Gene: BID

637
FP497
BH3 interacting domain death agonist
protein-coding
22q11.21
Ensembl:ENSG00000015475 MIM:601997 Vega:OTTHUMG00000150087 UniprotKB:P55957
NC_000022.11
PubMed
CD|OD|ND|AD
49   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.953e-1 (AD)  9.619e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KAT80.907
SSU720.904
UBE2L30.899
ARL2BP0.891
THYN10.889
VPS720.888
MAP1LC3B0.887
WDR450.884
DGUOK0.883
NDUFV20.881

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.771
OR4F29-0.736
KLRB1-0.348
IL2RB-0.297
IFNG-0.287
CETP-0.279
KLRF1-0.276
TBX21-0.275
GZMK-0.271
FCRL3-0.259

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C55429110-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one"10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one affects the localization of BID protein"20833157
C55429110-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one"10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one affects the localization of BID protein alternative form"20833157
C55429110-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one"CASP8 protein affects the susceptibility to [10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one affects the localization of BID protein alternative form]"20833157
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased expression of BID protein"24515801
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Diclofenac results in increased activity of BID protein]"18191430
C5524201-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane"1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased expression of BID protein modified form"20674558
C0374131,3-dinitropyrene"1,3-dinitropyrene results in decreased expression of BID protein"17240030
C0333101,8-dinitropyrene"1,8-dinitropyrene results in increased expression of BID protein"17240030
C0326681-nitropyrene1-nitropyrene results in increased expression of BID protein17240030
C0673721-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline"1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline results in increased expression of BID mRNA"15447660
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased expression of BID mRNA"20453058
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of BID mRNA"27589474
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane results in increased cleavage of BID protein"12788809
C5622542'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione"2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione affects the localization of BID protein"21741372
C5622542'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione"2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased cleavage of and affects the localization of BID protein"21741372
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of BID mRNA"21346803
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased degradation of BID protein]27032576
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneBCL2 protein inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]]20856197
C450643(2)-5,6,7,8,4'-pentamethoxyflavanone"(2)-5,6,7,8,4'-pentamethoxyflavanone results in decreased expression of BID protein"19450678
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in increased expression of BID mRNA"20406850
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of BID mRNA"21346803
C00059917928-O-acetylbetulin-3-ylglucopyranoside28-O-acetylbetulin-3-ylglucopyranoside results in decreased expression of BID protein22343715
C00059917928-O-acetylbetulin-3-ylglucopyranosideCA 074 methyl ester inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased expression of BID protein]22343715
C0059262-amino-4-hydroxy-6-formylpteridine2-amino-4-hydroxy-6-formylpteridine results in decreased expression of BID protein16019850
C5003442-methoxyestradiol-3,17-bis-O,O-sulfamate"2-methoxyestradiol-3,17-bis-O,O-sulfamate results in increased cleavage of BID protein"15258464
C5047113,4-dideoxyglucosone-3-ene"3,4-dideoxyglucosone-3-ene results in increased cleavage of BID protein"16046310
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased cleavage of and results in decreased expression of BID protein19481069
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole[Camptothecin co-treated with 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] results in increased cleavage of and results in decreased expression of BID protein19481069
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of BID mRNA"18648102
C525246(4,4-dimethyl-2,2-bipyridine)(acetylacetonate)copper(II)"(4,4-dimethyl-2,2-bipyridine)(acetylacetonate)copper(II) results in increased expression of BID protein"22540380
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BID mRNA"27188386
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of BID mRNA19191707
C5843684'-methoxy licoflavanone4'-methoxy licoflavanone results in decreased expression of BID protein23850732
C0789564-methylthioamphetamine4-methylthioamphetamine results in increased expression of BID mRNA23820845
C0789564-methylthioamphetamine4-methylthioamphetamine results in increased expression of BID protein modified form23820845
C0789564-methylthioamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA"23820845
C0789564-methylthioamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form"23820845
C0415944-nonylphenol4-nonylphenol results in increased cleavage of and results in increased activity of BID protein22056370
C1109625,6-dichlorobenzimidazole"5,6-dichlorobenzimidazole promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]"15688023
C5582885-methylselenylmethyl-2'-deoxyuridine5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of BID protein22002103
C5582895-phenylselenylmethyl-2'-deoxyuridine5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of BID protein22002103
C5715326-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased expression of BID protein25316768
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BID mRNA"27188386
C5319376-O-angeloylenolin6-O-angeloylenolin results in increased cleavage of BID protein21192922
C5805996-OH-BDE-476-OH-BDE-47 results in decreased expression of BID mRNA27589474
C0548527-hydroxystaurosporine[7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of BID protein15767555
C0030017-ketocholesterol7-ketocholesterol results in decreased expression of BID protein25845326
C0030017-ketocholesterolAcetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]25845326
C0030017-ketocholesterolBAY 11-7085 inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]25845326
C0030017-ketocholesterolquercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]25845326
C501332ABT-737[ABT-737 co-treated with Celecoxib] results in increased cleavage of BID protein20104024
D000082AcetaminophenAcetaminophen results in decreased expression of BID mRNA21420995|2570463
D000082Acetaminophen[Acetaminophen co-treated with dioscin] results in increased expression of BID protein22939915
D000082AcetaminophenAcetaminophen results in increased expression of BID protein20355050
D000082AcetaminophenPlant Extracts inhibits the reaction [Acetaminophen results in increased expression of BID protein]20355050
C043377acetochloracetochlor results in increased expression of BID protein25291404
C487680acetylbritannilatoneacetylbritannilatone analog results in increased phosphorylation of BID protein27262408
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]16169029
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]17574045
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cordycepin results in decreased expression of BID protein]21310227
D000111AcetylcysteineAcetylcysteine inhibits the reaction [gingerol results in decreased expression of BID protein]25034532
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein]23711929
D000111Acetylcysteine[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [sanguinarine results in increased cleavage of BID protein]23660334
D000111AcetylcysteineAcetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]25845326
D000171AcroleinAcrolein affects the localization of BID protein17320762
D000171AcroleinAcrolein results in increased cleavage of BID protein17320762
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of BID mRNA19770486
C004363alantolactonealantolactone results in increased cleavage of BID protein22721982
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of BID mRNA28070108
C000154alpinumisoflavonealpinumisoflavone results in decreased expression of BID protein23850732
C077990alvocidib[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of BID protein15634644
C077990alvocidib[alvocidib co-treated with TNFSF10 protein] results in decreased expression of BID protein16951203
C077990alvocidibalvocidib results in increased cleavage of BID protein11464216|1217077
C077990alvocidibBCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of BID protein]12170773
C077990alvocidibBoc-D-FMK inhibits the reaction [alvocidib results in increased cleavage of BID protein]11464216
C077990alvocidib[Imatinib Mesylate co-treated with alvocidib] results in increased activity of BID protein12231544
D000638Amiodarone[TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein21292685
D000643Ammonium ChlorideAmmonium Chloride affects the expression of BID mRNA16483693
D003913DextroamphetamineDextroamphetamine results in increased expression of BID mRNA23820845
D003913DextroamphetamineDextroamphetamine results in increased expression of BID protein modified form23820845
D003913Dextroamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA"23820845
D003913Dextroamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form"23820845
C030419andrographolide[andrographolide co-treated with Cisplatin] results in increased expression of BID mRNA24563380
C030419andrographolideandrographolide results in increased expression of BID mRNA24563380
C030419andrographolideandrographolide results in increased expression of BID protein24563380
C030419andrographolideandrographolide inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]20946909
C030419andrographolideandrographolide promotes the reaction [Penicillamine inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]]20946909
C030419andrographolidePenicillamine promotes the reaction [andrographolide inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]]20946909
D000841AnisomycinAnisomycin results in increased cleavage of and results in increased activity of BID protein18241849
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of BID mRNA24449571
D047310ApigeninApigenin results in increased expression of BID protein24144774
D016718Arachidonic AcidArachidonic Acid results in increased cleavage of BID protein19720122
D016718Arachidonic AcidFADD protein promotes the reaction [Arachidonic Acid results in increased cleavage of BID protein]19720122
C061640arjunolic acidarjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of BID protein]21420465
D001151ArsenicArsenic results in increased expression of BID mRNA19945496
C058317arsenic disulfidearsenic disulfide results in decreased expression of BID protein24192507
C006632arsenic trioxidearsenic trioxide affects the cleavage of BID protein15131059
C006632arsenic trioxide[arsenic trioxide co-treated with Curcumin] results in decreased expression of BID protein27430728
C006632arsenic trioxide[arsenic trioxide co-treated with Curcumin] results in increased expression of BID protein27430728
C006632arsenic trioxide[arsenic trioxide co-treated with esculetin] results in increased cleavage of BID protein19428345
C006632arsenic trioxide[arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of BID protein21889928
C006632arsenic trioxide[arsenic trioxide co-treated with Quercetin] results in increased cleavage of BID protein18359480
C006632arsenic trioxide[arsenic trioxide co-treated with TNF protein] results in increased cleavage of and results in increased activity of BID protein17673311
C006632arsenic trioxidearsenic trioxide results in decreased expression of BID protein21418039|2557460
C006632arsenic trioxidearsenic trioxide results in increased activity of BID protein20605902
C006632arsenic trioxidearsenic trioxide results in increased cleavage of and results in increased activity of BID protein12851490|1566511
C006632arsenic trioxidearsenic trioxide results in increased cleavage of BID protein10648417|1936412
C006632arsenic trioxideCurcumin promotes the reaction [arsenic trioxide results in increased activity of BID protein]20605902
C006632arsenic trioxideDeoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]23041229
C006632arsenic trioxideGenistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]18546268
C006632arsenic trioxidepyrazolanthrone promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]16972261
C006632arsenic trioxideTP53 protein inhibits the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]12851490
C006632arsenic trioxideU 0126 promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]16972261
C006632arsenic trioxide"arsenic trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of BID protein]"28587418
C006632arsenic trioxidearsenic trioxide affects the expression of BID protein18618274
C006632arsenic trioxidearsenic trioxide results in increased cleavage of BID protein14726646
D001241Aspirin[Aspirin co-treated with TNFSF10 protein] results in increased cleavage of BID protein18483385
D001241AspirinAspirin results in increased cleavage of BID protein15976387
D001241AspirinCASP8 affects the reaction [Aspirin results in increased cleavage of BID protein]15976387
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased expression of and results in increased cleavage of BID protein18339080
D000069059Atorvastatin CalciumMevalonic Acid inhibits the reaction [Atorvastatin Calcium results in decreased expression of and results in increased cleavage of BID protein]18339080
D000069059Atorvastatin CalciumU 0126 inhibits the reaction [Atorvastatin Calcium results in decreased expression of and results in increased cleavage of BID protein]18339080
D001280AtrazineAtrazine results in decreased expression of BID mRNA22378314
C010329azadirachtinazadirachtin results in increased expression of BID mRNA20429769
C040929bafilomycin A1bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]28378122
C040929bafilomycin A1bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]28378122
C040929bafilomycin A1bafilomycin A1 results in increased expression of BID protein modified form28378122
C416282BAY 11-7085BAY 11-7085 inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]25845326
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BID protein"15698582
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in decreased expression of BID protein15698582
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BID protein15698582
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BID protein16041517
D001564Benzo(a)pyreneNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of BID protein]16041517
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BID mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BID mRNA22228805
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [GW 7845 results in increased cleavage of BID protein]17400580
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Topotecan results in increased cleavage of BID protein]19812371
C427308benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [silybin results in increased cleavage of BID protein]16777994
C427308benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [GW 7845 results in increased cleavage of BID protein]17400580
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Cadmium results in increased cleavage of BID protein]10970901
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of BID protein]19360361
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone"benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [N,N-dimethylphytosphingosine results in increased cleavage of BID protein]"19481559
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [rubimaillin results in increased cleavage of BID protein]19716835
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Cadmium results in increased cleavage of BID protein]10970901
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Lithocholic Acid results in increased cleavage of and results in increased activity of BID protein]19054763
C027870berbamineberbamine results in decreased expression of BID protein19960011
D004958EstradiolEstradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA]19426747
D004958EstradiolEstradiol results in decreased expression of BID mRNA19426747
D004958EstradiolEstradiol results in increased expression of BID mRNA20106945
C099952bifenthrinbifenthrin results in increased expression of BID mRNA26071804
C006780bisphenol Abisphenol A results in decreased methylation of BID gene22576693
C006780bisphenol Abisphenol A results in increased expression of BID mRNA22576693
C006780bisphenol Abisphenol A affects the expression of BID mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of BID mRNA26982218
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of BID mRNA22434021
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of BID mRNA17553608
C476029Boc-D-FMKBoc-D-FMK inhibits the reaction [alvocidib results in increased cleavage of BID protein]11464216
D000069286Bortezomib[Bortezomib co-treated with Butyrates] results in decreased expression of BID protein12893773
D000069286Bortezomib[Bortezomib co-treated with TNFSF10 protein] results in increased cleavage of BID protein19261616
D000069286Bortezomib[Bortezomib co-treated with vorinostat] results in decreased expression of BID protein12893773
D000069286BortezomibBortezomib promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]12902978
D000069286BortezomibBortezomib results in increased cleavage of BID protein17898295
D000069286Bortezomib[Bortezomib results in increased susceptibility to and results in increased activity of TNFSF10 protein] which results in increased cleavage of BID protein17326159
D000069286Bortezomib[TNFSF10 protein co-treated with Bortezomib] results in increased cleavage of BID protein15930312
D000069286Bortezomib[vorinostat co-treated with Bortezomib] results in increased cleavage of BID protein17351739
C023623brassinolidebrassinolide results in decreased expression of BID protein20833159
D002087Butyrates[Bortezomib co-treated with Butyrates] results in decreased expression of BID protein12893773
C400541CA 074 methyl esterCA 074 methyl ester inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased expression of BID protein]22343715
C400541CA 074 methyl esterCA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein]28378122
C400541CA 074 methyl esterCA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]28378122
D002104Cadmiumbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Cadmium results in increased cleavage of BID protein]10970901
D002104Cadmiumbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Cadmium results in increased cleavage of BID protein]10970901
D002104CadmiumCadmium results in increased cleavage of BID protein10970901
D002104CadmiumCadmium inhibits the reaction [TNF protein results in increased cleavage of BID protein]16263807
C028031cadmium acetateAcetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]16169029
C028031cadmium acetatecadmium acetate results in increased cleavage of and results in increased localization of BID protein16169029
C028031cadmium acetatecadmium acetate results in increased cleavage of BID protein15450950|1616902
C028031cadmium acetateCASP8 affects the reaction [cadmium acetate results in increased cleavage of BID protein]15450950|1616902
C028031cadmium acetateisoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]15450950|1616902
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of BID mRNA21457566
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BID21787858
D019256Cadmium Chloridearjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of BID protein]21420465
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of BID protein19887573
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BID protein21420465
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [TNF protein results in increased cleavage of BID protein]16263807
C034939cadmium sulfidecadmium sulfide results in decreased expression of BID mRNA27866839
D002110CaffeineCaffeine inhibits the reaction [silybin results in increased cleavage of BID protein]16777994
D002166Camptothecin[Camptothecin co-treated with 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] results in increased cleavage of and results in decreased expression of BID protein19481069
D002166Camptothecin[Camptothecin co-treated with FAS protein] results in increased cleavage of BID protein19633536
D002166CamptothecinCamptothecin results in increased cleavage of and results in decreased expression of BID protein19481069
D002211CapsaicinCapsaicin promotes the reaction [TNFSF10 results in increased cleavage of BID protein]22200406
D002211CapsaicinCapsaicin results in increased cleavage of BID protein19502594
D002211CapsaicinCapsaicin results in increased expression of BID mRNA19502594
D002220CarbamazepineCarbamazepine affects the expression of BID mRNA24752500|2597931
C111238carboxycinnamic acid bishydroxamidecarboxycinnamic acid bishydroxamide results in increased cleavage of BID protein15897598
C054133casticincasticin results in increased expression of BID protein27862857
D002392CatechinCatechin results in increased cleavage of and results in increased activity of BID protein20206613
D000068579Celecoxib[ABT-737 co-treated with Celecoxib] results in increased cleavage of BID protein20104024
D000068579CelecoxibCelecoxib results in increased cleavage of BID protein15197583
D000068579CelecoxibTNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of BID protein]15572759
C469298CEP-11004CEP-11004 inhibits the reaction [sodium arsenite results in increased expression of BID mRNA]16166651
C039671ciglitazoneDDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of BID protein]21067863
C039671ciglitazone[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of BID protein21067863
C045645cilostazolcilostazol inhibits the reaction [Nitroprusside results in decreased expression of BID protein modified form]18311796
C045645cilostazolcilostazol inhibits the reaction [Nitroprusside results in increased cleavage of and results in increased localization of BID protein]18311796
C012843cinnamic aldehydecinnamic aldehyde results in increased cleavage of BID protein15964311
C063451cinobufotalincinobufotalin results in increased activity of BID protein22898211
C057741clavulone IIclavulone II results in increased cleavage of BID protein15920677
C018021cobaltous chloridecobaltous chloride results in decreased expression of BID mRNA19320972
D003042CocaineCocaine affects the expression of BID mRNA15681117
C463759codonoposidecodonoposide results in increased cleavage of and affects the localization of BID protein15863893
D003300Copper"[Copper co-treated with di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone] results in increased cleavage of BID protein"21750178
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of BID mRNA20971185
D003300CopperCopper analog results in increased cleavage of BID protein22000994
C464760copper-1,10-phenanthroline"copper-1,10-phenanthroline results in decreased expression of BID protein"24638265
D019327Copper Sulfateandrographolide inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]20946909
D019327Copper Sulfateandrographolide promotes the reaction [Penicillamine inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]]20946909
D019327Copper SulfateCopper Sulfate results in decreased expression of and results in increased cleavage of BID protein20946909
D019327Copper SulfatePenicillamine inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]20946909
D019327Copper SulfatePenicillamine promotes the reaction [andrographolide inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]]20946909
C058120cordycepinAcetylcysteine inhibits the reaction [cordycepin results in decreased expression of BID protein]21310227
C058120cordycepincordycepin results in decreased expression of BID protein21310227
C029892cupric chloridecupric chloride results in increased expression of BID mRNA17211630
D003474Curcumin[arsenic trioxide co-treated with Curcumin] results in decreased expression of BID protein27430728
D003474Curcumin[arsenic trioxide co-treated with Curcumin] results in increased expression of BID protein27430728
D003474CurcuminCurcumin promotes the reaction [arsenic trioxide results in increased activity of BID protein]20605902
D003513Cycloheximide[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein12925536
D003513CycloheximideCycloheximide inhibits the reaction [vorinostat results in increased cleavage of BID protein]11535817
D003513CycloheximideITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein]12925536
D003513CycloheximideITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein]12925536
D016572CyclosporineCyclosporine results in increased expression of BID mRNA20106945
C089595cylindrospermopsincylindrospermopsin results in decreased expression of BID mRNA23726867
C093628cyproconazolecyproconazole results in decreased expression of BID mRNA22334560
D003561Cytarabine[Cytarabine co-treated with TNFSF10 protein] results in increased expression of BID protein12780785
D003609DactinomycinDactinomycin inhibits the reaction [vorinostat results in increased cleavage of BID protein]11535817
D003609DactinomycinDactinomycin inhibits the reaction [sodium arsenite results in increased expression of BID mRNA]16166651
C004315danthrondanthron results in increased expression of BID protein21126053
D003630Daunorubicin[Daunorubicin co-treated with TNFSF10 protein] results in increased expression of BID protein12780785
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of BID mRNA23914054
C014347decitabinedecitabine affects the expression of BID mRNA23300844
C014347decitabine[Valproic Acid co-treated with decitabine] results in increased cleavage of BID protein21771726
C014347decitabinedecitabine results in decreased methylation of BID gene27923600
C014347decitabinedecitabine results in increased expression of BID mRNA27915011
D003847DeoxyglucoseDeoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]23041229
D003847DeoxyglucoseDeoxyglucose results in increased cleavage of and results in increased activity of BID protein23041229
C007262deoxynivalenoldeoxynivalenol results in decreased expression of BID mRNA22269384
C040424destruxin Bdestruxin B results in increased cleavage of BID protein23751424
C040424destruxin Bdestruxin B results in increased expression of BID protein alternative form23751424
D064730Dexrazoxane[Doxorubicin co-treated with Dexrazoxane] results in decreased expression of BID mRNA26873546
C539263di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone"[Copper co-treated with di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone] results in increased cleavage of BID protein"21750178
C042577diallyl trisulfidediallyl trisulfide results in decreased expression of BID protein22578287
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BID mRNA21266533|2576577
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BID mRNA23242528
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BID mRNA21266533
D002945CisplatinAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]17574045
D002945Cisplatin[andrographolide co-treated with Cisplatin] results in increased expression of BID mRNA24563380
D002945CisplatinCisplatin affects the expression of BID mRNA23300844
D002945Cisplatin[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein17574045
D002945Cisplatin[Cisplatin co-treated with fisetin] results in increased cleavage of BID protein21216935
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of BID mRNA27392435
D002945Cisplatin[Cisplatin co-treated with Pemetrexed] results in increased cleavage of BID protein19351772
D002945CisplatinCisplatin inhibits the reaction [CASP8 protein results in increased cleavage of BID protein]19590723
D002945CisplatinCisplatin results in increased activity of BID protein21052098|2152777
D002945CisplatinCisplatin results in increased cleavage of BID protein21750178
D002945CisplatinCisplatin results in increased expression of BID mRNA27392435
D002945Cisplatin[TNFSF10 protein co-treated with Cisplatin] results in increased cleavage of BID protein21252285
D002945CisplatinCisplatin results in increased expression of BID mRNA21151649
D002945Cisplatin[CTNNA1 protein affects the susceptibility to Cisplatin] which results in increased cleavage of BID protein27989596
D002945CisplatinFSCN2 protein inhibits the reaction [[CTNNA1 protein affects the susceptibility to Cisplatin] which results in increased cleavage of BID protein]27989596
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased cleavage of BID protein19545618
D004008Diclofenac"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Diclofenac results in increased activity of BID protein]"18191430
D004008DiclofenacDiclofenac affects the expression of BID mRNA24752500
D004008DiclofenacDiclofenac results in increased activity of BID protein18191430
D004026DieldrinDieldrin affects the expression of BID mRNA22546817
D004052DiethylnitrosamineBID protein affects the susceptibility to Diethylnitrosamine15904428
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BID mRNA"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BID mRNA]"21294050
C019357dioscin[Acetaminophen co-treated with dioscin] results in increased expression of BID protein22939915
D004317Doxorubicin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]20856197
D004317DoxorubicinBCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Doxorubicin]15289866
D004317DoxorubicinBCL2 protein inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]]20856197
D004317DoxorubicinBCL2 protein inhibits the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]]20856197
D004317DoxorubicinBID protein results in increased susceptibility to Doxorubicin15289866
D004317DoxorubicinDoxorubicin affects the cleavage of BID protein15870702
D004317Doxorubicin[Doxorubicin co-treated with Phellinus linteus extract] results in increased cleavage of BID protein16868541
D004317DoxorubicinDoxorubicin results in decreased expression of BID mRNA16705698
D004317DoxorubicinDoxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein20856197
D004317Doxorubicin[Indomethacin results in increased cleavage of BID protein] which results in increased susceptibility to Doxorubicin15812552
D004317DoxorubicinPI103 promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]20856197
D004317Doxorubicin[Doxorubicin co-treated with Dexrazoxane] results in decreased expression of BID mRNA26873546
D004317DoxorubicinDoxorubicin results in increased expression of BID mRNA26873546
D004317DoxorubicinDoxorubicin results in increased expression of BID protein24902966
D004317DoxorubicinDoxorubicin results in increased phosphorylation of BID protein18845810
D004317DoxorubicinHMOX1 protein inhibits the reaction [Doxorubicin results in increased phosphorylation of BID protein]18845810
D004317DoxorubicinQuercetin inhibits the reaction [Doxorubicin results in increased expression of BID protein]24902966
D004365Drugs, Chinese Herbal"[Drugs, Chinese Herbal co-treated with necrostatin-1] results in increased expression of BID protein modified form"23811387
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of BID protein modified form"23811387
D004365Drugs, Chinese Herbal"arsenic trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of BID protein]"28587418
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased cleavage of BID protein"28587418
C022999echinocystic acidechinocystic acid analog results in increased cleavage of and affects the localization of BID protein15863893
C034192ellipticineellipticine results in decreased expression of and results in increased cleavage of BID protein21843585
D004642Emodin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased degradation of BID protein]27032576
D004642EmodinEmodin results in increased degradation of BID protein27032576
D004642EmodinSB 203580 promotes the reaction [Emodin results in increased degradation of BID protein]27032576
C007590emulphogene BC 720emulphogene BC 720 results in increased expression of BID mRNA25398874
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of BID protein23301498
C109476epoxiconazoleepoxiconazole results in decreased expression of BID mRNA22334560
C007628esculetin[arsenic trioxide co-treated with esculetin] results in increased cleavage of BID protein19428345
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased expression of BID protein24316378
C074283estradiol 3-benzoateQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of BID protein]24316378
C456800ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of BID protein15634644
C002994ethylene dimethanesulfonateethylene dimethanesulfonate results in increased expression of BID mRNA22711419
D005047EtoposideCASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]21801448
D005047EtoposideEstradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA]19426747
D005047EtoposideEtoposide results in increased cleavage of BID protein21801448
D005047EtoposideEtoposide results in increased expression of BID mRNA19426747
D005054EugenolEugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA]20434464
D018683Excitatory Amino Acid AgentsExcitatory Amino Acid Agents results in increased cleavage of BID protein21858143
D018683Excitatory Amino Acid AgentsExcitatory Amino Acid Agents results in increased expression of BID mRNA21858143
C017875fisetin[Cisplatin co-treated with fisetin] results in increased cleavage of BID protein21216935
C017875fisetinfisetin affects the expression of BID protein28181380
C017875fisetinfisetin results in increased cleavage of BID protein21216935
D044948FlavonolsFlavonols results in decreased expression of BID protein28235426
C024352fludarabine[fludarabine co-treated with TNFSF10 protein] results in increased expression of BID protein12780785
C024352fludarabine[LAQ824 co-treated with fludarabine] results in increased activity of BID protein18852132
D005472FluorouracilBCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]15289866
D005472FluorouracilBID protein mutant form results in decreased susceptibility to Fluorouracil15095271
D005472FluorouracilBID protein results in increased susceptibility to Fluorouracil15289866
D005472Fluorouracil[Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein15754201
D005472FluorouracilFluorouracil results in decreased expression of BID protein15754201
D005472FluorouracilFluorouracil results in increased cleavage of and results in increased activity of BID protein21474236
D005472FluorouracilIFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein]21474236
D005485FlutamideFlutamide results in increased expression of BID mRNA24136188
D005620Freund's Adjuvant[Urethane co-treated with Freund's Adjuvant] results in increased expression of BID mRNA12400877
D005665FurosemideFurosemide affects the expression of BID mRNA17497460
C002469fusarenon-Xfusarenon-X results in decreased expression of BID mRNA24983900
D005688Galactosamine[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of BID mRNA21401295
D005688Galactosamine"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of BID protein"12907702
C054597garcinolgarcinol results in increased cleavage of BID protein16052481
C056507gemcitabinegemcitabine results in increased cleavage of BID protein14750167
D019833Genistein[Genistein co-treated with TNFSF10 protein] results in increased cleavage of BID protein19497411
D019833GenisteinGenistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]18546268
D019833GenisteinGenistein promotes the reaction [BID protein binds to ESR1 protein]27156127
D019833GenisteinGenistein results in decreased expression of BID mRNA22228119
D019833GenisteinGenistein results in increased cleavage of and results in increased activity of BID protein18546268
D019833GenisteinGenistein results in increased cleavage of BID protein24299158
D005839GentamicinsGentamicins results in increased expression of BID mRNA22061828
C007845gingerolAcetylcysteine inhibits the reaction [gingerol results in decreased expression of BID protein]25034532
C007845gingerolgingerol results in decreased expression of BID protein25034532
D005944GlucosamineGlucosamine results in increased expression of BID protein20803707
C401311GW 7845benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [GW 7845 results in increased cleavage of BID protein]17400580
C401311GW 7845benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [GW 7845 results in increased cleavage of BID protein]17400580
C401311GW 7845GW 7845 results in increased cleavage of BID protein17400580
C401311GW 7845isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [GW 7845 results in increased cleavage of BID protein]17400580
C500810GW8510GW8510 results in increased expression of BID mRNA22242153
D006571Heterocyclic Compounds[Heterocyclic Compounds binds to Thiazoles] which results in decreased expression of BID protein19014919
D006581HexachlorobenzeneHexachlorobenzene results in decreased expression of BID protein21787832
C501367hispanolonehispanolone analog results in increased cleavage of BID protein25930665
C070164homocastasteronehomocastasterone results in decreased expression of BID protein20833159
D017313Fenretinide[Fenretinide co-treated with TNFSF10 protein] results in increased cleavage of BID protein17273769
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of BID mRNA14689451
C051414hydroxygenkwaninhydroxygenkwanin results in increased expression of BID protein24144774
C559745hyperforin dicyclohexylammoniumhyperforin dicyclohexylammonium results in increased expression of BID protein21376709
D000068877Imatinib Mesylate[Imatinib Mesylate co-treated with alvocidib] results in increased activity of BID protein12231544
C428264indioside Dindioside D results in increased cleavage of BID protein18376857
D007213IndomethacinIndomethacin results in increased cleavage of BID protein15812552
D007213Indomethacin[Indomethacin results in increased cleavage of BID protein] which results in increased susceptibility to Doxorubicin15812552
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of BID mRNA25613284
C051890irinotecan[Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein15754201
C051890irinotecanirinotecan results in decreased expression of BID protein15754201
D007530IsofluraneIsoflurane results in decreased expression of BID mRNA16978161
C425644isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketoneisoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]15450950|1616902
C425644isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketoneisoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [GW 7845 results in increased cleavage of BID protein]17400580
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of BID mRNA27392435
D007654KetoconazoleKetoconazole results in increased expression of BID mRNA25808816
C477361LAQ824[LAQ824 co-treated with fludarabine] results in increased activity of BID protein18852132
C008261lead acetatelead acetate affects the expression of BID protein18618274
C045463leflunomideleflunomide results in increased expression of BID mRNA24136188
C440499lipopolysaccharide, Escherichia coli O111 B4"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of BID protein"12907702
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of BID protein19675143
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of BID protein modified form23170834
D008070Lipopolysaccharidesnotoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of BID protein modified form]23170834
D008070Lipopolysaccharides[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of BID mRNA21401295
D008095Lithocholic Acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Lithocholic Acid results in increased cleavage of and results in increased activity of BID protein]19054763
D008095Lithocholic Acid[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein19054763
D008095Lithocholic Acid[[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein] which results in increased activity of CASP9 protein19054763
D008095Lithocholic Acid[[[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein] which results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein19054763
D008095Lithocholic AcidLithocholic Acid results in increased cleavage of BID protein19054763
C000589248LL-202LL-202 results in increased cleavage of BID protein24752227
C016371lonidamine[arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of BID protein21889928
C016371lonidaminelonidamine results in increased activity of BID protein20605902
D008344Maneb[Maneb co-treated with Paraquat] results in increased expression of BID protein18266926
D008344ManebManeb results in increased expression of BID protein18266926
C025340manganese chloridebafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]28378122
C025340manganese chloridebafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]28378122
C025340manganese chlorideCA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein]28378122
C025340manganese chlorideCA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]28378122
C025340manganese chloridemanganese chloride results in increased cleavage of BID protein21704098
C025340manganese chloridemanganese chloride results in increased expression of BID protein28378122
C025340manganese chloridemanganese chloride results in increased expression of BID protein modified form28378122
C025340manganese chloridepepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein]28378122
C025340manganese chloridepepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]28378122
C021053mangostinmangostin results in decreased expression of BID protein24480042
D009637Masoprocol[Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of BID protein17645780
D008550MelatoninMelatonin promotes the reaction [BID protein binds to BAX protein]19552762
D008550MelatoninMelatonin results in increased expression of BID protein19552762
D008694MethamphetamineMethamphetamine results in increased expression of BID mRNA23820845
D008694MethamphetamineMethamphetamine results in increased expression of BID protein modified form23820845
D008694Methamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA"23820845
D008694Methamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form"23820845
D008727MethotrexateMethotrexate results in increased expression of BID protein modified form23406595
D008731MethoxychlorESR1 gene mutant form promotes the reaction [Methoxychlor results in increased expression of BID mRNA]22306526
D008731MethoxychlorMethoxychlor results in increased expression of BID mRNA22306526
C555027methyl 5-chloro-4,5-didehydrojasmonate"methyl 5-chloro-4,5-didehydrojasmonate results in decreased expression of BID protein"20696234
C042405methyl caffeatemethyl caffeate results in increased expression of BID protein26415618
C072239methyl jasmonatemethyl jasmonate metabolite promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]22079975
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of BID mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BID mRNA"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BID protein modified form"23820845
D008769MethylnitronitrosoguanidineEugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA]20434464
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in decreased expression of BID mRNA20434464
D008777MethyltestosteroneMethyltestosterone results in decreased expression of BID mRNA29191790
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Atorvastatin Calcium results in decreased expression of and results in increased cleavage of BID protein]18339080
D015735MifepristoneMifepristone results in increased expression of BID mRNA17584828
D008911MinocyclineMinocycline results in decreased activity of and results in decreased cleavage of BID protein12930891
D008911MinocyclineMinocycline inhibits the reaction [HTT protein mutant form results in increased cleavage of and results in increased activity of BID protein]12930891
D008911Minocycline[Minocycline results in increased expression of BCL2 protein] which binds to BID protein15004018
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of BID mRNA19945496|2088654
D009151Mustard GasMustard Gas results in increased expression of BID mRNA18955075
C455139myrtucommulone Amyrtucommulone A results in decreased expression of BID mRNA26032814
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of BID mRNA"23634900
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of BID mRNA"25554681
D009285Naphthoquinones[Naphthoquinones co-treated with necrostatin-1] results in increased expression of BID protein modified form23811387
D009285NaphthoquinonesNaphthoquinones results in increased expression of BID protein modified form23811387
C507699necrostatin-1"[Drugs, Chinese Herbal co-treated with necrostatin-1] results in increased expression of BID protein modified form"23811387
C507699necrostatin-1[Naphthoquinones co-treated with necrostatin-1] results in increased expression of BID protein modified form23811387
D009532NickelNickel results in increased expression of BID mRNA24768652|2558310
D009532NickelNickel analog results in increased expression of BID protein27257140
C022838nickel chloridenickel chloride affects the expression of BID mRNA22546817
C022838nickel chloridenickel chloride results in increased expression of BID mRNA21843586
C029938nickel sulfatenickel sulfate results in increased expression of BID mRNA16780908
D009544Niflumic AcidDDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of BID protein]21067863
D009544Niflumic Acid[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of BID protein21067863
C042198nimbolidenimbolide results in increased expression of BID mRNA20429769
C012655nimesulidebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of BID protein]19360361
C012655nimesulidenimesulide results in increased cleavage of and results in increased activity of BID protein19360361
D009569Nitric OxideNitric Oxide results in increased cleavage of BID protein15126337
D009589Nitrogen OxidesNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of BID protein]16041517
D009599Nitroprussidecilostazol inhibits the reaction [Nitroprusside results in decreased expression of BID protein modified form]18311796
D009599Nitroprussidecilostazol inhibits the reaction [Nitroprusside results in increased cleavage of and results in increased localization of BID protein]18311796
D009599NitroprussideNitroprusside results in decreased expression of BID protein modified form18311796
D009599NitroprussideNitroprusside results in increased cleavage of and results in increased localization of BID protein18311796
C542681N,N-dimethylphytosphingosine"benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [N,N-dimethylphytosphingosine results in increased cleavage of BID protein]"19481559
C542681N,N-dimethylphytosphingosine"N,N-dimethylphytosphingosine results in increased cleavage of BID protein"19481559
C010615Nonidet P-40Nonidet P-40 results in increased expression of BID mRNA26552463
C072936notoginsenoside R1notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of BID protein modified form]23170834
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of BID mRNA20971185
C464660obeticholic acidobeticholic acid results in decreased expression of BID mRNA27939613
C025589ochratoxin Aochratoxin A results in decreased expression of BID mRNA24755393
C507134ON 01910ON 01910 results in decreased expression of BID protein19198627|2531676
C009618O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate"O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of BID mRNA"21673326
C009618O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate"PON1 protein affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of BID mRNA]"21673326
C016340o,p'-DDT"o,p'-DDT analog results in decreased expression of BID mRNA"22937105
C016340o,p'-DDT"o,p'-DDT results in increased expression of BID mRNA"22937105
D008939MitotaneMitotane analog results in increased expression of BID mRNA23485034
D008939MitotaneMitotane results in increased expression of BID mRNA23485034
D017239PaclitaxelPaclitaxel results in increased cleavage of BID protein18098270
D017239PaclitaxelPaclitaxel results in increased expression of BID protein14749477
D017239Paclitaxel[Tretinoin co-treated with Paclitaxel] results in increased cleavage of BID protein18098270
D017239PaclitaxelPaclitaxel promotes the reaction [BID protein results in increased secretion of CYCS protein]12126962
C000588809paederosidic acidMAPK8 protein affects the reaction [paederosidic acid results in increased expression of BID protein]28185768
C000588809paederosidic acidpaederosidic acid results in increased expression of BID protein28185768
C482884panduratin Apanduratin A results in decreased expression of BID protein16497706
D010269Paraquat[Maneb co-treated with Paraquat] results in increased expression of BID protein18266926
D010269ParaquatParaquat results in decreased expression of BID mRNA18836921
D010269ParaquatParaquat results in increased cleavage of BID protein28414160
D010269ParaquatParaquat results in increased expression of BID mRNA18056701|1826692
D010269ParaquatParaquat results in increased expression of BID protein18266926
C002669parthenolideparthenolide results in increased cleavage of BID protein16024633
D052638Particulate MatterParticulate Matter results in increased expression of BID protein19675143
D052638Particulate MatterParticulate Matter results in increased expression of BID mRNA24216475
D010365PatulinPatulin results in increased expression of BID mRNA21844328
D000068437Pemetrexed[Cisplatin co-treated with Pemetrexed] results in increased cleavage of BID protein19351772
D010396Penicillamineandrographolide promotes the reaction [Penicillamine inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]]20946909
D010396PenicillaminePenicillamine inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]20946909
D010396PenicillaminePenicillamine promotes the reaction [andrographolide inhibits the reaction [Copper Sulfate results in decreased expression of and results in increased cleavage of BID protein]]20946909
D010416PentachlorophenolPentachlorophenol results in increased expression of BID mRNA23892564
D010431PentoxifyllinePentoxifylline promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]20804743
C031375pepstatinpepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein]28378122
C031375pepstatinpepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]28378122
C031375pepstatinpepstatin inhibits the reaction [thallium nitrate analog results in increased cleavage of BID protein]22669516
C526145Phellinus linteus extract[Doxorubicin co-treated with Phellinus linteus extract] results in increased cleavage of BID protein16868541
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased expression of and results in increased cleavage of BID protein16054126
C471183phenoxodiolphenoxodiol results in increased activity of BID protein16388521
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BID mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of BID mRNA26272509
D054735Phosphorothioate OligonucleotidesPhosphorothioate Oligonucleotides results in increased expression of BID protein16498393
C522973PI103BCL2 protein inhibits the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]]20856197
C522973PI103PI103 promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of and results in increased localization of BID protein]20856197
C121565pifithrinpifithrin inhibits the reaction [silybin results in increased cleavage of BID protein]16777994
C006253pirinixic acidpirinixic acid results in decreased expression of BID mRNA18445702
D010936Plant ExtractsPlant Extracts inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein]20971099
D010936Plant ExtractsPlant Extracts results in decreased expression of BID protein26122529
D010936Plant ExtractsPlant Extracts results in increased cleavage of and results in increased activity of BID protein24021570
D010936Plant ExtractsPlant Extracts results in increased cleavage of BID protein17619071|1949741
D010936Plant ExtractsPlant Extracts results in increased expression of BID mRNA23557933
D010936Plant ExtractsPlant Extracts results in increased expression of BID protein24677778
D010936Plant ExtractsPlant Extracts results in increased expression of BID protein alternative form20229524
D010936Plant ExtractsPlant Extracts inhibits the reaction [Acetaminophen results in increased expression of BID protein]20355050
D028321Plant PreparationsPlant Preparations results in increased expression of BID mRNA24973489
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine affects the expression of BID protein24583197
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in decreased expression of BID mRNA24583197
D011070Poly I-CPoly I-C results in decreased expression of BID protein21418039
D059808PolyphenolsPolyphenols results in increased cleavage of and results in increased activity of BID protein24021570
C472086polyphenon Epolyphenon E results in increased cleavage of BID protein23285096
C432807pramanicinpramanicin analog results in increased cleavage of BID protein23441183
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione results in increased cleavage of BID protein"17475222
D011374ProgesteroneProgesterone results in decreased expression of BID mRNA18037150
C045950propiconazolepropiconazole results in decreased expression of BID mRNA22334560
D011441PropylthiouracilPropylthiouracil results in increased expression of BID mRNA24780913
C107773pterostilbenepterostilbene results in increased expression of BID protein modified form20681671
C432165pyrazolanthronepyrazolanthrone promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]16972261
C031280pyrazolepyrazole results in increased expression of BID mRNA17945193
C010423pyrithione zincpyrithione zinc results in increased cleavage of BID protein20151177
D011794Quercetin[arsenic trioxide co-treated with Quercetin] results in increased cleavage of BID protein18359480
D011794QuercetinQuercetin promotes the reaction [TNFSF10 protein results in decreased expression of BID protein]23711929
D011794QuercetinQuercetin promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]17876056
D011794QuercetinQuercetin results in increased cleavage of BID protein21165570|2429915
D011794QuercetinQuercetin results in increased expression of BID mRNA23727915
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BID mRNA]"21294050
D011794QuercetinQuercetin inhibits the reaction [Doxorubicin results in increased expression of BID protein]24902966
D011794QuercetinQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of BID protein]24316378
C523166quercetin 3-O-beta-(2''-galloyl)-rhamnopyranosidequercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein]23711929
C523166quercetin 3-O-beta-(2''-galloyl)-rhamnopyranosidequercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]25845326
D017382Reactive Oxygen Species[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [sanguinarine results in increased cleavage of BID protein]23660334
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BID protein27634759
D017382Reactive Oxygen Species[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein19054763
D017382Reactive Oxygen Species[[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein] which results in increased activity of CASP9 protein19054763
D017382Reactive Oxygen Species[[[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein] which results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein19054763
D012116Resins, Plant"Resins, Plant results in increased expression of BID protein"27268964
C059514resveratrol[resveratrol co-treated with TNFSF10 protein] results in increased cleavage of BID protein20097879
C059514resveratrolresveratrol results in decreased expression of BID protein20717957
C059514resveratrol[resveratrol results in increased activity of CASP8 protein] which results in increased cleavage of BID protein18276737|1942361
C059514resveratrolresveratrol results in increased cleavage of BID protein16617056|1942361
C059514resveratrolresveratrol results in increased expression of BID protein16731767
C059514resveratrolresveratrol results in increased localization of BID protein19561642
C059514resveratrol[TNFSF10 protein co-treated with resveratrol] results in increased cleavage of BID protein18222423
D012402RotenoneCASP2 protein affects the reaction [Rotenone results in increased cleavage of BID protein]21216964
D012402RotenoneRotenone results in increased cleavage of BID protein21216964
C046245rubimaillinBCL2L1 protein inhibits the reaction [rubimaillin results in increased cleavage of BID protein]19716835
C046245rubimaillinbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [rubimaillin results in increased cleavage of BID protein]19716835
C046245rubimaillinrubimaillin results in increased cleavage of BID protein19716835
D012451SafroleSafrole results in increased expression of BID protein21591240
C005705sanguinarine[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [sanguinarine results in increased cleavage of BID protein]23660334
C005705sanguinarinesanguinarine results in increased cleavage of BID protein23660334
C093642SB 203580SB 203580 promotes the reaction [Emodin results in increased degradation of BID protein]27032576
D012643SeleniumSelenium results in increased cleavage of BID protein12432279
D012715Sesame OilSesame Oil results in increased expression of BID mRNA29191790
C025583sesamolsesamol results in decreased expression of BID27270451
D012822Silicon DioxideSilicon Dioxide results in increased expression of BID mRNA23221170
D012834SilverSilver results in increased expression of BID mRNA21611810
C440975silybinbenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [silybin results in increased cleavage of BID protein]16777994
C440975silybinCaffeine inhibits the reaction [silybin results in increased cleavage of BID protein]16777994
C440975silybinpifithrin inhibits the reaction [silybin results in increased cleavage of BID protein]16777994
C440975silybinsilybin affects the localization of BID protein modified form16777994
C440975silybinsilybin results in increased cleavage of BID protein16777994
D020123Sirolimus[7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of BID protein15767555
D020123Sirolimus[Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BID mRNA19922502
D020123Sirolimus[Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BID protein19922502
D020123SirolimusSirolimus results in decreased expression of BID protein18097008
D020123SirolimusSirolimus results in increased expression of BID mRNA19922502
D020123SirolimusSirolimus results in increased expression of BID protein19922502
C017947sodium arsenitesodium arsenite results in increased expression of BID mRNA20886546
C017947sodium arseniteCEP-11004 inhibits the reaction [sodium arsenite results in increased expression of BID mRNA]16166651
C017947sodium arseniteDactinomycin inhibits the reaction [sodium arsenite results in increased expression of BID mRNA]16166651
C017947sodium arsenitesodium arsenite results in increased cleavage of BID protein16166651
C017947sodium arsenitesodium arsenite results in increased expression of BID mRNA16166651
C016104sodium bichromateCAT protein inhibits the reaction [sodium bichromate results in increased cleavage of BID protein]20298709
C016104sodium bichromateMAPK8 protein affects the reaction [sodium bichromate results in increased cleavage of BID protein]21047991
C016104sodium bichromateMAPK9 protein affects the reaction [sodium bichromate results in increased cleavage of BID protein]21047991
C016104sodium bichromatesodium bichromate results in increased cleavage of BID protein20298709|2104799
C016104sodium bichromateTRP53 mutant form inhibits the reaction [sodium bichromate results in increased cleavage of BID protein]20298709
C471405sorafenib[sorafenib co-treated with TNFSF10 protein] promotes the reaction [CASP8 protein modified form results in increased cleavage of BID protein]17909059
C471405sorafenib[sorafenib co-treated with TNFSF10 protein] results in increased cleavage of BID protein17909059
C471405sorafenib[sorafenib co-treated with Vitamin K 1] results in increased cleavage of BID protein20301194
D013141Spiro CompoundsSpiro Compounds analog results in decreased expression of BID protein25320076
C485419spiruchostatin Aspiruchostatin A results in increased activity of BID protein25078973
C529984spiruchostatin Bspiruchostatin B results in increased activity of BID protein25078973
D019311StaurosporineStaurosporine promotes the reaction [BID protein binds to BAX protein]19552762
D019311StaurosporineStaurosporine results in increased expression of BID protein19552762
C061636suillinsuillin results in decreased expression of BID protein19616521
C016766sulforafansulforafan results in increased expression of BID protein26833863
C016766sulforafansulforafan inhibits the reaction [sulforafan results in increased expression of BID protein]21684301
C016766sulforafansulforafan results in increased expression of BID protein21684301
C025462sulindac sulfidesulindac sulfide results in increased cleavage of BID protein12203115
C025462sulindac sulfidesulindac sulfide results in decreased expression of BID protein16886631
D013629Tamoxifen[Tamoxifen co-treated with TNFSF10 protein] results in increased cleavage of BID protein17767197
D013654TaurineTaurine results in decreased expression of BID mRNA16579726
C041348tcdA protein, Clostridium difficile"tcdA protein, Clostridium difficile results in increased cleavage of BID protein"16368960
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of BID mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased cleavage of BID protein15972635
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BID mRNA14718646|1597263
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of BID mRNA22298810
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of BID mRNA25613284
C009438tetrandrinetetrandrine results in decreased expression of BID protein26822499
C042172thallium nitratepepstatin inhibits the reaction [thallium nitrate analog results in increased cleavage of BID protein]22669516
C042172thallium nitratethallium nitrate affects the cleavage of BID protein22669516
C042172thallium nitratethallium nitrate analog results in increased cleavage of BID protein22669516
D019284ThapsigarginThapsigargin results in decreased expression of BID mRNA22378314
D013844Thiazoles[Heterocyclic Compounds binds to Thiazoles] which results in decreased expression of BID protein19014919
C100040thiosulfinic acidsthiosulfinic acids results in increased cleavage of BID protein19446247
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of BID mRNA24096154
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of BID mRNA27255386
D019772TopotecanBID protein affects the susceptibility to Topotecan16217747
D019772TopotecanAPAF1 promotes the reaction [Topotecan results in increased cleavage of BID protein]19812371
D019772Topotecanbenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Topotecan results in increased cleavage of BID protein]19812371
D019772TopotecanTopotecan results in increased cleavage of BID protein19812371
D019772TopotecanTRP53 inhibits the reaction [Topotecan results in increased cleavage of BID protein]19812371
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in increased cleavage of BID protein"16005259
D014212Tretinoin[Tretinoin co-treated with Paclitaxel] results in increased cleavage of BID protein18098270
D014212TretinoinTretinoin results in decreased expression of BID mRNA23724009
D014212TretinoinTretinoin results in decreased expression of BID protein16242776
D014222Triamcinolone AcetonideTriamcinolone Acetonide results in increased expression of BID protein15987869
C012589trichostatin Atrichostatin A affects the expression of BID mRNA28542535
C012589trichostatin Atrichostatin A promotes the reaction [CASP9 protein affects the localization of BID protein]12556448
C012589trichostatin Atrichostatin A results in increased expression of BID mRNA24935251
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of BID mRNA19042947
C001899triptolidetriptolide results in increased expression of BID protein26990902
C057693troglitazonetroglitazone results in decreased expression of BID mRNA17569031
D014415TunicamycinTunicamycin results in decreased expression of BID mRNA22378314
C113580U 0126U 0126 promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]16972261
C113580U 0126U 0126 inhibits the reaction [Atorvastatin Calcium results in decreased expression of and results in increased cleavage of BID protein]18339080
D014502Uranyl NitrateUranyl Nitrate affects the expression of BID mRNA26362510
D014520Urethane[Urethane co-treated with Freund's Adjuvant] results in increased expression of BID mRNA12400877
D014635Valproic AcidValproic Acid affects the expression of BID mRNA25979313
D014635Valproic Acid[Valproic Acid co-treated with decitabine] results in increased cleavage of BID protein21771726
D014635Valproic AcidValproic Acid results in decreased expression of BID mRNA23179753|2718838
D014635Valproic AcidValproic Acid results in increased cleavage of BID protein19351772
D014635Valproic AcidValproic Acid results in increased expression of BID mRNA22814014
D001335Vehicle EmissionsVehicle Emissions affects the methylation of BID gene25560391
D001335Vehicle EmissionsVehicle Emissions results in increased expression of BID mRNA24216475
D010837Vitamin K 1[sorafenib co-treated with Vitamin K 1] results in increased cleavage of BID protein20301194
C111237vorinostat[Bortezomib co-treated with vorinostat] results in decreased expression of BID protein12893773
C111237vorinostatCycloheximide inhibits the reaction [vorinostat results in increased cleavage of BID protein]11535817
C111237vorinostatDactinomycin inhibits the reaction [vorinostat results in increased cleavage of BID protein]11535817
C111237vorinostat[Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein15754201
C111237vorinostatTNFSF10 protein promotes the reaction [vorinostat results in increased cleavage of BID protein]17410615
C111237vorinostat[vorinostat co-treated with Bortezomib] results in increased cleavage of BID protein17351739
C111237vorinostat[vorinostat co-treated with TNFSF10 protein] results in increased cleavage of BID protein19643600
C111237vorinostatvorinostat results in increased cleavage of BID protein11535817|1197944
C111237vorinostatvorinostat results in increased expression of BID protein20543569
C111237vorinostatvorinostat results in increased cleavage of BID protein18310471
C000588918ziyuglycoside IIziyuglycoside II results in increased cleavage of BID protein24680927
C088658zoledronic acidzoledronic acid results in increased expression of BID mRNA19036117

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005123death receptor binding-TAS8918887  
GO:0005515protein binding-IPI9463381  12624108  12871587  14963330  15694340  16697956  
17052454  17123957  17289999  17485524  19074266  19074440  
20956295  21036904  21382479  23374347  23604079  23782464  
24814347  25241761  25416956  
GO:0031625ubiquitin protein ligase binding-IEA-  
GO:0046982protein heterodimerization activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001836release of cytochrome c from mitochondria-IDA17052454  
GO:0006626protein targeting to mitochondrion-IEA-  
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process-IEA-  
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors-TAS9727491  
GO:0008637apoptotic mitochondrial changes-TAS9727492  
GO:0010918positive regulation of mitochondrial membrane potential-IEA-  
GO:0032461positive regulation of protein oligomerization-IDA19074440  
GO:0032464positive regulation of protein homooligomerization-IDA21041309  
GO:0042127regulation of cell proliferation-IEA-  
GO:0042770signal transduction in response to DNA damage-TAS18309324  
GO:0042775mitochondrial ATP synthesis coupled electron transport-IEA-  
GO:0042981regulation of apoptotic process-TAS-  
GO:0043065positive regulation of apoptotic process-IMP17289999  21525171  
GO:0043066negative regulation of apoptotic process-TAS-  
GO:0051260protein homooligomerization-IEA-  
GO:0051402neuron apoptotic process-TAS16167175  
GO:0090150establishment of protein localization to membrane-IDA21041309  
GO:0090200positive regulation of release of cytochrome c from mitochondria-IGI21041309  
GO:0090200positive regulation of release of cytochrome c from mitochondria-IMP17289999  21262771  
GO:0097284hepatocyte apoptotic process-IEA-  
GO:0097345mitochondrial outer membrane permeabilization-IEA-  
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-TAS-  
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-TAS-  
GO:1902230negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-IEA-  
GO:2000045regulation of G1/S transition of mitotic cell cycle-IEA-  
GO:2000271positive regulation of fibroblast apoptotic process-IEA-  
GO:2001238positive regulation of extrinsic apoptotic signaling pathway-IMP21459798  
GO:2001244positive regulation of intrinsic apoptotic signaling pathway-IMP21262771  
GO:2001244positive regulation of intrinsic apoptotic signaling pathway-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005739mitochondrion-TAS9727491  
GO:0005741mitochondrial outer membrane-TAS-  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0016020membrane-TAS8918887  
GO:0032592integral component of mitochondrial membrane-IEA-  
KEGG ID KEGG Term
hsa04115p53 signaling pathway
hsa04210Apoptosis
hsa04650Natural killer cell mediated cytotoxicity
hsa05010Alzheimer's disease
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa05200Pathways in cancer
hsa05416Viral myocarditis
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111447Activation of BAD and translocation to mitochondria TAS
R-HSA-111452Activation and oligomerization of BAK proteinTAS
R-HSA-111453BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 membersTAS
R-HSA-114294Activation, translocation and oligomerization of BAXTAS
R-HSA-114452Activation of BH3-only proteinsTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5633008TP53 Regulates Transcription of Cell Death GenesTAS
R-HSA-6803204TP53 Regulates Transcription of Genes Involved in Cytochrome C ReleaseTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-75108Activation, myristolyation of BID and translocation to mitochondriaTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21118735Efficacy and tolerability of first-line triple therapy with levofloxacin and amoxicillin plus esomeprazole or rabeprazole for the eradication of Helicobacter pylori infection and the effect of CYP2C19 genotype: a 1-week, randomized, open-label study in Chinese adults. (2010 Nov)Pan XClin Ther
20385711A pooled analysis of the durability and predictors of treatment response of cilostazol in patients with intermittent claudication. (2010 Jun)Pande RLVasc Med
2241595[Single nocturnal dose of ranitidine in the treatment of duodenal ulcer: results of an open multicenter, comparative trial]. (1990 Jan-Mar)Castro Lde PArq Gastroenterol
20171408Effects of oral cilostazol 100 mg BID on long-term patency after percutaneous transluminal angioplasty in patients with femoropopliteal disease undergoing hemodialysis: a retrospective chart review in Japanese patients. (2010 Jan)Ishii HClin Ther
15970277Induction of apoptosis in the lung tissue from rats exposed to cigarette smoke involves p38/JNK MAPK pathway. (2005 Jun 30)Kuo WHChem Biol Interact
27815511Lorcaserin for Smoking Cessation and Associated Weight Gain: A Randomized 12-Week Clinical Trial. (2017 Aug 1)Shanahan WRNicotine Tob Res
24811751Predictors of lapse and relapse to smoking in successful quitters in a varenicline post hoc analysis in Japanese smokers. (2014 Jun 1)Nakamura MClin Ther
28011247Health Status of Patients with Moderate to Severe COPD after Treatment with Nebulized Arformoterol Tartrate or Placebo for 1 Year. (2017 Jan)Donohue JFClin Ther
25048682Analgesic tolerance to morphine is regulated by PPARgamma. (2014 Dec)de Guglielmo GBr J Pharmacol
11956673Effects of grapefruit juice and smoking on verapamil concentrations in steady state. (2002 Apr)Fuhr UEur J Clin Pharmacol
11309844Inhibition of morphine withdrawal by the NMDA receptor antagonist MK-801 in rat is age-dependent. (2001 Jun 15)Zhu HSynapse
7978099Clinical efficacy of the 5-HT3 antagonist ondansetron in alcohol abuse and dependence. (1994 Aug)Sellers EMAlcohol Clin Exp Res
26801172Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain. (2016 Feb)Kashem MANeurochem Res
24722570Cardiac Fas-dependent and mitochondria-dependent apoptosis after chronic cocaine abuse. (2014 Apr 9)Liou CMInt J Mol Sci
1420036[A case of strongyloidiasis accompanied by duodenal ulcer]. (1992 Sep)Kim SYKisaengchunghak Chapchi
25451347One-year safety and efficacy study of arformoterol tartrate in patients with moderate to severe COPD. (2014 Dec)Donohue JFChest
6370542A clinical and pharmacokinetic basis for the selection and use of slow release theophylline products. (1984 Mar-Apr)Hendeles LClin Pharmacokinet
17692720Efficacy and tolerability of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, in a 12-week, randomized, placebo-controlled, dose-response study with 40-week follow-up for smoking cessation in Japanese smokers. (2007 Jun)Nakamura MClin Ther
25304102Application of systematic coronary risk evaluation chart to identify chronic myeloid leukemia patients at risk of cardiovascular diseases during nilotinib treatment. (2015 Mar)Breccia MAnn Hematol
24720376Cigarette smoking during an N-acetylcysteine-assisted cannabis cessation trial in adolescents. (2014 Jul)McClure EAAm J Drug Alcohol Abuse
19232339Nicotine sensitization of monkey striatal dopamine release. (2009 Apr 1)Domino EFEur J Pharmacol
28539935Efficacy and Safety of the Triple Therapy Containing Ilaprazole, Levofloxacin, and Amoxicillin as First-Line Treatment in Helicobacter pylori Infections. (2017)Ahn HJGastroenterol Res Pract
21409381Non-therapeutic anti-FXa levels are common among medical ward patients treated with enoxaparin. (2011 Nov)Saliba WAnn Hematol
21925806Results of an initial clinical trial of varenicline for the treatment of cocaine dependence. (2012 Feb 1)Plebani JGDrug Alcohol Depend
25030802Effects of quetiapine treatment on cocaine self-administration and behavioral indices of sleep in adult rhesus monkeys. (2015 Jan)Brutcher REPsychopharmacology (Berl)
23695545Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a prospective randomized study. (2013 Sep)Seddik HEur J Clin Pharmacol
18084743Effect of varenicline and bupropion SR on craving, nicotine withdrawal symptoms, and rewarding effects of smoking during a quit attempt. (2008 Apr)West RPsychopharmacology (Berl)
22938035What explains willingness to pay for smoking-cessation treatments - addiction level, quit-rate effectiveness or the opening bid? (2012 Nov 1)Olsen JAAppl Health Econ Health Policy
12065157Suppression of alcohol-cessation-oriented hyper-anxiety by the benzoflavone moiety of Passiflora incarnata Linneaus in mice. (2002 Jul)Dhawan KJ Ethnopharmacol
21266057Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data. (2011 Jan 25)Cox LSTrials
18587620The impact of perceived treatment assignment on smoking cessation outcomes among African-American smokers. (2008 Sep)Thomas JLJ Gen Intern Med
18343263Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-blind, 30-day trial. (2008 Feb)Serebruany VLClin Ther
15662490Impact of duloxetine on quality of life for women with symptoms of urinary incontinence. (2005 Sep-Oct)Kinchen KSInt Urogynecol J Pelvic Floor Dysfunct
20659577Combined treatment with formoterol and tiotropium is more efficacious than treatment with tiotropium alone in patients with chronic obstructive pulmonary disease, regardless of smoking status, inhaled corticosteroid use, baseline severity, or gender. (2011 Feb)Tashkin DPPulm Pharmacol Ther
9918994[Eradication of Helicobacter pylori by triple therapy in ulcerous patients: the role of endoscopy and antibiotic sensitivity]. (1998 Dec)Garrido AEnferm Infecc Microbiol Clin
26467690How Effective Is the Quadruple Concomitant Helicobacter Pylori Eradication Therapy for Obese Patients Undergoing Gastric Bypass Surgery? (2016 Jun)Cerqueira RMObes Surg
9097868High-dose naltrexone and liver function safety. (1997 Winter)Marrazzi MAAm J Addict
14643838Amantadine does not modulate reinforcing, subjective, or cardiovascular effects of cocaine in humans. (2003 Dec)Collins EDPharmacol Biochem Behav
19939587A double-blind, placebo-controlled, randomized clinical trial of oral selegiline hydrochloride for smoking cessation in nicotine-dependent cigarette smokers. (2010 Mar 1)Weinberger AHDrug Alcohol Depend
3898818A comparative trial of ranitidine 300 mg at night with ranitidine 150 mg twice daily in the treatment of duodenal and gastric ulcer. (1985 Sep)Farley AAm J Gastroenterol
18164144Levodopa pharmacotherapy for cocaine dependence: choosing the optimal behavioral therapy platform. (2008 Apr 1)Schmitz JMDrug Alcohol Depend
17692719A randomized, placebo-controlled trial of varenicline, a selective alpha4beta2 nicotinic acetylcholine receptor partial agonist, as a new therapy for smoking cessation in Asian smokers. (2007 Jun)Tsai STClin Ther
28540162Effect of brand and advertising medium on demand for e-cigarettes: Evidence from an experimental auction. (2017 Sep)Rousu MCPrev Med Rep
21733822Lung cancer chemoprevention with celecoxib in former smokers. (2011 Jul)Mao JTCancer Prev Res (Phila)
24863033Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat. (2014 Oct)Ciccocioppo RNeuropsychopharmacology
28416970DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD. (2017)Sundar IKClin Epigenetics
10940543A double-blind, placebo-controlled outpatient trial of pergolide for cocaine dependence. (2000 Aug 1)Malcolm RDrug Alcohol Depend
16341695Immunohistochemical detection of apoptotic proteins, p53/Bax and JNK/FasL cascade, in the lung of rats exposed to cigarette smoke. (2006 Jun)Wu CHArch Toxicol
24975047Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis. (2014 Aug)Xu DJ Cell Mol Med