Gene: BDNF

627
ANON2|BULN2
brain derived neurotrophic factor
protein-coding
11p14.1
Ensembl:ENSG00000176697 MIM:113505 Vega:OTTHUMG00000178797 UniprotKB:P23560
NG_011794.1
PubMed
CD|OD|ND|AD
241   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.643e-2 (AD)  3.918e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NPTX20.825
DUSP60.81
ADCYAP10.783
ST8SIA50.774
DUSP20.769
ARL4D0.768
GPR680.766
HSPB30.762
BEND50.75
PCSK10.749

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PARD3B-0.514
MYOM1-0.505
CDC14A-0.483
RFTN2-0.478
HEY2-0.474
NFIA-0.471
REST-0.463
RIN2-0.463
TGFBR3-0.46
ACSS3-0.457

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB05047CX717Small Molecule-Illicit|InvestigationalTarget
DB09130CopperSmall Molecule7440-50-8Approved|InvestigationalTarget
DB09301Chondroitin sulfateSmall Molecule24967-93-9Approved|Investigational|NutraceuticalTarget
ID Drug Name Action PubMed
C0252051,10-phenanthroline"1,10-phenanthroline inhibits the reaction [Morphine results in increased expression of BDNF mRNA]"15647486
C0631591-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [decamethrin results in increased expression of BDNF exon]"22079160
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]"22079160
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of BDNF mRNA"19162173
C0238501 alpha,24-dihydroxyvitamin D3"1 alpha,24-dihydroxyvitamin D3 inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]"15781040
C0238501 alpha,24-dihydroxyvitamin D3"1 alpha,24-dihydroxyvitamin D3 promotes the reaction [Pilocarpine results in increased expression of BDNF mRNA]"15781040
C1185591-bromopropane1-bromopropane inhibits the reaction [Bucladesine results in increased expression of BDNF mRNA]19189864
C1185591-bromopropane1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]19189864
C1185591-bromopropane1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]19189864
C1185591-bromopropane1-bromopropane results in decreased expression of BDNF mRNA19189864
C1185591-bromopropane1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]19189864
C1185591-bromopropane1-bromopropane results in decreased expression of BDNF mRNA19189864
C1185591-bromopropane1-bromopropane results in decreased expression of BDNF mRNA23266320
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of BDNF mRNA28329830
C4776942,2',4,4',5-brominated diphenyl ether"2,2',4,4',5-brominated diphenyl ether results in decreased expression of BDNF mRNA"23578391
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BDNF mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"[2,2',4,4'-tetrabromodiphenyl ether co-treated with perfluorooctane sulfonic acid] results in increased expression of BDNF protein"21436126
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF mRNA]"21436126
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF protein]"21436126
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF mRNA]"21436126
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF protein]"21436126
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased methylation of BDNF gene"25533936
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BDNF mRNA"21436126
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BDNF protein"21436126
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased expression of ARC protein]21040763
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased phosphorylation of MAPK1 protein]21040763
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased phosphorylation of MAPK3 protein]21040763
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased expression of BDNF mRNA]16269011
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased phosphorylation of CREB1 protein]14622123
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
C4881852-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide"BDNF gene mutant form results in increased susceptibility to 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide"16945347
C5391422-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one"2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of BDNF protein]"22850435
C5391422-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one"KT 5823 inhibits the reaction [2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of BDNF protein]]"22850435
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased chemical synthesis of Nitric Oxide]17172126
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased phosphorylation of AKT1 protein]19962417
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased phosphorylation of CREB1 protein]19962417
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased expression of PPP1R1B mRNA]17209049
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]17209049
C5707433,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide"3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]"26095976
C5707433,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide"3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]"26095976
C0792153,5-dihydroxyphenylglycine"BDNF protein results in decreased activity of 3,5-dihydroxyphenylglycine"20554863
C0153923-nitropropionic acidBCL2 protein promotes the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid]19428112
C0153923-nitropropionic acidBDNF protein results in decreased susceptibility to 3-nitropropionic acid19428112
C0153923-nitropropionic acidDinitrochlorobenzene inhibits the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid]19428112
C0153923-nitropropionic acidKT 5823 inhibits the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid]19428112
C0087454,4'-bisphenol F"4,4'-bisphenol F results in decreased expression of BDNF mRNA"26186136
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to ARC promoter]]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to FOS promoter]]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to NR4A1 promoter]]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of ARC mRNA]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of ARC protein]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of FOS mRNA]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of NR4A1 mRNA]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased phosphorylation of BRD4 protein]"26301327
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BDNF mRNA"27188386
C0951704-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Zinc results in increased expression of BDNF mRNA]21615740
C0951704-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Zinc results in increased expression of BDNF protein]21615740
C0100244-aminophenylmercuriacetate4-aminophenylmercuriacetate inhibits the reaction [Zinc results in increased expression of BDNF mRNA]21615740
C0100244-aminophenylmercuriacetate4-aminophenylmercuriacetate inhibits the reaction [Zinc results in increased expression of BDNF protein]21615740
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA16337876
C0275764-hydroxy-2-nonenalCREBBP protein inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA]16337876
C0159524-iodo-2,5-dimethoxyphenylisopropylamine"4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of BDNF mRNA"24889602
C0159524-iodo-2,5-dimethoxyphenylisopropylamine"Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of BDNF mRNA]"24889602
C0159524-iodo-2,5-dimethoxyphenylisopropylamine"[Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of BDNF mRNA"24889602
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BDNF mRNA"27188386
C0417156-anilino-5,8-quinolinedione"BDNF protein results in decreased susceptibility to 6-anilino-5,8-quinolinedione"22261313
C1214656-methyl-2-(phenylethynyl)pyridine6-methyl-2-(phenylethynyl)pyridine results in decreased expression of BDNF protein21232601
C1214656-methyl-2-(phenylethynyl)pyridineBDNF protein inhibits the reaction [6-methyl-2-(phenylethynyl)pyridine results in decreased expression of GRM1 protein]21232601
C0408109-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2"9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA"22982731
C0408109-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2"Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]"22982731
D000082AcetaminophenAcetaminophen affects the expression of BDNF mRNA17562736
D000082AcetaminophenAcetaminophen affects the expression of BDNF protein24361869
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of BDNF protein]26138014
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D000171AcroleinAcrolein results in decreased expression of BDNF mRNA16337876
D000171AcroleinCREBBP protein inhibits the reaction [Acrolein results in decreased expression of BDNF mRNA]16337876
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of BDNF gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of BDNF mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of BDNF mRNA26260870
D018350alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acidalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in increased expression of BDNF protein11279263
C010845aluminum chloridealuminum chloride results in decreased expression of BDNF mRNA24973631|2633933
C010845aluminum chloridealuminum chloride results in decreased expression of BDNF protein24973631
C010845aluminum chlorideCaffeine inhibits the reaction [aluminum chloride results in decreased expression of BDNF mRNA]26339337
C067527aluminum maltolatealuminum maltolate inhibits the reaction [BDNF protein results in increased expression of ARC protein]21040763
C067527aluminum maltolatealuminum maltolate inhibits the reaction [BDNF protein results in increased phosphorylation of EIF4EBP1 protein]21040763
C067527aluminum maltolatealuminum maltolate inhibits the reaction [BDNF protein results in increased phosphorylation of EIF4E protein]21040763
C067527aluminum maltolatealuminum maltolate inhibits the reaction [BDNF protein results in increased phosphorylation of MAPK1 protein]21040763
C067527aluminum maltolatealuminum maltolate inhibits the reaction [BDNF protein results in increased phosphorylation of MAPK3 protein]21040763
C067527aluminum maltolatealuminum maltolate results in decreased expression of BDNF mRNA12606298
D000547Amantadine[Fluoxetine co-treated with Amantadine] results in increased expression of BDNF mRNA19211973
D000602Amino Acids, Peptides, and Proteins"BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]"19321768
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
D000643Ammonium ChlorideAmmonium Chloride affects the expression of BDNF mRNA16483693
D003913DextroamphetamineBDNF gene polymorphism affects the susceptibility to Dextroamphetamine16823800
D003913DextroamphetamineDextroamphetamine results in increased expression of BDNF mRNA18681898
D003913DextroamphetamineDextroamphetamine affects the expression of BDNF mRNA19222557
D003913DextroamphetamineDextroamphetamine results in decreased expression of BDNF protein16460767|1743471
D003913DextroamphetamineDextroamphetamine results in increased expression of BDNF mRNA12213320
D003913DextroamphetamineDextroamphetamine results in increased expression of BDNF protein12213320|2737316
D003913DextroamphetamineLithium inhibits the reaction [Dextroamphetamine results in decreased expression of BDNF protein]16460767
D003913DextroamphetamineValproic Acid inhibits the reaction [Dextroamphetamine results in decreased expression of BDNF protein]16460767
D000661AmphetamineBDNF gene mutant form affects the susceptibility to Amphetamine11421589
D000728AndrogensAndrogens affects the expression of BDNF protein17463054
D000928Antidepressive AgentsAntidepressive Agents affects the expression of BDNF mRNA21666748
D047310ApigeninApigenin inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]28389404
D016718Arachidonic AcidArachidonic Acid results in decreased expression of BDNF mRNA16704987
D001151ArsenicArsenic results in decreased expression of BDNF mRNA19654921
D001151ArsenicArsenic results in decreased expression of BDNF mRNA28903487
D001151ArsenicArsenic results in decreased expression of BDNF protein28903487
D001151ArsenicBDNF protein inhibits the reaction [Arsenic results in decreased phosphorylation of NTRK2 protein]28903487
D001151ArsenicBDNF protein inhibits the reaction [Arsenic results in increased cleavage of and results in increased activity of CASP3 protein]28903487
D001151ArsenicBDNF protein inhibits the reaction [Arsenic results in increased cleavage of PARP1 protein]28903487
C006632arsenic trioxidearsenic trioxide results in decreased expression of BDNF protein16711005
C006632arsenic trioxidearsenic trioxide promotes the reaction [Reserpine results in decreased expression of BDNF protein]26114099
C015001arsenitearsenite results in decreased expression of BDNF mRNA23744399|2397400
C015001arsenitearsenite results in increased methylation of BDNF promoter23974009
C015001arseniteTaurine inhibits the reaction [arsenite results in decreased expression of BDNF mRNA]23744399
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of BDNF mRNA"18687144
D001205Ascorbic AcidAscorbic Acid results in increased expression of BDNF mRNA15305145
C030693AshwagandhaAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF mRNA]22096544
C030693AshwagandhaAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF protein]22096544
D001280AtrazineAtrazine results in increased expression of BDNF mRNA18585445
D001374AzacitidineAzacitidine results in decreased methylation of BDNF promoter18184782
D001374AzacitidineAzacitidine results in increased expression of BDNF mRNA18184782
D001374AzacitidineTetrodotoxin inhibits the reaction [Azacitidine results in decreased methylation of BDNF promoter]18184782
D001374AzacitidineTetrodotoxin inhibits the reaction [Azacitidine results in increased expression of BDNF mRNA]18184782
C005177benserazide, levodopa drug combination"[benserazide, levodopa drug combination co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BDNF protein"20014115
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BDNF mRNA22610609
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BDNF protein21467743
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BDNF mRNA21839799
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BDNF mRNA"19150397|2001819
D004958EstradiolEstradiol results in increased expression of BDNF mRNA23373633
D004958EstradiolEstradiol affects the expression of BDNF mRNA28406523
D004958EstradiolEstradiol results in increased expression of BDNF protein15570173
D004958EstradiolProgesterone inhibits the reaction [Estradiol results in increased expression of BDNF protein]15570173
C006780bisphenol Abisphenol A results in decreased expression of BDNF mRNA29275510
C006780bisphenol Abisphenol A affects the expression of BDNF mRNA25385582
C006780bisphenol Abisphenol A inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
C006780bisphenol Abisphenol A results in decreased expression of BDNF mRNA23185968|2353540
C006780bisphenol Abisphenol A results in decreased expression of BDNF protein22484357
C006780bisphenol Abisphenol A results in decreased methylation of BDNF promoter27312807
C006780bisphenol Abisphenol A results in increased methylation of BDNF promoter25385582
C006780bisphenol Abisphenol A affects the expression of BDNF mRNA21786754
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of BDNF mRNA25607892
C006780bisphenol Abisphenol A results in decreased expression of BDNF mRNA25181051|2618613
C006780bisphenol Abisphenol A results in decreased phosphorylation of BDNF protein26827910
D001971BromocriptineBromocriptine results in decreased secretion of BDNF protein12770616
D002038BungarotoxinsBungarotoxins results in increased expression of BDNF mRNA8478687
D002047BuprenorphineBuprenorphine results in decreased expression of BDNF protein24321744
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of BDNF mRNA15336504
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of BDNF mRNA25607892
D002087Butyrates[Butyrates co-treated with Serotonin] results in increased expression of BDNF mRNA19360904
D002104Cadmium[Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of BDNF protein]26138014
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BDNF protein26138014
D019256Cadmium ChlorideCadmium Chloride results in increased methylation of BDNF promoter22457795
D019256Cadmium Chloride[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of BDNF protein23680456
D002110CaffeineCaffeine inhibits the reaction [aluminum chloride results in decreased expression of BDNF mRNA]26339337
D002118Calcium"3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]"26095976
D002118Calcium"3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]"26095976
D002118CalciumBDNF protein results in increased transport of Calcium26095976
D002118CalciumOxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]26095976
D002118CalciumTetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]26095976
D002118Calcium[Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D002118CalciumCalcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D002185CannabidiolCannabidiol results in increased expression of BDNF protein19939866
D002211CapsaicinCapsaicin affects the expression of BDNF protein22150557
D002211Capsaicin[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of BDNF protein]22150557
D002211CapsaicinNaproxen inhibits the reaction [Capsaicin affects the expression of BDNF protein]22150557
D002211CapsaicinSumatriptan inhibits the reaction [Capsaicin affects the expression of BDNF protein]22150557
D002220CarbamazepineCarbamazepine results in increased expression of BDNF mRNA18719996
D002220CarbamazepineCarbamazepine results in increased expression of BDNF protein18719996
D002245Carbon Dioxideifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]24718106
D002245Carbon DioxideLovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]24718106
D002245Carbon Dioxide[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein24718106
D002248Carbon MonoxideCarbon Monoxide results in decreased expression of and results in decreased secretion of BDNF protein27113706
D002248Carbon MonoxideCarbon Monoxide results in decreased expression of BDNF mRNA27113706
D002392CatechinCatechin results in decreased expression of BDNF protein22886603
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein24394491
D020111Chlorodiphenyl (54% Chlorine)Methylphenidate inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D020111Chlorodiphenyl (54% Chlorine)[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D020111Chlorodiphenyl (54% Chlorine)[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [Methylphenidate inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
D020111Chlorodiphenyl (54% Chlorine)[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein24394491
D020111Chlorodiphenyl (54% Chlorine)[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D002737ChloropreneChloroprene results in increased expression of BDNF mRNA23125180
D002746ChlorpromazineBDNF affects the susceptibility to Chlorpromazine18408624
D004390ChlorpyrifosChlorpyrifos affects the expression of BDNF mRNA18502319
D004390ChlorpyrifosChlorpyrifos results in increased expression of BDNF mRNA17893397|2677502
D004390ChlorpyrifosChlorpyrifos results in increased expression of BDNF protein17893397
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BDNF gene20938992
D002809Chondroitin Sulfates[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to BDNF protein15385557
C043561chrysinchrysin inhibits the reaction [Oxidopamine results in decreased expression of BDNF protein]29054324
C043561chrysinchrysin results in increased expression of BDNF protein29054324
D002994ClofibrateClofibrate results in increased expression of BDNF mRNA17585979
C055162clopidogrelclopidogrel results in decreased secretion of BDNF protein21803431
D003024ClozapineClozapine results in decreased expression of BDNF mRNA11488957
D003024ClozapineClozapine results in increased expression of BDNF mRNA12478621
D003024ClozapineClozapine results in increased expression of BDNF protein17442489
D003042CocaineBDNF mRNA results in decreased susceptibility to Cocaine17194538
D003042CocaineBDNF protein results in decreased susceptibility to Cocaine17194538
D003042CocaineBDNF results in increased susceptibility to Cocaine17618281
D003042CocaineCocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]24358339
D003042CocaineCocaine inhibits the reaction [MECP2 protein binds to BDNF promoter]24358339
D003042CocaineCocaine promotes the reaction [BRD4 protein binds to BDNF promoter]26558777
D003042CocaineCocaine results in decreased activity of BDNF protein24358339
D003042CocaineCocaine results in decreased expression of BDNF mRNA18355967
D003042CocaineCocaine results in decreased expression of BDNF protein20554863|2435833
D003042CocaineCocaine results in increased expression of BDNF mRNA12099907|2435833
D003042CocaineFOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]18355967
D003042CocaineHaloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]20554863
D003042Cocaine(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]26558777
D003042Cocaine(+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]26558777
D003042CocaineBDNF mRNA results in decreased susceptibility to Cocaine17194538
D003042Cocaine"BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]"19321768
D003042CocaineBDNF protein results in decreased susceptibility to Cocaine17194538
D003042CocaineBDNF results in decreased susceptibility to Cocaine20810894
D003042CocaineCocaine affects the activity of and affects the expression of BDNF protein17618281
D003042CocaineCocaine affects the expression of BDNF exon20810894
D003042CocaineCocaine affects the expression of BDNF mRNA16423334|1761828
D003042CocaineCocaine affects the expression of BDNF protein14973246|2081089
D003042CocaineCocaine affects the reaction [CREB1 modified form binds to BDNF promoter]20810894
D003042CocaineCocaine affects the reaction [MECP2 protein affects the expression of BDNF protein]20711185
D003042CocaineCocaine affects the reaction [MECP2 protein binds to and results in decreased activity of BDNF promoter]20810894
D003042CocaineCocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]20711185
D003042CocaineCocaine results in increased expression of BDNF protein18311559|2071118
D003042CocaineCocaine results in increased expression of BDNF protein20947769
D003078ColchicineColchicine results in decreased transport of BDNF protein21310905
D005576Colforsin1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]19189864
D005576Colforsin1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]19189864
D005576ColforsinColforsin results in increased expression of BDNF mRNA19189864
D005576ColforsinColforsin results in increased expression of BDNF protein19189864
D005576Colforsin1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]19189864
D005576ColforsinColforsin results in increased expression of BDNF protein19189864
D003300CopperCopper binds to BDNF protein modified form23135810
D003300Copper[Disulfiram binds to Copper] which results in increased expression of BDNF mRNA24690739
D003345Corticosterone"2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of BDNF protein]"22850435
D003345CorticosteroneCorticosterone results in decreased expression of BDNF protein22850435
D003345Corticosterone"KT 5823 inhibits the reaction [2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of BDNF protein]]"22850435
C029036crocincrocin results in increased expression of BDNF mRNA24401376
C029036crocincrocin results in increased expression of BDNF protein24401376
D003471CuprizoneCuprizone results in decreased expression of BDNF mRNA25704630|2605778
D003474CurcuminCurcumin inhibits the reaction [Morphine results in increased expression of BDNF mRNA]19033880
D003474Curcumin[Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of BDNF mRNA22911773
D003474CurcuminCurcumin affects the expression of BDNF protein17617388
D003474Curcumin[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]17827730
D003474CurcuminCurcumin results in increased expression of BDNF protein17022948
D0187506-Cyano-7-nitroquinoxaline-2,3-dione"6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA alternative form]"15183516
D003520CyclophosphamideCyclophosphamide results in increased expression of BDNF mRNA10683293
D016572CyclosporineCyclosporine results in increased methylation of BDNF promoter27989131
C052570cyfluthrincyfluthrin results in increased expression of BDNF mRNA16166269
C017160cypermethrincypermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]11082455
C017160cypermethrincypermethrin results in increased expression of BDNF mRNA16166269
D003609Dactinomycin"Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]"22982731
D003609DactinomycinDactinomycin inhibits the reaction [NEPP11 compound results in increased expression of BDNF mRNA]22982731
D003609DactinomycinDactinomycin results in decreased expression of BDNF mRNA22982731
D003620DantroleneDantrolene inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D003634DDTDDT inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D003634DDT[Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
C010902decabromobiphenyl etherdecabromobiphenyl ether affects the expression of BDNF protein18061678
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of BDNF protein18753049
C017180decamethrindecamethrin results in decreased expression of BDNF mRNA27058123
C017180decamethrindecamethrin results in increased expression of BDNF mRNA24079995
C017180decamethrin"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [decamethrin results in increased expression of BDNF exon]"22079160
C017180decamethrin"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]"22079160
C017180decamethrin"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [decamethrin results in increased expression of BDNF exon]"22079160
C017180decamethrin"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [decamethrin results in increased expression of BDNF mRNA]"22079160
C017180decamethrindecamethrin analog results in increased expression of BDNF mRNA22429507
C017180decamethrindecamethrin results in increased expression of BDNF exon22079160
C017180decamethrindecamethrin results in increased expression of BDNF mRNA12760793|1616626
C017180decamethrindecamethrin results in increased expression of BDNF protein12760793|1616626
C017180decamethringamma-Aminobutyric Acid inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
C017180decamethrinMuscimol inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
C017180decamethrinNicardipine inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]16166269|2207916
C017180decamethrinTacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
C017180decamethrinTacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]22079160
C017180decamethrinTetrodotoxin inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]16166269
C017180decamethrinU 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
C017180decamethrinU 0126 inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]16166269
C017180decamethrinU 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]]22079160
C017180decamethrindecamethrin results in increased expression of BDNF mRNA16310970
C014347decitabinedecitabine results in increased expression of BDNF mRNA16367923
C014347decitabinedecitabine results in increased expression of BDNF mRNA19476549
C107676deguelindeguelin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]17209049
D013759DronabinolDronabinol results in increased expression of BDNF mRNA12657697|2092996
D013759Dronabinolrimonabant inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA]20929960
D013759DronabinolSL 327 inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA]12657697
D013759DronabinolDronabinol results in increased expression of BDNF mRNA15857384
D013759DronabinolDronabinol results in increased expression of BDNF protein15857384
D003871Dermatan Sulfate[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to BDNF protein15385557
D003891DesipramineDesipramine results in increased expression of BDNF mRNA15555640
D003907DexamethasoneDexamethasone results in decreased expression of BDNF mRNA25047013
D003907DexamethasoneDexamethasone results in decreased expression of BDNF protein15215491
D003907DexamethasoneDexamethasone results in decreased expression of BDNF mRNA29111458
D003907DexamethasoneDexamethasone results in decreased expression of BDNF protein29111458
C493686diacetylcurcumin[diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]17827730
C028009diallyl disulfidediallyl disulfide results in decreased expression of BDNF protein23732363
D003975Diazepam[Diazepam co-treated with Pentobarbital] promotes the reaction [Pilocarpine results in increased expression of BDNF mRNA]11259499
D003975DiazepamDiazepam inhibits the reaction [Lithium results in increased expression of BDNF mRNA]9073163
D003975DiazepamDiazepam inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]9073163
D003975DiazepamDiazepam results in increased expression of BDNF protein17442489
D003975Diazepam[Pilocarpine co-treated with Diazepam co-treated with Pentobarbital] results in increased expression of BDNF protein11259499
D003976Diazinon[TLR4 protein mutant form results in increased susceptibility to Diazinon] which results in decreased expression of BDNF mRNA22428454
C016366dibenzothiophenedibenzothiophene results in decreased expression of BDNF mRNA23656968
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BDNF mRNA17361019|2126653
D003993Dibutyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BDNF mRNA21787579
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BDNF protein21787579
D003994Bucladesine1-bromopropane inhibits the reaction [Bucladesine results in increased expression of BDNF mRNA]19189864
D003994BucladesineBucladesine results in increased expression of BDNF mRNA19189864
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of BDNF mRNA28962523
D002945CisplatinCisplatin promotes the reaction [jinfukang results in decreased expression of BDNF mRNA]27392435
D002945Cisplatinjinfukang promotes the reaction [Cisplatin results in decreased expression of BDNF mRNA]27392435
D002945CisplatinCisplatin results in decreased expression of BDNF mRNA22023808
D003633Dichlorodiphenyl Dichloroethylene[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased expression of BDNF mRNA26924002
D016049DidanosineDidanosine results in decreased expression of BDNF mRNA17616550
D016049DidanosineDidanosine results in decreased expression of BDNF mRNA17616550
D004041Dietary FatsDietary Fats results in decreased expression of BDNF protein27417254
D004041Dietary Fats"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate inhibits the reaction [Dietary Fats results in decreased expression of BDNF protein]"27417254
D004041Dietary FatsDietary Fats analog results in decreased expression of BDNF protein28528080
D019422Dietary SucroseDietary Sucrose results in increased expression of BDNF protein20554863
D004051Diethylhexyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
D004054DiethylstilbestrolDiethylstilbestrol inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D004054Diethylstilbestrol[Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of BDNF mRNA17292805|2710353
D002117CalcitriolCalcitriol results in increased expression of BDNF mRNA16002434
D0151165,7-Dihydroxytryptamine"5,7-Dihydroxytryptamine inhibits the reaction [neurotropin affects the expression of BDNF mRNA]"25283187
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BDNF mRNA"22485181
D0198131,2-Dimethylhydrazine"[APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in decreased expression of BDNF mRNA"27840820
C024629dimethyl phthalatedimethyl phthalate affects the expression of BDNF mRNA26924002
D004137DinitrochlorobenzeneDinitrochlorobenzene inhibits the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid]19428112
D004147DioxinsDioxins affects the expression of BDNF mRNA20463971
C061132diphenyldiselenidediphenyldiselenide inhibits the reaction [methylmercuric chloride results in decreased expression of BDNF protein]23954720
D004221Disulfiram[Disulfiram binds to Copper] which results in increased expression of BDNF mRNA24690739
D016291Dizocilpine MaleateDizocilpine Maleate affects the expression of BDNF mRNA8405262
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [Pilocarpine results in increased expression of and results in increased localization of BDNF mRNA]15282290
D016291Dizocilpine MaleateDizocilpine Maleate results in decreased expression of BDNF mRNA8247360
D016291Dizocilpine MaleatePentobarbital inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]8405262
D016291Dizocilpine MaleateScopolamine Hydrobromide inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]8405262
D004281Docosahexaenoic Acids[Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of BDNF mRNA22911773
D004298DopamineBDNF gene mutant form results in increased abundance of Dopamine11421589
C060297echinacosideechinacoside inhibits the reaction [Rotenone results in decreased expression of BDNF protein]23189969
C060297echinacosidestaurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased expression of BDNF protein]]23189969
D004785Environmental Pollutants"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of BDNF mRNA25607892
C062669epicatechin gallate2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
C062669epicatechin gallateARNTL protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
C062669epicatechin gallate[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]29061316
C045651epigallocatechin gallate2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
C045651epigallocatechin gallateARNTL protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
C045651epigallocatechin gallate[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]29061316
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of BDNF protein22886603
C109476epoxiconazole[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
C074283estradiol 3-benzoateestradiol 3-benzoate results in decreased expression of BDNF mRNA21277884
D004967EstrogensEstrogens affects the expression of BDNF mRNA15893308
D000431EthanolEthanol results in increased expression of BDNF24584330
D000431Ethanol[Ethanol co-treated with resveratrol] results in increased expression of BDNF mRNA23770283
D000431EthanolEthanol results in decreased expression of BDNF protein19100286
D000431EthanolEthanol results in increased expression of BDNF mRNA18713641
D000431EthanolEthanol results in increased expression of BDNF protein23770283
D000431Ethanolresveratrol promotes the reaction [Ethanol results in increased expression of BDNF protein]23770283
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of BDNF mRNA23649840
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of BDNF gene16495775
D005047EtoposideEtoposide results in increased expression of BDNF mRNA20573984
D005047EtoposideHIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]20573984
D005054EugenolEugenol results in increased expression of BDNF mRNA15157811
D015025ZearalenoneZearalenone results in decreased expression of BDNF mRNA24412706
C017690fenvaleratefenvalerate results in increased expression of BDNF mRNA16166269
D000068876Fingolimod HydrochlorideFingolimod Hydrochloride results in increased expression of BDNF mRNA24859201
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of BDNF mRNA28329830
D005472FluorouracilFluorouracil results in decreased expression of BDNF protein18702703
D005473FluoxetineFluoxetine results in increased expression of BDNF protein17328894
D005473FluoxetineBDNF gene polymorphism affects the susceptibility to Fluoxetine20016225
D005473FluoxetineBDNF protein results in increased susceptibility to Fluoxetine20016225
D005473FluoxetineBDNF protein mutant form results in decreased susceptibility to Fluoxetine22218094
D005473FluoxetineBDNF protein results in increased susceptibility to Fluoxetine22218094
D005473FluoxetineFluoxetine affects the reaction [sodium arsenate affects the expression of BDNF protein]24952232
D005473FluoxetineFluoxetine results in increased expression of BDNF mRNA15555640|1897399
D005473FluoxetineFluoxetine results in increased expression of BDNF protein21301813|2221809
D005473FluoxetineFluoxetine affects the expression of BDNF mRNA15381288
D005473Fluoxetine[Fluoxetine co-treated with Amantadine] results in increased expression of BDNF mRNA19211973
D005473Fluoxetine[Fluoxetine co-treated with Ketanserin] results in increased expression of BDNF mRNA21627639
D005473FluoxetineFluoxetine results in decreased expression of BDNF mRNA12504921
D005473FluoxetineFluoxetine results in increased expression of BDNF mRNA15456934|1603595
D005473FluoxetineFluoxetine results in increased expression of BDNF mRNA alternative form18301726
D005473FluoxetineFluoxetine results in increased expression of BDNF protein15381288
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BDNF gene20938992
D005520Food Preservatives"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
D005557FormaldehydeFormaldehyde results in increased expression of BDNF mRNA23649840
D005557FormaldehydeFormaldehyde results in increased expression of BDNF mRNA19904815
C069837fullerene C60fullerene C60 results in decreased expression of BDNF mRNA29191454
C069837fullerene C60fullerene C60 results in decreased expression of BDNF protein29191454
D005659Fungicides, Industrial"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
D005690GalactoseGalactose results in decreased expression of BDNF mRNA28974442
D005690GalactoseGalactose results in decreased expression of BDNF protein28974442
D005690Galactoselycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]28974442
D005690Galactoselycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein]28974442
D005707Gallic Acid2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
D005707Gallic AcidARNTL protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
D005707Gallic Acid[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]29061316
C057580gallocatechol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
C057580gallocatecholARNTL protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
C057580gallocatechol[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]29061316
C056507gemcitabinegemcitabine results in decreased expression of BDNF protein20531411
D019833GenisteinGenistein inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
C063170Ginkgo biloba extractGinkgo biloba extract inhibits the reaction [APP protein results in decreased expression of BDNF protein]18001288
C097367ginsenoside Rg3[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
C097367ginsenoside Rg3[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
C097367ginsenoside Rg3[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D005944GlucosamineGlucosamine results in decreased expression of BDNF mRNA17178593
C004312glycidolglycidol results in decreased expression of BDNF mRNA24915197
D006220HaloperidolHaloperidol results in increased expression of BDNF mRNA29182611
D006220HaloperidolHaloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]20554863
D006220HaloperidolHaloperidol results in increased expression of BDNF protein20554863
D006220HaloperidolBDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]15168214
D006220HaloperidolEPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]17805306
D006220HaloperidolHaloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]17442543
D006220HaloperidolHaloperidol results in decreased expression of BDNF mRNA11488957|1239322
D006220HaloperidolHaloperidol results in decreased expression of BDNF protein17805306
D006540Herbicides"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
D003932HeroinHeroin results in decreased expression of BDNF protein17715210
D003932HeroinHeroin inhibits the reaction [CREB1 protein modified form binds to BDNF promoter]25643298
D003932HeroinHeroin results in decreased expression of BDNF mRNA25643298
D012701SerotoninSerotonin analog inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF protein]26408985
D012701Serotonin[Butyrates co-treated with Serotonin] results in increased expression of BDNF mRNA19360904
D012701Serotonin[trichostatin A co-treated with Serotonin] results in increased expression of BDNF mRNA19360904
D012701Serotonin[Valproic Acid co-treated with Serotonin] results in increased expression of BDNF mRNA19360904
C062018HU 211BDNF protein results in decreased activity of HU 21120554863
C062018HU 211BDNF results in decreased susceptibility to HU 21120554863
C062018HU 211lavendustin A inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
C062018HU 211methyl-beta-cyclodextrin inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
C062018HU 211mevastatin inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
C062018HU 211staurosporine aglycone inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
D006854HydrocortisoneHydrocortisone results in increased expression of BDNF protein15531528
D006861Hydrogen Peroxide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
D006861Hydrogen PeroxideARNTL protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]]29061316
D006861Hydrogen Peroxide[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF protein]29061316
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of BDNF protein29061316
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of BDNF mRNA22381256
D006861Hydrogen Peroxide[shogaol co-treated with Hydrogen Peroxide] results in increased expression of BDNF mRNA22381256
D006861Hydrogen Peroxide[shogaol co-treated with Hydrogen Peroxide] results in increased expression of BDNF protein22381256
D006861Hydrogen Peroxideshogaol inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF mRNA]22381256
D006861Hydrogen Peroxide[Hydrogen Peroxide co-treated with BDNF protein] results in increased expression of CHAT protein22381256
D006861Hydrogen Peroxide[Hydrogen Peroxide co-treated with BDNF protein] results in increased expression of SLC5A7 protein22381256
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [BDNF protein results in increased phosphorylation of AKT1 protein]21179406
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [BDNF protein results in increased phosphorylation of MAPK1 protein]21179406
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [BDNF protein results in increased phosphorylation of MAPK3 protein]21179406
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [BDNF protein results in increased phosphorylation of SRC protein]21179406
D006861Hydrogen Peroxidestaurosporine aglycone inhibits the reaction [[Hydrogen Peroxide co-treated with BDNF protein] results in increased expression of CHAT protein]22381256
D006861Hydrogen Peroxidestaurosporine aglycone inhibits the reaction [[Hydrogen Peroxide co-treated with BDNF protein] results in increased expression of SLC5A7 protein]22381256
C010739ifenprodilifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]24718106
D007099ImipramineImipramine results in increased expression of BDNF mRNA15157811
D007099ImipramineImipramine affects the expression of BDNF protein17617388
D007099ImipramineImipramine results in increased expression of BDNF mRNA17950272|8601816
D007099ImipramineRolipram promotes the reaction [Imipramine results in increased expression of BDNF mRNA]8601816
D007306Insecticides"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BDNF mRNA25613284
C544151jinfukangCisplatin promotes the reaction [jinfukang results in decreased expression of BDNF mRNA]27392435
C544151jinfukangjinfukang promotes the reaction [Cisplatin results in decreased expression of BDNF mRNA]27392435
C544151jinfukangjinfukang results in decreased expression of BDNF mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of BDNF mRNA26558777|2675264
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to ARC promoter]]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to FOS promoter]]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to NR4A1 promoter]]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein results in increased expression of ARC mRNA]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein results in increased expression of ARC protein]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein results in increased expression of FOS mRNA]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein results in increased expression of NR4A1 mRNA]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]26558777
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]26558777
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of BDNF mRNA26558777|2664458
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of BDNF protein26558777
D007608Kainic Acid[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]17827730
D007608Kainic Acid[diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]17827730
D007608Kainic AcidKainic Acid results in increased expression of BDNF mRNA11279263|1641125
D007608Kainic AcidKainic Acid results in increased expression of BDNF protein11279263|1616626
D007608Kainic AcidKainic Acid results in increased expression of BDNF mRNA16175575
C468270Kangen-karyuKangen-karyu affects the expression of BDNF mRNA22083044
C468270Kangen-karyuKangen-karyu affects the expression of BDNF protein20637274|2208304
D007649KetamineKetamine inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]8635431
D007650Ketanserin[Fluoxetine co-treated with Ketanserin] results in increased expression of BDNF mRNA21627639
C439304KMUP 1KMUP 1 results in increased expression of BDNF protein19962417
C073601KT 5823"KT 5823 inhibits the reaction [2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of BDNF protein]]"22850435
C073601KT 5823KT 5823 inhibits the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid]19428112
C047781lamotriginelamotrigine results in increased expression of BDNF mRNA18719996
C047781lamotriginelamotrigine results in increased expression of BDNF protein18719996
C062898lavendustin Alavendustin A inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
D007854LeadBDNF protein inhibits the reaction [Lead results in decreased expression of GRIA2 protein]23719929
D007854LeadLead results in decreased expression of BDNF mRNA22345308
D007854LeadLead results in decreased expression of BDNF protein22345308
D007854Lead[Lead results in decreased expression of BDNF protein] which results in decreased phosphorylation of and results in decreased expression of MECP2 protein22345308
C008261lead acetatelead acetate affects the expression of BDNF mRNA alternative form24260418
C008261lead acetatelead acetate results in decreased expression of BDNF mRNA alternative form24260418
C008261lead acetateBDNF protein inhibits the reaction [lead acetate results in decreased expression of SYP protein]20375082
C008261lead acetateBDNF protein inhibits the reaction [lead acetate results in decreased expression of VAMP2 protein]20375082
C008261lead acetateBDNF protein results in decreased susceptibility to lead acetate20375082
C008261lead acetatelead acetate results in decreased expression of BDNF protein20375082|2314675
C008261lead acetatelead acetate results in decreased secretion of BDNF protein20375082
C008261lead acetate[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of BDNF protein23680456
D001556LindaneLindane results in increased expression of BDNF protein11279263
D008044Linuron[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of BDNF mRNA18047562
D008070LipopolysaccharidesSimvastatin promotes the reaction [Lipopolysaccharides results in increased expression of BDNF mRNA]18047562
D008094LithiumBDNF gene polymorphism affects the susceptibility to Lithium19018715
D008094LithiumBDNF protein results in increased susceptibility to Lithium19018715
D008094LithiumDiazepam inhibits the reaction [Lithium results in increased expression of BDNF mRNA]9073163
D008094LithiumLithium inhibits the reaction [Dextroamphetamine results in decreased expression of BDNF protein]16460767
D008094LithiumLithium inhibits the reaction [Ouabain results in decreased expression of BDNF protein]19954800
D008094LithiumLithium results in decreased expression of BDNF mRNA21220416
D008094LithiumLithium results in increased expression of BDNF mRNA9073163
D008094LithiumLithium results in increased expression of BDNF protein17442489
D008148LovastatinLovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]24718106
C015329lycopenelycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]28974442
C015329lycopenelycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein]28974442
D008344Maneb[Maneb co-treated with Paraquat] results in decreased expression of BDNF mRNA23017109
D008344Maneb[Paraquat co-treated with Maneb] results in decreased expression of BDNF mRNA27460631
D008344Maneb[Paraquat co-treated with Maneb] results in decreased expression of BDNF protein27460631
D008345ManganeseManganese results in decreased expression of BDNF protein25099302
D008345ManganeseManganese results in decreased expression of BDNF protein25099302
D008345Manganese[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]17827730
D008345Manganese[diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]17827730
D008345ManganeseManganese results in decreased expression of BDNF mRNA29205667
D008345ManganeseManganese results in decreased expression of BDNF protein25099302|2920566
C025340manganese chloridemanganese chloride results in decreased expression of BDNF mRNA25698507
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BDNF mRNA"27188386
D008627Mercuric Chloride[Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of BDNF mRNA21084432
D008628MercuryBDNF polymorphism affects the susceptibility to Mercury16301096
D008628MercuryMercury results in decreased expression of BDNF mRNA19937285
D008694MethamphetamineBDNF gene polymorphism affects the susceptibility to Methamphetamine19462300
D008694MethamphetamineBDNF gene SNP results in increased susceptibility to Methamphetamine20736000
D008694MethamphetamineMethamphetamine results in increased expression of BDNF protein16039058
D008694MethamphetamineBDNF protein affects the susceptibility to Methamphetamine15050682
D008694MethamphetamineMethamphetamine results in increased expression of BDNF protein27373168
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BDNF gene20938992
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate inhibits the reaction [Dietary Fats results in decreased expression of BDNF protein]"27417254
C108732methyl-beta-cyclodextrinmethyl-beta-cyclodextrin inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
C054634methyllycaconitinemethyllycaconitine inhibits the reaction [Nicotine results in increased secretion of BDNF protein]16790237
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of BDNF mRNA28001369
C004925methylmercuric chloridediphenyldiselenide inhibits the reaction [methylmercuric chloride results in decreased expression of BDNF protein]23954720
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of BDNF protein23954720
D008767Methylmercury CompoundsMethylmercury Compounds affects the expression of BDNF protein20631062
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of BDNF mRNA26558463
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of BDNF protein28267559
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of BDNF mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BDNF mRNA"19285098
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of BDNF protein"27373168
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased expression of BDNF mRNA15120970
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of BDNF mRNA28688903
D008743Methyl ParathionMethyl Parathion results in increased expression of BDNF mRNA17893397
D008743Methyl ParathionMethyl Parathion results in increased expression of BDNF protein17893397
D008774MethylphenidateMethylphenidate inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D008774Methylphenidate[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [Methylphenidate inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
D008774MethylphenidateMethylphenidate results in decreased expression of BDNF mRNA22470460
D008774MethylphenidateMethylphenidate affects the expression of BDNF mRNA19222557
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of BDNF mRNA25234470
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[benserazide, levodopa drug combination co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BDNF protein"20014115
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA"23747572
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein"23747572|2499181
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BDNF mRNA"15329391
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"salvianolic acid B inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein]"24991814
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]"23747572
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein]"23747572
C012258mevastatinmevastatin inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
D015735MifepristoneMifepristone results in decreased expression of BDNF protein17464718
C517284monomethyl phthalatemonomethyl phthalate affects the expression of BDNF mRNA26924002
D009020MorphineBDNF protein inhibits the reaction [NR4A2 protein affects the susceptibility to Morphine]25643298
D009020MorphineCurcumin inhibits the reaction [Morphine results in increased expression of BDNF mRNA]19033880
D009020MorphineMorphine results in decreased expression of BDNF mRNA25643298
D009020MorphineMorphine results in increased expression of BDNF mRNA19033880
D009020MorphineMorphine inhibits the reaction [CREB1 protein modified form binds to BDNF promoter]25643298
D009020MorphineMorphine inhibits the reaction [NR4A2 protein binds to BDNF promoter]25643298
D009020MorphineMorphine inhibits the reaction [RING1 protein alternative form binds to BDNF promoter]25643298
D009020MorphineMorphine promotes the reaction [CREB1 protein binds to BDNF promoter]25643298
D009020MorphineMorphine promotes the reaction [EZH2 protein binds to BDNF promoter]25643298
D009020MorphineMorphine promotes the reaction [ING2 protein binds to BDNF promoter]25643298
D009020MorphineMorphine promotes the reaction [KMT2A protein binds to BDNF promoter]25643298
D009020MorphineMorphine promotes the reaction [SIN3A protein binds to BDNF promoter]25643298
D009020MorphineMorphine promotes the reaction [SUZ12 protein binds to BDNF promoter]25643298
D009020MorphineMorphine results in decreased expression of BDNF mRNA25643298
D009020MorphineMorphine results in decreased expression of BDNF mRNA alternative form25643298
D009020Morphine"1,10-phenanthroline inhibits the reaction [Morphine results in increased expression of BDNF mRNA]"15647486
D009020Morphine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
D009020MorphineGenistein inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
D009020MorphineMorphine results in increased expression of BDNF mRNA15647486
D009020MorphineNaloxone inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
D009020Morphinewortmannin inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
D009118MuscimolMuscimol inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
D009151Mustard GasMustard Gas results in increased expression of BDNF mRNA15674844
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FGF2 protein results in increased expression of BDNF mRNA]16269011
D009270NaloxoneNaloxone inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of BDNF mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of BDNF mRNA"25554681
D009288Naproxen[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of BDNF protein]22150557
D009288NaproxenNaproxen inhibits the reaction [Capsaicin affects the expression of BDNF protein]22150557
C424427NEPP11 compoundDactinomycin inhibits the reaction [NEPP11 compound results in increased expression of BDNF mRNA]22982731
C424427NEPP11 compoundNEPP11 compound results in increased expression of BDNF mRNA22982731
C010491neurotropin"5,7-Dihydroxytryptamine inhibits the reaction [neurotropin affects the expression of BDNF mRNA]"25283187
C010491neurotropinneurotropin affects the expression of BDNF mRNA25283187
D009525NiacinNiacin results in increased expression of BDNF protein20671245
D009529NicardipineNicardipine inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]16166269|2207916
D009532NickelNickel results in decreased expression of BDNF mRNA25583101
D009538NicotineBDNF gene polymorphism affects the susceptibility to Nicotine17186223
D009538Nicotinemethyllycaconitine inhibits the reaction [Nicotine results in increased secretion of BDNF protein]16790237
D009538NicotineNicotine results in increased secretion of BDNF protein16790237
D009538NicotineNicotine affects the expression of BDNF mRNA20426880
D009538NicotineNicotine results in increased expression of BDNF mRNA9503263|9832142
D009543Nifedipine"Nifedipine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BDNF protein]"11279263
D009569Nitric Oxide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [BDNF protein results in increased chemical synthesis of Nitric Oxide]17172126
D009569Nitric OxideBDNF protein results in increased chemical synthesis of Nitric Oxide17172126
D009569Nitric OxideBDNF protein results in decreased susceptibility to Nitric Oxide9870933
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in decreased expression of BDNF mRNA17616710
C025589ochratoxin Aochratoxin A results in increased expression of BDNF mRNA27346841
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of BDNF mRNA25607892
D016627Oxidopaminechrysin inhibits the reaction [Oxidopamine results in decreased expression of BDNF protein]29054324
D016627OxidopamineOxidopamine results in decreased expression of BDNF protein29054324
C076029olanzapineolanzapine results in increased expression of BDNF mRNA29182611
C076029olanzapineolanzapine results in increased expression of BDNF protein29182611
C076029olanzapineolanzapine results in increased expression of BDNF mRNA12478621
C076029olanzapineolanzapine results in increased expression of BDNF protein17442489
D010100Oxygen"3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]"26095976
D010100Oxygen"3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]"26095976
D010100OxygenOxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]26095976
D010100OxygenTetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]26095976
D010100Oxygen1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D010100OxygenAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D010100Oxygen[Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D010100OxygenCalcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D010100OxygenDantrolene inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D010100OxygenOxygen deficiency results in increased secretion of and results in increased expression of BDNF protein16553631
D010100Oxygentetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D010100Oxygenifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]24718106
D010100OxygenLovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]24718106
D010100Oxygen[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein24718106
D010100OxygenOxygen deficiency results in decreased expression of BDNF mRNA18541227
D010100OxygenOxygen deficiency results in decreased secretion of BDNF protein18541227
D010100Oxygenpanaxydol inhibits the reaction [Oxygen deficiency results in decreased expression of BDNF mRNA]18541227
D010100Oxygenpanaxydol inhibits the reaction [Oxygen deficiency results in decreased secretion of BDNF protein]18541227
D010126Ozone[Ozone co-treated with Vehicle Emissions] results in increased expression of BDNF mRNA23358141
D010126OzoneOzone results in increased expression of BDNF mRNA17095637
D010126OzoneOzone results in increased expression of BDNF mRNA16716893
D000068882Paliperidone PalmitatePaliperidone Palmitate results in increased expression of BDNF mRNA21220416
C055778panaxydolpanaxydol inhibits the reaction [Oxygen deficiency results in decreased expression of BDNF mRNA]18541227
C055778panaxydolpanaxydol inhibits the reaction [Oxygen deficiency results in decreased secretion of BDNF protein]18541227
C055778panaxydolpanaxydol results in increased expression of and results in increased secretion of BDNF protein18805406
D010208PapaverinePapaverine results in increased expression of BDNF mRNA8601816
D010242ParaldehydeParaldehyde promotes the reaction [Pilocarpine results in increased expression of BDNF mRNA]11259499
D010269Paraquat[Maneb co-treated with Paraquat] results in decreased expression of BDNF mRNA23017109
D010269Paraquat[Paraquat co-treated with Maneb] results in decreased expression of BDNF mRNA27460631
D010269Paraquat[Paraquat co-treated with Maneb] results in decreased expression of BDNF protein27460631
D017374ParoxetineParoxetine results in increased expression of BDNF mRNA21301813
D017374ParoxetineParoxetine results in increased expression of BDNF protein21301813
D052638Particulate MatterParticulate Matter results in decreased expression of BDNF mRNA25816123
D052638Particulate MatterParticulate Matter results in increased expression of BDNF mRNA24769257
D052638Particulate MatterParticulate Matter results in increased expression of BDNF mRNA21663545
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of BDNF mRNA22024335
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of BDNF protein22024335
D010424Pentobarbital[Diazepam co-treated with Pentobarbital] promotes the reaction [Pilocarpine results in increased expression of BDNF mRNA]11259499
D010424PentobarbitalPentobarbital inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]8405262
D010424PentobarbitalPentobarbital results in decreased expression of BDNF mRNA8247360
D010424Pentobarbital[Pilocarpine co-treated with Diazepam co-treated with Pentobarbital] results in increased expression of BDNF protein11259499
D010433PentylenetetrazolePentylenetetrazole results in increased expression of BDNF mRNA11279263
D010433PentylenetetrazolePentylenetetrazole results in increased expression of BDNF protein11279263
C584865perfluorononanoic acid"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in increased expression of BDNF mRNA23602845
C076994perfluorooctane sulfonic acid"[2,2',4,4'-tetrabromodiphenyl ether co-treated with perfluorooctane sulfonic acid] results in increased expression of BDNF protein"21436126
C076994perfluorooctane sulfonic acid"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF mRNA]"21436126
C076994perfluorooctane sulfonic acid"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF protein]"21436126
C076994perfluorooctane sulfonic acid"2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF mRNA]"21436126
C076994perfluorooctane sulfonic acid"2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF protein]"21436126
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of BDNF protein25524167
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of BDNF mRNA21436126|2552416
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of BDNF protein21436126
D026023Permethrin[Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D026023PermethrinPermethrin inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D026023PermethrinPermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]11082455
D026023PermethrinPermethrin results in decreased expression of BDNF mRNA12111003
D026023PermethrinPermethrin results in increased expression of BDNF mRNA19017407
D030421Peroxynitrous AcidBDNF protein promotes the reaction [Peroxynitrous Acid results in increased phosphorylation of AKT1 protein]17302912
D030421Peroxynitrous AcidPeroxynitrous Acid promotes the reaction [BDNF protein results in increased phosphorylation of AKT1 protein]17302912
C000593032PGW5 compoundPGW5 compound affects the expression of BDNF protein24389121
D010634PhenobarbitalPhenobarbital affects the expression of BDNF mRNA23091169
D010656PhenylephrinePhenylephrine results in increased expression of BDNF mRNA18158353
D016226Phosphorus, Dietary"Phosphorus, Dietary affects the expression of BDNF mRNA"17651324
D064209Phytochemicals"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
D010852PicrotoxinPicrotoxin results in decreased methylation of BDNF promoter18184782
D010852PicrotoxinPicrotoxin results in increased expression of BDNF mRNA18184782
D010852PicrotoxinPicrotoxin results in increased expression of BDNF protein11279263
D010862PilocarpinePilocarpine results in increased expression of BDNF protein modified form19397936
D010862Pilocarpine"1 alpha,24-dihydroxyvitamin D3 inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]"15781040
D010862Pilocarpine"1 alpha,24-dihydroxyvitamin D3 promotes the reaction [Pilocarpine results in increased expression of BDNF mRNA]"15781040
D010862Pilocarpine"6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA alternative form]"15183516
D010862PilocarpineBDNF inhibits the reaction [Pilocarpine results in increased expression of IL1B protein]21087489
D010862Pilocarpine[Diazepam co-treated with Pentobarbital] promotes the reaction [Pilocarpine results in increased expression of BDNF mRNA]11259499
D010862PilocarpineDiazepam inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]9073163
D010862PilocarpineDizocilpine Maleate inhibits the reaction [Pilocarpine results in increased expression of and results in increased localization of BDNF mRNA]15282290
D010862PilocarpineKetamine inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]8635431
D010862PilocarpineParaldehyde promotes the reaction [Pilocarpine results in increased expression of BDNF mRNA]11259499
D010862Pilocarpine[Pilocarpine co-treated with Diazepam co-treated with Pentobarbital] results in increased expression of BDNF protein11259499
D010862PilocarpinePilocarpine promotes the reaction [BDNF protein results in decreased expression of NTRK2 protein]19686240
D010862PilocarpinePilocarpine results in decreased expression of BDNF protein11259499
D010862PilocarpinePilocarpine results in increased expression of and results in increased localization of BDNF mRNA15282290
D010862PilocarpinePilocarpine results in increased expression of and results in increased localization of BDNF protein15282290
D010862PilocarpinePilocarpine results in increased expression of BDNF exon15183516
D010862PilocarpinePilocarpine results in increased expression of BDNF mRNA11259499|1465632
D010862PilocarpinePilocarpine results in increased expression of BDNF mRNA alternative form15183516
D010862PilocarpinePilocarpine results in increased expression of BDNF protein12231234|8821376
D010862PilocarpineScopolamine Hydrobromide inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]8635431
D010936Plant Extracts[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D010936Plant Extracts[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
D010936Plant Extracts[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D010936Plant ExtractsPlant Extracts inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF mRNA]26434561
D028321Plant PreparationsPlant Preparations results in increased expression of BDNF protein15500971
D010968Plasticizers"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
C531249Poly(amidoamine)Poly(amidoamine) analog results in increased expression of BDNF mRNA24813635
D011070Poly I-C"Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of BDNF mRNA]"24889602
D011070Poly I-C"[Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of BDNF mRNA"24889602
D011188Potassiumbisphenol A inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D011188PotassiumDDT inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D011188PotassiumDiethylstilbestrol inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D011188Potassium[Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D011188PotassiumPermethrin inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D011188PotassiumPyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D011188PotassiumPotassium results in increased expression of BDNF8978711
D011188Potassium[Potassium results in increased expression of BDNF] which results in increased expression of NTF38978711
D011188PotassiumPotassium affects the susceptibility to BDNF protein8978711
D011189Potassium ChlorideBDNF promoter modified form affects the reaction [Potassium Chloride results in increased expression of BDNF mRNA]14593183|1459318
D011189Potassium ChloridePotassium Chloride inhibits the reaction [HDAC1 protein binds to BDNF promoter]14593183
D011189Potassium ChloridePotassium Chloride inhibits the reaction [MECP2 protein binds to BDNF promoter]14593183
D011189Potassium ChloridePotassium Chloride inhibits the reaction [SIN3A protein binds to BDNF promoter]14593183
D011189Potassium ChloridePotassium Chloride promotes the reaction [CREB1 protein binds to BDNF promoter]14593183
D011189Potassium ChloridePotassium Chloride results in decreased methylation of BDNF promoter14593183
D011189Potassium ChloridePotassium Chloride results in increased expression of BDNF mRNA14593183
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of BDNF mRNA22714537
C045362prochlorazprochloraz results in increased expression of BDNF mRNA21470553
C045362prochloraz[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
C035988procymidone[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
D011374ProgesteroneProgesterone results in decreased expression of BDNF mRNA18070364
D011374ProgesteroneProgesterone affects the localization of BDNF protein17052708
D011374ProgesteroneProgesterone inhibits the reaction [VPS54 gene mutant form results in decreased expression of BDNF mRNA]17052708
D011374ProgesteroneProgesterone results in increased expression of BDNF mRNA17549730|2315723
D011374ProgesteroneProgesterone results in increased expression of BDNF protein17549730
D011374ProgesteroneProgesterone inhibits the reaction [Estradiol results in increased expression of BDNF protein]15570173
C005556propionaldehydepropionaldehyde results in increased expression of BDNF mRNA26079696
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [BDNF protein results in increased expression of SOD2 protein]22261313
D011722PyrethrinsPyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA]15527870
D0014983-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [decamethrin results in increased expression of BDNF exon]"22079160
D0014983-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [decamethrin results in increased expression of BDNF mRNA]"22079160
D0014983-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BDNF mRNA"11279263
D0014983-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BDNF protein"11279263
D0014983-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester"Nifedipine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BDNF protein]"11279263
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein]22261313
D011765PyruvaldehydePyruvaldehyde results in increased expression of BDNF protein25933243
D011765Pyruvaldehydesulforafan promotes the reaction [Pyruvaldehyde results in increased expression of BDNF protein]25933243
D000069348Quetiapine FumarateQuetiapine Fumarate results in increased expression of BDNF protein17442489
C502851quinocetonequinocetone results in decreased expression of BDNF mRNA27046791
D017378Quinolinic AcidQuinolinic Acid results in increased expression of BDNF mRNA15698628
D012110Reserpinearsenic trioxide promotes the reaction [Reserpine results in decreased expression of BDNF protein]26114099
D012110ReserpineReserpine results in decreased expression of BDNF protein26114099
C059514resveratrolresveratrol results in decreased expression of BDNF protein23105098
C059514resveratrolresveratrol results in increased expression of BDNF mRNA24125781
C059514resveratrolresveratrol results in increased expression of BDNF protein24125781
C059514resveratrol[Ethanol co-treated with resveratrol] results in increased expression of BDNF mRNA23770283
C059514resveratrolresveratrol affects the expression of BDNF23850968
C059514resveratrolresveratrol promotes the reaction [Ethanol results in increased expression of BDNF protein]23770283
C089032rimonabantrimonabant inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA]20929960
D018967RisperidoneBDNF gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]19997080
D018967RisperidoneRisperidone inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]17442543
D018967RisperidoneRisperidone results in decreased expression of BDNF mRNA12393228
D016713RitanserinRitanserin results in increased expression of BDNF mRNA12393228
D020889RolipramRolipram promotes the reaction [Imipramine results in increased expression of BDNF mRNA]8601816
D020889RolipramRolipram results in increased expression of BDNF mRNA8601816
C104586roscovitineroscovitine inhibits the reaction [BDNF protein results in increased expression of PPP1R1B mRNA]17209049
C104586roscovitineroscovitine inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]17209049
D012402RotenoneBDNF protein affects the reaction [PITX3 protein results in decreased susceptibility to Rotenone]18646205
D012402RotenoneApigenin inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]28389404
D012402Rotenoneechinacoside inhibits the reaction [Rotenone results in decreased expression of BDNF protein]23189969
D012402RotenoneHaloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]17442543
D012402RotenoneRisperidone inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]17442543
D012402RotenoneRotenone results in decreased expression of BDNF mRNA17442543|2838940
D012402RotenoneRotenone results in decreased expression of BDNF protein23189969|2544667
D012402Rotenonesaxagliptin inhibits the reaction [Rotenone results in decreased expression of BDNF protein]25446674
D012402Rotenonestaurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased expression of BDNF protein]]23189969
D012402RotenoneBDNF protein results in decreased susceptibility to Rotenone18646205
C084711S 20098S 20098 results in increased expression of BDNF mRNA19775499
C084711S 20098S 20098 results in increased expression of BDNF protein22160164
C036617salsolinolsalsolinol results in decreased expression of BDNF protein23261589
C076944salvianolic acid B"salvianolic acid B inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein]"24991814
C076944salvianolic acid Bsalvianolic acid B results in increased expression of BDNF protein24991814
C502994saxagliptinsaxagliptin inhibits the reaction [Rotenone results in decreased expression of BDNF protein]25446674
D012601Scopolamine HydrobromideAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF mRNA]22096544
D012601Scopolamine HydrobromideAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF protein]22096544
D012601Scopolamine HydrobromidePlant Extracts inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF mRNA]26434561
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in decreased expression of BDNF mRNA22096544|2643456
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in decreased expression of BDNF protein22096544|2640898
D012601Scopolamine HydrobromideSerotonin analog inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF protein]26408985
D012601Scopolamine HydrobromideTacrine inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF protein]26408985
D012601Scopolamine HydrobromideScopolamine Hydrobromide inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]8405262
D012601Scopolamine HydrobromideScopolamine Hydrobromide inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]8635431
D020280SertralineSertraline results in increased expression of BDNF protein18403212
C040115shogaol[shogaol co-treated with Hydrogen Peroxide] results in increased expression of BDNF mRNA22381256
C040115shogaol[shogaol co-treated with Hydrogen Peroxide] results in increased expression of BDNF protein22381256
C040115shogaolshogaol inhibits the reaction [Hydrogen Peroxide results in decreased expression of BDNF mRNA]22381256
C040115shogaol[shogaol results in increased expression of BDNF protein] which results in increased expression of CHAT protein22381256
C040115shogaol[shogaol results in increased expression of BDNF protein] which results in increased expression of SLC5A7 protein22381256
D012834SilverSilver results in increased expression of BDNF mRNA26551752
D019821SimvastatinSimvastatin promotes the reaction [Lipopolysaccharides results in increased expression of BDNF mRNA]18047562
D019821SimvastatinSimvastatin results in increased expression of BDNF20851742
D020123SirolimusSirolimus inhibits the reaction [BDNF protein results in increased expression of PPP1R1B mRNA]17209049
D020123SirolimusSirolimus inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]17209049
C424127SL 327BDNF gene mutant form results in increased susceptibility to SL 32716945347
C424127SL 327SL 327 inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA]12657697
D012906SmokeSmoke affects the expression of BDNF protein20631062
C009277sodium arsenateFluoxetine affects the reaction [sodium arsenate affects the expression of BDNF protein]24952232
C009277sodium arsenatesodium arsenate affects the expression of BDNF protein24952232
C017947sodium arsenitesodium arsenite results in increased expression of BDNF mRNA12760830
C017947sodium arsenite[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of BDNF protein23680456
D012999SomanSoman results in increased expression of BDNF mRNA19281266|2620508
C049985staurosporine aglycone[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [Methylphenidate inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
C049985staurosporine aglycone[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [BDNF protein results in increased phosphorylation of AKT1 protein]19962417
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [BDNF protein results in increased phosphorylation of CREB1 protein]19962417
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [BDNF protein results in decreased activity of HU 211]20554863
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased expression of BDNF protein]]23189969
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [[Hydrogen Peroxide co-treated with BDNF protein] results in increased expression of CHAT protein]22381256
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [[Hydrogen Peroxide co-treated with BDNF protein] results in increased expression of SLC5A7 protein]22381256
D010042OuabainLithium inhibits the reaction [Ouabain results in decreased expression of BDNF protein]19954800
D010042OuabainOuabain results in decreased expression of BDNF protein19954800
C016766sulforafansulforafan promotes the reaction [Pyruvaldehyde results in increased expression of BDNF protein]25933243
C016766sulforafansulforafan results in increased expression of BDNF protein25933243
D018170Sumatriptan[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of BDNF protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [Capsaicin affects the expression of BDNF protein]22150557
D013473Sunscreening Agents"[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluorononanoic acid] which results in decreased expression of BDNF protein"25588985
D013619TacrineTacrine inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of BDNF protein]26408985
D016559TacrolimusTacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
D016559TacrolimusTacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]22079160
D016559TacrolimusU 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]]22079160
C061133tamibarotene[tamibarotene co-treated with BDNF] results in increased expression of NTRK219182380
C061133tamibaroteneBDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK1 protein]19457078
C061133tamibaroteneBDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK3 protein]19457078
C061133tamibaroteneBDNF affects the reaction [tamibarotene results in increased phosphorylation of NTRK2 protein]19457078
C061133tamibarotenetamibarotene results in increased expression of BDNF mRNA19457078
D013629TamoxifenTamoxifen affects the expression of BDNF mRNA14699072
D013654TaurineTaurine inhibits the reaction [arsenite results in decreased expression of BDNF mRNA]23744399
C084178telmisartan"telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]"23747572
C084178telmisartan"telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein]"23747572
D013729Terpenes[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D013729Terpenes[staurosporine aglycone binds to and results in decreased activity of NTRK2 protein] inhibits the reaction [[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]]24394491
D013729Terpenes[Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of BDNF protein]24394491
D043343Testosterone PropionateTestosterone Propionate results in increased expression of BDNF mRNA19427307
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BDNF mRNA16443690
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to BDNF promoter]19654925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BDNF mRNA15328365
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of BDNF mRNA12606293
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BDNF mRNA25613284
C050950tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complextetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]16553631
D013779Tetrodotoxin"3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]"26095976
D013779TetrodotoxinTetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]26095976
D013779TetrodotoxinTetrodotoxin inhibits the reaction [Azacitidine results in decreased methylation of BDNF promoter]18184782
D013779TetrodotoxinTetrodotoxin inhibits the reaction [Azacitidine results in increased expression of BDNF mRNA]18184782
D013779TetrodotoxinTetrodotoxin inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]16166269
D013779TetrodotoxinTetrodotoxin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]16166269
C022616thiazolyl blueBDNF protein results in increased reduction of thiazolyl blue12548706
D013893ThiramThiram results in increased expression of BDNF mRNA20530235
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of BDNF mRNA28111298
D014050TolueneToluene results in decreased expression of BDNF mRNA17481687
D014050TolueneToluene results in increased expression of BDNF mRNA17870172|1993271
C483909torcetrapibtorcetrapib results in increased expression of BDNF mRNA23228038
D014191TranylcypromineTranylcypromine results in increased expression of BDNF mRNA8601816
D014212TretinoinTretinoin results in decreased expression of BDNF mRNA20530235
D014212Tretinoin[BDNF protein co-treated with Tretinoin] results in increased expression of APP protein16150056
D014212TretinoinBDNF protein inhibits the reaction [Tretinoin results in increased N-linked glycosylation of APLP1 protein]16150056
D014212TretinoinTretinoin results in increased expression of BDNF mRNA21934132
D014212Tretinoin[Tretinoin co-treated with BDNF protein co-treated with NTF3 protein] results in decreased expression of MAP2 protein16646665
D014212TretinoinTretinoin results in decreased expression of BDNF protein17026715
C034613triacsin Ctriacsin C results in decreased expression of BDNF mRNA16704987
D014229Triazolam[Triazolam co-treated with zolpidem] results in decreased expression of BDNF protein24367698
C012584triazophostriazophos results in decreased expression of BDNF mRNA23949197
C012584triazophostriazophos results in decreased expression of BDNF protein23949197
D014241Trichloroethylene[Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of BDNF mRNA21084432
D014241TrichloroethyleneTrichloroethylene results in decreased expression of BDNF mRNA22421312
C012589trichostatin Atrichostatin A results in decreased expression of BDNF mRNA24935251
C012589trichostatin Atrichostatin A results in increased expression of BDNF mRNA24935251
C012589trichostatin Atrichostatin A inhibits the reaction [BDNF protein results in increased expression of NAB2 protein]24204683
C012589trichostatin Atrichostatin A inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]24204683
C012589trichostatin A[trichostatin A co-treated with Serotonin] results in increased expression of BDNF mRNA19360904
C012589trichostatin Atrichostatin A results in increased expression of BDNF mRNA19476549
C068051tripchlorolidetripchlorolide results in increased expression of BDNF mRNA12504865
C113580U 0126U 0126 inhibits the reaction [FGF2 protein results in increased expression of BDNF mRNA]16269011
C113580U 0126Tacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]22079160
C113580U 0126U 0126 inhibits the reaction [BDNF protein results in increased phosphorylation of CREB1 protein]14622123
C113580U 0126U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]22079160
C113580U 0126U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF mRNA]16166269
C113580U 0126U 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]]22079160
C022884undecaneundecane results in decreased expression of BDNF protein17337753
D014635Valproic AcidValproic Acid affects the expression of BDNF mRNA25979313
D014635Valproic AcidValproic Acid results in decreased methylation of BDNF gene29154799
D014635Valproic AcidValproic Acid results in increased expression of BDNF mRNA23179753|2438349
D014635Valproic Acid[Valproic Acid co-treated with BDNF protein] results in decreased expression of BCL11B protein24204683
D014635Valproic AcidValproic Acid inhibits the reaction [BDNF protein results in increased expression of NAB2 protein]24204683
D014635Valproic AcidValproic Acid inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]24204683
D014635Valproic AcidValproic Acid results in decreased expression of BDNF mRNA20603192
D014635Valproic AcidValproic Acid results in increased expression of BDNF mRNA10689198
D014635Valproic Acid[Valproic Acid co-treated with Serotonin] results in increased expression of BDNF mRNA19360904
D014635Valproic AcidValproic Acid inhibits the reaction [Dextroamphetamine results in decreased expression of BDNF protein]16460767
D014635Valproic AcidValproic Acid results in decreased expression of BDNF mRNA23665938
D014635Valproic AcidValproic Acid results in increased expression of BDNF protein17442489
D001335Vehicle Emissions[Ozone co-treated with Vehicle Emissions] results in increased expression of BDNF mRNA23358141
D001335Vehicle EmissionsVehicle Emissions affects the methylation of BDNF gene25560391
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of BDNF mRNA22906174
D001335Vehicle EmissionsVehicle Emissions results in increased expression of BDNF mRNA19629445|2166354
D000069470Venlafaxine HydrochlorideVenlafaxine Hydrochloride results in increased expression of BDNF mRNA17950272
D014701Veratridinecypermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]11082455
D014701VeratridinePermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]11082455
D014701VeratridineVeratridine results in increased expression of BDNF mRNA11082455
D014701VeratridineTetrodotoxin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]16166269
D014701VeratridineVeratridine results in increased expression of BDNF mRNA16166269
C025643vinclozolin[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA25607892
C025643vinclozolinvinclozolin affects the expression of BDNF mRNA19015723
C029297vinylidene chloridevinylidene chloride results in decreased expression of BDNF mRNA26682919
C009680VXVX results in increased expression of BDNF mRNA22240983
C009680VXVX results in increased expression of BDNF protein22240983
C009687wortmanninwortmannin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]17209049
C009687wortmanninwortmannin inhibits the reaction [Morphine results in increased expression of BDNF mRNA]15647486
D014978XenonXenon results in increased expression of BDNF protein16034370
D015032Zinc4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Zinc results in increased expression of BDNF mRNA]21615740
D015032Zinc4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Zinc results in increased expression of BDNF protein]21615740
D015032Zinc4-aminophenylmercuriacetate inhibits the reaction [Zinc results in increased expression of BDNF mRNA]21615740
D015032Zinc4-aminophenylmercuriacetate inhibits the reaction [Zinc results in increased expression of BDNF protein]21615740
D015032ZincBDNF protein affects the reaction [Zinc results in increased expression of PLAT mRNA]21615740
D015032ZincBDNF protein affects the reaction [Zinc results in increased expression of PLAT protein]21615740
D015032ZincBDNF protein affects the reaction [Zinc results in increased expression of PLG mRNA]21615740
D015032ZincBDNF protein affects the reaction [Zinc results in increased expression of PLG protein]21615740
D015032ZincZinc deficiency results in increased expression of BDNF protein20101602
D015032ZincZinc results in increased expression of and results in increased secretion of BDNF protein21615740
D015032ZincZinc results in increased expression of BDNF mRNA21615740
D019287Zinc SulfateZinc Sulfate results in increased expression of BDNF mRNA16330358
C049109zolpidem[Triazolam co-treated with zolpidem] results in decreased expression of BDNF protein24367698
C049109zolpidemzolpidem promotes the reaction [CREB1 protein binds to BDNF promoter]24367698
C049109zolpidemzolpidem promotes the reaction [MECP2 protein binds to BDNF promoter]24367698
C049109zolpidemzolpidem results in decreased expression of BDNF mRNA24367698

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0008083growth factor activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway-IBA21873635  
GO:0007202activation of phospholipase C activity-TAS-  
GO:0007267cell-cell signaling-IBA21873635  
GO:0007399nervous system development-TAS2236018  
GO:0007411axon guidance-TAS19036963  
GO:0007416synapse assembly-IDA19036963  
GO:0007422peripheral nervous system development-IBA21873635  
GO:0007613memory-IBA21873635  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0010832negative regulation of myotube differentiation-ISS-  
GO:0021675nerve development-IBA21873635  
GO:0031547brain-derived neurotrophic factor receptor signaling pathway-TAS19036963  
GO:0031550positive regulation of brain-derived neurotrophic factor receptor signaling pathway-TAS19036963  
GO:0038180nerve growth factor signaling pathway-IBA21873635  
GO:0040011locomotion-IBA21873635  
GO:0043524negative regulation of neuron apoptotic process-IBA21873635  
GO:0045664regulation of neuron differentiation-IBA21873635  
GO:0048011neurotrophin TRK receptor signaling pathway-TAS-  
GO:0048668collateral sprouting-IDA19036963  
GO:0048672positive regulation of collateral sprouting-IDA19036963  
GO:0048812neuron projection morphogenesis-IBA21873635  
GO:0050804modulation of chemical synaptic transmission-IBA21873635  
GO:0051965positive regulation of synapse assembly-IDA19036963  
GO:1900122positive regulation of receptor binding-IDA12130635  
GO:1903997positive regulation of non-membrane spanning protein tyrosine kinase activity-TAS-  
GO:2000008regulation of protein localization to cell surface-TAS12130635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IBA21873635  
GO:0005737cytoplasm-ISS-  
GO:0005739mitochondrion-IDA-  
GO:0008021synaptic vesicle-IBA21873635  
GO:0016607nuclear speck-IDA-  
GO:0030424axon-IBA21873635  
GO:0030425dendrite-IBA21873635  
GO:0031410cytoplasmic vesicle-IBA21873635  
GO:0048471perinuclear region of cytoplasm-ISS-  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04722Neurotrophin signaling pathway
hsa05016Huntington's disease
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-166520Signaling by NTRKsTAS
R-HSA-166520Signaling by NTRKsIEA
R-HSA-9006115Signaling by NTRK2 (TRKB)TAS
R-HSA-9006115Signaling by NTRK2 (TRKB)IEA
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesIEA
R-HSA-9024909BDNF activates NTRK2 (TRKB) signalingIEA
R-HSA-9026519Activated NTRK2 signals through RASIEA
R-HSA-9026527Activated NTRK2 signals through PLCG1TAS
R-HSA-9026527Activated NTRK2 signals through PLCG1IEA
R-HSA-9028335Activated NTRK2 signals through PI3KIEA
R-HSA-9028731Activated NTRK2 signals through FRS2 and FRS3TAS
R-HSA-9028731Activated NTRK2 signals through FRS2 and FRS3IEA
R-HSA-9032500Activated NTRK2 signals through FYNTAS
R-HSA-9032500Activated NTRK2 signals through FYNIEA
R-HSA-9032759NTRK2 activates RAC1TAS
R-HSA-9032759NTRK2 activates RAC1IEA
R-HSA-9032845Activated NTRK2 signals through CDK5IEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27344179Associations between smoking behavior-related alleles and the risk of melanoma. (2016 Jul 26)Wu WOncotarget
22205542Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats. (2012 Jun)Chen SLJ Neuroimmune Pharmacol
21463342Alterations of brain-derived neurotrophic factor serum levels in patients with alcohol dependence. (2011 Aug)Zanardini RAlcohol Clin Exp Res
24934904The relationship between serum brain-derived neurotrophic factor (BDNF) and cardiometabolic indices in schizophrenia. (2014 Aug)Nurjono MSchizophr Res
26659122Alcohol dependence-induced regulation of the proliferation and survival of adult brain progenitors is associated with altered BDNF-TrkB signaling. (2016 Dec)Somkuwar SSBrain Struct Funct
19462300Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine. (2009)Haile CNAm J Drug Alcohol Abuse
24067327Increase in brain-derived neurotrophic factor expression in early crack cocaine withdrawal. (2014 Jan)von Diemen LInt J Neuropsychopharmacol
28525828Peripheral immune factors are elevated in women with current or recent alcohol dependence and associated with altered mood and memory. (2017 Jul 1)Wilhelm CJDrug Alcohol Depend
27242447A Lack of Correlation between Brain-Derived Neurotrophic Factor Serum Level and Verbal Memory Performance in Healthy Polish Population. (2016)Wilkosc MFront Neural Circuits
21930150Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. (2011 Dec)Hauser SRPharmacol Biochem Behav
27062604Urinary neurotrophic peptides in postmenopausal women with and without overactive bladder. (2017 Mar)Pennycuff JFNeurourol Urodyn
24377440A positive correlation between serum levels of mature brain-derived neurotrophic factor and negative symptoms in schizophrenia. (2014 Feb 28)Niitsu TPsychiatry Res
21640793Association between Val66Met polymorphism of Brain-Derived Neurotrophic Factor (BDNF) gene and a deficiency of colour vision in alcohol-dependent male patients. (2011 Jul 25)Sery ONeurosci Lett
24676990Oxidative stress and BDNF as possible markers for the severity of crack cocaine use in early withdrawal. (2014 Oct)Sordi AOPsychopharmacology (Berl)
18322102Effector immediate-early gene arc in the amygdala plays a critical role in alcoholism. (2008 Mar 5)Pandey SCJ Neurosci
14973246A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. (2004 Feb 18)Lu LJ Neurosci
26501066Mood Disorders and BDNF Relationship with Alcohol Drinking Trajectories among PLWH Receiving Care. (2014 May)Miguez-Burbano MJJ Alcohol Drug Depend
20674984Brain-derived neurotrophic factor and serotonin transporter gene-linked promoter region genes alter serum levels of brain-derived neurotrophic factor in humans. (2011 Feb)Bhang SJ Affect Disord
29325449Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood. (2018 Jan 12)Marzi SJAm J Psychiatry
22974102The effects of alcohol abstinence on BDNF, ghrelin, and leptin secretions in alcohol-dependent patients with glucose intolerance. (2013 Jan)Kim JHAlcohol Clin Exp Res
20373480Varenicline does not increase serum BDNF levels in patients with nicotine dependence. (2010 Apr)Umene-Nakano WHum Psychopharmacol
23103711Effects of chronic low- and high-dose nicotine on cognitive flexibility in C57BL/6J mice. (2013 Feb 1)Ortega LABehav Brain Res
26022436Brain-Derived Neurotrophic Factor and Delayed Verbal Recall in Crack/Cocaine Dependents. (2015)Viola TWEur Addict Res
20661552Nicotine dependence and serum BDNF levels in male patients with schizophrenia. (2010 Oct)Zhang XYPsychopharmacology (Berl)
17186223Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking. (2007 Mar)Lang UEPsychopharmacology (Berl)
18345022Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. (2008 May)Thomas MJBr J Pharmacol
21949427Neuroticism, depressive symptoms, and serum BDNF. (2011 Oct)Terracciano APsychosom Med
28808012BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors. (2017 Aug 29)Anderson EMProc Natl Acad Sci U S A
21208596Corticotropin-releasing factor, interleukin-6, brain-derived neurotrophic factor, insulin-like growth factor-1, and substance P in the cerebrospinal fluid of civilians with posttraumatic stress disorder before and after treatment with paroxetine. (2011 Aug)Bonne OJ Clin Psychiatry
29357681Corrigendum. (2018 Jan-Dec)-ASN Neuro
26792039Serum Levels of Growth Factors in Alcohol-dependent Patients according to Comorbid Depressive Symptoms. (2016 Feb 29)Han CClin Psychopharmacol Neurosci
19453942Escalating ethanol intake is associated with altered corticostriatal BDNF expression. (2009 Jun)Logrip MLJ Neurochem
26460781Determinants of brain-derived neurotrophic factor (BDNF) in umbilical cord and maternal serum. (2016 Jan)Flock APsychoneuroendocrinology
23488934Blockade of ethanol-induced behavioral sensitization by sodium butyrate: descriptive analysis of gene regulations in the striatum. (2013 Jul)Legastelois RAlcohol Clin Exp Res
23285275BDNF Val66Met variant and smoking in a Chinese population. (2012)Zhang XYPLoS One
27514572Association of testosterone and BDNF serum levels with craving during alcohol withdrawal. (2016 Aug)Heberlein AAlcohol
20390474Mechanisms of illness progression in the recurrent affective disorders. (2010 Nov)Post RMNeurotox Res
20096541Decreased BDNF in patients with antipsychotic naive first episode schizophrenia. (2010 Jun)Jindal RDSchizophr Res
21741029Increased serum brain-derived neurotrophic factor is predictive of cocaine relapse outcomes: a prospective study. (2011 Oct 15)D'Sa CBiol Psychiatry
28303373Viral-mediated overexpression of the Myelin Transcription Factor 1 (MyT1) in the dentate gyrus attenuates anxiety- and ethanol-related behaviors in rats. (2017 Jun)Bahi APsychopharmacology (Berl)
22538247Increase in serum brain-derived neurotrophic factor in met allele carriers of the BDNF Val66Met polymorphism is specific to males. (2012 Jun)Bus BANeuropsychobiology
24109187Role of nucleus accumbens glutamatergic plasticity in drug addiction. (2013)Quintero GCNeuropsychiatr Dis Treat
25747962Prenatal nicotinic exposure augments cardiorespiratory responses to activation of bronchopulmonary C-fibers. (2015 May 1)Zhuang JAm J Physiol Lung Cell Mol Physiol
24990928MeCP2 repression of G9a in regulation of pain and morphine reward. (2014 Jul 2)Zhang ZJ Neurosci
26346883Expression of BDNF and TrkB Phosphorylation in the Rat Frontal Cortex During Morphine Withdrawal are NO Dependent. (2016 Aug)Peregud DICell Mol Neurobiol
20472139Role of neurotrophic factors in behavioral processes: implications for the treatment of psychiatric and neurodegenerative disorders. (2010)Pardon MCVitam Horm
25155311Ethanol and nicotine interaction within the posterior ventral tegmental area in male and female alcohol-preferring rats: evidence of synergy and differential gene activation in the nucleus accumbens shell. (2015 Feb)Truitt WAPsychopharmacology (Berl)
18990365Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. (2009 Apr 15)Graham DLBiol Psychiatry
23653680Targeted brain derived neurotropic factors (BDNF) delivery across the blood-brain barrier for neuro-protection using magnetic nano carriers: an in-vitro study. (2013)Pilakka-Kanthikeel SPLoS One
25408911Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels. (2013)Popa-Wagner AJ Mol Psychiatry
15547445Association study of brain-derived neurotrophic factor gene polymorphism and alcoholism. (2004 Nov)Matsushita SAlcohol Clin Exp Res
21883922Association of BDNF and COMT genotypes with cognitive processing of anti-smoking PSAs. (2011 Nov)Falcone MGenes Brain Behav
29656414Add-On Memantine Treatment for Bipolar II Disorder Comorbid with Alcohol Dependence: A 12-Week Follow-Up Study. (2018 Jun)Lee SYAlcohol Clin Exp Res
24682499The effects of lobeline on nicotine withdrawal-induced depression-like behavior in mice. (2014 Aug)Roni MAPsychopharmacology (Berl)
22173577Recapitulation of the association of the Val66Met polymorphism of BDNF gene with BMI in Koreans. (2012 Sep)Hong KWObesity (Silver Spring)
22193444[Changes of BDNF expression in hippocampus and serum of rats with artificial chronic obstructive pulmonary disease]. (2011 Dec 25)Wang QSheng Li Xue Bao
25660313Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and the risk for alcohol dependence. (2015 Apr 1)Forero DADrug Alcohol Depend
21232579Alterations in BDNF and phospho-CREB levels following chronic oral nicotine treatment and its withdrawal in dopaminergic brain areas of mice. (2011 Mar 17)Kivinummi TNeurosci Lett
25262503TNF-alpha and IL-6 serum levels: neurobiological markers of alcohol consumption in alcohol-dependent patients? (2014 Nov)Heberlein AAlcohol
27453731BDNF Val66Met Polymorphism as a Moderator of Exercise Enhancement of Smoking Cessation Treatment in Anxiety Vulnerable Adults. (2016 Mar)Smits JAMent Health Phys Act
28237884Effects of crack cocaine addiction and stress-related genes on peripheral BDNF levels. (2017 Jul)Rovaris DLJ Psychiatr Res
29174061Pathobiological expression of the brain-derived neurotrophic factor (BDNF) in cerebellar cortex of sudden fetal and infant death victims. (2018 May)Lavezzi AMInt J Dev Neurosci
28889008The interplay between ventro striatal BDNF levels and the effects of valproic acid on the acquisition of ethanol-induced conditioned place preference in mice. (2017 Nov 1)Dos Santos MA JuniorNeurosci Lett
20702043Determinants of serum brain-derived neurotrophic factor. (2011 Feb)Bus BAPsychoneuroendocrinology
15896496A study of the association of (Val66Met) polymorphism in the brain-derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males. (2005 Jun 24)Tsai SJNeurosci Lett
24301752BDNF Val66Met polymorphism and serum concentrations of BDNF with smoking in Thai males. (2013 Oct 24)Suriyaprom KGenet Mol Res
28776866Prenatal androgen receptor activation determines adult alcohol and water drinking in a sex-specific way. (2018 May)Huber SEAddict Biol
29391279Gut microbiota modulates alcohol withdrawal-induced anxiety in mice. (2018 May 1)Xiao HWToxicol Lett
19732758Brain-derived neurotrophic factor and cocaine addiction. (2010 Feb 16)McGinty JFBrain Res
26405456The relationship between brain-derived neurotrophic factor and cognitive functions in alcohol-dependent patients: a preliminary study. (2015)Han CAnn Gen Psychiatry
23023098Brain-derived neurotrophic factor Val66Met polymorphism and alcohol-related phenotypes. (2013 Jan 10)Nedic GProg Neuropsychopharmacol Biol Psychiatry
24993285BDNF SNPs are implicated in comorbid alcohol dependence in schizophrenia but not in alcohol-dependent patients without schizophrenia. (2014 Sep-Oct)Cheah SYAlcohol Alcohol
28430931Joint Effects of the Epigenetic Alteration of Neurotrophins and Cytokine Signaling: A Possible Exploratory Model of Affective Symptoms in Alcohol-Dependent Patients? (2017 May 1)Heberlein AAlcohol Alcohol
15222398Passive smoking elevates neurotrophin levels in tears. (2004 May)Kimata HHum Exp Toxicol
28637174Effect of Prenatal Exposure to Waterpipe Tobacco Smoke on Learning and Memory of Adult Offspring Rats. (2018 Mar 6)Al-Sawalha NNicotine Tob Res
29161446Microglia Activation and Gene Expression Alteration of Neurotrophins in the Hippocampus Following Early-Life Exposure to E-Cigarette Aerosols in a Murine Model. (2018 Mar 1)Zelikoff JTToxicol Sci
25814047Potential role of adolescent alcohol exposure-induced amygdaloid histone modifications in anxiety and alcohol intake during adulthood. (2015 Oct)Pandey SCNeurobiol Dis
27324989Brain-derived neurotrophic factor, impaired glucose metabolism, and bipolar disorder course. (2016 Jun)Mansur RBBipolar Disord
27356518A prospective, longitudinal study of platelet serotonin and plasma brain-derived neurotrophic factor concentrations in major depression: effects of vortioxetine treatment. (2016 Sep)Sagud MPsychopharmacology (Berl)
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