Gene: CCL7

6354
FIC|MARC|MCP-3|MCP3|NC28|SCYA6|SCYA7
C-C motif chemokine ligand 7
protein-coding
17q12
Ensembl:ENSG00000108688 MIM:158106 Vega:OTTHUMG00000132889 UniprotKB:P80098
NC_000017.11
PubMed
0   ANCO-SNPs
ND
3   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.401e-1 (AD)  8.458e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IDO10.973
KRTAP20-10.972
CYP19A10.965
RUFY40.95
ZBP10.944
CCL80.938
IL270.911
LGALS140.897
SIGLEC120.894
KRT750.879

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ATP6V1E2-0.297
SNX22-0.271
NME5-0.254
CDH4-0.25
FOXRED2-0.25
HCN2-0.248
ARSE-0.24
ADAMTSL2-0.238
NLGN3-0.233
SCRT1-0.231

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0700461,2-dioleoyloxy-3-(trimethylammonium)propane"[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of CCL7 mRNA"22129739
C04676015-acetyldeoxynivalenol15-acetyldeoxynivalenol results in increased expression of CCL7 mRNA24793808
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of CCL7 mRNA28329830
C0512461-methylanthraceneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of CCL7 mRNA]28329830
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of CCL7 mRNA19933214
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CCL7 mRNA"23146750
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of CCL7 mRNA"27291303
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CCL7 mRNA"23146750
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCL7 mRNA"23681119
C0432473-acetyldeoxynivalenol3-acetyldeoxynivalenol results in increased expression of CCL7 mRNA24793808
C0261373-hydroxyacetanilide3-hydroxyacetanilide results in decreased expression of CCL7 mRNA18544908
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of CCL7 mRNA19191707
C0297284-phenylenediamine4-phenylenediamine results in increased expression of CCL7 mRNA27585668
C512352abexinostatabexinostat results in decreased expression of CCL7 mRNA19417023
C000615602AB-FUBINACAAB-FUBINACA results in decreased expression of CCL7 mRNA26517302
C496492abrineabrine results in decreased expression of CCL7 mRNA22595364
D000082AcetaminophenAcetaminophen affects the expression of CCL7 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of CCL7 mRNA18544908
D000082AcetaminophenAcetaminophen results in increased expression of CCL7 protein11981759
D000082AcetaminophenCCR2 protein affects the reaction [Acetaminophen results in increased expression of CCL7 protein]11981759
D000082AcetaminophenMAP3K5 protein affects the reaction [Acetaminophen results in increased expression of CCL7 mRNA]18700144
C056165acetovanilloneacetovanillone inhibits the reaction [TNF protein results in increased expression of CCL7 mRNA]22414048
C472668AEOL 10150AEOL 10150 results in decreased expression of CCL7 mRNA12374626
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of CCL7 gene27153756
D000393Air PollutantsAir Pollutants results in increased expression of CCL7 mRNA26618301
D000447AldehydesAldehydes results in increased expression of CCL7 mRNA25014914
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of CCL7 mRNA21298039
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CCL7 mRNA16483693
D000936Antigen-Antibody ComplexAntigen-Antibody Complex results in increased expression of CCL7 mRNA25451590
D000936Antigen-Antibody Complexshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of CCL7 mRNA]25451590
D001149Arsenates[Atrazine co-treated with Arsenates] results in increased expression of CCL7 mRNA18585445
D001151Arsenic[Arsenic results in increased abundance of Arsenicals] which affects the expression of CCL7 mRNA28793237
D001151ArsenicArsenic results in increased expression of CCL7 mRNA18315880
D001152Arsenicals[Arsenic results in increased abundance of Arsenicals] which affects the expression of CCL7 mRNA28793237
C006632arsenic trioxide[arsenic trioxide co-treated with Tretinoin] results in increased expression of CCL7 mRNA19828696
C006632arsenic trioxide[arsenic trioxide co-treated with Tretinoin] results in increased expression of CCL7 protein19828696
C006632arsenic trioxidearsenic trioxide results in increased expression of CCL7 mRNA19828696
C006632arsenic trioxidearsenic trioxide results in increased expression of CCL7 protein19828696
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased expression of CCL7 mRNA"22168577
D016589AstemizoleAstemizole results in decreased expression of CCL7 mRNA20221588
D001280Atrazine[Atrazine co-treated with Arsenates] results in increased expression of CCL7 mRNA18585445
D001280AtrazineAtrazine results in increased expression of CCL7 mRNA22378314
C547126AZM551248AZM551248 results in increased expression of CCL7 mRNA22323515
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of CCL7 mRNA22316170
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CCL7 mRNA22228805|2373587
D004958EstradiolEstradiol affects the expression of CCL7 mRNA15598610
D004958EstradiolEstradiol results in increased expression of CCL7 mRNA19484750
D004958EstradiolEstradiol results in increased expression of CCL7 mRNA17010207
C006780bisphenol Abisphenol A results in increased expression of CCL7 mRNA29275510
C006780bisphenol Abisphenol A results in increased expression of CCL7 mRNA25181051
C006794brevianamide Abrevianamide A results in decreased expression of CCL7 mRNA19818335
C018475butyraldehydebutyraldehyde results in increased expression of CCL7 mRNA26079696
D000001CalcimycinCalcimycin results in increased expression of CCL7 mRNA25451590
D000001Calcimycinshikonin inhibits the reaction [Calcimycin results in increased expression of CCL7 mRNA]25451590
D002118CalciumCCL7 protein results in increased uptake of Calcium10984371
D002118CalciumPiperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium]10843593
D002185CannabidiolCannabidiol results in decreased expression of CCL7 mRNA21542829
D002235CarbofuranCarbofuran results in increased expression of CCL7 mRNA20211217
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CCL7 mRNA17484886
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of CCL7 mRNA21224055
D002635Chenodeoxycholic AcidEGR1 promotes the reaction [Chenodeoxycholic Acid results in increased expression of CCL7 mRNA]21224055
D002784Cholesterol"[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of CCL7 mRNA"22129739
D002791Cholesterol, Dietary"CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]"23462015
D002791Cholesterol, Dietary"[CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased activity of G6PD protein"23462015
D002791Cholesterol, Dietary"[CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased activity of GSR protein"23462015
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL7 mRNA20938992
C023600chromic oxidechromic oxide analog results in increased secretion of CCL7 protein24885771
C000488cladosporincladosporin results in decreased expression of CCL7 mRNA19818335
D003035CobaltTNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA]23503329
D003035Cobalt[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA23503329
D003436Croton OilCroton Oil results in increased expression of CCL7 mRNA19647056
C038459curdlancurdlan affects the expression of CCL7 mRNA19904525
D003520CyclophosphamideCyclophosphamide results in increased expression of CCL7 mRNA15331540|2104116
D016572CyclosporineCyclosporine results in increased expression of CCL7 mRNA23958496
D003840Deoxycholic AcidDeoxycholic Acid results in increased expression of CCL7 mRNA21224055
D003840Deoxycholic AcidEGR1 promotes the reaction [Deoxycholic Acid results in increased expression of CCL7 mRNA]21224055
C007262deoxynivalenoldeoxynivalenol results in increased expression of CCL7 mRNA15371230|1568116
C007262deoxynivalenol"Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL7 mRNA]"15681167
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CCL7 mRNA16054899
D003907DexamethasoneDexamethasone results in decreased expression of CCL7 mRNA22733784
D003907DexamethasoneTNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA]23503329
D003907Dexamethasone[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA23503329
D016264Dextran SulfateDextran Sulfate results in increased expression of CCL7 mRNA19645018
D002945CisplatinCisplatin results in decreased expression of CCL7 mRNA22023808
D004041Dietary Fats"CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]"23462015
D004041Dietary Fats"[CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased activity of G6PD protein"23462015
D004041Dietary Fats"[CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased activity of GSR protein"23462015
D004041Dietary FatsDietary Fats results in increased expression of CCL7 mRNA25016146
D019422Dietary SucroseDietary Sucrose results in increased expression of CCL7 mRNA26033743
C058705diethyl malatediethyl malate affects the expression of CCL7 mRNA24814887
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of CCL7 mRNA21658437
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CCL7 mRNA17010207
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of CCL7 protein17719030
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of CCL7 mRNA19647056
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of CCL7 mRNA21893156
D004317DoxorubicinDoxorubicin results in increased expression of CCL7 mRNA20211217
D004391DustDust results in increased expression of CCL7 mRNA17805423
D004391DustDust results in increased expression of CCL7 protein26882889
D004391DustMYD88 gene mutant form inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D004391Dust[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein26882889
D004391DustPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D004391DustTLR2 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D015118Eicosapentaenoic Acid[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of CCL7 mRNA]22169119
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of CCL7 mRNA15212814
C000499ferric oxideferric oxide results in increased secretion of CCL7 protein24885771
C012976flumequine"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCL7 mRNA"23681119
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of CCL7 mRNA28329830
C007738fluorantheneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of CCL7 mRNA]28329830
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CCL7 protein25051504
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL7 mRNA20938992
C069837fullerene C60fullerene C60 results in increased expression of CCL7 mRNA19167457|2047144
C039281furanfuran results in increased expression of CCL7 mRNA27387713
C002469fusarenon-Xfusarenon-X results in increased expression of CCL7 mRNA24793808
C064925gadodiamidegadodiamide results in increased expression of CCL7 protein20938346
C579046GDC-0152GDC-0152 results in increased expression of CCL7 protein22956632
D005839GentamicinsGentamicins results in decreased expression of CCL7 protein25051504
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]17109745
D005944GlucosamineGlucosamine results in increased expression of CCL7 mRNA17109745
D005944GlucosamineIL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]17109745
D006046Gold[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL7 protein22155353
D006046GoldGold results in increased secretion of CCL7 protein22155353
C412815GW 4064GW 4064 results in increased expression of CCL7 mRNA26655953
D017313FenretinideFenretinide results in increased expression of CCL7 mRNA28973697
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CCL7 mRNA16054899
D0150561-Methyl-3-isobutylxanthineTNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA]23503329
D0150561-Methyl-3-isobutylxanthine[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA23503329
D007545IsoproterenolIsoproterenol results in decreased expression of CCL7 mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of CCL7 mRNA20211217|2428693
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of CCL7 mRNA]25890327
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL7 mRNA"23090859
C433788lipopolysaccharide, E. coli O26-B6"nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL7 mRNA]"23090859
C482199lipopolysaccharide, E coli O55-B5"ATP7A protein mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL7 protein]"23604539
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of CCL7 protein"23604539
C482199lipopolysaccharide, E coli O55-B5"neocuproine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL7 protein]"23604539
C482199lipopolysaccharide, E coli O55-B5"neocuproine promotes the reaction [ATP7A protein mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL7 protein]]"23604539
D008070Lipopolysaccharides[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of CCL7 protein18437699
D008070Lipopolysaccharides(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of CCL7 mRNA]25890327
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CCL7 mRNA22169119|2589032
D008070Lipopolysaccharides[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of CCL7 mRNA]22169119
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CCL7 mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CCL7 mRNA26378955
D008345ManganeseManganese results in increased expression of CCL7 mRNA17175027
C025340manganese chloridemanganese chloride results in increased expression of CCL7 mRNA17175027
C551151manganese ferritemanganese ferrite results in increased secretion of CCL7 protein24885771
D008687MetforminMetformin inhibits the reaction [IL13 protein results in increased expression of CCL7 mRNA]26497364
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL7 mRNA20938992
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CCL7 mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CCL7 mRNA24213012
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of CCL7 mRNA21628967|2320844
C523799MRK 003CCL7 results in increased susceptibility to MRK 00319903844
C500085muraglitazarmuraglitazar results in decreased expression of CCL7 mRNA21515302
D009151Mustard GasMustard Gas results in increased expression of CCL7 mRNA15674843
D009173Mycophenolic AcidMycophenolic Acid results in decreased expression of CCL7 mRNA19818335
D009183MycotoxinsMycotoxins results in decreased expression of CCL7 mRNA19818335
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CCL7 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CCL7 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CCL7 mRNA"19836432|2491129
C031721naphthalenenaphthalene results in increased expression of CCL7 mRNA18978301
C002701neocuproine"neocuproine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL7 protein]"23604539
C002701neocuproine"neocuproine promotes the reaction [ATP7A protein mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL7 protein]]"23604539
C015380neoechinulinneoechinulin results in decreased expression of CCL7 mRNA19818335
C490266neoechinulin Aneoechinulin A results in decreased expression of CCL7 mRNA19818335
D009532NickelNickel results in increased expression of CCL7 mRNA24768652|2558310
D009532NickelTNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA]23503329
D009532Nickel[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA23503329
C022838nickel chloride[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of CCL7 protein18437699
C022838nickel chloride"nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL7 mRNA]"23090859
C022838nickel chloridenickel chloride results in decreased secretion of CCL7 protein18437699
C028007nickel monoxidenickel monoxide results in increased expression of CCL7 mRNA19167457
C029938nickel sulfatenickel sulfate results in increased expression of CCL7 mRNA16166746
D0151124-Nitroquinoline-1-oxide4-Nitroquinoline-1-oxide results in increased expression of CCL7 mRNA22561872
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL7 mRNA27935865
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL7 mRNA27935865
C474055octylphenoloctylphenol results in increased expression of CCL7 mRNA17010207
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL7 mRNA]"15681167
D010047OvalbuminMYD88 gene mutant form inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D010047Ovalbumin[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein26882889
D010047OvalbuminPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D010047OvalbuminTLR2 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of CCL7 mRNA25729387
D010081OxazoloneOxazolone results in increased expression of CCL7 mRNA19647056
D010081OxazoloneOxazolone results in increased expression of CCL7 mRNA21893156
D010126OzoneCCL7 protein results in increased susceptibility to Ozone11777981
D010126Ozone[Ozone co-treated with NOTCH3 gene mutant form] affects the expression of CCL7 mRNA25658374
D010126Ozone[Ozone co-treated with NOTCH4 gene mutant form] affects the expression of CCL7 mRNA25658374
D010126OzoneOzone results in increased expression of CCL7 mRNA11777981
D010126OzoneOzone results in increased expression of CCL7 protein11777981|1892964
D052638Particulate MatterParticulate Matter results in increased expression of CCL7 protein11027454
D052638Particulate MatterOVAL protein promotes the reaction [Particulate Matter results in increased expression of CCL7 protein]23896513
D052638Particulate MatterParticulate Matter results in increased expression of CCL7 protein23896513
D052638Particulate MatterParticulate Matter results in increased expression of CCL7 mRNA26618301
C410127PCB 180PCB 180 affects the expression of CCL7 mRNA21703328
C046012pentanalpentanal results in increased expression of CCL7 mRNA26079696
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL7 mRNA27935865
D010880PiperidinesPiperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium]10843593
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of CCL7 mRNA27989595
D011112Polymyxin BPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D059808PolyphenolsPolyphenols results in decreased expression of CCL7 mRNA16293270
D011192Potassium DichromatePotassium Dichromate results in increased expression of CCL7 mRNA23608068
C479581procyanidin B3[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of CCL7 mRNA]22169119
C005556propionaldehydepropionaldehyde results in increased expression of CCL7 mRNA26079696
D011692Puromycin AminonucleosidePuromycin Aminonucleoside affects the expression of CCL7 mRNA10867541
D011791QuartzQuartz results in increased expression of CCL7 mRNA19836432
C059514resveratrolresveratrol results in increased expression of CCL7 mRNA11588890
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CCL7 mRNA16054899
C089730rosiglitazonerosiglitazone results in decreased expression of CCL7 mRNA21515302
C093642SB 203580SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of CCL7 mRNA]28329830
C016101shikoninshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of CCL7 mRNA]25451590
C016101shikoninshikonin inhibits the reaction [Calcimycin results in increased expression of CCL7 mRNA]25451590
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CCL7 mRNA25895662
D012822Silicon Dioxide[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL7 protein22155353
D012822Silicon DioxideSilicon Dioxide results in increased expression of CCL7 mRNA23221170
D012822Silicon DioxideSilicon Dioxide results in increased expression of CCL7 mRNA22431001
D012834SilverSilver results in decreased expression of CCL7 mRNA27131904
D012906SmokeSmoke affects the expression of CCL7 mRNA23693141
C017947sodium arsenitesodium arsenite results in increased expression of CCL7 mRNA28595984
C017947sodium arsenitesodium arsenite results in increased expression of CCL7 mRNA21911445
D053260SootSoot results in decreased expression of CCL7 mRNA22461453
D053260SootSoot results in increased expression of CCL7 mRNA22461453|2655175
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CCL7 mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CCL7 mRNA26378955
D016559TacrolimusTacrolimus results in increased expression of CCL7 mRNA23958496
D013629TamoxifenTamoxifen results in decreased expression of CCL7 mRNA25123088
D013656Taurocholic AcidEGR1 promotes the reaction [Taurocholic Acid results in increased expression of CCL7 mRNA]21224055
D013656Taurocholic AcidTaurocholic Acid results in increased expression of CCL7 mRNA21224055
D013739TestosteroneTestosterone results in decreased expression of CCL7 mRNA19693291
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCL7 mRNA21296121
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CCL7 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [EGF protein results in increased expression of CCL7 mRNA]15667827
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCL7 mRNA19933214
D013853ThioacetamideThioacetamide results in increased expression of CCL7 protein25051504
D013864Thioglycolates[CCL2 gene affects the susceptibility to Thioglycolates] which affects the secretion of CCL7 protein19641140
C009495titanium dioxidetitanium dioxide results in increased expression of CCL7 mRNA19464567|2125934
C402696TMC 120ATMC 120A results in decreased expression of CCL7 mRNA19818335
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of CCL7 mRNA24096154
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of CCL7 protein24096154
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CCL7 mRNA20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution deficiency inhibits the reaction [[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of CCL7 protein]24096154
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of and results in increased secretion of CCL7 protein26609137
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of and results in increased secretion of CCL7 protein27818348
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CCL7 protein27793746
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of CCL7 mRNA"19647056
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of CCL7 mRNA25729387
D019772TopotecanTopotecan results in increased expression of CCL7 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of CCL7 mRNA"19682533
D014212Tretinoin[arsenic trioxide co-treated with Tretinoin] results in increased expression of CCL7 mRNA19828696
D014212Tretinoin[arsenic trioxide co-treated with Tretinoin] results in increased expression of CCL7 protein19828696
D014212TretinoinTretinoin results in increased expression of CCL7 mRNA19828696
D014212TretinoinTretinoin results in increased expression of CCL7 protein19828696
C011559tributyltintributyltin results in decreased expression of CCL7 mRNA21683754
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of CCL7 mRNA21893156
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of CCL7 mRNA17982090
C057693troglitazonetroglitazone results in decreased expression of CCL7 mRNA21515302
C057693troglitazonetroglitazone inhibits the reaction [TNF protein results in increased expression of CCL7 mRNA]12732648
D014635Valproic AcidValproic Acid results in decreased methylation of CCL7 gene29154799
D001335Vehicle EmissionsVehicle Emissions results in increased expression of CCL7 protein11027454
D001335Vehicle EmissionsVehicle Emissions affects the methylation of CCL7 gene25560391
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL7 mRNA27935865
D015032ZincTNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA]23503329
D015032Zinc[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA23503329
D015054ZymosanZymosan results in increased secretion of CCL7 protein19641140

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  26095031  
GO:0008009chemokine activity-IBA21873635  
GO:0008009chemokine activity-IDA10072545  
GO:0008201heparin binding-IEA-  
GO:0031726CCR1 chemokine receptor binding-IPI7545673  10660125  
GO:0031727CCR2 chemokine receptor binding-IEA-  
GO:0048020CCR chemokine receptor binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0002548monocyte chemotaxis-IBA21873635  
GO:0002548monocyte chemotaxis-IC10660125  
GO:0006874cellular calcium ion homeostasis-TAS10770925  
GO:0006935chemotaxis-TAS9780207  
GO:0006954inflammatory response-IBA21873635  
GO:0007010cytoskeleton organization-IDA10072545  
GO:0007165signal transduction-TAS10201901  10770925  
GO:0007186G-protein coupled receptor signaling pathway-IBA21873635  
GO:0007267cell-cell signaling-TAS7916328  
GO:0008360regulation of cell shape-IDA10072545  
GO:0010332response to gamma radiation-IEA-  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0030335positive regulation of cell migration-IDA7545673  
GO:0030593neutrophil chemotaxis-IBA21873635  
GO:0043547positive regulation of GTPase activity-IBA21873635  
GO:0048245eosinophil chemotaxis-IBA21873635  
GO:0048245eosinophil chemotaxis-IDA10072545  
GO:0048247lymphocyte chemotaxis-IBA21873635  
GO:0070098chemokine-mediated signaling pathway-IBA21873635  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IBA21873635  
GO:0071346cellular response to interferon-gamma-IBA21873635  
GO:0071347cellular response to interleukin-1-IBA21873635  
GO:0071356cellular response to tumor necrosis factor-IBA21873635  
GO:0071361cellular response to ethanol-IEA-  
GO:2000503positive regulation of natural killer cell chemotaxis-IDA7545673  
GO ID GO Term Qualifier Evidence PubMed
GO:0005615extracellular space-IBA21873635  
GO:0005623cell-IEA-  
KEGG ID KEGG Term
hsa04060Cytokine-cytokine receptor interaction
hsa04062Chemokine signaling pathway
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29616282A large lung gene expression study identifying IL1B as a novel player in airway inflammation in COPD airway epithelial cells. (2018 Jun)Yi GInflamm Res
25970596Altered activation of innate immunity associates with white matter volume and diffusion in first-episode psychosis. (2015)Mantyla TPLoS One
26424214Plasma Chemokine signature correlates with lung goblet cell hyperplasia in smokers with and without chronic obstructive pulmonary disease. (2015 Sep 30)Kim VBMC Pulm Med