRNA]19482888
D010634PhenobarbitalPhenobarbital affects the expression of SNTG2 mRNA23091169
D010634PhenobarbitalPhenobarbital results in decreased expression of SNTG2 mRNA19482888
C006253pirinixic acid[pirinixic acid co-treated with PPARA] results in decreased expression of SNTG2 mRNA20813756
C006253pirinixic acidpirinixic acid results in decreased expression of SNTG2 mRNA20813756|2381119
D011374ProgesteroneProgesterone results in increased expression of SNTG2 mRNA22238285
C045950propiconazolepropiconazole results in decreased expression of SNTG2 mRNA21278054
D011441PropylthiouracilPropylthiouracil affects the expression of SNTG2 mRNA24780913
D012822Silicon DioxideSilicon Dioxide results in decreased expression of SNTG2 mRNA23221170
C016104sodium bichromatesodium bichromate results in decreased expression of SNTG2 mRNA22155349
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SNTG2 promoter]19654925
D013752TetracyclineTetracycline affects the expression of SNTG2 mRNA25064622
D013853ThioacetamideThioacetamide affects the expression of SNTG2 mRNA25064622
D013853ThioacetamideThioacetamide results in decreased expression of SNTG2 mRNA23411599
C012589trichostatin Atrichostatin A results in decreased expression of SNTG2 mRNA24935251
C057693troglitazonetroglitazone results in decreased expression of SNTG2 mRNA28973697
D014635Valproic AcidValproic Acid affects the expression of SNTG2 mRNA25064622
D014635Valproic AcidValproic Acid affects the expression of SNTG2 mRNA17292431
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of SNTG2 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003779actin binding-IEA-  
GO:0005198structural molecule activity-IEA-  
GO:0005515protein binding-IPI12429735  
GO:0030165PDZ domain binding-IPI17292328  
GO:0097109neuroligin family protein binding-IPI17292328  
GO ID GO Term Qualifier Evidence PubMed
GO:0007417central nervous system development-TAS10747910  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IEA-  
GO:0005856cytoskeleton-IEA-  
GO:0016013syntrophin complex-TAS10747910  
GO:0042383sarcolemma-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal