Gene info: ID 5950

Gene: RBP4

GENE ID: 5950

Synonyms: MCOPCB10|RDCCAS

Description: retinol binding protein 4

Gene type: protein-coding

Location: 10q23.33

dbXrefs: Ensembl:ENSG00000138207 MIM:180250 Vega:OTTHUMG00000018773 UniprotKB:P02753

RefSeq: NG_009104.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 18

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 5.805e-1 (AD) 3.599e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
NSG2	0.926
AP1S1	0.914
PNCK	0.913
CGREF1	0.904
TCEAL6	0.903
BSCL2	0.902
ACTR3B	0.901
C2orf80	0.899
DTNB	0.895
TMEM130	0.894

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.558
OR4F29	-0.507
REST	-0.467
RAI14	-0.466
CTNNA3	-0.456
CPM	-0.447
MAGEA12	-0.444
CXCR2	-0.436
FZD10	-0.434
TFPI	-0.432

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00755	Tretinoin	Small Molecule	302-79-4	Approved\|Investigational\|Nutraceutical	Target
DB00162	Vitamin A	Small Molecule	68-26-8	Approved\|Nutraceutical	Carrier
DB03917	N-Ethyl Retinamide	Small Molecule		Experimental	Carrier
DB05076	Fenretinide	Small Molecule	65646-68-6	Investigational	Carrier
DB06985	2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid	Small Molecule		Experimental	Carrier

ID	Drug Name	Action	PubMed
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in increased expression of RBP4 protein"	27092574
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RBP4 mRNA"	23994337
C026308	3,4-dihydrocoumarin	"3,4-dihydrocoumarin results in decreased expression of RBP4 mRNA"	22016648
D000082	Acetaminophen	Acetaminophen results in decreased expression of RBP4 mRNA	29067470
D000082	Acetaminophen	Acetaminophen results in decreased expression of RBP4 protein	16687475
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of RBP4 protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of RBP4 mRNA	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased methylation of RBP4 gene	27153756
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of RBP4 mRNA	16483693
C023650	aniline	aniline results in increased expression of RBP4 mRNA	22016648
C547126	AZM551248	AZM551248 results in increased expression of RBP4 mRNA	22323515
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of RBP4 mRNA	23994337
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of RBP4 mRNA	22209252\|2600196
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of RBP4 mRNA	22228805
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of RBP4 mRNA	21839799
D001599	Berberine	Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D019207	beta Carotene	beta Carotene results in decreased expression of and results in decreased secretion of RBP4 protein	22542753
D019207	beta Carotene	beta Carotene results in decreased expression of and results in decreased secretion of RBP4 protein	22542753
D004958	Estradiol	Estradiol affects the expression of RBP4 mRNA	14699072
D004958	Estradiol	Estradiol results in increased expression of and results in increased secretion of RBP4 protein	17456573
D004958	Estradiol	Estradiol results in increased expression of RBP4 mRNA	17456573
D004958	Estradiol	Estradiol results in increased expression of RBP4 protein	18191855
D004958	Estradiol	[Progesterone co-treated with Estradiol] results in increased expression of RBP4 mRNA	17404688
D004958	Estradiol	Estradiol results in decreased expression of RBP4 mRNA	19484750
C006780	bisphenol A	bisphenol A results in increased expression of RBP4 mRNA	26364221
C006780	bisphenol A	bisphenol A affects the expression of RBP4 mRNA	21786754
C006780	bisphenol A	bisphenol A results in decreased expression of RBP4 mRNA	12075121
C006780	bisphenol A	bisphenol A results in increased expression of RBP4 mRNA	25181051
C025703	bleomycetin	bleomycetin results in decreased expression of RBP4 mRNA	21040473
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of RBP4 mRNA	21457566
C034939	cadmium sulfide	[cadmium telluride co-treated with cadmium sulfide] results in increased expression of RBP4 mRNA	20596552
C028337	cadmium telluride	[cadmium telluride co-treated with cadmium sulfide] results in increased expression of RBP4 mRNA	20596552
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of RBP4 mRNA	17484886
D002273	Carcinogens	Carcinogens results in decreased expression of RBP4 mRNA	16316942
D004390	Chlorpyrifos	Chlorpyrifos affects the expression of RBP4 mRNA	26775027
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RBP4 gene	20938992
C012843	cinnamic aldehyde	cinnamic aldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D003300	Copper	Copper affects the expression of RBP4 protein	17192175
D019327	Copper Sulfate	Copper Sulfate results in decreased expression of RBP4 mRNA	19549813
C009160	cyclonite	cyclonite results in increased expression of RBP4 mRNA	25559034
D016572	Cyclosporine	Cyclosporine results in decreased expression of RBP4 mRNA	20106945\|2556210
C014347	decitabine	decitabine results in increased expression of RBP4 mRNA	16367923
D003907	Dexamethasone	Dexamethasone results in increased expression of RBP4 mRNA	19853017\|2504701
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of RBP4 mRNA	28628672
C023614	dibenzofuran	dibenzofuran analog results in increased expression of RBP4 mRNA	20566336
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of RBP4 mRNA	21266533
D002945	Cisplatin	Cisplatin results in decreased expression of RBP4 mRNA	27392435
D004041	Dietary Fats	Dietary Fats results in decreased expression of RBP4 mRNA	18042831\|2501614
D004041	Dietary Fats	Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D004041	Dietary Fats	cinnamic aldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D004041	Dietary Fats	[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein	19080170
D004041	Dietary Fats	Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D004041	Dietary Fats	Dietary Fats results in increased expression of RBP4 protein	21739664
D004041	Dietary Fats	resveratrol inhibits the reaction [Dietary Fats results in increased expression of RBP4 protein]	21739664
D019813	1,2-Dimethylhydrazine	"[APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of RBP4 mRNA"	27840820
D004237	Diuron	Diuron results in decreased expression of RBP4 mRNA	25152437
D004317	Doxorubicin	Doxorubicin results in increased expression of RBP4 mRNA	22016648
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of RBP4 mRNA	20227414
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of RBP4 mRNA	17606305
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of RBP4 mRNA	17555576
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of RBP4 mRNA	12075121
C098546	ethyl tert-butyl ether	ethyl tert-butyl ether results in increased expression of RBP4 protein	24090815
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RBP4 gene	20938992
D004397	Fonofos	Fonofos results in increased methylation of RBP4 promoter	22847954
D019833	Genistein	Genistein results in increased expression of RBP4 mRNA	20884965
D019833	Genistein	Genistein results in decreased expression of RBP4 mRNA	12075121
D005839	Gentamicins	Gentamicins results in increased expression of RBP4 protein	21081137\|2206182
C412815	GW 4064	GW 4064 results in increased expression of RBP4 mRNA	26655953
D017313	Fenretinide	Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]	21591606
D017313	Fenretinide	Fenretinide binds to RBP4 protein	21591606
D017313	Fenretinide	[Fenretinide binds to RBP4 protein] inhibits the reaction [RBP4 protein binds to TTR protein]	21591606
D017313	Fenretinide	Fenretinide results in decreased expression of RBP4 mRNA	28973697
C029424	hydrazine	hydrazine results in increased expression of RBP4 mRNA	15282401
C075954	indolo(3,2-b)carbazole	"indolo(3,2-b)carbazole results in increased expression of RBP4 mRNA"	23994337
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of RBP4 mRNA	28628672
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RBP4 mRNA	25613284
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of RBP4 mRNA	28628672
C544151	jinfukang	jinfukang results in decreased expression of RBP4 mRNA	27392435
C098607	JP8 aviation fuel	JP8 aviation fuel results in decreased expression of RBP4 mRNA	15618438
D008687	Metformin	Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RBP4 gene	20938992
C004925	methylmercuric chloride	methylmercuric chloride results in decreased expression of RBP4 mRNA	23179753
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of RBP4 mRNA	27544571
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of RBP4 mRNA	16966085
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of RBP4 mRNA"	26251327
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in increased methylation of RBP4 promoter"	26251327
D008770	Methylnitrosourea	Methylnitrosourea results in increased expression of RBP4 mRNA	16525678
C043243	methyl tert-butyl ether	methyl tert-butyl ether affects the expression of RBP4 mRNA	24128854
D015735	Mifepristone	Mifepristone inhibits the reaction [Progesterone results in decreased expression of RBP4 mRNA]	27264040
C523799	MRK 003	RBP4 results in decreased susceptibility to MRK 003	19903844
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog affects the expression of RBP4 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of RBP4 mRNA"	25554681
C007350	nitrofen	nitrofen results in decreased expression of RBP4 protein	22015466
C025589	ochratoxin A	ochratoxin A results in decreased expression of RBP4 mRNA	16251485
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of RBP4 mRNA	25729387
C030110	oxaliplatin	oxaliplatin results in increased expression of RBP4 mRNA	25729387
D000073878	Palm Oil	Palm Oil results in decreased expression of RBP4 mRNA	18042831
D010278	Parathion	Parathion results in increased methylation of RBP4 promoter	22847954
C522391	perfluorododecanoic acid	perfluorododecanoic acid results in increased expression of RBP4 protein	26168851
C101814	perfluoro-n-undecanoic acid	perfluoro-n-undecanoic acid results in decreased expression of RBP4 mRNA	23602845
D010670	Phenylthiourea	Phenylthiourea results in decreased expression of RBP4 mRNA	16929533\|1831603
D010670	Phenylthiourea	Phenylthiourea results in decreased expression of RBP4 protein	18316031
C006253	pirinixic acid	pirinixic acid results in decreased expression of RBP4 mRNA	20813756
D010936	Plant Extracts	Plant Extracts results in decreased expression of RBP4 mRNA	23557933
D011192	Potassium Dichromate	Potassium Dichromate affects the expression of RBP4 mRNA	23608068
D011374	Progesterone	Progesterone results in increased expression of RBP4 mRNA	23018184
D011374	Progesterone	[Progesterone co-treated with Estradiol] results in increased expression of RBP4 mRNA	17404688
D011374	Progesterone	Progesterone results in increased expression of RBP4 mRNA	17404688
D011374	Progesterone	Mifepristone inhibits the reaction [Progesterone results in decreased expression of RBP4 mRNA]	27264040
D011374	Progesterone	Progesterone results in decreased expression of RBP4 mRNA	27264040
D011374	Progesterone	[Progesterone results in increased activity of PGR protein] which results in decreased expression of RBP4 mRNA	15845616
D011374	Progesterone	Progesterone affects the expression of RBP4 protein	11833939
D011794	Quercetin	Quercetin results in decreased expression of RBP4 mRNA	21632981
C059514	resveratrol	resveratrol results in decreased expression of RBP4 mRNA	21109418
C059514	resveratrol	resveratrol inhibits the reaction [Dietary Fats results in increased expression of RBP4 protein]	21739664
C059514	resveratrol	resveratrol results in decreased expression of RBP4 protein	21575630
C089730	rosiglitazone	rosiglitazone results in increased expression of RBP4 mRNA	26670611
D012402	Rotenone	Rotenone results in increased expression of RBP4 mRNA	22016648
D012822	Silicon Dioxide	Silicon Dioxide analog results in decreased expression of RBP4 mRNA	25895662
D012834	Silver	Silver results in increased expression of RBP4 mRNA	27131904
D013311	Streptozocin	Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D013311	Streptozocin	cinnamic aldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D013311	Streptozocin	[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein	19080170
D013311	Streptozocin	Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]	19080170
D012460	Sulfasalazine	Sulfasalazine affects the expression of RBP4 mRNA	22016648
D013629	Tamoxifen	Tamoxifen affects the expression of RBP4 mRNA	17555576
C012568	terbufos	terbufos results in increased methylation of RBP4 promoter	22847954
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in decreased expression of RBP4 mRNA	18976794
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of RBP4 mRNA	16443690\|1849575
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of RBP4 mRNA	21570461\|2637764
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of RBP4 mRNA	23994337
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of RBP4 protein	27105554
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of RBP4 mRNA	15644576
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RBP4 mRNA	25613284
D013792	Thalidomide	Thalidomide results in decreased expression of RBP4 mRNA	28892372
C009495	titanium dioxide	titanium dioxide affects the expression of RBP4 mRNA	17656681
C009495	titanium dioxide	titanium dioxide results in decreased expression of RBP4 mRNA	23557971
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of RBP4 mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of RBP4 mRNA	25729387
D014212	Tretinoin	Tretinoin results in decreased expression of RBP4 mRNA	20530235
D014212	Tretinoin	Tretinoin binds to RBP4 protein	16461020
C012589	trichostatin A	trichostatin A results in decreased expression of RBP4 mRNA	15901671
D014635	Valproic Acid	Valproic Acid results in decreased expression of RBP4 mRNA	15901671
D014635	Valproic Acid	Valproic Acid affects the expression of RBP4 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased expression of RBP4 mRNA	23179753\|2718838
D014635	Valproic Acid	Valproic Acid results in decreased methylation of RBP4 gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of RBP4 mRNA	23179753\|2800136
D014635	Valproic Acid	Valproic Acid affects the expression of RBP4 mRNA	17963808
C025643	vinclozolin	vinclozolin results in increased expression of RBP4 mRNA	23869203
D014801	Vitamin A	Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]	21591606
D014801	Vitamin A	Vitamin A binds to RBP4 protein	16461020\|1676269
D014801	Vitamin A	Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]	21591606
D014801	Vitamin A	Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein	22542753
D014801	Vitamin A	Vitamin A deficiency results in decreased secretion of RBP4 protein	22001960
D014801	Vitamin A	Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein	22542753
D014801	Vitamin A	Vitamin A results in increased secretion of RBP4 protein	22001960
D002762	Cholecalciferol	Cholecalciferol results in increased expression of RBP4 mRNA	17170073

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005515	protein binding	-	IPI	986177 12228058 21777382
GO:0016918	retinal binding	-	IEA	-
GO:0019841	retinol binding	-	IDA	571335
GO:0034632	retinol transmembrane transporter activity	-	IC	571335
GO:0046982	protein heterodimerization activity	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001523	retinoid metabolic process	-	TAS	-
GO:0001654	eye development	-	IMP	10232633
GO:0001654	eye development	-	ISS	-
GO:0006094	gluconeogenesis	-	IMP	18466349
GO:0006094	gluconeogenesis	-	ISS	-
GO:0007507	heart development	-	ISS	-
GO:0007601	visual perception	-	IEA	-
GO:0030277	maintenance of gastrointestinal epithelium	-	IDA	10944490
GO:0030324	lung development	-	ISS	-
GO:0032024	positive regulation of insulin secretion	-	IMP	16034410
GO:0032526	response to retinoic acid	-	IDA	571335
GO:0034633	retinol transport	-	IC	571335
GO:0042572	retinol metabolic process	-	IMP	10232633
GO:0042593	glucose homeostasis	-	IDA	17003346
GO:0045471	response to ethanol	-	IEA	-
GO:0048562	embryonic organ morphogenesis	-	ISS	-
GO:0048706	embryonic skeletal system development	-	ISS	-
GO:0048738	cardiac muscle tissue development	-	ISS	-
GO:0048807	female genitalia morphogenesis	-	ISS	-
GO:0051024	positive regulation of immunoglobulin secretion	-	ISS	-
GO:0060044	negative regulation of cardiac muscle cell proliferation	-	ISS	-
GO:0060059	embryonic retina morphogenesis in camera-type eye	-	ISS	-
GO:0060065	uterus development	-	ISS	-
GO:0060068	vagina development	-	ISS	-
GO:0060157	urinary bladder development	-	ISS	-
GO:0060347	heart trabecula formation	-	ISS	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	TAS	-
GO:0005615	extracellular space	-	IDA	5132677 12237133 17003346
GO:0005615	extracellular space	-	ISS	-
GO:0005829	cytosol	-	TAS	-
GO:0032991	protein-containing complex	-	IEA	-
GO:0070062	extracellular exosome	-	HDA	19056867 23533145

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-162582	Signal Transduction	TAS
R-HSA-1643685	Disease	TAS
R-HSA-196854	Metabolism of vitamins and cofactors	TAS
R-HSA-2187338	Visual phototransduction	TAS
R-HSA-2453864	Retinoid cycle disease events	TAS
R-HSA-2453902	The canonical retinoid cycle in rods (twilight vision)	TAS
R-HSA-2474795	Diseases associated with visual transduction	TAS
R-HSA-372790	Signaling by GPCR	TAS
R-HSA-388396	GPCR downstream signalling	TAS
R-HSA-418594	G alpha (i) signalling events	TAS
R-HSA-5663202	Diseases of signal transduction	TAS
R-HSA-6806667	Metabolism of fat-soluble vitamins	TAS
R-HSA-6809583	Retinoid metabolism disease events	TAS
R-HSA-975634	Retinoid metabolism and transport	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
21442217	Circulating retinol-binding protein 4 and metabolic syndrome in the elderly. (2011 Nov)	Mostafaie N	Wien Med Wochenschr
20832065	Relation between retinol, retinol-binding protein 4, transthyretin and carotid intima media thickness. (2010 Dec)	Bobbert T	Atherosclerosis
25633269	First trimester placental retinol-binding protein 4 (RBP4) and pregnancy-associated placental protein A (PAPP-A) in the prediction of early-onset severe pre-eclampsia. (2015 Apr)	Yliniemi A	Metabolism
29482216	Association of Serum Retinol-Binding Protein 4 Concentration With Risk for and Prognosis of Amyotrophic Lateral Sclerosis. (2018 May 1)	Rosenbohm A	JAMA Neurol
22587616	Associations between retinol-binding protein 4 and cardiometabolic risk factors and subclinical atherosclerosis in recently postmenopausal women: cross-sectional analyses from the KEEPS study. (2012 May 15)	Huang G	Cardiovasc Diabetol
25479076	A genetic polymorphism in RBP4 is associated with coronary artery disease. (2014 Dec 3)	Wan K	Int J Mol Sci
24843606	Increased plasma levels of retinol-binding protein 4 with visceral obesity is associated with cardiovascular risk factors. (2012 Oct 18)	Won JC	J Diabetes Investig
29120147	The Association Between Retinol-Binding Protein 4 and Cardiovascular Risk Score is Mediated by Waist Circumference in Overweight/Obese Adolescent Girls (2017 Mar)	Klisic A	Acta Clin Croat
28888344	Plasma Retinol-Binding Protein 4 Levels and the Risk of Ischemic Stroke among Women. (2018 Jan)	Rist PM	J Stroke Cerebrovasc Dis
19056238	Association of retinol-binding protein-4 with dietary selenium intake and other lifestyle features in young healthy women. (2009 Apr)	Hermsdorff HH	Nutrition
28639612	Elevated serum retinol-binding protein 4 levels are correlated with blood pressure in prehypertensive Chinese. (2017 Oct)	Zhang JX	J Hum Hypertens
26731992	Serum Retinol-Binding Protein-4 Level is a High Risk Factor for Coronary Heart Disease in Chinese. (2015)	Dong H	Clin Lab
22561439	[Serum retinol binding protein 4 and bone metabolism in patients with type 2 diabetes]. (2012 Feb)	Ye A	Zhong Nan Da Xue Xue Bao Yi Xue Ban
19661959	Combined impact of adiponectin and retinol-binding protein 4 on metabolic syndrome in elderly people: the Korean Longitudinal Study on Health and Aging. (2010 Apr)	Lim S	Obesity (Silver Spring)
18362299	Retinol-binding protein 4 is associated with insulin resistance, but appears unsuited for metabolic screening in women with polycystic ovary syndrome. (2008 Apr)	Mohlig M	Eur J Endocrinol
25922846	Relationship between serum 25-hydroxyvitamin D and lower extremity arterial disease in type 2 diabetes mellitus patients and the analysis of the intervention of vitamin D. (2015)	Zhou W	J Diabetes Res
17292720	Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents. (2007 Mar)	Lee DC	Metabolism
24372548	The complex P2X7 receptor/inflammasome in perivascular fat tissue of heavy smokers. (2014)	Rossi C	Eur J Clin Invest