Gene: ZFP64

55734
ZNF338
ZFP64 zinc finger protein
protein-coding
20q13.2
Ensembl:ENSG00000020256 Vega:OTTHUMG00000032756 UniprotKB:Q9NPA5
NC_000020.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.097e-1 (AD)  5.103e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
POLR3A0.918
MYH100.909
STRIP10.908
RNF260.906
TBC1D250.906
METTL130.906
PI4KA0.906
MADD0.904
HERC10.904
EXTL30.902

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
YES1-0.492
HEY2-0.483
COPZ2-0.463
RAB13-0.461
MYL3-0.458
ASB4-0.458
RAI14-0.456
MYOM1-0.456
MTRNR2L10-0.45
WWTR1-0.447

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of ZFP64 mRNA"19114083
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of ZFP64 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of ZFP64 mRNA"21346803
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of ZFP64 mRNA"18648102
D000082AcetaminophenAcetaminophen affects the expression of ZFP64 mRNA17562736
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of ZFP64 mRNA24449571
D001280AtrazineAtrazine results in increased expression of ZFP64 mRNA25929836
D001374AzacitidineAzacitidine affects the methylation of ZFP64 promoter17546590
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ZFP64 mRNA22316170|2623829
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZFP64 mRNA"26238291
C006780bisphenol Abisphenol A results in decreased methylation of ZFP64 promoter27312807
C006780bisphenol Abisphenol A affects the methylation of ZFP64 promoter27415467
C006780bisphenol Abisphenol A results in increased expression of ZFP64 mRNA25181051
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of ZFP64 mRNA27392435
D002945CisplatinCisplatin results in increased expression of ZFP64 mRNA27392435
C000944dicrotophosdicrotophos results in increased expression of ZFP64 mRNA28302478
C118739entinostatentinostat results in increased expression of ZFP64 mRNA27188386
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of ZFP64 mRNA27392435
C544151jinfukangjinfukang results in increased expression of ZFP64 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of ZFP64 mRNA25307878
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of ZFP64 mRNA"25620056
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZFP64 mRNA"12756304
C006253pirinixic acidpirinixic acid results in decreased expression of ZFP64 mRNA25270620
C006253pirinixic acidpirinixic acid results in increased expression of ZFP64 mRNA18301758
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in decreased expression of ZFP64 mRNA21427059
D053260SootSoot results in increased expression of ZFP64 mRNA26551751
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ZFP64 mRNA21570461
D013853ThioacetamideThioacetamide results in increased expression of ZFP64 mRNA23411599
D014212TretinoinTretinoin results in decreased expression of ZFP64 mRNA23724009
D014635Valproic AcidValproic Acid affects the expression of ZFP64 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of ZFP64 mRNA22083351
D014635Valproic AcidValproic Acid results in increased expression of ZFP64 mRNA23179753
D014635Valproic AcidValproic Acid results in decreased expression of ZFP64 mRNA21427059
C111237vorinostatvorinostat results in decreased expression of ZFP64 mRNA22083351
D019287Zinc SulfateZinc Sulfate results in increased expression of ZFP64 mRNA12756304

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0005515protein binding-IPI25416956  27107014  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO:0010468regulation of gene expression-IBA21873635  
GO:0016569covalent chromatin modification-IBA21873635  
GO:0031060regulation of histone methylation-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleusCOLOCALIZES_WITHIBA21873635  
GO:0005634nucleus-IEA-  
GO:0035097histone methyltransferase complexCOLOCALIZES_WITHIBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27144936Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins. (2016 Jun)Livshits GJ Clin Endocrinol Metab