Gene: RPS11

6205
S11
ribosomal protein S11
protein-coding
19q13.33
Ensembl:ENSG00000142534 MIM:180471 Vega:OTTHUMG00000183156 UniprotKB:P62280
NC_000019.10
PubMed
0   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.791e-1 (AD)  6.522e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RPL13A0.991
RPL190.986
RPL320.986
RPS250.984
RPL270.981
RPL240.98
RPS160.98
RPL100.979
RPL340.978
RPS100.978

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.843
OR4F5-0.8
PCDHAC1-0.23
KCNH1-0.216
NCR3LG1-0.211
KCNH5-0.207
PCDHA5-0.206
PCDHAC2-0.206
PPM1E-0.205
CDH7-0.205

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0364231-aminomethylphosphonic acid"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RPS11 mRNA"20566314
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of RPS11 mRNA"21346803
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS11 mRNA"15215175
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RPS11 mRNA"28973690
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of RPS11 mRNA"18648102
C043377acetochlor"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RPS11 mRNA"20566314
D000643Ammonium ChlorideAmmonium Chloride affects the expression of RPS11 mRNA16483693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of RPS11 mRNA20498004
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RPS11 mRNA"20018196
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of RPS11 mRNA"19150397
D004958EstradiolEstradiol results in increased expression of RPS11 mRNA17823450
C006780bisphenol Abisphenol A affects the expression of RPS11 mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of RPS11 mRNA26512966
C006780bisphenol Abisphenol A results in increased expression of RPS11 mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of RPS11 mRNA18958704
D000069286BortezomibBortezomib results in increased expression of RPS11 mRNA20977926
C013418bromfenacoumbromfenacoum results in decreased expression of RPS11 protein28903499
C032036bromobenzenebromobenzene results in increased expression of RPS11 mRNA12628495
D019256Cadmium ChlorideCadmium Chloride results in increased expression of RPS11 mRNA23741332
D002235Carbofuran[Lindane co-treated with metolachlor co-treated with Carbofuran] results in increased expression of RPS11 mRNA21075942
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of RPS11 mRNA15963342
D002713Chlorine[Ozone co-treated with Chlorine] results in decreased expression of RPS11 mRNA18636392
C100187chloropicrinchloropicrin results in increased expression of RPS11 mRNA26352163
C018021cobaltous chloridecobaltous chloride results in increased expression of RPS11 mRNA19376846
D0150842,4-Dichlorophenoxyacetic Acid"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RPS11 mRNA"20566314
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of RPS11 mRNA21266533
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of RPS11 mRNA19041683
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of RPS11 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RPS11 mRNA17942748
D005485FlutamideFlutamide results in increased expression of RPS11 mRNA24136188
C069837fullerene C60fullerene C60 results in decreased expression of RPS11 mRNA19167457
D019833GenisteinGenistein results in decreased expression of RPS11 mRNA15256057
D019833GenisteinGenistein results in increased expression of RPS11 mRNA21782745
D005839GentamicinsGentamicins results in increased expression of RPS11 mRNA22061828
D005897GlafenineGlafenine results in increased expression of RPS11 mRNA24136188
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of RPS11 mRNA22634610
C424943glutamyl-Se-methylselenocysteineglutamyl-Se-methylselenocysteine results in decreased expression of RPS11 mRNA11306469
D006540Herbicides"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RPS11 mRNA"20566314
D006830Hydralazine[Hydralazine co-treated with Valproic Acid] results in increased expression of RPS11 mRNA17183730
D007854LeadLead affects the expression of RPS11 mRNA28903495
D001556Lindane[Lindane co-treated with metolachlor co-treated with Carbofuran] results in increased expression of RPS11 mRNA21075942
C008340mecoprop"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RPS11 mRNA"20566314
D008627Mercuric ChlorideMercuric Chloride affects the expression of RPS11 mRNA20353558
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of RPS11 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of RPS11 mRNA26011545
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA19840844
C051786metolachlor[Lindane co-treated with metolachlor co-treated with Carbofuran] results in increased expression of RPS11 mRNA21075942
C038541N-benzyloxycarbonylprolylprolinalN-benzyloxycarbonylprolylprolinal results in increased expression of RPS11 mRNA21487212
C012655nimesulidenimesulide results in increased expression of RPS11 mRNA24136188
D010126Ozone[Ozone co-treated with Chlorine] results in decreased expression of RPS11 mRNA18636392
C017947sodium arsenitesodium arsenite results in increased expression of RPS11 mRNA20308225
C017947sodium arsenitesodium arsenite results in increased expression of RPS11 mRNA19072884
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RPS11 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of RPS11 mRNA16214954
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RPS11 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RPS11 mRNA18796159
D013755Tetradecanoylphorbol Acetate[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA19840844
C066340tolcaponetolcapone binds to RPS11 protein19783845
D014212TretinoinTretinoin results in increased expression of RPS11 mRNA21934132
D014635Valproic Acid[Hydralazine co-treated with Valproic Acid] results in increased expression of RPS11 mRNA17183730
D014635Valproic AcidValproic Acid results in increased methylation of RPS11 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22658674  
GO:0003735structural constituent of ribosome-IBA21873635  
GO:0005515protein binding-IPI24725412  
GO:0019843rRNA binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-TAS-  
GO:0006412translation-IC8706699  15883184  
GO:0006412translation-NAS1577483  
GO:0006413translational initiation-TAS-  
GO:0006614SRP-dependent cotranslational protein targeting to membrane-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-TAS-  
GO:0005730nucleolus-HDA16791210  
GO:0005737cytoplasm-HDA16791210  
GO:0005829cytosol-TAS-  
GO:0005840ribosome-NAS3267208  
GO:0005925focal adhesion-HDA21423176  
GO:0016020membrane-HDA19946888  
GO:0022627cytosolic small ribosomal subunit-HDA15883184  
GO:0022627cytosolic small ribosomal subunit-IBA21873635  
GO:0022627cytosolic small ribosomal subunit-IDA8706699  
GO:0070062extracellular exosome-HDA19056867  
KEGG ID KEGG Term
hsa03010Ribosome
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyIEA
R-HSA-1430728MetabolismIEA
R-HSA-156827L13a-mediated translational silencing of Ceruloplasmin expressionTAS
R-HSA-156842Eukaryotic Translation ElongationIEA
R-HSA-156902Peptide chain elongationIEA
R-HSA-1643685DiseaseTAS
R-HSA-168254Influenza InfectionTAS
R-HSA-168255Influenza Life CycleTAS
R-HSA-168273Influenza Viral RNA Transcription and ReplicationTAS
R-HSA-1799339SRP-dependent cotranslational protein targeting to membraneIEA
R-HSA-1799339SRP-dependent cotranslational protein targeting to membraneTAS
R-HSA-192823Viral mRNA TranslationTAS
R-HSA-2408522Selenoamino acid metabolismIEA
R-HSA-2408557Selenocysteine synthesisIEA
R-HSA-376176Signaling by ROBO receptorsIEA
R-HSA-392499Metabolism of proteinsTAS
R-HSA-392499Metabolism of proteinsIEA
R-HSA-422475Axon guidanceIEA
R-HSA-5663205Infectious diseaseTAS
R-HSA-6791226Major pathway of rRNA processing in the nucleolus and cytosolTAS
R-HSA-71291Metabolism of amino acids and derivativesIEA
R-HSA-72312rRNA processingTAS
R-HSA-72613Eukaryotic Translation InitiationTAS
R-HSA-72649Translation initiation complex formationTAS
R-HSA-72662Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43STAS
R-HSA-72689Formation of a pool of free 40S subunitsTAS
R-HSA-72695Formation of the ternary complex, and subsequently, the 43S complexTAS
R-HSA-72702Ribosomal scanning and start codon recognitionTAS
R-HSA-72706GTP hydrolysis and joining of the 60S ribosomal subunitTAS
R-HSA-72737Cap-dependent Translation InitiationTAS
R-HSA-72764Eukaryotic Translation TerminationIEA
R-HSA-72766TranslationTAS
R-HSA-72766TranslationIEA
R-HSA-8868773rRNA processing in the nucleus and cytosolTAS
R-HSA-8953854Metabolism of RNATAS
R-HSA-9010553Regulation of expression of SLITs and ROBOsIEA
R-HSA-927802Nonsense-Mediated Decay (NMD)TAS
R-HSA-975956Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)TAS
R-HSA-975957Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal