Gene: SPATA6L

55064
C9orf68|bA6J24.2
spermatogenesis associated 6 like
protein-coding
9p24.2-p24.1
Ensembl:ENSG00000106686 Vega:OTTHUMG00000019469 UniprotKB:Q8N4H0
NC_000009.12
SNP Mapped
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.248e-1 (AD)  8.929e-3 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF2730.813
KIAA07530.799
CCPG10.796
EFCAB70.794
ZC3H80.794
PLEKHA50.791
USP280.788
ANKRD420.784
FGFR1OP0.783
ZNF5490.782

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CTNNA3-0.356
KIF1C-0.34
BCAS1-0.34
OR4F5-0.335
MDFI-0.334
PAQR6-0.334
BCL7C-0.323
HEY2-0.323
RBP1-0.322
TGFB3-0.322

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Mercuric Chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPATA6L mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Mercuric Chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPATA6L mRNA"27188386
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of SPATA6L gene27153756
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of SPATA6L mRNA21298039
C006780bisphenol Abisphenol A results in decreased expression of SPATA6L mRNA25181051
D019256Cadmium ChlorideCadmium Chloride results in decreased methylation of SPATA6L promoter22457795
C069837fullerene C60fullerene C60 results in decreased expression of SPATA6L mRNA19167457
D008627Mercuric Chloride"[NOG protein co-treated with Mercuric Chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPATA6L mRNA"27188386
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in decreased expression of SPATA6L mRNA19564919
D008694MethamphetamineMethamphetamine results in decreased expression of SPATA6L mRNA19564919
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SPATA6L mRNA26011545
D009532NickelNickel results in decreased expression of SPATA6L mRNA24768652|2558310
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in decreased expression of SPATA6L mRNA19564919
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of SPATA6L mRNA25895662
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of SPATA6L mRNA"26743178
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of SPATA6L mRNA"26179874
D014520UrethaneUrethane results in decreased expression of SPATA6L mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of SPATA6L mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of SPATA6L mRNA28001369

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal