Gene: BAD

572
BBC2|BCL2L8
BCL2 associated agonist of cell death
protein-coding
11q13.1
Ensembl:ENSG00000002330 MIM:603167 Vega:OTTHUMG00000134302 UniprotKB:Q92934
NC_000011.10
PubMed
CD|OD|ND|AD
120   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.871e-1 (AD)  3.035e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RPS19BP10.946
CCDC1240.943
DGCR6L0.935
AURKAIP10.935
NDUFB70.925
NUBP20.92
ANAPC110.92
TIMM130.919
SSNA10.918
NDUFS80.917

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.771
OR4F29-0.747
SFTPA1-0.303
TECRL-0.302
KCNJ15-0.296
STEAP4-0.291
VNN2-0.291
SFTPB-0.291
CD160-0.288
TBX4-0.287

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB12340NavitoclaxSmall Molecule923564-51-6InvestigationalTarget
ID Drug Name Action PubMed
C47167410'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone"10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone results in increased expression of BAD mRNA"23088786
D0140131,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of BAD protein]"22915474
C0374131,3-dinitropyrene"1,3-dinitropyrene results in decreased phosphorylation of BAD protein"17240030
C0374131,3-dinitropyrene"1,3-dinitropyrene results in increased phosphorylation of BAD protein"17240030
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of BAD mRNA"28903501
C07258116-hydroxycleroda-3,13(14)-dien-15,16-olide"16-hydroxycleroda-3,13(14)-dien-15,16-olide results in increased expression of BAD mRNA"21530604
C4779311L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate results in decreased phosphorylation of BAD protein12970779
C0326681-nitropyrene1-nitropyrene results in increased phosphorylation of BAD protein17240030
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [ETP-45299 results in decreased phosphorylation of BAD protein]"21051136
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in decreased phosphorylation of BAD protein"21051136
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased expression of BAD protein"22101421
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[U 0126 co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased expression of BAD protein"22101421
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BAD"25697951
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BAD mRNA"27589474
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [CXCL2 protein results in increased phosphorylation of BAD protein]15608143
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in increased expression of BAD protein]"19747539
C5465712,2'-cyclohexane-1,2-diylbis(azanediyl)bis(methylene)diphenoldichloroplatinum(II)"2,2'-cyclohexane-1,2-diylbis(azanediyl)bis(methylene)diphenoldichloroplatinum(II) results in decreased expression of BAD mRNA"19694485
C0930262,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside"2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAD protein]"23911879
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased phosphorylation of BAD protein]19596284
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in decreased phosphorylation of BAD protein]12438947
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tauroursodeoxycholic acid results in increased phosphorylation of and results in decreased activity of BAD protein]17559149
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [polyphenon E results in decreased phosphorylation of BAD protein]23285096
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of BAD protein12970779|1462807
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-onepolyphenon E promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of BAD protein]23285096
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in decreased expression of BAD protein modified form]]25895139
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
C0228302-methoxyestradiol2-methoxyestradiol results in decreased phosphorylation of BAD protein23967052
C5561683-(2-(3-(1-adamantyl)-4-hydroxyphenyl)-5-pyrimidinyl)-2-propenoic acid3-(2-(3-(1-adamantyl)-4-hydroxyphenyl)-5-pyrimidinyl)-2-propenoic acid results in decreased phosphorylation of BAD protein21548569
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in decreased phosphorylation of BAD protein"22290291
C5542893-hydroxylup-20(29)-ene-27,28-dioic acid dimethyl ester"3-hydroxylup-20(29)-ene-27,28-dioic acid dimethyl ester results in increased expression of BAD protein"20670616
C0153923-nitropropionic acid3-nitropropionic acid results in increased expression of BAD mRNA21945202
C0153923-nitropropionic acidnaringin inhibits the reaction [3-nitropropionic acid results in increased expression of BAD mRNA]21945202
C4967514-(1H-imidazol-1-yl)retinoic acid4-(1H-imidazol-1-yl)retinoic acid results in increased expression of BAD protein17145897|1738734
C4967514-(1H-imidazol-1-yl)retinoic acid4-(1H-imidazol-1-yl)retinoic acid results in increased expression of BAD protein17145897
C1191304-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide[4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide results in decreased expression of YWHAE protein] which results in increased localization of BAD protein17409426
C0553314-aminocrotonic acid4-aminocrotonic acid inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]14535961
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of BAD mRNA12419474
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of BAD protein24825450
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein18508827
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneSN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]18508827
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneU 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]18508827
C0415944-nonylphenol4-nonylphenol results in increased expression of BAD mRNA27087316
C0415944-nonylphenol4-nonylphenol results in increased expression of BAD protein26804764
C5762686-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide"6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in decreased phosphorylation of and affects the localization of BAD protein"27720946
C5762686-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide"AKT1 protein inhibits the reaction [6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in decreased phosphorylation of BAD protein]"27720946
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2L1 protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2 protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of BAD protein19407222
C5319376-O-angeloylenolin6-O-angeloylenolin results in increased expression of BAD protein21192922
C0030017-ketocholesterol7-ketocholesterol results in decreased phosphorylation of BAD protein15955068
C0539078-cyclopentyl-1,3-dimethylxanthine"[8-cyclopentyl-1,3-dimethylxanthine results in decreased activity of ADORA1 protein] inhibits the reaction [resveratrol results in increased phosphorylation of BAD protein]"15345477
C0428349,10-anthraquinone"9,10-anthraquinone analog results in increased expression of BAD protein"26915975
C0257249-methoxycamptothecin9-methoxycamptothecin results in increased expression of BAD mRNA23369935
D000082AcetaminophenAcetaminophen results in increased expression of BAD mRNA25704631
C043377acetochloracetochlor results in increased expression of BAD protein25291404
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cordycepin results in increased expression of BAD protein]21310227
D000111AcetylcysteineAcetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAD protein]22245127
D000111AcetylcysteineAcetylcysteine results in increased expression of BAD mRNA26332274
D000171Acrolein2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased phosphorylation of BAD protein]19596284
D000171AcroleinAcrolein results in increased phosphorylation of BAD protein19596284
D000171AcroleinAkt-I-1 compound inhibits the reaction [Acrolein results in increased phosphorylation of BAD protein]19596284
D000171Acroleinwortmannin inhibits the reaction [Acrolein results in increased phosphorylation of BAD protein]19596284
D000171AcroleinAcrolein results in increased expression of BAD mRNA18515264
C412373AG 1879AG 1879 results in decreased phosphorylation of BAD protein17186241
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2L1 protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2 protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of BAD protein19407222
D000393Air PollutantsAir Pollutants results in increased expression of and results in decreased phosphorylation of BAD protein28389379
D000393Air PollutantsAir Pollutants results in increased expression of BAD mRNA28389379
C501520Akt-I-1 compoundAkt-I-1 compound inhibits the reaction [Acrolein results in increased phosphorylation of BAD protein]19596284
D000496AlloxanAlloxan results in increased expression of BAD protein22138235
D000496AlloxanTaurine inhibits the reaction [Alloxan results in increased expression of BAD protein]22138235
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in increased expression of BAD protein"20197088
D024502alpha-Tocopherolalpha-Tocopherol results in increased expression of BAD mRNA26332274
C077990alvocidib[Imatinib Mesylate co-treated with alvocidib] results in decreased expression of BAD protein12231544
D0150812-Naphthylamine2-Naphthylamine results in decreased expression of BAD mRNA18247414
D000643Ammonium Chloride4-aminocrotonic acid inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]14535961
D000643Ammonium ChlorideAmmonium Chloride affects the expression of BAD mRNA16483693
D000643Ammonium ChlorideAmmonium Chloride results in decreased phosphorylation of BAD protein14535961|1503661
D000643Ammonium ChlorideCyclosporine inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]15036616
D000643Ammonium ChlorideTacrolimus inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]15036616
C540917anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione"anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione results in increased expression of BAD protein"19146838
C071942arctigeninarctigenin results in decreased phosphorylation of BAD protein25380086
C071942arctigeninQuercetin promotes the reaction [arctigenin results in decreased phosphorylation of BAD protein]25380086
C061640arjunolic acidarjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of BAD protein]21420465
C061640arjunolic acidarjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]19682444
D001149ArsenatesArsenates results in decreased expression of BAD mRNA15345372
C006632arsenic trioxide[arsenic trioxide co-treated with Curcumin] results in increased expression of BAD protein27430728
C006632arsenic trioxidearsenic trioxide results in decreased expression of BAD protein18349030
C006632arsenic trioxidearsenic trioxide results in decreased phosphorylation of BAD protein23239002
C006632arsenic trioxidearsenic trioxide results in increased expression of BAD mRNA17530438
C006632arsenic trioxidearsenic trioxide results in increased expression of BAD protein19364129|2743072
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of and results in increased activity of BAD protein18387645
C006632arsenic trioxidesalvin promotes the reaction [arsenic trioxide results in decreased phosphorylation of BAD protein]23239002
C006632arsenic trioxidearsenic trioxide results in decreased expression of BAD mRNA15073043
C006632arsenic trioxidearsenic trioxide affects the expression of BAD protein18618274
C006632arsenic trioxidearsenic trioxide results in decreased expression of BAD mRNA19730151
C006632arsenic trioxidearsenic trioxide results in increased expression of BAD protein28391263
C006632arsenic trioxidesalvianolic acid A inhibits the reaction [arsenic trioxide results in increased expression of BAD protein]28391263
C015001arsenitearsenite results in decreased expression of BAD mRNA15345372
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAD protein]21262251
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of BAD protein]21262251
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAD protein]21262251
D001241AspirinAspirin results in decreased expression of BAD mRNA20457246
D001374Azacitidine[Azacitidine co-treated with entinostat] results in increased expression of BAD mRNA21224363
D001374AzacitidineAzacitidine results in increased expression of BAD mRNA21224363
C010329azadirachtinazadirachtin results in increased expression of BAD mRNA20429769
C523470BBR3610[PX-866 co-treated with BBR3610] results in decreased phosphorylation of BAD protein20473884
D001554BenzeneBenzene results in increased expression of BAD protein18093815
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BAD protein"15698582
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of BAD protein"15698582
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in decreased expression of BAD protein15698582
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in increased phosphorylation of BAD protein15698582
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of BAD protein21392559
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BAD mRNA18247414
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BAD protein15698582
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of BAD protein15698582
D004958EstradiolEstradiol results in decreased expression of BAD mRNA23373633
D004958EstradiolEstradiol inhibits the reaction [Dimethylnitrosamine results in increased expression of BAD protein]14659978
D004958Estradiol[Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of BAD mRNA20732338
C006780bisphenol Abisphenol A results in increased expression of BAD mRNA28159858
C006780bisphenol Abisphenol A affects the expression of BAD mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of BAD mRNA26363213
C006780bisphenol Abisphenol A results in decreased expression of BAD protein21277958
C006780bisphenol Abisphenol A results in increased expression of BAD mRNA26049153
C006780bisphenol Abisphenol A results in increased expression of BAD mRNA25181051|2729622
C006780bisphenol Abisphenol A results in increased phosphorylation of BAD protein24884420
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of BAD mRNA12419474
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of BAD protein17419000
D020122tert-ButylhydroperoxideCurcumin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAD protein]15569404
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of BAD protein15569404
C018475butyraldehydebutyraldehyde results in increased expression of BAD mRNA26079696
D002101Cacodylic AcidCacodylic Acid results in increased expression of BAD mRNA22246474
D002101Cacodylic AcidCacodylic Acid results in increased expression of BAD protein22246474
D002101Cacodylic AcidCacodylic Acid results in increased expression of BAD mRNA16122865
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of BAD mRNA19426795
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BAD protein24291162
D019256Cadmium Chloridearjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of BAD protein]21420465
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BAD protein21420465
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BAD protein23717155
D019256Cadmium ChloridePlant Extracts inhibits the reaction [Cadmium Chloride results in increased expression of BAD protein]23717155
C034939cadmium sulfidecadmium sulfide results in increased expression of BAD mRNA27866839
D002118CalciumCalcium affects the expression of BAD mRNA15913539
D002211CapsaicinCapsaicin results in increased expression of BAD mRNA19502594
D002248Carbon MonoxideCarbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of BAD protein]18037988
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of BAD protein25445725
D002251Carbon TetrachlorideLipids inhibits the reaction [Carbon Tetrachloride results in increased expression of BAD protein]25445725
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of BAD mRNA16644059
D002251Carbon Tetrachloride[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BAD mRNA16610055
D000068579CelecoxibCelecoxib results in decreased activity of BAD protein19706164
D004390ChlorpyrifosChlorpyrifos results in increased expression of BAD protein26435000
D004390ChlorpyrifosMitoTEMPO inhibits the reaction [Chlorpyrifos results in increased expression of BAD protein]26435000
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of BAD mRNA28472532
C039671ciglitazoneciglitazone results in increased expression of BAD protein12065618
D003000ClonidineClonidine results in increased expression of BAD protein28115640
D003042CocaineCocaine affects the expression of BAD mRNA15681117
C024989coenzyme Q10coenzyme Q10 inhibits the reaction [Doxorubicin results in decreased phosphorylation of BAD protein]27087047
D003300CopperCopper analog results in decreased phosphorylation of BAD protein22000994
D003300CopperCopper analog results in increased expression of BAD protein21319953
C058120cordycepinAcetylcysteine inhibits the reaction [cordycepin results in increased expression of BAD protein]21310227
C058120cordycepincordycepin results in increased expression of BAD protein21310227
D003373Coumaric AcidsCoumaric Acids results in increased expression of BAD protein25824411
D003474Curcumin[arsenic trioxide co-treated with Curcumin] results in increased expression of BAD protein27430728
D003474CurcuminCurcumin results in increased expression of BAD mRNA19235267
D003474CurcuminCurcumin results in increased expression of BAD protein19235267
D003474CurcuminCurcumin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAD protein]15569404
C057862cyanoginosin LRcyanoginosin LR results in increased phosphorylation of BAD protein26506538|2735282
C560272cyclohexanecarboxylic acid (3-(2,5-dimethylbenzyloxy)-4-(methanesulfonylmethylamino)phenyl)amide"cyclohexanecarboxylic acid (3-(2,5-dimethylbenzyloxy)-4-(methanesulfonylmethylamino)phenyl)amide results in decreased expression of BAD protein modified form"21458568
D003520CyclophosphamideCyclophosphamide results in increased expression of BAD mRNA11599041
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in increased expression of BAD mRNA24244623
D016572CyclosporineCyclosporine results in decreased activity of BAD protein22155090
D016572CyclosporineCyclosporine results in increased expression of and results in increased phosphorylation of BAD protein22155090
D016572CyclosporineCyclosporine inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]15036616
C028972dan-shen root extractdan-shen root extract inhibits the reaction [IGF2 protein mutant form results in decreased expression of BAD protein modified form]23419388
C028972dan-shen root extractdan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of BAD protein]23419388
C028972dan-shen root extractfulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in decreased expression of BAD protein modified form]]23419388
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of BAD mRNA16940010
D013759DronabinolBAD results in increased susceptibility to Dronabinol17583570
D013759DronabinolDronabinol results in decreased phosphorylation of BAD protein17583570
C007262deoxynivalenoldeoxynivalenol results in increased phosphorylation of BAD protein15976193
D003907DexamethasoneDexamethasone results in decreased phosphorylation of BAD protein16644695
D003907DexamethasoneDexamethasone results in increased expression of BAD mRNA16644695
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in decreased phosphorylation of BAD protein]16644695
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of BAD mRNA]16644695
C042577diallyl trisulfidediallyl trisulfide results in decreased phosphorylation of BAD protein27566995
C061481dibenzoylmethanedibenzoylmethane results in increased expression of BAD protein21523861
C061481dibenzoylmethaneODC1 protein inhibits the reaction [dibenzoylmethane results in increased expression of BAD protein]21523861
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BAD mRNA21266533|2576577
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BAD mRNA21266533
D002945CisplatinBAD protein modified form results in decreased susceptibility to Cisplatin21849418
D002945CisplatinBAD results in decreased susceptibility to Cisplatin21849418
D002945CisplatinCisplatin promotes the reaction [Metformin results in increased expression of BAD protein]21388661
D002945CisplatinCisplatin results in increased expression of BAD mRNA20878077
D002945Cisplatin[PPM1A results in decreased phosphorylation of BAD protein] which results in increased susceptibility to Cisplatin21849418
D002945Cisplatin[PRKACA results in increased phosphorylation of BAD protein] which results in decreased susceptibility to Cisplatin21849418
D002945CisplatinY 27632 inhibits the reaction [Cisplatin results in increased expression of BAD mRNA]20878077
C000944dicrotophosdicrotophos results in decreased expression of BAD mRNA28302478
C020283diethanolaminediethanolamine results in decreased expression of BAD mRNA16014740
C020283diethanolaminediethanolamine results in decreased expression of BAD mRNA16014740
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of BAD mRNA25701202
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of BAD mRNA22610992
D004052Diethylnitrosamine[DMU-212 co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of BAD mRNA27048571
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of BAD mRNA15545218
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAD mRNA"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAD mRNA]"21294050
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of BAD protein14659978
D004128DimethylnitrosamineEstradiol inhibits the reaction [Dimethylnitrosamine results in increased expression of BAD protein]14659978
D004128Dimethylnitrosamineidoxifene inhibits the reaction [Dimethylnitrosamine results in increased expression of BAD protein]14659978
D004145DiosminDiosmin inhibits the reaction [Lipopolysaccharides results in increased expression of BAD protein]21477647
C558638DLBS 1425DLBS 1425 results in increased expression of BAD mRNA20703095
C521792DMU-212DMU-212 results in increased expression of BAD mRNA24055891
C521792DMU-212[DMU-212 co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of BAD mRNA27048571
C067311docetaxeldocetaxel results in decreased phosphorylation of BAD protein17317842
C067311docetaxelU 0126 promotes the reaction [docetaxel results in decreased phosphorylation of BAD protein]17317842
D004281Docosahexaenoic Acids[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased expression of BAD protein16963249
D004317DoxorubicinDoxorubicin affects the expression of BAD mRNA16705698
D004317DoxorubicinDoxorubicin promotes the reaction [MAPK14 protein results in decreased phosphorylation of BAD protein]16843435
D004317DoxorubicinDoxorubicin results in decreased expression of BAD protein modified form16438844
D004317DoxorubicinDoxorubicin results in decreased phosphorylation of BAD protein17359293|2088485
D004317DoxorubicinDoxorubicin results in increased expression of BAD protein25339540
D004317DoxorubicinPTEN protein promotes the reaction [Doxorubicin results in decreased expression of BAD protein modified form]16438844
D004317DoxorubicinPTEN protein promotes the reaction [Doxorubicin results in decreased phosphorylation of BAD protein]17359293
D004317DoxorubicinSildenafil Citrate promotes the reaction [Doxorubicin results in decreased phosphorylation of BAD protein]20884855
D004317DoxorubicinCarbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of BAD protein]18037988
D004317DoxorubicinDoxorubicin results in decreased expression of BAD mRNA26873546
D004317DoxorubicinDoxorubicin results in decreased phosphorylation of BAD protein18037988|1894861
D004317DoxorubicinDoxorubicin results in increased expression of BAD protein17673183
D004317DoxorubicinDoxycycline inhibits the reaction [Doxorubicin results in increased expression of BAD protein]17673183
D004317Doxorubicincoenzyme Q10 inhibits the reaction [Doxorubicin results in decreased phosphorylation of BAD protein]27087047
D004317DoxorubicinDoxorubicin results in decreased phosphorylation of BAD protein27087047
D004317DoxorubicinDoxorubicin results in increased expression of BAD protein12967636|1863259
D004317DoxorubicinDoxorubicin results in increased phosphorylation of BAD protein18845810
D004317DoxorubicinGinkgo biloba extract inhibits the reaction [Doxorubicin results in increased expression of BAD protein]18632596
D004317DoxorubicinHMOX1 protein inhibits the reaction [Doxorubicin results in increased phosphorylation of BAD protein]18845810
D004317DoxorubicinHSPD1 protein inhibits the reaction [Doxorubicin results in increased expression of BAD protein]12967636
D004318DoxycyclineDoxycycline inhibits the reaction [Doxorubicin results in increased expression of BAD protein]17673183
D004610Ellagic AcidEllagic Acid results in increased expression of BAD protein23554011
C118739entinostat[Azacitidine co-treated with entinostat] results in increased expression of BAD mRNA21224363
C062669epicatechin gallateepicatechin gallate results in increased expression of BAD protein21945981
D004967EstrogensEstrogens deficiency results in increased phosphorylation of BAD protein17186241
D000431Ethanol[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BAD mRNA16610055
D000431EthanolEthanol results in decreased expression of BAD mRNA23273579
D000431EthanolEthanol results in increased expression of and results in decreased phosphorylation of BAD protein12700235
D000431EthanolEthanol results in increased expression of BAD mRNA20655511
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of BAD mRNA16940010
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of BAD mRNA23649840
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of BAD gene27776689
C554740ETP-45299"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [ETP-45299 results in decreased phosphorylation of BAD protein]"21051136
D005054EugenolEugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA]20434464
D005473FluoxetineFluoxetine results in increased expression of BAD mRNA21497159
D005485FlutamideFlutamide results in increased expression of BAD protein modified form20850791
C473894fujiflavone P40fujiflavone P40 results in decreased expression of BAD mRNA14656947
C070081fulvestrantfulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in decreased expression of BAD protein modified form]]23419388
D005665FurosemideFurosemide affects the expression of BAD mRNA17497460
C002469fusarenon-Xfusarenon-X results in increased expression of BAD mRNA24983900
D019833Genistein[Genistein co-treated with Methoxychlor] results in increased expression of BAD mRNA21782745
C063170Ginkgo biloba extractGinkgo biloba extract inhibits the reaction [Doxorubicin results in increased expression of BAD protein]18632596
C035054ginsenoside Rg12-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
C035054ginsenoside Rg1ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]17123556
C035054ginsenoside Rg1Mifepristone inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
C035054ginsenoside Rg1SH-6 compound inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
D005947GlucoseGlucose results in decreased phosphorylation of and results in decreased activity of BAD protein20370652
D005947Glucose[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of BAD protein]20370652
D006046Gold[Quercetin analog co-treated with Gold analog] results in increased expression of BAD protein27470402
D006108Graphite[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAD protein25446327
D006830Hydralazine[Hydralazine co-treated with Valproic Acid] results in increased expression of BAD mRNA17183730
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of BAD protein27494022
D006861Hydrogen PeroxidePI103 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of BAD protein]27494022
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of BAD protein]27494022
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of BAD mRNA14689451
C031927hydroquinonehydroquinone results in decreased expression of BAD mRNA15452088
C071362idoxifeneidoxifene inhibits the reaction [Dimethylnitrosamine results in increased expression of BAD protein]14659978
D000068877Imatinib Mesylate[Imatinib Mesylate co-treated with alvocidib] results in decreased expression of BAD protein12231544
D007213IndomethacinIndomethacin results in decreased expression of BAD protein18678619
D007213Indomethacin[Indomethacin results in decreased expression of YWHAE protein] which results in increased localization of BAD protein17409426
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of BAD mRNA25613284
C506002ircinin-1ircinin-1 results in increased expression of BAD protein16163705
D007530IsofluraneIsoflurane affects the expression of BAD protein25597859
D007530IsofluraneIsoflurane results in decreased expression of BAD mRNA16978161
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of BAD protein11222086
C561695(+)-JQ1 compound[(+)-JQ1 compound co-treated with vemurafenib] results in increased expression of BAD protein27169980
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of BAD mRNA23086925
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of BAD protein24297863
C510621KCC 009KCC 009 results in decreased expression of BAD protein16170020
D007654KetoconazoleKetoconazole results in increased expression of BAD mRNA25787151
C008261lead acetatelead acetate affects the expression of BAD protein18618274
D008055LipidsLipids inhibits the reaction [Carbon Tetrachloride results in increased expression of BAD protein]25445725
D008070LipopolysaccharidesDiosmin inhibits the reaction [Lipopolysaccharides results in increased expression of BAD protein]21477647
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of BAD protein21477647|2320073
D008070Lipopolysaccharidestigecycline inhibits the reaction [Lipopolysaccharides results in increased expression of BAD protein]23200736
C044660LY 171883LY 171883 results in increased expression of BAD protein12065618
D008344Maneb[Paraquat co-treated with Maneb] results in increased phosphorylation of BAD protein15824117
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of BAD protein]22915474
D008353MannitolMannitol results in increased phosphorylation of BAD protein15786717
D008353Mannitolwortmannin inhibits the reaction [Mannitol results in increased phosphorylation of BAD protein]15786717
C011907melamine"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of BAD protein]"22915474
C011907melaminemanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of BAD protein]22915474
C011907melaminemelamine results in increased expression of BAD protein22915474
C011907melamineTGFB1 protein affects the reaction [melamine results in increased expression of BAD protein]22915474
D008550MelatoninMelatonin promotes the reaction [YWHAB protein binds to BAD protein]18078454
D008550MelatoninMelatonin results in increased phosphorylation of BAD protein18078454
D008550MelatoninMelatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of BAD protein]21138475
D008627Mercuric ChlorideMercuric Chloride results in increased expression of BAD protein21373768
D008628MercuryMercury results in decreased expression of BAD mRNA19937285
D008687MetforminCisplatin promotes the reaction [Metformin results in increased expression of BAD protein]21388661
D008687MetforminMetformin results in increased expression of BAD protein21388661
D008727MethotrexateMethotrexate results in increased expression of BAD mRNA23406595
D008727MethotrexateMethotrexate results in increased expression of BAD protein23406595
D008727MethotrexateMethotrexate results in increased expression of BAD protein modified form23406595
D008731Methoxychlor[Genistein co-treated with Methoxychlor] results in increased expression of BAD mRNA21782745
D008731MethoxychlorMethoxychlor results in increased expression of BAD mRNA21782745
D008748MethylcholanthreneMethylcholanthrene results in increased expression of BAD mRNA23273579
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of BAD mRNA28001369
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of BAD protein28821999
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of BAD mRNA20153410
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of BAD mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BAD mRNA"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BAD mRNA"20188158
D008769MethylnitronitrosoguanidineEugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA]20434464
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in decreased expression of BAD mRNA20434464
D008770Methylnitrosourea[Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of BAD mRNA20732338
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of BAD protein18037221|2435830
D0156551-Methyl-4-phenylpyridiniumML 9 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAD protein]24358303
D0156551-Methyl-4-phenylpyridiniumMRS 1845 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAD protein]24358303
D0156551-Methyl-4-phenylpyridiniumSTIM1 mutant form inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAD protein]24358303
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAD protein"23911879
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAD protein]"23911879
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in decreased phosphorylation of BAD protein]16644695
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of BAD mRNA]16644695
D015735MifepristoneMifepristone inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
D016685MitomycinMitomycin results in increased expression of BAD protein16186332
C555916MitoTEMPOMitoTEMPO inhibits the reaction [Chlorpyrifos results in increased expression of BAD protein]26435000
C056218ML 9ML 9 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAD protein]24358303
C008542monodansylcadaverinemonodansylcadaverine results in decreased expression of BAD protein16170020
C107728MRS 1191[MRS 1191 results in decreased activity of ADORA3 protein] inhibits the reaction [resveratrol results in increased phosphorylation of BAD protein]15345477
C503978MRS 1845MRS 1845 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAD protein]24358303
D009151Mustard GasMustard Gas results in decreased phosphorylation of BAD protein16935404
D009151Mustard GasN-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in decreased phosphorylation of BAD protein]16935404
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the localization of and results in decreased phosphorylation of BAD protein12629175
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [BAD protein binds to BCL2L1 protein]12629175
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of BAD protein12629175
C482378N-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugateN-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugate results in increased expression of BAD protein16749867
C033772N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamideN-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in decreased phosphorylation of BAD protein]16935404
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of BAD mRNA"23634900
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of BAD mRNA"25620056
C073873naphtho(1,2-b)furan-4,5-dione"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in increased expression of BAD protein]"19747539
C073873naphtho(1,2-b)furan-4,5-dione"naphtho(1,2-b)furan-4,5-dione results in increased expression of BAD protein"19747539|2019708
C073873naphtho(1,2-b)furan-4,5-dione"pyrazolanthrone inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in increased expression of BAD protein]"19747539
C005274naringinnaringin inhibits the reaction [3-nitropropionic acid results in increased expression of BAD mRNA]21945202
C546012N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamideN-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide results in increased expression of BAD protein27470402
C119536nickel acetateAcetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAD protein]22245127
C119536nickel acetatenickel acetate results in increased expression of BAD protein22245127
C022838nickel chloridenickel chloride affects the expression of BAD mRNA22546817
C022838nickel chloridenickel chloride results in increased expression of BAD protein20391133
D009534Niclosamide[Niclosamide binds to Polyethyleneimine] which results in increased expression of BAD mRNA25988281
D009538NicotineNicotine results in decreased expression of BAD mRNA18247414
D009538NicotineNicotine results in decreased phosphorylation of BAD protein20447445
C042198nimbolidenimbolide results in increased expression of BAD mRNA20429769
D026423S-Nitroso-N-AcetylpenicillamineMelatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of BAD protein]21138475
D026423S-Nitroso-N-AcetylpenicillamineS-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of BAD protein21138475
C069741norcantharidinnorcantharidin results in increased expression of BAD protein21266192
C067207obacunoneobacunone results in increased expression of BAD protein25592883
C411188obacunone glucosideobacunone glucoside results in increased expression of BAD protein25592883
C464660obeticholic acidobeticholic acid results in decreased expression of BAD mRNA27939613
C025589ochratoxin ABNIP3L protein inhibits the reaction [ochratoxin A results in increased expression of BAD mRNA]24755393
C025589ochratoxin Aochratoxin A results in increased expression of BAD mRNA24755393
C025589ochratoxin Aochratoxin A results in increased expression of BAD mRNA19562491
C016340o,p'-DDT"o,p'-DDT analog results in decreased expression of BAD mRNA"22937105
C016340o,p'-DDT"o,p'-DDT results in decreased expression of BAD mRNA"22937105
D009942Organometallic CompoundsOrganometallic Compounds results in decreased phosphorylation of BAD protein17210701
D010100OxygenOxygen affects the reaction [AHR protein results in decreased expression of BAD mRNA]27103661
D010100OxygenOxygen deficiency results in increased expression of BAD mRNA26476374
D010100OxygenQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of BAD mRNA]26476374
D017239PaclitaxelPaclitaxel results in increased expression of BAD mRNA10822281
D017239PaclitaxelPaclitaxel results in increased expression of BAD protein10822281
D017239Paclitaxel[PD168393 co-treated with Paclitaxel] results in increased expression of BAD protein16413505
D010269Paraquat[Paraquat co-treated with Maneb] results in increased phosphorylation of BAD protein15824117
D010269ParaquatParaquat results in decreased expression of BAD mRNA18836921
D010269ParaquatParaquat results in increased expression of BAD protein27442881
D010269ParaquatTLR4 gene mutant form inhibits the reaction [Paraquat results in increased expression of BAD protein]27442881
D010269ParaquatParaquat results in increased expression of BAD mRNA17935786
D052638Particulate Matter[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of BAD protein28013216
D052638Particulate MatterParticulate Matter results in increased expression of BAD mRNA24216475
C509204PD168393[PD168393 co-treated with Paclitaxel] results in increased expression of BAD protein16413505
D010416PentachlorophenolPentachlorophenol results in increased expression of BAD mRNA19442831
D010634Phenobarbital[DMU-212 co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of BAD mRNA27048571
D010634PhenobarbitalPhenobarbital results in decreased expression of BAD mRNA16940010|2327357
C522973PI103PI103 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of BAD protein]27494022
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BAD mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of BAD mRNA15618236
C037850PK 11195PK 11195 results in decreased expression of BAD protein11266385
C037850PK 11195PK 11195 results in decreased phosphorylation of BAD protein11266385
D010936Plant ExtractsPlant Extracts results in decreased expression of BAD mRNA23557933
D010936Plant ExtractsPlant Extracts results in increased expression of BAD protein20670616
D010936Plant ExtractsPlant Extracts inhibits the reaction [Cadmium Chloride results in increased expression of BAD protein]23717155
D010936Plant ExtractsPlant Extracts results in increased expression of BAD mRNA26332274
D028321Plant PreparationsLRP1 protein promotes the reaction [Plant Preparations results in increased phosphorylation of BAD protein]27262837
D028321Plant PreparationsPlant Preparations results in increased phosphorylation of BAD protein27262837
D028321Plant PreparationsPlant Preparations results in increased expression of BAD mRNA24973489
D011094Polyethyleneimine[Niclosamide binds to Polyethyleneimine] which results in increased expression of BAD mRNA25988281
C472086polyphenon E2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [polyphenon E results in decreased phosphorylation of BAD protein]23285096
C472086polyphenon Epolyphenon E promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of BAD protein]23285096
C472086polyphenon Epolyphenon E results in decreased phosphorylation of BAD protein23285096
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAD protein]21262251
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of BAD protein]21262251
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAD protein]21262251
D011192Potassium DichromatePotassium Dichromate results in decreased phosphorylation of BAD protein21262251
D011192Potassium DichromatePotassium Dichromate results in increased expression of BAD protein21262251
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of BAD mRNA19162173
D011374Progesterone[Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of BAD mRNA20732338
D011374ProgesteroneProgesterone results in decreased expression of BAD mRNA15941375
C487679protectin D1protectin D1 results in decreased expression of BAD protein16077186
C107773pterostilbenepterostilbene results in increased expression of BAD protein20681671
C496788PX-866[PX-866 co-treated with BBR3610] results in decreased phosphorylation of BAD protein20473884
C496788PX-866PX-866 results in decreased phosphorylation of BAD protein20473884
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in increased expression of BAD protein]"19747539
C031280pyrazole[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BAD mRNA16610055
D011794Quercetin[Quercetin analog co-treated with Gold analog] results in increased expression of BAD protein27470402
D011794QuercetinQuercetin promotes the reaction [arctigenin results in decreased phosphorylation of BAD protein]25380086
D011794QuercetinQuercetin promotes the reaction [BCL2L1 protein binds to BAD protein]18455702
D011794QuercetinQuercetin results in decreased phosphorylation of BAD protein18455702|2043863
D011794QuercetinQuercetin results in increased expression of BAD mRNA20658310
D011794QuercetinQuercetin results in increased expression of BAD protein14688022|1476752
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAD mRNA]"21294050
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of BAD protein]27494022
D011794QuercetinQuercetin results in decreased phosphorylation of BAD protein12826665
D011794QuercetinQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of BAD mRNA]26476374
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased cleavage of BAD protein12084714
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in decreased expression of BAD mRNA25800948
C059514resveratrolresveratrol results in increased expression of BAD mRNA25436977
C059514resveratrolresveratrol results in increased expression of BAD protein16731767|2433153
C059514resveratrolresveratrol results in decreased expression of BAD protein17872969
C059514resveratrol[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of BAD protein]20370652
C059514resveratrolresveratrol results in increased expression of BAD mRNA22610192
C059514resveratrol"[8-cyclopentyl-1,3-dimethylxanthine results in decreased activity of ADORA1 protein] inhibits the reaction [resveratrol results in increased phosphorylation of BAD protein]"15345477
C059514resveratrol[MRS 1191 results in decreased activity of ADORA3 protein] inhibits the reaction [resveratrol results in increased phosphorylation of BAD protein]15345477
C059514resveratrolresveratrol results in increased expression of BAD protein23262250
C059514resveratrolresveratrol results in increased phosphorylation of BAD protein15345477
C089730rosiglitazonerosiglitazone results in increased expression of BAD mRNA17639046
D012402RotenoneRotenone results in decreased phosphorylation of BAD protein15280438
D012402RotenoneTacrolimus inhibits the reaction [Rotenone results in decreased phosphorylation of BAD protein]15280438
D012402RotenoneRotenone results in decreased expression of BAD mRNA23186747
D012402Rotenone2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
D012402Rotenoneginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]17123556
D012402RotenoneMifepristone inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
D012402RotenoneRotenone results in increased phosphorylation of BAD protein17123556
D012402RotenoneSH-6 compound inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
C085746rottlerin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in decreased expression of BAD protein modified form]]25895139
C085746rottlerinrottlerin inhibits the reaction [trimethyltin results in decreased expression of BAD protein modified form]25895139
D012428RutheniumRuthenium results in decreased phosphorylation of BAD protein17210701
D017975Ruthenium CompoundsRuthenium Compounds results in decreased phosphorylation of BAD protein17210701
C066201salvianolic acid Asalvianolic acid A inhibits the reaction [arsenic trioxide results in increased expression of BAD protein]28391263
C018381salvinsalvin promotes the reaction [arsenic trioxide results in decreased phosphorylation of BAD protein]23239002
C018381salvinsalvin results in decreased phosphorylation of BAD protein23239002
C018381salvinsalvin results in increased expression of BAD protein28918123
C097256semapimodsemapimod results in decreased expression of BAD protein15947118
C516024SH-6 compoundSH-6 compound inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]17123556
D000068677Sildenafil CitrateSildenafil Citrate promotes the reaction [Doxorubicin results in decreased phosphorylation of BAD protein]20884855
D019821Simvastatin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in decreased phosphorylation of BAD protein]12438947
D019821SimvastatinSimvastatin results in decreased phosphorylation of BAD protein12438947
D019821SimvastatinIGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of BAD protein]27734117
D019821SimvastatinSimvastatin results in decreased phosphorylation of BAD protein27734117
D020123SirolimusSirolimus inhibits the reaction [IL2 protein results in increased expression of BAD mRNA]11355896
C118258SN50 peptideSN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]18508827
C118258SN50 peptideSN50 peptide results in decreased phosphorylation of BAD protein12970779
C017947sodium arsenitesodium arsenite results in increased expression of BAD mRNA10910055
C017947sodium arsenitesodium arsenite results in increased expression of BAD protein19429265|1961656
C017947sodium arseniteTaurine inhibits the reaction [sodium arsenite results in increased expression of BAD protein]19429265|1961656
C016104sodium bichromatesodium bichromate affects the expression of BAD mRNA11960910
C016104sodium bichromatesodium bichromate results in increased expression of BAD mRNA12325037
D012969Sodium FluorideSodium Fluoride inhibits the reaction [CA2 protein binds to BAD protein]21708216
D012969Sodium Fluoride[Sodium Fluoride inhibits the reaction [CA2 protein binds to BAD protein]] promotes the reaction [BAD protein binds to BCL2 protein]21708216
D012969Sodium FluorideSodium Fluoride promotes the reaction [BAD protein binds to BCL2 protein]21708216
D012969Sodium FluorideSodium Fluoride results in increased expression of and results in decreased phosphorylation of BAD protein21708216
C471405sorafenibsorafenib results in decreased phosphorylation of BAD protein16452220
C471405sorafenibsorafenib results in increased expression of BAD protein18200035
C471405sorafenibsorafenib results in decreased expression of BAD mRNA21360571
D013148SpironolactoneSpironolactone results in decreased expression of BAD protein19114643
D013148SpironolactoneSpironolactone results in increased phosphorylation of BAD protein19114643
D013267StilbenesStilbenes analog results in decreased phosphorylation of BAD protein18449500
D013311Streptozocinarjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]19682444
D013311StreptozocinStreptozocin results in decreased expression of BAD protein15976052
D013311StreptozocinStreptozocin results in increased expression of BAD protein19682444
D013311StreptozocinStreptozocin results in increased phosphorylation of and results in decreased activity of BAD protein15976052
C061636suillinsuillin results in increased expression of BAD protein19616521
D013467SulindacSulindac inhibits the reaction [EGF protein results in increased phosphorylation of BAD protein]12566304
D013467SulindacSulindac results in decreased expression of BAD protein12566304
C025462sulindac sulfidesulindac sulfide promotes the reaction [BAD protein binds to YWHAE protein]17409426
C025462sulindac sulfidesulindac sulfide results in decreased expression of BAD protein18678619
C025462sulindac sulfide[sulindac sulfide results in decreased expression of YWHAE protein] which results in increased localization of BAD protein17409426|1867861
C025462sulindac sulfidesulindac sulfide results in increased localization of BAD protein18678619
D014284TriiodothyronineTriiodothyronine results in decreased expression of BAD protein16021636
D014284TriiodothyronineTriiodothyronine results in decreased expression of BAD protein16021636
D016559TacrolimusTacrolimus inhibits the reaction [Rotenone results in decreased phosphorylation of BAD protein]15280438
D016559TacrolimusTacrolimus inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]15036616
D013629TamoxifenTamoxifen results in increased phosphorylation of BAD protein17186241
D013654TaurineTaurine inhibits the reaction [Alloxan results in increased expression of BAD protein]22138235
D013654TaurineTaurine inhibits the reaction [sodium arsenite results in increased expression of BAD protein]19429265|1961656
C031655tauroursodeoxycholic acid2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tauroursodeoxycholic acid results in increased phosphorylation of and results in decreased activity of BAD protein]17559149
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased phosphorylation of and results in decreased activity of BAD protein17559149
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased phosphorylation of and affects the localization of BAD protein15190125
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased phosphorylation of BAD protein12721362
C031655tauroursodeoxycholic acidwortmannin inhibits the reaction [tauroursodeoxycholic acid results in increased phosphorylation of and affects the localization of BAD protein]15190125
D013739TestosteroneTestosterone deficiency results in increased expression of BAD protein modified form20850791
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BAD mRNA17823287
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of BAD mRNA21570461|2468072
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BAD mRNA12167310|1597263
C117155tetracycline CMT-3tetracycline CMT-3 results in increased expression of BAD protein15688368
D013755Tetradecanoylphorbol Acetate[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAD protein25446327
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of BAD mRNA25613284
C014215tetrahydropalmatinetetrahydropalmatine results in increased expression of BAD protein20109541
C026995thallium acetatethallium acetate results in increased expression of BAD protein15965099
D019284ThapsigarginThapsigargin results in increased expression of BAD mRNA22378314
D013853ThioacetamideThioacetamide results in increased expression of BAD mRNA16456712
D013853ThioacetamideThioacetamide results in increased expression of BAD protein16937528
D013852ThiotepaThiotepa results in increased expression of BAD protein10822281
C119092tigecyclinetigecycline inhibits the reaction [Lipopolysaccharides results in increased expression of BAD protein]23200736
C009495titanium dioxidetitanium dioxide affects the expression of BAD mRNA19695317
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of BAD mRNA16137721
D014212TretinoinTretinoin results in increased expression of BAD mRNA18230668
D014212Tretinoin[Tretinoin co-treated with zoledronic acid] results in increased expression of BAD protein20349282
D014212TretinoinTretinoin results in decreased phosphorylation of BAD protein16411021
D014212TretinoinTretinoin results in increased expression of BAD protein17387344
D014222Triamcinolone AcetonideTriamcinolone Acetonide results in increased expression of BAD protein15987869
C011559tributyltinPRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BAD protein modified form]25895139
D014241TrichloroethyleneTrichloroethylene results in increased expression of BAD mRNA22751198
D014241TrichloroethylenePPARA protein inhibits the reaction [Trichloroethylene results in increased expression of BAD protein]15363585
D014241TrichloroethyleneTrichloroethylene results in increased expression of BAD mRNA15363585
C012589trichostatin Atrichostatin A results in increased expression of BAD mRNA15901671
C046488trimethyltin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in decreased expression of BAD protein modified form]]25895139
C046488trimethyltinrottlerin inhibits the reaction [trimethyltin results in decreased expression of BAD protein modified form]25895139
C046488trimethyltintrimethyltin results in decreased expression of BAD protein modified form25895139
D014415TunicamycinTunicamycin results in increased expression of BAD mRNA22378314
C113580U 0126"[U 0126 co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased expression of BAD protein"22101421
C113580U 0126U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]18508827
C113580U 0126U 0126 inhibits the reaction [EGF protein results in increased phosphorylation of BAD protein]12566304
C113580U 0126U 0126 promotes the reaction [docetaxel results in decreased phosphorylation of BAD protein]17317842
C113580U 0126U 0126 results in increased expression of BAD protein22101421
D014635Valproic AcidValproic Acid results in increased expression of BAD mRNA15901671
D014635Valproic Acid[Hydralazine co-treated with Valproic Acid] results in increased expression of BAD mRNA17183730
D014635Valproic AcidValproic Acid affects the expression of BAD protein15379904
C459559vaticanol Cvaticanol C results in decreased phosphorylation of BAD protein15725661
D001335Vehicle Emissions[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of BAD protein28013216
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of BAD gene25560391
D001335Vehicle EmissionsVehicle Emissions results in increased expression of BAD mRNA24216475
C551177vemurafenib[(+)-JQ1 compound co-treated with vemurafenib] results in increased expression of BAD protein27169980
D002762CholecalciferolCholecalciferol results in increased phosphorylation of BAD protein18628207
D002762Cholecalciferol[Cholecalciferol results in increased phosphorylation of BAD protein] inhibits the reaction [BAD protein binds to BCL2L1 protein]18628207
C111237vorinostat[vorinostat co-treated with TNFSF10 protein] results in decreased expression of BAD protein modified form19643600
C111237vorinostatvorinostat results in increased expression of BAD protein19875160
C009684withaferin Awithaferin A results in decreased expression of and results in decreased phosphorylation of BAD protein20438634
C009687wortmanninwortmannin inhibits the reaction [Acrolein results in increased phosphorylation of BAD protein]19596284
C009687wortmanninwortmannin inhibits the reaction [CXCL2 protein results in increased phosphorylation of BAD protein]15608143
C009687wortmanninwortmannin inhibits the reaction [Mannitol results in increased phosphorylation of BAD protein]15786717
C009687wortmanninwortmannin inhibits the reaction [tauroursodeoxycholic acid results in increased phosphorylation of and affects the localization of BAD protein]15190125
C009687wortmanninwortmannin results in decreased phosphorylation of BAD protein15190125
C108830Y 27632Y 27632 inhibits the reaction [Cisplatin results in increased expression of BAD mRNA]20878077
C108830Y 27632Y 27632 results in decreased expression of BAD mRNA20878077
C088658zoledronic acid[Tretinoin co-treated with zoledronic acid] results in increased expression of BAD protein20349282
C088658zoledronic acidzoledronic acid results in increased expression of BAD mRNA19036117

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI9305851  9388232  9463381  9973195  10949025  11526496  
11583631  15131699  15694340  16189514  17446862  17485524  
19427857  19427863  19667065  20005908  20179209  20603619  
21081150  21988832  22000515  23397142  24008843  25241761  
25416956  26871637  
GO:0005543phospholipid binding-IMP21081150  
GO:0008289lipid binding-IDA19667065  
GO:0008656cysteine-type endopeptidase activator activity involved in apoptotic process-IBA21873635  
GO:0008656cysteine-type endopeptidase activator activity involved in apoptotic process-IDA18402937  
GO:0019901protein kinase binding-IBA21873635  
GO:0019901protein kinase binding-IPI17270021  
GO:0019903protein phosphatase binding-IBA21873635  
GO:0030346protein phosphatase 2B binding-IEA-  
GO:0043422protein kinase B binding-IEA-  
GO:0046982protein heterodimerization activity-IEA-  
GO:007188914-3-3 protein binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001836release of cytochrome c from mitochondria-IBA21873635  
GO:0001836release of cytochrome c from mitochondria-IEA-  
GO:0001844protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-TAS-  
GO:0006007glucose catabolic process-IEA-  
GO:0006915apoptotic process-IDA19667065  
GO:0006915apoptotic process-TAS7834748  
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process-ISS-  
GO:0007283spermatogenesis-IEA-  
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors-IEA-  
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage-IEA-  
GO:0009749response to glucose-IEA-  
GO:0010508positive regulation of autophagy-TAS18309324  
GO:0010918positive regulation of mitochondrial membrane potential-ISS-  
GO:0019050suppression by virus of host apoptotic process-IEA-  
GO:0019221cytokine-mediated signaling pathway-IEA-  
GO:0021987cerebral cortex development-IEA-  
GO:0032024positive regulation of insulin secretion-ISS-  
GO:0032355response to estradiol-IEA-  
GO:0032570response to progesterone-IEA-  
GO:0033133positive regulation of glucokinase activity-ISS-  
GO:0033574response to testosterone-IEA-  
GO:0034201response to oleic acid-IEA-  
GO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulus-IEA-  
GO:0042542response to hydrogen peroxide-IEA-  
GO:0042593glucose homeostasis-ISS-  
GO:0043065positive regulation of apoptotic process-IDA9388232  
GO:0043065positive regulation of apoptotic process-IMP17289999  
GO:0043200response to amino acid-IEA-  
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-IDA18402937  
GO:0044342type B pancreatic cell proliferation-ISS-  
GO:0045471response to ethanol-IEA-  
GO:0045579positive regulation of B cell differentiation-IEA-  
GO:0045582positive regulation of T cell differentiation-IEA-  
GO:0045862positive regulation of proteolysis-IDA18387192  
GO:0046031ADP metabolic process-ISS-  
GO:0046034ATP metabolic process-ISS-  
GO:0046902regulation of mitochondrial membrane permeability-IBA21873635  
GO:0046902regulation of mitochondrial membrane permeability-IMP20700721  
GO:0046931pore complex assembly-IDA19667065  21081150  
GO:0050679positive regulation of epithelial cell proliferation-IMP19593445  
GO:0051384response to glucocorticoid-IEA-  
GO:0051592response to calcium ion-IEA-  
GO:0060139positive regulation of apoptotic process by virus-IEA-  
GO:0060154cellular process regulating host cell cycle in response to virus-IEA-  
GO:0071247cellular response to chromate-IEA-  
GO:0071260cellular response to mechanical stimulus-IEP19593445  
GO:0071316cellular response to nicotine-IDA18676776  
GO:0071396cellular response to lipid-IEA-  
GO:0071456cellular response to hypoxia-IBA21873635  
GO:0071456cellular response to hypoxia-IEP20810912  
GO:0090200positive regulation of release of cytochrome c from mitochondria-IMP17289999  
GO:0097191extrinsic apoptotic signaling pathway-IBA21873635  
GO:0097191extrinsic apoptotic signaling pathway-IMP18852119  
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand-IEA-  
GO:0097193intrinsic apoptotic signaling pathway-IBA21873635  
GO:0097193intrinsic apoptotic signaling pathway-IMP18676776  
GO:0097202activation of cysteine-type endopeptidase activity-IBA21873635  
GO:0097202activation of cysteine-type endopeptidase activity-IDA18387192  
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-TAS-  
GO:1901216positive regulation of neuron death-IEA-  
GO:1902220positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress-IEA-  
GO:2000078positive regulation of type B pancreatic cell development-ISS-  
GO:2001244positive regulation of intrinsic apoptotic signaling pathway-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005739mitochondrion-IBA21873635  
GO:0005739mitochondrion-IDA-  
GO:0005741mitochondrial outer membrane-IDA20700721  
GO:0005741mitochondrial outer membrane-TAS-  
GO:0005829cytosol-IBA21873635  
GO:0005829cytosol-IDA20700721  
GO:0005829cytosol-TAS-  
KEGG ID KEGG Term
hsa04012ErbB signaling pathway
hsa04210Apoptosis
hsa04370VEGF signaling pathway
hsa04510Focal adhesion
hsa04722Neurotrophin signaling pathway
hsa04910Insulin signaling pathway
hsa05010Alzheimer's disease
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa05145Toxoplasmosis
hsa05160Hepatitis C
hsa05200Pathways in cancer
hsa05210Colorectal cancer
hsa05212Pancreatic cancer
hsa05213Endometrial cancer
hsa05215Prostate cancer
hsa05218Melanoma
hsa05220Chronic myeloid leukemia
hsa05221Acute myeloid leukemia
hsa05223Non-small cell lung cancer
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisIEA
R-HSA-109581ApoptosisTAS
R-HSA-109606Intrinsic Pathway for ApoptosisIEA
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111447Activation of BAD and translocation to mitochondria IEA
R-HSA-111447Activation of BAD and translocation to mitochondria TAS
R-HSA-111453BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 membersTAS
R-HSA-114452Activation of BH3-only proteinsIEA
R-HSA-114452Activation of BH3-only proteinsTAS
R-HSA-1257604PIP3 activates AKT signalingIEA
R-HSA-162582Signal TransductionIEA
R-HSA-162582Signal TransductionTAS
R-HSA-1643685DiseaseTAS
R-HSA-193648NRAGE signals death through JNKTAS
R-HSA-193704p75 NTR receptor-mediated signallingTAS
R-HSA-198323AKT phosphorylates targets in the cytosolIEA
R-HSA-204998Cell death signalling via NRAGE, NRIF and NADETAS
R-HSA-2219528PI3K/AKT Signaling in CancerTAS
R-HSA-5357801Programmed Cell DeathIEA
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5663202Diseases of signal transductionTAS
R-HSA-5674400Constitutive Signaling by AKT1 E17K in CancerTAS
R-HSA-73887Death Receptor SignallingTAS
R-HSA-9006925Intracellular signaling by second messengersIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18069751Smoking in inflammatory bowel diseases: good, bad or ugly? (2007 Dec 14)Lakatos PLWorld J Gastroenterol
28186314Psychopathological profile and prevalence of dual pathology on patients with alcoholic dependence undergoing outpatient treatment. (2017 Jan)Garcia-Carretero MAActas Esp Psiquiatr
5141023[The Bad Nauheim smoking withdrawal therapy]. (1971)Hammer OVerh Dtsch Ges Kreislaufforsch
10635075[Acrodystrophic neuropathy of Bureau and Barriere]. (1999 Dec)Dilhuydy MSRev Med Interne
11350996Food intake patterns, self rated health and mortality in Danish men and women. A prospective observational study. (2001 Jun)Osler MJ Epidemiol Community Health
19811387The multiple facets of cigarette addiction and what they mean for encouraging and helping smokers to stop. (2009 Aug)West RCOPD
17504665[Diabetes mellitus in hypertensive population attended in Primary Care in Spain. Blood pressure and lipid control rates]. (2007 May)Escobar CRev Clin Esp
20447445The effect of prenatal nicotine exposure on PDGFR-mediated anti-apoptotic mechanism in the caudal brainstem of developing rat. (2010 Jun 30)Simakajornboon NNeurosci Lett
26038362The Association of Pain With Smoking and Quit Attempts in an Electronic Diary Study of Cancer Patients Trying to Quit. (2016 Jun)Aigner CJNicotine Tob Res
1475645Coronary risk factors in middle-aged men as related to smoking, coffee intake and physical activity. (1992 Dec)Hostmark ATScand J Soc Med
15061046Outcome of critical foot ischaemia in longstanding diabetic patients: a retrospective cohort study in a specialised tertiary care centre. (2004 Feb)Volaco AVasa
25998873Which role do midwives and gynecologists have in smoking cessation in pregnant women? - A study in Flanders, Belgium. (2015 Jun)De Wilde KSex Reprod Healthc
17541391Serum uric acid is associated with microvascular function in hypertensive individuals. (2007 Aug)de A Coutinho TJ Hum Hypertens
27686435[A clinical study of single subcortical cerebral infarction of middle cerebral artery territory]. (2016 Oct 1)Yang LZhonghua Nei Ke Za Zhi
27770044Methotrexate impact on radiographic progression in biologic-treated rheumatoid arthritis under clinical remission: A case report on monozygotic Caucasian twins. (2016 Dec)Soukup TInt J Immunopathol Pharmacol
9116423Young adults with alpha 1-antitrypsin deficiency identified neonatally: their health, knowledge about and adaptation to the high-risk condition. (1997 Jan)Sveger TActa Paediatr
23773646Risk factors for chronic low back pain in a sample of suburban Sri Lankan adult males. (2013 Apr)Karunanayake ALInt J Rheum Dis
15529576Hand abnormalities of the patients with diabetes mellitus. (2000-2001)Mota MRom J Intern Med
26273671GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective. (2015)Adela RJ Diabetes Res
17497516Knowledge, attitude, and practice of Nigerian commercial motorcyclists in the use of crash helmet and other safety measures. (2007 Jun)Oginni FOTraffic Inj Prev
740520[Femoral neck fracture treated by head arthroplasty: factors of life prognosis. 477 cases (author's transl)]. (1978 Nov 4)Katzner MNouv Presse Med
19346318PPARgamma activation extinguishes smoking carcinogen by inhibiting NNK-mediated proliferation. (2010 Jan)Li MYAm J Respir Cell Mol Biol
7881852[Role of carcinogenic polycyclic aromatic hydrocarbons in the etiology of lung cancer morbidity among the population a of a large industrial city]. (1994)Kireeva ISMed Tr Prom Ekol
11284428[Health status of the population in six cities in the Czech Republic: prevalence and therapy of various chronic diseases]. (2001 Mar 1)Gregurkova MCas Lek Cesk
11171478[Unstable angina in the elderly: clinical, profile, management and mortality at three months. The PEPA Registry Data]. (2000 Dec)Bermejo Garcia JRev Esp Cardiol
22889997You get old, you get breathless, and you die: chronic obstructive pulmonary disease in Barnsley, UK. (2012 Nov)Small NHealth Place
23026815Salivary hexosaminidase in smoking alcoholics with bad periodontal and dental states. (2013 Apr 1)Waszkiewicz NDrug Alcohol Depend
24586750The association between smoking and ectopic pregnancy: why nicotine is BAD for your fallopian tube. (2014)Horne AWPLoS One
9333372[Health status and medical care accessibility of single, homeless persons]. (1997 Jun)Trabert GGesundheitswesen
3213127[Alcoholism and resulting damage. 29th Bad Mergentheimer Liver and Metabolism Meeting. 9-11 October 1987. Proceedings]. (1988 Oct)-Z Gastroenterol
16167510Health lifestyles in Ukraine. (2005)Cockerham WCSoz Praventivmed
16881959Thrombin is bad, accepted; but is smoking good to prevent restenosis? (2006 Oct)Binder BRJ Thromb Haemost
22135122The effect of cigarette smoking on cancer treatment-related side effects. (2011)Peppone LJOncologist
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