Gene info: ID 57685

SNP ID	Position	Alleles	Trait	Variation Type
rs17126643	chr1:64544923 (GRCh38.p7)	T>G	alcohol dependence	SNV(Single Nucleotide Variation)

Gene Symbol	Pearson Correlation Coefficient
DOCK7	0.87
PITPNC1	0.86
OPHN1	0.856
BCL2	0.85
MAP3K5	0.835
TMEM164	0.834
ACOX1	0.83
SLC41A1	0.826
NTRK2	0.82
SLC1A3	0.818

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.435
OR4F29	-0.404
SULT2B1	-0.321
CETP	-0.296
QRFPR	-0.285
GPD1	-0.279
PTPRH	-0.271
DUSP27	-0.262
OR6C74	-0.261
CDH1	-0.255

DrugBank
CTD

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CACHD1 mRNA"	19114083
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
D000082	Acetaminophen	Acetaminophen results in decreased expression of CACHD1 mRNA	26690555
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of CACHD1 mRNA	19770486
C015001	arsenite	arsenite results in decreased methylation of CACHD1 promoter	23974009
C547126	AZM551248	AZM551248 results in decreased expression of CACHD1 mRNA	22323515
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CACHD1 mRNA	19770486
D004958	Estradiol	EGF protein inhibits the reaction [Estradiol results in decreased expression of CACHD1 mRNA]	24758408
D004958	Estradiol	Estradiol results in decreased expression of CACHD1 mRNA	24758408
C006780	bisphenol A	bisphenol A results in decreased expression of CACHD1 mRNA	25181051
D002220	Carbamazepine	Carbamazepine affects the expression of CACHD1 mRNA	25979313
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of CACHD1 mRNA	17484886
D020245	p-Chloromercuribenzoic Acid	p-Chloromercuribenzoic Acid results in decreased expression of CACHD1 mRNA	26272509
D003300	Copper	[NSC 689534 binds to Copper] which results in decreased expression of CACHD1 mRNA	20971185
D003471	Cuprizone	Cuprizone results in increased expression of CACHD1 mRNA	26577399
D016572	Cyclosporine	Cyclosporine results in decreased expression of CACHD1 mRNA	20106945\|2798913
D016572	Cyclosporine	Cyclosporine results in increased expression of CACHD1 mRNA	19770486
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in increased expression of CACHD1 mRNA	23914054
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in decreased expression of CACHD1 mRNA	27392435
D002945	Cisplatin	Cisplatin results in decreased expression of CACHD1 mRNA	27392435
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of CACHD1 mRNA	17555576
C069837	fullerene C60	fullerene C60 affects the expression of CACHD1 mRNA	19167457
D017313	Fenretinide	Fenretinide results in decreased expression of CACHD1 mRNA	28973697
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in decreased expression of CACHD1 mRNA	27392435
C544151	jinfukang	jinfukang results in decreased expression of CACHD1 mRNA	27392435
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in increased expression of CACHD1 mRNA	24796395
D007854	Lead	Lead affects the splicing of CACHD1 mRNA	28903495
C482199	lipopolysaccharide, E coli O55-B5	"lipopolysaccharide, E coli O55-B5 results in increased expression of CACHD1 mRNA"	24972896
C042720	mercuric bromide	mercuric bromide results in decreased expression of CACHD1 mRNA	26272509
C042720	mercuric bromide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
C004925	methylmercuric chloride	methylmercuric chloride results in decreased expression of CACHD1 mRNA	28001369
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of CACHD1 mRNA	26011545
C028007	nickel monoxide	nickel monoxide results in decreased expression of CACHD1 mRNA	19167457
C029938	nickel sulfate	nickel sulfate results in increased expression of CACHD1 mRNA	22714537
C558013	NSC 689534	[NSC 689534 binds to Copper] which results in decreased expression of CACHD1 mRNA	20971185
D010416	Pentachlorophenol	Pentachlorophenol results in increased expression of CACHD1 mRNA	23892564
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CACHD1 mRNA	19710929
D012715	Sesame Oil	Sesame Oil results in increased expression of CACHD1 mRNA	29191790
C017947	sodium arsenite	sodium arsenite results in increased expression of CACHD1 mRNA	22714537
D013629	Tamoxifen	Tamoxifen affects the expression of CACHD1 mRNA	17555576
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CACHD1 mRNA	19770486
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
C012589	trichostatin A	trichostatin A results in decreased expression of CACHD1 mRNA	24935251\|2627250
C015559	trimellitic anhydride	trimellitic anhydride results in decreased expression of CACHD1 mRNA	19042947
D014520	Urethane	Urethane results in increased expression of CACHD1 mRNA	28818685
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CACHD1 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid results in decreased expression of CACHD1 mRNA	24383497\|2627250
D014635	Valproic Acid	Valproic Acid results in increased expression of CACHD1 mRNA	23179753\|2718838
D014638	Vanadates	Vanadates results in decreased expression of CACHD1 mRNA	22714537
C029297	vinylidene chloride	vinylidene chloride results in decreased expression of CACHD1 mRNA	26682919

Gene: CACHD1

ANCO-SNPs

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Drugs/Compounds

There is no DrugBank record for this gene !

GO/Pathway

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)