Gene: AHRR

57491
AHH|AHHR|bHLHe77
aryl-hydrocarbon receptor repressor
protein-coding
5p15.33
Ensembl:ENSG00000063438 MIM:606517 Vega:OTTHUMG00000162171 UniprotKB:A9YTQ3
NG_029834.1
PubMed
ND
52   
2.346e-1 (AD)  6.332e-1 (ND)   (Frontal_Cortex)
6.447e-1 (AD)  1.362e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg18205372chr5:386883AHRRGene body1.568e-4Alcohol use disorders26763658
cg14817490chr5:392920AHRR2.710e-8Smoking22232023
cg05575921chr5:373378AHRR1.500e-107Maternal smoking in pregnancy27040690
cg23067299chr5:323907AHRR4.680e-41Maternal smoking in pregnancy27040690
cg21161138chr5:399360AHRR1.460e-41Maternal smoking in pregnancy27040690
cg08606254chr5:323969AHRR1.680e-36Maternal smoking in pregnancy27040690
cg11902777chr5:368843AHRR9.150e-31Maternal smoking in pregnancy27040690
cg03991871chr5:368447AHRR1.130e-18Maternal smoking in pregnancy27040690
cg23916896chr5:368804AHRR3.530e-22Maternal smoking in pregnancy27040690
cg17924476chr5:323794AHRR9.710e-15Maternal smoking in pregnancy27040690
cg12806681chr5:368394AHRR9.180e-16Maternal smoking in pregnancy27040690
cg01970407chr5:323320AHRR6.320e-11Maternal smoking in pregnancy27040690
cg26703534chr5:377358AHRR2.890e-11Maternal smoking in pregnancy27040690
cg14817490chr5:392920AHRR1.280e-11Maternal smoking in pregnancy27040690
cg26954197chr5:436816AHRR2.100e-9Maternal smoking in pregnancy27040690
cg07448928chr5:427755AHRR5.710e-9Maternal smoking in pregnancy27040690
cg01899089chr5:369969AHRR4.630e-8Maternal smoking in pregnancy27040690
cg10841124chr5:433274AHRR9.440e-8Maternal smoking in pregnancy27040690
cg05575921chr5:373378AHRR1.640e-193Maternal smoking in pregnancy27040690
cg23067299chr5:323907AHRR9.930e-57Maternal smoking in pregnancy27040690
cg21161138chr5:399360AHRR1.780e-54Maternal smoking in pregnancy27040690
cg08606254chr5:323969AHRR1.850e-49Maternal smoking in pregnancy27040690
cg11902777chr5:368843AHRR6.090e-43Maternal smoking in pregnancy27040690
cg03991871chr5:368447AHRR3.630e-27Maternal smoking in pregnancy27040690
cg23916896chr5:368804AHRR1.000e-24Maternal smoking in pregnancy27040690
cg17924476chr5:323794AHRR8.800e-23Maternal smoking in pregnancy27040690
cg12806681chr5:368394AHRR4.440e-20Maternal smoking in pregnancy27040690
cg01970407chr5:323320AHRR6.800e-20Maternal smoking in pregnancy27040690
cg26703534chr5:377358AHRR2.140e-17Maternal smoking in pregnancy27040690
cg14817490chr5:392920AHRR3.130e-14Maternal smoking in pregnancy27040690
cg17401179chr5:400517AHRR1.290e-11Maternal smoking in pregnancy27040690
cg26954197chr5:436816AHRR5.080e-10Maternal smoking in pregnancy27040690
cg07448928chr5:427755AHRR1.370e-9Maternal smoking in pregnancy27040690
cg01899089chr5:369969AHRR5.470e-9Maternal smoking in pregnancy27040690
cg10841124chr5:433274AHRR7.110e-9Maternal smoking in pregnancy27040690
cg22698028chr5:400494AHRR7.390e-9Maternal smoking in pregnancy27040690
cg16172278chr5:428101AHRR1.950e-8Maternal smoking in pregnancy27040690
cg24688690chr5:345850AHRR3.360e-8Maternal smoking in pregnancy27040690
cg11554391chr5:321320AHRR7.270e-8Maternal smoking in pregnancy27040690
cg05575921chr5:373378AHRR1.350e-206Maternal smoking in pregnancy27040690
cg23067299chr5:323907AHRR6.360e-63Maternal smoking in pregnancy27040690
cg21161138chr5:399360AHRR6.610e-59Maternal smoking in pregnancy27040690
cg08606254chr5:323969AHRR5.270e-46Maternal smoking in pregnancy27040690
cg11902777chr5:368843AHRR1.020e-36Maternal smoking in pregnancy27040690
cg03991871chr5:368447AHRR1.190e-27Maternal smoking in pregnancy27040690
cg23916896chr5:368804AHRR4.310e-26Maternal smoking in pregnancy27040690
cg17924476chr5:323794AHRR2.240e-25Maternal smoking in pregnancy27040690
cg12806681chr5:368394AHRR4.660e-20Maternal smoking in pregnancy27040690
cg01970407chr5:323320AHRR3.810e-21Maternal smoking in pregnancy27040690
cg26703534chr5:377358AHRR4.820e-19Maternal smoking in pregnancy27040690
cg14817490chr5:392920AHRR3.020e-27Maternal smoking in pregnancy27040690
cg17401179chr5:400517AHRR2.130e-15Maternal smoking in pregnancy27040690
cg26954197chr5:436816AHRR1.360e-10Maternal smoking in pregnancy27040690
cg07448928chr5:427755AHRR3.210e-9Maternal smoking in pregnancy27040690
cg01899089chr5:369969AHRR8.580e-12Maternal smoking in pregnancy27040690
cg10841124chr5:433274AHRR8.470e-9Maternal smoking in pregnancy27040690
cg22698028chr5:400494AHRR1.650e-10Maternal smoking in pregnancy27040690
cg11554391chr5:321320AHRR2.750e-8Maternal smoking in pregnancy27040690
cg12202185chr5:369088AHRR1.710e-8Maternal smoking in pregnancy27040690
cg04551776chr5:393366AHRR9.790e-8Maternal smoking in pregnancy27040690
cg05575921chr5:373378AHRR1.870e-9Maternal smoking in pregnancy27040690
cg11902777chr5:368843AHRR2.620e-10Maternal smoking in pregnancy27040690
cg01097768chr5:378854AHRR6.800e-35Smoking27651444
cg04551776chr5:393366AHRR5.800e-31Smoking27651444
cg11902777chr5:368843AHRR9.100e-30Smoking27651444
cg23576855chr5:373299AHRR7.100e-27Smoking27651444
cg05575921chr5:373378AHRR4.500e-26Smoking27651444
cg00300637chr5:319433AHRR3.800e-22Smoking27651444
cg26703534chr5:377358AHRR1.200e-21Smoking27651444
cg23916896chr5:368804AHRR6.300e-20Smoking27651444
cg14817490chr5:392920AHRR1.200e-19Smoking27651444
cg11554391chr5:321320AHRR9.800e-19Smoking27651444
cg12806681chr5:368394AHRR2.600e-18Smoking27651444
cg26954197chr5:436816AHRR5.600e-18Smoking27651444
cg17924476chr5:323794AHRR9.300e-18Smoking27651444
cg17287155chr5:393347AHRR5.400e-17Smoking27651444
cg23067299chr5:323907AHRR1.500e-16Smoking27651444
cg03991871chr5:368447AHRR2.600e-16Smoking27651444
cg21161138chr5:399360AHRR4.400e-16Smoking27651444
cg01899089chr5:369969AHRR1.100e-15Smoking27651444
cg08606254chr5:323969AHRR4.700e-15Smoking27651444
cg25648203chr5:395444AHRR2.100e-14Smoking27651444
cg10841124chr5:433274AHRR3.800e-14Smoking27651444
cg03604011chr5:400201AHRR4.700e-12Smoking27651444
cg24090911chr5:400732AHRR8.700e-12Smoking27651444
cg26850624chr5:429559AHRR8.900e-12Smoking27651444
cg09338136chr5:344057AHRR1.600e-11Smoking27651444
cg24688690chr5:345850AHRR1.600e-11Smoking27651444
cg22356527chr5:374425AHRR2.900e-11Smoking27651444
cg09084391chr5:346247AHRR1.000e-9Smoking27651444
cg16219322chr5:399012AHRR2.300e-9Smoking27651444
cg14647125chr5:403112AHRR4.800e-9Smoking27651444
cg26076054chr5:421317AHRR1.200e-8Smoking27651444
cg08858540chr5:346238AHRR1.300e-8Smoking27651444
cg25004427chr5:326523AHRR1.600e-8Smoking27651444
cg16336872chr5:435267AHRR6.800e-8Smoking27651444
cg26529655chr5:424371AHRR8.700e-8Smoking27651444
cg16896326chr5:322134AHRR9.400e-8Smoking27651444
cg03991871chr5:368447AHRR5.510e-8Alcohol consumption per day27843151
cg25648203chr5:395444AHRR5.270e-8Alcohol consumption per day27843151
cg05575921chr5:373378AHRR8.100e-87Tobacco smoking28225026
cg26703534chr5:377358AHRR1.640e-37Tobacco smoking28225026
cg25648203chr5:395444AHRR9.410e-33Tobacco smoking28225026
cg14817490chr5:392920AHRR4.700e-25Tobacco smoking28225026
cg23576855chr5:373299AHRR4.280e-21Tobacco smoking28225026
cg11902777chr5:368843AHRR2.030e-19Tobacco smoking28225026
cg23916896chr5:368804AHRR2.110e-17Tobacco smoking28225026
cg04551776chr5:393366AHRR1.000e-15Tobacco smoking28225026
cg17287155chr5:393347AHRR1.910e-14Tobacco smoking28225026
cg03991871chr5:368447AHRR5.860e-14Tobacco smoking28225026
cg12806681chr5:368394AHRR2.000e-13Tobacco smoking28225026
cg11554391chr5:321320AHRR1.620e-11Tobacco smoking28225026
cg24090911chr5:400732AHRR1.480e-10Tobacco smoking28225026
cg01899089chr5:369969AHRR1.590e-9Tobacco smoking28225026
cg03604011chr5:400201AHRR9.290e-9Tobacco smoking28225026
cg16219322chr5:399012AHRR4.700e-8Tobacco smoking28225026
cg05575921chr5:373378AHRR1.580e-160Smoking28686328
cg21161138chr5:399360AHRR4.200e-75Smoking28686328
cg25648203chr5:395444AHRR6.780e-60Smoking28686328
cg26703534chr5:377358AHRR3.800e-56Smoking28686328
cg12806681chr5:368394AHRR1.180e-36Smoking28686328
cg14817490chr5:392920AHRR9.450e-36Smoking28686328
cg03991871chr5:368447AHRR8.640e-35Smoking28686328
cg23576855chr5:373299AHRR1.850e-32Smoking28686328
cg23916896chr5:368804AHRR1.360e-21Smoking28686328
cg24090911chr5:400732AHRR2.440e-21Smoking28686328
cg01899089chr5:369969AHRR1.060e-17Smoking28686328
cg04551776chr5:393366AHRR1.630e-16Smoking28686328
cg11902777chr5:368843AHRR4.520e-14Smoking28686328
cg17287155chr5:393347AHRR5.010e-12Smoking28686328
cg11554391chr5:321320AHRR5.640e-12Smoking28686328
cg25004427chr5:326523AHRR5.860e-11Smoking28686328
cg03604011chr5:400201AHRR5.180e-9Smoking28686328
cg17924476chr5:323794AHRR8.140e-9Smoking28686328
cg16219322chr5:399012AHRR1.760e-8Smoking28686328

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CACNA1G0.767
CACNA1C0.747
CACNA1D0.747
CELSR30.741
PDE4C0.739
CACNA1B0.731
RIMBP20.73
KIAA07530.728
R3HDM10.727
VWA70.726

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MBNL3-0.466
CTNNA3-0.439
HEY2-0.438
SNHG18-0.425
COPZ2-0.424
MYOT-0.41
REST-0.408
SH2D1A-0.401
FAM107B-0.399
BCAS1-0.398

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0468391,2,3,4,6,7,8-heptachlorodibenzodioxin"1,2,3,4,6,7,8-heptachlorodibenzodioxin results in increased expression of AHRR mRNA"25654323
C4736501,2,3,4,6,7,8-heptachlorodibenzofuran"1,2,3,4,6,7,8-heptachlorodibenzofuran analog results in increased expression of AHRR mRNA"25654323
C4736501,2,3,4,6,7,8-heptachlorodibenzofuran"1,2,3,4,6,7,8-heptachlorodibenzofuran results in increased expression of AHRR mRNA"25654323
C0514121,2,3,4,7,8-hexachlorodibenzofuran"1,2,3,4,7,8-hexachlorodibenzofuran analog results in increased expression of AHRR mRNA"25654323
C0514121,2,3,4,7,8-hexachlorodibenzofuran"1,2,3,4,7,8-hexachlorodibenzofuran results in increased expression of AHRR mRNA"25654323
C0514521,2,3,7,8-pentachlorodibenzo-p-dioxin"1,2,3,7,8-pentachlorodibenzo-p-dioxin results in increased expression of AHRR mRNA"24472611|2565432
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of AHRR mRNA"26377693
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of AHRR mRNA19933214
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of AHRR mRNA"27291303
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of AHRR mRNA"24472611|2565432
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased expression of AHRR mRNA"25654323
C0140242,4,5,2',4',5'-hexachlorobiphenyl"AHRR polymorphism affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl"25084496
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"AHRR protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"23208499
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased expression of AHRR mRNA25203682
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl results in increased expression of AHRR mRNA"16519320
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl results in increased expression of AHRR mRNA"17291011
C0284513,4,3',4'-tetrachlorobiphenyl"4-nonylphenol inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of AHRR mRNA]"17291011
C0284513,4,3',4'-tetrachlorobiphenyl"alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of AHRR mRNA]"17291011
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHRR mRNA"21703328|2314675
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHRR mRNA"23196670
C0415944-nonylphenol[4-nonylphenol co-treated with fulvestrant] results in increased expression of AHRR mRNA17291011
C0415944-nonylphenol"4-nonylphenol inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of AHRR mRNA]"17291011
C1118556-formylindolo(3,2-b)carbazole"6-formylindolo(3,2-b)carbazole results in increased expression of AHRR mRNA"27783115
C1118556-formylindolo(3,2-b)carbazole"CL 075 promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of AHRR mRNA]"27783115
C1118556-formylindolo(3,2-b)carbazole"6-formylindolo(3,2-b)carbazole results in increased expression of AHRR mRNA"25203682
D020106AcrylamideAcrylamide results in decreased expression of AHRR mRNA28959563
C016601afimoxifeneafimoxifene results in increased expression of AHRR mRNA19901195
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of AHRR gene27153756
D000393Air PollutantsAir Pollutants results in increased expression of AHRR mRNA18367723
C011512alpha-naphthoflavone"alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of AHRR mRNA]"17291011
C508838annomontineannomontine results in increased expression of AHRR mRNA20449727
C034020anthracene[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHRR protein28710019
D001115ArecolineArecoline inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]17234337
D001151ArsenicArsenic affects the methylation of AHRR gene25304211
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of AHRR mRNA26377693
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of AHRR mRNA27858113
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of AHRR mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of AHRR mRNA26377693
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of AHRR mRNA14551997
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of AHRR mRNA25218365
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of AHRR mRNA12520768
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AHRR mRNA18164116
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of AHRR mRNA26377693
D001564Benzo(a)pyreneAHRR inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]21256203
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of AHRR mRNA21714911
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of AHRR mRNA21256954
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of AHRR22581694
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of AHRR mRNA19879285|2006483
D001564Benzo(a)pyreneQuercetin inhibits the reaction [Benzo(a)pyrene results in decreased expression of AHRR mRNA]21256954
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of AHRR mRNA16519320
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of AHRR mRNA20127859
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of AHRR mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of AHRR mRNA21569818|2327456
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of AHRR mRNA26466350
D001564Benzo(a)pyreneSulpiride promotes the reaction [Benzo(a)pyrene results in increased expression of AHRR mRNA]26466350
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of AHRR mRNA"19150397
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of AHRR mRNA"20382639
D004958EstradiolAHRR protein inhibits the reaction [[Estradiol results in increased activity of ESR1 protein] which results in increased expression of CYP1A1 mRNA]21047992
D004958EstradiolAHRR protein inhibits the reaction [[[Tetrachlorodibenzodioxin results in increased activity of AHR protein] co-treated with [Estradiol results in increased activity of ESR1 protein]] results in increased expression of CYP1A1 mRNA]21047992
D004958EstradiolEstradiol affects the expression of AHRR mRNA24777823
D004958Estradiol[Progesterone co-treated with Estradiol] affects the expression of AHRR mRNA24777823
C006780bisphenol Abisphenol A results in increased expression of AHRR mRNA16284450
C006780bisphenol Abisphenol A affects the expression of AHRR mRNA25181051
D002220CarbamazepineCarbamazepine affects the expression of AHRR mRNA25979313
D002243CarbolinesCarbolines analog results in increased expression of AHRR mRNA20449727
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of AHRR mRNA25795401
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AHRR gene20938992
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of AHRR mRNA27858113
C551788CL 075"CL 075 promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of AHRR mRNA]"27783115
C551788CL 075CL 075 promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]27783115
C551788CL 075CL 075 results in increased expression of AHRR mRNA27783115
D003033Coal TarCoal Tar results in decreased expression of AHRR mRNA27858113
D003033Coal Tar[Vehicle Emissions analog co-treated with Coal Tar analog co-treated with Tobacco Smoke Pollution analog] results in increased expression of AHRR mRNA23274566
D003033Coal Tar[Vehicle Emissions analog co-treated with Coal Tar analog] results in increased expression of AHRR mRNA23274566
C018021cobaltous chloridecobaltous chloride results in decreased expression of AHRR mRNA19320972
D003367CotinineCotinine affects the methylation of AHRR gene22851337
D016572CyclosporineCyclosporine results in decreased methylation of AHRR promoter27989131
C014347decitabinedecitabine results in increased expression of AHRR mRNA21515334
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of AHRR mRNA"23274566
C023614dibenzofurandibenzofuran analog results in increased expression of AHRR mRNA20566336
D003994BucladesineBucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]21979172
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of AHRR mRNA27392435
D002945CisplatinCisplatin results in decreased expression of AHRR mRNA27392435
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of AHRR mRNA26924002
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AHRR mRNA18164116
D0151279,10-Dimethyl-1,2-benzanthracene"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of AHRR mRNA"27891153
C024629dimethyl phthalatedimethyl phthalate results in decreased expression of AHRR mRNA26924002
D004147DioxinsAHRR gene polymorphism results in increased susceptibility to Dioxins15474075|1575856
D004147DioxinsAHRR protein polymorphism results in increased susceptibility to Dioxins11835227
D004237DiuronDiuron results in decreased expression of AHRR mRNA25152437
D004237DiuronDiuron results in increased expression of AHRR mRNA21551480
D004967EstrogensEstrogens inhibits the reaction [AHRR protein results in increased expression of CYP1A1 mRNA]15597882
D004967EstrogensEstrogens results in increased activity of AHRR protein15597882
D005054EugenolEugenol results in increased expression of AHRR mRNA22686307
C000499ferric oxideferric oxide analog results in increased expression of AHRR mRNA24525745
C007738fluoranthene[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHRR protein28710019
C007738fluoranthenefluoranthene results in increased expression of AHRR mRNA25268939
C007738fluorantheneTNF protein inhibits the reaction [fluoranthene results in increased expression of AHRR mRNA]25268939
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AHRR gene20938992
D004397FonofosFonofos results in increased methylation of AHRR promoter22847954
C070081fulvestrant[4-nonylphenol co-treated with fulvestrant] results in increased expression of AHRR mRNA17291011
C039281furanfuran results in increased methylation of AHRR gene22079235
D017313FenretinideFenretinide results in increased expression of AHRR mRNA16467112
C036643isoeugenolisoeugenol results in increased expression of AHRR mRNA22686307
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of AHRR mRNA27392435
C072105KN 93KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]18089838
C476223laquinimodlaquinimod analog results in increased expression of AHRR mRNA28433708
D008558MelphalanMelphalan results in decreased expression of AHRR mRNA22363485
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AHRR gene20938992
D008748MethylcholanthreneMethylcholanthrene results in increased expression of AHRR mRNA12655030|1467275
D008748MethylcholanthreneMethylcholanthrene results in increased expression of AHRR mRNA11423533|9887096
D008748Methylcholanthrene[Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA11423533
C517284monomethyl phthalatemonomethyl phthalate affects the expression of AHRR mRNA26924002
C560625N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amineN-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]21493753
C058346N-(4-methoxyphenyl)retinamideN-(4-methoxyphenyl)retinamide results in increased expression of AHRR mRNA16467112
C031721naphthalene[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHRR protein28710019
D010069Oxadiazoles[Oxadiazoles analog co-treated with FGF2 protein] results in increased expression of AHRR mRNA23212921
D010100OxygenOxygen deficiency results in decreased expression of AHRR mRNA17599377
D010278ParathionParathion results in increased methylation of AHRR promoter22847954
D052638Particulate MatterParticulate Matter results in increased expression of AHRR mRNA22178795
D052638Particulate MatterParticulate Matter results in increased expression of AHRR mRNA24365139
C031181phenanthrene[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHRR protein28710019
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls results in increased expression of AHRR mRNA11742002
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons affects the expression of AHRR protein28710019
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in decreased expression of AHRR mRNA28710019
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased expression of AHRR mRNA12655030
D011374ProgesteroneProgesterone affects the expression of AHRR mRNA24777823
D011374Progesterone[Progesterone co-treated with Estradiol] affects the expression of AHRR mRNA24777823
C005556propionaldehydepropionaldehyde results in increased expression of AHRR mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of AHRR mRNA24780913
C043680ptaquiloside[ptaquiloside co-treated with Sodium Selenite] results in increased expression of AHRR mRNA23274088
C043680ptaquilosideptaquiloside results in increased expression of AHRR mRNA23274088
C030984pyrene[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHRR protein28710019
D011794QuercetinQuercetin inhibits the reaction [Benzo(a)pyrene results in decreased expression of AHRR mRNA]21256954
D011794QuercetinQuercetin results in decreased expression of AHRR mRNA21256954
D011794QuercetinQuercetin results in increased expression of AHRR mRNA21256954|2163298
C059514resveratrolresveratrol results in increased expression of AHRR protein24136580
C028632rutecarpinerutecarpine results in increased expression of AHRR mRNA20449727
C116890SemaxinibAHRR protein affects the reaction [Semaxinib results in increased expression of CDKN1A mRNA]28424418
C116890SemaxinibSemaxinib results in increased expression of AHRR mRNA28424418
D012906SmokeSmoke results in increased expression of AHRR mRNA21095227
D018038Sodium Selenite[ptaquiloside co-treated with Sodium Selenite] results in increased expression of AHRR mRNA23274088
D018038Sodium SeleniteSodium Selenite results in increased expression of AHRR mRNA23274088
C552240StemRegenin 1StemRegenin 1 results in decreased expression of AHRR mRNA20688981
D013469SulpirideSulpiride promotes the reaction [Benzo(a)pyrene results in increased expression of AHRR mRNA]26466350
C516109tasquinimodtasquinimod analog results in increased expression of AHRR mRNA28433708
C012568terbufosterbufos results in increased methylation of AHRR promoter22847954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA20055451
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR1 protein]11742002
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR2 protein]11742002
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA11742002
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]21047992
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [[[Tetrachlorodibenzodioxin results in increased activity of AHR protein] co-treated with [Estradiol results in increased activity of ESR1 protein]] results in increased expression of CYP1A1 mRNA]21047992
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]21047992
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]21047992
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA21047992
D013749TetrachlorodibenzodioxinAHRR inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]21256203
D013749TetrachlorodibenzodioxinArecoline inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]17234337
D013749TetrachlorodibenzodioxinCL 075 promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]27783115
D013749TetrachlorodibenzodioxinKN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]18089838
D013749TetrachlorodibenzodioxinN-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]21493753
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to CYP1A1 gene]24806346
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to CYP1B1 gene]24806346
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to MAP2K7 gene]28681081
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to PNPO gene]28681081
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to RPL22 gene]28681081
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to XRCC6 gene]28681081
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA12655030|1642657
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR protein24806346
D013749TetrachlorodibenzodioxinTIPARP mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]24806346
D013749TetrachlorodibenzodioxinAHRR gene mutant form promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 gene]]24806346
D013749TetrachlorodibenzodioxinAHRR gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]24806346
D013749TetrachlorodibenzodioxinAHRR gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]24806346
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of GPT protein]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL14 mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL2 mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL3 mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL5 mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B protein]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of IL6 mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]26862745
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]18385208
D013749TetrachlorodibenzodioxinARNT affects the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]20935161
D013749TetrachlorodibenzodioxinBucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]21979172
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of AHRR mRNA21570461|2570343
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of AHRR mRNA16214954
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of AHRR mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [AHRR gene mutant form results in increased expression of AHR mRNA]24806346
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to AHRR gene]20819909
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA12520768|1457564
D013749Tetrachlorodibenzodioxintributyltin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]22749964
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA28077779
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA15013435|1566442
D013749TetrachlorodibenzodioxinAHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]23859880|2759092
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to BRCA1 promoter]24136580
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR24136580
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA17069994|1899072
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR1A mRNA]18385208
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR1B mRNA]18385208
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AHRR mRNA18385208
D013749TetrachlorodibenzodioxinAHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]28681081
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA11423533
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of AHRR mRNA11423533
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the methylation of AHRR gene26756918
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased methylation of AHRR gene26864933
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of AHRR mRNA27404394|2786577
D014028Tobacco Smoke PollutionNFE2L2 protein inhibits the reaction [Tobacco Smoke Pollution affects the expression of AHRR mRNA]20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of AHRR mRNA20133372
D014028Tobacco Smoke Pollution[Vehicle Emissions analog co-treated with Coal Tar analog co-treated with Tobacco Smoke Pollution analog] results in increased expression of AHRR mRNA23274566
C032910triadimefontriadimefon affects the expression of AHRR mRNA20659493
C011559tributyltintributyltin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA]22749964
C011559tributyltintributyltin results in decreased expression of AHRR mRNA22749964
D001335Vehicle Emissions[Vehicle Emissions analog co-treated with Coal Tar analog co-treated with Tobacco Smoke Pollution analog] results in increased expression of AHRR mRNA23274566
D001335Vehicle Emissions[Vehicle Emissions analog co-treated with Coal Tar analog] results in increased expression of AHRR mRNA23274566
D001335Vehicle EmissionsVehicle Emissions analog results in increased expression of AHRR mRNA23274566
D001335Vehicle EmissionsVehicle Emissions results in increased expression of AHRR mRNA24365139

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0001191transcriptional repressor activity, RNA polymerase II transcription factor binding-IBA21873635  
GO:0003677DNA binding-IEA-  
GO:0005515protein binding-IPI28904176  
GO:0046983protein dimerization activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IBA21873635  
GO:0000122negative regulation of transcription by RNA polymerase II-IEA-  
GO:0006351transcription, DNA-templated-IEA-  
GO:0006805xenobiotic metabolic process-TAS-  
GO:0009410response to xenobiotic stimulus-IBA21873635  
GO:0045944positive regulation of transcription by RNA polymerase II-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005829cytosol-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-1989781PPARA activates gene expressionTAS
R-HSA-211859Biological oxidationsTAS
R-HSA-211945Phase I - Functionalization of compoundsTAS
R-HSA-400206Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)TAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-8937144Aryl hydrocarbon receptor signallingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26043106Novel epigenetic changes unveiled by monozygotic twins discordant for smoking habits. (2015)Allione APLoS One
22851337450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. (2012 Oct)Joubert BREnviron Health Perspect
28820654Locus-specific DNA methylation in the placenta is associated with levels of pro-inflammatory proteins in cord blood and they are both independently affected by maternal smoking during pregnancy. (2017)van Otterdijk SDEpigenetics
25424692Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation. (2014 Oct)Tsaprouni LGEpigenetics
29055820IgG glycosylation and DNA methylation are interconnected with smoking. (2018 Mar)Wahl ABiochim Biophys Acta
27613907Secondhand Tobacco Smoke Exposure Associations With DNA Methylation of the Aryl Hydrocarbon Receptor Repressor. (2017 Apr 1)Reynolds LMNicotine Tob Res
28453567Performance of urine cotinine and hypomethylation of AHRR and F2RL3 as biomarkers for smoking exposure in a population-based cohort. (2017)Lee DHPLoS One
27924164Smoking-associated DNA methylation markers predict lung cancer incidence. (2016)Zhang YClin Epigenetics
26252179Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight. (2015)Burris HHEpigenetics
28454697Tissue differences in DNA methylation changes at AHRR in full term low birth weight in maternal blood, placenta and cord blood in Chinese. (2017 Apr)Tian FYPlacenta
29262847Systems-epigenomics inference of transcription factor activity implicates aryl-hydrocarbon-receptor inactivation as a key event in lung cancer development. (2017 Dec 20)Chen YGenome Biol
25325234Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an independent cohort at birth through 17 years of age. (2015 Feb)Lee KWEnviron Health Perspect
29722794DNA-methylation of the cancer-related genes F2RL3 and AHRR is associated with occupational exposure to polycyclic aromatic hydrocarbons. (2018 May 2)Alhamdow ACarcinogenesis
25218365Diversified expression of aryl hydrocarbon receptor dependent genes in human laryngeal squamous cell carcinoma cell lines treated with beta-naphthoflavone. (2014 Nov 18)Brauze DToxicol Lett
28085253Crowd-Sourced Verification of Computational Methods and Data in Systems Toxicology: A Case Study with a Heat-Not-Burn Candidate Modified Risk Tobacco Product. (2017 Apr 17)Poussin CChem Res Toxicol
28816414Accuracy and utility of an epigenetic biomarker for smoking in populations with varying rates of false self-report. (2017 Sep)Andersen AMAm J Med Genet B Neuropsychiatr Genet
26307030DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical Atherosclerosis. (2015 Oct)Reynolds LMCirc Cardiovasc Genet
27208563Epigenetic regulation of neurodevelopmental genes in response to in utero exposure to phthalate plastic chemicals: How can we delineate causal effects? (2016 Jul)Ponsonby ALNeurotoxicology
28100713AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality. (2017 Jul)Bojesen SEThorax
25371448Temporal stability and determinants of white blood cell DNA methylation in the breakthrough generations study. (2015 Jan)Flanagan JMCancer Epidemiol Biomarkers Prev
26441693Ethnicity and Smoking-Associated DNA Methylation Changes at HIV Co-Receptor GPR15. (2015)Dogan MVFront Psychiatry
29412867Urinary 1-hydroxypyrene and smoking are determinants of LINE-1 and AhRR promoter methylation in coke oven workers. (2018 Feb)Yang JMutat Res
28494218Maternal cigarette smoking during pregnancy and offspring DNA methylation in midlife. (2018)Tehranifar PEpigenetics
24120260Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking. (2013 Oct 11)Philibert RAClin Epigenetics
28854564Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers. (2017 Aug 1)Stueve TRHum Mol Genet
29325019Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation. (2018 Mar 15)Zaghlool SBHum Mol Genet
27403598Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates. (2016 Sep)Gonseth SEpigenetics
24559495The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women. (2014 Feb 22)Dogan MVBMC Genomics
25552657Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC). (2015 Apr 15)Richmond RCHum Mol Genet
25480659DNA methylation alterations in response to prenatal exposure of maternal cigarette smoking: A persistent epigenetic impact on health from maternal lifestyle? (2016 Feb)Nielsen CHArch Toxicol
29109506Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship. (2017 Nov 6)Marabita FSci Rep
28662467Locus-specific DNA methylation changes and phenotypic variability in children with attention-deficit hyperactivity disorder. (2017 Oct)Sengupta SMPsychiatry Res
23036591Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis. (2012 Oct 4)Kazantseva MGArthritis Res Ther
28436623MTHFR methylation moderates the impact of smoking on DNA methylation at AHRR for African American young adults. (2017 Sep)Beach SRHAm J Med Genet B Neuropsychiatr Genet
29348151AHRR hypomethylation, lung function, lung function decline and respiratory symptoms. (2018 Mar)Kodal JBEur Respir J
24270552Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy. (2014 Mar)Novakovic BEpigenetics
24485148Differences in smoking associated DNA methylation patterns in South Asians and Europeans. (2014 Feb 3)Elliott HRClin Epigenetics
29169084Changes in first trimester fetal CYP1A1 and AHRR DNA methylation and mRNA expression in response to exposure to maternal cigarette smoking. (2018 Jan)Fa SEnviron Toxicol Pharmacol
22232023Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. (2012 Mar)Monick MMAm J Med Genet B Neuropsychiatr Genet
25862628DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring. (2015 Aug)Kupers LKInt J Epidemiol
27632354DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk. (2017 Jan 1)Baglietto LInt J Cancer
26356606Smoking, Methylation at AHRR, and Recidivism Risk in a Community Correction Sample of Individuals at High Risk for Recidivism. (2015 Oct)Gunter TDBehav Sci Law
18062829Effect of long-term selenium yeast intervention on activity and gene expression of antioxidant and xenobiotic metabolising enzymes in healthy elderly volunteers from the Danish Prevention of Cancer by Intervention by Selenium (PRECISE) pilot study. (2008 Jun)Ravn-Haren GBr J Nutr
23175441Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking. (2013 Mar 1)Shenker NSHum Mol Genet
29047347The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers. (2017 Oct 18)Wilson RBMC Genomics
27092088Reversion of AHRR Demethylation Is a Quantitative Biomarker of Smoking Cessation. (2016)Philibert RFront Psychiatry
29326313DNA Methylation and Age-Independent Cardiovascular Risk, an Epigenome-Wide Approach: The REGICOR Study (REgistre GIroni del COR). (2018 Mar)Fernandez-Sanles AArterioscler Thromb Vasc Biol
29456763Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study. (2018)Li SClin Epigenetics
26478754DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies. (2015)Gao XClin Epigenetics
29618728Association between DNA methylation in cord blood and maternal smoking: The Hokkaido Study on Environment and Children's Health. (2018 Apr 4)Miyake KSci Rep
29695247Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation. (2018 Apr 25)Witt SHBMC Genomics
26580635Assessment of Offspring DNA Methylation across the Lifecourse Associated with Prenatal Maternal Smoking Using Bayesian Mixture Modelling. (2015 Nov 13)de Vocht FInt J Environ Res Public Health