Gene: SDC2

6383
CD362|HSPG|HSPG1|SYND2
syndecan 2
protein-coding
8q22.1
Ensembl:ENSG00000169439 MIM:142460 Vega:OTTHUMG00000164689 UniprotKB:P34741
NC_000008.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.140e-1 (AD)  1.029e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ARHGEF260.943
S1PR10.923
SOX90.921
TP53BP20.921
FERMT20.919
SLC1A30.913
PON20.91
SLC4A40.907
BMPR1B0.905
STOX10.905

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CACNA1F-0.482
ADTRP-0.463
CALHM1-0.461
THEM5-0.454
AGMAT-0.454
TRABD2A-0.451
ABCC12-0.447
TYRP1-0.446
IL12RB2-0.442
DUSP27-0.437

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00020SargramostimBiotechDrug123774-72-1Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of SDC2 mRNA"21354444
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of SDC2 mRNA"19114083
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of SDC2 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of SDC2 mRNA"21346803
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SDC2 mRNA"23196670
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDC2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SDC2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDC2 mRNA"27188386
C0293704-toluidine4-toluidine results in decreased expression of SDC2 mRNA27638505
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDC2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SDC2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDC2 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of SDC2 mRNA26690555
D000082AcetaminophenAcetaminophen affects the expression of SDC2 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SDC2 mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SDC2 mRNA19770486
D000638AmiodaroneAmiodarone affects the expression of SDC2 mRNA19483382
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SDC2 mRNA16483693
C006632arsenic trioxidearsenic trioxide results in decreased expression of SDC2 mRNA12852829|1572508
D001205Ascorbic AcidAscorbic Acid results in decreased expression of SDC2 mRNA15372504
D001553BenzbromaroneBenzbromarone affects the expression of SDC2 mRNA19483382
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SDC2 mRNA21632981
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SDC2 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SDC2 mRNA22228805
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SDC2 mRNA19619570
D004958EstradiolEstradiol results in increased expression of SDC2 mRNA19167446|1961957
D004958Estradiol[bisphenol A co-treated with Estradiol] results in increased expression of SDC2 mRNA26496021
C095105bexarotenebexarotene results in decreased expression of SDC2 mRNA16648578
C006780bisphenol Abisphenol A affects the expression of SDC2 mRNA25181051
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in increased expression of SDC2 mRNA26496021
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of SDC2 mRNA15336504
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of SDC2 mRNA18804290
D002220CarbamazepineCarbamazepine affects the expression of SDC2 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of SDC2 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of SDC2 mRNA15963342
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of SDC2 mRNA16239168
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of SDC2 mRNA24763279
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of SDC2 mRNA23650126
D002994ClofibrateClofibrate affects the expression of SDC2 mRNA19483382
D002995Clofibric AcidClofibric Acid affects the expression of SDC2 mRNA17602206
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SDC2 mRNA17602206
D003300Copper[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of SDC2 mRNA15467011
D003300CopperCopper results in decreased expression of SDC2 mRNA22465980
D019327Copper SulfateCopper Sulfate results in decreased expression of SDC2 mRNA19549813
D003345CorticosteroneCorticosterone results in decreased expression of SDC2 mRNA15755911
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of SDC2 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of SDC2 mRNA19167446
D016572CyclosporineCyclosporine results in decreased expression of SDC2 mRNA20106945|2556210
D000069439DasatinibDasatinib results in increased expression of SDC2 mRNA20579391
C014347decitabinedecitabine affects the expression of SDC2 mRNA17145863
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SDC2 mRNA16054899
D003907DexamethasoneDexamethasone results in decreased expression of SDC2 mRNA22733784
D002945CisplatinSDC2 protein affects the susceptibility to Cisplatin16217747
D004040Dietary CarbohydratesDietary Carbohydrates results in decreased expression of SDC2 mRNA17490981
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of SDC2 mRNA19850644
D004051Diethylhexyl PhthalatePPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SDC2 mRNA]19850644
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SDC2 mRNA17602206
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of SDC2 mRNA28943392
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of SDC2 mRNA19638242
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of SDC2 mRNA17005392
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of SDC2 mRNA17374397
D004237DiuronDiuron results in decreased expression of SDC2 mRNA25152437
C118739entinostatentinostat results in decreased expression of SDC2 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDC2 mRNA"27188386
D004785Environmental PollutantsEnvironmental Pollutants results in decreased expression of SDC2 mRNA24534155
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SDC2 protein23301498
D000431EthanolEthanol results in increased expression of SDC2 mRNA24355176
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of SDC2 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of SDC2 mRNA17557909
D005001EthionineEthionine affects the expression of SDC2 mRNA19483382
D005054EugenolEugenol results in increased expression of SDC2 mRNA17374397
D005419FlavonoidsFlavonoids results in increased expression of SDC2 mRNA18035473
D005485FlutamideFlutamide results in decreased expression of SDC2 mRNA24136188
C039281furanfuran results in decreased expression of SDC2 mRNA26194646
C546771gardiquimodgardiquimod results in increased expression of SDC2 mRNA28003376
C546771gardiquimodProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of SDC2 mRNA]28003376
D005897GlafenineGlafenine results in decreased expression of SDC2 mRNA24136188
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]17109745
D005944GlucosamineGlucosamine results in decreased expression of SDC2 mRNA17109745
D005944GlucosamineIL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]17109745
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of SDC2 mRNA24763279
D006493HeparinHeparin analog results in decreased expression of SDC2 mRNA26476401
D006534Heptachlor EpoxideHeptachlor Epoxide results in decreased expression of SDC2 mRNA25270620
D017313FenretinideFenretinide results in decreased expression of SDC2 mRNA28973697
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SDC2 mRNA16054899
C410337K 7174K 7174 results in decreased expression of SDC2 mRNA24086573
D001556LindaneLindane results in increased expression of SDC2 mRNA18804290
D019808LosartanLosartan results in decreased expression of SDC2 mRNA15100363
D019808LosartanLosartan results in decreased expression of SDC2 protein15100363
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of SDC2 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of SDC2 mRNA26011545
C008493methylselenic acidmethylselenic acid results in increased expression of SDC2 mRNA18548127
D008942MitoxantroneSDC2 protein affects the susceptibility to Mitoxantrone16217747
C523799MRK 003MRK 003 results in decreased expression of SDC2 mRNA21169257
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SDC2 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SDC2 mRNA"25554681|2562005
C051752nefazodonenefazodone results in decreased expression of SDC2 mRNA24136188
C017557nickel subsulfidenickel subsulfide results in increased expression of SDC2 mRNA21086188
C029938nickel sulfatenickel sulfate results in increased expression of SDC2 mRNA16780908|1737439
C012655nimesulidenimesulide results in decreased expression of SDC2 mRNA24136188
D009569Nitric OxideNitric Oxide deficiency results in increased expression of SDC2 mRNA15878706
D009853OmeprazoleOmeprazole affects the expression of SDC2 mRNA19483382
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of SDC2 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of SDC2 mRNA25729387
D010100OxygenOxygen deficiency results in increased expression of SDC2 mRNA26516004
D010100OxygenOxygen deficiency results in increased expression of SDC2 mRNA18803305
D010100OxygenOxygen deficiency results in increased expression of SDC2 protein18803305
D010100Oxygenphenylmethylpyrazolone inhibits the reaction [SDC2 protein promotes the reaction [Oxygen deficiency results in increased abundance of Reactive Oxygen Species]]18803305
D010100OxygenSDC2 protein promotes the reaction [Oxygen deficiency results in increased abundance of Reactive Oxygen Species]18803305
D010100OxygenSDC2 protein promotes the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CCL2 protein]18803305
D010100OxygenSDC2 protein promotes the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein]18803305
D010100OxygenSDC2 protein promotes the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of IL1B protein]18803305
D010100OxygenSDC2 protein promotes the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of TNF protein]18803305
D017239PaclitaxelPaclitaxel results in increased expression of SDC2 mRNA19682730
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of SDC2 mRNA19162173
D010634PhenobarbitalPhenobarbital affects the expression of SDC2 mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SDC2 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of SDC2 mRNA26272509
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [SDC2 protein promotes the reaction [Oxygen deficiency results in increased abundance of Reactive Oxygen Species]]18803305
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [SDC2 protein results in increased expression of and results in increased secretion of CCL2 protein]18803305
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [SDC2 protein results in increased expression of and results in increased secretion of CXCL12 protein]18803305
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [SDC2 protein results in increased expression of and results in increased secretion of IL1B protein]18803305
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [SDC2 protein results in increased expression of and results in increased secretion of TNF protein]18803305
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SDC2 mRNA19710929
C006253pirinixic acidpirinixic acid results in decreased expression of SDC2 mRNA18445702|2005976
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of SDC2 mRNA]20059764
C006253pirinixic acidpirinixic acid affects the expression of SDC2 mRNA19483382
C006253pirinixic acidpirinixic acid results in decreased expression of SDC2 mRNA19162173
D011192Potassium DichromatePotassium Dichromate results in increased expression of SDC2 mRNA23608068
D011374ProgesteroneProgesterone results in decreased expression of SDC2 mRNA23012394|2301818
D011374ProgesteroneProgesterone affects the expression of SDC2 mRNA17251523
D011374ProgesteroneProgesterone results in decreased expression of SDC2 mRNA20726854
D011441PropylthiouracilPropylthiouracil affects the expression of SDC2 mRNA19483382
D011441PropylthiouracilPropylthiouracil results in increased expression of SDC2 mRNA24780913
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of SDC2 mRNA]28003376
C513428pyrachlostrobinpyrachlostrobin results in increased expression of SDC2 mRNA27029645
D011794QuercetinQuercetin results in decreased expression of SDC2 mRNA21632981
D017382Reactive Oxygen Speciesphenylmethylpyrazolone inhibits the reaction [SDC2 protein promotes the reaction [Oxygen deficiency results in increased abundance of Reactive Oxygen Species]]18803305
D017382Reactive Oxygen SpeciesSDC2 protein promotes the reaction [Oxygen deficiency results in increased abundance of Reactive Oxygen Species]18803305
D017382Reactive Oxygen SpeciesSDC2 protein results in increased abundance of Reactive Oxygen Species18803305
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of SDC2 mRNA19167446
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SDC2 mRNA16054899
D012402RotenoneRotenone results in decreased expression of SDC2 mRNA19013527
C017947sodium arsenitesodium arsenite results in decreased expression of and affects the splicing of SDC2 mRNA25879800
C017947sodium arsenitesodium arsenite results in increased expression of SDC2 mRNA22714537
D012999SomanSoman results in increased expression of SDC2 mRNA19281266
D013739TestosteroneTestosterone affects the expression of SDC2 mRNA20403060
D013739TestosteroneTestosterone results in decreased expression of SDC2 mRNA20403060
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SDC2 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SDC2 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SDC2 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of SDC2 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SDC2 mRNA19770486|2756255
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of SDC2 mRNA28943392
D013853ThioacetamideThioacetamide affects the expression of SDC2 mRNA19483382
C009495titanium dioxidetitanium dioxide results in decreased expression of SDC2 mRNA27760801
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of SDC2 mRNA25729387
D019772TopotecanTopotecan results in increased expression of SDC2 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of SDC2 mRNA"19682533
D014212TretinoinTretinoin results in decreased expression of SDC2 mRNA23724009
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDC2 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of SDC2 mRNA24935251|2627250
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of SDC2 mRNA19042947
D014635Valproic AcidValproic Acid affects the expression of SDC2 mRNA25979313
D014810Vitamin EVitamin E results in increased expression of SDC2 mRNA19244175
C088658zoledronic acidzoledronic acid results in decreased expression of SDC2 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI9660868  11356864  18093920  22660413  
GO:0030165PDZ domain binding-IPI18256285  
GO:0042802identical protein binding-IPI18093920  21988832  
GO ID GO Term Qualifier Evidence PubMed
GO:0001523retinoid metabolic process-TAS-  
GO:0006024glycosaminoglycan biosynthetic process-TAS-  
GO:0006027glycosaminoglycan catabolic process-TAS-  
GO:0008150biological_process-ND-  
GO:0016477cell migration-IBA21873635  
GO:0043687post-translational protein modification-TAS-  
GO:0044267cellular protein metabolic process-TAS-  
GO:0048013ephrin receptor signaling pathway-TAS-  
GO:0048813dendrite morphogenesis-IBA21873635  
GO:0048814regulation of dendrite morphogenesis-ISS-  
GO:0050900leukocyte migration-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0005796Golgi lumen-TAS-  
GO:0005886plasma membrane-TAS-  
GO:0009986cell surface-IBA21873635  
GO:0016021integral component of membrane-IEA-  
GO:0043202lysosomal lumen-TAS-  
GO:0062023collagen-containing extracellular matrix-HDA27068509  
KEGG ID KEGG Term
hsa04512ECM-receptor interaction
hsa04514Cell adhesion molecules (CAMs)
hsa05144Malaria
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-1266738Developmental BiologyTAS
R-HSA-1430728MetabolismTAS
R-HSA-1430728MetabolismIEA
R-HSA-1474244Extracellular matrix organizationIEA
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-162582Signal TransductionTAS
R-HSA-1630316Glycosaminoglycan metabolismTAS
R-HSA-1630316Glycosaminoglycan metabolismIEA
R-HSA-1638091Heparan sulfate/heparin (HS-GAG) metabolismTAS
R-HSA-1638091Heparan sulfate/heparin (HS-GAG) metabolismIEA
R-HSA-1643685DiseaseTAS
R-HSA-1793185Chondroitin sulfate/dermatan sulfate metabolismTAS
R-HSA-196854Metabolism of vitamins and cofactorsTAS
R-HSA-1971475A tetrasaccharide linker sequence is required for GAG synthesisTAS
R-HSA-2022928HS-GAG biosynthesisTAS
R-HSA-2022928HS-GAG biosynthesisIEA
R-HSA-2024096HS-GAG degradationTAS
R-HSA-202733Cell surface interactions at the vascular wallTAS
R-HSA-2187338Visual phototransductionTAS
R-HSA-2682334EPH-Ephrin signalingTAS
R-HSA-3000170Syndecan interactionsIEA
R-HSA-3000170Syndecan interactionsTAS
R-HSA-3000171Non-integrin membrane-ECM interactionsIEA
R-HSA-3000171Non-integrin membrane-ECM interactionsTAS
R-HSA-3560782Diseases associated with glycosaminoglycan metabolismTAS
R-HSA-3560783Defective B4GALT7 causes EDS, progeroid typeTAS
R-HSA-3560801Defective B3GAT3 causes JDSSDHDTAS
R-HSA-3656237Defective EXT2 causes exostoses 2TAS
R-HSA-3656253Defective EXT1 causes exostoses 1, TRPS2 and CHDSTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-3781865Diseases of glycosylationTAS
R-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)TAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-3928662EPHB-mediated forward signalingTAS
R-HSA-418594G alpha (i) signalling eventsTAS
R-HSA-422475Axon guidanceTAS
R-HSA-4420332Defective B3GALT6 causes EDSP2 and SEMDJL1TAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6806667Metabolism of fat-soluble vitaminsTAS
R-HSA-71387Metabolism of carbohydratesTAS
R-HSA-71387Metabolism of carbohydratesIEA
R-HSA-8957275Post-translational protein phosphorylationTAS
R-HSA-975634Retinoid metabolism and transportTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27994470Identification of feature genes for smoking-related lung adenocarcinoma based on gene expression profile data. (2016)Liu YOnco Targets Ther