Gene: ANKRD7

56311
TSA806
ankyrin repeat domain 7
protein-coding
7q31.31
Ensembl:ENSG00000106013 MIM:610731 Vega:OTTHUMG00000156960 UniprotKB:Q92527
NC_000007.14
PubMed
0   ANCO-SNPs
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.634e-1 (AD)  6.417e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF4490.604
SLC36A40.603
PPIP5K20.59
TXNDC90.589
NDC10.589
HACL10.578
SLC37A30.575
ANKRD500.575
TENM10.574
TRPC10.574

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FOXJ1-0.39
EYA2-0.373
FAM151A-0.358
EMX2-0.352
NWD1-0.346
PLIN4-0.34
WDR38-0.327
RFX2-0.317
EVC2-0.311
ACOX2-0.31

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of ANKRD7 mRNA21298039
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of ANKRD7 mRNA24449571
C006780bisphenol Abisphenol A results in decreased expression of ANKRD7 mRNA25181051
D005485FlutamideFlutamide results in increased expression of ANKRD7 mRNA24793618
D004397FonofosFonofos results in increased methylation of ANKRD7 promoter22847954
D010278ParathionParathion results in increased methylation of ANKRD7 promoter22847954
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of ANKRD7 mRNA25895662
C012568terbufosterbufos results in increased methylation of ANKRD7 promoter22847954
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of ANKRD7 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0008584male gonad development-TAS8812458  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
22613542ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. (2012 Mar)Chen XDChin Med J (Engl)