Gene: UBAP2

55833
UBAP-2
ubiquitin associated protein 2
protein-coding
9p13.3
Ensembl:ENSG00000137073 Vega:OTTHUMG00000000427 UniprotKB:Q5T6F2
NC_000009.12
PubMed
0   ANCO-SNPs
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.649e-1 (AD)  5.730e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CHD80.905
VPS520.905
HERC20.902
LDB10.898
GBF10.895
GON4L0.895
VPS390.894
EP4000.894
UBR40.892
ATXN20.889

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.555
OR4F29-0.544
MTRNR2L6-0.369
KLRC2-0.365
MTRNR2L9-0.345
ODAM-0.341
CD8B-0.323
MTRNR2L10-0.319
AGTR1-0.315
TFPI2-0.312

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of UBAP2 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of UBAP2 mRNA"21346803
D000082AcetaminophenAcetaminophen results in increased expression of UBAP2 mRNA21420995|2223033
D000082AcetaminophenAcetaminophen affects the expression of UBAP2 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of UBAP2 gene27153756
D001280AtrazineAtrazine results in decreased expression of UBAP2 mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of UBAP2 mRNA22228805
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of UBAP2 mRNA"19150397
C006780bisphenol Abisphenol A results in decreased methylation of UBAP2 gene28582417
C006780bisphenol Abisphenol A results in increased expression of UBAP2 mRNA25181051
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of UBAP2 mRNA14729362
D019256Cadmium ChlorideCadmium Chloride results in increased expression of UBAP2 mRNA26472689
C018021cobaltous chloridecobaltous chloride affects the expression of UBAP2 mRNA alternative form19320972
C018021cobaltous chloridecobaltous chloride results in decreased expression of UBAP2 mRNA19320972
C000944dicrotophosdicrotophos results in increased expression of UBAP2 mRNA28302478
D004041Dietary FatsDietary Fats results in decreased expression of UBAP2 mRNA25016146
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of UBAP2 protein23301498
D000431EthanolEthanol results in decreased expression of UBAP2 mRNA29018328
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBAP2 mRNA17942748
C010974glyphosateglyphosate results in increased expression of UBAP2 mRNA25636363
D017313FenretinideFenretinide results in decreased expression of UBAP2 mRNA28973697
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of UBAP2 mRNA25613284
D007649KetamineKetamine results in decreased expression of UBAP2 mRNA20080153
D007854LeadLead results in decreased expression of UBAP2 mRNA19921347
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of UBAP2 mRNA23649840
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of UBAP2 protein26558463
D010795Phthalic AcidsPhthalic Acids results in increased expression of UBAP2 mRNA21061450
C006253pirinixic acidpirinixic acid results in increased expression of UBAP2 mRNA18301758
D011748PyrogallolPyrogallol results in increased expression of UBAP2 mRNA20362636
D011794QuercetinQuercetin results in increased expression of UBAP2 mRNA21632981
D012643SeleniumSelenium results in decreased expression of UBAP2 mRNA19244175
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of UBAP2 mRNA21570461|2468072
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBAP2 mRNA17942748
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of UBAP2 mRNA25613284
D014520UrethaneUrethane results in increased expression of UBAP2 mRNA28818685
D014635Valproic AcidValproic Acid results in increased expression of UBAP2 mRNA23179753
D014635Valproic AcidValproic Acid affects the expression of UBAP2 mRNA17963808
D001335Vehicle EmissionsVehicle Emissions affects the methylation of UBAP2 gene25560391
D014750VincristineVincristine results in decreased expression of UBAP2 mRNA23649840
D014810Vitamin EVitamin E results in decreased expression of UBAP2 mRNA19244175

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22658674  
GO:0045296cadherin binding-HDA25468996  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005737cytoplasm-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23739027Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence. (2013 Jul)Zuo LJ Stud Alcohol Drugs