Gene: SLC2A4RG

56731
GEF|HDBP-1|HDBP1|Si-1-2|Si-1-2-19
SLC2A4 regulator
protein-coding
20q13.33
Ensembl:ENSG00000125520 MIM:609493 Vega:OTTHUMG00000032997 UniprotKB:Q9NR83
NG_046992.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.211e-1 (AD)  7.259e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
COMT0.866
SZRD10.856
SORBS30.852
NECAP20.848
DDAH20.846
TRIP60.831
TP53I130.83
SLC25A10.83
EFEMP20.822
DDR10.819

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.518
OR4F29-0.514
TYRP1-0.478
IL1RAPL2-0.458
GABRG3-0.452
CDH7-0.446
NXPH2-0.441
AGMAT-0.435
COL19A1-0.433
PCDHAC1-0.423

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC2A4RG mRNA"19167446
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of SLC2A4RG mRNA24449571
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SLC2A4RG mRNA20106945|2623829
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SLC2A4RG mRNA28628672
C584509C646 compoundC646 compound results in increased expression of SLC2A4RG mRNA26191083
C018021cobaltous chloridecobaltous chloride results in decreased expression of SLC2A4RG mRNA19376846
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of SLC2A4RG mRNA20971185
D019327Copper SulfateCopper Sulfate results in decreased expression of SLC2A4RG mRNA19549813
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC2A4RG mRNA"19167446
D003375CoumestrolCoumestrol results in increased expression of SLC2A4RG mRNA19167446
D016572CyclosporineCyclosporine results in decreased expression of SLC2A4RG mRNA20106945|2556210
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SLC2A4RG mRNA28628672
D003976DiazinonDiazinon results in increased methylation of SLC2A4RG gene22964155
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of SLC2A4RG mRNA20044591
C492448ICG 001ICG 001 results in increased expression of SLC2A4RG mRNA26191083
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SLC2A4RG mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SLC2A4RG mRNA28628672
C544151jinfukangjinfukang results in increased expression of SLC2A4RG mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of SLC2A4RG mRNA23086925
C410337K 7174K 7174 results in decreased expression of SLC2A4RG mRNA24086573
D007854LeadLead results in increased expression of SLC2A4RG mRNA19921347
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of SLC2A4RG mRNA20971185
C558013NSC 689534NSC 689534 results in decreased expression of SLC2A4RG mRNA20971185
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of SLC2A4RG mRNA17097637
D010936Plant ExtractsPlant Extracts results in decreased expression of SLC2A4RG mRNA24677778
C061133tamibarotenetamibarotene results in increased expression of SLC2A4RG mRNA17229644
D014212TretinoinTretinoin results in increased expression of SLC2A4RG mRNA23724009
C057693troglitazonetroglitazone results in decreased expression of SLC2A4RG mRNA19140230
D014635Valproic AcidValproic Acid results in decreased expression of SLC2A4RG mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of SLC2A4RG mRNA23179753
D024483Vitamin K 3Vitamin K 3 affects the expression of SLC2A4RG mRNA20044591

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003700DNA-binding transcription factor activity-TAS10825161  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006355regulation of transcription, DNA-templated-TAS10825161  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-NAS10825161  
GO:0005737cytoplasm-IEA-  
GO:0016607nuclear speck-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29456763Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study. (2018)Li SClin Epigenetics