| C552819 | 10-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate | 10-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate results in decreased phosphorylation of PTEN protein | 23001822 |
| C006718 | 1,12-benzoperylene | "1,12-benzoperylene results in decreased expression of PTEN mRNA" | 26377693 |
| C049325 | 1,2-dithiol-3-thione | "1,2-dithiol-3-thione results in decreased expression of PTEN mRNA" | 19162173 |
| C569670 | 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one | "[PTEN gene mutant form co-treated with PIK3CA gene mutant form] results in increased susceptibility to 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one" | 23136191 |
| C569670 | 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one | "PTEN gene mutant form results in increased susceptibility to 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one" | 23136191 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of PTEN protein modified form" | 21705713 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "CTNNB1 gene mutant form affects the susceptibility to [1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of PTEN protein]" | 21705713 |
| C097240 | 15-deoxy-delta(12,14)-prostaglandin J2 | "[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in increased expression of PTEN protein" | 16611854 |
| C513115 | 1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester | 1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester inhibits the reaction [VEGFA protein results in increased expression of PTEN protein] | 21769449 |
| C513115 | 1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester | 1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester results in increased expression of PTEN protein | 16806087 |
| C513115 | 1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester | "2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester inhibits the reaction [VEGFA protein results in increased expression of PTEN protein]]" | 21769449 |
| C513115 | 1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester | "2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester results in increased expression of PTEN protein]" | 16806087 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "Imatinib Mesylate promotes the reaction [PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]" | 23231951 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "PIK3CA gene mutant form promotes the reaction [PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form co-treated with PIK3CA gene mutant form] results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine" | 23136191 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "PTEN gene mutant form promotes the reaction [ERBB2 gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "PTEN gene mutant form promotes the reaction [PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine" | 20103642|2313619 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of AKT1 protein" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of EIF4EBP1 protein" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of FOXO1 protein" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of GSK3B protein" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of RPS6KB1 protein" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of RPS6 protein" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased cleavage of PARP1 protein" | 20453058 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "PTEN protein results in decreased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine" | 21994956 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | PTEN protein inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]] | 19808899 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | PTEN protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of CA9 protein]] | 19808899 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | PTEN protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 protein]] | 19808899 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | PTEN protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein]] | 19808899 |
| C019273 | 2,2-bis(4-glycidyloxyphenyl)propane | "2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester inhibits the reaction [VEGFA protein results in increased expression of PTEN protein]]" | 21769449 |
| C019273 | 2,2-bis(4-glycidyloxyphenyl)propane | "2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester results in increased expression of PTEN protein]" | 16806087 |
| C019273 | 2,2-bis(4-glycidyloxyphenyl)propane | "2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone results in increased expression of PTEN protein]" | 16806087 |
| C486182 | 2,3-bis(4-hydroxyphenyl)-propionitrile | "2,3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of PTEN protein" | 19264808 |
| C486182 | 2,3-bis(4-hydroxyphenyl)-propionitrile | "ESR1 protein affects the reaction [2,3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of PTEN protein]" | 19264808 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of PTEN mRNA" | 28433925 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | "2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of PTEN protein" | 24726520 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | [decitabine co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Sirolimus] results in increased expression of PTEN mRNA | 18622747 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | PTEN protein inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]] | 19808899 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | PTEN protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of CA9 protein]] | 19808899 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | PTEN protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 protein]] | 19808899 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | PTEN protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein]] | 19808899 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PTEN protein" | 22581815 |
| C570662 | 2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one | "2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one results in increased expression of PTEN protein" | 23639247 |
| C457499 | 2-chloro-5-nitrobenzanilide | "2-chloro-5-nitrobenzanilide inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased expression of PTEN protein]" | 28834734 |
| C457499 | 2-chloro-5-nitrobenzanilide | 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in increased expression of PTEN mRNA] | 17506947 |
| C457499 | 2-chloro-5-nitrobenzanilide | 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in increased expression of PTEN protein] | 17506947 |
| C457499 | 2-chloro-5-nitrobenzanilide | 2-chloro-5-nitrobenzanilide inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA] | 20578043 |
| C018855 | 2-tert-butylhydroquinone | PTEN protein affects the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] | 23829535 |
| C581004 | 3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile | "2-chloro-5-nitrobenzanilide inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased expression of PTEN protein]" | 28834734 |
| C581004 | 3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile | "3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased expression of PTEN protein" | 28834734 |
| C581004 | 3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile | "3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased expression of PTEN protein" | 28834734 |
| C486184 | 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol | "4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of PTEN protein" | 19264808 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTEN mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTEN mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Genistein results in increased expression of PTEN protein]" | 20673057 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTEN mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTEN mRNA" | 27188386 |
| C584755 | 6-bromo-8-ethoxy-3-nitro-2H-chromene | PTEN protein affects the susceptibility to 6-bromo-8-ethoxy-3-nitro-2H-chromene | 24831963 |
| C584755 | 6-bromo-8-ethoxy-3-nitro-2H-chromene | PTEN protein inhibits the reaction [6-bromo-8-ethoxy-3-nitro-2H-chromene results in increased cleavage of PARP1 protein] | 24831963 |
| C557120 | 8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene | PTEN protein affects the susceptibility to 8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene | 24831963 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [arsenic trioxide results in increased oxidation of PTEN protein] | 21097842 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 21195169 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein]] | 27022031 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 21195169 |
| D020106 | Acrylamide | Acrylamide results in decreased expression of PTEN mRNA | 28959563 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of PTEN gene | 27153756 |
| C031143 | AICA ribonucleotide | PTEN protein results in increased susceptibility to AICA ribonucleotide | 19625624 |
| C103303 | alitretinoin | "[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in increased expression of PTEN protein" | 16611854 |
| D013196 | Dihydrotestosterone | Dihydrotestosterone inhibits the reaction [resveratrol results in increased expression of PTEN mRNA] | 20729295 |
| D013196 | Dihydrotestosterone | Dihydrotestosterone results in decreased expression of PTEN mRNA | 20729295 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of PTEN mRNA | 16483693 |
| D000643 | Ammonium Chloride | Ammonium Chloride results in decreased expression of PTEN protein | 16483693 |
| D000900 | Anti-Bacterial Agents | Anti-Bacterial Agents inhibits the reaction [PTEN gene mutant form results in increased abundance of Lipopolysaccharides] | 27022031 |
| D000900 | Anti-Bacterial Agents | Anti-Bacterial Agents inhibits the reaction [PTEN gene mutant form results in increased secretion of GPT protein] | 27022031 |
| D000959 | Antihypertensive Agents | Antihypertensive Agents results in increased expression of PTEN mRNA | 15646324 |
| D000959 | Antihypertensive Agents | Antihypertensive Agents results in increased expression of PTEN protein | 15646324 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in increased expression of PTEN mRNA | 24449571 |
| D001151 | Arsenic | Arsenic results in decreased expression of PTEN protein | 25586904 |
| C006632 | arsenic trioxide | Acetylcysteine inhibits the reaction [arsenic trioxide results in increased oxidation of PTEN protein] | 21097842 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased activity of PTEN protein | 21097842 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased oxidation of PTEN protein | 21097842 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of PTEN mRNA | 23497375 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of PTEN mRNA | 22521957|2323900 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of PTEN protein | 20534739|2085725 |
| C006632 | arsenic trioxide | MAPK8 protein affects the reaction [arsenic trioxide results in increased expression of PTEN protein] | 20534739 |
| C006632 | arsenic trioxide | MIR19A inhibits the reaction [arsenic trioxide results in increased expression of PTEN protein] | 20857258 |
| C006632 | arsenic trioxide | PTEN protein promotes the reaction [arsenic trioxide results in decreased phosphorylation of WEE1 protein] | 22730174 |
| C006632 | arsenic trioxide | PTEN protein promotes the reaction [arsenic trioxide results in increased phosphorylation of CDK1 protein] | 22730174 |
| C006632 | arsenic trioxide | PTEN protein results in increased susceptibility to arsenic trioxide | 22185283 |
| C006632 | arsenic trioxide | pyrazolanthrone inhibits the reaction [arsenic trioxide results in increased expression of PTEN protein] | 20534739 |
| C006632 | arsenic trioxide | salvin promotes the reaction [arsenic trioxide results in increased expression of PTEN mRNA] | 23239002 |
| C015001 | arsenite | arsenite results in decreased expression of PTEN protein | 22387281 |
| C015001 | arsenite | RELA mutant form inhibits the reaction [arsenite results in decreased expression of PTEN protein] | 22387281 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite results in decreased expression of PTEN protein" | 21570478 |
| D000069059 | Atorvastatin Calcium | Atorvastatin Calcium results in increased expression of PTEN protein | 15837263 |
| D001374 | Azacitidine | Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA] | 22841775 |
| D001374 | Azacitidine | Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein] | 22841775 |
| D001374 | Azacitidine | Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter] | 22841775 |
| D001554 | Benzene | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of PTEN mRNA | 17905399 |
| C038198 | benzenesulfonamide | benzenesulfonamide analog results in decreased expression of PTEN | 22713211 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene metabolite results in increased expression of PTEN mRNA | 26314263 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene inhibits the reaction [AHR protein binds to PTEN promoter] | 19654925 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of PTEN mRNA | 20504355 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PTEN mRNA" | 19150397|2001819 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc Sulfate results in decreased stability of PTEN protein] | 20100827 |
| D004958 | Estradiol | ESR1 protein affects the reaction [Estradiol results in increased expression of PTEN mRNA] | 19264808 |
| D004958 | Estradiol | ESR1 protein affects the reaction [Estradiol results in increased expression of PTEN protein] | 19264808 |
| D004958 | Estradiol | ESR1 protein alternative form inhibits the reaction [Estradiol results in increased expression of PTEN mRNA] | 20302909 |
| D004958 | Estradiol | ESR1 protein alternative form inhibits the reaction [Estradiol results in increased expression of PTEN protein] | 20302909 |
| D004958 | Estradiol | [ESR2 protein results in increased susceptibility to Estradiol] which results in increased expression of PTEN protein | 21732360 |
| D004958 | Estradiol | Estradiol results in decreased expression of PTEN mRNA | 21890461 |
| D004958 | Estradiol | Estradiol results in increased expression of PTEN mRNA | 20302909 |
| D004958 | Estradiol | Estradiol results in increased expression of PTEN protein | 19264808|2030290 |
| D004958 | Estradiol | PTEN protein affects the reaction [Estradiol promotes the reaction [AKT1 protein modified form binds to IRS1 protein]] | 19435893 |
| D004958 | Estradiol | [Estradiol co-treated with Norepinephrine] results in decreased expression of PTEN mRNA | 16954335 |
| D004958 | Estradiol | Estradiol results in decreased expression of PTEN mRNA | 16954335 |
| C044887 | beta-methylcholine | beta-methylcholine affects the expression of PTEN mRNA | 21179406 |
| C053541 | bicalutamide | bicalutamide promotes the reaction [PTEN protein results in decreased expression of KLK3 mRNA] | 16637073 |
| C053541 | bicalutamide | bicalutamide results in increased activity of PTEN protein | 16637073 |
| C053541 | bicalutamide | [bicalutamide co-treated with resveratrol] results in increased expression of PTEN mRNA | 20729295 |
| C053541 | bicalutamide | bicalutamide results in increased expression of PTEN mRNA | 20729295 |
| D001663 | Bilirubin | Bilirubin inhibits the reaction [IL18 protein results in increased expression of PTEN protein] | 18215737 |
| D001664 | Biliverdine | Biliverdine inhibits the reaction [IL18 protein results in increased expression of PTEN protein] | 18215737 |
| C472777 | bisperoxovanadium | bisperoxovanadium analog promotes the reaction [TGFB1 protein results in decreased expression of PTEN protein] | 27818223 |
| C472777 | bisperoxovanadium | hesperetin analog inhibits the reaction [bisperoxovanadium analog promotes the reaction [TGFB1 protein results in decreased expression of PTEN protein]] | 27818223 |
| C006780 | bisphenol A | bisphenol A affects the expression of PTEN mRNA | 20170705 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of PTEN mRNA | 21890461 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of PTEN protein | 21890461 |
| C006780 | bisphenol A | bisphenol A results in increased expression of PTEN protein | 24831732 |
| C006780 | bisphenol A | bisphenol A results in increased phosphorylation of PTEN protein | 21890461 |
| C006780 | bisphenol A | Curcumin inhibits the reaction [bisphenol A results in increased expression of PTEN protein] | 24831732 |
| C006780 | bisphenol A | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PTEN mRNA | 28628672 |
| C006780 | bisphenol A | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of PTEN mRNA" | 28433925 |
| C006780 | bisphenol A | bisphenol A affects the expression of PTEN protein | 27296223 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of PTEN mRNA | 27296223|2753935 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of PTEN protein | 24884420 |
| C006780 | bisphenol A | bisphenol A results in increased expression of PTEN mRNA | 24464975|2518105 |
| C006780 | bisphenol A | bisphenol A results in increased expression of PTEN protein | 24464975 |
| C000611646 | bisphenol F | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PTEN mRNA | 28628672 |
| C005961 | bis(tri-n-butyltin)oxide | bis(tri-n-butyltin)oxide results in increased expression of PTEN mRNA | 24247028|2631426 |
| D019328 | Buthionine Sulfoximine | Buthionine Sulfoximine promotes the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D019328 | Buthionine Sulfoximine | Buthionine Sulfoximine promotes the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of PTEN mRNA | 15336504 |
| D002087 | Butyrates | Butyrates results in increased expression of PTEN mRNA | 16042588 |
| D002104 | Cadmium | Acetylcysteine inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D002104 | Cadmium | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D002104 | Cadmium | Buthionine Sulfoximine promotes the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D002104 | Cadmium | Cadmium results in increased ubiquitination of and results in increased degradation of and results in decreased expression of PTEN protein | 24449419 |
| D019256 | Cadmium Chloride | Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 21195169 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of PTEN mRNA | 25851441 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of PTEN protein | 21195169|2751046 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN results in decreased susceptibility to Cadmium Chloride | 21883094 |
| D019256 | Cadmium Chloride | Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D019256 | Cadmium Chloride | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D019256 | Cadmium Chloride | Buthionine Sulfoximine promotes the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein] | 24449419 |
| D019256 | Cadmium Chloride | Cadmium Chloride affects the expression of PTEN mRNA | 18974090 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased ubiquitination of and results in increased degradation of and results in decreased expression of PTEN protein | 24449419 |
| D019256 | Cadmium Chloride | Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 21195169 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of PTEN protein | 21195169|2411152 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased expression of CYBA protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased expression of CYBB protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased expression of NCF1 protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased expression of NCF4 protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN inhibits the reaction [Cadmium Chloride results in increased expression of RAC1 protein] | 21195169 |
| D019256 | Cadmium Chloride | PTEN protein inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein] | 24111524 |
| D019256 | Cadmium Chloride | PTEN protein inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] | 24111524 |
| D019256 | Cadmium Chloride | PTEN protein promotes the reaction [tripterine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]] | 24111524 |
| D019256 | Cadmium Chloride | PTEN protein promotes the reaction [tripterine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]] | 24111524 |
| D019256 | Cadmium Chloride | PTEN protein promotes the reaction [tripterine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]] | 24111524 |
| D019256 | Cadmium Chloride | Sirolimus inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 21195169 |
| D019256 | Cadmium Chloride | tripterine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 24111524 |
| D019256 | Cadmium Chloride | PTEN mutant form inhibits the reaction [Cadmium Chloride results in increased expression of MT2A mRNA] | 21883094 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of PTEN mRNA | 24752500 |
| D002248 | Carbon Monoxide | Carbon Monoxide inhibits the reaction [IL18 protein results in increased expression of PTEN protein] | 18215737 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of PTEN mRNA | 22841775|2781822 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of PTEN protein | 22841775|2781822 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased methylation of PTEN promoter | 22841775 |
| D002251 | Carbon Tetrachloride | hesperetin analog inhibits the reaction [Carbon Tetrachloride results in decreased expression of PTEN mRNA] | 27818223 |
| D002251 | Carbon Tetrachloride | hesperetin analog inhibits the reaction [Carbon Tetrachloride results in decreased expression of PTEN protein] | 27818223 |
| D017338 | Cladribine | Cholecalciferol promotes the reaction [Cladribine results in increased expression of PTEN mRNA] | 21801466 |
| D017338 | Cladribine | Cholecalciferol promotes the reaction [Cladribine results in increased methylation of PTEN promoter] | 21801466 |
| D017338 | Cladribine | Cladribine promotes the reaction [Cholecalciferol results in decreased methylation of PTEN promoter] | 21801466 |
| D017338 | Cladribine | Cladribine promotes the reaction [Cholecalciferol results in increased expression of PTEN mRNA] | 21801466 |
| D017338 | Cladribine | Cladribine results in decreased methylation of PTEN promoter | 21801466 |
| D017338 | Cladribine | Cladribine results in increased expression of PTEN mRNA | 21801466 |
| D017338 | Cladribine | resveratrol promotes the reaction [Cladribine results in decreased methylation of PTEN promoter] | 21801466 |
| D002791 | Cholesterol, Dietary | "Cholesterol, Dietary promotes the reaction [gossypetin results in increased expression of PTEN protein]" | 25622137 |
| D002794 | Choline | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PTEN gene | 20938992 |
| C039671 | ciglitazone | ciglitazone results in increased expression of PTEN protein | 20578043 |
| D002922 | Ciguatoxins | Ciguatoxins affects the expression of PTEN mRNA | 18353800 |
| C045645 | cilostazol | cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein] | 12807996 |
| C045645 | cilostazol | iberiotoxin inhibits the reaction [cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]] | 12807996 |
| C045645 | cilostazol | paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]] | 12807996 |
| C045645 | cilostazol | PTEN affects the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]] | 12807996 |
| C045645 | cilostazol | PTEN affects the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]] | 12807996 |
| C045645 | cilostazol | PTEN affects the reaction [iberiotoxin inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]]] | 12807996 |
| C045645 | cilostazol | PTEN affects the reaction [iberiotoxin inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]]] | 12807996 |
| C045645 | cilostazol | cilostazol results in decreased phosphorylation of PTEN protein | 15978173 |
| D004002 | Clodronic Acid | Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of CD68 mRNA] | 27022031 |
| D004002 | Clodronic Acid | Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of COL1A1 mRNA] | 27022031 |
| D004002 | Clodronic Acid | Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of IL6 mRNA] | 27022031 |
| D004002 | Clodronic Acid | Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TGFB1 mRNA] | 27022031 |
| D004002 | Clodronic Acid | Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TIMP1 mRNA] | 27022031 |
| D004002 | Clodronic Acid | Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TNF mRNA] | 27022031 |
| D004002 | Clodronic Acid | Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased secretion of GPT protein] | 27022031 |
| C007095 | cobaltiprotoporphyrin | cobaltiprotoporphyrin inhibits the reaction [IL18 protein results in increased expression of PTEN protein] | 18215737 |
| C018021 | cobaltous chloride | cobaltous chloride results in increased expression of PTEN mRNA | 19376846|2631426 |
| C018021 | cobaltous chloride | PTEN protein inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein] | 19808899 |
| C018021 | cobaltous chloride | PTEN protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of CA9 protein]] | 19808899 |
| C018021 | cobaltous chloride | PTEN protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 protein]] | 19808899 |
| C018021 | cobaltous chloride | PTEN protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of CA9 protein]] | 19808899 |
| C018021 | cobaltous chloride | PTEN protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 protein]] | 19808899 |
| C018021 | cobaltous chloride | cobaltous chloride results in increased expression of PTEN mRNA | 24386269 |
| D003042 | Cocaine | Cocaine affects the expression of PTEN mRNA | 15681117 |
| D003300 | Copper | [Copper co-treated with Disulfiram] results in decreased expression of PTEN protein | 20424113 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased expression of PTEN mRNA | 19549813 |
| D003345 | Corticosterone | Corticosterone results in increased phosphorylation of PTEN protein | 21647420 |
| D003375 | Coumestrol | Coumestrol results in decreased expression of PTEN mRNA | 19167446 |
| C102326 | cucurbitacin E | cucurbitacin E results in increased expression of and results in increased phosphorylation of PTEN protein | 27106530 |
| D003474 | Curcumin | Curcumin inhibits the reaction [bisphenol A results in increased expression of PTEN protein] | 24831732 |
| C057862 | cyanoginosin LR | cyanoginosin LR results in decreased expression of PTEN mRNA | 28062358 |
| C057862 | cyanoginosin LR | cyanoginosin LR results in decreased expression of PTEN protein | 28062358 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [Lovastatin results in increased expression of PTEN protein] | 16425225 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of PTEN protein] | 16425225 |
| D003561 | Cytarabine | PTEN protein results in increased susceptibility to Cytarabine | 22185283 |
| C531198 | dactolisib | PTEN gene mutant form results in increased susceptibility to dactolisib | 21372221 |
| D003630 | Daunorubicin | PTEN results in increased susceptibility to Daunorubicin | 21187093 |
| C014347 | decitabine | [decitabine affects the methylation of PTEN promoter] which affects the expression of PTEN mRNA | 18431742|1843174 |
| C014347 | decitabine | [decitabine co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Sirolimus] results in increased expression of PTEN mRNA | 18622747 |
| C014347 | decitabine | decitabine inhibits the reaction [sodium arsenite results in decreased expression of PTEN protein] | 26432159 |
| C014347 | decitabine | decitabine promotes the reaction [Tretinoin results in decreased methylation of PTEN promoter] | 21801466 |
| C014347 | decitabine | decitabine results in decreased methylation of PTEN gene | 21170675 |
| C014347 | decitabine | decitabine results in decreased methylation of PTEN promoter | 21801466 |
| C014347 | decitabine | decitabine results in increased expression of PTEN mRNA | 21170675|2180146 |
| C014347 | decitabine | Tretinoin promotes the reaction [decitabine results in decreased methylation of PTEN promoter] | 21801466 |
| C007262 | deoxynivalenol | deoxynivalenol results in increased expression of PTEN mRNA | 22846391 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PTEN mRNA | 28628672 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PTEN mRNA | 28628672 |
| D003907 | Dexamethasone | Dexamethasone inhibits the reaction [OVAL protein results in decreased expression of PTEN mRNA] | 25739523 |
| D003907 | Dexamethasone | Dexamethasone inhibits the reaction [OVAL protein results in decreased expression of PTEN protein] | 25739523 |
| D003976 | Diazinon | Diazinon results in increased methylation of PTEN gene | 22964155 |
| D003976 | Diazinon | Diazinon affects the expression of PTEN mRNA | 22546817 |
| C041517 | dibenzo(a,l)pyrene | "dibenzo(a,l)pyrene results in increased methylation of PTEN promoter" | 28476633 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased expression of PTEN mRNA | 21266533 |
| D002945 | Cisplatin | Cisplatin results in increased activity of PTEN protein | 11707646 |
| D002945 | Cisplatin | [MIR21 mRNA results in decreased susceptibility to Cisplatin] which results in decreased expression of PTEN mRNA | 23466500 |
| D002945 | Cisplatin | [MIR21 mRNA results in decreased susceptibility to Cisplatin] which results in decreased expression of PTEN protein | 23466500 |
| D002945 | Cisplatin | PTEN results in increased susceptibility to Cisplatin | 21116717 |
| D004008 | Diclofenac | Diclofenac affects the expression of PTEN mRNA | 24752500 |
| D004008 | Diclofenac | Diclofenac results in increased expression of PTEN mRNA | 26934552 |
| C000944 | dicrotophos | dicrotophos results in decreased expression of PTEN mRNA | 28302478 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of PTEN mRNA | 26548909 |
| D004041 | Dietary Fats | Dietary Fats results in increased expression of PTEN mRNA | 19030233 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in decreased expression of PTEN mRNA | 24804967 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in decreased expression of PTEN protein | 24804967 |
| D004051 | Diethylhexyl Phthalate | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of PTEN mRNA" | 28433925 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PTEN mRNA | 27048571 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in decreased expression of PTEN protein modified form | 19931519 |
| D004052 | Diethylnitrosamine | DMU-212 affects the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PTEN mRNA] | 27048571 |
| D004052 | Diethylnitrosamine | morin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein modified form] | 19931519 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in decreased expression of PTEN mRNA | 16804899 |
| D004178 | Diquat | Diquat affects the expression of PTEN mRNA | 22814884 |
| D004221 | Disulfiram | Disulfiram results in decreased expression of PTEN mRNA | 20530235 |
| D004221 | Disulfiram | [Copper co-treated with Disulfiram] results in decreased expression of PTEN protein | 20424113 |
| C558638 | DLBS 1425 | DLBS 1425 results in increased expression of PTEN protein | 20703095 |
| C521792 | DMU-212 | DMU-212 affects the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PTEN mRNA] | 27048571 |
| C521792 | DMU-212 | DMU-212 results in decreased expression of PTEN mRNA | 27048571 |
| D004317 | Doxorubicin | Doxorubicin affects the expression of PTEN mRNA | 26969377 |
| D004317 | Doxorubicin | [Doxorubicin co-treated with resveratrol] results in increased expression of PTEN mRNA | 26969377 |
| D004317 | Doxorubicin | [Doxorubicin co-treated with trichostatin A] results in increased expression of PTEN mRNA | 17330857 |
| D004317 | Doxorubicin | Doxorubicin results in increased activity of PTEN protein | 11707646 |
| D004317 | Doxorubicin | PTEN protein affects the susceptibility to [Doxorubicin co-treated with trichostatin A] | 17330857 |
| D004317 | Doxorubicin | PTEN protein inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of AKT1 protein] | 17935137 |
| D004317 | Doxorubicin | PTEN protein promotes the reaction [Doxorubicin results in decreased expression of AKT1 protein modified form] | 16438844 |
| D004317 | Doxorubicin | PTEN protein promotes the reaction [Doxorubicin results in decreased expression of BAD protein modified form] | 16438844 |
| D004317 | Doxorubicin | PTEN protein promotes the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein] | 17359293 |
| D004317 | Doxorubicin | PTEN protein promotes the reaction [Doxorubicin results in decreased phosphorylation of BAD protein] | 17359293 |
| D004317 | Doxorubicin | PTEN protein results in increased susceptibility to Doxorubicin | 16438844|1735929 |
| D004317 | Doxorubicin | PTEN results in increased susceptibility to Doxorubicin | 15548710 |
| D004317 | Doxorubicin | wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Doxorubicin] | 17935137 |
| D004791 | Enzyme Inhibitors | Enzyme Inhibitors inhibits the reaction [gossypetin results in increased expression of PTEN protein] | 25622137 |
| D004967 | Estrogens | [Estrogens co-treated with INS protein] inhibits the reaction [PTEN protein results in decreased expression of CCND1 protein] | 11230179 |
| D004967 | Estrogens | [Estrogens co-treated with INS protein] inhibits the reaction [PTEN protein results in increased expression of CDKN1B protein] | 11230179 |
| D004967 | Estrogens | Estrogens inhibits the reaction [PTEN protein results in increased expression of CDKN1B protein] | 11230179 |
| D000431 | Ethanol | Ethanol inhibits the reaction [IGF1 protein results in increased phosphorylation of PTEN protein] | 12700235 |
| D000431 | Ethanol | Ethanol inhibits the reaction [INS1 protein results in increased phosphorylation of PTEN protein] | 12700235 |
| D000431 | Ethanol | [Ethanol results in decreased susceptibility to INS1 protein] which results in increased activity of PTEN protein | 12700235 |
| D000431 | Ethanol | Ethanol results in increased expression of and results in increased activity of PTEN protein | 12700235 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol affects the expression of PTEN mRNA | 20170705|2686566 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTEN mRNA | 17942748 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of PTEN mRNA | 29097150 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in increased expression of PTEN mRNA | 23649840 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased mutagenesis of PTEN gene | 15755804|1672432 |
| D005047 | Etoposide | PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein] | 17935137 |
| D005047 | Etoposide | PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein] | 16807353 |
| D005047 | Etoposide | PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein] | 16807353 |
| D005047 | Etoposide | PTEN protein results in increased susceptibility to Etoposide | 17935137 |
| D005047 | Etoposide | wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Etoposide] | 17935137 |
| C574336 | excavatolide B | excavatolide B results in increased expression of PTEN protein | 26790859 |
| C028610 | flavanone | flavanone results in increased expression of PTEN protein | 22056764 |
| C024352 | fludarabine | fludarabine promotes the reaction [resveratrol results in decreased methylation of PTEN promoter] | 21801466 |
| C024352 | fludarabine | fludarabine promotes the reaction [Tretinoin results in decreased methylation of PTEN promoter] | 21801466 |
| C024352 | fludarabine | fludarabine results in decreased methylation of PTEN promoter | 21801466 |
| C024352 | fludarabine | fludarabine results in increased expression of PTEN mRNA | 21801466 |
| C024352 | fludarabine | resveratrol promotes the reaction [fludarabine results in decreased methylation of PTEN promoter] | 21801466 |
| C108339 | fludioxonil | fludioxonil results in decreased expression of PTEN mRNA | 23052036 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene results in decreased expression of PTEN protein | 19167416 |
| D005472 | Fluorouracil | Fluorouracil results in decreased expression of PTEN mRNA | 17039268 |
| D005485 | Flutamide | Flutamide results in increased expression of PTEN mRNA | 24136188 |
| D005492 | Folic Acid | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PTEN gene | 20938992 |
| D005557 | Formaldehyde | Formaldehyde results in increased expression of PTEN mRNA | 23649840 |
| D005632 | Fructose | Fructose results in increased expression of PTEN protein | 26358169 |
| D005632 | Fructose | tributylhexadecylphosphonium bromide inhibits the reaction [Fructose results in increased expression of PTEN protein] | 26358169 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Quercetin results in increased expression of PTEN protein] | 21732360 |
| C070081 | fulvestrant | PTEN protein results in increased susceptibility to fulvestrant | 19435893 |
| D005707 | Gallic Acid | Gallic Acid results in increased secretion of PTEN protein | 26530725 |
| C056507 | gemcitabine | gemcitabine affects the expression of PTEN mRNA | 17039268 |
| D019833 | Genistein | "(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Genistein results in increased expression of PTEN protein]" | 20673057 |
| D019833 | Genistein | Genistein affects the expression of PTEN mRNA | 18431742|2686566 |
| D019833 | Genistein | Genistein affects the expression of PTEN protein | 18431742 |
| D019833 | Genistein | Genistein inhibits the reaction [HIST3H3 protein modified form binds to PTEN promoter] | 18431742 |
| D019833 | Genistein | Genistein results in increased expression of PTEN mRNA | 15829497 |
| D019833 | Genistein | Genistein results in increased expression of PTEN protein | 15829497|2067305 |
| D019833 | Genistein | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased activity of FOXO3 protein | 18431742 |
| D019833 | Genistein | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein | 18431742 |
| D019833 | Genistein | PTEN protein results in increased susceptibility to Genistein | 20673057 |
| D019833 | Genistein | Genistein results in decreased expression of PTEN mRNA | 21048042 |
| C002963 | geranylgeranyl pyrophosphate | geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA] | 20578043 |
| D005947 | Glucose | [Glucose co-treated with INS protein] results in increased expression of PTEN protein | 18303120 |
| D005947 | Glucose | [Sirolimus results in decreased activity of MTOR protein] inhibits the reaction [[Glucose co-treated with INS protein] results in increased expression of PTEN protein] | 18303120 |
| C059922 | gossypetin | Enzyme Inhibitors inhibits the reaction [gossypetin results in increased expression of PTEN protein] | 25622137 |
| C059922 | gossypetin | gossypetin results in increased expression of PTEN protein | 25622137 |
| C059922 | gossypetin | "Cholesterol, Dietary promotes the reaction [gossypetin results in increased expression of PTEN protein]" | 25622137 |
| C059922 | gossypetin | gossypetin results in increased expression of PTEN protein | 25622137 |
| D006427 | Hemin | Hemin inhibits the reaction [IL18 protein results in increased expression of PTEN protein] | 18215737 |
| C013015 | hesperetin | hesperetin analog inhibits the reaction [bisperoxovanadium analog promotes the reaction [TGFB1 protein results in decreased expression of PTEN protein]] | 27818223 |
| C013015 | hesperetin | hesperetin analog inhibits the reaction [Carbon Tetrachloride results in decreased expression of PTEN mRNA] | 27818223 |
| C013015 | hesperetin | hesperetin analog inhibits the reaction [Carbon Tetrachloride results in decreased expression of PTEN protein] | 27818223 |
| C013015 | hesperetin | hesperetin analog inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA] | 27818223 |
| C013015 | hesperetin | hesperetin analog inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein] | 27818223 |
| C013015 | hesperetin | PTEN protein promotes the reaction [hesperetin analog inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]] | 27818223 |
| D017313 | Fenretinide | Fenretinide results in decreased expression of PTEN mRNA | 28973697 |
| D006835 | Hydrazones | Hydrazones results in increased expression of PTEN protein | 22056764 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased oxidation of and results in decreased activity of PTEN protein | 11916965 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in decreased expression of PTEN protein | 27494022 |
| D006861 | Hydrogen Peroxide | PI103 inhibits the reaction [Hydrogen Peroxide results in decreased expression of PTEN protein] | 27494022 |
| D006861 | Hydrogen Peroxide | PTEN gene mutant form results in increased abundance of Hydrogen Peroxide | 27022031 |
| D006861 | Hydrogen Peroxide | Quercetin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PTEN protein] | 27494022 |
| C014290 | hydroxyflutamide | hydroxyflutamide promotes the reaction [Testosterone results in increased phosphorylation of PTEN protein] | 26437446 |
| C014290 | hydroxyflutamide | hydroxyflutamide results in increased phosphorylation of PTEN protein | 26437446 |
| C064719 | iberiotoxin | iberiotoxin inhibits the reaction [cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]] | 12807996 |
| C064719 | iberiotoxin | PTEN affects the reaction [iberiotoxin inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]]] | 12807996 |
| C064719 | iberiotoxin | PTEN affects the reaction [iberiotoxin inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]]] | 12807996 |
| D000068877 | Imatinib Mesylate | "Imatinib Mesylate promotes the reaction [PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]" | 23231951 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PTEN mRNA | 28628672 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PTEN mRNA | 28628672 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PTEN mRNA | 25613284 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PTEN mRNA | 28628672 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PTEN mRNA | 28628672 |
| D007545 | Isoproterenol | Isoproterenol results in increased expression of PTEN mRNA | 20003209 |
| D007545 | Isoproterenol | Isoproterenol results in increased expression of PTEN mRNA | 16188065 |
| D007545 | Isoproterenol | Isoproterenol results in increased expression of PTEN protein | 16188065 |
| C544151 | jinfukang | jinfukang results in decreased expression of PTEN mRNA | 27392435 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in increased expression of PTEN mRNA | 25961927 |
| D007854 | Lead | Lead affects the expression of PTEN mRNA | 28903495 |
| C045463 | leflunomide | leflunomide results in increased expression of PTEN mRNA | 28988120 |
| C002385 | linsidomine | linsidomine results in increased oxidation of PTEN protein | 17302912 |
| C482199 | lipopolysaccharide, E coli O55-B5 | "[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTEN mRNA" | 18930950 |
| D008070 | Lipopolysaccharides | Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein]] | 27022031 |
| D008070 | Lipopolysaccharides | Anti-Bacterial Agents inhibits the reaction [PTEN gene mutant form results in increased abundance of Lipopolysaccharides] | 27022031 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein] | 27022031 |
| D008070 | Lipopolysaccharides | PTEN gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] | 27022031 |
| D008070 | Lipopolysaccharides | PTEN gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] | 27022031 |
| D008070 | Lipopolysaccharides | PTEN gene mutant form promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein] | 27022031 |
| D008070 | Lipopolysaccharides | PTEN gene mutant form promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] | 27022031 |
| D008070 | Lipopolysaccharides | PTEN gene mutant form results in increased abundance of Lipopolysaccharides | 27022031 |
| D008148 | Lovastatin | Cycloheximide inhibits the reaction [Lovastatin results in increased expression of PTEN protein] | 16425225 |
| D008148 | Lovastatin | Lovastatin results in increased expression of PTEN protein | 16425225 |
| D008148 | Lovastatin | PPARG protein affects the reaction [Lovastatin results in increased expression of PTEN protein] | 16425225 |
| D008148 | Lovastatin | Lovastatin results in increased expression of PTEN protein | 16425225 |
| D008148 | Lovastatin | PPARG affects the reaction [Lovastatin results in increased expression of PTEN protein] | 16425225 |
| D008148 | Lovastatin | 2-chloro-5-nitrobenzanilide inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA] | 20578043 |
| D008148 | Lovastatin | geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA] | 20578043 |
| D008148 | Lovastatin | Lovastatin results in increased expression of and results in increased phosphorylation of PTEN protein | 20578043 |
| D008148 | Lovastatin | Lovastatin results in increased expression of PTEN mRNA | 20578043 |
| D008148 | Lovastatin | PTEN protein affects the reaction [Lovastatin results in increased expression of MBP mRNA] | 20578043 |
| D008148 | Lovastatin | PTEN protein affects the reaction [Lovastatin results in increased expression of SOX10 mRNA] | 20578043 |
| C010480 | lupeol | lupeol results in increased expression of PTEN protein | 20979057 |
| C010480 | lupeol | PTEN protein results in increased susceptibility to lupeol | 20979057 |
| D008315 | Malondialdehyde | PTEN mutant form results in increased abundance of Malondialdehyde | 26548909 |
| D008627 | Mercuric Chloride | Mercuric Chloride results in decreased expression of PTEN mRNA | 27188386 |
| D008687 | Metformin | Metformin inhibits the reaction [Testosterone results in decreased expression of PTEN mRNA] | 26492952 |
| D008694 | Methamphetamine | Methamphetamine results in increased expression of PTEN mRNA | 19564919 |
| D008715 | Methionine | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PTEN gene | 20938992 |
| D008727 | Methotrexate | Methotrexate results in increased expression of PTEN mRNA | 17400583 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of PTEN mRNA | 26272509|2800136 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of PTEN mRNA | 28001369 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of PTEN protein modified form | 28821999 |
| C030957 | methylmercury II | methylmercury II results in increased expression of PTEN mRNA | 26314263 |
| C030957 | methylmercury II | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of PTEN mRNA | 17905399 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in increased expression of PTEN mRNA | 23649840 |
| D018817 | N-Methyl-3,4-methylenedioxyamphetamine | "N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of PTEN mRNA" | 20188158 |
| D008769 | Methylnitronitrosoguanidine | PTEN protein results in decreased susceptibility to Methylnitronitrosoguanidine | 20530668 |
| D008770 | Methylnitrosourea | Methylnitrosourea results in decreased expression of PTEN mRNA | 16616109 |
| C008493 | methylselenic acid | methylselenic acid results in increased expression of PTEN mRNA | 12517777 |
| C043243 | methyl tert-butyl ether | methyl tert-butyl ether affects the expression of PTEN mRNA | 24128854 |
| D008777 | Methyltestosterone | Methyltestosterone results in decreased expression of PTEN mRNA | 29191790 |
| D015741 | Metribolone | PTEN protein results in decreased susceptibility to Metribolone | 16637073 |
| C020300 | monomethylarsonic acid | monomethylarsonic acid results in decreased expression of PTEN mRNA | 24091636 |
| C020300 | monomethylarsonic acid | monomethylarsonic acid results in decreased expression of PTEN mRNA | 24091636 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid promotes the reaction [NFKB1 protein binds to PTEN promoter] | 28823542 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in decreased expression of PTEN mRNA | 28823542 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in decreased expression of PTEN protein | 28823542 |
| C008548 | morin | morin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein modified form] | 19931519 |
| C451426 | N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide | "N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of PTEN mRNA" | 23052036 |
| C539427 | N-(3-((2-hydroxynaphthalen-1-ylmethylene)amino)phenyl)-2-phenylpropionamide | N-(3-((2-hydroxynaphthalen-1-ylmethylene)amino)phenyl)-2-phenylpropionamide results in decreased expression of PTEN protein | 25739523 |
| C539427 | N-(3-((2-hydroxynaphthalen-1-ylmethylene)amino)phenyl)-2-phenylpropionamide | resveratrol inhibits the reaction [N-(3-((2-hydroxynaphthalen-1-ylmethylene)amino)phenyl)-2-phenylpropionamide results in decreased expression of PTEN protein] | 25739523 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon analog results in decreased expression of PTEN mRNA" | 25554681 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in decreased expression of PTEN mRNA" | 25620056 |
| C017096 | n-butoxyethanol | n-butoxyethanol results in decreased expression of PTEN mRNA | 19812364 |
| C051752 | nefazodone | nefazodone results in increased expression of PTEN mRNA | 24136188 |
| C022838 | nickel chloride | nickel chloride results in increased expression of PTEN mRNA | 17312168 |
| C029938 | nickel sulfate | nickel sulfate results in increased expression of PTEN mRNA | 16780908 |
| D009538 | Nicotine | Nicotine results in increased expression of PTEN mRNA | 11478936 |
| C025256 | nonylphenol | nonylphenol results in decreased expression of PTEN protein | 27832966 |
| C025256 | nonylphenol | nonylphenol results in increased expression of PTEN mRNA | 27832966 |
| C025256 | nonylphenol | wortmannin inhibits the reaction [nonylphenol results in decreased expression of PTEN protein] | 27832966 |
| D009638 | Norepinephrine | [Estradiol co-treated with Norepinephrine] results in decreased expression of PTEN mRNA | 16954335 |
| D009638 | Norepinephrine | Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PTEN mRNA] | 16954335 |
| D009638 | Norepinephrine | [Progesterone co-treated with Norepinephrine] results in increased expression of PTEN mRNA | 16954335 |
| C025589 | ochratoxin A | ochratoxin A metabolite results in increased expression of PTEN mRNA | 26314263 |
| C025589 | ochratoxin A | ochratoxin A results in decreased expression of PTEN mRNA | 19287073 |
| C025589 | ochratoxin A | ochratoxin A results in decreased phosphorylation of PTEN protein | 25002221 |
| C025589 | ochratoxin A | ochratoxin A results in increased expression of PTEN mRNA | 26314263 |
| D009828 | Oleanolic Acid | Oleanolic Acid results in increased expression of PTEN protein | 20726234 |
| C000594117 | ON123300 | PTEN protein inhibits the reaction [ON123300 results in increased phosphorylation of MAPK1 protein] | 24568969 |
| C000594117 | ON123300 | PTEN protein inhibits the reaction [ON123300 results in increased phosphorylation of MAPK3 protein] | 24568969 |
| D010100 | Oxygen | PTEN protein inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]] | 19808899 |
| D010100 | Oxygen | PTEN protein inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]] | 19808899 |
| D010100 | Oxygen | PTEN protein inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein] | 19808899 |
| D010100 | Oxygen | PTEN protein inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA] | 19808899 |
| D010100 | Oxygen | PTEN protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein]] | 19808899 |
| D010100 | Oxygen | PTEN protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein]] | 19808899 |
| D010100 | Oxygen | PTEN protein results in decreased susceptibility to Oxygen deficiency | 21994956 |
| D010100 | Oxygen | Oxygen deficiency results in decreased expression of PTEN protein | 19520921 |
| D010100 | Oxygen | rosiglitazone inhibits the reaction [Oxygen deficiency results in decreased expression of PTEN protein] | 19520921 |
| D017239 | Paclitaxel | Paclitaxel results in increased activity of PTEN protein | 11707646 |
| D017239 | Paclitaxel | PTEN results in increased susceptibility to Paclitaxel | 15548710 |
| C533469 | palomid 529 | PTEN protein results in decreased susceptibility to palomid 529 | 21551258 |
| D010261 | Paraoxon | Paraoxon results in increased expression of PTEN mRNA | 17223147 |
| D052638 | Particulate Matter | Particulate Matter results in increased phosphorylation of PTEN protein | 21818627 |
| C048220 | paxilline | paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]] | 12807996 |
| D010433 | Pentylenetetrazole | [Pentylenetetrazole co-treated with Vigabatrin] affects the expression of PTEN mRNA | 21503142 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in increased expression of PTEN mRNA | 23978341 |
| D030421 | Peroxynitrous Acid | Peroxynitrous Acid results in increased oxidation of PTEN protein | 17302912 |
| D010578 | Petroleum | Petroleum affects the expression of PTEN mRNA | 25208076 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of PTEN mRNA | 23091169 |
| D010634 | Phenobarbital | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PTEN mRNA | 27048571 |
| D010634 | Phenobarbital | DMU-212 affects the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PTEN mRNA] | 27048571 |
| D010713 | Phosphatidylcholines | PTEN protein binds to Phosphatidylcholines | 15313215 |
| D010713 | Phosphatidylcholines | [TXN protein binds to PTEN protein] inhibits the reaction [PTEN protein binds to Phosphatidylcholines] | 15313215 |
| C483858 | phosphatidylethanolamine | PTEN protein binds to phosphatidylethanolamine | 15313215 |
| C483858 | phosphatidylethanolamine | [TXN protein binds to PTEN protein] inhibits the reaction [PTEN protein binds to phosphatidylethanolamine] | 15313215 |
| C060974 | phosphatidylinositol 3,4,5-triphosphate | "PTEN protein affects the abundance of phosphatidylinositol 3,4,5-triphosphate" | 21097842 |
| C060974 | phosphatidylinositol 3,4,5-triphosphate | "PTEN protein results in decreased phosphorylation of and results in increased activity of phosphatidylinositol 3,4,5-triphosphate" | 12888921 |
| C060974 | phosphatidylinositol 3,4,5-triphosphate | "PTEN protein results in decreased phosphorylation of phosphatidylinositol 3,4,5-triphosphate" | 18303120 |
| C060974 | phosphatidylinositol 3,4,5-triphosphate | "PTEN protein results in increased hydrolysis of and results in decreased activity of phosphatidylinositol 3,4,5-triphosphate" | 15313215 |
| D010718 | Phosphatidylserines | PTEN protein binds to Phosphatidylserines | 15313215 |
| D010718 | Phosphatidylserines | [TXN protein binds to PTEN protein] inhibits the reaction [PTEN protein binds to Phosphatidylserines] | 15313215 |
| C003121 | phosphinothricin | phosphinothricin affects the expression of PTEN mRNA | 25477793 |
| C522973 | PI103 | PI103 inhibits the reaction [Hydrogen Peroxide results in decreased expression of PTEN protein] | 27494022 |
| D010862 | Pilocarpine | PTEN protein mutant form inhibits the reaction [Pilocarpine results in increased activity of NGFR protein] | 21084616 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of PTEN mRNA | 20813756 |
| C035988 | procymidone | procymidone results in increased expression of PTEN mRNA | 15686871 |
| D011374 | Progesterone | Progesterone affects the expression of PTEN mRNA | 17251523 |
| D011374 | Progesterone | [Progesterone co-treated with Norepinephrine] results in increased expression of PTEN mRNA | 16954335 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [arsenic trioxide results in increased expression of PTEN protein] | 20534739 |
| C031280 | pyrazole | pyrazole results in decreased expression of PTEN mRNA | 17945193 |
| D011794 | Quercetin | [ESR2 protein results in increased susceptibility to Quercetin] which results in increased expression of PTEN protein | 21732360 |
| D011794 | Quercetin | fulvestrant inhibits the reaction [Quercetin results in increased expression of PTEN protein] | 21732360 |
| D011794 | Quercetin | Quercetin results in increased expression of PTEN mRNA | 14715546|1582949 |
| D011794 | Quercetin | Quercetin results in increased expression of PTEN protein | 15829497|2173236 |
| D011794 | Quercetin | Quercetin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PTEN protein] | 27494022 |
| D011794 | Quercetin | Quercetin results in increased expression of PTEN mRNA | 18095365 |
| D017382 | Reactive Oxygen Species | Reactive Oxygen Species results in decreased expression of PTEN mRNA | 25800948 |
| C059514 | resveratrol | [Doxorubicin co-treated with resveratrol] results in increased expression of PTEN mRNA | 26969377 |
| C059514 | resveratrol | fludarabine promotes the reaction [resveratrol results in decreased methylation of PTEN promoter] | 21801466 |
| C059514 | resveratrol | PTEN protein affects the reaction [resveratrol results in decreased phosphorylation of AKT1 protein] | 26530632 |
| C059514 | resveratrol | PTEN protein promotes the reaction [resveratrol results in decreased phosphorylation of MTOR protein] | 21168265 |
| C059514 | resveratrol | resveratrol inhibits the reaction [N-(3-((2-hydroxynaphthalen-1-ylmethylene)amino)phenyl)-2-phenylpropionamide results in decreased expression of PTEN protein] | 25739523 |
| C059514 | resveratrol | resveratrol promotes the reaction [Cladribine results in decreased methylation of PTEN promoter] | 21801466 |
| C059514 | resveratrol | resveratrol promotes the reaction [fludarabine results in decreased methylation of PTEN promoter] | 21801466 |
| C059514 | resveratrol | [resveratrol results in decreased activity of AR protein] which results in increased expression of PTEN mRNA | 20729295 |
| C059514 | resveratrol | resveratrol results in decreased expression of PTEN mRNA | 22971900 |
| C059514 | resveratrol | resveratrol results in decreased methylation of PTEN promoter | 21801466 |
| C059514 | resveratrol | resveratrol results in decreased phosphorylation of PTEN protein | 26530632 |
| C059514 | resveratrol | resveratrol results in increased activity of PTEN protein | 24812624 |
| C059514 | resveratrol | resveratrol results in increased expression of PTEN mRNA | 15829497|2180146 |
| C059514 | resveratrol | resveratrol results in increased expression of PTEN protein | 15829497|2063773 |
| C059514 | resveratrol | resveratrol inhibits the reaction [OVAL protein results in decreased expression of PTEN mRNA] | 25739523 |
| C059514 | resveratrol | resveratrol inhibits the reaction [OVAL protein results in decreased expression of PTEN protein] | 25739523 |
| C059514 | resveratrol | resveratrol results in increased phosphorylation of PTEN protein | 22363816 |
| C059514 | resveratrol | [bicalutamide co-treated with resveratrol] results in increased expression of PTEN mRNA | 20729295 |
| C059514 | resveratrol | Dihydrotestosterone inhibits the reaction [resveratrol results in increased expression of PTEN mRNA] | 20729295 |
| C059514 | resveratrol | PTEN protein mutant form results in decreased susceptibility to resveratrol | 21179458 |
| C059514 | resveratrol | PTEN protein results in increased susceptibility to resveratrol | 21179458 |
| C059514 | resveratrol | resveratrol results in increased expression of PTEN mRNA | 20729295 |
| C089730 | rosiglitazone | "2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone results in increased expression of PTEN protein]" | 16806087 |
| C089730 | rosiglitazone | 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in increased expression of PTEN mRNA] | 17506947 |
| C089730 | rosiglitazone | 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in increased expression of PTEN protein] | 17506947 |
| C089730 | rosiglitazone | Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of PTEN protein] | 16425225 |
| C089730 | rosiglitazone | PPARG protein affects the reaction [rosiglitazone results in increased expression of PTEN protein] | 16425225 |
| C089730 | rosiglitazone | PTEN mRNA affects the reaction [rosiglitazone results in decreased phosphorylation of AKT1 protein] | 17506947 |
| C089730 | rosiglitazone | PTEN mRNA affects the susceptibility to rosiglitazone | 16775433 |
| C089730 | rosiglitazone | rosiglitazone results in increased expression of PTEN mRNA | 12670479|1677543 |
| C089730 | rosiglitazone | rosiglitazone results in increased expression of PTEN protein | 12670479|1642522 |
| C089730 | rosiglitazone | PPARG affects the reaction [rosiglitazone results in increased expression of PTEN protein] | 16425225 |
| C089730 | rosiglitazone | rosiglitazone inhibits the reaction [Oxygen deficiency results in decreased expression of PTEN protein] | 19520921 |
| C089730 | rosiglitazone | rosiglitazone results in increased expression of PTEN protein | 16425225 |
| D012402 | Rotenone | Rotenone results in decreased expression of PTEN mRNA | 26806867 |
| C018381 | salvin | salvin promotes the reaction [arsenic trioxide results in increased expression of PTEN mRNA] | 23239002 |
| C018381 | salvin | salvin results in increased expression of PTEN mRNA | 23239002 |
| C093642 | SB 203580 | SB 203580 inhibits the reaction [IL18 protein results in increased expression of PTEN mRNA] | 18215737 |
| D012715 | Sesame Oil | Sesame Oil results in increased expression of PTEN mRNA | 29191790 |
| D019821 | Simvastatin | Simvastatin results in increased expression of PTEN mRNA | 20060890 |
| D019821 | Simvastatin | Simvastatin results in increased expression of PTEN protein | 20060890 |
| D020123 | Sirolimus | [decitabine co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Sirolimus] results in increased expression of PTEN mRNA | 18622747 |
| D020123 | Sirolimus | PTEN protein results in decreased susceptibility to Sirolimus | 19625624 |
| D020123 | Sirolimus | Sirolimus results in decreased expression of PTEN protein | 18303120 |
| D020123 | Sirolimus | Sirolimus inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 21195169 |
| D020123 | Sirolimus | [Sirolimus results in decreased activity of MTOR protein] inhibits the reaction [[Glucose co-treated with INS protein] results in increased expression of PTEN protein] | 18303120 |
| C009277 | sodium arsenate | sodium arsenate results in increased expression of PTEN mRNA | 21795629 |
| C009277 | sodium arsenate | sodium arsenate results in decreased expression of PTEN mRNA | 14713550 |
| C009277 | sodium arsenate | sodium arsenate results in decreased expression of PTEN protein | 14713550 |
| C017947 | sodium arsenite | decitabine inhibits the reaction [sodium arsenite results in decreased expression of PTEN protein] | 26432159 |
| C017947 | sodium arsenite | MIR21 mRNA affects the reaction [sodium arsenite results in decreased expression of PTEN protein] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in decreased expression of MTOR protein]] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased expression of BECN1 protein]] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased expression of MAP1LC3B protein]] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased phosphorylation of MAPK1 protein]] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased phosphorylation of MAPK3 protein]] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [sodium arsenite results in decreased expression of MTOR protein] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [sodium arsenite results in increased expression of BECN1 protein] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [sodium arsenite results in increased phosphorylation of MAPK1 protein] | 27107786 |
| C017947 | sodium arsenite | PTEN protein affects the reaction [sodium arsenite results in increased phosphorylation of MAPK3 protein] | 27107786 |
| C017947 | sodium arsenite | sodium arsenite affects the methylation of PTEN gene | 28589171 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of PTEN mRNA | 20056578|2406803 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of PTEN protein | 24431212|2580488 |
| C017947 | sodium arsenite | U 0126 inhibits the reaction [sodium arsenite results in decreased expression of PTEN protein] | 26432159 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of PTEN mRNA | 16014739 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of PTEN protein | 26432159 |
| D012969 | Sodium Fluoride | Sodium Fluoride results in increased expression of PTEN mRNA | 21340527 |
| D013012 | Sorbitol | Sorbitol affects the localization of PTEN protein | 16807353 |
| D013012 | Sorbitol | Sorbitol affects the localization of PTEN protein | 16807353 |
| D013012 | Sorbitol | Sorbitol affects the localization of PTEN protein | 16807353 |
| C473478 | sunitinib | PTEN protein inhibits the reaction [sunitinib results in increased expression of and results in increased secretion of CXCL8 protein] | 22532600 |
| C473478 | sunitinib | PTEN protein inhibits the reaction [sunitinib results in increased expression of and results in increased secretion of IL6 protein] | 22532600 |
| C473478 | sunitinib | PTEN protein results in increased susceptibility to sunitinib | 22532600 |
| D000952 | Antigens, Polyomavirus Transforming | "Antigens, Polyomavirus Transforming results in decreased expression of PTEN mRNA" | 26680231 |
| D013629 | Tamoxifen | PTEN protein results in increased susceptibility to Tamoxifen | 19435893 |
| D013739 | Testosterone | hydroxyflutamide promotes the reaction [Testosterone results in increased phosphorylation of PTEN protein] | 26437446 |
| D013739 | Testosterone | Metformin inhibits the reaction [Testosterone results in decreased expression of PTEN mRNA] | 26492952 |
| D013739 | Testosterone | Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PTEN mRNA] | 16954335 |
| D013739 | Testosterone | Testosterone results in decreased expression of PTEN mRNA | 16954335|2649295 |
| D013739 | Testosterone | Testosterone results in increased phosphorylation of PTEN protein | 26437446 |
| C020806 | tetrabromobisphenol A | tetrabromobisphenol A results in decreased expression of PTEN mRNA | 28970181 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of PTEN mRNA | 17101203 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased phosphorylation of PTEN protein | 27312872 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of PTEN mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of PTEN mRNA" | 28433925 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTEN mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin inhibits the reaction [AHR protein binds to PTEN promoter] | 19654925 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of PTEN mRNA | 18796159 |
| D013752 | Tetracycline | Tetracycline results in increased expression of PTEN mRNA | 16917069 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PTEN mRNA | 25613284 |
| C504718 | TGX 221 | PTEN gene mutant form results in increased susceptibility to TGX 221 analog | 22588880 |
| C504718 | TGX 221 | [PTEN gene mutant form results in increased susceptibility to TGX 221 analog] which results in decreased phosphorylation of AKT1 protein | 22588880 |
| D013792 | Thalidomide | Thalidomide results in increased expression of PTEN protein | 19567134 |
| D013893 | Thiram | Thiram results in decreased expression of PTEN mRNA | 20530235 |
| C009495 | titanium dioxide | titanium dioxide results in decreased expression of PTEN mRNA | 29128614 |
| D014051 | Toluene 2,4-Diisocyanate | "PTEN protein inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL17A mRNA]" | 17982072 |
| D014051 | Toluene 2,4-Diisocyanate | "PTEN protein inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL17A protein]" | 17982072 |
| D014051 | Toluene 2,4-Diisocyanate | "PTEN protein inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of RELA protein]" | 17982072 |
| D014051 | Toluene 2,4-Diisocyanate | "Toluene 2,4-Diisocyanate results in decreased expression of and results in decreased activity of PTEN protein" | 17982072 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of PTEN mRNA | 20530235 |
| D014212 | Tretinoin | decitabine promotes the reaction [Tretinoin results in decreased methylation of PTEN promoter] | 21801466 |
| D014212 | Tretinoin | fludarabine promotes the reaction [Tretinoin results in decreased methylation of PTEN promoter] | 21801466 |
| D014212 | Tretinoin | [Tretinoin co-treated with IFNG protein] results in increased expression of PTEN protein | 17960384 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [decitabine results in decreased methylation of PTEN promoter] | 21801466 |
| D014212 | Tretinoin | Tretinoin results in decreased methylation of PTEN promoter | 21801466 |
| D014212 | Tretinoin | Tretinoin results in increased expression of PTEN mRNA | 23724009 |
| C575594 | tributylhexadecylphosphonium bromide | tributylhexadecylphosphonium bromide inhibits the reaction [Fructose results in increased expression of PTEN protein] | 26358169 |
| C011559 | tributyltin | tributyltin results in increased expression of PTEN mRNA | 26314263 |
| D014241 | Trichloroethylene | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of PTEN mRNA | 17905399 |
| D014241 | Trichloroethylene | Trichloroethylene results in increased expression of PTEN mRNA | 19448997 |
| C012589 | trichostatin A | [Doxorubicin co-treated with trichostatin A] results in increased expression of PTEN mRNA | 17330857 |
| C012589 | trichostatin A | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTEN mRNA" | 27188386 |
| C012589 | trichostatin A | PTEN protein affects the susceptibility to [Doxorubicin co-treated with trichostatin A] | 17330857 |
| C012589 | trichostatin A | trichostatin A promotes the reaction [[EP300 protein co-treated with EGR1 protein] results in increased expression of PTEN mRNA] | 17330857 |
| C012589 | trichostatin A | trichostatin A promotes the reaction [HIST3H3 protein modified form binds to PTEN promoter] | 17330857 |
| C012589 | trichostatin A | trichostatin A promotes the reaction [HIST4H4 protein modified form binds to PTEN promoter] | 17330857 |
| C012589 | trichostatin A | trichostatin A results in increased expression of PTEN mRNA | 17330857|2493525 |
| C012589 | trichostatin A | trichostatin A results in increased expression of PTEN protein | 17330857 |
| C050414 | tripterine | PTEN protein promotes the reaction [tripterine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]] | 24111524 |
| C050414 | tripterine | PTEN protein promotes the reaction [tripterine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]] | 24111524 |
| C050414 | tripterine | PTEN protein promotes the reaction [tripterine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]] | 24111524 |
| C050414 | tripterine | tripterine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] | 24111524 |
| C080163 | trovafloxacin | "[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTEN mRNA" | 18930950 |
| C113580 | U 0126 | U 0126 inhibits the reaction [sodium arsenite results in decreased expression of PTEN protein] | 26432159 |
| D014520 | Urethane | Urethane results in increased expression of PTEN mRNA | 28818685 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTEN mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid results in decreased expression of PTEN mRNA | 28001369 |
| D014635 | Valproic Acid | Valproic Acid results in decreased methylation of PTEN gene | 29154799 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of PTEN mRNA | 26272509 |
| D014638 | Vanadates | Vanadates results in increased phosphorylation of PTEN protein | 19377290 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased methylation of PTEN gene | 25560391 |
| C521013 | veliparib | PTEN protein results in decreased susceptibility to veliparib | 20530668 |
| D020888 | Vigabatrin | [Pentylenetetrazole co-treated with Vigabatrin] affects the expression of PTEN mRNA | 21503142 |
| C025643 | vinclozolin | vinclozolin results in increased expression of PTEN mRNA | 15686871 |
| C017963 | vinyl carbamate | vinyl carbamate results in decreased expression of PTEN mRNA | 17849452 |
| D002762 | Cholecalciferol | Cholecalciferol promotes the reaction [Cladribine results in increased expression of PTEN mRNA] | 21801466 |
| D002762 | Cholecalciferol | Cholecalciferol promotes the reaction [Cladribine results in increased methylation of PTEN promoter] | 21801466 |
| D002762 | Cholecalciferol | Cholecalciferol results in decreased methylation of PTEN promoter | 21801466 |
| D002762 | Cholecalciferol | Cholecalciferol results in increased expression of PTEN mRNA | 21801466 |
| D002762 | Cholecalciferol | Cladribine promotes the reaction [Cholecalciferol results in decreased methylation of PTEN promoter] | 21801466 |
| D002762 | Cholecalciferol | Cladribine promotes the reaction [Cholecalciferol results in increased expression of PTEN mRNA] | 21801466 |
| D002762 | Cholecalciferol | Cholecalciferol results in increased expression of PTEN mRNA | 16508948 |
| C111237 | vorinostat | vorinostat results in decreased expression of PTEN mRNA | 27188386 |
| D014873 | Water Pollutants | Water Pollutants results in decreased expression of PTEN mRNA | 23591932 |
| D014874 | Water Pollutants, Chemical | "Water Pollutants, Chemical affects the expression of PTEN mRNA" | 25208076 |
| C009687 | wortmannin | wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Doxorubicin] | 17935137 |
| C009687 | wortmannin | wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Etoposide] | 17935137 |
| C009687 | wortmannin | wortmannin inhibits the reaction [nonylphenol results in decreased expression of PTEN protein] | 27832966 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein]] | 20100827 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Zinc Sulfate results in decreased expression of PTEN protein] | 20100827 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Zinc Sulfate results in increased ubiquitination of PTEN protein] | 20100827 |
| D015032 | Zinc | Zinc promotes the reaction [PTEN protein binds to MTF1 protein] | 21883094 |
| D015032 | Zinc | PTEN protein inhibits the reaction [Zinc results in increased expression of PTGS2 mRNA] | 15980035 |
| D015032 | Zinc | PTEN protein inhibits the reaction [Zinc results in increased phosphorylation of AKT1 protein] | 15980035 |
| D015032 | Zinc | Zinc results in increased degradation of PTEN protein | 15980035 |
| D019287 | Zinc Sulfate | PTEN mutant form inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA] | 21883094 |
| D019287 | Zinc Sulfate | PTEN promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA] | 21883094 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in decreased expression of PTEN protein | 20100827 |
| D019287 | Zinc Sulfate | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc Sulfate results in decreased stability of PTEN protein] | 20100827 |
| D019287 | Zinc Sulfate | PTEN protein results in increased susceptibility to Zinc Sulfate | 20100827 |
| D019287 | Zinc Sulfate | wortmannin inhibits the reaction [Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein]] | 20100827 |
| D019287 | Zinc Sulfate | wortmannin inhibits the reaction [Zinc Sulfate results in decreased expression of PTEN protein] | 20100827 |
| D019287 | Zinc Sulfate | wortmannin inhibits the reaction [Zinc Sulfate results in increased ubiquitination of PTEN protein] | 20100827 |
| D019287 | Zinc Sulfate | Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein] | 20100827 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in decreased expression of and results in decreased stability of PTEN protein | 20100827 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in increased ubiquitination of PTEN protein | 20100827 |
| D019287 | Zinc Sulfate | PTEN mutant form inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA] | 21883094 |
| D019287 | Zinc Sulfate | PTEN mutant form inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA] | 21883094 |
| D019287 | Zinc Sulfate | Zinc Sulfate promotes the reaction [PTEN protein binds to MTF1 protein] | 21883094 |