| SNP ID | Position | Alleles | Trait | Variation Type |
|---|---|---|---|---|
| rs544475121 | chr13:48442207-48442218 (GRCh38.p7) | delT | alcohol dependence | Indel(Insertion and Deletion) |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| CD164 | 0.893 |
| COPB1 | 0.885 |
| RAB8B | 0.882 |
| TNPO1 | 0.881 |
| SP3 | 0.88 |
| NCK1 | 0.875 |
| MBNL1 | 0.875 |
| AIDA | 0.871 |
| UBE2J1 | 0.866 |
| ERP44 | 0.865 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| OR4F5 | -0.57 |
| OR4F29 | -0.528 |
| HES5 | -0.258 |
| ARSF | -0.195 |
| NTN5 | -0.181 |
| TPPP2 | -0.173 |
| SPRR2A | -0.17 |
| BTBD17 | -0.162 |
| TCL1A | -0.159 |
| GH1 | -0.149 |
| ID | Drug Name | Drug Type | CAS Num | Status | Role |
|---|---|---|---|---|---|
| DB00030 | Insulin Human | BiotechDrug | 11061-68-0 | Approved|Investigational | Target |
| DB00071 | Insulin Pork | BiotechDrug | 12584-58-6 | Approved | Target |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| C492909 | 1,1-bis(3'-indolyl)-1-(4-trifluoromethylphenyl)methane | "1,1-bis(3'-indolyl)-1-(4-trifluoromethylphenyl)methane results in decreased phosphorylation of RB1 protein" | 15345676 |
| C044985 | 1',2'-dihydrorotenone | "1',2'-dihydrorotenone results in decreased phosphorylation of RB1 protein" | 24615755 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of RB1 protein" | 15382178 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased phosphorylation of RB1 protein" | 12807759|2368455 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "[Tetrachlorodibenzodioxin co-treated with 1,4-bis(2-(3,5-dichloropyridyloxy))benzene] results in increased phosphorylation of RB1 protein" | 20637255 |
| C097240 | 15-deoxy-delta(12,14)-prostaglandin J2 | "15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of and results in decreased expression of RB1 protein" | 15729575 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of RB1 protein" | 20453058 |
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in increased expression of RB1 mRNA" | 26988655 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of RB1 mRNA] | 14729647 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Paclitaxel results in increased phosphorylation of RB1 protein] | 15138593 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tamoxifen results in decreased phosphorylation of RB1 protein] | 14645110 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [TNF protein results in increased phosphorylation of RB1 protein] | 17273796 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased phosphorylation of RB1 protein | 14516785 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of RB1 protein] | 21813366 |
| C016403 | 2,4-dinitrotoluene | "2,4-dinitrotoluene affects the expression of RB1 mRNA" | 21346803 |
| C439584 | 2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol | 2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol results in decreased phosphorylation of RB1 protein | 16954435 |
| C439584 | 2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol | temsirolimus promotes the reaction [2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol results in decreased phosphorylation of RB1 protein] | 16954435 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | [Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [IL2 protein results in increased phosphorylation of RB1 protein] | 15778701 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vanadates results in increased phosphorylation of RB1 protein] | 14971663 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of RB1 protein | 15601625 |
| C089946 | 2,4-thiazolidinedione | "2,4-thiazolidinedione results in decreased expression of RB1 protein" | 15916743 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased phosphorylation of RB1 protein" | 15635149 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RB1 protein modified form" | 14522882 |
| C521501 | 2-bromo-12,13-dihydro-5-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione | "2-bromo-12,13-dihydro-5-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione promotes the reaction [MRK 003 results in decreased phosphorylation of and results in increased activity of RB1 protein]" | 19318552 |
| C000589290 | 2-hydroxy-1-(2-((9-(4-methylcyclohexyl)-9H-pyrido(4',3'-4,5)pyrrolo(2,3-d)pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethanone | "2-hydroxy-1-(2-((9-(4-methylcyclohexyl)-9H-pyrido(4',3'-4,5)pyrrolo(2,3-d)pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethanone results in decreased phosphorylation of RB1 protein" | 24526162 |
| C120275 | 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone | 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased phosphorylation of RB1 protein | 11468187 |
| C497101 | 2-hydroxy-9-cis-octadecenoic acid | 2-hydroxy-9-cis-octadecenoic acid results in decreased phosphorylation of RB1 protein | 16027227 |
| C019499 | 2-nitrofluorene | 2-nitrofluorene results in decreased expression of RB1 mRNA | 15890375 |
| C560905 | 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione | "3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione results in decreased phosphorylation of RB1 protein" | 21600193 |
| C494914 | 3,5,3',4',5'-pentamethoxystilbene | "[3,5,3',4',5'-pentamethoxystilbene results in decreased activity of CDK4 protein] which results in decreased phosphorylation of RB1 protein" | 19916542 |
| C034534 | 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid | "3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid results in decreased phosphorylation of RB1 protein" | 15475462 |
| C034534 | 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid | "(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride promotes the reaction [3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid results in decreased phosphorylation of RB1 protein]" | 15475462 |
| C025160 | 3-aminobenzamide | 3-aminobenzamide promotes the reaction [RB1 protein binds to E2F1 protein] | 15670817 |
| C025160 | 3-aminobenzamide | 3-aminobenzamide results in decreased phosphorylation of and results in increased activity of RB1 protein | 15670817 |
| C015392 | 3-nitropropionic acid | 3-nitropropionic acid results in decreased expression of RB1 protein | 21827787 |
| C038864 | 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid | "4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased phosphorylation of RB1 protein]" | 11348869 |
| C038864 | 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid | "4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]" | 12421932 |
| C038864 | 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid | "4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased phosphorylation of RB1 protein" | 16273314 |
| C088860 | 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline | "4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]" | 24639330 |
| C088860 | 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline | "4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 protein]" | 24639330 |
| C090942 | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Calcitriol results in increased expression of RB1 mRNA] | 14729647 |
| C090942 | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| C119130 | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RB1 protein] | 18805435 |
| C119130 | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in increased phosphorylation of RB1 protein] | 18805435 |
| C027576 | 4-hydroxy-2-nonenal | 4-hydroxy-2-nonenal results in decreased phosphorylation of RB1 protein | 15607904 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RB1 protein] | 18805435 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RB1 protein | 18805435 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RB1 mRNA | 15890375 |
| C546624 | (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol | "(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol affects the reaction [N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide affects the phosphorylation of and affects the expression of RB1 protein]" | 24444656 |
| C513935 | 5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide | "5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide results in decreased phosphorylation of RB1 protein" | 17537993 |
| C439285 | (5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride | "(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride promotes the reaction [3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid results in decreased phosphorylation of RB1 protein]" | 15475462 |
| C510786 | 5-nitroso-8-quinolinol | 5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form | 16497787 |
| C510786 | 5-nitroso-8-quinolinol | Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form] | 16497787 |
| C580598 | 5-OH-BDE-47 | 5-OH-BDE-47 results in increased expression of RB1 mRNA | 26988655 |
| C560597 | 6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide | "6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [methoxyacetic acid results in increased phosphorylation of RB1 protein]" | 21573189 |
| C107875 | 6-(methylamino)pyrido(3,4-d)pyrimidine | "6-(methylamino)pyrido(3,4-d)pyrimidine results in decreased phosphorylation of RB1 protein" | 15572027 |
| C531937 | 6-O-angeloylenolin | 6-O-angeloylenolin results in decreased expression of RB1 protein modified form | 21192922 |
| C559145 | 7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine | "7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine results in decreased phosphorylation of RB1 protein" | 21417417 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in decreased phosphorylation of RB1 protein | 14653808 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in increased expression of RB1 mRNA | 14653808 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in increased expression of RB1 protein | 14653808 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in increased stability of RB1 protein | 14653808 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in increased expression of RB1 mRNA | 14653808 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in increased expression of RB1 protein | 14653808 |
| C072876 | A 771726 | A 771726 results in decreased expression of RB1 protein | 19174558 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of RB1 mRNA | 22230336 |
| D000082 | Acetaminophen | Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein] | 28123000 |
| D000082 | Acetaminophen | Acetaminophen results in increased phosphorylation of RB1 protein | 28123000 |
| D000082 | Acetaminophen | Canertinib inhibits the reaction [Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein]] | 28123000 |
| D000082 | Acetaminophen | Canertinib inhibits the reaction [Acetaminophen results in increased phosphorylation of RB1 protein] | 28123000 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form] | 16497787 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein] | 22927544 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Levamisole results in decreased expression of RB1 protein] | 11139434 |
| D000157 | Aconitine | Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | 16862215 |
| D020106 | Acrylamide | Acrylamide results in increased expression of RB1 mRNA | 28959563 |
| C096064 | actein | actein results in decreased expression of RB1 protein | 14758092 |
| C058956 | acteoside | acteoside results in decreased phosphorylation of RB1 protein | 17634406 |
| C058956 | acteoside | [acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein] | 17634406 |
| D017500 | Adenovirus E1A Proteins | Adenovirus E1A Proteins binds to RB1 protein | 19523934 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of RB1 gene | 27153756 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of RB1 mRNA | 19770486 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased expression of RB1 mRNA | 15890375 |
| C430898 | AGN 194204 | AGN 194204 inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased phosphorylation of RB1 protein] | 11348869 |
| D000395 | Air Pollutants, Occupational | "Air Pollutants, Occupational results in decreased expression of RB1 mRNA" | 23195993 |
| D000420 | Albuterol | Albuterol results in decreased expression of RB1 protein | 16446544 |
| D000420 | Albuterol | Albuterol results in increased expression of RB1 protein | 18362475 |
| D000420 | Albuterol | ICI 118551 inhibits the reaction [Albuterol results in decreased expression of RB1 protein] | 16446544 |
| C103303 | alitretinoin | alitretinoin inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased phosphorylation of RB1 protein] | 11348869 |
| C103303 | alitretinoin | alitretinoin results in decreased phosphorylation of RB1 protein | 16273314 |
| C510660 | alopestatin | alopestatin analog results in decreased phosphorylation of RB1 protein | 16525630 |
| D013196 | Dihydrotestosterone | Dihydrotestosterone results in decreased phosphorylation of RB1 protein | 15322241 |
| D013196 | Dihydrotestosterone | Dihydrotestosterone results in increased phosphorylation of RB1 protein | 15647840 |
| C040534 | alpha-hexachlorocyclohexane | alpha-hexachlorocyclohexane affects the expression of RB1 mRNA | 16940010 |
| C040534 | alpha-hexachlorocyclohexane | alpha-hexachlorocyclohexane results in decreased expression of RB1 mRNA | 16940010 |
| C040534 | alpha-hexachlorocyclohexane | alpha-hexachlorocyclohexane results in increased expression of RB1 mRNA | 16940010 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] | 15157999 |
| C077990 | alvocidib | alvocidib results in decreased activity of RB1 protein modified form | 10441105 |
| C077990 | alvocidib | alvocidib results in decreased expression of RB1 protein | 9829756 |
| C077990 | alvocidib | alvocidib results in decreased expression of RB1 protein modified form | 16905211 |
| C077990 | alvocidib | alvocidib results in decreased phosphorylation of RB1 protein | 15180955 |
| C077990 | alvocidib | [docetaxel co-treated with alvocidib] results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15297405 |
| C077990 | alvocidib | RB1 results in decreased susceptibility to alvocidib | 9829756 |
| C077990 | alvocidib | alvocidib results in decreased phosphorylation of RB1 protein | 15180955 |
| C068073 | Am 580 | [Am 580 co-treated with Retinoids] results in decreased phosphorylation of RB1 protein | 15383624 |
| D017311 | Amlodipine | Amlodipine results in decreased phosphorylation of RB1 protein | 17217918 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of RB1 mRNA | 16483693 |
| D000655 | Amodiaquine | Amodiaquine affects the phosphorylation of RB1 protein | 24113242 |
| C030419 | andrographolide | andrographolide results in decreased phosphorylation of RB1 protein | 18619950 |
| C023650 | aniline | aniline results in increased phosphorylation of RB1 protein | 21070798 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in decreased expression of RB1 mRNA | 24449571 |
| C101577 | apo-12'-carotenoic acid | apo-12'-carotenoic acid results in decreased expression of RB1 protein | 12042460 |
| C483690 | apo-14'-carotenoic acid | apo-14'-carotenoic acid results in decreased expression of RB1 protein | 12042460 |
| C050510 | arsenic trichloride | arsenic trichloride results in increased phosphorylation of RB1 protein | 16283526 |
| C006632 | arsenic trioxide | [arsenic trioxide results in decreased activity of CDK6 protein] which results in decreased phosphorylation of RB1 protein | 10850458 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of RB1 protein modified form | 20953137 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased phosphorylation of RB1 protein | 12480548|2533511 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite affects the expression of RB1 mRNA" | 17331233 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite results in decreased expression of RB1 protein modified form" | 21570478 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite results in decreased phosphorylation of RB1 protein" | 15374964 |
| C010302 | aspidin BB | aspidin BB results in increased expression of RB1 protein | 23628508 |
| D001241 | Aspirin | Aspirin inhibits the reaction [troglitazone results in decreased expression of RB1 protein modified form] | 19908241 |
| D001241 | Aspirin | Aspirin promotes the reaction [troglitazone results in increased expression of RB1 protein] | 19908241 |
| D001241 | Aspirin | Aspirin results in decreased expression of RB1 protein modified form | 19908241 |
| D001241 | Aspirin | Aspirin results in increased expression of RB1 protein | 19908241 |
| D001241 | Aspirin | troglitazone inhibits the reaction [Aspirin results in decreased expression of RB1 protein modified form] | 19908241 |
| D001241 | Aspirin | troglitazone promotes the reaction [Aspirin results in increased expression of RB1 protein] | 19908241 |
| D000069059 | Atorvastatin Calcium | [Atorvastatin Calcium co-treated with Celecoxib] results in decreased expression of RB1 protein modified form | 18172863 |
| D000069059 | Atorvastatin Calcium | [Atorvastatin Calcium co-treated with Celecoxib] results in increased expression of RB1 protein | 18172863 |
| D001280 | Atrazine | Atrazine affects the expression of RB1 mRNA | 25929836 |
| D001310 | Auranofin | Auranofin results in decreased phosphorylation of RB1 protein | 20542334 |
| C006680 | baicalein | AHR protein affects the reaction [baicalein results in decreased phosphorylation of RB1 protein] | 22820424 |
| C006680 | baicalein | baicalein results in decreased phosphorylation of RB1 protein | 22820424 |
| C006680 | baicalein | Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein] | 22820424 |
| D001507 | Beclomethasone | Beclomethasone results in decreased expression of RB1 mRNA | 23656298 |
| D001554 | Benzene | Benzene results in increased expression of RB1 protein | 20850422 |
| D001554 | Benzene | Benzene results in increased expression of RB1 protein modified form | 20850422 |
| D001554 | Benzene | Benzene results in increased phosphorylation of RB1 protein | 9118908 |
| D019324 | beta-Naphthoflavone | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RB1 mRNA | 18164116 |
| D019324 | beta-Naphthoflavone | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RB1 mRNA | 18164116 |
| D053119 | Benzophenanthridines | Benzophenanthridines analog results in decreased expression of RB1 mRNA | 23117580 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of RB1 protein | 20850422 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of RB1 protein modified form | 20850422 |
| D001564 | Benzo(a)pyrene | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RB1 mRNA] | 22228805 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of RB1 mRNA | 22228805 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of RB1 mRNA | 19770486|2222880 |
| D001564 | Benzo(a)pyrene | AHR affects the reaction [Benzo(a)pyrene results in increased phosphorylation of RB1 protein] | 17141280 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of RB1 mRNA | 19408242|2006408 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of RB1 protein | 20064080 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of RB1 protein | 19408242|2146774 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased phosphorylation of RB1 protein | 17141280 |
| D001564 | Benzo(a)pyrene | [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA | 19408242 |
| D001564 | Benzo(a)pyrene | [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 protein | 19408242 |
| D001564 | Benzo(a)pyrene | Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 mRNA] | 20064080 |
| D001564 | Benzo(a)pyrene | Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 protein] | 20064080 |
| D004958 | Estradiol | Estradiol results in decreased expression of RB1 mRNA | 19027819 |
| D004958 | Estradiol | Estradiol results in increased phosphorylation of RB1 protein | 15297603|9049186 |
| D004958 | Estradiol | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein] | 9705214 |
| D004958 | Estradiol | Estradiol results in increased phosphorylation of RB1 protein | 15845746|2368455 |
| D004958 | Estradiol | Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]] | 15845746 |
| D004958 | Estradiol | Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein] | 15845746 |
| C044887 | beta-methylcholine | beta-methylcholine affects the expression of RB1 mRNA | 21179406 |
| C095105 | bexarotene | bexarotene results in decreased phosphorylation of RB1 protein | 16273314 |
| C053541 | bicalutamide | bicalutamide results in increased phosphorylation of RB1 protein | 17599054 |
| C070515 | bisindolylmaleimide I | bisindolylmaleimide I results in increased expression of RB1 protein | 14653808 |
| C070515 | bisindolylmaleimide I | bisindolylmaleimide I results in increased expression of RB1 mRNA | 14653808 |
| C070515 | bisindolylmaleimide I | bisindolylmaleimide I results in increased expression of RB1 protein | 14653808 |
| C006780 | bisphenol A | bisphenol A affects the expression of RB1 mRNA | 21786754 |
| C006780 | bisphenol A | bisphenol A results in decreased activity of RB1 protein | 19654912 |
| C006780 | bisphenol A | bisphenol A results in increased phosphorylation of RB1 protein | 19654912|2322281 |
| C006780 | bisphenol A | Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of RB1 protein] | 23222814 |
| C006780 | bisphenol A | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of RB1 protein] | 21813366 |
| C006780 | bisphenol A | bisphenol A affects the methylation of RB1 promoter | 27334623 |
| C006780 | bisphenol A | bisphenol A results in increased phosphorylation of and results in increased activity of RB1 protein | 21813366 |
| C006780 | bisphenol A | Pertussis Toxin inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of RB1 protein] | 21813366 |
| C006780 | bisphenol A | bisphenol A results in increased expression of RB1 mRNA | 25181051 |
| C492810 | BL1521 | BL1521 results in decreased phosphorylation of RB1 protein | 15733867 |
| C545990 | BMS 754807 | BMS 754807 promotes the reaction [palbociclib results in decreased phosphorylation of RB1 protein] | 24986516 |
| C545990 | BMS 754807 | BMS 754807 results in decreased phosphorylation of RB1 protein | 24986516 |
| C545990 | BMS 754807 | RB1 mutant form results in decreased susceptibility to BMS 754807 | 24986516 |
| D000069286 | Bortezomib | [Bortezomib co-treated with Butyrates] results in increased degradation of RB1 protein | 12893773 |
| D000069286 | Bortezomib | [Bortezomib co-treated with vorinostat] results in increased degradation of RB1 protein | 12893773 |
| D000069286 | Bortezomib | [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased phosphorylation of RB1 protein | 25522274 |
| D000069286 | Bortezomib | RB1 mutant form results in increased susceptibility to Bortezomib | 25522274 |
| D000069286 | Bortezomib | [RB1 mutant form results in increased susceptibility to Bortezomib] which results in increased cleavage of PARP1 protein | 25522274 |
| D000069286 | Bortezomib | TP53BP1 protein affects the reaction [[BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased phosphorylation of RB1 protein] | 25522274 |
| C023623 | brassinolide | brassinolide results in decreased expression of RB1 protein | 20833159 |
| C023623 | brassinolide | brassinolide results in decreased expression of RB1 protein modified form | 20833159 |
| D002038 | Bungarotoxins | Bungarotoxins inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | 16862215 |
| C073829 | Bupleuran 2IIc | Bupleuran 2IIc results in increased phosphorylation of RB1 protein | 14556967 |
| D002065 | Buspirone | Buspirone results in decreased expression of RB1 mRNA | 24136188 |
| D002066 | Busulfan | Busulfan results in decreased phosphorylation of RB1 protein | 15388331 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in decreased expression of RB1 mRNA | 12419474|1533650 |
| C026105 | butylidenephthalide | butylidenephthalide results in decreased phosphorylation of RB1 protein | 16987298 |
| C026105 | butylidenephthalide | butylidenephthalide results in decreased phosphorylation of RB1 protein | 16987298 |
| D002087 | Butyrates | [Bortezomib co-treated with Butyrates] results in increased degradation of RB1 protein | 12893773 |
| D002087 | Butyrates | Butyrates results in decreased expression of and results in decreased phosphorylation of RB1 protein | 15177505 |
| D002087 | Butyrates | Butyrates results in decreased expression of RB1 mRNA | 16042588 |
| D002087 | Butyrates | Butyrates results in decreased phosphorylation of RB1 protein | 14707268 |
| D020148 | Butyric Acid | [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein | 25070040 |
| D020148 | Butyric Acid | [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein | 25070040 |
| C028031 | cadmium acetate | cadmium acetate promotes the reaction [RB1 protein modified form binds to E2F1 protein] | 20839231 |
| C028031 | cadmium acetate | cadmium acetate results in decreased expression of RB1 mRNA | 20839231 |
| C028031 | cadmium acetate | cadmium acetate results in decreased phosphorylation of RB1 protein | 20839231 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of RB1 mRNA | 1626475 |
| C055494 | caffeic acid phenethyl ester | caffeic acid phenethyl ester results in decreased expression of RB1 protein modified form | 15885897 |
| D002110 | Caffeine | Caffeine results in decreased phosphorylation of RB1 protein | 21229324 |
| D002110 | Caffeine | Caffeine results in decreased phosphorylation of RB1 protein | 15126379 |
| C031938 | calmidazolium | calmidazolium results in decreased phosphorylation of RB1 protein | 12901840|1570843 |
| C059041 | calyculin A | calyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RB1 protein] | 12621062 |
| D002166 | Camptothecin | Camptothecin results in increased phosphorylation of RB1 protein | 15585644 |
| D002166 | Camptothecin | RB1 protein affects the susceptibility to Camptothecin | 14704340 |
| D002166 | Camptothecin | Camptothecin results in increased phosphorylation of RB1 protein | 14647467 |
| D002166 | Camptothecin | RB1 protein affects the susceptibility to Camptothecin | 15064736 |
| C420268 | Canertinib | Canertinib inhibits the reaction [Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein]] | 28123000 |
| C420268 | Canertinib | Canertinib inhibits the reaction [Acetaminophen results in increased phosphorylation of RB1 protein] | 28123000 |
| D000069287 | Capecitabine | RB1 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] | 18678097 |
| D002211 | Capsaicin | [Capsaicin results in decreased expression of CCND1] inhibits the reaction [CDK4 results in increased phosphorylation of RB1 protein] | 14744780 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of RB1 mRNA | 24752500 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of RB1 mRNA | 15056808 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased phosphorylation of RB1 protein | 12759355 |
| D002251 | Carbon Tetrachloride | CDKN1A protein affects the reaction [Carbon Tetrachloride results in increased phosphorylation of RB1 protein] | 12759355 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased phosphorylation of RB1 protein | 17256749 |
| C111238 | carboxycinnamic acid bishydroxamide | carboxycinnamic acid bishydroxamide results in increased expression of RB1 protein | 15897598 |
| C103436 | CB 1093 | CB 1093 results in decreased phosphorylation of RB1 protein | 12907249 |
| D000068579 | Celecoxib | [Atorvastatin Calcium co-treated with Celecoxib] results in decreased expression of RB1 protein modified form | 18172863 |
| D000068579 | Celecoxib | [Atorvastatin Calcium co-treated with Celecoxib] results in increased expression of RB1 protein | 18172863 |
| D000068579 | Celecoxib | Celecoxib results in increased expression of RB1 | 19846907 |
| D002509 | Cephaloridine | Cephaloridine affects the activity of RB1 protein | 18500788 |
| D002518 | Ceramides | Ceramides results in decreased phosphorylation of RB1 protein | 9716505 |
| D002518 | Ceramides | Ceramides results in decreased phosphorylation of RB1 protein | 15361069 |
| C030816 | chloramine | chloramine results in decreased phosphorylation of RB1 protein | 14959856 |
| D002706 | Chlordan | Chlordan results in decreased expression of RB1 protein | 10048758 |
| C074702 | chromium hexavalent ion | AKT1 protein affects the reaction [Vanadates inhibits the reaction [chromium hexavalent ion affects the localization of RB1 protein]] | 19377290 |
| C074702 | chromium hexavalent ion | AKT1 protein modified form inhibits the reaction [chromium hexavalent ion affects the localization of RB1 protein] | 19377290 |
| C074702 | chromium hexavalent ion | chromium hexavalent ion affects the localization of RB1 protein | 19377290 |
| C074702 | chromium hexavalent ion | Vanadates inhibits the reaction [chromium hexavalent ion affects the localization of RB1 protein] | 19377290 |
| C043867 | cicaprost | cicaprost results in decreased phosphorylation of RB1 protein | 12869629 |
| D002995 | Clofibric Acid | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RB1 mRNA | 17602206 |
| D003078 | Colchicine | Colchicine results in decreased phosphorylation of and results in decreased activity of RB1 protein | 16495211 |
| D005576 | Colforsin | [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein] | 9454737 |
| D003300 | Copper | Copper affects the expression of RB1 mRNA | 16246896 |
| D003300 | Copper | Copper results in increased expression of RB1 mRNA | 16391388 |
| C477330 | CP-654577 | CP-654577 results in decreased phosphorylation of RB1 protein | 12907618 |
| C539572 | CpG-ODN DSP30 | [CpG-ODN DSP30 co-treated with IL2 protein] results in increased expression of RB1 protein | 17805332 |
| C539572 | CpG-ODN DSP30 | teriflunomide inhibits the reaction [[CpG-ODN DSP30 co-treated with IL2 protein] results in increased expression of RB1 protein] | 17805332 |
| C408982 | CPG-oligonucleotide | CPG-oligonucleotide results in increased phosphorylation of RB1 protein | 17209053 |
| C408982 | CPG-oligonucleotide | Tretinoin promotes the reaction [CPG-oligonucleotide results in increased phosphorylation of RB1 protein] | 17209053 |
| C542041 | cudraflavone B | cudraflavone B results in decreased phosphorylation of RB1 protein | 23881456 |
| C542041 | cudraflavone B | resveratrol inhibits the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein] | 23881456 |
| C542041 | cudraflavone B | sirtinol promotes the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein] | 23881456 |
| C015763 | cumene | [cumene co-treated with KRAS gene mutant form] results in decreased expression of RB1 mRNA | 18648096 |
| D003474 | Curcumin | Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of RB1 protein] | 23222814 |
| D003474 | Curcumin | Curcumin results in decreased phosphorylation of RB1 protein | 18156803|2322281 |
| D003474 | Curcumin | Curcumin results in decreased phosphorylation of RB1 protein | 15738001 |
| C109140 | CVT 313 | CVT 313 inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] | 21880723 |
| C109140 | CVT 313 | CVT 313 results in decreased phosphorylation of RB1 protein | 21880723 |
| D003513 | Cycloheximide | RB1 protein affects the reaction [palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]] | 20100483 |
| C013905 | cyclopentenone | cyclopentenone results in decreased phosphorylation of RB1 protein | 16061222 |
| D003545 | Cysteine | Cysteine analog results in decreased phosphorylation of RB1 protein | 15890017 |
| C531198 | dactolisib | dactolisib results in decreased expression of RB1 protein modified form | 23651616 |
| D003630 | Daunorubicin | Daunorubicin results in increased expression of RB1 mRNA | 12656675 |
| D003634 | DDT | DDT results in increased phosphorylation of RB1 protein | 9049186 |
| D003634 | DDT | DDT results in increased phosphorylation of RB1 protein | 23684557 |
| C014347 | decitabine | [decitabine affects the expression of DNMT3B protein] which affects the expression of RB1 mRNA | 18544619 |
| C014347 | decitabine | decitabine results in decreased expression of RB1 mRNA | 19027819 |
| C014347 | decitabine | decitabine results in decreased phosphorylation of RB1 protein | 12859993 |
| D003676 | Deferoxamine | Deferoxamine results in decreased phosphorylation of RB1 protein | 11468187 |
| C107676 | deguelin | deguelin results in decreased expression of RB1 protein | 15960896 |
| D003687 | Dehydroepiandrosterone | Dehydroepiandrosterone results in decreased expression of and results in decreased phosphorylation of RB1 protein | 15752352 |
| D003687 | Dehydroepiandrosterone | Dehydroepiandrosterone results in increased expression of RB1 mRNA | 16940010 |
| D003907 | Dexamethasone | Dexamethasone results in increased phosphorylation of RB1 protein | 16510457 |
| D003907 | Dexamethasone | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein | 25559859 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of RB1 mRNA | 21041162 |
| D003907 | Dexamethasone | silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein] | 25559859 |
| D003907 | Dexamethasone | Dexamethasone inhibits the reaction [CDK2 protein results in increased phosphorylation of RB1 protein] | 9442036 |
| D003907 | Dexamethasone | Dexamethasone results in decreased phosphorylation of RB1 protein | 9442036 |
| D003907 | Dexamethasone | Dexamethasone results in increased activity of RB1 protein | 19158320 |
| D003976 | Diazinon | Diazinon affects the expression of RB1 mRNA | 22546817 |
| C100805 | DIBA-1 | DIBA-1 results in increased expression of RB1 mRNA | 14702633 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased phosphorylation of RB1 protein | 16916955 |
| D003994 | Bucladesine | Bucladesine inhibits the reaction [CASP3 protein results in increased cleavage of RB1 protein] | 10697531 |
| D003994 | Bucladesine | Bucladesine results in decreased activity of RB1 protein | 10697531 |
| D003994 | Bucladesine | Bucladesine results in decreased phosphorylation of RB1 protein | 16718685 |
| D002945 | Cisplatin | RB1 protein affects the susceptibility to Cisplatin | 14704340|1764066 |
| D002945 | Cisplatin | Cisplatin results in increased expression of RB1 mRNA | 21151649 |
| D004008 | Diclofenac | Diclofenac affects the expression of RB1 mRNA | 24752500 |
| D001728 | Dicumarol | Dicumarol results in increased phosphorylation of RB1 protein | 15896341 |
| D004026 | Dieldrin | Dieldrin affects the expression of RB1 mRNA | 22546817 |
| D004052 | Diethylnitrosamine | RB1 protein affects the reaction [Diethylnitrosamine results in increased expression of RBL1 protein] | 19887370 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AEBP2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ANAPC5 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ANGPTL2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ANLN mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASF1B mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATM mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AURKA mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BIRC5 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BRCA1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BRCA2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BUB1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CASP8AP2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CBX5 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNA2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNA2 protein] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNB1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNB2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNF mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC20 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC25C mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC45 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC6 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA3 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA5 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA7 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA8 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDK1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDKN1C mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDT1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CENPA mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHAF1B mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CKAP2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CKS1B mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CKS2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CRABP1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DCK mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DEK mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNAJC9 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNM1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNMT1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DOK1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DTYMK mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of E2F1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of E2F1 protein] | 17854601|1988737 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ECT2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EGR1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EI24 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPHX1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ERCC5 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ETV4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EZH2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FBLN1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FEN1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FEZ1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FIGNL1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FOXM1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of GJA1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of GMNN mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HAT1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HMGA2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HMGB2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HMGB3 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HMGN1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HMGN2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HNRNPU mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IDH2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of INCENP mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF11 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF20A mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF22 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF23 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF2C mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF5A mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of LIG1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of LMO7 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of LTBP4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MAD2L1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MAP4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM3 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM5 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM7 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM7 protein] | 17854601|1988737 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MDM2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MKI67 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MRE11A mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MRE11A protein] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MSH2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MSH2 protein] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of NASP mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of NCAPH mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of NEK2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of NOTCH1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ORC6 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein] | 17854601|1988737 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PERP mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PHC1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLK1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLK4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLTP mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PML mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of POLA1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PRC1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PRDX4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PRIM1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAD21 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAD51AP1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAD51 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBL1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBL1 protein] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RFC1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RFC2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RFC5 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPA1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLK mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of SMC2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of SMC4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of SMOC2 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ST3GAL4 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of STMN1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TCF19 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TFDP1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TIPIN mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TK1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMPO mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TOP2A mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TOPBP1 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TRIP13 mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TTK mRNA] | 17854601 |
| D004052 | Diethylnitrosamine | RB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN2D mRNA] | 18282651 |
| D004052 | Diethylnitrosamine | RB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of TGFB1 mRNA] | 18282651 |
| D004052 | Diethylnitrosamine | RB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CDKN1A mRNA] | 18282651 |
| D004052 | Diethylnitrosamine | RB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of SERPINE1 mRNA] | 18282651 |
| D004052 | Diethylnitrosamine | RB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of TGFB3 mRNA] | 18282651 |
| D004052 | Diethylnitrosamine | RB1 protein results in decreased susceptibility to Diethylnitrosamine | 17854601 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RB1 mRNA | 18164116 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RB1 mRNA | 18164116 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RB1 mRNA | 17602206 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in decreased expression of RB1 mRNA | 19638242 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in increased expression of RB1 protein | 19822196 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of RB1 mRNA | 15545218 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in decreased expression of RB1 mRNA | 15890375 |
| D002117 | Calcitriol | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of RB1 mRNA] | 14729647 |
| D002117 | Calcitriol | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| D002117 | Calcitriol | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Calcitriol results in increased expression of RB1 mRNA] | 14729647 |
| D002117 | Calcitriol | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| D002117 | Calcitriol | Calcitriol results in decreased phosphorylation of RB1 protein | 10825140|1151986 |
| D002117 | Calcitriol | Calcitriol results in decreased phosphorylation of RB1 protein modified form | 11270487 |
| D002117 | Calcitriol | Calcitriol results in increased expression of RB1 mRNA | 14729647 |
| D002117 | Calcitriol | Calcitriol results in increased expression of RB1 protein | 14729647 |
| D002117 | Calcitriol | Calcitriol results in increased expression of RB1 protein modified form | 9348195 |
| D002117 | Calcitriol | CSF1R promotes the reaction [Calcitriol results in decreased phosphorylation of RB1 protein] | 9158000 |
| D002117 | Calcitriol | pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of RB1 mRNA] | 14729647 |
| D002117 | Calcitriol | pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| D002117 | Calcitriol | ZK159222 inhibits the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| D004128 | Dimethylnitrosamine | Dimethylnitrosamine results in decreased expression of RB1 mRNA | 15890375 |
| D004147 | Dioxins | Dioxins results in decreased expression of RB1 mRNA | 15111621 |
| D004221 | Disulfiram | Disulfiram results in decreased expression of RB1 mRNA | 20530235 |
| C067311 | docetaxel | [docetaxel co-treated with alvocidib] results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15297405 |
| D004281 | Docosahexaenoic Acids | Docosahexaenoic Acids results in decreased phosphorylation of RB1 protein | 15560787 |
| D017292 | Doxazosin | Doxazosin results in decreased phosphorylation of RB1 protein | 15371785 |
| D017292 | Doxazosin | Doxazosin affects the phosphorylation of RB1 protein | 18084315 |
| D004317 | Doxorubicin | Acetylcysteine inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein] | 22927544 |
| D004317 | Doxorubicin | Doxorubicin affects the expression of RB1 mRNA | 15205334 |
| D004317 | Doxorubicin | Doxorubicin promotes the reaction [RB1 protein binds to PCNA promoter] | 16537896 |
| D004317 | Doxorubicin | Doxorubicin results in decreased phosphorylation of RB1 protein | 15141020|2292754 |
| D004317 | Doxorubicin | Glutathione inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein] | 22927544 |
| D004317 | Doxorubicin | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]] | 22751436 |
| D004317 | Doxorubicin | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of CCNA2 protein]] | 22751436 |
| D004317 | Doxorubicin | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of E2F1 protein]] | 22751436 |
| D004317 | Doxorubicin | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of TOP2A protein]] | 22751436 |
| D015118 | Eicosapentaenoic Acid | Eicosapentaenoic Acid results in decreased phosphorylation of RB1 protein | 15560787 |
| D004610 | Ellagic Acid | Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA] | 27965107 |
| D004610 | Ellagic Acid | Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] | 27965107 |
| D004642 | Emodin | Emodin results in decreased expression of RB1 mRNA | 16045814 |
| D004726 | Endosulfan | Endosulfan results in decreased phosphorylation of RB1 protein | 26714676 |
| C045651 | epigallocatechin gallate | epigallocatechin gallate results in decreased expression of and results in decreased phosphorylation of RB1 protein | 15142168 |
| C045651 | epigallocatechin gallate | epigallocatechin gallate results in increased expression of RB1 mRNA | 18851785 |
| C498475 | equiguard | equiguard results in decreased phosphorylation of RB1 protein | 15547720 |
| D000069347 | Erlotinib Hydrochloride | Erlotinib Hydrochloride results in decreased phosphorylation of RB1 protein | 21195724 |
| C472787 | erucylphospho-N,N,N-trimethylpropylammonium | "RB1 mutant form inhibits the reaction [erucylphospho-N,N,N-trimethylpropylammonium results in decreased expression of CCND3]" | 24987858 |
| C472787 | erucylphospho-N,N,N-trimethylpropylammonium | "RB1 mutant form inhibits the reaction [erucylphospho-N,N,N-trimethylpropylammonium results in increased expression of CDKN1B]" | 24987858 |
| C472787 | erucylphospho-N,N,N-trimethylpropylammonium | "RB1 protein results in increased susceptibility to erucylphospho-N,N,N-trimethylpropylammonium" | 24987858 |
| D000431 | Ethanol | Ethanol affects the expression of RB1 mRNA | 11772933 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RB1 mRNA | 17942748 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of RB1 mRNA | 16940010 |
| C032773 | ethyl caffeate | ethyl caffeate affects the phosphorylation of RB1 protein | 24892518 |
| C002994 | ethylene dimethanesulfonate | ethylene dimethanesulfonate results in decreased expression of RB1 mRNA | 22711419 |
| C002994 | ethylene dimethanesulfonate | ethylene dimethanesulfonate affects the expression of RB1 protein | 15659706 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in increased expression of RB1 mRNA | 23649840 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased expression of RB1 mRNA | 15954086 |
| D005047 | Etoposide | [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein] | 9454737 |
| D005047 | Etoposide | Etoposide results in decreased phosphorylation of RB1 protein | 9454737 |
| D005047 | Etoposide | RB1 protein affects the susceptibility to Etoposide | 17640669 |
| D005054 | Eugenol | Eugenol results in decreased expression of RB1 protein | 22686307 |
| D000068338 | Everolimus | Everolimus results in decreased phosphorylation of and affects the activity of RB1 protein | 16033851 |
| D000068338 | Everolimus | Everolimus results in decreased phosphorylation of RB1 protein | 16856892 |
| D000068338 | Everolimus | [letrozole co-treated with Everolimus] results in decreased phosphorylation of and affects the activity of RB1 protein | 16033851 |
| C093323 | farnesylthiosalicylic acid | farnesylthiosalicylic acid results in decreased phosphorylation of RB1 protein | 16780807 |
| C004999 | ferulic acid | ferulic acid results in decreased phosphorylation of RB1 protein | 15486966 |
| C004999 | ferulic acid | ferulic acid results in decreased phosphorylation of RB1 protein | 15363954 |
| C028610 | flavanone | flavanone results in decreased phosphorylation of RB1 protein | 22056764 |
| D005419 | Flavonoids | Flavonoids results in increased expression of RB1 mRNA | 18035473 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene affects the phosphorylation of RB1 protein | 16448463 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene results in increased expression of and results in increased phosphorylation of RB1 protein | 15158336 |
| D015073 | 2-Acetylaminofluorene | RB1 protein affects the reaction [2-Acetylaminofluorene results in increased expression of PSMD10 protein] | 16448463 |
| D005472 | Fluorouracil | Fluorouracil affects the expression of RB1 mRNA | 15205334 |
| D005472 | Fluorouracil | Fluorouracil results in increased expression of and results in increased phosphorylation of RB1 protein | 17207318 |
| D005472 | Fluorouracil | Fluorouracil results in increased phosphorylation of RB1 protein | 9930367 |
| D005472 | Fluorouracil | RB1 protein affects the susceptibility to Fluorouracil | 17640669 |
| D005472 | Fluorouracil | RB1 protein modified form affects the susceptibility to Fluorouracil | 18383818 |
| D005472 | Fluorouracil | RB1 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] | 18678097 |
| D005472 | Fluorouracil | RB1 protein affects the susceptibility to Fluorouracil | 15064736 |
| D005485 | Flutamide | Flutamide results in decreased expression of RB1 mRNA | 24136188 |
| C065180 | fluvastatin | fluvastatin results in decreased phosphorylation of RB1 protein | 16996129 |
| C096856 | FTI 277 | [Tamoxifen co-treated with FTI 277] results in decreased phosphorylation of RB1 protein | 12866041 |
| C007789 | fucoidan | fucoidan results in decreased expression of RB1 protein | 16201850 |
| C070081 | fulvestrant | [CDK6 affects the susceptibility to fulvestrant] which affects the phosphorylation of RB1 protein | 24169358 |
| C070081 | fulvestrant | fulvestrant promotes the reaction [RB1 protein binds to CCNA2 promoter] | 21367843 |
| C070081 | fulvestrant | fulvestrant promotes the reaction [RB1 protein binds to PLK1 promoter] | 21367843 |
| C070081 | fulvestrant | fulvestrant promotes the reaction [RB1 protein binds to RNR2 promoter] | 21367843 |
| C070081 | fulvestrant | fulvestrant results in decreased phosphorylation of RB1 protein | 21367843 |
| C070081 | fulvestrant | RB1 mutant form inhibits the reaction [fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]] | 21367843 |
| C070081 | fulvestrant | RB1 mutant form inhibits the reaction [fulvestrant promotes the reaction [SIN3B protein binds to PLK1 promoter]] | 21367843 |
| C070081 | fulvestrant | RB1 mutant form inhibits the reaction [fulvestrant promotes the reaction [SIN3B protein binds to RNR2 promoter]] | 21367843 |
| C039281 | furan | furan results in decreased expression of RB1 mRNA | 26194646 |
| C038958 | gadolinium chloride | gadolinium chloride results in increased phosphorylation of RB1 protein | 19184457 |
| C037032 | galangin | galangin results in decreased phosphorylation of RB1 protein | 25450235 |
| D019833 | Genistein | Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein | 17051425 |
| D019833 | Genistein | lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein] | 17051425 |
| D005839 | Gentamicins | Gentamicins results in increased expression of RB1 mRNA | 22061828 |
| C007845 | gingerol | gingerol results in decreased phosphorylation of RB1 protein | 18058799 |
| D005897 | Glafenine | Glafenine results in decreased expression of RB1 mRNA | 24136188 |
| D005938 | Glucocorticoids | Glucocorticoids results in decreased phosphorylation of and results in decreased activity of RB1 protein | 15034294 |
| D005978 | Glutathione | Glutathione inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein] | 22927544 |
| D005978 | Glutathione | Glutathione inhibits the reaction [Levamisole results in decreased expression of RB1 protein] | 11139434 |
| D006493 | Heparin | Heparin analog results in decreased expression of and results in decreased phosphorylation of RB1 protein | 20201787 |
| D006533 | Heptachlor | Heptachlor results in decreased expression of RB1 protein | 10048758 |
| C089796 | hexabromocyclododecane | hexabromocyclododecane results in decreased expression of RB1 mRNA | 19027819 |
| C014026 | hexamethylene bisacetamide | hexamethylene bisacetamide results in decreased phosphorylation of RB1 protein | 10597302 |
| D006588 | Hexanones | Hexanones results in decreased expression of RB1 protein | 14757120 |
| D006588 | Hexanones | Hexanones results in decreased phosphorylation of RB1 protein | 14757120 |
| C070164 | homocastasterone | homocastasterone results in decreased expression of RB1 protein | 20833159 |
| C070164 | homocastasterone | homocastasterone results in decreased expression of RB1 protein modified form | 20833159 |
| D017313 | Fenretinide | Fenretinide results in increased expression of RB1 protein | 16570282 |
| C403899 | HS 1030 | HS 1030 promotes the reaction [RB1 protein binds to E2F1 protein] | 15202011 |
| C403899 | HS 1030 | HS 1030 results in decreased expression of RB1 protein | 15202011 |
| C403900 | HS 1183 | HS 1183 promotes the reaction [RB1 protein binds to E2F1 protein] | 15202011 |
| C403900 | HS 1183 | HS 1183 results in decreased expression of RB1 protein | 15202011 |
| C503536 | HS-1199 | HS-1199 promotes the reaction [RB1 protein binds to E2F1 protein] | 15202011 |
| C503536 | HS-1199 | HS-1199 results in decreased expression of RB1 protein | 15202011 |
| C479128 | HS 1200 | HS 1200 promotes the reaction [RB1 protein binds to E2F1 protein] | 15202011 |
| C479128 | HS 1200 | HS 1200 results in decreased expression of RB1 protein | 12969788|1520201 |
| C479128 | HS 1200 | HS 1200 results in decreased phosphorylation of RB1 protein | 12969788 |
| D006812 | Humic Substances | Humic Substances results in decreased expression of RB1 protein | 18683188 |
| D006812 | Humic Substances | Humic Substances results in increased phosphorylation of RB1 protein | 18683188 |
| D006812 | Humic Substances | pifithrin inhibits the reaction [Humic Substances results in decreased expression of RB1 protein] | 18683188 |
| D006835 | Hydrazones | Hydrazones results in decreased phosphorylation of RB1 protein | 22056764 |
| D006843 | Hydrocarbons, Chlorinated | "Hydrocarbons, Chlorinated results in decreased expression of RB1 protein" | 14757120 |
| D006843 | Hydrocarbons, Chlorinated | "Hydrocarbons, Chlorinated results in decreased phosphorylation of RB1 protein" | 14757120 |
| D006861 | Hydrogen Peroxide | calyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RB1 protein] | 12621062 |
| D006861 | Hydrogen Peroxide | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RB1 protein | 18951874 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide promotes the reaction [MAPT results in increased expression of RB1 protein] | 28526263 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in decreased expression of RB1 mRNA | 12419474 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in decreased phosphorylation of RB1 protein | 12621062|1524277 |
| D006861 | Hydrogen Peroxide | Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RB1 protein] | 12621062 |
| D006918 | Hydroxyurea | Hydroxyurea results in increased expression of RB1 mRNA | 27208086|2922835 |
| D006918 | Hydroxyurea | TRP53 gene mutant form inhibits the reaction [Hydroxyurea results in increased expression of RB1 mRNA] | 29228353 |
| C489023 | hypsiziprenol A9 | hypsiziprenol A9 results in decreased expression of and results in decreased phosphorylation of RB1 protein | 15246556 |
| D007052 | Ibuprofen | Ibuprofen results in decreased phosphorylation of RB1 protein | 15099639 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Albuterol results in decreased expression of RB1 protein] | 16446544 |
| D000068877 | Imatinib Mesylate | Imatinib Mesylate results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15100154 |
| C027185 | indirubin | indirubin inhibits the reaction [CDK2 protein results in increased phosphorylation of RB1 protein] | 16115123 |
| C027185 | indirubin | [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased expression of RB1 protein | 18344322 |
| C027185 | indirubin | [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased phosphorylation of RB1 protein | 18344322 |
| C027185 | indirubin | [tanshinone co-treated with indirubin] results in increased expression of RB1 protein | 18344322 |
| D007211 | Indoles | Indoles analog results in decreased phosphorylation of RB1 protein | 15149644 |
| D007213 | Indomethacin | Indomethacin results in decreased phosphorylation of RB1 protein | 18791128 |
| D007213 | Indomethacin | Indomethacin inhibits the reaction [FGF2 protein results in increased phosphorylation of RB1 protein] | 11170841 |
| C409043 | inecalcitol | inecalcitol results in decreased phosphorylation of RB1 protein | 10825140 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RB1 mRNA | 25613284 |
| C506002 | ircinin-1 | ircinin-1 results in increased phosphorylation of RB1 protein | 16163705 |
| C051890 | irinotecan | irinotecan affects the expression of RB1 protein | 15132777 |
| D015056 | 1-Methyl-3-isobutylxanthine | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein | 25559859 |
| D015056 | 1-Methyl-3-isobutylxanthine | silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein] | 25559859 |
| D017953 | Isocyanates | Isocyanates results in increased expression of RB1 protein | 20685613 |
| C036643 | isoeugenol | isoeugenol results in decreased expression of RB1 protein | 22686307 |
| C544151 | jinfukang | jinfukang results in decreased expression of RB1 mRNA | 27392435 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of RB1 mRNA | 25961927|2683047 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased phosphorylation of RB1 protein | 24796395 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound affects the phosphorylation of RB1 protein | 27440272 |
| D007649 | Ketamine | Ketamine results in decreased expression of RB1 mRNA | 20080153 |
| C074279 | KH 1060 | KH 1060 results in decreased phosphorylation of RB1 protein | 12907249 |
| C072105 | KN 93 | KN 93 results in decreased phosphorylation of RB1 protein | 15958590 |
| C477361 | LAQ824 | LAQ824 results in decreased phosphorylation of RB1 protein | 16189296 |
| D007854 | Lead | Lead affects the expression of RB1 mRNA | 28903495 |
| C017461 | lead nitrate | "4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]" | 24639330 |
| C017461 | lead nitrate | "4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 protein]" | 24639330 |
| C017461 | lead nitrate | lead nitrate promotes the reaction [RB1 protein results in increased expression of PTGS2 mRNA] | 24639330 |
| C017461 | lead nitrate | lead nitrate results in increased expression of RB1 mRNA | 24639330 |
| C017461 | lead nitrate | RB1 protein promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA] | 24639330 |
| C017461 | lead nitrate | tyrphostin AG 1478 inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA] | 24639330 |
| C017461 | lead nitrate | tyrphostin AG 1478 inhibits the reaction [lead nitrate results in increased expression of RB1 protein] | 24639330 |
| C067431 | letrozole | [letrozole co-treated with Everolimus] results in decreased phosphorylation of and affects the activity of RB1 protein | 16033851 |
| C067431 | letrozole | letrozole results in decreased phosphorylation of and affects the activity of RB1 protein | 16033851 |
| C067431 | letrozole | [Sirolimus co-treated with letrozole] results in decreased expression of RB1 protein | 20054642 |
| C067431 | letrozole | [sorafenib co-treated with letrozole] results in decreased expression of RB1 protein | 20054642 |
| C095104 | LG 100268 | LG 100268 results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15729575 |
| C095104 | LG 100268 | LG 100268 results in decreased phosphorylation of RB1 protein | 16273314 |
| D001556 | Lindane | Lindane results in decreased expression of RB1 mRNA | 17785943 |
| C002385 | linsidomine | linsidomine results in decreased phosphorylation of RB1 protein | 12600834 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in decreased expression of RB1 mRNA | 12057914 |
| D018021 | Lithium Chloride | Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein] | 22820424 |
| D018021 | Lithium Chloride | Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]] | 15845746 |
| C115354 | lonafarnib | lonafarnib results in decreased phosphorylation of and results in decreased activity of RB1 protein | 12673674 |
| D061466 | Lopinavir | Lopinavir affects the phosphorylation of RB1 protein | 20596751 |
| D008148 | Lovastatin | Lovastatin results in decreased phosphorylation of RB1 protein | 10502407|1511840 |
| D008148 | Lovastatin | Lovastatin results in decreased phosphorylation of RB1 protein | 9848777 |
| C015329 | lycopene | lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein] | 17051425 |
| C015329 | lycopene | lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] | 16565789 |
| C015329 | lycopene | lycopene results in decreased phosphorylation of RB1 protein | 17337101 |
| C009818 | lysocellin | lysocellin results in decreased phosphorylation of RB1 protein | 16525630 |
| D009637 | Masoprocol | Masoprocol results in decreased phosphorylation of RB1 protein | 18164318 |
| C051883 | maxacalcitol | maxacalcitol results in decreased phosphorylation of RB1 protein | 16039115 |
| D008701 | Methapyrilene | Methapyrilene results in decreased expression of RB1 mRNA | 15890375 |
| D008727 | Methotrexate | Methotrexate inhibits the reaction [RB1 protein binds to E2F1 protein] | 22484375 |
| D008727 | Methotrexate | Methotrexate results in increased phosphorylation of RB1 protein | 22484375 |
| D008727 | Methotrexate | RB1 gene affects the susceptibility to Methotrexate | 14679136 |
| D008727 | Methotrexate | RB1 protein affects the susceptibility to Methotrexate | 12972956 |
| D008727 | Methotrexate | RB1 protein results in increased susceptibility to Methotrexate | 14534726 |
| D008727 | Methotrexate | Methotrexate results in increased phosphorylation of RB1 protein | 22484375 |
| C013598 | methoxyacetic acid | "6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [methoxyacetic acid results in increased phosphorylation of RB1 protein]" | 21573189 |
| C013598 | methoxyacetic acid | methoxyacetic acid results in increased phosphorylation of RB1 protein | 21573189 |
| D008730 | Methoxsalen | Methoxsalen inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] | 15157999 |
| C005223 | methyleugenol | methyleugenol results in decreased expression of RB1 mRNA | 26011634 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of RB1 mRNA | 28526320 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in increased expression of RB1 mRNA | 23649840 |
| D008770 | Methylnitrosourea | Methylnitrosourea results in increased phosphorylation of RB1 protein | 15581186 |
| D015655 | 1-Methyl-4-phenylpyridinium | 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RB1 protein | 15247282 |
| C008493 | methylselenic acid | methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein] | 17847021 |
| C008493 | methylselenic acid | methylselenic acid results in decreased phosphorylation of and results in increased expression of RB1 protein | 17847021 |
| D015735 | Mifepristone | Mifepristone results in increased activity of RB1 protein | 15297425 |
| D016685 | Mitomycin | Mitomycin results in decreased expression of RB1 protein modified form | 15617745 |
| C060893 | MK-886 | MK-886 inhibits the reaction [Nicotine results in increased expression of RB1 protein modified form] | 20061081 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in decreased expression of RB1 mRNA | 22108045 |
| C035359 | monorden | monorden affects the phosphorylation of RB1 protein | 21880723 |
| C437683 | motexafin gadolinium | motexafin gadolinium results in decreased expression of RB1 mRNA | 16357179 |
| C437683 | motexafin gadolinium | [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA | 16357179 |
| C523799 | MRK 003 | "2-bromo-12,13-dihydro-5-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione promotes the reaction [MRK 003 results in decreased phosphorylation of and results in increased activity of RB1 protein]" | 19318552 |
| C523799 | MRK 003 | MRK 003 results in decreased expression of RB1 mRNA | 21169257 |
| C523799 | MRK 003 | MRK 003 results in decreased phosphorylation of and results in increased activity of RB1 protein | 19318552 |
| C523799 | MRK 003 | [MRK 003 results in increased expression of CDKN2D protein] which results in decreased phosphorylation of and results in increased activity of RB1 protein | 19318552 |
| C523799 | MRK 003 | NOTCH1 protein modified form inhibits the reaction [MRK 003 results in decreased phosphorylation of and results in increased activity of RB1 protein] | 19318552 |
| D009151 | Mustard Gas | Mustard Gas results in increased phosphorylation of RB1 protein | 19845377 |
| D009151 | Mustard Gas | Mustard Gas results in increased expression of RB1 mRNA | 15674843 |
| C451426 | N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide | "N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of RB1 mRNA" | 25461557 |
| C451426 | N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide | "[systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] affects the expression of RB1 mRNA" | 25461557 |
| C562255 | N-(2-(4-hydroxyphenyl)ethyl)-2-(2,5-dimethoxyphenyl)-3-(3-methoxy-4-hydroxyphenyl)acrylamide | "N-(2-(4-hydroxyphenyl)ethyl)-2-(2,5-dimethoxyphenyl)-3-(3-methoxy-4-hydroxyphenyl)acrylamide results in decreased phosphorylation of RB1 protein" | 21835169 |
| C439829 | N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide | "N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide results in decreased phosphorylation of RB1 protein" | 15269140 |
| C550356 | N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | "(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol affects the reaction [N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide affects the phosphorylation of and affects the expression of RB1 protein]" | 24444656 |
| C550356 | N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | "N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide affects the phosphorylation of and affects the expression of RB1 protein" | 24444656 |
| C017096 | n-butoxyethanol | n-butoxyethanol results in increased expression of RB1 mRNA | 19812364 |
| C051752 | nefazodone | nefazodone results in decreased expression of RB1 mRNA | 24136188 |
| D009532 | Nickel | Nickel results in decreased expression of RB1 mRNA | 23195993 |
| C022838 | nickel chloride | nickel chloride results in decreased expression of RB1 protein | 21837363 |
| D009538 | Nicotine | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in increased phosphorylation of RB1 protein] | 18805435 |
| D009538 | Nicotine | Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | 16862215 |
| D009538 | Nicotine | ARRB1 protein affects the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | 16862215 |
| D009538 | Nicotine | Bungarotoxins inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | 16862215 |
| D009538 | Nicotine | CHRNA7 protein affects the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | 16862215 |
| D009538 | Nicotine | MK-886 inhibits the reaction [Nicotine results in increased expression of RB1 protein modified form] | 20061081 |
| D009538 | Nicotine | Nicotine inhibits the reaction [RB1 protein binds to BIRC5 promoter] | 16601104 |
| D009538 | Nicotine | Nicotine inhibits the reaction [RB1 protein binds to CDC25A promoter] | 16862215 |
| D009538 | Nicotine | Nicotine inhibits the reaction [RB1 protein binds to CDC6 promoter] | 16862215 |
| D009538 | Nicotine | Nicotine promotes the reaction [RB1 protein binds to RAF1 protein] | 16862215 |
| D009538 | Nicotine | Nicotine results in decreased expression of RB1 protein | 16011614 |
| D009538 | Nicotine | Nicotine results in increased expression of RB1 protein modified form | 20061081 |
| D009538 | Nicotine | Nicotine results in increased phosphorylation of RB1 protein | 16862215|1844848 |
| D009538 | Nicotine | SRC protein affects the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | 16862215 |
| D009538 | Nicotine | Nicotine results in increased phosphorylation of RB1 protein | 15574422 |
| C012655 | nimesulide | nimesulide results in decreased expression of RB1 mRNA | 24136188 |
| D009585 | Nitrogen Dioxide | Nitrogen Dioxide results in decreased phosphorylation of RB1 protein | 12600834 |
| C044387 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | "N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA" | 18778698 |
| C044387 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | "TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA]" | 18778698 |
| C404397 | NSC 680410 | NSC 680410 affects the cleavage of RB1 protein | 14647418 |
| C404397 | NSC 680410 | NSC 680410 results in decreased phosphorylation of RB1 protein | 14647418 |
| C466913 | NU2058 | NU2058 results in decreased phosphorylation of RB1 protein | 17599054 |
| C066515 | O-(chloroacetylcarbamoyl)fumagillol | O-(chloroacetylcarbamoyl)fumagillol results in decreased phosphorylation of RB1 protein | 15276080 |
| C025589 | ochratoxin A | ochratoxin A affects the expression of and affects the phosphorylation of RB1 protein | 28286205 |
| D019301 | Oleic Acid | Oleic Acid results in decreased phosphorylation of RB1 protein | 16027227 |
| D019319 | Okadaic Acid | Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RB1 protein] | 12621062 |
| D009840 | Oligomycins | Oligomycins promotes the reaction [RB1 protein binds to E2F1 protein] | 15925326 |
| D009840 | Oligomycins | Oligomycins results in decreased phosphorylation of RB1 protein | 15925326 |
| C090046 | olomoucine | olomoucine results in increased expression of RB1 protein | 14653808 |
| C090046 | olomoucine | olomoucine results in increased expression of RB1 mRNA | 14653808 |
| C090046 | olomoucine | olomoucine results in increased expression of RB1 protein | 14653808 |
| C000594117 | ON123300 | ON123300 results in decreased phosphorylation of RB1 protein | 26174628|2687384 |
| C055122 | orlistat | orlistat results in decreased phosphorylation of RB1 protein | 15138278 |
| C030110 | oxaliplatin | oxaliplatin results in decreased phosphorylation of RB1 protein | 15204521|1622740 |
| C030110 | oxaliplatin | oxaliplatin results in increased phosphorylation of RB1 protein | 15204521 |
| D010100 | Oxygen | Oxygen deficiency results in increased expression of RB1 mRNA | 22629407 |
| D010100 | Oxygen | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of RB1 mRNA] | 22629407 |
| D017239 | Paclitaxel | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Paclitaxel results in increased phosphorylation of RB1 protein] | 15138593 |
| D017239 | Paclitaxel | Paclitaxel results in increased phosphorylation of RB1 protein | 15138593 |
| C500026 | palbociclib | BMS 754807 promotes the reaction [palbociclib results in decreased phosphorylation of RB1 protein] | 24986516 |
| C500026 | palbociclib | E2F2 protein inhibits the reaction [palbociclib results in decreased phosphorylation of RB1 protein] | 20473330 |
| C500026 | palbociclib | palbociclib affects the phosphorylation of RB1 protein | 21880723 |
| C500026 | palbociclib | palbociclib affects the reaction [RB1 mutant form results in increased expression of RBL2 protein] | 20473330 |
| C500026 | palbociclib | palbociclib inhibits the reaction [[CDK6 protein binds to CCND3 protein] which results in increased phosphorylation of RB1 protein] | 22094256 |
| C500026 | palbociclib | palbociclib inhibits the reaction [[PDGFB protein binds to PDGFB protein] inhibits the reaction [RB1 protein binds to SP1 protein]] | 21880723 |
| C500026 | palbociclib | palbociclib promotes the reaction [RB1 protein binds to CCNA2 promoter] | 21367843 |
| C500026 | palbociclib | palbociclib promotes the reaction [RB1 protein binds to SP1 protein] | 21880723 |
| C500026 | palbociclib | palbociclib results in decreased phosphorylation of and results in decreased expression of RB1 protein | 20473330|2127824 |
| C500026 | palbociclib | palbociclib results in decreased phosphorylation of RB1 protein | 15542782|1669096 |
| C500026 | palbociclib | palbociclib results in increased phosphorylation of RB1 protein | 23138228 |
| C500026 | palbociclib | RB1 gene mutant form results in decreased susceptibility to palbociclib | 21278246 |
| C500026 | palbociclib | RB1 mutant form results in decreased susceptibility to palbociclib | 24986516 |
| C500026 | palbociclib | RB1 protein affects the reaction palbociclib | 25221644 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]] | 22751436 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of CCNA2 protein]] | 22751436 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of E2F1 protein]] | 22751436 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of TOP2A protein]] | 22751436 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib inhibits the reaction [RBL1 protein binds to CCNA2 promoter]] | 20100483 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib inhibits the reaction [RBL1 protein binds to PLK1 promoter]] | 20100483 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib inhibits the reaction [RBL1 protein binds to RNR2 promoter]] | 20100483 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]] | 20100483 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib results in decreased expression of CCNA2 protein] | 20473330 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib results in decreased expression of MCM7 protein] | 20473330 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib results in decreased expression of RBL1 protein] | 20100483 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib results in decreased phosphorylation of H2AFX protein] | 22751436 |
| C500026 | palbociclib | RB1 protein affects the reaction [palbociclib results in decreased phosphorylation of RB1 protein] | 22761470 |
| C500026 | palbociclib | RB1 protein affects the susceptibility to palbociclib | 20354191|2047333 |
| C500026 | palbociclib | RB1 protein results in increased susceptibility to palbociclib | 21278246|2370865 |
| C500026 | palbociclib | [CDKN2A gene mutant form results in increased susceptibility to palbociclib] which results in decreased phosphorylation of RB1 protein | 24098593 |
| C500026 | palbociclib | palbociclib results in decreased phosphorylation of RB1 protein | 22508966|2389805 |
| C055778 | panaxydol | panaxydol results in increased expression of RB1 protein | 19450571 |
| C055778 | panaxydol | panaxydol results in increased expression of RB1 protein modified form | 19450571 |
| D052638 | Particulate Matter | Particulate Matter results in increased expression of RB1 protein | 20850422 |
| D052638 | Particulate Matter | Particulate Matter results in increased expression of RB1 protein modified form | 20850422 |
| D010416 | Pentachlorophenol | Pentachlorophenol results in increased phosphorylation of RB1 protein | 19442831 |
| D010424 | Pentobarbital | Pentobarbital results in decreased expression of RB1 protein modified form | 19346066 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in decreased expression of RB1 protein | 26879310 |
| D037342 | Pertussis Toxin | Pertussis Toxin inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of RB1 protein] | 21813366 |
| D010634 | Phenobarbital | Phenobarbital results in decreased expression of RB1 mRNA | 16940010 |
| D010656 | Phenylephrine | Phenylephrine affects the phosphorylation of RB1 protein | 18084315 |
| D010656 | Phenylephrine | Phenylephrine results in increased expression of RB1 protein | 15603588 |
| C003117 | phosalone | Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA] | 27965107 |
| C003117 | phosalone | Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] | 27965107 |
| C003117 | phosalone | phosalone results in increased expression of RB1 mRNA | 27965107 |
| C003117 | phosalone | phosalone results in increased expression of RB1 protein | 27965107 |
| D010833 | Phytic Acid | Phytic Acid results in decreased phosphorylation of RB1 protein | 15868430 |
| C121565 | pifithrin | pifithrin inhibits the reaction [Humic Substances results in decreased expression of RB1 protein] | 18683188 |
| C049032 | pinosylvin | pinosylvin results in decreased expression of RB1 protein | 23333577 |
| C060836 | pioglitazone | pioglitazone results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15729575 |
| C498077 | piperlonguminine | piperlonguminine results in decreased phosphorylation of RB1 protein | 29109039 |
| D010882 | Piperonyl Butoxide | Piperonyl Butoxide results in decreased expression of RB1 mRNA | 15890375 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of RB1 mRNA | 15890375 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of RB1 mRNA | 16940010 |
| D010894 | Piroxicam | Piroxicam results in decreased expression of RB1 mRNA | 21858171 |
| D010936 | Plant Extracts | Plant Extracts results in decreased phosphorylation of RB1 protein | 15327971 |
| D011084 | Polycyclic Aromatic Hydrocarbons | Polycyclic Aromatic Hydrocarbons results in decreased expression of RB1 mRNA | 16002475 |
| D011134 | Polysaccharides | Polysaccharides results in increased expression of RB1 mRNA | 18753065 |
| D011134 | Polysaccharides | Polysaccharides results in increased expression of RB1 protein | 18753065 |
| D011241 | Prednisone | Prednisone results in decreased phosphorylation of and results in decreased activity of RB1 protein | 15034294 |
| C017674 | procyanidin | procyanidin results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15827326 |
| D011374 | Progesterone | Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]] | 15845746 |
| D011374 | Progesterone | Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein] | 15845746 |
| D011398 | Promethazine | Promethazine results in decreased expression of RB1 mRNA | 26011634 |
| D011441 | Propylthiouracil | Propylthiouracil results in decreased expression of RB1 mRNA | 24780913 |
| C107773 | pterostilbene | pterostilbene results in decreased expression of RB1 protein | 20398797 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of RB1 mRNA] | 14729647 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| C009131 | pyrimidin-2-one beta-ribofuranoside | pyrimidin-2-one beta-ribofuranoside results in decreased expression of RB1 protein modified form | 23320119 |
| D011794 | Quercetin | [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein | 25070040 |
| D011794 | Quercetin | Quercetin affects the expression of RB1 protein modified form | 14767529 |
| D011794 | Quercetin | Quercetin inhibits the reaction [IL6 protein results in increased phosphorylation of RB1 protein] | 22394507 |
| D011794 | Quercetin | Quercetin results in decreased phosphorylation of RB1 protein | 16049707|1900955 |
| D011794 | Quercetin | Quercetin results in increased expression of RB1 mRNA | 14715546 |
| D011794 | Quercetin | [Butyric Acid co-treated with Quercetin] results in decreased phosphorylation of RB1 protein | 25070040 |
| D020849 | Raloxifene Hydrochloride | Raloxifene Hydrochloride results in decreased expression of RB1 mRNA | 19429434 |
| C059514 | resveratrol | resveratrol inhibits the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein] | 23881456 |
| C059514 | resveratrol | resveratrol results in decreased phosphorylation of RB1 protein | 11481417|1676196 |
| C059514 | resveratrol | [temozolomide co-treated with resveratrol] results in increased phosphorylation of RB1 protein | 23522185 |
| C059514 | resveratrol | resveratrol results in decreased phosphorylation of RB1 protein | 18567737 |
| C059514 | resveratrol | resveratrol affects the expression of RB1 mRNA | 16369916 |
| C059514 | resveratrol | resveratrol affects the expression of RB1 protein | 16369916 |
| C059514 | resveratrol | resveratrol results in decreased phosphorylation of RB1 protein | 23525482 |
| C059514 | resveratrol | resveratrol results in decreased expression of RB1 protein modified form | 22104698 |
| C540615 | retigeric acid B | retigeric acid B results in increased expression of RB1 protein modified form | 20692244 |
| D012176 | Retinoids | [Am 580 co-treated with Retinoids] results in decreased phosphorylation of RB1 protein | 15383624 |
| D012176 | Retinoids | [tazarotene co-treated with Retinoids] results in decreased phosphorylation of RB1 protein | 15383624 |
| D019438 | Ritonavir | Ritonavir results in decreased phosphorylation of RB1 protein | 16551874|1938611 |
| D019438 | Ritonavir | Ritonavir results in increased expression of RB1 mRNA | 19386116 |
| C084904 | Ro 41-5253 | Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]] | 12421932 |
| C087123 | romidepsin | romidepsin results in decreased phosphorylation of RB1 protein | 15014036|1584972 |
| C104586 | roscovitine | roscovitine results in increased expression of RB1 protein | 14653808 |
| C104586 | roscovitine | roscovitine results in decreased phosphorylation of and results in decreased expression of RB1 protein | 21217777 |
| C104586 | roscovitine | roscovitine results in decreased phosphorylation of RB1 protein | 15741232 |
| C104586 | roscovitine | roscovitine results in increased expression of RB1 mRNA | 14653808 |
| C104586 | roscovitine | roscovitine results in increased expression of RB1 protein | 14653808 |
| C089730 | rosiglitazone | rosiglitazone results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15729575 |
| C089730 | rosiglitazone | rosiglitazone results in decreased phosphorylation of RB1 protein | 21376716 |
| C089730 | rosiglitazone | rosiglitazone results in increased phosphorylation of RB1 protein | 20210794 |
| C085746 | rottlerin | rottlerin results in decreased phosphorylation of RB1 protein | 15949478 |
| C085746 | rottlerin | rottlerin results in decreased phosphorylation of RB1 protein | 15949478 |
| C039961 | S-(1,2-dichlorovinyl)cysteine | "S-(1,2-dichlorovinyl)cysteine results in increased phosphorylation of RB1 protein" | 16495211 |
| C513635 | S-2-pentyl-4-pentynoic hydroxamic acid | S-2-pentyl-4-pentynoic hydroxamic acid results in increased expression of RB1 mRNA | 21427059 |
| C093642 | SB 203580 | SB 203580 inhibits the reaction [FGF2 protein results in increased phosphorylation of RB1 protein] | 15249425 |
| C078903 | seocalcitol | seocalcitol results in decreased phosphorylation of RB1 protein | 12907249 |
| C440975 | silybin | silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein] | 25559859 |
| D019821 | Simvastatin | Simvastatin results in decreased phosphorylation of RB1 protein | 17928568 |
| D019821 | Simvastatin | Simvastatin results in decreased phosphorylation of RB1 protein | 18804536 |
| D020123 | Sirolimus | [Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [IL2 protein results in increased phosphorylation of RB1 protein] | 15778701 |
| D020123 | Sirolimus | [Sirolimus co-treated with letrozole] results in decreased expression of RB1 protein | 20054642 |
| D020123 | Sirolimus | [Sirolimus co-treated with TGFB1 protein] results in decreased phosphorylation of RB1 protein | 14979923 |
| D020123 | Sirolimus | Sirolimus inhibits the reaction [IL2 protein results in increased phosphorylation of RB1 protein] | 10373522 |
| D020123 | Sirolimus | Sirolimus results in decreased phosphorylation of RB1 protein | 12393642|1256587 |
| D020123 | Sirolimus | [tanespimycin co-treated with Sirolimus] results in decreased phosphorylation of RB1 protein | 17121904 |
| D020123 | Sirolimus | [TGFB1 protein co-treated with Sirolimus] results in decreased phosphorylation of RB1 protein | 17700525 |
| D020123 | Sirolimus | [Sirolimus co-treated with TGFB1 protein] results in decreased phosphorylation of RB1 protein | 14979923 |
| D020123 | Sirolimus | Sirolimus inhibits the reaction [KITL protein results in increased phosphorylation of RB1 protein] | 10849422 |
| D020123 | Sirolimus | [TGFB1 protein co-treated with Sirolimus] results in decreased phosphorylation of RB1 protein | 12417722 |
| D020123 | Sirolimus | [TGFB1 protein co-treated with Sirolimus] results in decreased phosphorylation of RB1 protein | 12417722 |
| D020123 | Sirolimus | Sirolimus results in decreased phosphorylation of RB1 protein | 7532117 |
| C439060 | sirtinol | sirtinol promotes the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein] | 23881456 |
| C017947 | sodium arsenite | JUN protein promotes the reaction [sodium arsenite results in increased phosphorylation of RB1 protein] | 21726611 |
| C017947 | sodium arsenite | MAPK8 protein promotes the reaction [sodium arsenite results in increased phosphorylation of RB1 protein] | 21726611 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of RB1 mRNA | 17879257 |
| C017947 | sodium arsenite | sodium arsenite results in increased phosphorylation of RB1 protein | 21726611 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of RB1 mRNA | 19822182 |
| C017947 | sodium arsenite | sodium arsenite results in increased phosphorylation of RB1 protein | 11807808 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of RB1 mRNA | 11241755 |
| C016104 | sodium bichromate | sodium bichromate results in decreased expression of RB1 mRNA | 25993096 |
| C471405 | sorafenib | [sorafenib co-treated with letrozole] results in decreased expression of RB1 protein | 20054642 |
| C471405 | sorafenib | sorafenib results in decreased expression of RB1 protein | 17909054|1963342 |
| C471405 | sorafenib | sorafenib results in decreased phosphorylation of RB1 protein | 17909054 |
| C016766 | sulforafan | sulforafan results in increased phosphorylation of RB1 protein | 15231455 |
| D013458 | Sulfur Dioxide | [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA | 19408242 |
| D013458 | Sulfur Dioxide | [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 protein | 19408242 |
| D013458 | Sulfur Dioxide | Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 mRNA] | 20064080 |
| D013458 | Sulfur Dioxide | Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 protein] | 20064080 |
| D013458 | Sulfur Dioxide | Sulfur Dioxide results in decreased expression of RB1 mRNA | 19408242|1943469 |
| D013458 | Sulfur Dioxide | Sulfur Dioxide results in decreased expression of RB1 protein | 19434695|2006408 |
| D013458 | Sulfur Dioxide | Sulfur Dioxide results in increased expression of RB1 protein | 19408242 |
| D013467 | Sulindac | Sulindac results in decreased expression of RB1 protein | 16488075 |
| C025462 | sulindac sulfide | sulindac sulfide affects the activity of RB1 protein | 15694660 |
| C446685 | systhane | "[systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] affects the expression of RB1 mRNA" | 25461557 |
| C446685 | systhane | systhane results in increased expression of RB1 mRNA | 25461557 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of RB1 mRNA | 17403546 |
| C112689 | TAC 101 | TAC 101 results in increased phosphorylation of RB1 protein | 10225456 |
| D013629 | Tamoxifen | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tamoxifen results in decreased phosphorylation of RB1 protein] | 14645110 |
| D013629 | Tamoxifen | [Tamoxifen co-treated with FTI 277] results in decreased phosphorylation of RB1 protein | 12866041 |
| D013629 | Tamoxifen | Tamoxifen results in decreased phosphorylation of RB1 protein | 14645110 |
| D013629 | Tamoxifen | Tamoxifen results in increased phosphorylation of RB1 protein | 15642790 |
| D013629 | Tamoxifen | Tamoxifen results in decreased expression of RB1 protein | 17343880 |
| D013629 | Tamoxifen | [Tamoxifen results in increased expression of MIR106A mRNA] which results in decreased expression of RB1 protein | 17343880 |
| C112765 | tanespimycin | [tanespimycin co-treated with Sirolimus] results in decreased phosphorylation of RB1 protein | 17121904 |
| C112765 | tanespimycin | tanespimycin results in decreased phosphorylation of RB1 protein | 17121904 |
| C021751 | tanshinone | [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased expression of RB1 protein | 18344322 |
| C021751 | tanshinone | [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased phosphorylation of RB1 protein | 18344322 |
| C021751 | tanshinone | [tanshinone co-treated with indirubin] results in increased expression of RB1 protein | 18344322 |
| C021751 | tanshinone | [tanshinone co-treated with tetraarsenic tetrasulfide] results in increased expression of RB1 protein | 18344322 |
| C021751 | tanshinone | tanshinone results in increased expression of RB1 protein | 18344322 |
| C031655 | tauroursodeoxycholic acid | tauroursodeoxycholic acid results in decreased expression of RB1 protein | 15255934 |
| C086827 | tazarotene | [tazarotene co-treated with Retinoids] results in decreased phosphorylation of RB1 protein | 15383624 |
| C047246 | temozolomide | [temozolomide co-treated with resveratrol] results in increased phosphorylation of RB1 protein | 23522185 |
| C401859 | temsirolimus | temsirolimus promotes the reaction [2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol results in decreased phosphorylation of RB1 protein] | 16954435 |
| C401859 | temsirolimus | temsirolimus results in decreased expression of RB1 protein | 16954435 |
| C011363 | terephthalic acid | terephthalic acid results in increased expression of RB1 protein | 16896691 |
| C011363 | terephthalic acid | terephthalic acid results in increased phosphorylation of RB1 protein | 16896691 |
| C527525 | teriflunomide | teriflunomide inhibits the reaction [[CpG-ODN DSP30 co-treated with IL2 protein] results in increased expression of RB1 protein] | 17805332 |
| D013729 | Terpenes | Terpenes affects the phosphorylation of RB1 protein | 18281026 |
| C534735 | tetraarsenic tetrasulfide | [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased expression of RB1 protein | 18344322 |
| C534735 | tetraarsenic tetrasulfide | [indirubin co-treated with tanshinone co-treated with tetraarsenic tetrasulfide] results in increased phosphorylation of RB1 protein | 18344322 |
| C534735 | tetraarsenic tetrasulfide | [tanshinone co-treated with tetraarsenic tetrasulfide] results in increased expression of RB1 protein | 18344322 |
| D013749 | Tetrachlorodibenzodioxin | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] | 15157999 |
| D013749 | Tetrachlorodibenzodioxin | Methoxsalen inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] | 15157999 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin inhibits the reaction [[AHR protein binds to CDK4 protein binds to CCND1 protein] which results in increased phosphorylation of RB1 protein] | 19917880 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein] | 9705214 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein | 15157999|1532224 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of RB1 mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | "[Tetrachlorodibenzodioxin co-treated with 1,4-bis(2-(3,5-dichloropyridyloxy))benzene] results in increased phosphorylation of RB1 protein" | 20637255 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RB1 mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein | 24013123 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of RB1 mRNA | 12167310 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of RB1 mRNA | 21215274 |
| D013755 | Tetradecanoylphorbol Acetate | "4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]" | 12421932 |
| D013755 | Tetradecanoylphorbol Acetate | IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein] | 12421932 |
| D013755 | Tetradecanoylphorbol Acetate | Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]] | 12421932 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in decreased phosphorylation of RB1 protein | 15978937 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased expression of RB1 protein modified form | 9348195 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein | 12421932|8927716 |
| D013755 | Tetradecanoylphorbol Acetate | Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein] | 12421932 |
| D013755 | Tetradecanoylphorbol Acetate | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RB1 mRNA | 16979875 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RB1 mRNA | 25613284 |
| D007978 | Levamisole | Acetylcysteine inhibits the reaction [Levamisole results in decreased expression of RB1 protein] | 11139434 |
| D007978 | Levamisole | Glutathione inhibits the reaction [Levamisole results in decreased expression of RB1 protein] | 11139434 |
| D007978 | Levamisole | Levamisole results in decreased expression of RB1 protein | 11139434 |
| D013806 | Theophylline | [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein] | 9454737 |
| D013806 | Theophylline | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RB1 protein | 18951874 |
| D013853 | Thioacetamide | Thioacetamide results in increased expression of RB1 mRNA | 17997003 |
| D013853 | Thioacetamide | Thioacetamide results in decreased expression of RB1 mRNA | 16337175|2601163 |
| D013853 | Thioacetamide | Thioacetamide results in increased phosphorylation of and results in decreased activity of RB1 protein | 15953624 |
| D013876 | Thiophenes | Thiophenes analog promotes the reaction [Tretinoin results in decreased phosphorylation of RB1 protein] | 16140954 |
| D013893 | Thiram | Thiram results in decreased expression of RB1 mRNA | 20530235 |
| C475928 | THRX 165724 | THRX 165724 results in decreased phosphorylation of RB1 protein | 17537993 |
| D024505 | Tocopherols | Tocopherols results in decreased phosphorylation of RB1 protein | 12504091 |
| D014044 | Tolbutamide | Tolbutamide results in decreased phosphorylation of RB1 protein | 16718685 |
| D014050 | Toluene | Toluene results in increased phosphorylation of RB1 protein | 9118908 |
| D014112 | Toxaphene | Toxaphene results in decreased expression of RB1 protein | 10048758 |
| C560077 | trametinib | trametinib results in decreased phosphorylation of RB1 protein | 22733540 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of RB1 mRNA | 20530235 |
| D014212 | Tretinoin | CSF1R promotes the reaction [Tretinoin results in decreased phosphorylation of RB1 protein] | 9158000 |
| D014212 | Tretinoin | PTK2 protein inhibits the reaction [Tretinoin promotes the reaction [CEBPA protein binds to RB1 protein]] | 16226872 |
| D014212 | Tretinoin | Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]] | 12421932 |
| D014212 | Tretinoin | Thiophenes analog promotes the reaction [Tretinoin results in decreased phosphorylation of RB1 protein] | 16140954 |
| D014212 | Tretinoin | [Tretinoin co-treated with TGFB1 protein] results in decreased phosphorylation of RB1 protein | 16242776 |
| D014212 | Tretinoin | Tretinoin inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] | 16565789 |
| D014212 | Tretinoin | Tretinoin inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased phosphorylation of RB1 protein] | 11348869 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [CEBPA protein binds to RB1 protein] | 16226872 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [CPG-oligonucleotide results in increased phosphorylation of RB1 protein] | 17209053 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein] | 12421932 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of RB1 protein | 12042460 |
| D014212 | Tretinoin | Tretinoin results in decreased phosphorylation of RB1 protein | 11519864|1512632 |
| D014212 | Tretinoin | Tretinoin results in increased activity of RB1 protein | 15194426 |
| D014212 | Tretinoin | Tretinoin results in increased expression of and results in decreased phosphorylation of RB1 protein | 15194426 |
| D014212 | Tretinoin | Tretinoin results in increased expression of RB1 mRNA | 15194426|1577063 |
| D014212 | Tretinoin | Tretinoin results in increased expression of RB1 protein | 15194426|1577063 |
| D014212 | Tretinoin | Tretinoin results in increased phosphorylation of RB1 protein | 16920920 |
| D014212 | Tretinoin | Tretinoin inhibits the reaction [RB1 protein binds to RETN promoter] | 15047602 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of RB1 protein | 15949692 |
| D014212 | Tretinoin | Tretinoin results in decreased phosphorylation of RB1 protein | 18425745 |
| D014212 | Tretinoin | Tretinoin results in increased phosphorylation of RB1 protein | 15949692|1684054 |
| C012589 | trichostatin A | [trichostatin A affects the expression of DNMT3B protein] which affects the expression of RB1 mRNA | 18544619 |
| C012589 | trichostatin A | trichostatin A results in decreased activity of RB1 protein | 15494029 |
| C012589 | trichostatin A | trichostatin A results in decreased phosphorylation of and results in increased expression of RB1 protein | 15179185 |
| C012589 | trichostatin A | trichostatin A results in increased expression of RB1 mRNA | 24935251 |
| C057693 | troglitazone | Aspirin inhibits the reaction [troglitazone results in decreased expression of RB1 protein modified form] | 19908241 |
| C057693 | troglitazone | Aspirin promotes the reaction [troglitazone results in increased expression of RB1 protein] | 19908241 |
| C057693 | troglitazone | troglitazone inhibits the reaction [Aspirin results in decreased expression of RB1 protein modified form] | 19908241 |
| C057693 | troglitazone | troglitazone promotes the reaction [Aspirin results in increased expression of RB1 protein] | 19908241 |
| C057693 | troglitazone | troglitazone results in decreased expression of RB1 protein modified form | 11834241|1990824 |
| C057693 | troglitazone | troglitazone results in decreased phosphorylation of and results in decreased expression of RB1 protein | 15729575 |
| C057693 | troglitazone | troglitazone results in decreased phosphorylation of RB1 protein | 12595159 |
| C057693 | troglitazone | troglitazone results in increased expression of RB1 protein | 19908241 |
| C057693 | troglitazone | troglitazone results in increased phosphorylation of RB1 protein | 11741176 |
| C057693 | troglitazone | troglitazone results in decreased expression of RB1 mRNA | 28973697 |
| C080163 | trovafloxacin | trovafloxacin results in decreased expression of RB1 mRNA | 24136188 |
| D014415 | Tunicamycin | HSPA5 protein affects the reaction [[Tunicamycin co-treated with HRAS protein] results in increased phosphorylation of RB1 protein] | 24898257 |
| D014415 | Tunicamycin | [Tunicamycin co-treated with HRAS protein] results in increased phosphorylation of RB1 protein | 24898257 |
| C101044 | tyrphostin AG 1478 | tyrphostin AG 1478 inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA] | 24639330 |
| C101044 | tyrphostin AG 1478 | tyrphostin AG 1478 inhibits the reaction [lead nitrate results in increased expression of RB1 protein] | 24639330 |
| C113580 | U 0126 | U 0126 results in decreased phosphorylation of RB1 protein | 15547725|1593030 |
| C000602704 | UF010 compound | UF010 compound results in increased activity of RB1 protein | 25699604 |
| D014520 | Urethane | Urethane results in decreased expression of RB1 mRNA | 12117781 |
| D014580 | Ursodeoxycholic Acid | Ursodeoxycholic Acid results in decreased expression of RB1 protein modified form | 17461466 |
| C406224 | valdecoxib | valdecoxib results in decreased expression of RB1 mRNA | 24136188 |
| D014635 | Valproic Acid | Valproic Acid results in decreased methylation of RB1 gene | 29154799 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of RB1 mRNA | 24935251 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of RB1 mRNA | 20546886|2142705 |
| D014638 | Vanadates | AKT1 protein affects the reaction [Vanadates inhibits the reaction [chromium hexavalent ion affects the localization of RB1 protein]] | 19377290 |
| D014638 | Vanadates | Vanadates inhibits the reaction [chromium hexavalent ion affects the localization of RB1 protein] | 19377290 |
| D014638 | Vanadates | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vanadates results in increased phosphorylation of RB1 protein] | 14971663 |
| D014638 | Vanadates | Vanadates results in increased phosphorylation of RB1 protein | 14971663 |
| D014638 | Vanadates | wortmannin inhibits the reaction [Vanadates results in increased phosphorylation of RB1 protein] | 14971663 |
| C017963 | vinyl carbamate | vinyl carbamate results in decreased expression of RB1 mRNA | 17849452 |
| D002762 | Cholecalciferol | Cholecalciferol results in increased expression of RB1 protein | 18628207 |
| D002762 | Cholecalciferol | RAF1 mutant form inhibits the reaction [Cholecalciferol results in increased expression of RB1 protein] | 18628207 |
| C024534 | vitamin k5 | vitamin k5 results in increased expression of RB1 mRNA | 16010434 |
| D024482 | Vitamin K 2 | Vitamin K 2 results in increased expression of RB1 mRNA | 16010434 |
| D024483 | Vitamin K 3 | Vitamin K 3 results in increased expression of RB1 mRNA | 16010434 |
| C111237 | vorinostat | [Bortezomib co-treated with vorinostat] results in increased degradation of RB1 protein | 12893773 |
| C111237 | vorinostat | vorinostat results in decreased phosphorylation of and results in increased cleavage of RB1 protein | 10597302 |
| C111237 | vorinostat | vorinostat results in decreased phosphorylation of RB1 protein | 14707268 |
| C111237 | vorinostat | vorinostat results in increased expression of RB1 protein | 15897598 |
| C009687 | wortmannin | wortmannin inhibits the reaction [KITL protein results in increased phosphorylation of RB1 protein] | 10849422 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Vanadates results in increased phosphorylation of RB1 protein] | 14971663 |
| D015032 | Zinc | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RB1 mRNA | 16979875 |
| D019345 | Zinc Acetate | [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA | 16357179 |
| D019345 | Zinc Acetate | Zinc Acetate results in decreased expression of RB1 mRNA | 16357179 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in decreased expression of RB1 mRNA | 12756304 |
| C410228 | ZK159222 | ZK159222 inhibits the reaction [Calcitriol results in increased expression of RB1 protein] | 14729647 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0000987 | proximal promoter sequence-specific DNA binding | - | IDA | 15735762 |
| GO:0001012 | RNA polymerase II regulatory region DNA binding | - | IBA | 21873635 |
| GO:0001078 | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | CONTRIBUTES_TO | IBA | 21873635 |
| GO:0001102 | RNA polymerase II activating transcription factor binding | - | IBA | 21873635 |
| GO:0001102 | RNA polymerase II activating transcription factor binding | - | IEA | - |
| GO:0003677 | DNA binding | - | TAS | 3657987 |
| GO:0003700 | DNA-binding transcription factor activity | - | TAS | 3657987 |
| GO:0003713 | transcription coactivator activity | - | NAS | 15572661 |
| GO:0005515 | protein binding | - | IPI | 1331501 1870208 2138977 2153075 2162480 2189724 7503932 7592647 7651420 7664264 7791904 7890747 7923370 8384581 8386265 8551580 8617242 8756624 9067421 9374493 9395244 9448006 9468139 9468140 9608663 9697699 9858607 9881977 10228159 10613832 10779361 10783144 10944455 11073990 11226179 11268000 11571652 11713253 12037672 12434308 12743606 12813456 12891711 14555653 14645241 15084261 15107404 15542589 16061792 16249186 16286473 16360038 16374512 16510145 16616919 16763564 16766265 16964284 17045206 17274640 17292836 17349581 17380128 17540172 17620057 18391203 19017275 19249677 19513100 19651603 20088881 20195357 20870719 20871633 21119616 21139044 21903422 21952639 22157815 22366686 22615382 22773103 22810586 23472054 23602568 23752268 23783631 23859194 24823443 25609649 25814554 |
| GO:0008134 | transcription factor binding | - | IPI | 16360038 19223331 |
| GO:0019900 | kinase binding | - | IDA | 16286473 |
| GO:0031625 | ubiquitin protein ligase binding | - | IPI | 10944455 |
| GO:0042802 | identical protein binding | - | IPI | 8288605 16360038 |
| GO:0050681 | androgen receptor binding | - | NAS | 15572661 |
| GO:0051219 | phosphoprotein binding | - | IPI | 16360038 |
| GO:0061676 | importin-alpha family protein binding | - | IPI | 12695505 |
| GO:0097718 | disordered domain specific binding | - | IPI | 8245034 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0000082 | G1/S transition of mitotic cell cycle | - | TAS | - |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | - | TAS | 19149898 |
| GO:0001558 | regulation of cell growth | - | IEA | - |
| GO:0001894 | tissue homeostasis | - | IEA | - |
| GO:0003180 | aortic valve morphogenesis | - | ISS | - |
| GO:0006338 | chromatin remodeling | - | TAS | 19149898 |
| GO:0006351 | transcription, DNA-templated | - | IEA | - |
| GO:0006355 | regulation of transcription, DNA-templated | - | NAS | 2730637 |
| GO:0006469 | negative regulation of protein kinase activity | - | IPI | 9858607 |
| GO:0007050 | cell cycle arrest | - | TAS | 19149898 |
| GO:0007093 | mitotic cell cycle checkpoint | - | TAS | 9529249 |
| GO:0007265 | Ras protein signal transduction | - | IEP | 9054499 |
| GO:0007346 | regulation of mitotic cell cycle | - | IBA | 21873635 |
| GO:0007346 | regulation of mitotic cell cycle | - | IMP | 20551165 |
| GO:0010629 | negative regulation of gene expression | - | IMP | 25100735 |
| GO:0016032 | viral process | - | IEA | - |
| GO:0030154 | cell differentiation | - | IBA | 21873635 |
| GO:0030182 | neuron differentiation | - | IBA | 21873635 |
| GO:0030521 | androgen receptor signaling pathway | - | NAS | 15572661 |
| GO:0031134 | sister chromatid biorientation | - | IMP | 20551165 |
| GO:0031175 | neuron projection development | - | IBA | 21873635 |
| GO:0031175 | neuron projection development | - | IEA | - |
| GO:0034088 | maintenance of mitotic sister chromatid cohesion | - | IMP | 20551165 |
| GO:0034349 | glial cell apoptotic process | - | IEA | - |
| GO:0035914 | skeletal muscle cell differentiation | - | IEA | - |
| GO:0042551 | neuron maturation | - | IEA | - |
| GO:0043353 | enucleate erythrocyte differentiation | - | IEA | - |
| GO:0043433 | negative regulation of DNA-binding transcription factor activity | - | TAS | 9529249 |
| GO:0043550 | regulation of lipid kinase activity | - | IDA | 16286473 |
| GO:0045445 | myoblast differentiation | - | IMP | 15541338 |
| GO:0045651 | positive regulation of macrophage differentiation | - | IEA | - |
| GO:0045842 | positive regulation of mitotic metaphase/anaphase transition | - | IMP | 20551165 |
| GO:0045879 | negative regulation of smoothened signaling pathway | - | IEA | - |
| GO:0045892 | negative regulation of transcription, DNA-templated | - | IDA | 10783144 12065415 19223331 |
| GO:0045892 | negative regulation of transcription, DNA-templated | - | TAS | 19149898 |
| GO:0045893 | positive regulation of transcription, DNA-templated | - | NAS | 15572661 |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | - | IEA | - |
| GO:0048565 | digestive tract development | - | IEA | - |
| GO:0048667 | cell morphogenesis involved in neuron differentiation | - | IBA | 21873635 |
| GO:0048667 | cell morphogenesis involved in neuron differentiation | - | IEA | - |
| GO:0050680 | negative regulation of epithelial cell proliferation | - | IEA | - |
| GO:0050728 | negative regulation of inflammatory response | - | ISS | - |
| GO:0051146 | striated muscle cell differentiation | - | IEA | - |
| GO:0051301 | cell division | - | IEA | - |
| GO:0051402 | neuron apoptotic process | - | IEA | - |
| GO:0071459 | protein localization to chromosome, centromeric region | - | IMP | 20551165 |
| GO:0071466 | cellular response to xenobiotic stimulus | - | IEA | - |
| GO:0071922 | regulation of cohesin loading | - | IMP | 20551165 |
| GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle | - | TAS | 19149898 |
| GO:0090230 | regulation of centromere complex assembly | - | TAS | 20551165 |
| GO:0097284 | hepatocyte apoptotic process | - | IEA | - |
| GO:1903055 | positive regulation of extracellular matrix organization | - | ISS | - |
| GO:1904028 | positive regulation of collagen fibril organization | - | ISS | - |
| GO:1904761 | negative regulation of myofibroblast differentiation | - | ISS | - |
| GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | - | IBA | 21873635 |
| GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | - | TAS | 19149898 |
| GO:2000679 | positive regulation of transcription regulatory region DNA binding | - | IDA | 25100735 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0000785 | chromatin | - | IBA | 21873635 |
| GO:0000785 | chromatin | - | TAS | 3657987 |
| GO:0005634 | nucleus | COLOCALIZES_WITH | IBA | 21873635 |
| GO:0005634 | nucleus | - | IDA | 17540172 |
| GO:0005634 | nucleus | - | NAS | 2730637 |
| GO:0005654 | nucleoplasm | - | IDA | 8245034 |
| GO:0005654 | nucleoplasm | - | TAS | - |
| GO:0005667 | transcription factor complex | - | IBA | 21873635 |
| GO:0005819 | spindle | - | IEA | - |
| GO:0008024 | cyclin/CDK positive transcription elongation factor complex | colocalizes_with | IDA | 12037672 |
| GO:0016514 | SWI/SNF complex | - | TAS | 19149898 |
| GO:0016605 | PML body | - | IDA | 9448006 |
| GO:0035189 | Rb-E2F complex | - | IBA | 21873635 |
| GO:0035189 | Rb-E2F complex | - | IDA | 8245034 |
| GO:0035189 | Rb-E2F complex | - | TAS | 19149898 |
| KEGG ID | KEGG Term |
|---|---|
| hsa04110 | Cell cycle |
| hsa05200 | Pathways in cancer |
| hsa05212 | Pancreatic cancer |
| hsa05214 | Glioma |
| hsa05215 | Prostate cancer |
| hsa05218 | Melanoma |
| hsa05219 | Bladder cancer |
| hsa05220 | Chronic myeloid leukemia |
| hsa05222 | Small cell lung cancer |
| hsa05223 | Non-small cell lung cancer |
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-HSA-113501 | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | TAS |
| R-HSA-113501 | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | IEA |
| R-HSA-113510 | E2F mediated regulation of DNA replication | TAS |
| R-HSA-113510 | E2F mediated regulation of DNA replication | IEA |
| R-HSA-1640170 | Cell Cycle | TAS |
| R-HSA-1640170 | Cell Cycle | IEA |
| R-HSA-212436 | Generic Transcription Pathway | IEA |
| R-HSA-2262752 | Cellular responses to stress | TAS |
| R-HSA-2299718 | Condensation of Prophase Chromosomes | TAS |
| R-HSA-2559583 | Cellular Senescence | TAS |
| R-HSA-2559584 | Formation of Senescence-Associated Heterochromatin Foci (SAHF) | TAS |
| R-HSA-2559585 | Oncogene Induced Senescence | TAS |
| R-HSA-2559586 | DNA Damage/Telomere Stress Induced Senescence | TAS |
| R-HSA-453279 | Mitotic G1-G1/S phases | TAS |
| R-HSA-453279 | Mitotic G1-G1/S phases | IEA |
| R-HSA-68875 | Mitotic Prophase | TAS |
| R-HSA-68886 | M Phase | TAS |
| R-HSA-69200 | Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | TAS |
| R-HSA-69202 | Cyclin E associated events during G1/S transition | TAS |
| R-HSA-69206 | G1/S Transition | TAS |
| R-HSA-69206 | G1/S Transition | IEA |
| R-HSA-69231 | Cyclin D associated events in G1 | TAS |
| R-HSA-69236 | G1 Phase | TAS |
| R-HSA-69242 | S Phase | TAS |
| R-HSA-69278 | Cell Cycle, Mitotic | TAS |
| R-HSA-69278 | Cell Cycle, Mitotic | IEA |
| R-HSA-69656 | Cyclin A:Cdk2-associated events at S phase entry | TAS |
| R-HSA-73857 | RNA Polymerase II Transcription | IEA |
| R-HSA-74160 | Gene expression (Transcription) | IEA |
| R-HSA-8878166 | Transcriptional regulation by RUNX2 | IEA |
| R-HSA-8940973 | RUNX2 regulates osteoblast differentiation | IEA |
| R-HSA-8941326 | RUNX2 regulates bone development | IEA |
| R-HSA-8953897 | Cellular responses to external stimuli | TAS |
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