Gene: MAPK8

5599
JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c
mitogen-activated protein kinase 8
protein-coding
10q11.22
Ensembl:ENSG00000107643 MIM:601158 Vega:OTTHUMG00000018172 UniprotKB:P45983
NG_029053.2
PubMed
0   ANCO-SNPs
ND
6   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.286e-1 (AD)  9.112e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg05241265chr10:49614052MAPK8Gene body2.076e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ATP6V1C10.971
CHIC10.968
MAP2K40.967
GSK3B0.967
GLS0.965
SCN2A0.964
ATP6V1A0.964
TRIM370.963
RNMT0.962
GABRA10.961

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CSAG1-0.493
OR4F5-0.478
HEY2-0.476
MYL3-0.467
RHOD-0.464
RAB13-0.456
SYDE1-0.448
RNF135-0.444
RAI14-0.443
ROM1-0.441

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB017822,6-Dihydroanthra/1,9-Cd/Pyrazol-6-OneSmall MoleculeExperimentalTarget
DB072186-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONESmall MoleculeExperimentalTarget
DB072682-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDESmall MoleculeExperimentalTarget
DB07272N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDESmall MoleculeExperimentalTarget
DB072765-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDESmall MoleculeExperimentalTarget
DB078452-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamideSmall MoleculeExperimentalTarget
ID Drug Name Action PubMed
C496879103D5R103D5R results in decreased phosphorylation of MAPK8 protein15695405
C4350441-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]"19927300
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21544200
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [evodiamine results in increased expression of MAPK8 protein modified form]"23774672
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]"19927300
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21544200
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]"19887573
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]"15254339
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21544200
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]"11981161
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]"10696784
C0334891,3-dichloro-2-propanol"1,3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein"26143167
C0374131,3-dinitropyrene"1,3-dinitropyrene results in increased phosphorylation of MAPK8 protein"17240030
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]"19927300
C0152621,6-hexamethylene diisocyanate"1,6-hexamethylene diisocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]"27129696
C0152621,6-hexamethylene diisocyanate"1,6-hexamethylene diisocyanate results in increased phosphorylation of MAPK8 protein"27129696
C0501751-hydroxy-2-naphthoic acid"1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]"21667204
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased phosphorylation of MAPK8 protein"19768117
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"MAP3K5 protein affects the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased phosphorylation of MAPK8 protein]"19768117
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"MAPK8 protein affects the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased degradation of MCL1 protein]"19768117
C0326681-nitropyrene1-nitropyrene results in increased phosphorylation of MAPK8 protein17240030
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MAPK8 mRNA"22543052
C5112952,2',4,4'-tetrabromodiphenyl ether"ERN1 protein affects the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MAPK8 mRNA]"22543052
C4172072,2',4,6,6'-pentachlorobiphenyl"2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of MAPK8 protein"16778083
C4172072,2',4,6,6'-pentachlorobiphenyl"PD168393 inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of MAPK8 protein]"16778083
C4172072,2',4,6,6'-pentachlorobiphenyl"WHI P154 inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of MAPK8 protein]"16778083
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]15531749
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein]20829427
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]11981161
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]]"27274199
C5054562-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]15951400
C5054562-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one results in increased phosphorylation of MAPK8 protein15951400
C0700552,3',4,4',5-pentachlorobiphenyl"MAPK8 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]"26519956
C0700552,3',4,4',5-pentachlorobiphenyl"MAPK8 affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]"26519956
C0787652,3,5-(triglutathion-S-yl)hydroquinone"2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein"21135414
C0787652,3,5-(triglutathion-S-yl)hydroquinone"Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21135414
C0787652,3,5-(triglutathion-S-yl)hydroquinone"Reactive Oxygen Species affects the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21135414
C0787652,3,5-(triglutathion-S-yl)hydroquinone"[[CAT protein co-treated with Polyethylene Glycols] inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased abundance of Reactive Oxygen Species]] inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21135414
C0359762,4,2',4'-tetrachlorobiphenyl"2,4,2',4'-tetrachlorobiphenyl results in increased phosphorylation of MAPK8 protein"12711418
C4408502,4,3',5'-tetramethoxystilbene"2,4,3',5'-tetramethoxystilbene results in increased phosphorylation of MAPK8 protein"20490654
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of MAPK8 protein"12711418
C4257842-(4-amino-3-methylphenyl)-5-fluorobenzothiazole2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased phosphorylation of MAPK8 protein25781201
C5431502-(4-((dimethylamino)methyl)benzylidene)-5,6-dimethoxy-2,3-dihydroinden-1-one"2-(4-((dimethylamino)methyl)benzylidene)-5,6-dimethoxy-2,3-dihydroinden-1-one inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MAPK8 protein]"19345205
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Pt(O,O'-acac)(gamma-acac)(DMS) results in increased phosphorylation of MAPK8 protein]"21420390
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]11306679
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of and results in increased activity of MAPK8 protein16018989
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of MAPK8 protein16442704
C4882882,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid"[Cisplatin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of MAPK8 protein"21214929
C4882882,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid"[Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of MAPK8 protein"21214929
C0149702-aminodiphenyl2-aminodiphenyl results in increased phosphorylation of MAPK8 protein23836369
C0149702-aminodiphenylAcetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK8 protein]23836369
C4843272'-benzoyloxycinnamaldehyde"2'-benzoyloxycinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"20933287
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased phosphorylation of MAPK8 protein18675330
C0879392''-galloylhyperin2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]28213291
C0546493-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol"3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein"18950629
C0546493-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol"rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]"18950629
C0546493-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol"wortmannin inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]"18950629
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]"19631264
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile[3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with entinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein15964800
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile[3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein15964800
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased activity of MAPK8 protein11051267
C4902573-O-caffeoyl-1-methylquinic acid3-O-caffeoyl-1-methylquinic acid results in increased phosphorylation of MAPK8 protein16631525
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of MAPK8 mRNA"18648102
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein]10910949
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA"27188386
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine analog inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK8 protein]"12902192
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Anisomycin results in increased phosphorylation of MAPK8 protein]"15772366
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]"15772366
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK8 protein]"15772366
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione results in increased phosphorylation of MAPK8 protein"24824809
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased activity of MAPK8 protein11488593
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein12684028
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein24825450
C0275764-hydroxy-2-nonenalHydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]12684028
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased activity of MAPK8 protein17263905
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein16322078
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein15064094
C0275764-hydroxy-2-nonenalGSTA4 protein inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein]15064094
C0275764-hydroxy-2-nonenalMAPK8 protein affects the susceptibility to 4-hydroxy-2-nonenal17263905
C0275764-hydroxy-2-nonenalresveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]16322078
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK8 protein]16401635
C0415944-nonylphenol4-nonylphenol analog results in increased phosphorylation of MAPK8 protein27086933
C0757734-phenylbutyric acid4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein]21147958
C0297284-phenylenediamine4-phenylenediamine results in increased phosphorylation of MAPK8 protein23172806
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide results in increased expression of MAPK8 mRNA20829426
C5036435-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin"MAPK8 protein promotes the reaction [5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin affects the expression of CDC25C protein]"16179969
C5036435-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin"MAPK8 protein promotes the reaction [5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin results in increased phosphorylation of HIST3H3 protein]"16179969
C5031195-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK8 protein15831436
C5031195-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolonepyrazolanthrone inhibits the reaction [5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK8 protein]15831436
C4035635-7-oxo-zeaenol5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]22171160
C4035635-7-oxo-zeaenol5-7-oxo-zeaenol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]22171160
C439285(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride results in increased activity of MAPK8 protein11051267
C439285(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride"8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride results in increased activity of MAPK8 protein]"11051267
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol results in decreased expression of MAPK8 protein modified form]"27093858
C1062506,7-dimethoxy-3-phenylquinoxaline"6,7-dimethoxy-3-phenylquinoxaline inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]"26385185
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]"20206247
C0548527-hydroxystaurosporine[7-hydroxystaurosporine co-treated with Sirolimus] results in increased phosphorylation of MAPK8 protein15767555
C0548527-hydroxystaurosporinepyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased phosphorylation of MAPK8 protein]15767555
C0908608-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate"8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride results in increased activity of MAPK8 protein]"11051267
C5528608-bromo-7-methoxychrysin8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein20632440
C5528608-bromo-7-methoxychrysinAcetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein]20632440
C5528608-bromo-7-methoxychrysinpyrazolanthrone inhibits the reaction [8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein]20632440
D000079AcetaldehydeAcetaldehyde results in increased phosphorylation of MAPK8 protein19110045
D000079AcetaldehydeHesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein]19110045
D000079AcetaldehydeAcetaldehyde results in increased activity of MAPK8 protein10733585
D000082AcetaminophenAcetaminophen results in decreased expression of MAPK8 mRNA27761495
D000082AcetaminophenAcetaminophen results in increased expression of MAPK8 mRNA20732408|2776149
D000082AcetaminophenAcetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein17185352
D000082AcetaminophenAcetaminophen results in increased activity of and affects the localization of MAPK8 protein22980195
D000082AcetaminophenAcetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein19436114
D000082AcetaminophenAcetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein17185352
D000082AcetaminophenAcetaminophen results in increased phosphorylation of and affects the localization of MAPK8 protein25752611|2700250
D000082AcetaminophenAcetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein18700144|1973926
D000082AcetaminophenAcetaminophen results in increased phosphorylation of MAPK8 protein19931551|2036382
D000082AcetaminophenGlutathione inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]20423716
D000082AcetaminophenIL4 gene mutant form promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]22107450
D000082Acetaminophenmanumycin inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein]19739265
D000082AcetaminophenMAP3K5 protein promotes the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein]18700144
D000082AcetaminophenMAPK8 protein results in increased susceptibility to Acetaminophen18700144
D000082AcetaminophenOGT gene mutant form inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein]29325178
D000082AcetaminophenPARK2 gene mutant form affects the reaction [Acetaminophen results in increased phosphorylation of and affects the localization of MAPK8 protein]25752611
D000082AcetaminophenPARK2 mutant form affects the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]25752611
D000082Acetaminophenpyrazolanthrone affects the reaction [TALDO1 gene mutant form promotes the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]]19436114
D000082Acetaminophenpyrazolanthrone inhibits the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]19436114
D000082Acetaminophenpyrazolanthrone inhibits the reaction [Acetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein]17185352
D000082Acetaminophenresveratrol inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]25956474
D000082AcetaminophenTALDO1 gene mutant form promotes the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]19436114
D000082Acetaminophenthiamet G promotes the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein]29325178
D000082Acetaminophenzinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]20423716
D000082AcetaminophenAcetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein11562448
D000082AcetaminophenMAP2K4 mutant form inhibits the reaction [Acetaminophen results in increased activity of MAPK8 protein]11562448
D000082AcetaminophenMAPK8 results in increased susceptibility to Acetaminophen11562448
D000082AcetaminophenAcetaminophen results in increased expression of MAPK8 protein modified form20166895
C056165acetovanilloneacetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
C056165acetovanilloneacetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
C056165acetovanilloneacetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]24967690
C056165acetovanilloneacetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]20354174
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23816505
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]23816505
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21135414
D000111AcetylcysteineAcetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK8 protein]23836369
D000111AcetylcysteineAcetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein]20632440
D000111AcetylcysteineAcetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK8 protein]12684028
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]18412143
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein]"24735948
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK8 protein]15173093
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Bortezomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein]15173093
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK8 protein]28600122
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK8 protein]"28087840
D000111AcetylcysteineAcetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK8 protein]12902192
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]24386346
D000111AcetylcysteineAcetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]21958719
D000111AcetylcysteineAcetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]21958719
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D000111AcetylcysteineAcetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein]28801140
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]18728404
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Spermine results in increased activity of MAPK8 protein]20121705
D000111AcetylcysteineAcetylcysteine results in decreased phosphorylation of MAPK8 protein24735948
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]25531190
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein]14687664
D000111AcetylcysteineAcetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK8 protein]19654923
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein]17481858
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]10397638
D000111AcetylcysteineAcetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]11306679
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]21145380
D000111AcetylcysteineAcetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein]19760616
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]22767315
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]22085843
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein]17041759
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]17383151
C063261acetylleucyl-leucyl-norleucinalacetylleucyl-leucyl-norleucinal results in increased phosphorylation of MAPK8 protein15618349
C074400aciculatinaciculatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21548916
D000171AcroleinAcrolein results in increased phosphorylation of MAPK8 protein11329622|1553174
D000171AcroleinPhenylbutyrates inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein]18951912
D000171Acroleintyrphostin AG 1478 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein]11329622
D000171AcroleinAcrolein results in increased phosphorylation of MAPK8 protein12487375
D000171Acrolein[Acrolein results in increased phosphorylation of MAPK8 protein] which results in increased phosphorylation of JUN protein12487375
D000171AcroleinSB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein]12487375
D020106AcrylamideAcetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]25531190
D020106AcrylamideAcrylamide results in increased phosphorylation of MAPK8 protein25531190
D020106Acrylamidepyrazolanthrone inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]25531190
D000244Adenosine DiphosphateDicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein]24466103
C016601afimoxifeneMAPK8 results in decreased susceptibility to afimoxifene21233418
C412373AG 1879AG 1879 inhibits the reaction [MIF protein results in increased phosphorylation of MAPK8 protein]16872482
C412373AG 1879"AG 1879 inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK8 protein]"21501596
C412373AG 1879AG 1879 inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]20354174
C412373AG 1879AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]15772366
C412373AG 1879AG 1879 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
D000393Air PollutantsAir Pollutants affects the expression of MAPK8 mRNA24351557
C038491allyl sulfideallyl sulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein17647244
C011860alpha-chaconine"alpha-chaconine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"25913072
D024502alpha-Tocopherolalpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein20686688
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein]12684028
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein]14645110
D024502alpha-Tocopherolbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein]20686688
D024502alpha-Tocopherolsalubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein]20686688
D024502alpha-Tocopherol[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK8 protein]16401635
C010845aluminum chloridealuminum chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein12865155
C010845aluminum chlorideCEP-11004 inhibits the reaction [aluminum chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]12865155
C077990alvocidib[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK8 protein15634644
C077990alvocidibalvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein]15039284
D000584AmilorideAmiloride inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein]19815690
D000596Amino AcidsAmino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein]25309793
D000596Amino AcidsH 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein]]25309793
D006710Homocysteinefulvic acid inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK8 protein]25888188
D006710HomocysteineHomocysteine results in increased phosphorylation of MAPK8 protein25888188
D000643Ammonium ChlorideAmmonium Chloride affects the expression of MAPK8 mRNA16483693
D000661AmphetamineMAPK8 protein promotes the reaction [Amphetamine results in increased expression of GJA1 protein]15194466
C006578anetholeanethole inhibits the reaction [TNF protein results in increased activity of MAPK8 protein]10871845
C023650anilineaniline results in increased phosphorylation of MAPK8 protein16169568|1842024
D000841AnisomycinAnisomycin results in increased activity of MAPK8 protein12902192
D000841AnisomycinAnisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein15737997|1824184
D000841AnisomycinAnisomycin results in increased phosphorylation of MAPK8 protein12967334
D000841AnisomycinMAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]15737997
D000841Anisomycinquinoline analog inhibits the reaction [MAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]]15737997
D000841Anisomycin"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Anisomycin results in increased phosphorylation of MAPK8 protein]"15772366
D000841AnisomycinAnisomycin results in increased phosphorylation of MAPK8 protein15772366|1603879
D000841AnisomycinAnisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein15961565
D000880AnthraquinonesAnthraquinones analog results in increased phosphorylation of MAPK8 protein19686834
C037554antimony trioxide[antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein16112521
C037554antimony trioxideantimony trioxide results in increased activity of MAPK8 protein16112521
C037554antimony trioxideButhionine Sulfoximine promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]16112521
C037554antimony trioxideGlutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]16112521
C037554antimony trioxideMAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein]16112521
C117813apicularen Aapicularen A results in increased phosphorylation of and results in increased expression of MAPK8 protein15561798
D047310ApigeninApigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]25557508
D016718Arachidonic AcidMAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]19540902
D016718Arachidonic AcidMAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]19540902
D016718Arachidonic AcidMAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]19540902
D001104ArbutinArbutin results in decreased expression of MAPK8 mRNA17103032
D001149Arsenates[Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK8 protein19895865
D001149Arsenates[Arsenates co-treated with chromium hexavalent ion] results in increased phosphorylation of MAPK8 protein19895865
D001151ArsenicArsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein14633691
D001151ArsenicArsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein11756236
D001151ArsenicArsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein15210857
D001151Arsenic"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein]"15210857
D001151Arsenic"O(2)-(2,4-dinitrophenyl) 1-(4-(N,N-diethylcarboxamido)piperazin-1-yl)diazen-1-ium 1,2-diolate promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein]"15210857
D001151ArsenicRo 31-8220 inhibits the reaction [Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein]11756236
D001152ArsenicalsMAPK8 mutant form affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein]23255093
D001152ArsenicalsMAPK8 mutant form inhibits the reaction [Arsenicals results in increased phosphorylation of AKT1 protein]23255093
D001152ArsenicalsMAPK8 mutant form inhibits the reaction [Arsenicals results in increased phosphorylation of EZH2 protein]23255093
C050510arsenic trichloridearsenic trichloride results in increased phosphorylation of MAPK8 protein22696236|2443465
C050510arsenic trichloridepyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK8 protein]22696236
C050510arsenic trichlorideMAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein]22696236
C050510arsenic trichlorideMAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein]22696236
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]18412143
C006632arsenic trioxidearsenic trioxide promotes the reaction [puerarin results in increased expression of MAPK8 protein]20416161
C006632arsenic trioxidearsenic trioxide results in increased activity of MAPK8 protein11304686|1229699
C006632arsenic trioxidearsenic trioxide results in increased expression of MAPK8 protein17374990
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein14610070|1596127
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of MAPK8 protein18412143|2053473
C006632arsenic trioxideButhionine Sulfoximine promotes the reaction [arsenic trioxide results in increased activity of MAPK8 protein]14701702
C006632arsenic trioxideDicumarol inhibits the reaction [arsenic trioxide results in increased activity of MAPK8 protein]14701702
C006632arsenic trioxide[IL24 protein co-treated with arsenic trioxide] results in increased phosphorylation of MAPK8 protein15580305
C006632arsenic trioxideindole-5-carboxamide promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]16818652
C006632arsenic trioxideMAP2K4 gene mutant form inhibits the reaction [arsenic trioxide results in increased activity of MAPK8 protein]14701702
C006632arsenic trioxideMAPK8 affects the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]18281123
C006632arsenic trioxideMAPK8 mutant form inhibits the reaction [arsenic trioxide results in increased activity of CASP3 protein]20799280
C006632arsenic trioxideMAPK8 mutant form inhibits the reaction [arsenic trioxide results in increased phosphorylation of BCL2 protein]18412143
C006632arsenic trioxideMAPK8 mutant form inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK1 protein]20799280
C006632arsenic trioxideMAPK8 mutant form inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK3 protein]20799280
C006632arsenic trioxideMAPK8 mutant form inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK9 protein]20799280
C006632arsenic trioxideMAPK8 protein affects the reaction [arsenic trioxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein]20534739
C006632arsenic trioxideMAPK8 protein affects the reaction [arsenic trioxide results in increased activity of CASP3 protein]20534739
C006632arsenic trioxideMAPK8 protein affects the reaction [arsenic trioxide results in increased activity of CASP8 protein]20534739
C006632arsenic trioxideMAPK8 protein affects the reaction [arsenic trioxide results in increased activity of CASP9 protein]20534739
C006632arsenic trioxideMAPK8 protein affects the reaction [arsenic trioxide results in increased expression of PTEN protein]20534739
C006632arsenic trioxideMAPK8 protein affects the susceptibility to arsenic trioxide16818652
C006632arsenic trioxideMAPK8 results in increased susceptibility to arsenic trioxide20799280
C006632arsenic trioxideMAPK9 mutant form inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]20799280
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]18412143|2053473
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]14610070
C006632arsenic trioxideSB 203580 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]16818652
C006632arsenic trioxideSCIO-469 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]16818652
C006632arsenic trioxideTetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]14610070
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of MAPK8 protein15688020
C006632arsenic trioxideMAPK8 protein results in increased susceptibility to arsenic trioxide16818652
C006632arsenic trioxideMAPK8 results in increased susceptibility to arsenic trioxide16818652
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]21145380
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of MAPK8 protein21145380|2717476
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]27174766
C015001arsenitearsenite results in decreased expression of MAPK8 mRNA18191166
C015001arsenitearsenite results in increased phosphorylation of and results in increased activity of MAPK8 protein15014438
C015001arsenitearsenite results in increased phosphorylation of MAPK8 protein19808956
C015001arseniteMAP3K8 protein affects the reaction [arsenite results in increased phosphorylation of MAPK8 protein]19808956
C015001arsenitearsenite affects the reaction [DUSP8 protein binds to MAPK8 protein]23159405
D001194AsbestosAsbestos results in increased phosphorylation of and results in increased activity of MAPK8 protein11280724
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of MAPK8 mRNA"25757056
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of MAPK8 mRNA"19446018
D001205Ascorbic Acid[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein24488945
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]20206247
D001205Ascorbic AcidCAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein]24488945
D001205Ascorbic Acid[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK8 protein]16401635
C022870asoxime chloride[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein]21971501
C108637aspartyl-glutamyl-valyl-aspartalaspartyl-glutamyl-valyl-aspartal inhibits the reaction [Paclitaxel results in increased activity of MAPK8 protein]11160861
D001280AtrazineAtrazine results in increased expression of MAPK8 mRNA22378314
D001285Atropine[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein]21971501
C406592azaspiracid"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein]"19815690
C406592azaspiracidAmiloride inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein]19815690
C406592azaspiracidazaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein19815690
C006680baicaleinbaicalein results in decreased phosphorylation of and results in decreased activity of MAPK8 protein10718847
C012765bakuchiolbakuchiol results in increased phosphorylation of MAPK8 protein27033605
C012765bakuchiolbakuchiol results in increased phosphorylation of and results in increased activity of MAPK8 protein17292878
C028559bathocuproine sulfonatebathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein]18056745
C028559bathocuproine sulfonatebathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]11239917
C028559bathocuproine sulfonatebathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein]10941151
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of MAPK8 protein"15698582|2205391
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in increased phosphorylation of MAPK8 protein15698582
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of MAPK8 protein16041517
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of MAPK8 protein15698582
D001564Benzo(a)pyreneNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein]16041517
D001564Benzo(a)pyrenepyrazolanthrone inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein]16041517
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of MAPK8 protein18321868
D001564Benzo(a)pyreneCurcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein]18321868
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK8 protein"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK8 protein"21501596
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"AG 1879 inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK8 protein]"21501596
C427308benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]15917298
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein]20686688
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeMAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]23593480
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeMAPK8 gene mutant form results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde23593480
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of MAPK8 protein18463101
D019207beta Carotene[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK8 protein]16401635
D004958EstradiolEstradiol results in decreased expression of MAPK8 mRNA16029874
D004958EstradiolEstradiol inhibits the reaction [Gentamicins results in increased activity of MAPK8 protein]20074632
C023888beta-hexachlorocyclohexaneAcetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein]19760616
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein19760616
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [puag-haad results in increased expression of MAPK8 mRNA]28780155
C070515bisindolylmaleimide Ibisindolylmaleimide I results in decreased expression of MAPK8 mRNA28780155
C006780bisphenol Abisphenol A results in decreased expression of MAPK8 mRNA29275510
C006780bisphenol Abisphenol A affects the expression of MAPK8 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of and results in increased phosphorylation of MAPK8 protein17322771
C006780bisphenol Abisphenol A results in increased phosphorylation of MAPK8 protein20096755
D001786Blood Glucose"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]]"27274199
D001786Blood Glucose[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein27274199
D001786Blood Glucoseursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]27274199
D000069286BortezomibAcetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK8 protein]15173093
D000069286BortezomibAcetylcysteine inhibits the reaction [[Bortezomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein]15173093
D000069286Bortezomibalvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein]15039284
D000069286Bortezomib[[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein15173093
D000069286Bortezomib[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK8 protein12893773|1517309
D000069286Bortezomib[Bortezomib co-treated with sorafenib] results in increased phosphorylation of MAPK8 protein16985072
D000069286Bortezomib[[Bortezomib co-treated with vorinostat] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein15173093
D000069286Bortezomib[Bortezomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein12893773|1517309
D000069286BortezomibBortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein15039284
D000069286BortezomibBortezomib results in increased phosphorylation of MAPK8 protein18559525
D000069286BortezomibCGC 11093 promotes the reaction [Bortezomib results in increased phosphorylation of MAPK8 protein]18559525
D000069286BortezomibMAPK8 results in increased susceptibility to [Bortezomib co-treated with CGC 11093]18559525
C439264bovine serum albumin-corticosterone conjugatebovine serum albumin-corticosterone conjugate results in increased phosphorylation of and results in increased activity of MAPK8 protein15961565
C022777bufalinbufalin results in decreased activity of MAPK8 protein21922632
D016642BupropionBupropion results in increased phosphorylation of and results in increased activity of MAPK8 protein21354251
D019328Buthionine Sulfoximine[antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein16112521
D019328Buthionine SulfoximineButhionine Sulfoximine promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]16112521
D019328Buthionine SulfoximineButhionine Sulfoximine promotes the reaction [arsenic trioxide results in increased activity of MAPK8 protein]14701702
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK8 protein]16407847
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]15989949
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]18691550
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]18691550
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]18593901
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]18593901
D020122tert-ButylhydroperoxideLY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein]28063877
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein28063877
D020122tert-Butylhydroperoxide[phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein20423716
C018475butyraldehydebutyraldehyde results in decreased expression of MAPK8 mRNA26079696
D002087ButyratesAcetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK8 protein]15173093
D002087Butyrates[[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein15173093
D002087Butyrates[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK8 protein12893773|1517309
D002087Butyrates[perifosine co-treated with Butyrates] results in increased activity of MAPK8 protein15781658
D020148Butyric AcidAcetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK8 protein]28600122
D020148Butyric AcidButyric Acid results in increased phosphorylation of MAPK8 protein28600122
D002101Cacodylic AcidCacodylic Acid results in increased expression of MAPK8 mRNA17441966
D002101Cacodylic AcidCacodylic Acid results in decreased expression of MAPK8 mRNA17481689
D002104Cadmiumacetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
D002104CadmiumAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
D002104CadmiumCadmium results in increased phosphorylation of MAPK8 protein26187450|2651492
D002104Cadmiumdiphenyleneiodonium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
D002104CadmiumMAPK8 mutant form results in decreased susceptibility to Cadmium10874022
D002104CadmiumSelenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26187450
D002104Cadmiumtyrphostin AG 1478 inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
D002104Cadmium"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]"15254339
D002104CadmiumCadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein16728380|1850679
D002104CadmiumCadmium results in increased phosphorylation of MAPK8 protein15212812|1525433
D002104CadmiumEgtazic Acid inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]15254339
D002104Cadmium[MT1 protein co-treated with MT2 protein] inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]16568437
D002104Cadmiumpyrazolanthrone inhibits the reaction [Cadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein]18506790
D002104CadmiumSilymarin inhibits the reaction [Cadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein]16728380
D002104CadmiumCadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein16568437
D002104CadmiumCadmium results in increased phosphorylation of MAPK8 protein18463101
D002104CadmiumMAPK8 protein affects the susceptibility to Cadmium16516943
C028031cadmium acetatecadmium acetate results in increased phosphorylation of MAPK8 protein15925026
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21544200
D019256Cadmium ChlorideCadmium Chloride results in increased expression of MAPK8 protein modified form24419708
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein21544200
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK8 protein10874044|1626426
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D019256Cadmium ChlorideMAPK8 protein promotes the reaction [Cadmium Chloride results in increased phosphorylation of JUN protein]25374377
D019256Cadmium ChlorideMAPK8 protein results in increased susceptibility to Cadmium Chloride25374377
D019256Cadmium Chloridepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21219922
D019256Cadmium Chloridesalubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21809093
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21544200
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]"19887573
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein15081267|1672838
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK8 protein11958953|1834825
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D019256Cadmium ChlorideLL Z1640-2 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]15081267
D019256Cadmium Chloride[MAP2K4 co-treated with MAP2K7] affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]18348256
D019256Cadmium ChlorideMAP2K4 mutant form inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]18348256
D019256Cadmium ChlorideMAP2K7 mutant form inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]18348256
D019256Cadmium ChlorideMAPK8 mutant form inhibits the reaction [Cadmium Chloride results in increased expression of HSPA1A protein]18348256
D019256Cadmium ChlorideMAPK8 protein promotes the reaction [Cadmium Chloride results in increased expression of GADD45A protein]19887573
D019256Cadmium ChlorideMT1 affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]11958953
D019256Cadmium ChlorideMT2 affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]11958953
D019256Cadmium ChlorideSilymarin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]16728380
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK8 protein17027146
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21544200
D019256Cadmium Chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein]20829427
D019256Cadmium Chloride[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein20829427
D019256Cadmium ChlorideCadmium Chloride results in increased activity of MAPK8 protein10637132
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein15618353|2154420
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK8 protein18021293|2193318
D019256Cadmium ChlorideCAMK2A mutant form inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21933187
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D019256Cadmium ChlorideKN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21933187
D019256Cadmium Chloride"N(6),N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"15618353
D019256Cadmium Chloridepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21933187
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]"10696784
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]17383151
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK8 protein10696784|1738315
D019256Cadmium ChlorideSelenium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]17383151
D019256Cadmium ChlorideXBP1 affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]18086661
D019256Cadmium ChlorideMAPK8 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D019256Cadmium ChlorideMAPK8 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D019256Cadmium ChlorideMAPK8 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]11709198
C058667cadmium selenide[cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK8 mRNA22342292
C037123cadmium sulfateAcetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein]14687664
C037123cadmium sulfatecadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein14687664
C037123cadmium sulfateAcetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]22767315
C037123cadmium sulfatecadmium sulfate results in increased phosphorylation of MAPK8 protein22767315
C037123cadmium sulfateGlutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]22767315
C472707caffeoylquinic acidcaffeoylquinic acid analog results in increased phosphorylation of MAPK8 protein19647727
D000001Calcimycinfulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA]21331654
D000001Calcimycin[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA21331654
C055085calcipotrieneMAPK8 gene mutant form results in decreased susceptibility to calcipotriene24046278
C081643candesartancandesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]20562518
D002211Capsaicin5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]22171160
D002211Capsaicin5-7-oxo-zeaenol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]22171160
D002211CapsaicinCapsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK8 protein]21462327
D002211CapsaicinCapsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]21745629
D002211CapsaicinCapsaicin results in increased activity of MAPK8 protein12478662|1729249
D002211Capsaicin[Capsaicin results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein17292493
D002211CapsaicinCapsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein22171160
D002211CapsaicinCapsaicin results in increased phosphorylation of MAPK8 protein20619260
D002211Capsaicincapsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]22171160
D002211CapsaicinDUSP1 mutant form promotes the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]22171160
D002211CapsaicinMAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]22171160
D002211CapsaicinMAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]22171160
D002211CapsaicinMAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]22171160
D002211CapsaicinMAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]17292493
D002211CapsaicinNFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]22171160
C071423capsazepinecapsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]22171160
D002220CarbamazepineCarbamazepine affects the expression of MAPK8 mRNA24752500
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased phosphorylation of MAPK8 protein21291945
D002251Carbon Tetrachlorideferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein]21291945
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased phosphorylation of MAPK8 protein17285312|1906685
C524865carfilzomib[carfilzomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein20233973
D000068579CelecoxibCelecoxib inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein]16442704
C469298CEP-11004CEP-11004 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]17698565
C469298CEP-11004CEP-11004 inhibits the reaction [aluminum chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]12865155
D002518CeramidesCeramides results in increased phosphorylation of and results in increased activity of MAPK8 protein20696185
C515676CGC 11093CGC 11093 promotes the reaction [Bortezomib results in increased phosphorylation of MAPK8 protein]18559525
C515676CGC 11093CGC 11093 results in increased phosphorylation of MAPK8 protein18559525
C515676CGC 11093MAPK8 results in increased susceptibility to [Bortezomib co-treated with CGC 11093]18559525
D002599ChalconeChalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]22155221
D002635Chenodeoxycholic AcidChenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]25496033
D002635Chenodeoxycholic AcidChenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]25496033
D002734Chlorophyll"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of MAPK8 mRNA]"22079312
D002737ChloropreneChloroprene results in increased expression of MAPK8 mRNA23125180
D002746Chlorpromazine[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein23238562
D002746Chlorpromazine"Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"23238562
D002746ChlorpromazineTIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]23238562
D002746Chlorpromazine"TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]]"23238562
D004390ChlorpyrifosChlorpyrifos results in increased phosphorylation of MAPK8 protein22714038
D020355CholatesCholates results in increased phosphorylation of MAPK8 protein15750181
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein23038002
D002794CholineTamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein]23038002
C529269cholix toxin, Vibrio cholerae"Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK8 protein]"28087840
C529269cholix toxin, Vibrio cholerae"cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK8 protein"28087840
C529269cholix toxin, Vibrio cholerae"Go 6976 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased phosphorylation of MAPK8 protein]"28087840
C529269cholix toxin, Vibrio cholerae"U 0126 inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK8 protein]"28087840
D002857ChromiumChromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]21134603
C074702chromium hexavalent ion"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine analog inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK8 protein]"12902192
C074702chromium hexavalent ionAcetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK8 protein]12902192
C074702chromium hexavalent ionBCAR1 protein affects the reaction [chromium hexavalent ion results in increased activity of MAPK8 protein]12902192
C074702chromium hexavalent ionchromium hexavalent ion results in increased activity of MAPK8 protein12902192
C074702chromium hexavalent ionchromium hexavalent ion results in increased phosphorylation of MAPK8 protein17045426
C074702chromium hexavalent ionAcetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK8 protein]19654923
C074702chromium hexavalent ion[Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK8 protein19895865
C074702chromium hexavalent ion[Arsenates co-treated with chromium hexavalent ion] results in increased phosphorylation of MAPK8 protein19895865
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of MAPK8 protein19895865
C074702chromium hexavalent ionchromium hexavalent ion results in increased phosphorylation of MAPK8 protein19654923|1989586
C074702chromium hexavalent ionMAP2K4 protein promotes the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK8 protein]19654923
C074702chromium hexavalent ionMAP2K7 protein promotes the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK8 protein]19654923
C012843cinnamic aldehydecinnamic aldehyde results in increased phosphorylation of and results in increased activity of MAPK8 protein15964311
C012843cinnamic aldehydecinnamic aldehyde results in increased phosphorylation of MAPK8 protein21469739
C012843cinnamic aldehydepyrazolanthrone inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK8 protein]15964311
C012843cinnamic aldehydeSB 203580 inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK8 protein]15964311
C012843cinnamic aldehyde"cinnamic aldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"17868967
D002953CitrininCitrinin results in increased phosphorylation of MAPK8 protein19361540
D007464Clioquinol[Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein16648635
D007464Clioquinol[Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein16648635
D007464Clioquinolpyrazolanthrone inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein]16648635
C000593591coagulin-Lcoagulin-L inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27568862
D003031CoalCoal affects the expression of MAPK8 mRNA24351557
C007095cobaltiprotoporphyrincobaltiprotoporphyrin results in decreased phosphorylation of MAPK8 protein22237591
C018021cobaltous chlorideAcetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]24386346
C018021cobaltous chloridecobaltous chloride results in increased phosphorylation of MAPK8 protein19101624|2438634
C018021cobaltous chlorideginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]24386346
C018021cobaltous chloridecobaltous chloride results in increased phosphorylation of MAPK8 protein21925238|2266971
C018021cobaltous chlorideProtein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]21925238
D003042Cocaineacetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]20354174
D003042CocaineAG 1879 inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]20354174
D003042CocaineCocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein20354174
D003042Cocaine"N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]"20354174
D003042CocaineSIGMAR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]20354174
D003078ColchicineColchicine results in increased phosphorylation of MAPK8 protein12221076
D003078ColchicineTP53 protein affects the reaction [Colchicine results in increased phosphorylation of MAPK8 protein]12221076
D003300Copper[Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein16648635
D003300CopperCopper inhibits the reaction [IAPP protein results in increased phosphorylation of MAPK8 protein]23793354
D003300Copper[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein24690739
D003300Copperpyrazolanthrone inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein]16648635
D003300Copper[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein24690739
D003300CopperAcetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]22085843
D003300Copperbathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein]18056745
D003300Copperbathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein]10941151
D003300Copper[Copper binds to neocuproine] which results in increased activity of MAPK8 protein18056745
D003300Copper[[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein18056745
D003300Copper[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein22085843
D003300Copperpyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]22085843
D003300Copper[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein10941151
C067957corticosterone-21-hemisuccinatecorticosterone-21-hemisuccinate results in increased phosphorylation of and results in increased activity of MAPK8 protein15961565
C408982CPG-oligonucleotideCPG-oligonucleotide results in increased phosphorylation of MAPK8 protein17209053
C029892cupric chloridebathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]11239917
C029892cupric chloride[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein11239917
C029892cupric chlorideMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]20920558
C029892cupric chlorideMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]20920558
C029892cupric chlorideMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]20920558
D003471CuprizoneCuprizone results in decreased expression of MAPK8 mRNA26577399
D003474CurcuminCurcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein]20727180
D003474CurcuminCurcumin results in increased expression of MAPK8 mRNA16101141
D003474CurcuminCurcumin results in increased phosphorylation of MAPK8 protein18316600
D003474CurcuminMAPK8 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]18316600
D003474CurcuminCurcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein]18321868
D003474CurcuminCurcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]16678799
D003474CurcuminCurcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]16934299
D003474CurcuminCurcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]24952339
D003474CurcuminCurcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]11981161
D003474CurcuminCurcumin results in decreased phosphorylation of and results in decreased activity of MAPK8 protein17372590
D003474CurcuminCurcumin results in decreased phosphorylation of MAPK8 protein18332871
D003474CurcuminCurcumin results in increased expression of MAPK818462866
D003520CyclophosphamideCyclophosphamide results in increased phosphorylation of MAPK8 protein19696094
D003520CyclophosphamideGSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]19696094
D003520CyclophosphamideGSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]19696094
D003520CyclophosphamideMesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]19696094
D003520CyclophosphamideMesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]19696094
D003520CyclophosphamideMesna inhibits the reaction [GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]19696094
D003520CyclophosphamideCyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein19996110
D003520CyclophosphamideNGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]19996110
D016572CyclosporineCyclosporine results in increased expression of MAPK8 mRNA25562108
D016572CyclosporineCyclosporine results in increased expression of MAPK8 protein10617104
C017160cypermethrincypermethrin results in increased expression of MAPK8 mRNA27704156
D003545CysteineMAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency]11312036
D003545Cysteine[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein11709198
D003545CysteineMAPK8 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D003545CysteineMAPK8 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D003545CysteineMAPK8 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]11709198
D003603Cytotoxins4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein]21147958
D003603CytotoxinsCytotoxins results in increased phosphorylation of MAPK8 protein21147958
D003603CytotoxinsEIF2AK3 protein affects the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein]21147958
D003603CytotoxinsERN1 protein affects the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein]21147958
D003634DDTDDT results in decreased phosphorylation of MAPK8 protein14604893
C010902decabromobiphenyl etherdecabromobiphenyl ether affects the expression of MAPK8 mRNA24834073
C017180decamethrindecamethrin results in decreased nitrosation of MAPK8 protein25299849
C017180decamethrinHistamine inhibits the reaction [decamethrin results in decreased nitrosation of MAPK8 protein]25299849
C014347decitabinedecitabine results in decreased expression of MAPK8 mRNA27915011
D003676DeferoxamineDeferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]20206247
D003676DeferoxamineDeferoxamine results in increased phosphorylation of MAPK8 protein20368581
C017185delphinidindelphinidin results in increased phosphorylation of and results in increased activity of MAPK8 protein15740068
D013759DronabinolDronabinol results in increased phosphorylation of MAPK8 protein24184660
D013759DronabinolSR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK8 protein]24184660
C007262deoxynivalenoldeoxynivalenol results in decreased activity of MAPK8 protein20708668
C007262deoxynivalenol[deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein20708668
C007262deoxynivalenoldeoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein18485432|1936075
C007262deoxynivalenol"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]"15772366
C007262deoxynivalenolAG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]15772366
C007262deoxynivalenoldeoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]14644621
C007262deoxynivalenoldeoxynivalenol results in increased phosphorylation of MAPK8 protein12377986|1260484
C007262deoxynivalenolDocosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]14690764|1557003
C007262deoxynivalenolEicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]14690764
C007262deoxynivalenolFish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]14690764
C494355desisobutyrylciclesonidedesisobutyrylciclesonide inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein]26003274
C494355desisobutyrylciclesonide[Formoterol Fumarate co-treated with desisobutyrylciclesonide] inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein]26003274
D003907DexamethasoneDexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]10807665
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]]10807665
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein]16880258
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27568862
D003907DexamethasoneDexamethasone inhibits the reaction [Zymosan results in increased phosphorylation of and results in increased activity of MAPK8 protein]10874129
D003907DexamethasoneDUSP1 protein promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein]]16880258
D003907DexamethasoneDexamethasone affects the phosphorylation of MAPK8 protein18234956
C028009diallyl disulfidediallyl disulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein17647244
C028009diallyl disulfidediallyl disulfide results in increased phosphorylation of MAPK8 protein14522920
D003973DiatrizoateDiatrizoate results in increased phosphorylation of MAPK8 protein21036957
D003975Diazepam[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein]21971501
D003976DiazinonDiazinon results in increased expression of MAPK8 mRNA29108742
C041517dibenzo(a,l)pyrene"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of MAPK8 mRNA]"22079312
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of MAPK8 mRNA"22079312
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of MAPK8 mRNA21266533
D002945Cisplatin"[Cisplatin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of MAPK8 protein"21214929
D002945CisplatinCisplatin results in increased phosphorylation of and results in increased activity of MAPK8 protein11592233
D002945CisplatinNicotine inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased activity of MAPK8 protein]11592233
D002945CisplatinCisplatin results in increased expression of MAPK8 mRNA20883750
D002945CisplatinCisplatin results in increased phosphorylation of MAPK8 protein25560393
D002945CisplatinCisplatin results in increased expression of MAPK8 protein modified form26739623
D002945CisplatinCisplatin results in increased phosphorylation of MAPK8 protein15147517
D002945CisplatinLovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form]26739623
D002945CisplatinN-Acetylcysteinamide inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein]15147517
D004008DiclofenacDiclofenac affects the expression of MAPK8 mRNA24752500
C000944dicrotophosdicrotophos results in decreased expression of MAPK8 mRNA28302478
D001728DicumarolDicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein]24466103
D001728DicumarolDicumarol inhibits the reaction [arsenic trioxide results in increased activity of MAPK8 protein]14701702
D018119StavudineStavudine results in decreased phosphorylation of MAPK8 protein27041070
D004041Dietary FatsDietary Fats results in increased phosphorylation of MAPK8 protein23118937
D004041Dietary FatsDietary Fats results in increased phosphorylation of MAPK8 protein22198281|2303800
D004041Dietary Fatsnaringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein]22198281
D004041Dietary FatsSodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]26522834
D004041Dietary Fats[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein26522834
D004041Dietary FatsTamoxifen inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein]23038002
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]15989949
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]18691550
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]18691550
D004052DiethylnitrosamineDiethylnitrosamine results in increased activity of MAPK8 protein15989949|1869155
D004052DiethylnitrosamineIKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]18691550
D004052DiethylnitrosamineMAPK8 promotes the reaction [NR1H4 gene mutant form results in increased susceptibility to Diethylnitrosamine]25496033
D004052DiethylnitrosamineMAPK8 protein results in increased susceptibility to Diethylnitrosamine16807293
D004052DiethylnitrosamineMAPK8 results in increased susceptibility to Diethylnitrosamine25496033
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA23830814
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK8 mRNA23830814
D004054DiethylstilbestrolDiethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK8 protein15171707
D002117CalcitriolCalcitriol results in decreased phosphorylation of and results in decreased activity of MAPK8 protein12761878
D0178784,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein]"19815690
D004110DiltiazemDiltiazem results in decreased activity of MAPK8 protein11937779
D004128DimethylnitrosamineDimethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK8 protein12971962
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased phosphorylation of MAPK8 protein18495191
D004139DinitrofluorobenzeneDinitrofluorobenzene results in increased phosphorylation of MAPK8 protein27129696
D004139DinitrofluorobenzeneFluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]27129696
C034638dinitrophenyl-bovine serum albumindesisobutyrylciclesonide inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein]26003274
C034638dinitrophenyl-bovine serum albumindinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein26003274
C034638dinitrophenyl-bovine serum albumin[Formoterol Fumarate co-treated with desisobutyrylciclesonide] inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein]26003274
C034638dinitrophenyl-bovine serum albuminFormoterol Fumarate inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein]26003274
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of MAPK8 mRNA28939011
D004155DiphenhydramineDiphenhydramine results in increased activity of MAPK817390763
C493087diphenylarsinic aciddiphenylarsinic acid results in increased phosphorylation of MAPK8 protein28087833
C493087diphenylarsinic acidSCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK8 protein]28087833
C493087diphenylarsinic acidU 0126 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK8 protein]28087833
C434247diphenylditelluridediphenylditelluride results in increased phosphorylation of MAPK8 protein22885153
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D004176DipyridamoleDipyridamole results in increased activity of MAPK8 protein11051267
D004221Disulfiram[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein24690739
D004221Disulfiram[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein24690739
D004221Disulfirambathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]11239917
D004221Disulfiram[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein11239917
D004229DithiothreitolDithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein]10644709
C478085D-JNKI-1D-JNKI-1 results in decreased activity of MAPK8 protein13679429
C560357DLJ14 compound[DLJ14 compound co-treated with Doxorubicin] results in increased phosphorylation of MAPK8 protein21402141
D004281Docosahexaenoic AcidsDocosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]14690764|1557003
C076946donepezildonepezil inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MAPK8 protein]19345205
D004298DopamineAcetylcysteine inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein]17481858
D004298DopamineDopamine results in increased phosphorylation of MAPK8 protein17481858
D004298DopamineGlutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein]17481858
D004317Doxorubicinbenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]15917298
D004317Doxorubicin[DLJ14 compound co-treated with Doxorubicin] results in increased phosphorylation of MAPK8 protein21402141
D004317DoxorubicinDoxorubicin affects the activity of MAPK8 protein15870702
D004317Doxorubicin"[Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of MAPK8 protein"21214929
D004317Doxorubicin[Doxorubicin co-treated with Phellinus linteus extract] results in increased expression of and results in increased phosphorylation of and results in increased activity of MAPK8 protein16868541
D004317DoxorubicinDoxorubicin results in increased activity of MAPK8 protein15880572
D004317DoxorubicinDoxorubicin results in increased phosphorylation of and results in increased activity of MAPK8 protein15494689
D004317DoxorubicinDoxorubicin results in increased phosphorylation of MAPK8 protein15917298|1689018
D004317DoxorubicinGSTA1 protein inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]16890185
D004317DoxorubicinMAPK8 protein results in increased susceptibility to Doxorubicin15917298
D004317Doxorubicinrottlerin inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]15917298
D004317DoxorubicinDoxorubicin results in increased expression of MAPK8 mRNA26335259
D004317DoxorubicinDoxorubicin results in increased phosphorylation of and results in increased activity of MAPK8 protein18346979
D004317DoxorubicinDoxorubicin results in increased phosphorylation of MAPK8 protein15623433|1621347
D004317Doxorubicin[Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased expression of MAPK8 mRNA]26335259
D004317Doxorubicin[Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]26335259
D004317DoxorubicinTaurine inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]26335259
C060327dracorhodindracorhodin analog results in increased phosphorylation of MAPK8 protein15684474|1686444
C060327dracorhodinpyrazolanthrone inhibits the reaction [dracorhodin analog results in increased phosphorylation of MAPK8 protein]16864444
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased activity of MAPK8 protein"17996228
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased phosphorylation of MAPK8 protein"15894585
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK8 mRNA]"28757890
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK8 protein modified form]"28757890
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased phosphorylation of MAPK8 protein"19647727
C098320efavirenzAcetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]21958719
C098320efavirenzAcetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]21958719
C098320efavirenzefavirenz metabolite results in increased phosphorylation of MAPK8 protein21958719
C098320efavirenzefavirenz results in increased phosphorylation of MAPK8 protein21958719
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]15254339
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]11981161
D015118Eicosapentaenoic AcidEicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]14690764
D015118Eicosapentaenoic AcidEicosapentaenoic Acid promotes the reaction [[Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein]22169119
D015118Eicosapentaenoic Acid[Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in decreased phosphorylation of MAPK8 protein22169119
D015118Eicosapentaenoic Acidprocyanidin B3 promotes the reaction [[Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in decreased phosphorylation of MAPK8 protein]22169119
D004610Ellagic Acid[Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein15735102
D004640Emetine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK8 protein]"15772366
D004640EmetineEmetine results in increased phosphorylation of MAPK8 protein15772366
C118739entinostat[3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with entinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein15964800
C118739entinostatentinostat results in decreased expression of MAPK8 mRNA27188386
D010697Eosine I Bluish[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein24488945
D010697Eosine I BluishCAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein]24488945
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein]19944065
C045651epigallocatechin gallateepigallocatechin gallate results in increased activity of MAPK8 protein15705601
C007619eriodictyoleriodictyol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21544733
C007628esculetin[esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein16051289
C007628esculetinesculetin results in increased expression of MAPK8 protein16051289
C007628esculetinesculetin results in increased phosphorylation of MAPK8 protein19786087
C007628esculetinBCL2 protein inhibits the reaction [esculetin results in increased phosphorylation of MAPK8 protein]19786087
C007633estragoleestragole results in increased phosphorylation of MAPK8 protein29054680
D004967Estrogens[Estrogens co-treated with Progesterone] results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of MAPK8 protein18486349
D004976Ethacrynic AcidEthacrynic Acid results in decreased expression of MAPK8 protein14556662
D000431EthanolEthanol results in increased phosphorylation of MAPK8 protein28062356
D000431EthanolEthanol results in increased phosphorylation of MAPK8 protein28119953
D000431EthanolEthanol results in increased phosphorylation of MAPK8 protein19735724
D000431EthanolPolysaccharides inhibits the reaction [Ethanol results in increased phosphorylation of MAPK8 protein]19735724
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of MAPK8 mRNA17606305
C456800ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK8 protein15634644
C503624eupafolineupafolin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]24967690
C049639evodiamine"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [evodiamine results in increased expression of MAPK8 protein modified form]"23774672
C049639evodiamineevodiamine results in increased expression of MAPK8 protein modified form23774672
D018683Excitatory Amino Acid AgentsExcitatory Amino Acid Agents results in increased expression of MAPK8 protein20955365
D018683Excitatory Amino Acid AgentsExcitatory Amino Acid Agents results in increased phosphorylation of and results in increased activity of MAPK8 protein20542495
D018683Excitatory Amino Acid AgentsExcitatory Amino Acid Agents results in increased phosphorylation of MAPK8 protein20955365
D018683Excitatory Amino Acid AgentsMAPK8 protein promotes the reaction [Excitatory Amino Acid Agents results in increased expression of GADD45A protein]20955365
D018683Excitatory Amino Acid AgentsMAPK8 protein promotes the reaction [Excitatory Amino Acid Agents results in increased expression of TRP53 protein]20955365
D018683Excitatory Amino Acid AgentsMAPK8 protein results in increased susceptibility to Excitatory Amino Acid Agents20955365
D018683Excitatory Amino Acid Agentsresveratrol inhibits the reaction [Excitatory Amino Acid Agents results in increased phosphorylation of and results in increased activity of MAPK8 protein]20542495
D015025ZearalenoneZearalenone results in increased phosphorylation of MAPK8 protein21767629
C004808farnesyl pyrophosphatefarnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]]18310456
C004999ferulic acidferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein]21291945
C004999ferulic acidferulic acid results in decreased activity of MAPK8 protein15363954
D005395Fish OilsFish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]14690764
D0150732-Acetylaminofluorene2-Acetylaminofluorene affects the phosphorylation of and affects the activity of MAPK8 protein17546627
D016650Fluorescein-5-isothiocyanateFluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]27129696
D016650Fluorescein-5-isothiocyanateFluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27129696
D016650Fluorescein-5-isothiocyanateFluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein27129696
D005473FluoxetineFluoxetine results in decreased expression of MAPK8 mRNA20924750
D005485FlutamideFlutamide results in increased expression of MAPK8 mRNA24136188
D005492Folic AcidFolic Acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21528358
D000068759Formoterol Fumarate[Formoterol Fumarate co-treated with desisobutyrylciclesonide] inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein]26003274
D000068759Formoterol FumarateFormoterol Fumarate inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein]26003274
D009240N-Formylmethionine Leucyl-PhenylalanineN-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein17377739
D009240N-Formylmethionine Leucyl-Phenylalaninenordy inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein]17377739
D009240N-Formylmethionine Leucyl-PhenylalanineMAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species]17560994
D009240N-Formylmethionine Leucyl-PhenylalanineN-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein17560994
C058728fosbretabulinMAPK8 protein affects the susceptibility to fosbretabulin24321340
D037741FullerenesFullerenes analog results in increased expression of MAPK8 mRNA22342292
C005023fulvic acidfulvic acid inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK8 protein]25888188
C005023fulvic acidfulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA]21331654
D062610Fungal PolysaccharidesFungal Polysaccharides results in increased expression of MAPK8 protein modified form24447977
D005707Gallic AcidGallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]21420233
C419708gefitinibgefitinib results in increased phosphorylation of MAPK8 protein20846305
D005839GentamicinsCAT protein inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein]15936777
D005839GentamicinsEstradiol inhibits the reaction [Gentamicins results in increased activity of MAPK8 protein]20074632
D005839GentamicinsGentamicins results in increased activity of MAPK8 protein20074632
D005839GentamicinsGentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein15936777
D005839GentamicinsGentamicins results in increased phosphorylation of MAPK8 protein16401625
D005839Gentamicinsicatibant inhibits the reaction [KLK1 protein inhibits the reaction [Gentamicins results in increased phosphorylation of MAPK8 protein]]16401625
D005839GentamicinsKLK1 protein inhibits the reaction [Gentamicins results in increased phosphorylation of MAPK8 protein]16401625
D005839GentamicinsVerapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein]15936777
C063170Ginkgo biloba extractGinkgo biloba extract affects the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]19414004
C063170Ginkgo biloba extractGinkgo biloba extract inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]19464278
C045856ginkgolide Bginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]19464278
C035054ginsenoside Rg1ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]24386346
D005912GliotoxinGliotoxin results in increased phosphorylation of and results in increased activity of MAPK8 protein17466404
D005936GlucansGlucans results in increased phosphorylation of MAPK8 protein19041413
D005944GlucosamineGlucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]18080321
D005944GlucosamineGlucosamine analog results in increased phosphorylation of MAPK8 protein18080321
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]19626664
D005944GlucosamineGlucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]20307528
D005947GlucoseGlucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein14505347
D005947GlucoseGlucose results in increased phosphorylation of MAPK8 protein19861503
D005947GlucoseCAT protein inhibits the reaction [Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein]14505347
D005947Glucose[CAT protein promotes the reaction [TXN protein binds to and results in decreased activity of MAP3K5 protein]] inhibits the reaction [Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein]14505347
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of MAPK8 mRNA22634610
D005978GlutathioneGlutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23816505
D005978GlutathioneGlutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]23816505
D005978GlutathioneGlutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]16112521
D005978GlutathioneGlutathione inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]20423716
D005978GlutathioneGlutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein]17481858
D005978GlutathioneGlutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]22767315
C086854glycine-extended gastrin 17Celecoxib inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein]16442704
C086854glycine-extended gastrin 17glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein16442704
C086854glycine-extended gastrin 17pyrazolanthrone inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein]16442704
C081021Go 6976"Go 6976 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased phosphorylation of MAPK8 protein]"28087840
D006151GuanosineGuanosine inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein]17175248
D006152Cyclic GMPCyclic GMP analog results in increased activity of MAPK8 protein11051267
C412815GW 4064GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]25496033
C412815GW 4064NR1H4 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]25496033
C412815GW 4064SOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]25496033
C412815GW 4064GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]25496033
C412815GW 4064GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]25496033
C412815GW 4064GW 4064 results in increased expression of MAPK8 mRNA26655953
C411572H 1356H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein]]25309793
D006220HaloperidolHaloperidol results in increased phosphorylation of MAPK8 protein17092607
D006220HaloperidolINS protein inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK8 protein]17092607
D006427HeminHemin promotes the reaction [Paraquat results in increased phosphorylation of MAPK8 protein]19080378
D006569HesperidinHesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein]19110045
D006581HexachlorobenzeneHexachlorobenzene results in increased phosphorylation of MAPK8 protein23708402
D006632HistamineHistamine inhibits the reaction [decamethrin results in decreased nitrosation of MAPK8 protein]25299849
D017313FenretinideButylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK8 protein]16407847
D017313FenretinideFenretinide results in increased activity of MAPK8 protein16407847
D017313FenretinideFenretinide results in increased phosphorylation of MAPK8 protein16407847
D017313Fenretinide[IL24 protein co-treated with Fenretinide] results in increased phosphorylation of MAPK8 protein15580305
D017313FenretinideMAPK8 protein promotes the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313FenretinideMAPK8 protein promotes the reaction [Fenretinide results in increased phosphorylation of JUN protein]16407847
C062018HU 211HU 211 results in increased phosphorylation of MAPK8 protein16046413|1895062
C062018HU 211rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein]18950629
C062018HU 211wortmannin inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein]18950629
D006861Hydrogen PeroxideAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23816505
D006861Hydrogen PeroxideGlutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23816505
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK8 protein23816505
D006861Hydrogen Peroxidepyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23816505
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of and results in increased activity of MAPK8 protein15328380
D006861Hydrogen Peroxide2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]28213291
D006861Hydrogen PeroxideGinkgo biloba extract affects the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]19414004
D006861Hydrogen PeroxideGW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]25496033
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of MAPK8 protein21179406
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]12684028
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein]10910949
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of MAPK8 protein12215205|1290219
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of and results in increased activity of MAPK8 protein12684028|1941400
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK8 protein10910949|1579542
D006861Hydrogen PeroxideMycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]20302854
D006861Hydrogen Peroxidemyricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23639522
D006861Hydrogen PeroxideNR1H4 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]25496033
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]15795422
D006861Hydrogen PeroxideSOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]25496033
D006861Hydrogen PeroxideChenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]25496033
D006861Hydrogen PeroxideGSTA4 protein inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]15064094
D006861Hydrogen PeroxideGW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]25496033
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of MAPK8 protein10843682|1118182
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK8 protein15064094|2549603
D006861Hydrogen PeroxideTXNIP promotes the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]10843682
D006861Hydrogen Peroxide"2-(4-((dimethylamino)methyl)benzylidene)-5,6-dimethoxy-2,3-dihydroinden-1-one inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MAPK8 protein]"19345205
D006861Hydrogen PeroxideAG 1879 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
D006861Hydrogen Peroxidedonepezil inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MAPK8 protein]19345205
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of MAPK8 protein15574683
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of and results in increased activity of MAPK8 protein11562448|1938602
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK8 protein16284289|1636242
D006861Hydrogen Peroxidemarimastat inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
D006861Hydrogen PeroxideN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
D006861Hydrogen PeroxidePPP2CA protein inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]19038359
D006861Hydrogen PeroxidePPP5C protein inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]19038359
D006861Hydrogen Peroxidepramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]16362428
D006861Hydrogen PeroxideProgesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]16284289
D006861Hydrogen Peroxidepyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]19038359
D006861Hydrogen Peroxidetyrphostin AG 1478 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK8 protein11325585|1808666
D006861Hydrogen PeroxideMAPK8 protein affects the susceptibility to [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of FOXO4 protein]15538382
D006918HydroxyureaHydroxyurea results in decreased phosphorylation of MAPK8 protein15557822
D006997Hypochlorous AcidHypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein18156441
C065679icatibanticatibant inhibits the reaction [KLK1 protein inhibits the reaction [Gentamicins results in increased phosphorylation of MAPK8 protein]]16401625
C514526indole-5-carboxamideindole-5-carboxamide promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]16818652
C057937iomeproliomeprol results in increased phosphorylation of MAPK8 protein21036957
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MAPK8 mRNA25613284
C550177isoliquiritigenin 2'-methyl etherisoliquiritigenin 2'-methyl ether results in increased phosphorylation of MAPK8 protein20040371
D007545Isoproterenolcandesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]20562518
D007545IsoproterenolIsoproterenol results in increased phosphorylation of MAPK8 protein20562518
D007545Isoproterenol2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]15951400
D007545IsoproterenolIsoproterenol results in increased activity of MAPK8 protein10591028
D007545IsoproterenolIsoproterenol results in increased phosphorylation of MAPK8 protein15951400
C432307isorhapontigeninisorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein]15607907
D007559Ivermectin"Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]"19168156
C544151jinfukangjinfukang results in decreased expression of MAPK8 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of MAPK8 mRNA23828858
C063587juzentaihotojuzentaihoto inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]15778123
D007612KanamycinKanamycin results in increased phosphorylation of MAPK8 protein17570507
D007654KetoconazoleKetoconazole results in increased phosphorylation of MAPK8 protein19631732
D007654KetoconazoleKetoconazole results in increased expression of MAPK8 mRNA25787151
C072105KN 93KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21933187
C011890kojic acidkojic acid results in decreased expression of MAPK8 mRNA16595896
C508710L-826266L-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK8 protein]16644903
C500368labedipinedilol Alabedipinedilol A results in increased activity of MAPK8 protein19056458
C067713lactacystinlactacystin results in increased activity of MAPK8 protein15618349
C067713lactacystinlactacystin results in increased activity of MAPK8 protein15618349
C067713lactacystinlactacystin results in increased phosphorylation of MAPK8 protein18463101
C008261lead acetate2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein]20829427
C008261lead acetate[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein20829427
C008261lead acetatelead acetate affects the expression of MAPK824293362
C008261lead acetatelead acetate results in increased phosphorylation of MAPK8 protein25088297
C008261lead acetateProanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of MAPK8 protein]25088297
C029891lead chloridelead chloride results in increased expression of MAPK8 protein modified form24419708
C523615levistolide A[levistolide A co-treated with PDGFB protein] results in increased phosphorylation of MAPK8 protein17520522
C541528licochalcone Blicochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]25451593
D001556LindaneLindane results in increased phosphorylation of and results in increased activity of MAPK8 protein23927878
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein"21647617
C482199lipopolysaccharide, E coli O55-B5"1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]"21667204
C482199lipopolysaccharide, E coli O55-B5"Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]"19168156
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein"19168156|2166720
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein"21430222
C440499lipopolysaccharide, Escherichia coli O111 B4"2'-benzoyloxycinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"20933287
C440499lipopolysaccharide, Escherichia coli O111 B4"alpha-chaconine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"25913072
C440499lipopolysaccharide, Escherichia coli O111 B4"Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"23238562
C440499lipopolysaccharide, Escherichia coli O111 B4"cinnamic aldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"17868967
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein"17868967|2093328
C440499lipopolysaccharide, Escherichia coli O111 B4"p-hydroxycinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"20933287
C440499lipopolysaccharide, Escherichia coli O111 B4"Plant Extracts inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"21537903
C440499lipopolysaccharide, Escherichia coli O111 B4"TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]]"23238562
D008070Lipopolysaccharides"1,6-hexamethylene diisocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]"27129696
D008070Lipopolysaccharidesacetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D008070Lipopolysaccharidesacetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]24967690
D008070LipopolysaccharidesAcetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D008070LipopolysaccharidesCBR1 protein modified form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]25818598
D008070LipopolysaccharidesCEP-11004 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]17698565
D008070Lipopolysaccharidesdiphenyleneiodonium inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D008070LipopolysaccharidesDUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]]21911040
D008070Lipopolysaccharideseupafolin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]24967690
D008070LipopolysaccharidesFluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27129696
D008070LipopolysaccharidesGlucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]20307528
D008070Lipopolysaccharides[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein21391979
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of MAPK8 protein20307528|2111266
D008070LipopolysaccharidesMAPK8 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of BAG3 protein]22020323
D008070Lipopolysaccharidesphthalic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27129696
D008070LipopolysaccharidesTLR2 protein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21112663
D008070Lipopolysaccharidestrichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21911040
D008070Lipopolysaccharidestrimellitic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27129696
D008070Lipopolysaccharidesaciculatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21548916
D008070LipopolysaccharidesCD14 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]11123339
D008070LipopolysaccharidesChalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]22155221
D008070Lipopolysaccharidescoagulin-L inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27568862
D008070LipopolysaccharidesCurcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]16678799
D008070Lipopolysaccharidesdeoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]14644621
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein]16880258
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27568862
D008070LipopolysaccharidesDUSP1 protein promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein]]16880258
D008070LipopolysaccharidesEicosapentaenoic Acid promotes the reaction [[Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein]22169119
D008070Lipopolysaccharideseriodictyol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21544733
D008070LipopolysaccharidesFolic Acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21528358
D008070LipopolysaccharidesGSTP1 protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]16023107
D008070LipopolysaccharidesITGAM protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]11123339
D008070Lipopolysaccharidesjuzentaihoto inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]15778123
D008070Lipopolysaccharideslicochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]25451593
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in decreased phosphorylation of MAPK8 protein22169119
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK8 protein23362215|2383130
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein22169119
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of MAPK8 protein modified form15832817
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein12619901|1688025
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of MAPK8 protein11123339|1464462
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]15933225
D008070LipopolysaccharidesPlant Extracts inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21465277
D008070Lipopolysaccharidesprocyanidin B3 promotes the reaction [[Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in decreased phosphorylation of MAPK8 protein]22169119
D008070LipopolysaccharidesSodium Selenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein]18481333
D008070Lipopolysaccharidessoyasaponin Ab inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]22060784
D008070Lipopolysaccharideswogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK8 protein]23362215
D008070LipopolysaccharidesApigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]25557508
D008070LipopolysaccharidesCurcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]16934299
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of MAPK8 protein16934299|1804756
D008070LipopolysaccharidesSimvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]18047562
C009900lipoteichoic acid[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein23238562
C009900lipoteichoic acidTIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]23238562
D008094LithiumLithium results in increased expression of MAPK8 protein18296634
D008094LithiumLithium results in increased phosphorylation of MAPK8 protein18296634
C118715LL Z1640-2LL Z1640-2 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]15081267
C581034longikaurin AAcetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein]28801140
C581034longikaurin Alongikaurin A results in increased phosphorylation of MAPK8 protein28801140
D008148LovastatinLovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form]26739623
D047311LuteolinLuteolin promotes the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]15334063
D047311LuteolinLuteolin results in decreased phosphorylation of and results in decreased activity of MAPK8 protein10718847
D047311LuteolinLuteolin results in increased phosphorylation of MAPK8 protein21601631
C094099LY 293111LY 293111 results in increased expression of MAPK8 protein modified form16151469
C094099LY 293111pyrazolanthrone inhibits the reaction [LY 293111 results in increased expression of MAPK8 protein modified form]16151469
C015329lycopenelycopene results in decreased expression of MAPK8 protein17337101
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of MAPK8 mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of MAPK8 mRNA26378955
C005498magnololmagnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein]26756313
C005095malachite greenmalachite green results in decreased phosphorylation of MAPK8 protein16675904
C005095malachite greenmalachite green results in increased phosphorylation of MAPK8 protein16297712
D008315MalondialdehydeMAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA]11295527
D008345ManganeseManganese results in increased phosphorylation of MAPK8 protein17045426
C025340manganese chloridemanganese chloride results in increased activity of MAPK8 protein20152896
C025340manganese chloridemanganese chloride results in increased methylation of MAPK8 gene27913844
C025340manganese chloridemanganese chloride results in increased phosphorylation of MAPK8 protein19084589|2015289
C025340manganese chloridemanganese chloride results in increased phosphorylation of MAPK8 protein24324973
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form]17395008
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]10397638
C013592mangiferinmangiferin results in decreased expression of MAPK8 mRNA15135318
D008353MannitolMannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein]10910949
C054474manumycinmanumycin inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein]19739265
C100342marimastatmarimastat inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
D009637MasoprocolMasoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form]17395008
D008463MebendazoleMebendazole results in increased phosphorylation of MAPK8 protein20848085
D008464MecamylamineMecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein]18222492
D008466MechlorethamineMechlorethamine results in increased phosphorylation of MAPK8 protein25891025
D008550MelatoninMelatonin results in increased expression of MAPK8 protein19012662
D008610MentholMenthol results in increased phosphorylation of MAPK8 protein18955132
D015080MesnaMesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]19696094
D015080MesnaMesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]19696094
D015080MesnaMesna inhibits the reaction [GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]19696094
D008623MercaptoethanolMercaptoethanol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein]10644709
D008627Mercuric ChlorideMercuric Chloride results in increased phosphorylation of MAPK8 protein10861847|1288308
D008627Mercuric ChlorideMercuric Chloride results in increased phosphorylation of MAPK8 protein10696784
D008715MethionineMethionine deficiency results in increased activity of MAPK8 protein11880182
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein23038002
D008715MethionineTamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein]23038002
D008715MethionineMAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency]11312036
D008715Methionine[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein11709198
D008715MethionineMAPK8 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D008715MethionineMAPK8 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D008715MethionineMAPK8 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]11709198
D008727MethotrexateMAPK8 gene mutant form inhibits the reaction [Methotrexate results in increased expression of CDKN1A protein]22183962
D008727MethotrexateMethotrexate results in increased phosphorylation of MAPK8 protein20885979
D008731MethoxychlorMethoxychlor results in increased expression of MAPK8 mRNA20829426
C587228methyl 3-hydroxyimino-11-oxoolean-12-en-28-oatemethyl 3-hydroxyimino-11-oxoolean-12-en-28-oate results in decreased expression of and results in decreased phosphorylation of MAPK8 protein24291674
C014659methyl(acetoxymethyl)nitrosaminemethyl(acetoxymethyl)nitrosamine results in increased phosphorylation of and results in increased activity of MAPK8 protein12693035
D008748MethylcholanthreneMethylcholanthrene results in increased phosphorylation of and results in increased activity of MAPK8 protein16619036
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]15933225
C004925methylmercuric chloridemethylmercuric chloride results in increased phosphorylation of MAPK8 protein27667695
D008767Methylmercury CompoundsMethylmercury Compounds results in increased phosphorylation of MAPK8 protein19666049
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein22001597
D008770MethylnitrosoureaButylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]18593901
D008770MethylnitrosoureaMAPK8 gene mutant form results in decreased susceptibility to Methylnitrosourea18593901
D008770MethylnitrosoureaMAPK8 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein]18593901
D008770MethylnitrosoureaMethylnitrosourea results in increased activity of MAPK8 protein18593901
D008770MethylnitrosoureaButylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]18593901
D008770MethylnitrosoureaMethylnitrosourea results in increased activity of MAPK8 protein18593901
D008770MethylnitrosoureaMethylnitrosourea results in increased phosphorylation of and results in increased activity of MAPK8 protein12693035
D008770MethylnitrosoureaMethylnitrosourea results in increased phosphorylation of MAPK8 protein16168987
D008770MethylnitrosoureaNiacinamide inhibits the reaction [Methylnitrosourea results in increased phosphorylation of MAPK8 protein]16168987
D008774MethylphenidateMethylphenidate results in increased expression of MAPK8 mRNA22470460
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein17240529
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of MAPK8 mRNA25234470
D0156551-Methyl-4-phenylpyridiniumRNF7 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein]17240529
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein11181820
C008493methylselenic acidmethylselenic acid results in increased expression of MAPK8 mRNA12517777
D008825MiconazoleMiconazole results in increased expression of MAPK8 mRNA22262564
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]]10807665
D008911MinocyclineMinocycline results in decreased phosphorylation of MAPK8 protein17872917
D016685MitomycinMitomycin results in increased activity of and results in increased phosphorylation of MAPK8 protein16186332
C568376MT19c compoundMT19c compound results in increased phosphorylation of and results in increased activity of MAPK8 protein21803404
D009151Mustard GasMustard Gas results in increased phosphorylation of MAPK8 protein18200059
C052490MY 5445MY 5445 results in increased activity of MAPK8 protein11051267
D009173Mycophenolic AcidMycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]20302854
D009173Mycophenolic AcidGuanosine inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein]17175248
D009173Mycophenolic AcidMycophenolic Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein17175248
D009173Mycophenolic AcidMycophenolic Acid results in decreased expression of MAPK8 protein modified form20302854
C008577myricitrinmyricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23639522
C097963N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin"N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]"20354174
C078131N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamideN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
C001020N(6),N(6)-dimethyladenine"N(6),N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]"15618353
C487056N-AcetylcysteinamideN-Acetylcysteinamide inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein]15147517
C005273naringeninnaringenin results in increased phosphorylation of MAPK8 protein27838343
C005274naringinnaringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein]22198281
C017096n-butoxyethanoln-butoxyethanol results in decreased expression of MAPK8 mRNA19812364
C002701neocuproinebathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein]18056745
C002701neocuproine[Copper binds to neocuproine] which results in increased activity of MAPK8 protein18056745
C002701neocuproine[[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein18056745
C022838nickel chlorideMAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 mRNA]17065197
C022838nickel chlorideMAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 protein]17065197
C022838nickel chloridenickel chloride results in increased phosphorylation of MAPK8 protein21843586
C022838nickel chloridepyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK8 protein]21843586
C029938nickel sulfatenickel sulfate results in increased phosphorylation of MAPK8 protein15588916|1849519
C029938nickel sulfatepyrazolanthrone inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]18495191
C029938nickel sulfateSB 203580 promotes the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]18495191
C029938nickel sulfateMAP3K1 protein affects the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]18467339
C029938nickel sulfatenickel sulfate results in increased phosphorylation of MAPK8 protein18467339
C029938nickel sulfate[IFNG protein co-treated with nickel sulfate] results in increased phosphorylation of MAPK8 protein20525893
C017558nickel sulfideMAPK8 affects the reaction [nickel sulfide results in increased expression of PTGS2 protein]17065197
D009538NicotineCurcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein]20727180
D009538NicotineNicotine inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased activity of MAPK8 protein]11592233
D009538NicotineNicotine results in increased phosphorylation of MAPK8 protein20727180
D009538NicotineTP53 protein affects the reaction [Nicotine results in increased phosphorylation of MAPK8 protein]20727180
D009538NicotineNicotine results in increased phosphorylation of MAPK8 protein21511693
D009538NicotineNicotine promotes the reaction [MAPK8 protein results in increased phosphorylation of JUN protein]17021677
D009538NicotineNicotine results in increased activity of MAPK8 protein17021677
D009538NicotineNicotine results in increased expression of MAPK8 mRNA20426880
D009589Nitrogen OxidesNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein]16041517
D009599NitroprussideMAPK8 protein affects the susceptibility to Nitroprusside20132804
D009599NitroprussideMAPK8 protein affects the susceptibility to [Nitroprusside results in decreased expression of BCL2L1 mRNA]20132804
D009599NitroprussideNitroprusside results in decreased expression of MAPK8 protein modified form20132804
D009605NitrosomethylurethaneNitrosomethylurethane results in increased phosphorylation of and results in increased activity of MAPK8 protein12693035
D015739NocodazoleNocodazole results in increased phosphorylation of MAPK8 protein12221076
D015739NocodazoleTP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK8 protein]12221076
C069741norcantharidinnorcantharidin results in increased phosphorylation of MAPK8 protein21266192
C510003nordynordy inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein]17377739
D009638NorepinephrineAcetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein]17041759
D009638NorepinephrineNorepinephrine results in increased phosphorylation of MAPK8 protein17041759
C072936notoginsenoside R1notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein]24975829
C404397NSC 680410NSC 680410 results in increased phosphorylation of MAPK8 protein14647418
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein]"15210857
C495194O(2)-(2,4-dinitrophenyl) 1-(4-(N,N-diethylcarboxamido)piperazin-1-yl)diazen-1-ium 1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-(4-(N,N-diethylcarboxamido)piperazin-1-yl)diazen-1-ium 1,2-diolate promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein]"15210857
C107010O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate"O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [sodium arsenite results in increased activity of MAPK8 protein]"17658681
C025589ochratoxin Aochratoxin A results in increased phosphorylation of and results in increased activity of MAPK8 protein17651772
D016627OxidopamineOxidopamine results in increased phosphorylation of MAPK8 protein18675900
D016627Oxidopaminepuag-haad inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein]18675900
D016627OxidopamineAcetylcysteine inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]10397638
D016627Oxidopaminemanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]10397638
D016627OxidopamineOxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]10397638
D016627OxidopamineOxidopamine results in increased phosphorylation of MAPK8 protein23274087|2544685
D016627Oxidopaminesalvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein]25446857
D019319Okadaic AcidOkadaic Acid results in increased expression of MAPK8 mRNA28939011
D009828Oleanolic AcidOleanolic Acid analog results in decreased phosphorylation of MAPK8 protein26612655
C488250oleoylethanolamideMAPK8 protein promotes the reaction [oleoylethanolamide affects the phosphorylation of and affects the activity of INSR protein]19345745
C488250oleoylethanolamideoleoylethanolamide results in increased phosphorylation of and results in increased activity of MAPK8 protein19345745
C437965olmesartanolmesartan results in decreased activity of MAPK8 protein17208988
C437965olmesartanolmesartan results in decreased expression of MAPK8 protein modified form17208988
C016340o,p'-DDT"o,p'-DDT results in increased phosphorylation of MAPK8 protein"20678559
C016340o,p'-DDT"pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased phosphorylation of MAPK8 protein]"20678559
C016340o,p'-DDT"o,p'-DDT results in increased phosphorylation of and results in increased activity of MAPK8 protein"18840457
C016340o,p'-DDT"pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased phosphorylation of and results in increased activity of MAPK8 protein]"18840457
C432447ovatodiolideovatodiolide results in decreased phosphorylation of MAPK8 protein22033475
D010100OxygenMAPK8 protein affects the reaction [Oxygen deficiency results in increased expression of BACE1 protein]19196431
D010100OxygenOxygen deficiency results in increased activity of MAPK8 protein10780954|1367921
D010100OxygenOxygen deficiency results in increased phosphorylation of MAPK8 protein19196431
D010100OxygenSB 203580 inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]13679210
D010100OxygenSLC2A1 protein inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]10780954
D010100OxygenTXN protein promotes the reaction [Oxygen results in increased phosphorylation of MAPK8 protein]20812253
D010100Oxygen"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]]"27274199
D010100Oxygen[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein27274199
D010100OxygenOxygen deficiency results in increased activity of MAPK8 protein12892836
D010100OxygenOxygen results in increased phosphorylation of MAPK8 protein20812253
D010100OxygenTacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]12892836
D010100Oxygenursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]27274199
D010126OzoneOzone results in increased phosphorylation of MAPK8 protein19536146
D017239Paclitaxelaspartyl-glutamyl-valyl-aspartal inhibits the reaction [Paclitaxel results in increased activity of MAPK8 protein]11160861
D017239Paclitaxelepigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein]19944065
D017239Paclitaxel[esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein16051289
D017239PaclitaxelMAP3K1 protein affects the reaction [Paclitaxel results in increased activity of MAPK8 protein]11160861
D017239PaclitaxelMAPK8 protein affects the reaction [Paclitaxel results in increased activity of CASP3 protein]10075725
D017239PaclitaxelMAPK8 protein affects the reaction [Paclitaxel results in increased cleavage of PARP1 protein]10075725
D017239PaclitaxelMAPK8 protein affects the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein]11160861
D017239Paclitaxel[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein19944065
D017239PaclitaxelPaclitaxel promotes the reaction [MAPK8 protein binds to MAP3K1 protein modified form]11160861
D017239PaclitaxelPaclitaxel results in increased activity of MAPK8 protein11160861
D017239PaclitaxelPaclitaxel results in increased expression of MAPK8 protein16051289
D017239PaclitaxelCD14 protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein]11123339
D017239PaclitaxelITGAM protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein]11123339
D017239PaclitaxelPaclitaxel results in increased phosphorylation of MAPK8 protein11123339
C000588809paederosidic acidMAPK8 protein affects the reaction [paederosidic acid results in decreased expression of BCL2 protein]28185768
C000588809paederosidic acidMAPK8 protein affects the reaction [paederosidic acid results in increased cleavage of CASP3 protein]28185768
C000588809paederosidic acidMAPK8 protein affects the reaction [paederosidic acid results in increased cleavage of CASP8 protein]28185768
C000588809paederosidic acidMAPK8 protein affects the reaction [paederosidic acid results in increased cleavage of CASP9 protein]28185768
C000588809paederosidic acidMAPK8 protein affects the reaction [paederosidic acid results in increased expression of BAX protein]28185768
C000588809paederosidic acidMAPK8 protein affects the reaction [paederosidic acid results in increased expression of BID protein]28185768
D019308Palmitic AcidCapsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]21745629
D019308Palmitic AcidPalmitic Acid results in increased phosphorylation of MAPK8 protein21745629
D019308Palmitic AcidChromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]21134603
D019308Palmitic AcidPalmitic Acid results in increased phosphorylation of MAPK8 protein21134603
D010269ParaquatJAFRAC1 protein inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein]19720829
D010269ParaquatParaquat results in increased phosphorylation of MAPK8 protein19720829
D010269ParaquatMAPK8 protein affects the reaction [Paraquat results in increased expression of MUC5AC mRNA]25177032
D010269ParaquatParaquat results in increased phosphorylation of and results in increased activity of MAPK8 protein17018646
D010269ParaquatHemin promotes the reaction [Paraquat results in increased phosphorylation of MAPK8 protein]19080378
D010269ParaquatParaquat results in increased phosphorylation of MAPK8 protein16687388|1908037
D010269Paraquatpyrazolanthrone inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein]16687388
D017374ParoxetineParoxetine results in increased activity of MAPK8 protein17728140
D017374Paroxetinepyrazolanthrone inhibits the reaction [Paroxetine results in increased phosphorylation of and results in increased activity of MAPK8 protein]17728140
C002669parthenolideparthenolide results in increased expression of MAPK8 mRNA16921510
C002669parthenolideparthenolide results in increased phosphorylation of and results in increased activity of MAPK8 protein16921510
D052638Particulate MatterParticulate Matter results in increased phosphorylation of MAPK8 protein23900936
D052638Particulate MatterParticulate Matter results in increased phosphorylation of MAPK8 protein14565943
D052638Particulate MatterParticulate Matter results in increased expression of MAPK8 mRNA24216475
C509204PD168393"PD168393 inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of MAPK8 protein]"16778083
C074968pentaacetyl geniposidepentaacetyl geniposide results in increased phosphorylation of MAPK8 protein17651887
C074968pentaacetyl geniposidepyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein]17651887
C046012pentanalpentanal results in decreased expression of MAPK8 mRNA26079696
D010431PentoxifyllinePentoxifylline results in increased expression of MAPK8 protein20804743
D010431PentoxifyllinePentoxifylline results in increased expression of MAPK8 protein modified form20804743
D010457PeptidoglycanPeptidoglycan results in increased phosphorylation of MAPK8 protein21647617
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA20200220
C076994perfluorooctane sulfonic acidsulforafan promotes the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA]20200220
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased phosphorylation of MAPK8 protein28973641
C105905perifosine[perifosine co-treated with Butyrates] results in increased activity of MAPK8 protein15781658
C105905perifosine[perifosine co-treated with trichostatin A] results in increased activity of MAPK8 protein15781658
C105905perifosine[perifosine co-treated with vorinostat] results in increased activity of MAPK8 protein15781658
D030421Peroxynitrous AcidPeroxynitrous Acid results in increased phosphorylation of MAPK8 protein21782928
D015232DinoprostoneDinoprostone results in increased activity of MAPK8 protein16644903
D015232DinoprostoneL-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK8 protein]16644903
C526145Phellinus linteus extract[Doxorubicin co-treated with Phellinus linteus extract] results in increased expression of and results in increased phosphorylation of and results in increased activity of MAPK8 protein16868541
C526145Phellinus linteus extractPhellinus linteus extract results in increased expression of and results in increased phosphorylation of and results in increased activity of MAPK8 protein16868541
D010634PhenobarbitalPhenobarbital affects the expression of MAPK8 mRNA19159669
D010654PhenylbutyratesPhenylbutyrates inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein]18951912
D010656PhenylephrineGLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein]16809552
D010656PhenylephrineMAPK8 protein affects the reaction [Phenylephrine results in decreased expression of KCNIP2 mRNA]16385079
D010656PhenylephrinePhenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein16517124|1680955
D010656PhenylephrinePhenylephrine results in increased phosphorylation of MAPK8 protein10727428|1638507
D010656PhenylephrineRGS2 protein promotes the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein]16517124
C005435phenylmethylpyrazolonephenylmethylpyrazolone results in increased phosphorylation of MAPK8 protein19954754
C005435phenylmethylpyrazolonephenylmethylpyrazolone results in decreased phosphorylation of MAPK8 protein15824197
C018637phorone[phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein20423716
C043103phthalic anhydridephthalic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27129696
C043103phthalic anhydridephthalic anhydride results in increased phosphorylation of MAPK8 protein27129696
C117045p-hydroxycinnamaldehyde"p-hydroxycinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"20933287
C121565pifithrinpifithrin inhibits the reaction [silybin results in increased phosphorylation of MAPK8 protein]16777994
C121565pifithrinpifithrin results in increased phosphorylation of MAPK8 protein16061640
D010862Pilocarpine"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]"19927300
D010862Pilocarpine"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]"19927300
D010862Pilocarpine"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]"19927300
D010862PilocarpinePilocarpine results in increased activity of MAPK8 protein19927300
D010862PilocarpineW 7 inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]19927300
C006253pirinixic acidpirinixic acid results in increased expression of MAPK8 mRNA17426115|1830175
C006253pirinixic acidpirinixic acid results in increased expression of MAPK8 mRNA12832660
D010936Plant Extracts"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]"20206247
D010936Plant ExtractsAscorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]20206247
D010936Plant ExtractsDeferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]20206247
D010936Plant ExtractsPlant Extracts results in increased expression of MAPK8 mRNA23557933
D010936Plant ExtractsPlant Extracts results in increased phosphorylation of MAPK8 protein20206247
D010936Plant Extractspyrazolanthrone inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]20206247
D010936Plant Extracts"Plant Extracts inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]"21537903
D010936Plant ExtractsPlant Extracts inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21465277
D010936Plant ExtractsPlant Extracts results in increased phosphorylation of MAPK8 protein25449124
D010936Plant ExtractsPlant Extracts inhibits the reaction [APP protein alternative form results in increased phosphorylation of MAPK8 protein]16406021
D010936Plant ExtractsPlant Extracts results in decreased expression of MAPK8 mRNA20924750
D028321Plant PreparationsPlant Preparations results in increased expression of MAPK8 mRNA24973489
C098980plitidepsinAKT1 protein affects the reaction [plitidepsin results in increased activity of MAPK8 protein]18089842
C098980plitidepsinplitidepsin results in increased activity of MAPK8 protein18089842
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased phosphorylation of MAPK8 protein23900936
D011092Polyethylene Glycols"[[CAT protein co-treated with Polyethylene Glycols] inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased abundance of Reactive Oxygen Species]] inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21135414
C505150poly(N-vinylpyrrolidine)[[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form27501764
D011134PolysaccharidesPolysaccharides results in increased phosphorylation of MAPK8 protein15894585
D011134Polysaccharides[Polysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK8 protein23831309
D011134PolysaccharidesPolysaccharides inhibits the reaction [Ethanol results in increased phosphorylation of MAPK8 protein]19735724
D011188PotassiumMecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein]18222492
D011188PotassiumPotassium deficiency results in increased phosphorylation of MAPK8 protein18222492
C027373potassium chromate(VI)4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein]10910949
C027373potassium chromate(VI)Hydrogen Peroxide promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein]10910949
C027373potassium chromate(VI)Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein]10910949
C027373potassium chromate(VI)MAP2K7 protein mutant form inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein]10910949
C027373potassium chromate(VI)potassium chromate(VI) results in increased phosphorylation of MAPK8 protein10910949
C061333pramipexolepramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]16362428
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione results in increased activity of MAPK8 protein"17475222
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of MAPK8 mRNA19162173
D044945ProanthocyanidinsProanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of MAPK8 protein]25088297
C479581procyanidin B3Eicosapentaenoic Acid promotes the reaction [[Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein]22169119
C479581procyanidin B3[Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein22169119
C479581procyanidin B3procyanidin B3 promotes the reaction [[Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in decreased phosphorylation of MAPK8 protein]22169119
D011374ProgesteroneProgesterone results in increased expression of MAPK8 mRNA23012394
D011374Progesterone[Estrogens co-treated with Progesterone] results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of MAPK8 protein18486349
D011374ProgesteroneProgesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]16284289
D015237DinoprostDinoprost results in increased phosphorylation of MAPK8 protein24333336
D015237Dinoprostresveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein]24333336
D015237DinoprostSRT1720 inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein]24333336
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]21925238
C107773pterostilbenepterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]19447859
C107773pterostilbenepterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK8 protein24154491
C527556Pt(O,O'-acac)(gamma-acac)(DMS)"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Pt(O,O'-acac)(gamma-acac)(DMS) results in increased phosphorylation of MAPK8 protein]"21420390
C527556Pt(O,O'-acac)(gamma-acac)(DMS)"[Pt(O,O'-acac)(gamma-acac)(DMS) results in increased activity of PRKCD protein] which results in increased phosphorylation of MAPK8 protein"21420390
C527556Pt(O,O'-acac)(gamma-acac)(DMS)"Pt(O,O'-acac)(gamma-acac)(DMS) results in increased phosphorylation of MAPK8 protein"21420390
C034912puag-haadbisindolylmaleimide I inhibits the reaction [puag-haad results in increased expression of MAPK8 mRNA]28780155
C034912puag-haadpuag-haad inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein]18675900
C034912puag-haadpuag-haad results in increased expression of MAPK8 mRNA28780155
C033607puerarinarsenic trioxide promotes the reaction [puerarin results in increased expression of MAPK8 protein]20416161
C033607puerarinpuerarin results in increased expression of MAPK8 protein20416161
C033607puerarinpuerarin results in increased phosphorylation of MAPK8 protein21884717
D011692Puromycin AminonucleosidePuromycin Aminonucleoside binds to and results in increased activity of MAPK8 protein15351692
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]23816505
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]23816505
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK8 protein]15831436
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein]20632440
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK8 protein]22696236
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]18412143|2053473
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein]16041517
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21219922
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK8 protein]15964311
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein]16648635
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [dracorhodin analog results in increased phosphorylation of MAPK8 protein]16864444
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein]16442704
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [LY 293111 results in increased expression of MAPK8 protein modified form]16151469
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]18495191
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased phosphorylation of MAPK8 protein]"20678559
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]20206247
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [resveratrol results in increased phosphorylation of MAPK8 protein]18347188
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [sanguinarine results in increased phosphorylation of MAPK8 protein]19135517
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [silybin results in increased phosphorylation of MAPK8 protein]16777994
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased phosphorylation of MAPK8 protein]15767555
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]18728404
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]14610070
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]15322261
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
C432165pyrazolanthronepyrazolanthrone results in decreased activity of MAPK8 protein12534346|2111266
C432165pyrazolanthronepyrazolanthrone affects the reaction [TALDO1 gene mutant form promotes the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]]19436114
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]19436114
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Acetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein]17185352
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]25531190
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Cadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein]18506790
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased phosphorylation of and results in increased activity of MAPK8 protein]"18840457
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Tretinoin results in increased activity of MAPK8 protein]21626648
C432165pyrazolanthronepyrazolanthrone results in decreased phosphorylation of and results in decreased activity of MAPK8 protein16374168
C432165pyrazolanthronepyrazolanthrone results in decreased phosphorylation of MAPK8 protein16000378
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK8 protein]27174766
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21933187
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]22085843
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]19038359
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK8 protein]21843586
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein]16687388
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Paroxetine results in increased phosphorylation of and results in increased activity of MAPK8 protein]17728140
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein]17651887
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein]17728140
C432165pyrazolanthronepyrazolanthrone results in decreased phosphorylation of MAPK8 protein22085843|2483359
C432165pyrazolanthronepyrazolanthrone results in increased expression of MAPK8 protein16046226
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein]"25530474
C432165pyrazolanthronepyrazolanthrone results in decreased activity of MAPK8 protein16186332|1876633
C020972pyrrolidine dithiocarbamic acidAcetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]22085843
C020972pyrrolidine dithiocarbamic acidbathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein]10941151
C020972pyrrolidine dithiocarbamic acid[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein22085843
C020972pyrrolidine dithiocarbamic acidMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]20920558
C020972pyrrolidine dithiocarbamic acidMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]20920558
C020972pyrrolidine dithiocarbamic acidMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]20920558
C020972pyrrolidine dithiocarbamic acidpyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]22085843
C020972pyrrolidine dithiocarbamic acid[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein10941151
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein10658192
D011765PyruvaldehydePyruvaldehyde results in increased phosphorylation of MAPK8 protein25933243
D011765Pyruvaldehydesulforafan inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein]25933243
D011794Quercetin[Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein15735102
D011794QuercetinHSPA5 protein inhibits the reaction [Quercetin results in increased expression of MAPK8 protein modified form]19017364
D011794QuercetinQuercetin inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]19464278
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]15795422
D011794QuercetinQuercetin inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK8 protein]22592909
D011794QuercetinQuercetin inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]22452660
D011794QuercetinQuercetin results in decreased phosphorylation of and results in decreased activity of MAPK8 protein10718847
D011794QuercetinQuercetin results in increased expression of MAPK8 mRNA23727915
D011794QuercetinQuercetin results in increased expression of MAPK8 protein modified form19017364
D011794QuercetinQuercetin results in increased phosphorylation of MAPK8 protein18377872|2464766
C037219quinolinequinoline analog inhibits the reaction [MAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]]15737997
C037219quinolinequinoline analog results in decreased phosphorylation of and results in decreased activity of MAPK8 protein15737997
D011929RazoxaneRazoxane affects the activity of MAPK810487526
D017382Reactive Oxygen Speciesacetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D017382Reactive Oxygen SpeciesAcetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D017382Reactive Oxygen Species[[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein15173093
D017382Reactive Oxygen Species[[Bortezomib co-treated with vorinostat] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein15173093
D017382Reactive Oxygen Speciesdiphenyleneiodonium inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]21391979
D017382Reactive Oxygen Species[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein21391979
D017382Reactive Oxygen Species"Reactive Oxygen Species affects the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21135414
D017382Reactive Oxygen SpeciesMAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species]17560994
D017382Reactive Oxygen Species"[[CAT protein co-treated with Polyethylene Glycols] inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased abundance of Reactive Oxygen Species]] inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]"21135414
C024353resiniferatoxinresiniferatoxin results in increased activity of MAPK8 protein9580328
C059514resveratrolMAPK8 protein affects the reaction [resveratrol results in increased expression of PRF1 protein]20082299
C059514resveratrolMAPK8 protein affects the susceptibility to resveratrol20082299
C059514resveratrolpyrazolanthrone inhibits the reaction [resveratrol results in increased phosphorylation of MAPK8 protein]18347188
C059514resveratrolresveratrol results in decreased activity of MAPK8 protein11408617
C059514resveratrolresveratrol results in decreased expression of MAPK8 protein18089832
C059514resveratrolresveratrol results in decreased phosphorylation of MAPK8 protein23437203
C059514resveratrolresveratrol results in increased phosphorylation of and results in increased activity of MAPK8 protein15217905|1822242
C059514resveratrolresveratrol results in increased phosphorylation of MAPK8 protein18347188
C059514resveratrolresveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein]16322078
C059514resveratrolresveratrol inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]25956474
C059514resveratrolresveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein]24333336
C059514resveratrolresveratrol inhibits the reaction [Excitatory Amino Acid Agents results in increased phosphorylation of and results in increased activity of MAPK8 protein]20542495
C059514resveratrolresveratrol results in increased activity of MAPK8 protein11933078|2167976
C059514resveratrol[resveratrol results in increased activity of MAPK8 protein] which results in increased phosphorylation of and results in increased activity of TRP53 protein11933078
C059514resveratrol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol results in decreased expression of MAPK8 protein modified form]"27093858
C059514resveratrolresveratrol inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of MAPK8 protein modified form]27093858
C059514resveratrolresveratrol results in decreased expression of MAPK8 protein modified form27093858
C059514resveratrolresveratrol results in decreased phosphorylation of and results in decreased activity of MAPK8 protein10356984
C059514resveratrolMAP3K5 protein promotes the reaction [resveratrol results in increased activity of MAPK8 protein]15217905
C059514resveratrolMAPK8 protein affects the reaction [resveratrol results in increased expression of FASLG protein]15217905
C059514resveratrolMAPK8 protein affects the susceptibility to resveratrol15217905
C089032rimonabant"rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]"18950629
C089032rimonabantrimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein]18950629
C064758Ro 31-8220Ro 31-8220 inhibits the reaction [Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein]11756236
C041376rosmarinic acidrosmarinic acid results in decreased phosphorylation of MAPK8 protein28789951
D012402RotenoneRotenone inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form]17395008
D012402RotenoneRotenone results in increased activity of MAPK8 protein10780954
D012402RotenoneRotenone results in increased phosphorylation of and results in increased activity of MAPK8 protein14976342
D012402RotenoneSLC2A1 protein inhibits the reaction [Rotenone results in increased activity of MAPK8 protein]10780954
D012402RotenoneRotenone results in increased activity of MAPK8 protein11181820
C085746rottlerinrottlerin inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]15917298
C085746rottlerinrottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]20599481
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in decreased expression of MAPK8 mRNA21427059
C036617salsolinolsalsolinol results in increased activity of MAPK8 protein11502874
C496827salubrinalsalubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein]20686688
C496827salubrinalsalubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]21809093
C496827salubrinal[salubrinal results in increased expression of EIF2S1 protein modified form] which results in increased phosphorylation of MAPK8 protein21147958
C018381salvinsalvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein]25446857
C005705sanguinarinepyrazolanthrone inhibits the reaction [sanguinarine results in increased phosphorylation of MAPK8 protein]19135517
C005705sanguinarinesanguinarine results in increased phosphorylation of MAPK8 protein19135517
C044363sappanchalconesappanchalcone results in increased phosphorylation of MAPK8 protein21963806
C093642SB 203580SB 203580 inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK8 protein]15964311
C093642SB 203580SB 203580 inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]13679210
C093642SB 203580SB 203580 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]16818652
C093642SB 203580SB 203580 promotes the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]18495191
C093642SB 203580SB 203580 results in decreased activity of MAPK8 protein18089842
C093642SB 203580SB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein]12487375
C093642SB 203580SB 203580 results in increased phosphorylation of MAPK8 protein28087833
C587178SCH772984SCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK8 protein]28087833
C587178SCH772984SCH772984 results in decreased expression of MAPK8 protein28087833
C499748SCIO-469SCIO-469 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]16818652
D012643SeleniumSelenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26187450
D012643SeleniumSelenium results in decreased expression of MAPK8 mRNA28810182
D012643SeleniumSelenium results in decreased phosphorylation of MAPK8 protein17997286
D012643SeleniumSelenium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]17383151
D012645SelenomethionineSelenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein]20121705
D017632Asbestos, Serpentine"Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein]"24735948
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein"15882436|2473594
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein"25530474
D017632Asbestos, Serpentine"pyrazolanthrone inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein]"25530474
D020280Sertralinepyrazolanthrone inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein]17728140
D020280SertralineSertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein17728140
D017640SilicatesSilicates results in increased phosphorylation of and results in increased activity of MAPK8 protein11280724
D012822Silicon DioxideSilicon Dioxide analog results in increased phosphorylation of MAPK8 protein24844442
D012822Silicon DioxideSilicon Dioxide results in increased phosphorylation of MAPK8 protein26163174
D012822Silicon DioxideSilicon Dioxide results in decreased expression of MAPK8 mRNA19073995
D012822Silicon DioxideSilicon Dioxide results in increased phosphorylation of MAPK8 protein27616297
D012834SilverSilver affects the expression of MAPK8 mRNA22342292
D012834SilverSilver results in increased phosphorylation of MAPK8 protein26702581
C440975silybinpifithrin inhibits the reaction [silybin results in increased phosphorylation of MAPK8 protein]16777994
C440975silybinpyrazolanthrone inhibits the reaction [silybin results in increased phosphorylation of MAPK8 protein]16777994
C440975silybinsilybin results in increased phosphorylation of MAPK8 protein16777994
D012838SilymarinSilymarin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]16728380
D012838SilymarinSilymarin inhibits the reaction [Cadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein]16728380
D012838SilymarinSilymarin results in increased expression of MAPK8 mRNA26335259
D019821Simvastatinfarnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]]18310456
D019821SimvastatinSimvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]18310456
D019821SimvastatinSimvastatin results in increased activity of MAPK8 protein15187114
D019821SimvastatinSimvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]18047562
D020123Sirolimus[7-hydroxystaurosporine co-treated with Sirolimus] results in increased phosphorylation of MAPK8 protein15767555
D020123Sirolimuspyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased phosphorylation of MAPK8 protein]15767555
C009277sodium arsenatesodium arsenate results in increased phosphorylation of MAPK8 protein12221076
C017947sodium arseniteMAPK8 mutant form inhibits the reaction [sodium arsenite results in increased expression of ELK1 mRNA]21642427
C017947sodium arseniteMAPK8 protein affects the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]26291278
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased expression of CCND1 protein]21726611
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased expression of CDK4 protein]21726611
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased phosphorylation of RB1 protein]21726611
C017947sodium arseniteMAPK8 protein results in increased susceptibility to sodium arsenite21726611
C017947sodium arsenitesodium arsenite promotes the reaction [MAPK8 protein binds to MAPK9 protein binds to TP53 protein modified form]22706169
C017947sodium arsenitesodium arsenite results in increased activity of MAPK8 protein22706169|2321984
C017947sodium arsenitesodium arsenite results in increased expression of MAPK8 protein modified form23219847
C017947sodium arsenitesodium arsenite results in increased phosphorylation of MAPK8 protein12482858|1915440
C017947sodium arsenitetetramethylpyrazine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]26404762
C017947sodium arseniteCDKN1B protein affects the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]20566634
C017947sodium arsenite"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK8 mRNA]"28757890
C017947sodium arsenite"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK8 protein modified form]"28757890
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased activity of CASP3 protein]16973625
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased cleavage of PARP1 protein]16973625
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased expression of GADD45A mRNA]16973625
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased expression of GADD45A protein]16973625
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of JUN protein]16973625
C017947sodium arsenitesodium arsenite results in increased expression of MAPK8 mRNA19822182|2875789
C017947sodium arsenitesodium arsenite results in increased expression of MAPK8 protein9671412
C017947sodium arsenitesodium arsenite results in increased expression of MAPK8 protein modified form28757890
C017947sodium arsenitesodium arsenite results in increased phosphorylation of and results in increased activity of MAPK8 protein23143138
C017947sodium arsenitesodium arsenite results in increased phosphorylation of MAPK8 protein16973625|1899635
C017947sodium arsenite2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein]20829427
C017947sodium arsenite[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein20829427
C017947sodium arseniteCurcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]24952339
C017947sodium arseniteMAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency]11312036
C017947sodium arsenite"O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [sodium arsenite results in increased activity of MAPK8 protein]"17658681
C017947sodium arsenitesodium arsenite results in decreased expression of MAPK8 protein19072884
C017947sodium arsenitesodium arsenite results in increased activity of MAPK8 protein17658681
C017947sodium arsenitesodium arsenite results in increased expression of MAPK8 mRNA24497207
C017947sodium arsenitesodium arsenite results in increased phosphorylation of MAPK8 protein11408547|2162152
C017947sodium arsenitetrans-3-(4'-hydroxyphenyl)-2-propenoic acid inhibits the reaction [sodium arsenite results in increased expression of MAPK8 mRNA]24497207
C017947sodium arseniteVinyl Compounds analog inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]21621526
C016104sodium bichromateMAPK8 protein affects the reaction [sodium bichromate results in increased cleavage of BID protein]21047991
C016104sodium bichromateMAPK8 protein affects the reaction [sodium bichromate results in increased expression of CASP3 protein modified form]21047991
C016104sodium bichromateMAPK8 protein affects the reaction [sodium bichromate results in increased expression of JUN protein]21047991
C016104sodium bichromateMAPK8 protein affects the reaction [sodium bichromate results in increased expression of JUN protein modified form]21047991
C016104sodium bichromateMAPK8 protein affects the reaction [sodium bichromate results in increased expression of TRP53 protein modified form]21047991
C016104sodium bichromateMAPK8 protein affects the susceptibility to sodium bichromate21047991
C016104sodium bichromatesodium bichromate results in increased phosphorylation of and results in increased activity of MAPK8 protein21047991
C016104sodium bichromatesodium bichromate affects the expression of MAPK8 mRNA11960910
C016104sodium bichromateCAT protein inhibits the reaction [sodium bichromate results in increased phosphorylation of and results in increased activity of MAPK8 protein]21047991
D012965Sodium ChlorideAcetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]23816505
D012965Sodium ChlorideGlutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]23816505
D012965Sodium Chloridepyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]23816505
D012965Sodium ChlorideSodium Chloride results in increased phosphorylation of MAPK8 protein23816505
D018038Sodium SeleniteAcetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]18728404
D018038Sodium SeleniteDithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein]10644709
D018038Sodium SeleniteMAPK8 protein affects the reaction [Sodium Selenite results in decreased activity of JUN protein]10644709
D018038Sodium SeleniteMercaptoethanol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein]10644709
D018038Sodium Selenitepyrazolanthrone inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]18728404
D018038Sodium SeleniteSodium Selenite results in decreased activity of MAPK8 protein10644709
D018038Sodium SeleniteSodium Selenite results in decreased expression of MAPK8 mRNA18175754
D018038Sodium SeleniteSodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein18728404
D018038Sodium SeleniteSodium Selenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein]18481333
D018038Sodium SeleniteSodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]26522834
D012999Soman[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein]21971501
D012999SomanSoman results in increased phosphorylation of MAPK8 protein21971501
D053260SootSoot results in increased phosphorylation of MAPK8 protein19782127
C471405sorafenib[Bortezomib co-treated with sorafenib] results in increased phosphorylation of MAPK8 protein16985072
C551307soyasaponin Absoyasaponin Ab inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]22060784
D013096SpermineAcetylcysteine inhibits the reaction [Spermine results in increased activity of MAPK8 protein]20121705
D013096SpermineSelenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein]20121705
D013096SpermineSpermine results in increased activity of MAPK8 protein20121705
C110630SR 144528SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK8 protein]24184660
C525422SRT1720SRT1720 inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein]24333336
D019311StaurosporineStaurosporine binds to MAPK8 protein21815634
D013311StreptozocinStreptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]25541468
D013311StreptozocinSodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]26522834
D013311Streptozocin[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein26522834
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of MAPK8 mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of MAPK8 mRNA26378955
C016766sulforafansulforafan promotes the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA]20200220
C016766sulforafansulforafan inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein]25933243
C016766sulforafansulforafan results in increased activity of MAPK8 protein16201852
D013467SulindacCDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein]17292881
D013467SulindacMAPK8 affects the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]18281123
D013467SulindacSulindac promotes the reaction [IL24 protein results in increased phosphorylation of MAPK8 protein]15713900
D013467SulindacSulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein17292881
D013467SulindacSulindac results in increased phosphorylation of and results in increased activity of MAPK8 protein15713900
D013467SulindacSulindac results in increased expression of MAPK8 mRNA17292881
D013467SulindacSulindac results in increased phosphorylation of MAPK8 protein17292881
C025462sulindac sulfidesulindac sulfide results in increased activity of MAPK8 protein11051267
C025463sulindac sulfonesulindac sulfone results in increased activity of MAPK8 protein11051267|1127826
D016559TacrolimusTacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]12892836
D016559TacrolimusTacrolimus results in decreased activity of MAPK8 protein12892836
D013629Tamoxifenalpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein]14645110
D013629TamoxifenTamoxifen results in increased activity of MAPK8 protein14645110
D013629TamoxifenTamoxifen inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein]23038002
D013629TamoxifenTamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein]23038002
D013654Taurine[Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased expression of MAPK8 mRNA]26335259
D013654Taurine[Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]26335259
D013654Taurine[[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form27501764
D013654Taurine[Taurine binds to Zinc] which results in decreased expression of MAPK8 mRNA26335259
D013654Taurine[Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form27501764
D013654TaurineTaurine inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]26335259
D013654TaurineTaurine results in decreased expression of MAPK8 protein modified form27501764
D013656Taurocholic AcidNR1H4 gene mutant form promotes the reaction [Taurocholic Acid results in increased phosphorylation of MAPK8 protein]28505368
C003377taxifolintaxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein]12044887
D000068698TenofovirTenofovir affects the phosphorylation of MAPK8 protein27041070
C045037testosterone-3-carboxymethyloxime-bovine serum albumin conjugatetestosterone-3-carboxymethyloxime-bovine serum albumin conjugate affects the expression of MAPK8 mRNA20189893
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased phosphorylation of MAPK8 protein16198432
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of MAPK8 mRNA28970181
D013748Tetracaine"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]"11981161
D013748Tetracaine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]11981161
D013748TetracaineCurcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]11981161
D013748TetracaineEgtazic Acid inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]11981161
D013748TetracaineTetracaine results in increased phosphorylation of MAPK8 protein11981161
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased phosphorylation of MAPK8 protein27393035
D013749TetrachlorodibenzodioxinMAPK8 affects the susceptibility to Tetrachlorodibenzodioxin9677421
D013749TetrachlorodibenzodioxinMAPK8 results in increased susceptibility to Tetrachlorodibenzodioxin9677421
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK8 protein16619036
D013749TetrachlorodibenzodioxinMAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of INSR protein]20181658
D013749TetrachlorodibenzodioxinMAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of IRS1 protein]20181658
D013749TetrachlorodibenzodioxinMAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A4 protein]20181658
D013749TetrachlorodibenzodioxinMAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF protein]20181658
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of MAPK8 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of MAPK8 mRNA19465110
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of MAPK8 protein20181658
D013755Tetradecanoylphorbol AcetateCBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]25818598
D013755Tetradecanoylphorbol Acetatefulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA]21331654
D013755Tetradecanoylphorbol Acetatepterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]19447859
D013755Tetradecanoylphorbol Acetatepyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]14610070
D013755Tetradecanoylphorbol Acetaterottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]20599481
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA21331654
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]14610070
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein16838270|1944785
D013755Tetradecanoylphorbol AcetateChenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]25496033
D013755Tetradecanoylphorbol AcetateGW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]25496033
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein20172950|2038160
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MAPK8 mRNA25613284
C017953tetramethylpyrazinetetramethylpyrazine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]26404762
D019284ThapsigarginThapsigargin results in increased phosphorylation of MAPK8 protein21147958
C572247thiamet Gthiamet G promotes the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein]29325178
D013849ThimerosalThimerosal results in increased expression of MAPK8 mRNA27188386
D013849ThimerosalThimerosal results in increased phosphorylation of MAPK8 protein18495191
D013853ThioacetamideThioacetamide results in increased expression of MAPK8 mRNA16456712
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA23830814
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK8 mRNA23830814
D008063Thioctic Acid[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA23830814
C009495titanium dioxidetitanium dioxide results in increased expression of MAPK8 mRNA22342292
C009495titanium dioxidetitanium dioxide results in increased expression of MAPK8 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of MAPK8 mRNA20133372
C479163tofacitinibtofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of MAPK8 protein]21548952
C495469trans-3-(4'-hydroxyphenyl)-2-propenoic acidtrans-3-(4'-hydroxyphenyl)-2-propenoic acid inhibits the reaction [sodium arsenite results in increased expression of MAPK8 mRNA]24497207
D014212Tretinoinpyrazolanthrone inhibits the reaction [Tretinoin results in increased activity of MAPK8 protein]21626648
D014212TretinoinSPAG9 protein promotes the reaction [Tretinoin results in increased phosphorylation of MAPK8 protein]16619266
D014212TretinoinTretinoin results in decreased expression of MAPK8 mRNA22498432
D014212TretinoinTretinoin results in decreased phosphorylation of MAPK8 protein16084493
D014212TretinoinTretinoin results in increased activity of MAPK8 protein21626648
D014212TretinoinTretinoin results in increased phosphorylation of MAPK8 protein16619266
D014212TretinoinTretinoin results in increased expression of MAPK8 protein15961395
C011559tributyltintributyltin results in increased phosphorylation of MAPK8 protein21626652
C447082tricarbonyldichlororuthenium (II) dimer1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
C447082tricarbonyldichlororuthenium (II) dimer2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
C447082tricarbonyldichlororuthenium (II) dimer"6,7-dimethoxy-3-phenylquinoxaline inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]"26385185
C447082tricarbonyldichlororuthenium (II) dimerMAPK8 protein promotes the reaction [tricarbonyldichlororuthenium (II) dimer results in increased expression of HMOX1 protein]26385185
C447082tricarbonyldichlororuthenium (II) dimerProtein Kinase Inhibitors inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
C447082tricarbonyldichlororuthenium (II) dimerpyrazolanthrone inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]26385185
C447082tricarbonyldichlororuthenium (II) dimertricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein26385185
C012589trichostatin ADUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]]21911040
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA"27188386
C012589trichostatin A[perifosine co-treated with trichostatin A] results in increased activity of MAPK8 protein15781658
C012589trichostatin Atrichostatin A affects the expression of MAPK8 mRNA28542535
C012589trichostatin Atrichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]21911040
C012589trichostatin Atrichostatin A results in decreased expression of MAPK8 mRNA22723015|2627250
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein]21544200
C015559trimellitic anhydridetrimellitic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]27129696
C015559trimellitic anhydridetrimellitic anhydride results in increased phosphorylation of MAPK8 protein27129696
C052920trimethylarsine oxidetrimethylarsine oxide results in decreased expression of MAPK8 mRNA17481689
C046488trimethyltinmagnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein]26756313
C046488trimethyltintrimethyltin results in increased phosphorylation of MAPK8 protein26756313
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA23537331
D010853Picryl ChloridePicryl Chloride results in increased phosphorylation of MAPK8 protein20381601
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of MAPK8 mRNA"26179874
C057693troglitazonetroglitazone results in increased phosphorylation of and results in increased activity of MAPK8 protein15064713
C057693troglitazonetroglitazone results in decreased expression of MAPK8 mRNA28973697
D014415TunicamycinTunicamycin results in increased expression of MAPK8 mRNA17127020
D014415TunicamycinTunicamycin results in increased phosphorylation of MAPK8 protein21147958
C406122tyrphostin A9tyrphostin A9 inhibits the reaction [S100A4 protein results in increased phosphorylation of MAPK8 protein]16948116
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein]11329622
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]26514923
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein]15574683
C113580U 0126"U 0126 inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK8 protein]"28087840
C113580U 0126U 0126 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK8 protein]28087833
D014502Uranyl NitrateUranyl Nitrate results in increased phosphorylation of MAPK8 protein26529667
D014520UrethaneUrethane results in increased expression of MAPK8 mRNA28818685
C005466ursolic acid"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]]"27274199
C005466ursolic acidursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]27274199
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of MAPK8 mRNA23179753|2493525
D014635Valproic AcidValproic Acid results in increased expression of MAPK8 mRNA25716160
D014635Valproic AcidValproic Acid results in decreased expression of MAPK8 mRNA21427059
D014635Valproic AcidValproic Acid results in increased phosphorylation of MAPK8 protein23378038
D001335Vehicle EmissionsVehicle Emissions results in increased phosphorylation of MAPK8 protein23900936
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of MAPK8 gene25560391
D001335Vehicle EmissionsVehicle Emissions results in increased phosphorylation of MAPK8 protein17240030
D001335Vehicle EmissionsVehicle Emissions results in increased expression of MAPK8 mRNA24216475
D014700VerapamilVerapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein]15936777
C573672VI-14 flavonoidVI-14 flavonoid results in decreased phosphorylation of and results in decreased activity of MAPK8 protein22538171
D014747VinblastineTP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]12221076
D014747VinblastineVinblastine results in increased phosphorylation of MAPK8 protein12221076
D014753Vinyl CompoundsVinyl Compounds analog inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]21621526
D014800VitalliumVitallium analog results in decreased expression of MAPK8 mRNA23825117
D009536NiacinamideNiacinamide inhibits the reaction [Methylnitrosourea results in increased phosphorylation of MAPK8 protein]16168987
D014810Vitamin EVitamin E results in decreased expression of MAPK8 mRNA19244175
D014810Vitamin EVitamin E results in increased activity of MAPK8 protein11522656
D024483Vitamin K 3MAPK8 protein affects the susceptibility to Vitamin K 312215205
D024483Vitamin K 3Vitamin K 3 results in increased activity of MAPK8 protein12215205
D024483Vitamin K 3Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK8 protein19386027
D024483Vitamin K 3Vitamin K 3 results in increased phosphorylation of MAPK8 protein16310883
D024483Vitamin K 3Vitamin K 3 results in increased phosphorylation of MAPK8 protein18086661
C111237vorinostat[3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein15964800
C111237vorinostatAcetylcysteine inhibits the reaction [[Bortezomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein]15173093
C111237vorinostat[[Bortezomib co-treated with vorinostat] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein15173093
C111237vorinostat[Bortezomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein12893773|1517309
C111237vorinostat[perifosine co-treated with vorinostat] results in increased activity of MAPK8 protein15781658
C111237vorinostat[carfilzomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein20233973
C017967W 7W 7 inhibits the reaction [Pilocarpine results in increased activity of MAPK8 protein]19927300
C521629Wen-pi-tang-Hab-Wu-ling-sanWen-pi-tang-Hab-Wu-ling-san results in decreased phosphorylation of MAPK8 protein18570213
C113888WHI P154"WHI P154 inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of MAPK8 protein]"16778083
C070417Win 55212-2Win 55212-2 results in increased phosphorylation of MAPK8 protein20619260
C009684withaferin Awithaferin A results in increased phosphorylation of MAPK8 protein21964475
C085514wogoninwogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK8 protein]23362215
C009687wortmannin"wortmannin inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]"18950629
C009687wortmanninwortmannin inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein]18950629
C009687wortmanninwortmannin results in decreased phosphorylation of MAPK8 protein18950629
C066632yessotoxinyessotoxin results in increased activity of MAPK8 protein21945047
D015215ZidovudineZidovudine results in increased phosphorylation of MAPK8 protein27041070
D015032Zinc[Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein16648635
D015032ZincZinc results in increased phosphorylation of MAPK8 protein16606632
D015032Zinc[Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased expression of MAPK8 mRNA]26335259
D015032Zinc[Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein]26335259
D015032Zinc[[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form27501764
D015032Zinc[Taurine binds to Zinc] which results in decreased expression of MAPK8 mRNA26335259
D019345Zinc Acetate[Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form27501764
C016837zinc chloride2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]11306679
C016837zinc chlorideAcetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]11306679
C016837zinc chloridePIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]11306679
C016837zinc chlorideRAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]11306679
C016837zinc chloridezinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]20423716
C016837zinc chloridezinc chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein11306679
D019287Zinc SulfateZinc Sulfate results in increased phosphorylation of MAPK8 protein16606632
C031238zinc sulfide[cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK8 mRNA22342292
C000588918ziyuglycoside IIMAPK8 mutant form inhibits the reaction [ziyuglycoside II results in decreased expression of BCL2 protein]24680927
C000588918ziyuglycoside IIMAPK8 mutant form inhibits the reaction [ziyuglycoside II results in increased expression of BAX protein]24680927
C000588918ziyuglycoside IIMAPK8 mutant form inhibits the reaction [ziyuglycoside II results in increased expression of FASLG protein]24680927
C000588918ziyuglycoside IIMAPK8 mutant form inhibits the reaction [ziyuglycoside II results in increased expression of FAS protein]24680927
C088658zoledronic acidzoledronic acid promotes the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]17059425
D015054ZymosanDexamethasone inhibits the reaction [Zymosan results in increased phosphorylation of and results in increased activity of MAPK8 protein]10874129
D015054ZymosanZymosan results in increased phosphorylation of and results in increased activity of MAPK8 protein10874129

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004674protein serine/threonine kinase activity-IDA14967141  15850461  20027304  21095239  
GO:0004705JUN kinase activity-IDA8654373  21095239  
GO:0004705JUN kinase activity-TAS-  
GO:0004707MAP kinase activity-IBA21873635  
GO:0005515protein binding-IPI10393177  10490659  10747973  10856240  11517249  15334056  
15733859  15894542  16291755  16533805  16840345  16982329  
18003900  18286207  19234442  19527717  23397142  25241761  
25284480  27043084  
GO:0005524ATP binding-IEA-  
GO:0016301kinase activity-TAS-  
GO:0019899enzyme binding-IPI14615289  
GO:0035033histone deacetylase regulator activity-IMP20027304  
GO:0042826histone deacetylase binding-IPI20027304  
GO ID GO Term Qualifier Evidence PubMed
GO:0006468protein phosphorylation-IDA21856198  
GO:0006468protein phosphorylation-IMP22441692  
GO:0007254JNK cascade-IDA8654373  
GO:0007254JNK cascade-TAS-  
GO:0007258JUN phosphorylation-IDA14967141  21095239  
GO:0009411response to UV-IDA14967141  
GO:0009612response to mechanical stimulus-IBA21873635  
GO:0010468regulation of gene expression-IBA21873635  
GO:0010628positive regulation of gene expression-IMP22065586  
GO:0016241regulation of macroautophagy-TAS26546165  
GO:0018105peptidyl-serine phosphorylation-IDA15850461  20027304  21095239  
GO:0018107peptidyl-threonine phosphorylation-IDA21095239  
GO:0018107peptidyl-threonine phosphorylation-IMP20027304  
GO:0031063regulation of histone deacetylation-IEA-  
GO:0031281positive regulation of cyclase activity-IMP22027397  
GO:0032091negative regulation of protein binding-IDA21095239  
GO:0032880regulation of protein localization-IDA20027304  
GO:0034198cellular response to amino acid starvation-IDA11096076  
GO:0034614cellular response to reactive oxygen species-IMP26514923  
GO:0035556intracellular signal transduction-IBA21873635  
GO:0038095Fc-epsilon receptor signaling pathway-TAS-  
GO:0042752regulation of circadian rhythm-ISS-  
GO:0043065positive regulation of apoptotic process-IBA21873635  
GO:0043065positive regulation of apoptotic process-TAS-  
GO:0043066negative regulation of apoptotic process-IDA14967141  21095239  
GO:0048511rhythmic process-IEA-  
GO:0048666neuron development-IBA21873635  
GO:0051247positive regulation of protein metabolic process-IMP22027397  
GO:0051403stress-activated MAPK cascade-IDA11096076  
GO:0071222cellular response to lipopolysaccharide-IDA23776175  
GO:0071260cellular response to mechanical stimulus-IEP19593445  
GO:0071276cellular response to cadmium ion-IMP26514923  
GO:0071310cellular response to organic substance-IBA21873635  
GO:0071345cellular response to cytokine stimulus-TAS-  
GO:0090045positive regulation of deacetylase activity-IMP20027304  
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-TAS-  
GO:1902595regulation of DNA replication origin binding-IMP21856198  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA20027304  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IBA21873635  
GO:0005739mitochondrion-IEA-  
GO:0005829cytosol-TAS-  
GO:0030424axon-ISS22683681  
GO:0043005neuron projection-IBA21873635  
GO:0097441basal dendrite-ISS22683681  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04012ErbB signaling pathway
hsa04141Protein processing in endoplasmic reticulum
hsa04310Wnt signaling pathway
hsa04380Osteoclast differentiation
hsa04510Focal adhesion
hsa04620Toll-like receptor signaling pathway
hsa04621NOD-like receptor signaling pathway
hsa04622RIG-I-like receptor signaling pathway
hsa04664Fc epsilon RI signaling pathway
hsa04722Neurotrophin signaling pathway
hsa04910Insulin signaling pathway
hsa04912GnRH signaling pathway
hsa04914Progesterone-mediated oocyte maturation
hsa04920Adipocytokine signaling pathway
hsa04930Type II diabetes mellitus
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa05131Shigellosis
hsa05142Chagas disease (American trypanosomiasis)
hsa05145Toxoplasmosis
hsa05160Hepatitis C
hsa05200Pathways in cancer
hsa05210Colorectal cancer
hsa05212Pancreatic cancer
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111446Activation of BIM and translocation to mitochondria TAS
R-HSA-114452Activation of BH3-only proteinsTAS
R-HSA-1266738Developmental BiologyTAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-139910Activation of BMF and translocation to mitochondriaTAS
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-166016Toll Like Receptor 4 (TLR4) CascadeTAS
R-HSA-166058MyD88:Mal cascade initiated on plasma membraneTAS
R-HSA-166166MyD88-independent TLR4 cascade TAS
R-HSA-168138Toll Like Receptor 9 (TLR9) CascadeTAS
R-HSA-168142Toll Like Receptor 10 (TLR10) CascadeTAS
R-HSA-168164Toll Like Receptor 3 (TLR3) CascadeTAS
R-HSA-168176Toll Like Receptor 5 (TLR5) CascadeTAS
R-HSA-168179Toll Like Receptor TLR1:TLR2 CascadeTAS
R-HSA-168181Toll Like Receptor 7/8 (TLR7/8) CascadeTAS
R-HSA-168188Toll Like Receptor TLR6:TLR2 CascadeTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-168898Toll-Like Receptors CascadesTAS
R-HSA-181438Toll Like Receptor 2 (TLR2) CascadeTAS
R-HSA-193648NRAGE signals death through JNKTAS
R-HSA-193648NRAGE signals death through JNKIEA
R-HSA-193704p75 NTR receptor-mediated signallingTAS
R-HSA-193704p75 NTR receptor-mediated signallingIEA
R-HSA-204998Cell death signalling via NRAGE, NRIF and NADETAS
R-HSA-204998Cell death signalling via NRAGE, NRIF and NADEIEA
R-HSA-205043NRIF signals cell death from the nucleusIEA
R-HSA-2262752Cellular responses to stressTAS
R-HSA-2454202Fc epsilon receptor (FCERI) signalingTAS
R-HSA-2559580Oxidative Stress Induced SenescenceTAS
R-HSA-2559583Cellular SenescenceTAS
R-HSA-2871796FCERI mediated MAPK activationTAS
R-HSA-373752Netrin-1 signalingTAS
R-HSA-376172DSCAM interactionsTAS
R-HSA-422475Axon guidanceTAS
R-HSA-446652Interleukin-1 family signalingTAS
R-HSA-448424Interleukin-17 signalingTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-450282MAPK targets/ Nuclear events mediated by MAP kinasesTAS
R-HSA-450294MAP kinase activationTAS
R-HSA-450321JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1TAS
R-HSA-450341Activation of the AP-1 family of transcription factorsTAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5693532DNA Double-Strand Break RepairTAS
R-HSA-5693565Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaksTAS
R-HSA-5693606DNA Double Strand Break ResponseTAS
R-HSA-73887Death Receptor SignallingTAS
R-HSA-73887Death Receptor SignallingIEA
R-HSA-73894DNA RepairTAS
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-9007892Interleukin-38 signalingTAS
R-HSA-937061TRIF(TICAM1)-mediated TLR4 signaling TAS
R-HSA-975138TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activationTAS
R-HSA-975155MyD88 dependent cascade initiated on endosomeTAS
R-HSA-975871MyD88 cascade initiated on plasma membraneTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
19661247Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production. (2009 Nov 1)Deshmukh HSAm J Respir Crit Care Med
20422711Benzo(a)pyrene causes PRKAA1/2-dependent ID2 loss in trophoblast stem cells. (2010 Jun)Xie YMol Reprod Dev
25629224MAPK genes interact with diet and lifestyle factors to alter risk of breast cancer: the Breast Cancer Health Disparities Study. (2015)Slattery MLNutr Cancer
23027623MAP kinase genes and colon and rectal cancer. (2012 Dec)Slattery MLCarcinogenesis
28592245In silico identification of potential key regulatory factors in smoking-induced lung cancer. (2017 Jun 7)El-Aarag SABMC Med Genomics
22199996Tumor necrosis factor-related genes and colon and rectal cancer. (2011)Slattery MLInt J Mol Epidemiol Genet