Gene: RNF150

57484
-
ring finger protein 150
protein-coding
4q31.21
Ensembl:ENSG00000170153 Vega:OTTHUMG00000161380 UniprotKB:Q9ULK6
NC_000004.12
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.016e-1 (AD)  3.353e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZDHHC230.906
KCNA40.894
SGIP10.893
PTPRO0.893
SHISA90.89
DGKI0.889
LRRTM30.889
NBEA0.886
ANO30.886
TENM30.886

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CSAG1-0.527
MYL3-0.509
FLT3LG-0.496
COPZ2-0.495
ROM1-0.487
RAB13-0.486
HEY2-0.485
SNHG18-0.462
PSTPIP1-0.446
C1QTNF5-0.444

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C496492abrineabrine results in increased expression of RNF150 mRNA22595364
C015001arsenitearsenite results in increased methylation of RNF150 promoter23974009
C487081belinostatbelinostat results in increased expression of RNF150 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
D004958Estradiol[Estradiol co-treated with Progesterone] results in increased expression of RNF150 mRNA20660070
C044887beta-methylcholinebeta-methylcholine affects the expression of RNF150 mRNA21179406
C006780bisphenol Abisphenol A results in decreased expression of RNF150 mRNA27685785
C006780bisphenol A[bisphenol A co-treated with Genistein] results in decreased methylation of RNF150 gene28505145
C006780bisphenol Abisphenol A results in increased expression of RNF150 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of RNF150 gene28505145
D002220CarbamazepineCarbamazepine affects the expression of RNF150 mRNA25979313
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of RNF150 mRNA23914054
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of RNF150 mRNA28628672
D002945CisplatinCisplatin results in increased expression of RNF150 mRNA27392435
D019422Dietary SucroseDietary Sucrose results in increased expression of RNF150 mRNA26033743
C118739entinostatentinostat results in decreased expression of RNF150 mRNA27188386
C118739entinostatentinostat results in increased expression of RNF150 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C082360fipronilfipronil results in decreased expression of RNF150 mRNA23962444
D019833Genistein[bisphenol A co-treated with Genistein] results in decreased methylation of RNF150 gene28505145
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of RNF150 mRNA21179406
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of RNF150 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of RNF150 mRNA28628672
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of RNF150 mRNA26644586
C045463leflunomideleflunomide results in increased expression of RNF150 mRNA28988120
C005095malachite greenRNF150 gene SNP affects the susceptibility to malachite green25622337
D008727MethotrexateMethotrexate affects the expression of RNF150 mRNA18502557
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of RNF150 mRNA28001369
D009532NickelNickel results in decreased expression of RNF150 mRNA24768652|2558310
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of RNF150 mRNA26272509
D052638Particulate MatterParticulate Matter results in decreased expression of RNF150 mRNA23085030
D011374Progesterone[Estradiol co-treated with Progesterone] results in increased expression of RNF150 mRNA20660070
D011374ProgesteroneProgesterone results in increased expression of RNF150 mRNA22238285
C005556propionaldehydepropionaldehyde results in increased expression of RNF150 mRNA26079696
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of RNF150 mRNA25895662
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of RNF150 mRNA23806026
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RNF150 mRNA24680724
D014212TretinoinTretinoin results in increased expression of RNF150 mRNA21934132
C012589trichostatin Atrichostatin A results in increased expression of RNF150 mRNA24935251
D014520UrethaneUrethane results in increased expression of RNF150 mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of RNF150 mRNA23179753|2493525
D001335Vehicle EmissionsVehicle Emissions affects the methylation of RNF150 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0046872metal ion binding-IEA-  
GO:0061630ubiquitin protein ligase activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25609945EGLN2 and RNF150 genetic variants are associated with chronic obstructive pulmonary disease risk in the Chinese population. (2015)Ding YInt J Chron Obstruct Pulmon Dis