Gene info: ID 6273

Gene Symbol	Pearson Correlation Coefficient
CSTA	0.665
S100A14	0.664
SPINK5	0.618
KRT15	0.613
ADH7	0.602
MUC21	0.597
SERPINB3	0.591
SPRR2F	0.589
TMPRSS11B	0.576
TACSTD2	0.56

Gene Symbol	Pearson Correlation Coefficient
DUSP19	-0.394
RGS7BP	-0.386
NXPH2	-0.386
CCDC177	-0.386
OR14I1	-0.385
MCHR2	-0.385
PHACTR1	-0.378
FAM78B	-0.378
RARB	-0.373
IL1RAPL2	-0.372

DrugBank
CTD

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00768	Olopatadine	Small Molecule	113806-05-6	Approved	Target
DB01373	Calcium	Small Molecule	7440-70-2	Approved\|Nutraceutical	Target
DB01593	Zinc	Small Molecule	7440-66-6	Approved\|Investigational	Target
DB09130	Copper	Small Molecule	7440-50-8	Approved\|Investigational	Target

ID	Drug Name	Action	PubMed
C036990	2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline	"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of S100A2 mRNA"	20816883
D000082	Acetaminophen	Acetaminophen results in decreased expression of S100A2 mRNA	29067470
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of S100A2 protein	20106945
D000447	Aldehydes	Aldehydes results in increased expression of S100A2 mRNA	25014914
C103505	AM 251	AM 251 results in increased expression of S100A2 mRNA	16500647
D000966	Antimony Potassium Tartrate	Antimony Potassium Tartrate results in decreased expression of S100A2 mRNA	28713220
C006632	arsenic trioxide	arsenic trioxide results in increased expression of S100A2 protein	25419056
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of S100A2 mRNA	20106945\|2163298
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in increased expression of S100A2 mRNA	20660070
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of S100A2 mRNA	19619570
D004958	Estradiol	Estradiol results in decreased expression of S100A2 mRNA	23019147
D004958	Estradiol	Estradiol results in increased expression of S100A2 mRNA	19619570
D004958	Estradiol	[Progesterone co-treated with Estradiol] results in increased expression of S100A2 mRNA	17404688
C018475	butyraldehyde	butyraldehyde results in increased expression of S100A2 mRNA	26079696
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of S100A2 mRNA	21457566
D002118	Calcium	Calcium binds to S100A2 protein	17239974
D002118	Calcium	[Zinc binds to S100A2 protein] inhibits the reaction [Calcium binds to S100A2 protein]	17239974
C100187	chloropicrin	chloropicrin affects the expression of S100A2 mRNA	26352163
D003300	Copper	Ascorbic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D003300	Copper	Copper binds to S100A2 protein	21924240
D003300	Copper	Copper promotes the reaction [S100A2 protein binds to S100A2 protein]	21924240
D003300	Copper	Dithiothreitol inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D003300	Copper	Edetic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D003300	Copper	Pentetic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D019327	Copper Sulfate	Copper Sulfate results in increased expression of S100A2 mRNA	19549813
D016572	Cyclosporine	Cyclosporine results in decreased expression of S100A2 mRNA	20106945\|2214713
D016572	Cyclosporine	Cyclosporine results in increased expression of S100A2 mRNA	25562108
C089595	cylindrospermopsin	cylindrospermopsin results in increased expression of S100A2 mRNA	24921660
C014347	decitabine	decitabine affects the expression of S100A2 mRNA	17200013
C014347	decitabine	decitabine affects the expression of S100A2 protein	17200013
C014347	decitabine	decitabine affects the methylation of S100A2 gene	17579622
C014347	decitabine	decitabine results in increased expression of S100A2 mRNA	17785578
C014347	decitabine	decitabine results in increased expression of S100A2 protein	17785578
D003703	Demecolcine	Demecolcine results in increased expression of S100A2 mRNA	23649840
D004041	Dietary Fats	Dietary Fats results in increased expression of S100A2 mRNA	25016146
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of S100A2 mRNA	21527772
D004072	Digitonin	Digitonin promotes the reaction [S100A2 protein binds to S100A2 protein]	21924240
D002117	Calcitriol	Calcitriol results in increased expression of S100A2 mRNA	26485663
D004229	Dithiothreitol	Dithiothreitol inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D004229	Dithiothreitol	Dithiothreitol inhibits the reaction [S100A2 protein binds to S100A2 protein]	21924240
D004492	Edetic Acid	Edetic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D004492	Edetic Acid	Edetic Acid inhibits the reaction [S100A2 protein binds to S100A2 protein]	21924240
C118739	entinostat	entinostat results in increased expression of S100A2 mRNA	27188386
D005472	Fluorouracil	Fluorouracil affects the expression of S100A2 mRNA	16584549
D005472	Fluorouracil	Fluorouracil results in decreased expression of S100A2 protein	15352031
D005472	Fluorouracil	Fluorouracil results in increased expression of S100A2 mRNA	17982676
D005472	Fluorouracil	S100A2 protein affects the susceptibility to Fluorouracil	15352031
D005472	Fluorouracil	TP53 protein affects the reaction [Fluorouracil results in increased expression of S100A2 mRNA]	15016801
D005472	Fluorouracil	TP53 protein promotes the reaction [Fluorouracil results in increased expression of S100A2 mRNA]	17982676
D005557	Formaldehyde	Formaldehyde results in increased expression of S100A2 mRNA	23649840
D006861	Hydrogen Peroxide	Hydrogen Peroxide promotes the reaction [S100A2 protein binds to S100A2 protein]	21924240
C544151	jinfukang	jinfukang results in increased expression of S100A2 mRNA	27392435
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of S100A2 mRNA	24796395
D009532	Nickel	Nickel results in increased expression of S100A2 mRNA	25583101
D009538	Nicotine	Nicotine results in increased expression of S100A2 mRNA	23825647
C568608	PCI 5002	[PCI 5002 co-treated with Zinc] results in increased expression of S100A2 mRNA	18593933
C046012	pentanal	pentanal results in increased expression of S100A2 mRNA	26079696
D004369	Pentetic Acid	Pentetic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]	21924240
D004369	Pentetic Acid	Pentetic Acid inhibits the reaction [S100A2 protein binds to S100A2 protein]	21924240
D011374	Progesterone	Progesterone results in increased expression of S100A2 mRNA	23018184
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in increased expression of S100A2 mRNA	20660070
D011374	Progesterone	[Progesterone co-treated with Estradiol] results in increased expression of S100A2 mRNA	17404688
D011374	Progesterone	Progesterone results in increased expression of S100A2 mRNA	17404688
D011374	Progesterone	Progesterone results in decreased expression of S100A2 mRNA	19635739
D011374	Progesterone	Progesterone results in increased expression of S100A2 mRNA	19690047
C005556	propionaldehyde	propionaldehyde results in increased expression of S100A2 mRNA	26079696
D011794	Quercetin	Quercetin results in increased expression of S100A2 mRNA	21632981
D012834	Silver	Silver results in increased expression of S100A2 mRNA	27131904
C017947	sodium arsenite	sodium arsenite results in decreased expression of S100A2 mRNA	28713220
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of S100A2 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of S100A2 mRNA	19619570
D014635	Valproic Acid	Valproic Acid affects the expression of S100A2 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in increased expression of S100A2 mRNA	23179753\|2800136
D014635	Valproic Acid	Valproic Acid results in increased methylation of S100A2 gene	29154799
D014638	Vanadates	Vanadates results in increased expression of S100A2 mRNA	22714537
D015032	Zinc	[PCI 5002 co-treated with Zinc] results in increased expression of S100A2 mRNA	18593933
D015032	Zinc	Zinc binds to S100A2 protein	17239974
D015032	Zinc	[Zinc binds to S100A2 protein] inhibits the reaction [Calcium binds to S100A2 protein]	17239974
D015032	Zinc	Zinc binds to S100A2 protein	17050004
C088658	zoledronic acid	zoledronic acid results in decreased expression of S100A2 mRNA	24714768

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005509	calcium ion binding	-	NAS	9481475
GO:0005515	protein binding	-	IPI	20188096 20591429 20965181 25416956 26871637
GO:0042802	identical protein binding	-	IPI	16189514 22394450 25416956
GO:0046914	transition metal ion binding	-	IEA	-

PMID	Title (Year)	Author	Journal
15792606	S100A2, a potential marker for early recurrence in early-stage oral cancer. (2005 Apr)	Tsai ST	Oral Oncol
15800916	Overexpression of S100A2 protein as a prognostic marker for patients with stage I non small cell lung cancer. (2005 Aug 20)	Wang H	Int J Cancer
17451265	S100A8 is identified as a biomarker of HPV18-infected oral squamous cell carcinomas by suppression subtraction hybridization, clinical proteomics analysis, and immunohistochemistry staining. (2007 Jun)	Lo WY	J Proteome Res

Gene: S100A2

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Drugs/Compounds

GO/Pathway

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)