Gene: SLC35E3

55508
BLOV1
solute carrier family 35 member E3
protein-coding
12q15
Ensembl:ENSG00000175782 Vega:OTTHUMG00000169282 UniprotKB:Q7Z769
NC_000012.12
SNP Mapped
0   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.810e-2 (AD)  4.994e-2 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg06533408chr12:69139618SLC35E31.170e-8Alcohol consumption der day27843151

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TUBGCP50.873
VEZT0.872
HLTF0.868
TSNAX0.853
TRPC10.852
PEX10.849
DHX570.846
ACADSB0.845
SLC25A160.845
FKTN0.845

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
C7orf61-0.451
CCDC102A-0.439
OR4F5-0.431
PPBP-0.415
MTRNR2L9-0.414
OR4F29-0.409
MTRNR2L6-0.404
CELSR1-0.402
FOXJ1-0.4
HSPB1-0.384

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4728291-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole"1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased expression of SLC35E3 mRNA"27071940
C4728291-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole"NFE2L2 gene mutant form inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased expression of SLC35E3 mRNA]"27071940
C0291412,2,5,7,8-pentamethyl-1-hydroxychroman"2,2,5,7,8-pentamethyl-1-hydroxychroman results in increased expression of SLC35E3 mRNA"21920950
D000082AcetaminophenAcetaminophen results in increased expression of SLC35E3 mRNA22230336
D016604Aflatoxin B1Aflatoxin B1 affects the expression of SLC35E3 protein20106945
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SLC35E3 mRNA21632981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SLC35E3 mRNA19770486
C006780bisphenol Abisphenol A affects the expression of SLC35E3 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of SLC35E3 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of SLC35E3 mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of SLC35E3 mRNA26079696
C584509C646 compoundC646 compound results in increased expression of SLC35E3 mRNA26191083
C030123coumarincoumarin results in increased expression of SLC35E3 mRNA18480146
D016572CyclosporineCyclosporine results in decreased expression of SLC35E3 mRNA25562108
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of SLC35E3 mRNA24317228
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of SLC35E3 mRNA27392435
D002945CisplatinCisplatin results in increased expression of SLC35E3 mRNA19561079|2739243
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of SLC35E3 mRNA22129741
D004785Environmental PollutantsEnvironmental Pollutants affects the expression of SLC35E3 mRNA19118595
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SLC35E3 mRNA22079256
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC35E3 mRNA17942748
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of SLC35E3 mRNA23649840
D005485FlutamideFlutamide results in increased expression of SLC35E3 mRNA24136188
D005557FormaldehydeFormaldehyde results in increased expression of SLC35E3 mRNA23649840
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of SLC35E3 mRNA22129741
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of SLC35E3 mRNA27392435
D007649KetamineKetamine results in decreased expression of SLC35E3 mRNA20080153
C045463leflunomideleflunomide results in increased expression of SLC35E3 mRNA24136188
D008627Mercuric ChlorideMercuric Chloride affects the expression of SLC35E3 mRNA20353558
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of SLC35E3 mRNA"26251327
C051752nefazodonenefazodone results in increased expression of SLC35E3 mRNA24136188
D009532NickelNickel results in decreased expression of SLC35E3 mRNA24768652
C012655nimesulidenimesulide results in increased expression of SLC35E3 mRNA24136188
D010936Plant ExtractsPlant Extracts results in increased expression of SLC35E3 mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SLC35E3 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of SLC35E3 mRNA22079256
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of SLC35E3 mRNA28903501
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in increased expression of SLC35E3 mRNA21427059
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in decreased expression of SLC35E3 mRNA"26680231
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SLC35E3 mRNA22574217
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SLC35E3 mRNA21570461|2468072
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC35E3 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SLC35E3 mRNA28922406
D013853ThioacetamideThioacetamide results in increased expression of SLC35E3 mRNA23411599
C009495titanium dioxidetitanium dioxide results in increased expression of SLC35E3 mRNA27760801
C011559tributyltintributyltin results in increased expression of SLC35E3 mRNA29191790
C080163trovafloxacintrovafloxacin results in decreased expression of SLC35E3 mRNA24136188
C406224valdecoxibvaldecoxib results in increased expression of SLC35E3 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of SLC35E3 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of SLC35E3 mRNA23179753
D014635Valproic AcidValproic Acid affects the expression of SLC35E3 mRNA17292431
D014635Valproic AcidValproic Acid results in increased expression of SLC35E3 mRNA20546886|2142705

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal