Gene info: ID 6288

Gene: SAA1

GENE ID: 6288

Synonyms: PIG4|SAA|SAA2|TP53I4

Description: serum amyloid A1

Gene type: protein-coding

Location: 11p15.1

dbXrefs: Ensembl:ENSG00000173432 MIM:104750 Vega:OTTHUMG00000166147 UniprotKB:P0DJI8

RefSeq: NG_021330.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 6

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 1.058e-1 (AD) 4.575e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
SAA2	0.876
CYP19A1	0.681
AIM2	0.665
CCL7	0.663
LAMP3	0.66
KRT75	0.654
C15orf48	0.645
IDO1	0.637
CCL8	0.637
CRP	0.635

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ADAMTSL2	-0.315
CHRNB2	-0.31
ATP2C2	-0.31
SLC7A4	-0.307
FOXRED2	-0.302
SEZ6	-0.297
GABRA5	-0.297
NME5	-0.297
FNDC5	-0.296
SLC1A6	-0.291

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00062	Human Serum Albumin	BiotechDrug	9048-46-8	Approved	Target

ID	Drug Name	Action	PubMed
C070046	1,2-dioleoyloxy-3-(trimethylammonium)propane	"[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of SAA1 mRNA"	22129739
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of SAA1 mRNA"	28903501
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran results in increased expression of SAA1 mRNA"	25768209
C557505	3',4'-dimethoxy-alpha-naphthoflavone	"3',4'-dimethoxy-alpha-naphthoflavone inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA1 mRNA]"	21493753
C557505	3',4'-dimethoxy-alpha-naphthoflavone	"3',4'-dimethoxy-alpha-naphthoflavone inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]"	21127131
D000082	Acetaminophen	Acetaminophen results in decreased expression of SAA1 mRNA	26690555\|2906747
D000082	Acetaminophen	Acetaminophen affects the expression of SAA1 mRNA	17562736
D000447	Aldehydes	Aldehydes results in increased expression of SAA1 mRNA	25014914
D000452	Aldrin	Aldrin results in decreased expression of SAA1 mRNA	18579281
C011512	alpha-naphthoflavone	alpha-naphthoflavone analog inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]	21127131
D001151	Arsenic	Arsenic results in increased expression of SAA1 mRNA	19654921
C547126	AZM551248	AZM551248 results in increased expression of SAA1 mRNA	22323515
C000596027	baricitinib	baricitinib inhibits the reaction [OSM protein results in increased expression of SAA1 mRNA]	23968543
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of SAA1 mRNA	26377693
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of SAA1 mRNA	26377693
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the expression of SAA1 mRNA	22342234
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of SAA1 mRNA	23735875\|2590861
D004958	Estradiol	Estradiol affects the expression of SAA1 mRNA	14699072
C006780	bisphenol A	bisphenol A results in decreased expression of SAA1 mRNA	26063408
D000069286	Bortezomib	Bortezomib inhibits the reaction [Lipopolysaccharides results in increased expression of SAA1 mRNA]	15944321
C018475	butyraldehyde	butyraldehyde results in increased expression of SAA1 mRNA	26079696
D019256	Cadmium Chloride	MT3 affects the reaction [Cadmium Chloride affects the expression of SAA1 mRNA]	20371981
D002251	Carbon Tetrachloride	PLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of SAA1 mRNA]	16006527
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in increased expression of SAA1 mRNA	23650126
C100187	chloropicrin	chloropicrin results in increased expression of SAA1 mRNA	26352163
D002784	Cholesterol	"[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of SAA1 mRNA"	22129739
C074702	chromium hexavalent ion	chromium hexavalent ion results in increased expression of SAA1 protein	28596144
D019327	Copper Sulfate	Copper Sulfate results in decreased expression of SAA1 mRNA	18579281
C035996	deacylketoconazole	deacylketoconazole results in decreased expression of SAA1 mRNA	17966066
D003907	Dexamethasone	Dexamethasone results in increased expression of SAA1 mRNA	25047013
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SAA1 mRNA	28628672
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in decreased expression of SAA1 mRNA	28962523
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in increased expression of SAA1 mRNA	27392435
D002945	Cisplatin	Cisplatin results in increased expression of SAA1 mRNA	11099651\|2739243
D004008	Diclofenac	Diclofenac results in increased expression of SAA1 mRNA	26934552
D004041	Dietary Fats	Dietary Fats affects the expression of SAA1 mRNA	17086191\|1845759
D004041	Dietary Fats	Dietary Fats results in increased expression of SAA1 mRNA	22609946
D004041	Dietary Fats	NEIL1 affects the reaction [Dietary Fats results in increased expression of SAA1 mRNA]	21285402
D004041	Dietary Fats	resveratrol inhibits the reaction [Dietary Fats affects the expression of SAA1 mRNA]	17086191
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of SAA1 mRNA	28085963
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of SAA1 mRNA	19850644
D004051	Diethylhexyl Phthalate	PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SAA1 mRNA]	19850644
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of SAA1 mRNA	24535843
D002117	Calcitriol	Calcitriol results in increased expression of SAA1 mRNA	21592394
D002117	Calcitriol	[Testosterone co-treated with Calcitriol] results in increased expression of SAA1 mRNA	21592394
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SAA1 mRNA	17942748
D011345	Fenofibrate	Fenofibrate results in decreased expression of SAA1 mRNA	11798191
D005472	Fluorouracil	Fluorouracil results in increased expression of SAA1 mRNA	16101138
D005557	Formaldehyde	Formaldehyde results in decreased expression of SAA1 mRNA	27664576
C039281	furan	furan results in increased expression of SAA1 mRNA	24183702
D017313	Fenretinide	Fenretinide results in increased expression of SAA1 mRNA	28973697
D007200	Indican	Indican inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]	20000589
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SAA1 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SAA1 mRNA	28628672
D007545	Isoproterenol	Isoproterenol results in increased expression of SAA1 mRNA	21335049
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in increased expression of SAA1 mRNA	27392435
D007654	Ketoconazole	Ketoconazole inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA1 mRNA]	17966066
D007654	Ketoconazole	Ketoconazole results in decreased expression of SAA1 protein	17966066
C008261	lead acetate	lead acetate results in increased expression of SAA1 mRNA	22609695
C045463	leflunomide	leflunomide results in increased expression of SAA1 mRNA	19751817
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SAA1 mRNA	22088672
D008070	Lipopolysaccharides	Bortezomib inhibits the reaction [Lipopolysaccharides results in increased expression of SAA1 mRNA]	15944321
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SAA1 mRNA	15944321\|2147483
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SAA1 protein	15944321\|2147483
D008345	Manganese	Manganese results in increased expression of SAA1 protein	17065364
C025340	manganese chloride	manganese chloride results in increased expression of SAA1 protein	17065364
C013592	mangiferin	mangiferin results in decreased expression of SAA1 mRNA	15135318
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of SAA1 mRNA	21628964
D008628	Mercury	Mercury results in increased expression of SAA1 mRNA	21628964
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of SAA1 mRNA	21628964
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of SAA1 mRNA"	25554681\|2562005
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of SAA1"	21654424
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of SAA1 mRNA"	25554681\|2562005
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of SAA1 mRNA	20974703\|2785383
D015058	1-Naphthylisothiocyanate	pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SAA1 mRNA]	27853831
D015058	1-Naphthylisothiocyanate	PPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SAA1 mRNA]]	27853831
D009532	Nickel	Nickel results in increased expression of SAA1 mRNA	18922574
C029938	nickel sulfate	nickel sulfate results in increased expression of SAA1 mRNA	18651567
C464660	obeticholic acid	obeticholic acid results in increased expression of SAA1 mRNA	27939613
D000069463	Olive Oil	Olive Oil analog affects the expression of SAA1 mRNA	17349074
C510784	ormosil	[ormosil binds to Polyethylene Glycols] which results in decreased expression of SAA1 mRNA	24888373
D010081	Oxazolone	Oxazolone results in increased expression of SAA1 mRNA	15944321
D010081	Oxazolone	Oxazolone results in increased expression of SAA1 protein	15944321
D010126	Ozone	[Ozone co-treated with NOTCH3 gene mutant form] affects the expression of SAA1 mRNA	25658374
D000073878	Palm Oil	Palm Oil affects the expression of SAA1 mRNA	19680557
C016030	pantogab	pantogab results in increased expression of SAA1 mRNA	17379144
C002669	parthenolide	parthenolide results in decreased expression of SAA1 mRNA	16921510
D052638	Particulate Matter	Particulate Matter results in increased expression of SAA1 mRNA	21708214
C046012	pentanal	pentanal results in increased expression of SAA1 mRNA	26079696
D010634	Phenobarbital	Phenobarbital results in increased expression of SAA1 mRNA	19270015
C006253	pirinixic acid	NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of SAA1 mRNA]	17950772
C006253	pirinixic acid	[pirinixic acid co-treated with PPARA] results in decreased expression of SAA1 mRNA	20813756
C006253	pirinixic acid	pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SAA1 mRNA]	27853831
C006253	pirinixic acid	pirinixic acid results in decreased expression of SAA1 mRNA	11798191\|1742611
C006253	pirinixic acid	pirinixic acid results in increased expression of SAA1 mRNA	18445702
C006253	pirinixic acid	PPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SAA1 mRNA]]	27853831
C006253	pirinixic acid	PPARA protein promotes the reaction [pirinixic acid results in decreased expression of SAA1 mRNA]	17950772\|2005976
D010938	Plant Oils	Plant Oils results in increased expression of SAA1 mRNA	23370395
D011092	Polyethylene Glycols	[ormosil binds to Polyethylene Glycols] which results in decreased expression of SAA1 mRNA	24888373
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of SAA1 mRNA	27413110\|2890350
C005556	propionaldehyde	propionaldehyde results in increased expression of SAA1 mRNA	26079696
C432165	pyrazolanthrone	pyrazolanthrone promotes the reaction [IL1A protein results in increased expression of SAA1 mRNA]	12832416
C059514	resveratrol	resveratrol inhibits the reaction [Dietary Fats affects the expression of SAA1 mRNA]	17086191
D012312	Ritodrine	Ritodrine results in increased expression of SAA1 mRNA	23370008
C551534	SGA 360	SGA 360 inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA1 mRNA]	21493753
C551534	SGA 360	SGA 360 inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]	20423157
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of SAA1 mRNA	25895662
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of SAA1 mRNA	23221170
C017947	sodium arsenite	sodium arsenite affects the expression of SAA1 mRNA	29319823
D053260	Soot	Soot results in increased expression of SAA1 mRNA	22461453\|2655175
D013467	Sulindac	Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SAA1 mRNA]	15190207
D015085	2,4,5-Trichlorophenoxyacetic Acid	"2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SAA1 mRNA"	18579281
C013698	tallow	tallow affects the expression of SAA1 mRNA	19680557
D013739	Testosterone	[Testosterone co-treated with Calcitriol] results in increased expression of SAA1 mRNA	21592394
D013739	Testosterone	Testosterone results in increased expression of SAA1 mRNA	21592394
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA1 mRNA]	21493753
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of SAA1 mRNA	28922406
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SAA1 mRNA	17942748
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of SAA1 mRNA	25975270
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of SAA1 mRNA	21889950\|2821309
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of SAA1 mRNA	17949056\|1977048
D013853	Thioacetamide	Thioacetamide results in increased expression of SAA1 mRNA	16297948
C009495	titanium dioxide	titanium dioxide results in increased expression of SAA1 mRNA	21259345\|2355797
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased expression of SAA1 mRNA	28065790
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution affects the expression of SAA1 mRNA	20133372
C479163	tofacitinib	tofacitinib inhibits the reaction [IL6 protein results in increased expression of SAA1 mRNA]	21844139
C479163	tofacitinib	tofacitinib inhibits the reaction [OSM protein results in increased expression of SAA1 mRNA]	23968543
D014118	Toxins, Biological	"Toxins, Biological affects the expression of SAA1 mRNA"	19682533
C034697	transplatin	transplatin results in increased expression of SAA1 mRNA	11099651
D014212	Tretinoin	Tretinoin results in increased expression of SAA1 mRNA	23830798
D014241	Trichloroethylene	Trichloroethylene results in decreased expression of SAA1 mRNA	28973375
D014638	Vanadates	Vanadates results in decreased expression of SAA1 mRNA	22714537
D014752	Vinyl Chloride	Vinyl Chloride results in decreased expression of SAA1 mRNA	18579281
C029297	vinylidene chloride	vinylidene chloride results in increased expression of SAA1 mRNA	26682919
C499198	WAY-169916	WAY-169916 inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]	19903824
C499198	WAY-169916	WAY-169916 inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]	20423157
C088658	zoledronic acid	zoledronic acid results in increased expression of SAA1 mRNA	24714768

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001664	G-protein coupled receptor binding	-	IDA	9892621
GO:0008201	heparin binding	-	IEA	-
GO:0042056	chemoattractant activity	-	IBA	21873635

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000187	activation of MAPK activity	-	IDA	22532826
GO:0006898	receptor-mediated endocytosis	-	TAS	-
GO:0006953	acute-phase response	-	NAS	9815279
GO:0007186	G-protein coupled receptor signaling pathway	-	TAS	-
GO:0007204	positive regulation of cytosolic calcium ion concentration	-	IDA	9892621
GO:0007204	positive regulation of cytosolic calcium ion concentration	-	NAS	7561109
GO:0019221	cytokine-mediated signaling pathway	-	TAS	-
GO:0030168	platelet activation	-	NAS	1697614
GO:0030593	neutrophil chemotaxis	-	NAS	12557751
GO:0044267	cellular protein metabolic process	-	TAS	-
GO:0045087	innate immune response	-	TAS	-
GO:0045785	positive regulation of cell adhesion	-	IDA	9252455 11830469
GO:0045785	positive regulation of cell adhesion	-	NAS	7561109
GO:0048246	macrophage chemotaxis	-	IDA	7561109
GO:0048247	lymphocyte chemotaxis	-	IDA	7636186
GO:0050708	regulation of protein secretion	-	NAS	9605178
GO:0050715	positive regulation of cytokine secretion	-	IDA	12857601
GO:0050716	positive regulation of interleukin-1 secretion	-	NAS	12857601
GO:0050728	negative regulation of inflammatory response	-	NAS	9823935
GO:0050918	positive chemotaxis	-	IEA	-
GO:0060326	cell chemotaxis	-	IBA	21873635

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	NAS	7516407 14718574
GO:0005576	extracellular region	-	TAS	-
GO:0005615	extracellular space	-	IBA	21873635
GO:0005881	cytoplasmic microtubule	-	IDA	22131810
GO:0034364	high-density lipoprotein particle	-	IEA	-
GO:0070062	extracellular exosome	-	HDA	19199708 23533145
GO:0071682	endocytic vesicle lumen	-	TAS	-

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence
R-HSA-1280215	Cytokine Signaling in Immune system	TAS
R-HSA-1606322	ZBP1(DAI) mediated induction of type I IFNs	TAS
R-HSA-162582	Signal Transduction	TAS
R-HSA-166016	Toll Like Receptor 4 (TLR4) Cascade	TAS
R-HSA-166058	MyD88:Mal cascade initiated on plasma membrane	TAS
R-HSA-166166	MyD88-independent TLR4 cascade	TAS
R-HSA-168138	Toll Like Receptor 9 (TLR9) Cascade	TAS
R-HSA-168142	Toll Like Receptor 10 (TLR10) Cascade	TAS
R-HSA-168164	Toll Like Receptor 3 (TLR3) Cascade	TAS
R-HSA-168176	Toll Like Receptor 5 (TLR5) Cascade	TAS
R-HSA-168179	Toll Like Receptor TLR1:TLR2 Cascade	TAS
R-HSA-168181	Toll Like Receptor 7/8 (TLR7/8) Cascade	TAS
R-HSA-168188	Toll Like Receptor TLR6:TLR2 Cascade	TAS
R-HSA-168249	Innate Immune System	TAS
R-HSA-168249	Innate Immune System	IEA
R-HSA-168256	Immune System	TAS
R-HSA-168256	Immune System	IEA
R-HSA-168898	Toll-Like Receptors Cascades	TAS
R-HSA-168928	DDX58/IFIH1-mediated induction of interferon-alpha/beta	TAS
R-HSA-1810476	RIP-mediated NFkB activation via ZBP1	TAS
R-HSA-181438	Toll Like Receptor 2 (TLR2) Cascade	TAS
R-HSA-1834949	Cytosolic sensors of pathogen-associated DNA	TAS
R-HSA-2173782	Binding and Uptake of Ligands by Scavenger Receptors	TAS
R-HSA-3000471	Scavenging by Class B Receptors	TAS
R-HSA-3134963	DEx/H-box helicases activate type I IFN and inflammatory cytokines production	TAS
R-HSA-372790	Signaling by GPCR	TAS
R-HSA-373076	Class A/1 (Rhodopsin-like receptors)	TAS
R-HSA-375276	Peptide ligand-binding receptors	TAS
R-HSA-388396	GPCR downstream signalling	TAS
R-HSA-392499	Metabolism of proteins	TAS
R-HSA-416476	G alpha (q) signalling events	TAS
R-HSA-418594	G alpha (i) signalling events	TAS
R-HSA-444473	Formyl peptide receptors bind formyl peptides and many other ligands	TAS
R-HSA-445989	TAK1 activates NFkB by phosphorylation and activation of IKKs complex	TAS
R-HSA-446652	Interleukin-1 family signaling	TAS
R-HSA-449147	Signaling by Interleukins	TAS
R-HSA-500792	GPCR ligand binding	TAS
R-HSA-5653656	Vesicle-mediated transport	TAS
R-HSA-6785807	Interleukin-4 and 13 signaling	TAS
R-HSA-879415	Advanced glycosylation endproduct receptor signaling	TAS
R-HSA-879415	Advanced glycosylation endproduct receptor signaling	IEA
R-HSA-9020702	Interleukin-1 signaling	TAS
R-HSA-933542	TRAF6 mediated NF-kB activation	TAS
R-HSA-937061	TRIF(TICAM1)-mediated TLR4 signaling	TAS
R-HSA-975138	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	TAS
R-HSA-975155	MyD88 dependent cascade initiated on endosome	TAS
R-HSA-975871	MyD88 cascade initiated on plasma membrane	TAS
R-HSA-977225	Amyloid fiber formation	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
24854450	Association of genetic polymorphisms of SAA1 (rs12218) with myocardial infarction in a Chinese population. (2014 May 9)	Wang BY	Genet Mol Res
22768267	Serum uric acid levels are associated with polymorphism in the SAA1 gene in Chinese subjects. (2012)	Xie X	PLoS One
25656165	Genetic polymorphisms of serum amyloid A1 and coronary artery disease risk. (2015 Mar)	Xie X	Tissue Antigens
23987125	Associations of genetic polymorphisms of SAA1 with cerebral infarction. (2013 Aug 29)	Zhang LJ	Lipids Health Dis
23898911	Rs12218 In SAA1 gene was associated with serum lipid levels. (2013 Jul 30)	Xu XL	Lipids Health Dis
21449704	Polymorphisms in the SAA1 gene are associated with ankle-to-brachial index in Han Chinese healthy subjects. (2011 Aug)	Xie X	Blood Press