Gene: GLT8D1

55830
AD-017|MSTP139
glycosyltransferase 8 domain containing 1
protein-coding
3p21.1
Ensembl:ENSG00000016864 Vega:OTTHUMG00000158759 UniprotKB:Q68CQ7
NC_000003.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  6.990e-2 (ND)   (Frontal_Cortex)
8.227e-1 (AD)  4.460e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs115960994chr3:52697812 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
EIF2B10.936
TSN0.933
RBBP70.928
TAF110.928
XPNPEP10.927
NAE10.925
PSMC20.919
UNC500.917
SAR1A0.917
XRCC60.916

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.744
OR4F29-0.71
MTRNR2L6-0.297
MTRNR2L9-0.285
MTRNR2L10-0.258
C8orf74-0.245
MTRNR2L3-0.215
KLRB1-0.199
NKX6-1-0.197
ZBTB20-0.194

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of GLT8D1 mRNA"19114083
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of GLT8D1 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of GLT8D1 mRNA"21346803
D000082AcetaminophenAcetaminophen results in decreased expression of GLT8D1 mRNA11793227|2142099
D000082AcetaminophenAcetaminophen affects the expression of GLT8D1 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of GLT8D1 gene27153756
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of GLT8D1 mRNA"23195993
C547126AZM551248AZM551248 results in increased expression of GLT8D1 mRNA22323515
C030935benz(a)anthracenebenz(a)anthracene results in decreased expression of GLT8D1 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GLT8D1 mRNA26238291
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GLT8D1 mRNA22228805
C006780bisphenol Abisphenol A affects the expression of GLT8D1 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of GLT8D1 mRNA21786754
D002110CaffeineCaffeine results in decreased expression of GLT8D1 mRNA11793227
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of GLT8D1 mRNA23650126
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GLT8D1 gene20938992
D019327Copper SulfateCopper Sulfate results in decreased expression of GLT8D1 mRNA19549813
D003345CorticosteroneCorticosterone results in decreased expression of GLT8D1 mRNA15755911
D016572CyclosporineCyclosporine results in decreased expression of GLT8D1 mRNA25562108
D016572CyclosporineCyclosporine results in increased expression of GLT8D1 mRNA27989131
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of GLT8D1 mRNA27392435
D002945CisplatinCisplatin results in increased expression of GLT8D1 mRNA27392435
C000944dicrotophosdicrotophos results in decreased expression of GLT8D1 mRNA28302478
D004121Dimethyl SulfoxideDimethyl Sulfoxide affects the expression of GLT8D1 mRNA24834073
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GLT8D1 mRNA22079256
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of GLT8D1 mRNA23649840
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GLT8D1 gene20938992
D005897GlafenineGlafenine results in increased expression of GLT8D1 mRNA24136188
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of GLT8D1 mRNA20044591
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GLT8D1 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of GLT8D1 mRNA27392435
C410337K 7174K 7174 results in decreased expression of GLT8D1 mRNA24086573
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GLT8D1 gene20938992
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GLT8D1 mRNA23458150
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of GLT8D1 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of GLT8D1 mRNA23649840
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of GLT8D1 mRNA25380136
D009532NickelNickel results in decreased expression of GLT8D1 mRNA23195993
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of GLT8D1 mRNA23602845
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of GLT8D1 protein26879310
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of GLT8D1 mRNA17097637
D010634PhenobarbitalPhenobarbital affects the expression of GLT8D1 mRNA19159669
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GLT8D1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of GLT8D1 mRNA22079256
D011794QuercetinQuercetin results in decreased expression of GLT8D1 mRNA21632981
D012834SilverSilver results in decreased expression of GLT8D1 mRNA26014281
D012969Sodium FluorideSodium Fluoride results in decreased expression of GLT8D1 protein28918527
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GLT8D1 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GLT8D1 mRNA19465110
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GLT8D1 mRNA25613284
D013853ThioacetamideThioacetamide results in decreased expression of GLT8D1 mRNA11793227
D013853ThioacetamideThioacetamide results in increased expression of GLT8D1 mRNA23411599
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of GLT8D1 mRNA28065790
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of GLT8D1 mRNA"26179874
D014415TunicamycinTunicamycin results in increased expression of GLT8D1 mRNA17127020
D014520UrethaneUrethane results in decreased expression of GLT8D1 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of GLT8D1 mRNA25979313
D024483Vitamin K 3Vitamin K 3 affects the expression of GLT8D1 mRNA20044591

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0016757transferase activity, transferring glycosyl groups-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005794Golgi apparatus-IBA21873635  
GO:0016020membrane-HDA19946888  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal