Gene: SULF2

55959
HSULF-2
sulfatase 2
protein-coding
20q13.12
Ensembl:ENSG00000196562 MIM:610013 Vega:OTTHUMG00000032675 UniprotKB:Q8IWU5
NC_000020.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.701e-1 (AD)  7.571e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg18963059chr20:46376678SULF2Gene body7.157e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TNR0.761
MTSS10.731
SFPQ0.702
MARCKS0.695
HNRNPD0.675
FUS0.674
KIF1B0.672
QARS0.671
SRSF20.667
SLC35F10.666

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.621
OR4F29-0.601
LBP-0.253
ACOT6-0.232
FAM170B-0.206
RGR-0.196
FXYD3-0.184
ZNF705D-0.181
TMPRSS3-0.179
SPANXN1-0.178

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of SULF2 mRNA"26377693
C0122771,2-diamino-4-nitrobenzene"1,2-diamino-4-nitrobenzene affects the expression of SULF2 mRNA"17070881
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in decreased expression of SULF2 mRNA25596134
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of SULF2 mRNA"27413110
C0353141-nitropropane1-nitropropane results in increased expression of SULF2 mRNA17070881
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SULF2 mRNA"19167446
C0109142,4-diaminotoluene"2,4-diaminotoluene results in increased expression of SULF2 mRNA"17070881
C0252352,6-diaminotoluene"2,6-diaminotoluene results in increased expression of SULF2 mRNA"17070881
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of SULF2 mRNA"21346803
C0147062-nitro-4-phenylenediamine2-nitro-4-phenylenediamine results in decreased expression of SULF2 mRNA17070881
C0166172-nitropropane2-nitropropane results in increased expression of SULF2 mRNA17070881
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of SULF2 mRNA]"19467301
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
C0286764-acetylaminofluorene4-acetylaminofluorene results in decreased expression of SULF2 mRNA17070881
C5213345-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamate5-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamate affects the expression of SULF2 mRNA20932894
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of SULF2 mRNA22230336
C106812adefovir dipivoxiladefovir dipivoxil results in increased expression of SULF2 mRNA25596134
D016604Aflatoxin B1Aflatoxin B1 affects the expression of SULF2 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SULF2 mRNA21632981|2164198
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of SULF2 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SULF2 mRNA19770486
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SULF2 mRNA22484513
D000638AmiodaroneAmiodarone results in increased expression of SULF2 mRNA24535564
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of SULF2 mRNA24449571
C006632arsenic trioxidearsenic trioxide results in decreased expression of SULF2 mRNA22521957
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of SULF2 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SULF2 mRNA20106945|2163298
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SULF2 mRNA19770486|2261060
C038328BEP protocolBEP protocol results in increased expression of SULF2 mRNA18987330
D004958EstradiolEstradiol results in increased expression of SULF2 mRNA20106945|2163298
C044887beta-methylcholinebeta-methylcholine affects the expression of SULF2 mRNA21179406
C006780bisphenol Abisphenol A affects the expression of SULF2 mRNA23557687
C006780bisphenol Abisphenol A results in decreased expression of SULF2 mRNA25047013
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SULF2 mRNA28628672
C006780bisphenol Abisphenol A results in increased methylation of SULF2 promoter27312807
C006780bisphenol Abisphenol A affects the expression of SULF2 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of SULF2 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SULF2 mRNA28628672
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of SULF2 mRNA25596134
D002220CarbamazepineCarbamazepine affects the expression of SULF2 mRNA25979313
C004656chloroacetaldehydechloroacetaldehyde results in decreased expression of SULF2 mRNA25596134
D004390ChlorpyrifosChlorpyrifos results in increased expression of SULF2 mRNA21356183
D004390Chlorpyrifos[Copper co-treated with Chlorpyrifos] results in increased expression of SULF2 mRNA21356183
C059262cidofovircidofovir results in decreased expression of SULF2 mRNA25596134
D002922CiguatoxinsCiguatoxins affects the expression of SULF2 mRNA18353800
D004002Clodronic AcidClodronic Acid results in decreased expression of SULF2 mRNA25596134
D002994ClofibrateClofibrate results in increased expression of SULF2 mRNA17585979
C018021cobaltous chloridecobaltous chloride results in decreased expression of SULF2 mRNA19320972
C018021cobaltous chloridecobaltous chloride results in decreased expression of SULF2 mRNA24386269
D003300Copper[Copper co-treated with Chlorpyrifos] results in increased expression of SULF2 mRNA21356183
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of SULF2 mRNA20971185
D019327Copper SulfateCopper Sulfate results in decreased expression of SULF2 mRNA19549813
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SULF2 mRNA"19167446
D003375CoumestrolCoumestrol results in increased expression of SULF2 mRNA19167446
D003474CurcuminCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA]18200517
D016572CyclosporineCyclosporine results in decreased expression of SULF2 mRNA25562108|2559613
D016572CyclosporineCyclosporine results in decreased expression of SULF2 mRNA25596134
D000069439DasatinibDasatinib results in increased expression of SULF2 mRNA20579391
C014347decitabinedecitabine affects the expression of SULF2 mRNA23300844
D003703DemecolcineDemecolcine results in increased expression of SULF2 mRNA23649840
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SULF2 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SULF2 mRNA28628672
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of SULF2 mRNA21266533
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of SULF2 mRNA28962523
D002945CisplatinCisplatin affects the expression of SULF2 mRNA23300844
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of SULF2 mRNA27392435
D002945Cisplatin[Cisplatin co-treated with panobinostat] affects the expression of SULF2 mRNA21791302
D002945CisplatinCisplatin results in decreased expression of SULF2 mRNA25596134
D002945CisplatinCisplatin results in increased expression of SULF2 mRNA27392435
C000944dicrotophosdicrotophos results in increased expression of SULF2 mRNA28302478
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of SULF2 mRNA]"19467301
D004041Dietary FatsDietary Fats results in decreased expression of SULF2 mRNA18042831
D004041Dietary FatsDietary Fats results in increased expression of SULF2 mRNA19467301
C014476diethyl maleatediethyl maleate results in decreased expression of SULF2 mRNA21161181
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of SULF2 mRNA21607683
D002117CalcitriolCalcitriol results in increased expression of SULF2 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of SULF2 mRNA21592394
D0198131,2-Dimethylhydrazine"1,2-Dimethylhydrazine results in increased expression of SULF2 mRNA"27840820
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of SULF2 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of SULF2 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SULF2 mRNA17942748
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of SULF2 mRNA23649840
D011345FenofibrateFenofibrate results in decreased expression of SULF2 mRNA25596134
D011345FenofibrateFenofibrate results in decreased expression of SULF2 mRNA25596134
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of SULF2 mRNA21607683
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of SULF2 mRNA17070881
D005485FlutamideFlutamide results in increased expression of SULF2 mRNA21126777
D005485FlutamideFlutamide results in decreased expression of SULF2 mRNA24136188
D005557FormaldehydeFormaldehyde results in decreased expression of SULF2 mRNA28937961
D005557FormaldehydeFormaldehyde results in increased expression of SULF2 mRNA23649840
C039281furanfuran results in increased expression of SULF2 mRNA26194646
D019833GenisteinGenistein results in increased expression of SULF2 mRNA18847459
D017313FenretinideFenretinide results in decreased expression of SULF2 mRNA28973697
D007052IbuprofenIbuprofen results in decreased expression of SULF2 mRNA25596134
D007069IfosfamideIfosfamide results in decreased expression of SULF2 mRNA25596134
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SULF2 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SULF2 mRNA28628672
D007501IronIron deficiency results in increased expression of SULF2 mRNA20368581
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SULF2 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SULF2 mRNA28628672
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of SULF2 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of SULF2 mRNA23086925|2343069
D008154LucanthoneLucanthone results in increased expression of SULF2 mRNA21148553
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SULF2 mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of SULF2 mRNA26378955
C042720mercuric bromidemercuric bromide results in increased expression of SULF2 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
D008687MetforminMetformin results in decreased expression of SULF2 mRNA25596134
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of SULF2 mRNA23179753|2627250
C004925methylmercuric chloride"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SULF2 mRNA23649840
D008777MethyltestosteroneMethyltestosterone results in decreased expression of SULF2 mRNA29191790
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of SULF2 mRNA"29244179
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SULF2 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of SULF2 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SULF2 mRNA"25620056
C051752nefazodonenefazodone results in decreased expression of SULF2 mRNA24136188
C029938nickel sulfatenickel sulfate results in decreased expression of SULF2 mRNA22714537
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of SULF2 mRNA20971185
D010098OxycodoneOxycodone results in increased expression of SULF2 mRNA23439660
D010100OxygenOxygen deficiency results in decreased expression of SULF2 mRNA25596134
D010100Oxygen[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SULF2 mRNA25922074
D010100OxygenSULT1E1 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SULF2 mRNA]25922074
D000073878Palm OilPalm Oil results in decreased expression of SULF2 mRNA18042831
C496932panobinostat[Cisplatin co-treated with panobinostat] affects the expression of SULF2 mRNA21791302
C046012pentanalpentanal results in increased expression of SULF2 mRNA26079696
D010634PhenobarbitalPhenobarbital affects the expression of SULF2 mRNA19159669
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULF2 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of SULF2 mRNA26272509
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SULF2 mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of SULF2 mRNA17426115|1830175
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of SULF2 mRNA22714537
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of SULF2 mRNA27413110|2890350
D011374ProgesteroneProgesterone results in decreased expression of SULF2 mRNA23012394|2301818
D011374ProgesteroneProgesterone results in increased expression of SULF2 mRNA20864642
D011374ProgesteroneProgesterone results in increased expression of SULF2 mRNA19690047
C005556propionaldehydepropionaldehyde results in increased expression of SULF2 mRNA26079696
D011794QuercetinQuercetin results in increased expression of SULF2 mRNA21632981
C502851quinocetonequinocetone results in increased expression of SULF2 mRNA27046791
C059514resveratrolresveratrol results in increased expression of SULF2 mRNA25888808
C089730rosiglitazonerosiglitazone results in decreased expression of SULF2 mRNA25596134
C089730rosiglitazonerosiglitazone results in decreased expression of SULF2 mRNA25596134
D012715Sesame OilSesame Oil results in increased expression of SULF2 mRNA29191790
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of SULF2 mRNA25895662
D012906SmokeSmoke results in decreased expression of SULF2 mRNA21095227
C017947sodium arsenitesodium arsenite results in decreased expression of SULF2 mRNA20371982
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SULF2 mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of SULF2 mRNA26378955
C016766sulforafansulforafan results in increased expression of SULF2 mRNA26833863
D013629TamoxifenTamoxifen affects the expression of SULF2 mRNA17555576
D013629TamoxifenTamoxifen results in increased expression of SULF2 mRNA25123088
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of SULF2 mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of SULF2 mRNA21592394
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SULF2 mRNA28213091
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SULF2 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SULF2 gene]28213091
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SULF2 mRNA26290441
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SULF2 mRNA21215274
C009495titanium dioxidetitanium dioxide results in decreased expression of SULF2 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of SULF2 mRNA28065790
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of SULF2 mRNA24096154
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of SULF2 mRNA28111298
D014212TretinoinTretinoin results in decreased expression of SULF2 mRNA23724009
D014212TretinoinTretinoin results in increased expression of SULF2 mRNA21934132
D014212TretinoinTretinoin results in increased expression of SULF2 mRNA20488242
D014302Trinitrobenzenesulfonic AcidCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA]18200517
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA18200517
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of SULF2 mRNA29024780
C057693troglitazonetroglitazone results in increased expression of SULF2 mRNA28973697
C057693troglitazonetroglitazone results in decreased expression of SULF2 mRNA25596134
D014635Valproic AcidValproic Acid affects the expression of SULF2 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of SULF2 mRNA23179753|2718838
D014635Valproic AcidValproic Acid affects the expression of SULF2 mRNA17963808
D014635Valproic AcidValproic Acid results in increased expression of SULF2 mRNA24535564
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SULF2 gene25560391
C029297vinylidene chloridevinylidene chloride results in increased expression of SULF2 mRNA26682919
D014807Vitamin DVitamin D affects the expression of SULF2 mRNA20368581
C088658zoledronic acidzoledronic acid results in increased expression of SULF2 mRNA25596134

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004065arylsulfatase activity-IDA12368295  
GO:0004065arylsulfatase activity-IMP19520866  
GO:0005509calcium ion binding-IEA-  
GO:0008449N-acetylglucosamine-6-sulfatase activity-IDA18687675  
GO:0008449N-acetylglucosamine-6-sulfatase activity-IMP19520866  
GO ID GO Term Qualifier Evidence PubMed
GO:0001822kidney development-ISS-  
GO:0002063chondrocyte development-ISS-  
GO:0003094glomerular filtration-ISS-  
GO:0009611response to wounding-IEA-  
GO:0010575positive regulation of vascular endothelial growth factor production-ISS-  
GO:0014846esophagus smooth muscle contraction-ISS-  
GO:0030177positive regulation of Wnt signaling pathway-IDA19520866  
GO:0030201heparan sulfate proteoglycan metabolic process-IDA18687675  
GO:0030201heparan sulfate proteoglycan metabolic process-NAS12368295  
GO:0032836glomerular basement membrane development-ISS-  
GO:0035860glial cell-derived neurotrophic factor receptor signaling pathway-ISS-  
GO:0040037negative regulation of fibroblast growth factor receptor signaling pathway-ISS-  
GO:0048706embryonic skeletal system development-ISS-  
GO:0051216cartilage development-ISS-  
GO:0060348bone development-ISS-  
GO:0060384innervation-ISS-  
GO:0090263positive regulation of canonical Wnt signaling pathway-IEA-  
GO:0097421liver regeneration-IEA-  
GO:2000345regulation of hepatocyte proliferation-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005615extracellular space-NAS12368295  
GO:0005783endoplasmic reticulum-IDA18687675  
GO:0005795Golgi stack-IEA-  
GO:0005886plasma membrane-ISS-  
GO:0009986cell surface-IDA12368295  18687675  19520866  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27223083Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck. (2016 Jul 12)Flowers SAOncotarget