Gene: CXCL12

6387
IRH|PBSF|SCYB12|SDF1|TLSF|TPAR1
C-X-C motif chemokine ligand 12
protein-coding
10q11.21
Ensembl:ENSG00000107562 MIM:600835 Vega:OTTHUMG00000018054 UniprotKB:P48061
NG_016861.1
PubMed
CD|ND|AD
16   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.184e-1 (AD)  2.056e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OLFML30.702
TNFSF100.691
ATP2A30.69
SEMA3G0.685
ANO10.683
MPEG10.678
PGM50.669
CLEC3B0.661
VANGL10.652
CYSLTR10.648

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TUBA3D-0.33
KIF19-0.318
SLC14A1-0.309
SH2D1B-0.299
MOXD1-0.297
FEZF2-0.286
RBP3-0.276
ANGPTL4-0.274
SDC4-0.262
KLF15-0.26

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB06822TinzaparinSmall Molecule9041-08-1ApprovedTarget
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased expression of CXCL12 mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of CXCL12 mRNA"18281256
C49562614-deoxy-11,12-didehydroandrographolide"14-deoxy-11,12-didehydroandrographolide results in decreased expression of CXCL12 mRNA"22101062
C1185591-bromopropane1-bromopropane results in increased expression of CXCL12 mRNA23384675
C1185591-bromopropaneESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CXCL12 mRNA]23384675
C5188741-propyl-8-(4-sulfophenyl)xanthine1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [[BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of CXCL12 protein]27590504
C5188741-propyl-8-(4-sulfophenyl)xanthine1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [BAY 60-6583 results in increased expression of CXCL12 protein]27590504
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CXCL12 mRNA"25510870
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 mRNA"22549810
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 protein"22549810
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"CXCL12 mRNA affects the susceptibility to 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"22549810
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"fulvestrant inhibits the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 mRNA]"22549810
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"fulvestrant inhibits the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 protein]"22549810
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CXCL12 mRNA"19114083
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CXCL12 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of CXCL12 mRNA"22262711
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CXCL12 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CXCL12 mRNA"25510870
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of CXCL12 mRNA"21346803
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CXCL12 mRNA"25510870
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of CXCL12 mRNA"21346803
C07699627-hydroxycholesterol27-hydroxycholesterol results in increased expression of CXCL12 mRNA17872378
C07699627-hydroxycholesterolfulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CXCL12 mRNA]17872378
C4778983-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL12 protein]25822713
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL12 mRNA"23994337
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane affects the expression of CXCL12 mRNA"25380136
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased expression of CXCL12 mRNA"26435001
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased secretion of CXCL12 protein"26435001
C5830744,4'-hexafluorisopropylidene diphenol"ESR1 mutant form inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of CXCL12 mRNA]"26435001
C5830744,4'-hexafluorisopropylidene diphenol"ESR1 mutant form inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased secretion of CXCL12 protein]"26435001
C5830744,4'-hexafluorisopropylidene diphenol"fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of CXCL12 mRNA]"26435001
C5830744,4'-hexafluorisopropylidene diphenol"fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased secretion of CXCL12 protein]"26435001
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C4777284-fluorobenzoyl-TN-140034-fluorobenzoyl-TN-14003 inhibits the reaction [CXCL12 protein results in increased activity of ESR1 protein]19584281
C4777284-fluorobenzoyl-TN-140034-fluorobenzoyl-TN-14003 inhibits the reaction [CXCL12 protein results in increased activity of ESR2 protein]19584281
C4777284-fluorobenzoyl-TN-140034-fluorobenzoyl-TN-14003 inhibits the reaction [CXCL12 protein results in increased phosphorylation of ESR2 protein]19584281
C4777284-fluorobenzoyl-TN-140034-fluorobenzoyl-TN-14003 inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]19584281
C0293704-toluidine4-toluidine results in decreased expression of CXCL12 mRNA27638505
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C496492abrineabrine results in decreased expression of CXCL12 mRNA22595364
D000082AcetaminophenAcetaminophen affects the expression of CXCL12 mRNA17562736
D000082AcetaminophenAcetaminophen results in decreased expression of CXCL12 mRNA17202762
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CXCL12 protein]26138014
C560978aegeline[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of CXCL12 mRNA28843594
C016601afimoxifeneafimoxifene inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein]20549624
C016601afimoxifeneafimoxifene inhibits the reaction [Estrogens results in increased expression of CXCL12 mRNA]21233418
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CXCL12 mRNA19770486
D000497AlloysAlloys results in decreased expression of CXCL12 mRNA23499988
D013196DihydrotestosteroneDihydrotestosterone results in decreased expression of CXCL12 mRNA15953861
D013196DihydrotestosteroneDihydrotestosterone results in decreased expression of CXCL12 protein15953861
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of CXCL12 mRNA21298039
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of CXCL12 mRNA21298039
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CXCL12 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in decreased expression of CXCL12 mRNA"22863853
D047310ApigeninApigenin results in increased expression of CXCL12 mRNA23384675|2839621
D047310ApigeninESR1 protein inhibits the reaction [Apigenin results in increased expression of CXCL12 mRNA]23384675
C004984apocarotenalapocarotenal results in increased expression of CXCL12 mRNA17034753
C006632arsenic trioxidearsenic trioxide inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 protein]25047463
C006632arsenic trioxidearsenic trioxide inhibits the reaction [CXCL12 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]25047463
C006632arsenic trioxideRELA protein inhibits the reaction [arsenic trioxide inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 protein]]25047463
D001194AsbestosAsbestos results in increased expression of CXCL12 protein25162674
D001280AtrazineAtrazine results in decreased expression of CXCL12 mRNA25929836
D001374AzacitidineAzacitidine results in decreased methylation of CXCL12 promoter19748759
D001374AzacitidineAzacitidine results in increased expression of CXCL12 mRNA19748759
D001374AzacitidineAzacitidine results in increased expression of CXCL12 protein19748759
C518875BAY 60-65831-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [[BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of CXCL12 protein]27590504
C518875BAY 60-65831-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [BAY 60-6583 results in increased expression of CXCL12 protein]27590504
C518875BAY 60-6583[BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of CXCL12 protein27590504
C518875BAY 60-6583BAY 60-6583 results in increased expression of CXCL12 protein27590504
C487081belinostatbelinostat results in decreased expression of CXCL12 mRNA27188386
C487081belinostatbelinostat results in increased expression of CXCL12 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of CXCL12 mRNA22643241
C030935benz(a)anthracenebisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]]22643241
C030935benz(a)anthraceneTetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]22643241
D001554BenzeneBenzene results in increased expression of CXCL12 mRNA15120971|1512265
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased expression of CXCL12 mRNA23994337
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CXCL12 mRNA19770486|2156981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CXCL12 mRNA22228805|2234223
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of CXCL12 mRNA"20382639
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CXCL12 mRNA25566086
D019207beta Carotenebeta Carotene results in increased expression of CXCL12 mRNA17034753
D004958Estradiol4-fluorobenzoyl-TN-14003 inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]19584281
D004958Estradiolafimoxifene inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein]20549624
D004958EstradiolCXCL12 mRNA affects the susceptibility to Estradiol22549810
D004958EstradiolESR1 protein inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]23384675
D004958EstradiolEstradiol affects the expression of CXCL12 mRNA22574217
D004958Estradiol[Estradiol co-treated with EGF protein] results in increased expression of CXCL12 mRNA24758408
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of CXCL12 mRNA20660070
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CXCL12 mRNA19619570
D004958EstradiolEstradiol results in decreased expression of CXCL12 mRNA17984146
D004958EstradiolEstradiol results in increased expression of CXCL12 mRNA15913882|1598612
D004958EstradiolEstradiol results in increased expression of CXCL12 protein22549810|2736815
D004958EstradiolEstradiol results in increased secretion of CXCL12 protein20549624
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]17872378|2254981
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 protein]22549810
D004958Estradiolglyceollin inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]19797619
D004958Estradiolglyphosate promotes the reaction [Estradiol results in decreased expression of CXCL12 mRNA]17984146
D004958EstradiolRaloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]21185374
D004958EstradiolRaloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein]20549624
D004958EstradiolTamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of CXCL12 mRNA]24758408
D004958EstradiolTamoxifen inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]19797619|2475840
D004958Estradiol[Estradiol co-treated with Progesterone] results in increased expression of CXCL12 mRNA18556351
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]]22643241
C006780bisphenol Abisphenol A analog results in increased expression of CXCL12 mRNA23384675
C006780bisphenol Abisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA]22549810
C006780bisphenol Abisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 protein]22549810
C006780bisphenol Abisphenol A results in increased expression of CXCL12 mRNA22549810|2338467
C006780bisphenol Abisphenol A results in increased expression of CXCL12 protein22549810|2736815
C006780bisphenol Abisphenol A results in increased secretion of CXCL12 protein20549624
C006780bisphenol ACXCL12 mRNA affects the susceptibility to bisphenol A22549810
C006780bisphenol AESR1 protein affects the reaction [bisphenol A results in increased expression of CXCL12 mRNA]23384675
C006780bisphenol AESR1 protein inhibits the reaction [bisphenol A analog results in increased expression of CXCL12 mRNA]23384675
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CXCL12 mRNA28628672
C006780bisphenol Abisphenol A results in decreased expression of CXCL12 mRNA25181051
C006794brevianamide Abrevianamide A results in increased expression of CXCL12 mRNA19818335
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL12 mRNA22079614
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CXCL12 mRNA20711499
D019328Buthionine SulfoximineButhionine Sulfoximine results in decreased expression of CXCL12 mRNA15878706
C018475butyraldehydebutyraldehyde results in increased expression of CXCL12 mRNA26079696
D002104CadmiumCadmium promotes the reaction [ESR1 protein binds to CXCL12 promoter]24015267
D002104CadmiumCadmium promotes the reaction [[ESR1 protein binds to JUN protein binds to FOS protein] which binds to CXCL12 promoter]24015267
D002104CadmiumCadmium promotes the reaction [[ESR1 protein binds to JUN protein] which binds to CXCL12 promoter]24015267
D002104CadmiumCadmium promotes the reaction [FOS protein binds to CXCL12 promoter]24015267
D002104CadmiumCadmium promotes the reaction [JUN protein binds to CXCL12 promoter]24015267
D002104CadmiumCadmium results in decreased expression of CXCL12 mRNA21120746
D002104CadmiumCadmium results in increased expression of and results in increased secretion of CXCL12 protein24015267
D002104CadmiumCadmium results in increased expression of CXCL12 mRNA24015267
D002104CadmiumESR1 protein affects the reaction [Cadmium results in increased expression of CXCL12 mRNA]24015267
D002104CadmiumESR1 protein affects the reaction [Cadmium results in increased expression of CXCL12 protein]24015267
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CXCL12 protein]26138014
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CXCL12 mRNA12160620
D019256Cadmium ChlorideCadmium Chloride results in increased secretion of CXCL12 protein26138014
D002110Caffeine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of CXCL12 mRNA28843594
D002118CalciumCXCL12 protein results in increased uptake of Calcium10984371|1187209
D002118Calciumresveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]16212921
C020243calcium phosphatecalcium phosphate results in increased expression of CXCL12 protein14600836
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CXCL12 mRNA17484886
D002251Carbon Tetrachloride[2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCL12 protein12626097
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CXCL12 mRNA24763279
C062876cetrorelixcetrorelix results in decreased expression of CXCL12 mRNA21062912
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of CXCL12 mRNA26272509
D002737ChloropreneChloroprene results in decreased expression of CXCL12 mRNA23125180
D002922CiguatoxinsCiguatoxins affects the expression of CXCL12 mRNA18353800
C019304ciprofibrateciprofibrate results in decreased expression of CXCL12 mRNA12771043
C000488cladosporincladosporin results in increased expression of CXCL12 mRNA19818335
D002995Clofibric AcidClofibric Acid results in decreased expression of CXCL12 mRNA21214675
D002995Clofibric AcidClofibric Acid affects the expression of CXCL12 mRNA17602206
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CXCL12 mRNA17602206
D002996ClomipheneClomiphene results in decreased expression of CXCL12 mRNA26865669
D003035CobaltTNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA]23503329
D003035Cobalt[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA23503329
C018021cobaltous chloridecobaltous chloride results in increased expression of CXCL12 mRNA22652775
C018021cobaltous chloridecobaltous chloride results in increased expression of CXCL12 protein22652775
C018021cobaltous chloride1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [[BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of CXCL12 protein]27590504
C018021cobaltous chloride[BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of CXCL12 protein27590504
C004690coclaurine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of CXCL12 mRNA28843594
C030123coumarincoumarin results in decreased expression of CXCL12 mRNA18480146
D003375Coumestrol[Coumestrol co-treated with ESR1 protein] results in increased expression of CXCL12 mRNA18310284
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of CXCL12 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of CXCL12 mRNA19167446|2338467
D003375CoumestrolESR1 protein inhibits the reaction [Coumestrol results in increased expression of CXCL12 mRNA]23384675
D003375CoumestrolESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CXCL12 mRNA]18310284
D003474CurcuminCurcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA]18660423
D003474CurcuminCurcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]18660423
D003474CurcuminCurcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]18660423
D003520CyclophosphamideCyclophosphamide affects the expression of CXCL12 mRNA12624490
D003520CyclophosphamideCyclophosphamide results in increased expression of CXCL12 mRNA16337237
D003520CyclophosphamideCyclophosphamide results in increased expression of CXCL12 mRNA20032115
D003520CyclophosphamideCyclophosphamide results in increased expression of CXCL12 protein19066630|2003211
D016572CyclosporineCyclosporine results in decreased expression of CXCL12 mRNA27989131
D016572CyclosporineCyclosporine results in decreased expression of CXCL12 mRNA19770486
C093628cyproconazolecyproconazole affects the expression of CXCL12 mRNA22045034
C004742daidzeindaidzein results in increased expression of CXCL12 mRNA23384675|2839621
C004742daidzeinESR1 protein inhibits the reaction [daidzein results in increased expression of CXCL12 mRNA]23384675
D000069439DasatinibDasatinib results in decreased expression of CXCL12 protein17962511
D016047ZalcitabineZalcitabine results in increased expression of CXCL12 mRNA17292584
D003634DDTDDT results in increased expression of CXCL12 mRNA25014179
C014347decitabinedecitabine results in decreased methylation of CXCL12 promoter20562917
C014347decitabinedecitabine results in increased expression of CXCL12 mRNA19289100|2056291
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CXCL12 mRNA28628672
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA16054899
D003907DexamethasoneDexamethasone results in decreased expression of CXCL12 mRNA22733784
D003907DexamethasoneDexamethasone results in increased expression of CXCL12 mRNA21041162
D003907Dexamethasone[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
D003907DexamethasoneTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
D003907DexamethasoneTNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA]23503329
D003907Dexamethasone[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA23503329
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of CXCL12 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of CXCL12 mRNA21266533|2489317
D003994BucladesineBucladesine results in decreased expression of CXCL12 mRNA20711499
D002945CisplatinCisplatin results in decreased expression of CXCL12 mRNA21151649
D004041Dietary FatsHMOX1 protein promotes the reaction [Dietary Fats results in increased expression of CXCL12 mRNA]23390531
D004041Dietary FatsDietary Fats results in increased expression of CXCL12 mRNA18042831|2339053
C058705diethyl malatediethyl malate affects the expression of CXCL12 mRNA24814887
C058705diethyl malateS-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CXCL12 mRNA]24814887
C014476diethyl maleatediethyl maleate results in decreased expression of CXCL12 mRNA21161181
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of CXCL12 mRNA12771043
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CXCL12 mRNA17602206
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CXCL12 mRNA28943392
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of CXCL12 mRNA19041683|1963824
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CXCL12 mRNA26865669
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of CXCL12 mRNA25380136
D004176DipyridamoleDipyridamole results in decreased expression of CXCL12 mRNA20711499
D004237DiuronDiuron metabolite results in increased expression of CXCL12 mRNA24172598
D004237DiuronDiuron results in decreased expression of CXCL12 mRNA21551480|2515243
C118739entinostatentinostat results in increased expression of CXCL12 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
D004785Environmental PollutantsEnvironmental Pollutants results in increased expression of CXCL12 mRNA20064776
D004967Estrogensafimoxifene inhibits the reaction [Estrogens results in increased expression of CXCL12 mRNA]21233418
D004967EstrogensEstrogens results in increased expression of CXCL12 mRNA19797619|2123341
D004967Estrogensglyceollin inhibits the reaction [Estrogens results in increased expression of CXCL12 mRNA]19797619
D004970EstroneEstrone results in increased expression of CXCL12 mRNA26865669
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CXCL12 protein27368154
D004997Ethinyl EstradiolEthinyl Estradiol results in increased secretion of CXCL12 protein20549624
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of CXCL12 mRNA17557909
D008656MestranolMestranol results in increased expression of CXCL12 mRNA26865669
D005047EtoposideEtoposide results in decreased expression of CXCL12 mRNA22363485
D005047EtoposideEtoposide results in decreased expression of CXCL12 protein22363485
D028441F2-IsoprostanesCXCL12 protein inhibits the reaction [APP protein results in increased abundance of F2-Isoprostanes]21704645
D015025ZearalenoneZearalenone results in increased expression of CXCL12 mRNA27757495|2839621
C082360fipronilfipronil results in decreased expression of CXCL12 mRNA23962444
D0150732-Acetylaminofluorene[2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCL12 protein12626097
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CXCL12 mRNA15579440
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CXCL12 protein15579440
D005472FluorouracilFluorouracil affects the expression of CXCL12 mRNA18344199
D005472FluorouracilFluorouracil results in increased expression of CXCL12 mRNA16337237
D005485FlutamideFlutamide results in decreased expression of CXCL12 mRNA24136188
D005620Freund's AdjuvantFreund's Adjuvant results in decreased expression of CXCL12 mRNA21149847
C070081fulvestrant"fulvestrant inhibits the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 mRNA]"22549810
C070081fulvestrant"fulvestrant inhibits the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 protein]"22549810
C070081fulvestrantfulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CXCL12 mRNA]17872378
C070081fulvestrant"fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of CXCL12 mRNA]"26435001
C070081fulvestrant"fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased secretion of CXCL12 protein]"26435001
C070081fulvestrantfulvestrant inhibits the reaction [CXCL12 protein results in increased expression of CXCL12 mRNA]19584281|1958428
C070081fulvestrantfulvestrant inhibits the reaction [CXCL12 protein results in increased expression of EB1 mRNA]19584281
C070081fulvestrantfulvestrant inhibits the reaction [CXCL12 protein results in increased expression of PGR mRNA]19584281
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]17872378|2254981
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 protein]22549810
C070081fulvestrantfulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA]22549810
C070081fulvestrantfulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 protein]22549810
C070081fulvestrantfulvestrant results in decreased expression of CXCL12 mRNA26865669
C056933fumonisin B1fumonisin B1 results in decreased expression of CXCL12 mRNA16221962
C039281furanfuran results in decreased expression of CXCL12 mRNA25539665|2619464
C039281furanfuran results in increased expression of CXCL12 mRNA27387713
C064925gadodiamidegadodiamide results in increased expression of CXCL12 mRNA20959327
D019833Genisteinbisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA]22549810
D019833Genisteinbisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 protein]22549810
D019833GenisteinCXCL12 mRNA affects the susceptibility to Genistein22549810
D019833Genisteinfulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA]22549810
D019833Genisteinfulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 protein]22549810
D019833GenisteinGenistein results in increased expression of CXCL12 mRNA22549810|2686566
D019833GenisteinGenistein results in increased expression of CXCL12 protein22549810
D019833GenisteinGenistein results in increased secretion of CXCL12 protein20549624
D005897GlafenineGlafenine results in decreased expression of CXCL12 mRNA24136188
D005944GlucosamineGlucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]17109745
D005944GlucosamineGlucosamine results in decreased expression of CXCL12 mRNA17109745
D005944GlucosamineIL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]17109745
D005947GlucoseGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]18227068
D005947GlucoseGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 protein]18227068
D005947Glucose[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to CXCL12 promoter]18227068
D005947Glucose[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA18227068
D005947Glucose[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 protein18227068
C017343glyceollinglyceollin inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]19797619
C017343glyceollinglyceollin inhibits the reaction [Estrogens results in increased expression of CXCL12 mRNA]19797619
C017343glyceollin[Tamoxifen co-treated with glyceollin] results in decreased expression of CXCL12 mRNA19797619
C004312glycidolglycidol results in increased expression of CXCL12 mRNA24915197
C010974glyphosateglyphosate promotes the reaction [Estradiol results in decreased expression of CXCL12 mRNA]17984146
C010974glyphosateglyphosate results in decreased expression of CXCL12 mRNA17984146
C010974glyphosateglyphosate results in increased expression of CXCL12 mRNA28711546
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CXCL12 mRNA24763279
C120099GW 1929GW 1929 inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]18158351
C120099GW 1929GW 1929 results in decreased susceptibility to CXCL12 protein18158351
D006493HeparinHeparin analog results in decreased expression of CXCL12 mRNA20201787
D006493HeparinHeparin analog results in decreased expression of CXCL12 protein20201787
D006589HexestrolHexestrol results in increased expression of CXCL12 mRNA26865669
C012348higenamine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of CXCL12 mRNA28843594
D017313FenretinideFenretinide results in decreased expression of CXCL12 mRNA28973697
D017313FenretinideFenretinide results in increased expression of CXCL12 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of CXCL12 mRNA17997286
D006861Hydrogen PeroxideSodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL12 mRNA]17997286
D047348Hydrolyzable Tannins[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of CXCL12 mRNA28843594
C031927hydroquinonehydroquinone results in decreased expression of CXCL12 mRNA22960397
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CXCL12 mRNA28628672
D007213IndomethacinIndomethacin results in decreased expression of CXCL12 mRNA25972201
C051890irinotecanirinotecan analog results in decreased expression of CXCL12 mRNA18927307
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CXCL12 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA16054899
D0150561-Methyl-3-isobutylxanthine[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
D0150561-Methyl-3-isobutylxanthineTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
D0150561-Methyl-3-isobutylxanthineTNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA]23503329
D0150561-Methyl-3-isobutylxanthine[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA23503329
C088327JM 3100JM 3100 inhibits the reaction [CXCL12 protein affects the localization of CXCR4 protein]12220670
C088327JM 3100JM 3100 inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]18660423
C088327JM 3100JM 3100 inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]18660423
C088327JM 3100JM 3100 results in decreased expression of CXCL12 mRNA24157575
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of CXCL12 protein19726579
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [HDAC1 mutant form results in increased expression of CXCL12 mRNA]25606026
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CXCL12 mRNA25606026
C045463leflunomideleflunomide results in decreased expression of CXCL12 mRNA24136188
C533894LG 100815LG 100815 results in decreased expression of CXCL12 mRNA16951191
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL12 mRNA"23090859
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [Rutin results in decreased expression of CXCL12 mRNA]28693884
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CXCL12 mRNA28693884
C083152liquiritigeninliquiritigenin results in increased expression of CXCL12 mRNA28396216
C032881lysophosphatidic acid3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL12 protein]25822713
C032881lysophosphatidic acidlysophosphatidic acid results in increased expression of CXCL12 protein25822713
D008345ManganeseManganese results in decreased expression of CXCL12 mRNA23499988
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]18227068
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin results in increased expression of CXCL12 mRNA18227068
D008558MelphalanMelphalan results in decreased expression of CXCL12 mRNA22363485
D008558MelphalanMelphalan results in decreased expression of CXCL12 protein22363485
D008701MethapyrileneMethapyrilene results in decreased expression of CXCL12 mRNA28935588
D008727MethotrexateMethotrexate results in increased expression of CXCL12 mRNA17400583
D008731MethoxychlorMethoxychlor results in increased expression of CXCL12 protein27368154
D008748Methylcholanthrene[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA23519560
C004925methylmercuric chloridemethylmercuric chloride affects the expression of CXCL12 mRNA20864626
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CXCL12 mRNA19840844
D015735MifepristoneMifepristone results in increased expression of CXCL12 mRNA17584828
C070571ML 7ML 7 inhibits the reaction [CXCL12 protein results in increased phosphorylation of MYL9 protein]11751986
C500085muraglitazarmuraglitazar results in increased expression of CXCL12 mRNA21515302
D009173Mycophenolic AcidMycophenolic Acid results in increased expression of CXCL12 mRNA19818335
D009183MycotoxinsMycotoxins results in increased expression of CXCL12 mRNA19818335
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of CXCL12 mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of CXCL12 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CXCL12 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CXCL12 mRNA"25554681
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate affects the expression of CXCL12 mRNA25380136
C051752nefazodonenefazodone results in decreased expression of CXCL12 mRNA24136188
D009532NickelNickel results in decreased expression of CXCL12 mRNA12540486
D009532NickelTNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA]23503329
D009532Nickel[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA23503329
C022838nickel chloridenickel chloride results in decreased secretion of CXCL12 protein18437699
C012655nimesulidenimesulide results in decreased expression of CXCL12 mRNA24136188
D009569Nitric OxideNitric Oxide deficiency results in decreased expression of CXCL12 mRNA15878706
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCL12 mRNA27935865
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CXCL12 mRNA27935865
C510003nordynordy inhibits the reaction [CXCL12 protein results in increased expression of CXCL8 mRNA]17415525
C510003nordynordy inhibits the reaction [CXCL12 protein results in increased expression of VEGFA mRNA]17415525
C062198octa-2,4,6-trienoic acid"octa-2,4,6-trienoic acid results in decreased expression of CXCL12 mRNA"16951191
D019319Okadaic Acid[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CXCL12 mRNA19840844
C030110oxaliplatinoxaliplatin results in decreased expression of CXCL12 mRNA17762391
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of CXCL12 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of CXCL12 mRNA25729387
D010100OxygenOxygen deficiency results in increased expression of CXCL12 mRNA22711276
D010100OxygenValproic Acid inhibits the reaction [Oxygen deficiency results in increased expression of CXCL12 mRNA]22711276
D010100Oxygenvorinostat inhibits the reaction [Oxygen deficiency results in increased expression of CXCL12 mRNA]22711276
D010100OxygenOxygen deficiency results in increased expression of CXCL12 mRNA22652775|2651600
D010100OxygenOxygen deficiency results in increased expression of CXCL12 protein22652775
D010100OxygenOxygen deficiency results in increased susceptibility to CXCL12 protein17476338
D010100OxygenHMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of CXCL12 mRNA]21048024
D010100OxygenHMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of CXCL12 protein]21048024
D010100Oxygenmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]18227068
D010100OxygenOxygen deficiency results in increased expression of CXCL12 mRNA18227068|2104802
D010100OxygenOxygen deficiency results in increased expression of CXCL12 protein21048024
D010100Oxygen[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA18227068
D010100OxygenOxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein18803305
D010100Oxygenphenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein]18803305
D010100OxygenSDC2 protein promotes the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein]18803305
D010100OxygenGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]18227068
D010100OxygenGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 protein]18227068
D010100Oxygen[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to CXCL12 promoter]18227068
D010100Oxygen[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA18227068
D010100Oxygen[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCL12 protein18227068
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of CXCL12]18227068
D010100OxygenOxygen deficiency results in increased expression of CXCL1218227068
D000073878Palm OilPalm Oil results in increased expression of CXCL12 mRNA18042831
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of CXCL12 mRNA26272509
C016030pantogabpantogab results in decreased expression of CXCL12 mRNA17379144
D052638Particulate MatterParticulate Matter results in increased expression of CXCL12 mRNA21708214
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CXCL12 mRNA"25510870
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of CXCL12 mRNA28511854
D026023PermethrinPermethrin results in increased expression of CXCL12 mRNA19017407
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [CXCL12 protein results in increased phosphorylation of MYL9 protein]11751986
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of CXCL12 mRNA]19482888
D010634PhenobarbitalPhenobarbital affects the expression of CXCL12 mRNA23091169
D010634PhenobarbitalPhenobarbital results in decreased expression of CXCL12 mRNA19482888
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein]18803305
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [SDC2 protein results in increased expression of and results in increased secretion of CXCL12 protein]18803305
C060836pioglitazonepioglitazone inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]18158351
C060836pioglitazonepioglitazone results in decreased susceptibility to CXCL12 protein18158351
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCL12 mRNA27935865
C006253pirinixic acidpirinixic acid results in decreased expression of CXCL12 mRNA16221962|1795077
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of CXCL12 mRNA]17950772
D010936Plant ExtractsPlant Extracts results in decreased expression of CXCL12 mRNA23557933
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the expression of CXCL12 mRNA21334430
D011192Potassium DichromatePotassium Dichromate results in decreased expression of CXCL12 mRNA23608068
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of CXCL12 mRNA20660070
D011374ProgesteroneProgesterone results in decreased expression of CXCL12 mRNA21795739
D011374Progesterone[Estradiol co-treated with Progesterone] results in increased expression of CXCL12 mRNA18556351
D011374ProgesteroneProgesterone results in increased expression of CXCL12 mRNA22238285
D011374ProgesteroneProgesterone results in increased expression of CXCL12 mRNA20726854
C045950propiconazolepropiconazole results in decreased expression of CXCL12 mRNA19363144
C005556propionaldehydepropionaldehyde results in decreased expression of CXCL12 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of CXCL12 mRNA24780913
D054328Proton Pump InhibitorsProton Pump Inhibitors results in decreased expression of CXCL12 mRNA25626140
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of CXCL12 mRNA"21152443
C004532quinonequinone results in increased expression of CXCL12 mRNA22960397
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA19059307
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]21185374
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein]20549624
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in decreased expression of CXCL12 mRNA26865669
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of CXCL12 mRNA19167446
C059514resveratrolresveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]16212921
C059514resveratrolresveratrol inhibits the reaction [CXCL12 protein results in increased secretion of VEGFA protein]25815440
C059514resveratrolresveratrol results in increased expression of CXCL12 mRNA28396216
D015474IsotretinoinIsotretinoin results in increased expression of CXCL12 mRNA20436886
D019438RitonavirRitonavir results in decreased expression of CXCL1226626330
C089730rosiglitazonerosiglitazone inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]18158351
C089730rosiglitazonerosiglitazone results in decreased susceptibility to CXCL12 protein18158351
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA16054899
C089730rosiglitazone[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
C089730rosiglitazoneTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
C089730rosiglitazonerosiglitazone affects the expression of CXCL12 mRNA21515302
C089730rosiglitazonerosiglitazone results in decreased expression of CXCL12 mRNA17713437
D012431RutinLipopolysaccharides inhibits the reaction [Rutin results in decreased expression of CXCL12 mRNA]28693884
D012431RutinRutin results in decreased expression of CXCL12 mRNA28693884
C049705S-1,2-dichlorovinyl-N-acetylcysteine"S-1,2-dichlorovinyl-N-acetylcysteine affects the expression of CXCL12 mRNA"16844155
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in decreased expression of CXCL12 mRNA21427059
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of CXCL12 mRNA"24160326
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of CXCL12"19105532
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CXCL12 mRNA]24814887
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CXCL12 mRNA25895662
D019821SimvastatinSimvastatin results in increased expression of CXCL1219591934
D012906SmokeSmoke results in increased expression of CXCL12 mRNA23693141
C017947sodium arsenitesodium arsenite results in decreased expression of CXCL12 mRNA17879257
C017947sodium arsenitesodium arsenite results in increased expression of CXCL12 mRNA21911445
C016104sodium bichromatesodium bichromate results in decreased expression of CXCL12 mRNA25993096
C016104sodium bichromatesodium bichromate results in increased expression of CXCL12 mRNA22561333
D018038Sodium SeleniteSodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL12 mRNA]17997286
D012999SomanSoman results in decreased expression of CXCL12 mRNA19281266
D053260SootSoot results in increased expression of CXCL12 mRNA22461453|2655175
D013241SterigmatocystinSterigmatocystin results in increased expression of CXCL12 mRNA19818335
D013311Streptozocinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]18227068
D013311Streptozocin[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA18227068
D013311StreptozocinStreptozocin results in decreased expression of CXCL12 mRNA18227068
D013311StreptozocinStreptozocin results in decreased expression of CXCL12 protein18227068
D013629TamoxifenCXCL12 protein promotes the reaction [Tamoxifen promotes the reaction [ESR2 protein binds to CCND1 promoter]]19584281
D013629Tamoxifen[Tamoxifen co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA19059307
D013629Tamoxifen[Tamoxifen co-treated with glyceollin] results in decreased expression of CXCL12 mRNA19797619
D013629TamoxifenTamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of CXCL12 mRNA]24758408
D013629TamoxifenTamoxifen inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]19797619|2475840
D013629TamoxifenTamoxifen results in decreased expression of CXCL12 mRNA19797619
D013629TamoxifenTamoxifen results in decreased methylation of CXCL12 promoter19748759
D013629TamoxifenTamoxifen results in increased expression of CXCL12 mRNA19748759
D013629TamoxifenTamoxifen results in increased expression of CXCL12 protein19748759
D013629TamoxifenTamoxifen results in decreased expression of CXCL12 mRNA25123088
C084178telmisartanPPARG protein promotes the reaction [telmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]]18158351
C084178telmisartantelmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]18158351
C084178telmisartantelmisartan results in decreased susceptibility to CXCL12 protein18158351
C501413tesaglitazartesaglitazar results in increased expression of CXCL12 mRNA21515302
C045037testosterone-3-carboxymethyloxime-bovine serum albumin conjugatetestosterone-3-carboxymethyloxime-bovine serum albumin conjugate results in increased expression of CXCL12 mRNA20189893
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of CXCL12 mRNA25172293
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CXCL12 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CXCL12 mRNA17517823|1961957
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CXCL12 protein17517823
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CXCL12 mRNA17555868
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CXCL12 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of CXCL12 mRNA16214954
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of CXCL12 mRNA16054899
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of CXCL12 mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [EGF protein results in increased expression of CXCL12 mRNA]15667827
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CXCL12 mRNA16960034|1879615
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CXCL12 mRNA16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CXCL12 mRNA16267337
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CXCL12 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CXCL12 mRNA21215274
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CXCL12 mRNA16960034
D013752TetracyclineTetracycline results in decreased expression of CXCL12 mRNA24489787
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of CXCL12 mRNA12880637
D013755Tetradecanoylphorbol Acetatebisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]]22643241
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]22643241
D013755Tetradecanoylphorbol Acetate[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA23519560
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CXCL12 mRNA28943392
D013853ThioacetamideThioacetamide results in decreased expression of CXCL12 mRNA23411599
C009495titanium dioxidetitanium dioxide results in increased expression of CXCL12 mRNA19695317
C009495titanium dioxidetitanium dioxide results in increased expression of CXCL12 mRNA23557971
C402696TMC 120ATMC 120A results in increased expression of CXCL12 mRNA19818335
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased methylation of CXCL12 promoter25214829
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of CXCL12 mRNA24096154
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CXCL12 mRNA20133372
D014050TolueneToluene results in increased expression of CXCL12 mRNA22967744
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of CXCL12 mRNA25729387
D019772TopotecanTopotecan results in increased expression of CXCL12 mRNA25729387
D014212Tretinoin[Tretinoin co-treated with CXCL12 protein] results in increased expression of CDKN1A protein17656649
D014212Tretinoin[Tretinoin co-treated with CXCL12 protein] results in increased expression of CEBPB protein17656649
D014212Tretinoin[Tretinoin co-treated with CXCL12 protein] results in increased expression of PTK2B protein17656649
D014212TretinoinTretinoin promotes the reaction [CEBPB protein binds to CXCL12 promoter]17656649
D014212TretinoinTretinoin results in increased expression of CXCL12 mRNA17656649
D014212TretinoinTretinoin results in increased expression of CXCL12 protein17656649
D014212TretinoinTretinoin results in decreased expression of CXCL12 mRNA20488242
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of CXCL12 mRNA19289100|2493525
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of CXCL12 mRNA19042947
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNA15973123
C057693troglitazonetroglitazone results in decreased expression of CXCL12 mRNA21515302
D017973Tungsten CompoundsTungsten Compounds results in decreased expression of CXCL12 mRNA28666766
D014635Valproic AcidValproic Acid inhibits the reaction [Oxygen deficiency results in increased expression of CXCL12 mRNA]22711276
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of CXCL12 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of CXCL12 mRNA23179753|2519280
D014635Valproic AcidValproic Acid results in increased expression of CXCL12 mRNA24383497|2493525
D014635Valproic AcidValproic Acid results in increased methylation of CXCL12 gene29154799
D014635Valproic AcidValproic Acid results in decreased expression of CXCL12 mRNA19136453|2142705
D014635Valproic AcidValproic Acid results in increased expression of CXCL12 mRNA22045034
D014640VancomycinVancomycin results in increased expression of CXCL12 mRNA18930951
D001335Vehicle EmissionsVehicle Emissions affects the methylation of CXCL12 gene25560391
C025643vinclozolinvinclozolin affects the expression of CXCL12 mRNA19015723
C025643vinclozolinvinclozolin results in increased expression of CXCL12 mRNA22570695
C111237vorinostatvorinostat inhibits the reaction [Oxygen deficiency results in increased expression of CXCL12 mRNA]22711276
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA"27188386
C111237vorinostatvorinostat results in increased expression of CXCL12 mRNA26272509
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CXCL12 mRNA27935865
C108830Y 27632Y 27632 inhibits the reaction [CXCL12 protein results in increased phosphorylation of MYL9 protein]11751986
D015016Yohimbine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of CXCL12 mRNA28843594
D015032ZincTNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA]23503329
D015032Zinc[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA23503329
D015032ZincZinc deficiency results in decreased expression of CXCL12 mRNA20857495
C509592zinc(II) dipicolylaminezinc(II) dipicolylamine analog inhibits the reaction [CXCL12 protein binds to and results in increased activity of CXCR4 protein]16722661
C088658zoledronic acidzoledronic acid results in decreased expression of CXCL12 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005102signaling receptor binding-TAS10358157  10438529  
GO:0005178integrin binding-IDA29301984  
GO:0008009chemokine activity-IBA21873635  
GO:0008009chemokine activity-IDA18308860  
GO:0008009chemokine activity-TAS12782716  
GO:0008083growth factor activity-IEA-  
GO:0042056chemoattractant activity-IBA21873635  
GO:0042379chemokine receptor binding-IMP22457824  
GO:0045236CXCR chemokine receptor binding-IBA21873635  
GO:0045236CXCR chemokine receptor binding-IDA20388803  
GO ID GO Term Qualifier Evidence PubMed
GO:0001666response to hypoxia-IEA-  
GO:0001764neuron migration-IEA-  
GO:0001938positive regulation of endothelial cell proliferation-IEA-  
GO:0006874cellular calcium ion homeostasis-TAS10772939  
GO:0006935chemotaxis-TAS12782716  
GO:0006952defense response-IEA-  
GO:0006955immune response-IEA-  
GO:0007155cell adhesion-TAS10198043  
GO:0007165signal transduction-TAS10491003  
GO:0007186G-protein coupled receptor signaling pathway-TAS-  
GO:0007411axon guidance-IBA21873635  
GO:0007411axon guidance-TAS-  
GO:0008015blood circulation-TAS10772939  
GO:0008064regulation of actin polymerization or depolymerization-TAS10570282  
GO:0008344adult locomotory behavior-IEA-  
GO:0009314response to radiation-IEA-  
GO:0009408response to heat-IEA-  
GO:0009615response to virus-TAS10772939  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0022029telencephalon cell migration-IEA-  
GO:0030335positive regulation of cell migration-IBA21873635  
GO:0031100animal organ regeneration-IEA-  
GO:0033603positive regulation of dopamine secretion-IEA-  
GO:0033622integrin activation-IDA29301984  
GO:0043434response to peptide hormone-IEA-  
GO:0045785positive regulation of cell adhesion-IDA23620790  
GO:0048842positive regulation of axon extension involved in axon guidance-IEA-  
GO:0050918positive chemotaxis-IEA-  
GO:0050930induction of positive chemotaxis-IBA21873635  
GO:0050965detection of temperature stimulus involved in sensory perception of pain-IEA-  
GO:0050966detection of mechanical stimulus involved in sensory perception of pain-IEA-  
GO:0060326cell chemotaxis-IBA21873635  
GO:0060326cell chemotaxis-IDA18308860  
GO:0070098chemokine-mediated signaling pathway-IBA21873635  
GO:0070098chemokine-mediated signaling pathway-IDA20388803  
GO:0090026positive regulation of monocyte chemotaxis-IDA18802065  
GO:0090280positive regulation of calcium ion import-TAS10925302  
GO:1902230negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-IDA20388803  
GO:1903237negative regulation of leukocyte tethering or rolling-IDA18308860  
GO:1990478response to ultrasound-IEA-  
GO:2000406positive regulation of T cell migration-IDA23620790  
GO:2000669negative regulation of dendritic cell apoptotic process-IDA15059845  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005737cytoplasm-IEA-  
GO:0009897external side of plasma membrane-IBA21873635  
GO:0070062extracellular exosome-HDA23533145  
KEGG ID KEGG Term
hsa04060Cytokine-cytokine receptor interaction
hsa04062Chemokine signaling pathway
hsa04360Axon guidance
hsa04670Leukocyte transendothelial migration
hsa04672Intestinal immune network for IgA production
hsa05323Rheumatoid arthritis
Reactome ID Reactome Term Evidence
R-HSA-1236394Signaling by ERBB4TAS
R-HSA-1251985Nuclear signaling by ERBB4TAS
R-HSA-1266738Developmental BiologyTAS
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-373076Class A/1 (Rhodopsin-like receptors)TAS
R-HSA-375276Peptide ligand-binding receptorsTAS
R-HSA-376176Signaling by ROBO receptorsTAS
R-HSA-380108Chemokine receptors bind chemokinesTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-418594G alpha (i) signalling eventsTAS
R-HSA-422475Axon guidanceTAS
R-HSA-500792GPCR ligand bindingTAS
R-HSA-8939211ESR-mediated signalingTAS
R-HSA-9006931Signaling by Nuclear ReceptorsTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS
R-HSA-9018519Estrogen-dependent gene expressionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25060794Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. (2014 Sep)Subramanian SArterioscler Thromb Vasc Biol
28167353Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants. (2017 Mar)Shahid SUAtherosclerosis
22216278Large scale association analysis identifies three susceptibility loci for coronary artery disease. (2011)Saade SPLoS One
20147779The role of chemokine receptor CXCR4 in lung cancer. (2010 Mar 15)Gangadhar TCancer Biol Ther
25214829Effect of cigarette smoke condensate on gene promoter methylation in human lung cells. (2014)Lyn-Cook LTob Induc Dis
25734326Plasma concentrations of BDNF and IGF-1 in abstinent cocaine users with high prevalence of substance use disorders: relationship to psychiatric comorbidity. (2015)Pedraz MPLoS One
24854157Plasma profile of pro-inflammatory cytokines and chemokines in cocaine users under outpatient treatment: influence of cocaine symptom severity and psychiatric co-morbidity. (2015 Jul)Araos PAddict Biol
25249326Body mass index, physical activity, and serum markers of inflammation, immunity, and insulin resistance. (2014 Dec)Kitahara CMCancer Epidemiol Biomarkers Prev
20457658Repetitive nicotine exposure leads to a more malignant and metastasis-prone phenotype of SCLC: a molecular insight into the importance of quitting smoking during treatment. (2010 Aug)Martinez-Garcia EToxicol Sci
25762940Sex differences in psychiatric comorbidity and plasma biomarkers for cocaine addiction in abstinent cocaine-addicted subjects in outpatient settings. (2015)Pedraz MFront Psychiatry
28285568Cigarette Smoking Affects Uterine Receptivity Markers. (2017 Jul)Sahin Ersoy GReprod Sci
24808825CXCL12 chemokine and GABA neurotransmitter systems crosstalk and their putative roles. (2014)Guyon AFront Cell Neurosci
29324662Aryl Hydrocarbon Receptor Antagonists Mitigate the Effects of Dioxin on Critical Cellular Functions in Differentiating Human Osteoblast-Like Cells. (2018 Jan 11)Yun CInt J Mol Sci
24486245Estrogen receptor beta and CXCR4/CXCL12 expression: differences by sex and hormonal status in lung adenocarcinoma. (2014 Feb)Rodriguez-Lara VArch Med Res
25844618IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis. (2015 Jun 1)Roos ABAm J Respir Crit Care Med
23891749Sex and body mass index but not CXCL12 801 G/A polymorphism determine the efficacy of hematopoietic cell mobilization: a study in healthy volunteer donors. (2013 Oct)Lenk JBiol Blood Marrow Transplant