Gene: PRCC

5546
RCCP1|TPRC
papillary renal cell carcinoma (translocation-associated)
protein-coding
1q23.1
Ensembl:ENSG00000143294 MIM:179755 Vega:OTTHUMG00000041294 UniprotKB:Q92733
NG_008138.1
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.190e-1 (AD)  8.777e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ARFIP20.964
RNPS10.963
PEF10.96
CCAR20.959
STOML20.956
PSMD30.955
MLF20.954
TBRG40.954
SCYL10.954
ERAL10.953

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.76
OR4F29-0.711
KLRB1-0.322
MTRNR2L9-0.318
MTRNR2L6-0.313
EBF1-0.301
MTRNR2L10-0.301
TFPI2-0.294
IL18RAP-0.292
KCNJ15-0.29

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PRCC mRNA"15215175
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRCC mRNA"27188386
C0326424-aminophenylarsenoxide4-aminophenylarsenoxide binds to PRCC protein26598702
C0326424-aminophenylarsenoxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRCC protein]26598702
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRCC mRNA"27188386
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of PRCC mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PRCC mRNA]17585979
C006632arsenic trioxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRCC protein]26598702
C006780bisphenol Abisphenol A results in increased expression of PRCC mRNA26063408
C006780bisphenol Abisphenol A results in increased expression of PRCC mRNA25181051
C584509C646 compoundC646 compound results in decreased expression of PRCC mRNA26191083
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of PRCC mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PRCC mRNA]17585979
C000944dicrotophosdicrotophos results in increased expression of PRCC mRNA28302478
D019833GenisteinGenistein results in decreased expression of PRCC mRNA16705744
C492448ICG 001ICG 001 results in decreased expression of PRCC mRNA26191083
C045463leflunomideleflunomide results in decreased expression of PRCC mRNA28988120
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of PRCC mRNA26272509
C004925methylmercuric chloride"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRCC mRNA"27188386
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PRCC mRNA19710929
D010936Plant ExtractsPlant Extracts results in decreased expression of PRCC mRNA23557933
D014520UrethaneUrethane results in increased expression of PRCC mRNA28818685
D014635Valproic AcidValproic Acid results in increased expression of PRCC mRNA23179753

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI11717438  26871637  27107014  
GO ID GO Term Qualifier Evidence PubMed
GO:0000398mRNA splicing, via spliceosome-TAS-  
GO:0007093mitotic cell cycle checkpoint-IDA11717438  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA11717438  
GO:0005654nucleoplasm-TAS-  
GO:0016607nuclear speck-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-72163mRNA Splicing - Major PathwayTAS
R-HSA-72172mRNA SplicingTAS
R-HSA-72203Processing of Capped Intron-Containing Pre-mRNATAS
R-HSA-8953854Metabolism of RNATAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25027688Lymphopenia is an independent predictor of inferior outcome in papillary renal cell carcinoma. (2015 Sep)Mehrazin RUrol Oncol