Gene: PSG2

5670
CEA|PSBG2|PSG1
pregnancy specific beta-1-glycoprotein 2
protein-coding
19q13.31
Ensembl:ENSG00000242221 MIM:176391 Vega:OTTHUMG00000151547 UniprotKB:P11465
NC_000019.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.721e-1 (AD)  1.384e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4C160.873
OR5L10.828
OR5AS10.817
OR4L10.814
C4orf170.814
OR4C50.813
OR2W10.81
TMCO5A0.805
KRTAP27-10.804
OR4C120.804

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DBP-0.315
ASPDH-0.305
ZNF835-0.304
FAM43B-0.3
NOG-0.3
FUT9-0.295
BGLAP-0.293
TMEM221-0.291
CYP46A1-0.291
C16orf95-0.288

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of PSG2 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of PSG2 mRNA27153756
D002857ChromiumChromium results in increased expression of PSG2 mRNA21437242
D016572CyclosporineCyclosporine results in decreased expression of PSG2 mRNA27989131
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of PSG2 mRNA22714537

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003674molecular_function-ND-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007565female pregnancy-NAS3260773  
GO:0016477cell migration-NAS3260773  
GO ID GO Term Qualifier Evidence PubMed
GO:0005575cellular_component-ND-  
GO:0005576extracellular region-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-202733Cell surface interactions at the vascular wallTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24419231Axonal guidance signaling pathway interacting with smoking in modifying the risk of pancreatic cancer: a gene- and pathway-based interaction analysis of GWAS data. (2014 May)Tang HCarcinogenesis