Gene: RPL32

6161
L32|PP9932
ribosomal protein L32
protein-coding
3p25.2
Ensembl:ENSG00000144713 Vega:OTTHUMG00000129804 UniprotKB:P62910
NC_000003.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.168e-2 (AD)  2.484e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RPS110.986
RPS100.986
RPL190.983
RPL37A0.983
RPL270.982
RPL110.982
RPL13A0.981
RPL310.981
RPS120.981
RPS240.98

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.8
OR4F5-0.753
PCDHAC1-0.229
KCNH1-0.213
PLEKHD1-0.213
NCR3LG1-0.211
OPRD1-0.209
KCNH5-0.208
PCDHA5-0.206
GDF7-0.205

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5532941-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one"1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [EIF4G1 protein binds to RPL32 mRNA]"25940091
C5532941-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one"1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one promotes the reaction [LARP1 protein binds to RPL32 mRNA]"25940091
C5532941-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one"1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one results in decreased expression of RPL32 protein"25940091
C5532941-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one"LARP1 protein promotes the reaction [1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one results in decreased expression of RPL32 protein]"25940091
C0364231-aminomethylphosphonic acid[Herbicides co-treated with 1-aminomethylphosphonic acid] results in increased expression of RPL32 mRNA20566314
C4727913-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of RPL32 mRNA12958071
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of RPL32 mRNA"18648102
C0652504-hydroxy-equilenin4-hydroxy-equilenin results in increased expression of RPL32 mRNA15135645
D000082AcetaminophenAcetaminophen affects the expression of RPL32 mRNA17562736
D000596Amino AcidsAmino Acids deficiency results in decreased expression of RPL32 protein25940091
D000596Amino AcidsLARP1 protein promotes the reaction [Amino Acids results in decreased expression of RPL32 protein]25940091
D000638AmiodaroneAmiodarone affects the expression of RPL32 mRNA19483382
D000643Ammonium ChlorideAmmonium Chloride affects the expression of RPL32 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of RPL32 mRNA24449571
D001151ArsenicArsenic affects the methylation of RPL32 gene25304211
D001280AtrazineAtrazine results in decreased expression of RPL32 mRNA22378314
D001553BenzbromaroneBenzbromarone affects the expression of RPL32 mRNA19483382
D004958EstradiolEstradiol results in decreased expression of RPL32 mRNA23019147
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of RPL32 mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of RPL32 mRNA25594700
C006780bisphenol Abisphenol A results in increased expression of RPL32 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RPL32 mRNA28628672
D002104CadmiumCadmium results in increased oxidation of RPL32 protein24077948
D019256Cadmium ChlorideCadmium Chloride affects the expression of RPL32 mRNA18409656
C100187chloropicrinchloropicrin affects the expression of RPL32 mRNA26352163
D002994ClofibrateClofibrate results in increased expression of RPL32 mRNA17585979
D002994ClofibrateClofibrate affects the expression of RPL32 mRNA19483382
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RPL32 mRNA17602206
D003042CocaineCocaine affects the expression of RPL32 mRNA20187946
D003300CopperCopper results in increased expression of RPL32 mRNA18522721
D003300CopperCopper results in increased expression of RPL32 mRNA25646894
C029892cupric chloridecupric chloride affects the expression of RPL32 mRNA17211630
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of RPL32 mRNA]27941970
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of RPL32 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RPL32 mRNA28628672
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of RPL32 mRNA17379624
D004041Dietary Fats[Dietary Fats co-treated with resveratrol] results in decreased expression of RPL32 mRNA21852083
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of RPL32 mRNA17942915
D004052DiethylnitrosamineMET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL32 mRNA]17942915
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RPL32 mRNA17602206
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RPL32 protein23301498
D005001EthionineEthionine affects the expression of RPL32 mRNA19483382
C007738fluoranthene[fluoranthene co-treated with Permethrin] results in decreased expression of RPL32 mRNA22406618
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of RPL32 mRNA22634610
D006540Herbicides[Herbicides co-treated with 1-aminomethylphosphonic acid] results in increased expression of RPL32 mRNA20566314
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of RPL32 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RPL32 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of RPL32 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RPL32 mRNA28628672
D008777MethyltestosteroneMethyltestosterone results in decreased expression of RPL32 mRNA29191790
D009532NickelNickel results in decreased expression of RPL32 mRNA24084258
C484027oligofectamineoligofectamine results in increased expression of RPL32 mRNA14668052
D009853OmeprazoleOmeprazole affects the expression of RPL32 mRNA19483382
D010433Pentylenetetrazole[Pentylenetetrazole co-treated with Vigabatrin] affects the expression of RPL32 mRNA21503142
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of RPL32 protein26879310
D026023Permethrin[fluoranthene co-treated with Permethrin] results in decreased expression of RPL32 mRNA22406618
D026023PermethrinPermethrin results in decreased expression of RPL32 mRNA22406618
D010862PilocarpinePilocarpine promotes the reaction [EIF2S1 protein modified form results in decreased expression of RPL32 protein]16492139
C006253pirinixic acidpirinixic acid affects the expression of RPL32 mRNA19483382
D010936Plant ExtractsPlant Extracts results in increased expression of RPL32 mRNA23557933
C045950propiconazolepropiconazole results in increased expression of RPL32 mRNA21278054
D011441PropylthiouracilPropylthiouracil affects the expression of RPL32 mRNA19483382
C059514resveratrol[Dietary Fats co-treated with resveratrol] results in decreased expression of RPL32 mRNA21852083
D020123SirolimusLARP1 protein promotes the reaction [Sirolimus results in decreased expression of RPL32 protein]25940091
D020123SirolimusSirolimus inhibits the reaction [EIF4G1 protein binds to RPL32 mRNA]25940091
D020123SirolimusSirolimus promotes the reaction [LARP1 protein binds to RPL32 mRNA]25940091
D020123SirolimusSirolimus results in decreased expression of RPL32 protein25940091
D018038Sodium SeleniteSodium Selenite results in increased expression of RPL32 mRNA18175754
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RPL32 mRNA18796159
D013853ThioacetamideThioacetamide affects the expression of RPL32 mRNA19483382
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of RPL32 mRNA28065790
C024746tobacco tartobacco tar results in decreased expression of RPL32 mRNA19559774
D014241TrichloroethyleneTrichloroethylene results in increased methylation of RPL32 gene27618143
D014520UrethaneUrethane results in increased expression of RPL32 mRNA16289808
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid affects the expression of RPL32 mRNA18422935
D001335Vehicle EmissionsVehicle Emissions affects the methylation of RPL32 gene25560391
D020888Vigabatrin[Pentylenetetrazole co-treated with Vigabatrin] affects the expression of RPL32 mRNA21503142

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22658674  
GO:0003735structural constituent of ribosome-NAS12962325  
GO ID GO Term Qualifier Evidence PubMed
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-TAS-  
GO:0002181cytoplasmic translation-IDA25957688  
GO:0006412translation-NAS12962325  
GO:0006413translational initiation-TAS-  
GO:0006614SRP-dependent cotranslational protein targeting to membrane-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005829cytosol-TAS-  
GO:0016020membrane-HDA19946888  
GO:0022625cytosolic large ribosomal subunit-HDA12962325  
GO:0022625cytosolic large ribosomal subunit-IBA21873635  
GO:0022625cytosolic large ribosomal subunit-IDA25957688  
GO:0042788polysomal ribosome-IDA25957688  
KEGG ID KEGG Term
hsa03010Ribosome
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyIEA
R-HSA-1430728MetabolismIEA
R-HSA-156827L13a-mediated translational silencing of Ceruloplasmin expressionTAS
R-HSA-156842Eukaryotic Translation ElongationIEA
R-HSA-156902Peptide chain elongationIEA
R-HSA-1643685DiseaseTAS
R-HSA-168254Influenza InfectionTAS
R-HSA-168255Influenza Life CycleTAS
R-HSA-168273Influenza Viral RNA Transcription and ReplicationTAS
R-HSA-1799339SRP-dependent cotranslational protein targeting to membraneIEA
R-HSA-1799339SRP-dependent cotranslational protein targeting to membraneTAS
R-HSA-192823Viral mRNA TranslationTAS
R-HSA-2408522Selenoamino acid metabolismIEA
R-HSA-2408557Selenocysteine synthesisIEA
R-HSA-376176Signaling by ROBO receptorsIEA
R-HSA-392499Metabolism of proteinsTAS
R-HSA-392499Metabolism of proteinsIEA
R-HSA-422475Axon guidanceIEA
R-HSA-5663205Infectious diseaseTAS
R-HSA-6791226Major pathway of rRNA processing in the nucleolus and cytosolTAS
R-HSA-71291Metabolism of amino acids and derivativesIEA
R-HSA-72312rRNA processingTAS
R-HSA-72613Eukaryotic Translation InitiationTAS
R-HSA-72689Formation of a pool of free 40S subunitsTAS
R-HSA-72706GTP hydrolysis and joining of the 60S ribosomal subunitTAS
R-HSA-72737Cap-dependent Translation InitiationTAS
R-HSA-72764Eukaryotic Translation TerminationIEA
R-HSA-72766TranslationTAS
R-HSA-72766TranslationIEA
R-HSA-8868773rRNA processing in the nucleus and cytosolTAS
R-HSA-8953854Metabolism of RNATAS
R-HSA-9010553Regulation of expression of SLITs and ROBOsIEA
R-HSA-927802Nonsense-Mediated Decay (NMD)TAS
R-HSA-975956Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)TAS
R-HSA-975957Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18671841PSMB2 and RPL32 are suitable denominators to normalize gene expression profiles in bronchoalveolar cells. (2008 Jul 31)Kriegova EBMC Mol Biol