| C070379 | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester | "1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [decamethrin results in decreased expression of SCN2A mRNA]" | 25358543 |
| C105351 | 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of SCN2A mRNA" | 23284745 |
| C105351 | 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of SCN2A protein" | 23284745 |
| C029790 | 2,2',3',4,4',5-hexachlorobiphenyl | "[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SCN2A mRNA" | 25510870 |
| C029790 | 2,2',3',4,4',5-hexachlorobiphenyl | "2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of SCN2A mRNA" | 23829299 |
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of SCN2A mRNA" | 21394737 |
| C111118 | 2',3,3',4',5-pentachloro-4-hydroxybiphenyl | "2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of SCN2A mRNA" | 19114083 |
| C489827 | 2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate | "2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate inhibits the reaction [[SCN2A protein co-treated with SCN2B protein co-treated with SCN1B protein] results in increased transport of Sodium]" | 19026681 |
| C081766 | 2,4,4'-trichlorobiphenyl | "[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SCN2A mRNA" | 25510870 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | "[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SCN2A mRNA" | 25510870 |
| C009828 | 2,4,5,2',5'-pentachlorobiphenyl | "[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SCN2A mRNA" | 25510870 |
| C009407 | 2,5,2',5'-tetrachlorobiphenyl | "[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SCN2A mRNA" | 25510870 |
| C009407 | 2,5,2',5'-tetrachlorobiphenyl | "2,5,2',5'-tetrachlorobiphenyl results in decreased expression of SCN2A mRNA" | 23829299 |
| C405354 | 4,5,6,7-tetrabromobenzotriazole | "4,5,6,7-tetrabromobenzotriazole inhibits the reaction [FGF14 protein binds to SCN2A protein]" | 26917740 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCN2A mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCN2A mRNA" | 27188386 |
| C082164 | 4-methoxycinnamate methyl ester | 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of SCN2A mRNA] | 19442820 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCN2A mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCN2A mRNA" | 27188386 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of SCN2A gene | 27153756 |
| C475726 | APETx1, Anthopleura elegantissima | "APETx1, Anthopleura elegantissima analog results in decreased activity of SCN2A protein" | 22972919 |
| C475726 | APETx1, Anthopleura elegantissima | "APETx1, Anthopleura elegantissima promotes the reaction [huwentoxin IV, Selenocosmia huwena results in decreased activity of SCN2A protein]" | 22972919 |
| C475726 | APETx1, Anthopleura elegantissima | "APETx1, Anthopleura elegantissima results in decreased activity of SCN2A protein" | 22972919 |
| C501880 | APETx2 protein, Anthopleura elegantissima | "APETx2 protein, Anthopleura elegantissima promotes the reaction [huwentoxin IV, Selenocosmia huwena results in decreased activity of SCN2A protein]" | 22972919 |
| C501880 | APETx2 protein, Anthopleura elegantissima | "APETx2 protein, Anthopleura elegantissima results in decreased activity of SCN2A protein" | 22972919 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of SCN2A mRNA | 26705709 |
| D001280 | Atrazine | Atrazine results in decreased expression of SCN2A mRNA | 22378314 |
| C044887 | beta-methylcholine | beta-methylcholine affects the expression of SCN2A mRNA | 21179406 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of SCN2A mRNA | 25181051 |
| C006780 | bisphenol A | bisphenol A results in increased methylation of SCN2A gene | 28505145 |
| D002101 | Cacodylic Acid | Cacodylic Acid results in decreased expression of SCN2A mRNA | 16122865 |
| D002392 | Catechin | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of SCN2A mRNA | 24763279 |
| D020916 | Conotoxins | Conotoxins results in decreased activity of SCN2A protein | 26817840 |
| D016572 | Cyclosporine | Cyclosporine results in increased methylation of SCN2A promoter | 27989131 |
| C052570 | cyfluthrin | cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| C017160 | cypermethrin | cypermethrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| C017160 | cypermethrin | cypermethrin binds to SCN2A protein | 9863771 |
| C017160 | cypermethrin | SCN1B protein promotes the reaction [cypermethrin binds to SCN2A protein] | 9863771 |
| C017180 | decamethrin | "1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [decamethrin results in decreased expression of SCN2A mRNA]" | 25358543 |
| C017180 | decamethrin | decamethrin results in decreased expression of SCN2A mRNA | 25358543 |
| C017180 | decamethrin | PD 150606 inhibits the reaction [decamethrin results in decreased expression of SCN2A mRNA] | 25358543 |
| C017180 | decamethrin | Tetrodotoxin inhibits the reaction [decamethrin results in decreased expression of SCN2A mRNA] | 25358543 |
| C017180 | decamethrin | decamethrin results in decreased expression of SCN2A mRNA | 27058123 |
| C017180 | decamethrin | decamethrin affects the reaction [SCN2A protein mutant form results in increased transport of Sodium] | 19442819 |
| C017180 | decamethrin | decamethrin affects the reaction [SCN2A protein results in increased transport of Sodium] | 19442819 |
| D003976 | Diazinon | Diazinon affects the expression of SCN2A mRNA | 22546817 |
| D002945 | Cisplatin | [Cisplatin co-treated with jinfukang] results in increased expression of SCN2A mRNA | 27392435 |
| D004026 | Dieldrin | Dieldrin affects the expression of SCN2A mRNA | 22546817 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in decreased expression of SCN2A mRNA | 19850644 |
| D004051 | Diethylhexyl Phthalate | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SCN2A mRNA] | 19850644 |
| C044267 | fenpropathrin | fenpropathrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| C017690 | fenvalerate | fenvalerate affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| D019833 | Genistein | [Genistein co-treated with Methoxychlor] results in decreased expression of SCN2A mRNA | 21782745 |
| C511402 | Grape Seed Proanthocyanidins | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of SCN2A mRNA | 24763279 |
| C470632 | huwentoxin IV, Selenocosmia huwena | "APETx1, Anthopleura elegantissima promotes the reaction [huwentoxin IV, Selenocosmia huwena results in decreased activity of SCN2A protein]" | 22972919 |
| C470632 | huwentoxin IV, Selenocosmia huwena | "APETx2 protein, Anthopleura elegantissima promotes the reaction [huwentoxin IV, Selenocosmia huwena results in decreased activity of SCN2A protein]" | 22972919 |
| C470632 | huwentoxin IV, Selenocosmia huwena | "huwentoxin IV, Selenocosmia huwena results in decreased activity of SCN2A protein" | 22972919 |
| C544151 | jinfukang | [Cisplatin co-treated with jinfukang] results in increased expression of SCN2A mRNA | 27392435 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of SCN2A mRNA | 24796395 |
| C047781 | lamotrigine | lamotrigine results in decreased activity of SCN2A protein | 11212204 |
| D007854 | Lead | Lead affects the expression of SCN2A mRNA | 28903495 |
| C105338 | makatoxin I | makatoxin I affects the activity of SCN2A protein | 19162162 |
| C042720 | mercuric bromide | mercuric bromide results in increased expression of SCN2A mRNA | 26272509 |
| C042720 | mercuric bromide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCN2A mRNA" | 27188386 |
| D008731 | Methoxychlor | [Genistein co-treated with Methoxychlor] results in decreased expression of SCN2A mRNA | 21782745 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of SCN2A protein | 25809596 |
| C517284 | monomethyl phthalate | monomethyl phthalate affects the expression of SCN2A mRNA | 26924002 |
| C502265 | mu-conotoxin KIIIA, Conus kinoshitai | "mu-conotoxin KIIIA, Conus kinoshitai results in decreased activity of SCN2A protein" | 22972919 |
| C502265 | mu-conotoxin KIIIA, Conus kinoshitai | "mu-conotoxin KIIIA, Conus kinoshitai results in decreased activity of SCN2A protein" | 21962108 |
| C022838 | nickel chloride | nickel chloride affects the expression of SCN2A mRNA | 22546817 |
| C572573 | N-nitroso-tris-chloroethylurea | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN2A mRNA | 27935865 |
| C410127 | PCB 180 | "[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SCN2A mRNA" | 25510870 |
| C100442 | PD 150606 | PD 150606 inhibits the reaction [decamethrin results in decreased expression of SCN2A mRNA] | 25358543 |
| D010654 | Phenylbutyrates | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of SCN2A mRNA" | 23284745 |
| D010654 | Phenylbutyrates | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of SCN2A protein" | 23284745 |
| D010662 | Phenylmercuric Acetate | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCN2A mRNA" | 27188386 |
| D010662 | Phenylmercuric Acetate | Phenylmercuric Acetate results in increased expression of SCN2A mRNA | 26272509 |
| D010672 | Phenytoin | Phenytoin results in decreased activity of SCN2A protein | 11212204 |
| C060836 | pioglitazone | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN2A mRNA | 27935865 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of SCN2A mRNA | 12832660 |
| D011441 | Propylthiouracil | Propylthiouracil results in decreased expression of SCN2A mRNA | 24780913 |
| D012604 | Scorpion Venoms | Scorpion Venoms affects the activity of SCN2A protein | 21887265 |
| D012964 | Sodium | "2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate inhibits the reaction [[SCN2A protein co-treated with SCN2B protein co-treated with SCN1B protein] results in increased transport of Sodium]" | 19026681 |
| D012964 | Sodium | cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| D012964 | Sodium | cypermethrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| D012964 | Sodium | decamethrin affects the reaction [SCN2A protein mutant form results in increased transport of Sodium] | 19442819 |
| D012964 | Sodium | decamethrin affects the reaction [SCN2A protein results in increased transport of Sodium] | 19442819 |
| D012964 | Sodium | fenpropathrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| D012964 | Sodium | fenvalerate affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] | 18538810 |
| D012964 | Sodium | [SCN2A protein binds to SCN1B protein] which affects the transport of Sodium | 9236205 |
| D012964 | Sodium | [SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium | 18538810 |
| D012964 | Sodium | [SCN2A protein co-treated with SCN2B protein co-treated with SCN1B protein] results in increased transport of Sodium | 19026681 |
| D012964 | Sodium | SCN2A protein mutant form results in increased transport of Sodium | 19442819 |
| D012964 | Sodium | SCN2A protein results in increased transport of Sodium | 19442819 |
| C017947 | sodium arsenite | sodium arsenite affects the methylation of SCN2A gene | 28589171 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of SCN2A mRNA | 21354282 |
| D013779 | Tetrodotoxin | Tetrodotoxin inhibits the reaction [decamethrin results in decreased expression of SCN2A mRNA] | 25358543 |
| D013779 | Tetrodotoxin | Tetrodotoxin results in decreased activity of SCN2A protein | 22972919 |
| D013779 | Tetrodotoxin | Tetrodotoxin results in decreased activity of [SCN2A protein binds to SCN1B protein] | 9236205 |
| D019284 | Thapsigargin | 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of SCN2A mRNA] | 19442820 |
| D019284 | Thapsigargin | Thapsigargin results in increased expression of SCN2A mRNA | 19442820 |
| C028800 | toxin II (Anemonia sulcata) | toxin II (Anemonia sulcata) binds to and affects the activity of [SCN2A protein binds to SCN1B protein] | 9236205 |
| D014212 | Tretinoin | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of SCN2A mRNA" | 23284745 |
| D014212 | Tretinoin | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of SCN2A protein" | 23284745 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [ZMYND8 protein binds to SCN2A gene] | 26655721 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [ZMYND8 protein binds to SCN2A promoter] | 26655721 |
| D014212 | Tretinoin | Tretinoin results in increased expression of SCN2A mRNA | 26655721 |
| D014212 | Tretinoin | ZMYND8 protein affects the reaction [Tretinoin results in increased expression of SCN2A mRNA] | 26655721 |
| C013320 | tris(2-butoxyethyl) phosphate | tris(2-butoxyethyl) phosphate affects the expression of SCN2A mRNA | 29024780 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SCN2A mRNA | 19101580|2670570 |