Gene: S100A6

6277
2A9|5B10|CABP|CACY|PRA|S10A6
S100 calcium binding protein A6
protein-coding
1q21.3
Ensembl:ENSG00000197956 MIM:114110 Vega:OTTHUMG00000013549 UniprotKB:P06703
NC_000001.11
PubMed
0   ANCO-SNPs
ND
3   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.570e-2 (AD)  4.217e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CD630.896
RPL230.887
RPS20.881
MYL60.876
RPLP00.874
PFN10.872
RPS70.871
RPL140.867
FAU0.867
RPL35A0.866

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.704
OR4F29-0.702
IL1RAPL2-0.158
OR2M4-0.157
ATP12A-0.155
PCDHAC1-0.152
SSX5-0.148
IL17REL-0.147
COL24A1-0.14
CAPN14-0.138

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB11093Calcium CitrateSmall Molecule813-94-5ApprovedTarget
DB11348Calcium PhosphateSmall Molecule10103-46-5ApprovedTarget
ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of S100A6 mRNA"19114083
C0247092,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone"2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone binds to S100A6 protein"16533022
C0261373-hydroxyacetanilide3-hydroxyacetanilide results in decreased expression of S100A6 mRNA18544908
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of S100A6 mRNA"25380136
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C1052604-tert-octylphenol4-tert-octylphenol results in increased expression of S100A6 mRNA17011747
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of S100A6 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of S100A6 mRNA18544908
D016604Aflatoxin B1Aflatoxin B1 affects the expression of S100A6 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of S100A6 mRNA21632981|2164198
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of S100A6 mRNA19770486
D000643Ammonium ChlorideAmmonium Chloride affects the expression of S100A6 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of S100A6 mRNA"22863853
C006632arsenic trioxidearsenic trioxide results in increased expression of S100A6 protein25419056
D001205Ascorbic AcidAscorbic Acid results in increased expression of S100A6 mRNA15372504
D001280AtrazineAtrazine results in increased expression of S100A6 mRNA22378314
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of S100A6 mRNA27858113
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of S100A6 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of and results in increased ubiquitination of S100A6 protein23892563
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of S100A6 mRNA20106945|2163298
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of S100A6 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of S100A6 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of and results in increased ubiquitination of S100A6 protein23892563
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of S100A6 mRNA22228805|2389256
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of S100A6 mRNA21839799
D004958EstradiolEstradiol affects the expression of S100A6 mRNA22574217
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of S100A6 mRNA19619570
D004958EstradiolEstradiol results in decreased expression of S100A6 mRNA23019147
D004958EstradiolEstradiol results in increased expression of S100A6 mRNA19619570
D004958EstradiolEstradiol results in increased expression of S100A6 mRNA19484750
D004958EstradiolEstradiol results in increased expression of S100A6 mRNA17010207
D001622BetaineBetaine inhibits the reaction [Copper deficiency affects the expression of S100A6 protein]25150618
C006780bisphenol Abisphenol A results in decreased expression of S100A6 protein24909818
C006780bisphenol Abisphenol A affects the expression of S100A6 mRNA25181051
C423844BL 11282BL 11282 results in increased expression of S100A6 protein17458497
D001761BleomycinBleomycin affects the expression of S100A6 protein25933445
D002104CadmiumCadmium results in increased expression of S100A6 mRNA21694771
C028031cadmium acetatecadmium acetate results in increased expression of S100A6 mRNA12965115
D019256Cadmium ChlorideCadmium Chloride affects the expression of S100A6 mRNA22110744
D002118CalciumS100A6 protein affects the susceptibility to Calcium15068510
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of S100A6 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of S100A6 mRNA18622026|2733941
D002251Carbon TetrachloridePPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of S100A6 mRNA]18038451|1862202
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of S100A6 mRNA16239168
C010063carbonyl sulfidecarbonyl sulfide results in increased expression of S100A6 mRNA19395590
D002273CarcinogensCarcinogens results in increased expression of S100A6 mRNA16316942
C043211carvedilolcarvedilol results in decreased expression of S100A6 protein20403466
C100187chloropicrinchloropicrin results in increased expression of S100A6 mRNA26352163
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of S100A6 mRNA20938992
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of S100A6 mRNA28472532
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of S100A6 mRNA27858113
C018021cobaltous chloridecobaltous chloride results in decreased expression of S100A6 mRNA19376846
C018021cobaltous chloridecobaltous chloride results in increased expression of S100A6 mRNA24386269
D003300CopperBetaine inhibits the reaction [Copper deficiency affects the expression of S100A6 protein]25150618
D003300CopperCopper deficiency affects the expression of S100A6 protein25150618
D019327Copper SulfateCopper Sulfate results in increased expression of S100A6 mRNA19549813
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in decreased expression of S100A6 mRNA19167446
C009160cyclonitecyclonite results in increased expression of S100A6 mRNA25559034
D016572CyclosporineCyclosporine results in increased expression of S100A6 mRNA25562108
D016572CyclosporineCyclosporine results in increased expression of S100A6 mRNA21865292
C017180decamethrindecamethrin results in increased expression of and results in increased ubiquitination of S100A6 protein23892563
C017180decamethrindecamethrin results in increased expression of S100A6 mRNA23892563
C017180decamethrindecamethrin results in increased expression of and results in increased ubiquitination of S100A6 protein23892563
C017180decamethrindecamethrin results in increased expression of S100A6 mRNA23892563
C014347decitabinedecitabine affects the methylation of S100A6 gene17579622
C014347decitabinedecitabine results in increased expression of S100A6 mRNA19194470
D003976DiazinonDiazinon affects the expression of S100A6 mRNA22546817
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of S100A6 mRNA21266533
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of S100A6 mRNA28962523
D002945CisplatinCisplatin results in increased expression of S100A6 mRNA24280081
D002945CisplatinCisplatin affects the expression of S100A6 mRNA24280081
C000944dicrotophosdicrotophos results in decreased expression of S100A6 mRNA28302478
D004026DieldrinDieldrin affects the expression of S100A6 mRNA22546817
D004041Dietary FatsDietary Fats results in increased expression of S100A6 mRNA22609946
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of S100A6 mRNA21527772
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of S100A6 mRNA28943392
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of S100A6 mRNA19638242
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of S100A6 mRNA25242112
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of S100A6 mRNA17011747
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of S100A6 mRNA17010207|1701174
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of S100A6 mRNA25380136
D004317DoxorubicinDoxorubicin results in increased expression of S100A6 mRNA15033991
C118739entinostatentinostat results in increased expression of S100A6 mRNA26272509|2718838
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
D004785Environmental PollutantsEnvironmental Pollutants affects the expression of S100A6 mRNA19118595
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of S100A6 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of S100A6 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of S100A6 mRNA15834898
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of S100A6 mRNA20938992
D005557FormaldehydeFormaldehyde results in increased expression of S100A6 mRNA18045764
D005557FormaldehydeFormaldehyde results in increased expression of S100A6 protein18045764
D005557FormaldehydeFormaldehyde results in increased expression of S100A6 mRNA18045764
D005632FructoseFructose results in decreased expression of S100A6 mRNA15150374
C039281furanfuran results in increased expression of S100A6 mRNA27387713
D005682GadoliniumS100A6 protein affects the susceptibility to Gadolinium15068510
C419708gefitinib[gefitinib co-treated with naphthalene] affects the expression of S100A6 mRNA20935109
D005839GentamicinsGentamicins results in increased expression of S100A6 mRNA22061828
C004312glycidolglycidol results in increased expression of S100A6 mRNA24915197
C010974glyphosateglyphosate results in increased expression of S100A6 protein24073338
C010974glyphosateglyphosate results in increased expression of S100A6 protein20045496
D006108GraphiteGraphite results in decreased expression of S100A6 protein22157353
D006118GriseofulvinGriseofulvin results in increased expression of S100A6 mRNA12735108
D006493HeparinHeparin affects the expression of S100A6 protein12186470
D006493HeparinHeparin results in increased expression of S100A6 protein17488504
D006830Hydralazine[Hydralazine co-treated with Valproic Acid] results in increased expression of S100A6 mRNA17183730
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of S100A6 mRNA18951874
C016517indole-3-carbinolindole-3-carbinol affects the expression of S100A6 mRNA21396975
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of S100A6 mRNA25613284
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of S100A6 mRNA23086925
C410337K 7174K 7174 results in increased expression of S100A6 mRNA24086573
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of S100A6 mRNA27339419
D008094LithiumLithium results in decreased expression of S100A6 protein18296634
C013099mancozebmancozeb results in increased expression of S100A6 protein21375462
C013099mancozebmancozeb results in increased expression of S100A6 protein21375462
D008345ManganeseManganese results in increased expression of S100A6 mRNA17175027
C025340manganese chloridemanganese chloride results in increased expression of S100A6 mRNA17175027
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of S100A6 mRNA20938992
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of S100A6 mRNA23179753
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of S100A6 mRNA28001369
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of S100A6 protein26558463
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of S100A6 mRNA24810058
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of S100A6 protein26558463
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of S100A6 mRNA16026605
D015735MifepristoneMifepristone results in decreased expression of S100A6 mRNA17584828
C045621miglitolmiglitol results in decreased expression of S100A6 mRNA20667563
C045621miglitolmiglitol results in decreased expression of S100A620667563
C500085muraglitazarmuraglitazar results in decreased expression of S100A6 mRNA21515302
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of S100A6 protein"22001959
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of S100A6 protein"22157353
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of S100A6 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of S100A6 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of S100A6 mRNA"25554681
C031721naphthalene[gefitinib co-treated with naphthalene] affects the expression of S100A6 mRNA20935109
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of S100A6 mRNA25380136
D009532NickelNickel results in increased expression of S100A6 mRNA25583101
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of S100A6 mRNA17616710
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A6 mRNA"19013360
C025256nonylphenolnonylphenol results in increased expression of S100A6 mRNA17010207
C474055octylphenoloctylphenol results in increased expression of S100A6 mRNA17010207
C030110oxaliplatinoxaliplatin results in decreased expression of S100A6 mRNA25729387
D010126OzoneOzone results in increased expression of S100A6 mRNA28652203
D010126OzoneOzone results in increased expression of S100A6 mRNA12763052
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of S100A6 mRNA26272509
D010396PenicillaminePenicillamine results in increased expression of S100A6 mRNA19575532
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of S100A6 protein28126411
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of S100A6 mRNA]19482888
D010634PhenobarbitalPhenobarbital results in increased expression of S100A6 mRNA19482888
D010656PhenylephrineS100A6 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]15652358
D010656PhenylephrineS100A6 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]15652358
D010656PhenylephrineS100A6 protein inhibits the reaction [Phenylephrine results in increased expression of S100B mRNA]15652358
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of S100A6 mRNA26272509
D010695PhlorhizinPhlorhizin results in decreased expression of S100A6 mRNA16123366
C006253pirinixic acidpirinixic acid results in increased expression of S100A6 mRNA23811191
D011192Potassium DichromatePotassium Dichromate results in increased expression of S100A6 protein23718831
D011441PropylthiouracilPropylthiouracil results in decreased expression of S100A6 mRNA24780913
C513428pyrachlostrobinpyrachlostrobin results in increased expression of S100A6 mRNA27029645
D011794QuercetinQuercetin results in increased expression of S100A6 mRNA21632981
C059514resveratrol[Coumestrol co-treated with resveratrol] results in decreased expression of S100A6 mRNA19167446
C059514resveratrol[resveratrol co-treated with Streptozocin] results in increased expression of S100A6 mRNA25905778
C089730rosiglitazonerosiglitazone results in decreased expression of S100A6 mRNA21515302
D012402RotenoneRotenone affects the expression of S100A6 mRNA23186747
C541923sandostatinLARsandostatinLAR results in increased expression of S100A6 mRNA17210224
D012643SeleniumSelenium results in increased expression of S100A6 mRNA19244175
D012822Silicon DioxideSilicon Dioxide results in increased expression of S100A6 mRNA23221170
D019821SimvastatinSimvastatin results in increased expression of S100A6 mRNA17428261
D019821SimvastatinSimvastatin results in increased expression of and results in increased localization of S100A6 protein14973129
D019821SimvastatinSimvastatin results in increased expression of S100A6 mRNA14973129
D019821SimvastatinSimvastatin results in increased expression of S100A6 protein14973129
D012906SmokeSmoke results in increased expression of S100A6 mRNA21095227
C017947sodium arsenitesodium arsenite results in increased expression of S100A6 mRNA21297353
D012969Sodium FluorideSodium Fluoride results in increased expression of S100A6 protein27548804
D053260SootSoot affects the expression of S100A6 mRNA26551751
D053260SootSoot results in increased expression of S100A6 mRNA22461453
D013311Streptozocin[resveratrol co-treated with Streptozocin] results in increased expression of S100A6 mRNA25905778
D014284TriiodothyronineS100A6 protein inhibits the reaction [Triiodothyronine results in increased expression of MYH6 mRNA]15652358
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in decreased expression of S100A6 mRNA15885361
C501413tesaglitazartesaglitazar results in decreased expression of S100A6 mRNA21515302
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of S100A6 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of S100A6 mRNA19619570|2180775
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of S100A6 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of S100A6 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of S100A6 mRNA17035482
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of S100A6 protein24073338
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of S100A6 protein20045496
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of S100A6 mRNA25613284
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of S100A6 mRNA28943392
C009495titanium dioxidetitanium dioxide results in increased expression of S100A6 mRNA23131501|2355797
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of S100A6 mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of S100A6 mRNA28111298
C011559tributyltintributyltin results in increased expression of S100A6 mRNA21683754
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of S100A6 mRNA24935251|2627250
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of S100A6 mRNA19042947
D014502Uranyl NitrateUranyl Nitrate results in increased expression of S100A6 mRNA16316344
D014502Uranyl NitrateUranyl Nitrate results in increased expression of S100A6 protein16316344
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of S100A6 mRNA15885361
D014635Valproic Acid[Hydralazine co-treated with Valproic Acid] results in increased expression of S100A6 mRNA17183730
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of S100A6 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in increased expression of S100A6 mRNA20546886
C034028vanadyl sulfatevanadyl sulfate results in decreased expression of S100A6 mRNA16330358
D014640VancomycinVancomycin results in decreased expression of S100A6 mRNA18930951
C025643vinclozolinvinclozolin affects the expression of S100A6 mRNA19015723
C025643vinclozolinvinclozolin results in decreased expression of S100A6 mRNA23034163
C029297vinylidene chloridevinylidene chloride results in increased expression of S100A6 mRNA26682919
D014810Vitamin EVitamin E results in increased expression of S100A6 mRNA19244175
D024483Vitamin K 3Vitamin K 3 affects the expression of S100A6 mRNA20044591
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A6 mRNA"27188386
D015032ZincZinc binds to S100A6 protein17050004
C088658zoledronic acidzoledronic acid results in decreased expression of S100A6 protein28871336

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005509calcium ion binding-IDA11937060  
GO:0005509calcium ion binding-NAS12577318  
GO:0005515protein binding-IPI10913138  12577318  19724273  20188096  20591429  20965181  
25416956  
GO:0005523tropomyosin binding-IDA19724273  
GO:0008270zinc ion binding-IEA-  
GO:0015075ion transmembrane transporter activity-IEA-  
GO:0042803protein homodimerization activity-IDA10913138  
GO:0042803protein homodimerization activity-IPI11937060  
GO:0044548S100 protein binding-IPI10913138  
GO:0048306calcium-dependent protein binding-IDA10913138  
GO ID GO Term Qualifier Evidence PubMed
GO:0007165signal transduction-TAS16130169  
GO:0007409axonogenesis-NAS12152788  
GO:0034220ion transmembrane transport-IEA-  
GO:0048146positive regulation of fibroblast proliferation-NAS12577318  
GO ID GO Term Qualifier Evidence PubMed
GO:0001726ruffle-IDA10913138  
GO:0005576extracellular region-HDA27068509  
GO:0005634nucleus-IDA10913138  
GO:0005635nuclear envelope-IDA12601007  12805373  
GO:0005635nuclear envelope-NAS12577318  
GO:0005737cytoplasm-IDA10913138  12601007  
GO:0005737cytoplasm-TAS16130169  
GO:0005829cytosol-IDA19724273  
GO:0005886plasma membrane-IDA-  
GO:0031234extrinsic component of cytoplasmic side of plasma membrane-IDA19724273  
GO:0048471perinuclear region of cytoplasm-IDA12118070  
GO:0070062extracellular exosome-HDA19056867  19199708  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20935109EGFR tyrosine kinase inhibition worsens acute lung injury in mice with repairing airway epithelium. (2011 Mar 15)Harada CAm J Respir Crit Care Med
14621194Chromosomal aberrations, profiles of expression of growth-related markers including galectins and environmental hazards in relation to the incidence of chondroid pulmonary hamartomas. (2003)Kayser KPathol Res Pract
27909437Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study. (2016)Svendsen AJFront Immunol