Gene info: ID 6401

Gene: SELE

GENE ID: 6401

Synonyms: CD62E|ELAM|ELAM1|ESEL|LECAM2

Description: selectin E

Gene type: protein-coding

Location: 1q24.2

dbXrefs: Ensembl:ENSG00000007908 MIM:131210 Vega:OTTHUMG00000034851 UniprotKB:P16581

RefSeq: NG_012124.1

Retrived from: PubMed|SNP Mapped

SNPs: 6 ANCO-SNPs

Phenotype: ND|AD

# Publications: 8

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 4.134e-1 (AD) 7.994e-1 (ND)

ANCO-SNPs

SNP ID	Position	Alleles	Trait	Variation Type
rs5353	chr1:169733833 (GRCh38.p7)	T>C	alcohol dependence	SNV(Single Nucleotide Variation)
rs932307	chr1:169733564 (GRCh38.p7)	G>A	alcohol dependence	SNV(Single Nucleotide Variation)
rs3917419	chr1:169730678 (GRCh38.p7)	G>A	alcohol dependence	SNV(Single Nucleotide Variation)
rs1076637	chr1:169728303 (GRCh38.p7)	C>T	alcohol dependence	SNV(Single Nucleotide Variation)
rs5359	chr1:169723381 (GRCh38.p7)	T>C	alcohol dependence	SNV(Single Nucleotide Variation)
rs4786	chr1:169722991 (GRCh38.p7)	T>C	alcohol dependence	SNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
CSF3	0.869
CXCL1	0.813
ICAM1	0.742
IL6	0.703
TNFAIP3	0.694
C2CD4B	0.69
RNF122	0.666
NFKB2	0.661
FOSL1	0.66
STX11	0.647

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
AMER3	-0.362
KCNMB2	-0.359
TMEM179	-0.331
GDAP1L1	-0.328
IL34	-0.325
ZMAT4	-0.324
NXPH1	-0.323
CHRM1	-0.322
DLK2	-0.322
KCNK3	-0.321

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB01136	Carvedilol	Small Molecule	72956-09-3	Approved\|Investigational	Target
DB03721	N-acetyl-alpha-neuraminic acid	Small Molecule		Experimental	Target

ID	Drug Name	Action	PubMed
C025205	1,10-phenanthroline	"1,10-phenanthroline affects the reaction [Smoke results in increased expression of SELE protein]"	15560890
C447621	16-(4-fluorophenoxy)lipoxin A4	16-(4-fluorophenoxy)lipoxin A4 inhibits the reaction [IL1B results in increased expression of SELE protein]	15901601
C447621	16-(4-fluorophenoxy)lipoxin A4	16-(4-fluorophenoxy)lipoxin A4 inhibits the reaction [TNF results in increased expression of SELE protein]	15901601
C032668	1-nitropyrene	1-nitropyrene results in increased expression of SELE mRNA	21540303
C400184	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of SELE mRNA	16386258
C400184	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased secretion of SELE protein	16386258
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of SELE mRNA"	27291303
C003585	22-hydroxycholesterol	22-hydroxycholesterol promotes the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	19426978
C003585	22-hydroxycholesterol	22-hydroxycholesterol results in increased expression of SELE mRNA	19426978
C028358	24,25-epoxycholesterol	"24,25-epoxycholesterol promotes the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]"	19426978
C028358	24,25-epoxycholesterol	"24,25-epoxycholesterol results in increased expression of SELE mRNA"	19426978
C076996	27-hydroxycholesterol	27-hydroxycholesterol results in increased expression of SELE mRNA	19426978
C003898	2-anisidine	2-anisidine results in increased expression of SELE mRNA	28089782
C028451	3,4,3',4'-tetrachlorobiphenyl	"3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELE mRNA"	19608276
C028451	3,4,3',4'-tetrachlorobiphenyl	"Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELE mRNA]"	19608276
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELE protein]"	28973532
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SELE protein"	28973532
C005975	3,4-dihydroxyphenylethanol	"3,4-dihydroxyphenylethanol inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]"	12615669
C434003	3-(4-methylphenylsulfonyl)-2-propenenitrile	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]	20580385
C525025	4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol	4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol inhibits the reaction [TNF protein results in increased expression of SELE protein]	17065523
C434605	5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate	"5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of SELE mRNA]"	16285992
C434605	5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate	"5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of SELE protein]"	16285992
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]"	20580385
D000082	Acetaminophen	Acetaminophen results in increased expression of SELE mRNA	14557383
D000082	Acetaminophen	TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of SELE mRNA]	14557383
C056165	acetovanillone	acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
D000111	Acetylcysteine	Acetylcysteine results in decreased expression of SELE mRNA	16084531
D000111	Acetylcysteine	"Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein]]"	19642688
D000117	Acetylglucosamine	[Acetylglucosamine analog binds to Biotin] which binds to SELE protein	12191509
D000117	Acetylglucosamine	Acetylglucosamine analog binds to SELE protein	12191509
C016957	adenosine-3',5'-cyclic phosphorothioate	"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	8780174
C016957	adenosine-3',5'-cyclic phosphorothioate	"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]"	8780174
C016957	adenosine-3',5'-cyclic phosphorothioate	"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]"	8780174
C016957	adenosine-3',5'-cyclic phosphorothioate	"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [TNF protein results in increased expression of SELE protein]"	8780174
C016957	adenosine-3',5'-cyclic phosphorothioate	"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [TNF protein results in increased secretion of SELE mRNA]"	8780174
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of SELE mRNA	22100608
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of SELE protein]	12566129
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	25551565
D024502	alpha-Tocopherol	[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	25551565
D000537	Aluminum Oxide	Aluminum Oxide results in increased expression of SELE protein	18456438
D000537	Aluminum Oxide	Aluminum Oxide results in increased expression of SELE mRNA	18456438
D000537	Aluminum Oxide	Aluminum Oxide results in increased expression of SELE protein	18456438
D000584	Amiloride	Amiloride inhibits the reaction [IL1B protein results in increased expression of SELE protein]	12107048
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of SELE mRNA	16483693
D018501	Antirheumatic Agents	Antirheumatic Agents results in decreased expression of SELE mRNA	24449571
D047310	Apigenin	Apigenin inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	15113938
D047310	Apigenin	Apigenin inhibits the reaction [TNF protein results in increased expression of SELE protein]	15113938\|1698781
D001194	Asbestos	Asbestos results in increased expression of SELE mRNA	22398240
D001205	Ascorbic Acid	[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	25551565
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	25551565
D000069059	Atorvastatin Calcium	Atorvastatin Calcium results in increased expression of SELE protein	19171469
C416282	BAY 11-7085	BAY 11-7085 inhibits the reaction [Chenodeoxycholic Acid results in increased expression of SELE mRNA]	16582018
C416282	BAY 11-7085	BAY 11-7085 inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]	16582018
D001507	Beclomethasone	Beclomethasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]	9371735
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of SELE mRNA	22316170
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of SELE mRNA	22300585
C103712	benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane	benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane analog inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
D004958	Estradiol	[Progesterone co-treated with Estradiol] results in increased expression of SELE mRNA	20226447
D001629	Bezafibrate	[Vitamin E co-treated with Bezafibrate] results in decreased expression of SELE protein modified form	14602771
D001710	Biotin	[Acetylglucosamine analog binds to Biotin] which binds to SELE protein	12191509
C070515	bisindolylmaleimide I	bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
C070515	bisindolylmaleimide I	bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
C006780	bisphenol A	bisphenol A results in decreased expression of SELE mRNA	25181051
D019819	Budesonide	Budesonide inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]	9371735
D019819	Budesonide	"Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	15734790
D019328	Buthionine Sulfoximine	[Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	21971136
C018475	butyraldehyde	butyraldehyde results in increased expression of SELE mRNA	26079696
D002104	Cadmium	Cadmium results in decreased expression of SELE mRNA	24376830
C117342	calfactant	"[Nanotubes, Carbon co-treated with calfactant] results in increased expression of SELE mRNA"	23026733
D002211	Capsaicin	Capsaicin results in increased expression of SELE protein	22150557
D002211	Capsaicin	[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELE protein]	22150557
D002211	Capsaicin	Naproxen inhibits the reaction [Capsaicin results in increased expression of SELE protein]	22150557
D002211	Capsaicin	Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELE protein]	22150557
D000068579	Celecoxib	"Celecoxib inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]]"	14762100
D002635	Chenodeoxycholic Acid	BAY 11-7085 inhibits the reaction [Chenodeoxycholic Acid results in increased expression of SELE mRNA]	16582018
D002635	Chenodeoxycholic Acid	Chenodeoxycholic Acid results in increased expression of SELE mRNA	16582018
D002635	Chenodeoxycholic Acid	SB 203580 inhibits the reaction [Chenodeoxycholic Acid results in increased expression of SELE mRNA]	16582018
D002713	Chlorine	Chlorine results in increased expression of SELE mRNA	22533443
D002794	Choline	"3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELE protein]"	28973532
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELE protein	28973532
C043561	chrysin	chrysin inhibits the reaction [TNF protein results in increased expression of SELE protein]	16987811
C012255	clobazam	[clobazam co-treated with Phenytoin] results in increased expression of SELE protein	16376047
C055162	clopidogrel	clopidogrel results in decreased expression of SELE mRNA	19155974
C055162	clopidogrel	clopidogrel results in decreased expression of SELE protein	19155974
C060728	cobalt oxide	cobalt oxide analog results in increased expression of SELE mRNA	25526690
D003078	Colchicine	Colchicine results in increased expression of SELE mRNA	20624997
D005576	Colforsin	"[Colforsin co-treated with Rolipram] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	8780174
D005576	Colforsin	[Colforsin co-treated with Rolipram] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]	8780174
D005576	Colforsin	[Colforsin co-treated with Rolipram] inhibits the reaction [TNF protein results in increased expression of SELE protein]	8780174
D005576	Colforsin	[Colforsin co-treated with Rolipram] inhibits the reaction [TNF protein results in increased secretion of SELE protein]	8780174
D003300	Copper	[neocuproine affects the abundance of Copper] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	12633744
D003300	Copper	[neocuproine affects the abundance of Copper] inhibits the reaction [TNF protein results in increased expression of SELE protein]	12633744
D003300	Copper	[Copper co-treated with Dietary Sucrose] results in increased expression of SELE mRNA	26033743
D003300	Copper	Copper deficiency results in increased expression of SELE mRNA	26033743
D003474	Curcumin	Curcumin affects the expression of SELE protein	17960570
D003474	Curcumin	Curcumin inhibits the reaction [F2 protein results in increased expression of SELE protein]	18565277
D003474	Curcumin	Curcumin inhibits the reaction [TNF protein results in increased expression of SELE protein]	18565277
D003474	Curcumin	Curcumin results in decreased expression of SELE	18462866
C038459	curdlan	curdlan results in increased expression of SELE mRNA	23543010
C114438	cyanidin 3-O-glucoside	cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]	26422990
D016572	Cyclosporine	Cyclosporine results in increased expression of SELE mRNA	21865292
C561627	dabrafenib	dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]	27458080
C561627	dabrafenib	dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE protein]	27458080
C561627	dabrafenib	dabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein]	29042256
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in increased expression of SELE mRNA	23914054
D003676	Deferoxamine	[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	12633744
D003676	Deferoxamine	[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein]	12633744
D003840	Deoxycholic Acid	Deoxycholic Acid results in increased expression of SELE mRNA	16582018
C053562	desflurane	desflurane inhibits the reaction [TNF protein results in increased expression of SELE protein]	15781515
D003907	Dexamethasone	Dexamethasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]	9371735
D003907	Dexamethasone	Dexamethasone inhibits the reaction [TNF protein results in increased expression of SELE protein]	9371735
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in increased expression of SELE mRNA	28962523
D004008	Diclofenac	Diclofenac results in increased expression of SELE mRNA	26934552
D019422	Dietary Sucrose	[Copper co-treated with Dietary Sucrose] results in increased expression of SELE mRNA	26033743
D019422	Dietary Sucrose	Dietary Sucrose results in increased expression of SELE mRNA	26033743
D054659	Diketopiperazines	Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]	27481191
D054659	Diketopiperazines	Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of SELE protein]	27481191
C007488	dinitrobenzenesulfonic acid	ALOX5 protein affects the reaction [dinitrobenzenesulfonic acid results in increased expression of SELE protein]	15821759
C007488	dinitrobenzenesulfonic acid	dinitrobenzenesulfonic acid results in increased expression of SELE protein	15821759
C007488	dinitrobenzenesulfonic acid	zileuton inhibits the reaction [dinitrobenzenesulfonic acid results in increased expression of SELE protein]	15821759
C521792	DMU-212	DMU-212 affects the expression of SELE mRNA	26428916
D004365	Drugs, Chinese Herbal	"Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein]]"	19642688
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein]"	19642688
D004656	Enalapril	Enalapril inhibits the reaction [sodium arsenite results in increased expression of SELE protein]	28973481
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased expression of SELE mRNA	16084531
D004917	Erythromycin	Erythromycin results in increased expression of SELE protein	16297520
D019304	Ethinyl Estradiol-Norgestrel Combination	Ethinyl Estradiol-Norgestrel Combination results in decreased expression of SELE protein	11996209
C004808	farnesyl pyrophosphate	farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]	10946302
D011345	Fenofibrate	"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]"	20580385
D011345	Fenofibrate	Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]	20580385
D005419	Flavonoids	Flavonoids results in decreased expression of SELE mRNA	18035473
D000068298	Fluticasone	Fluticasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]	9371735
D000068298	Fluticasone	Fluticasone inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	9371735
D000068298	Fluticasone	Fluticasone inhibits the reaction [TNF protein results in increased expression of SELE protein]	9371735
D000068298	Fluticasone	Mifepristone inhibits the reaction [Fluticasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]]	9371735
D005620	Freund's Adjuvant	Freund's Adjuvant results in increased expression of SELE mRNA	20846436
C069837	fullerene C60	fullerene C60 results in increased expression of SELE mRNA	19167457
C039281	furan	furan results in increased expression of SELE mRNA	27387713
C037032	galangin	galangin inhibits the reaction [TNF protein results in increased expression of SELE protein]	16987811
C013550	gastrin 17	gastrin 17 results in decreased expression of SELE protein	15623601
C017338	geranylgeraniol	geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]]	16740276
C002963	geranylgeranyl pyrophosphate	geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]	10946302
C045856	ginkgolide B	ginkgolide B inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	26775663
C045856	ginkgolide B	ginkgolide B inhibits the reaction [TNF protein results in increased expression of SELE protein]	26775663
C045856	ginkgolide B	NR1I2 protein affects the reaction [ginkgolide B inhibits the reaction [TNF protein results in increased expression of SELE mRNA]]	26775663
C045856	ginkgolide B	NR1I2 protein affects the reaction [ginkgolide B inhibits the reaction [TNF protein results in increased expression of SELE protein]]	26775663
C112772	ginsenoside M1	ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of SELE protein]	21875580
C425564	ginsenoside Rh1	ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein]	21875580
D005947	Glucose	"5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of SELE mRNA]"	16285992
D005947	Glucose	"5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of SELE protein]"	16285992
D005947	Glucose	bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
D005947	Glucose	bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
D005947	Glucose	Glucose results in increased expression of SELE	22074828
D005947	Glucose	Glucose results in increased expression of SELE mRNA	16285992\|2096027
D005947	Glucose	Glucose results in increased expression of SELE protein	16285992
D005947	Glucose	manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
D005947	Glucose	manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
D005947	Glucose	Mannitol inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
D005947	Glucose	Mannitol inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
D005947	Glucose	Polyphenols inhibits the reaction [Glucose results in increased expression of SELE mRNA]	21682256
D005947	Glucose	resveratrol inhibits the reaction [Glucose results in increased expression of SELE mRNA]	20960276
D005947	Glucose	SIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of SELE mRNA]]	20960276
D005947	Glucose	Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
D005947	Glucose	Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
D005978	Glutathione	[Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	21971136
D006118	Griseofulvin	Griseofulvin inhibits the reaction [TNF protein results in increased expression of SELE protein]	11367519
C473027	GW 3965	GW 3965 inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	19426978
C473027	GW 3965	GW 3965 results in increased expression of SELE mRNA	19426978
C425931	GW 501516	BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of SELE mRNA]]	23737761
C425931	GW 501516	GW 501516 inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	23737761
D017313	Fenretinide	Fenretinide results in increased expression of SELE mRNA	15958647
D006861	Hydrogen Peroxide	alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of SELE protein]	12566129
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased expression of SELE protein	12566129
D007052	Ibuprofen	Ibuprofen inhibits the reaction [TNF protein results in increased expression of SELE protein]	16769766
D007501	Iron	[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	12633744
D007501	Iron	[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein]	12633744
D007545	Isoproterenol	Isoproterenol inhibits the reaction [TNF protein results in increased secretion of SELE mRNA]	8780174
C561695	(+)-JQ1 compound	(+)-JQ1 compound inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	25263595
C006552	kaempferol	kaempferol inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of SELE protein]	18394220
C006552	kaempferol	kaempferol inhibits the reaction [TNF protein results in increased expression of SELE protein]	16987811
C064309	kaempferol 3-O-sophoroside	kaempferol 3-O-sophoroside inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]	22178603
D020910	Ketorolac	Ketorolac results in decreased expression of SELE mRNA	19620882
D007665	Ketotifen	[Ketotifen co-treated with nimesulide] results in decreased expression of SELE protein	12121561
C063769	KT 5926	[KT 5926 results in decreased activity of MYLK protein] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	15526279
C096429	L 709049	L 709049 inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C433788	lipopolysaccharide, E. coli O26-B6	"DDX58 protein affects the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of SELE mRNA]"	27183587
C433788	lipopolysaccharide, E. coli O26-B6	"lipopolysaccharide, E. coli O26-B6 results in increased expression of SELE mRNA"	27183587
C433788	lipopolysaccharide, E. coli O26-B6	"TLR4 protein affects the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of SELE mRNA]"	27183587
C433788	lipopolysaccharide, E. coli O26-B6	"lipopolysaccharide, E. coli O26-B6 results in increased expression of SELE protein"	21664406
C482199	lipopolysaccharide, E coli O55-B5	"lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein"	19642688
C482199	lipopolysaccharide, E coli O55-B5	"Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein]]"	19642688
C482199	lipopolysaccharide, E coli O55-B5	"Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein]"	19642688
C482199	lipopolysaccharide, E coli O55-B5	"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SELE mRNA"	18930950
C440499	lipopolysaccharide, Escherichia coli O111 B4	"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	8780174
C440499	lipopolysaccharide, Escherichia coli O111 B4	"Celecoxib inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]]"	14762100
C440499	lipopolysaccharide, Escherichia coli O111 B4	"[Colforsin co-treated with Rolipram] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	8780174
C440499	lipopolysaccharide, Escherichia coli O111 B4	"DDX58 protein affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	27183587
C440499	lipopolysaccharide, Escherichia coli O111 B4	"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE mRNA"	14762100
C440499	lipopolysaccharide, Escherichia coli O111 B4	"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein"	14762100
C440499	lipopolysaccharide, Escherichia coli O111 B4	"lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	12794122
C440499	lipopolysaccharide, Escherichia coli O111 B4	"lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	12794122
C440499	lipopolysaccharide, Escherichia coli O111 B4	"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA"	12794122\|2629800
C440499	lipopolysaccharide, Escherichia coli O111 B4	"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein"	12794122\|2629800
C440499	lipopolysaccharide, Escherichia coli O111 B4	"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	26298005
C440499	lipopolysaccharide, Escherichia coli O111 B4	"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	26298005
C440499	lipopolysaccharide, Escherichia coli O111 B4	"Nitric Oxide deficiency inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]]"	14762100
C440499	lipopolysaccharide, Escherichia coli O111 B4	"nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE mRNA]"	14762100
C440499	lipopolysaccharide, Escherichia coli O111 B4	"nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]"	14762100
C440499	lipopolysaccharide, Escherichia coli O111 B4	"TLR4 protein affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	27183587
C440499	lipopolysaccharide, Escherichia coli O111 B4	"Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	15734790
C440499	lipopolysaccharide, Escherichia coli O111 B4	"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA"	15734790
C440499	lipopolysaccharide, Escherichia coli O111 B4	"resveratrol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	15734790
D008070	Lipopolysaccharides	22-hydroxycholesterol promotes the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	19426978
D008070	Lipopolysaccharides	"24,25-epoxycholesterol promotes the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]"	19426978
D008070	Lipopolysaccharides	"3,4-dihydroxyphenylethanol inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]"	12615669
D008070	Lipopolysaccharides	DDX58 protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	27183587
D008070	Lipopolysaccharides	DDX58 protein affects the reaction [TLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]]	27183587
D008070	Lipopolysaccharides	GW 3965 inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	19426978
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SELE mRNA	19426978\|2718358
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SELE protein	27454768
D008070	Lipopolysaccharides	MAVS protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	27183587
D008070	Lipopolysaccharides	oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]	12615669
D008070	Lipopolysaccharides	Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	27454768
D008070	Lipopolysaccharides	Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]	27454768
D008070	Lipopolysaccharides	resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]	12615669
D008070	Lipopolysaccharides	TLR4 protein affects the reaction [DDX58 protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]]	27183587
D008070	Lipopolysaccharides	TLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	27183587
D008070	Lipopolysaccharides	TO-901317 inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	19426978
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SELE mRNA	8566054
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SELE protein	21135813
D008070	Lipopolysaccharides	tepoxalin inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	8566054
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of SELE	12224865
D047311	Luteolin	Luteolin inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	15113938
D047311	Luteolin	Luteolin inhibits the reaction [TNF protein results in increased expression of SELE protein]	15113938
C015329	lycopene	[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	25551565
C015329	lycopene	lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]	22429818
C015329	lycopene	lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]	22429818
C015329	lycopene	lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	25551565
C569869	malondialdehyde-low density lipoprotein, human	"KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]]"	29104011
C569869	malondialdehyde-low density lipoprotein, human	"malondialdehyde-low density lipoprotein, human results in increased expression of SELE mRNA"	29104011
C569869	malondialdehyde-low density lipoprotein, human	"malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein"	29104011
C569869	malondialdehyde-low density lipoprotein, human	"Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE mRNA]"	29104011
C569869	malondialdehyde-low density lipoprotein, human	"Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]"	29104011
C097284	manganese(III)-tetrakis(4-benzoic acid)porphyrin	manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
C097284	manganese(III)-tetrakis(4-benzoic acid)porphyrin	manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
C013592	mangiferin	mangiferin results in decreased expression of SELE mRNA	15135318
D008353	Mannitol	Mannitol inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
D008353	Mannitol	Mannitol inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
C037500	mastoparan	mastoparan results in increased expression of SELE mRNA	10769290
D008555	Melitten	Melitten results in increased expression of SELE mRNA	10769290
D008715	Methionine	"3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELE protein]"	28973532
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELE protein	28973532
D008727	Methotrexate	Methotrexate results in decreased expression of SELE protein	15476228
D008779	Methylthiouracil	"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	26298005
D008779	Methylthiouracil	"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	26298005
D008798	Mevalonic Acid	Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]	10946302
C012258	mevastatin	mevastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]	10946302
C012258	mevastatin	mevastatin promotes the reaction [TNF protein results in increased expression of SELE protein]	10946302
D015735	Mifepristone	Mifepristone inhibits the reaction [Fluticasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]]	9371735
C555916	MitoTEMPO	MitoTEMPO inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C070571	ML 7	[ML 7 results in decreased activity of MYLK protein] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	15526279
D009151	Mustard Gas	Mustard Gas results in increased expression of SELE protein	8975870
D009151	Mustard Gas	Mustard Gas results in increased expression of SELE mRNA	18988085
C083079	N-(3-nitratopivaloyl)cysteine ethyl ester	N-(3-nitratopivaloyl)cysteine ethyl ester results in decreased expression of SELE protein	11046123
D037742	Nanotubes, Carbon	"[Nanotubes, Carbon co-treated with calfactant] results in increased expression of SELE mRNA"	23026733
D037742	Nanotubes, Carbon	"Nanotubes, Carbon affects the expression of SELE mRNA"	23845593
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of SELE mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of SELE mRNA"	25554681
D009288	Naproxen	[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELE protein]	22150557
D009288	Naproxen	Naproxen inhibits the reaction [Capsaicin results in increased expression of SELE protein]	22150557
D000068577	Nebivolol	Nebivolol results in decreased expression of SELE mRNA	17310107
C002701	neocuproine	[neocuproine affects the abundance of Copper] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	12633744
C002701	neocuproine	[neocuproine affects the abundance of Copper] inhibits the reaction [TNF protein results in increased expression of SELE protein]	12633744
D009532	Nickel	Nickel results in increased expression of SELE mRNA	25583101
C022838	nickel chloride	nickel chloride results in increased expression of SELE mRNA	17312168
C012655	nimesulide	[Ketotifen co-treated with nimesulide] results in decreased expression of SELE protein	12121561
D009569	Nitric Oxide	"Nitric Oxide deficiency inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]]"	14762100
C102148	nitroaspirin	"Celecoxib inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]]"	14762100
C102148	nitroaspirin	"Nitric Oxide deficiency inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]]"	14762100
C102148	nitroaspirin	"nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE mRNA]"	14762100
C102148	nitroaspirin	"nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]"	14762100
C014707	nitrosobenzylmethylamine	nitrosobenzylmethylamine results in increased expression of SELE mRNA	17616710
C572573	N-nitroso-tris-chloroethylurea	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELE mRNA	27935865
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SELE mRNA"	18845708
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SELE mRNA]"	18845708
C072936	notoginsenoside R1	notoginsenoside R1 results in decreased expression of SELE protein	18176958
C025589	ochratoxin A	ochratoxin A results in increased expression of SELE protein	28710020
D009828	Oleanolic Acid	Oleanolic Acid inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]	22386814
C002769	oleuropein	oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]	12615669
D010047	Ovalbumin	Ovalbumin results in increased expression of SELE mRNA	22484343
D010100	Oxygen	Oxygen deficiency results in increased expression of SELE mRNA	26516004
D010121	Oxytocin	"KLF4 protein promotes the reaction [Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]]"	29104011
D010121	Oxytocin	"Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE mRNA]"	29104011
D010121	Oxytocin	"Oxytocin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SELE protein]"	29104011
D010126	Ozone	[Ozone co-treated with NOTCH3 gene mutant form] affects the expression of SELE mRNA	25658374
D019308	Palmitic Acid	cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]	26422990
D019308	Palmitic Acid	Palmitic Acid results in increased expression of SELE mRNA	26422990
D019308	Palmitic Acid	wedelolactone inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]	26422990
C002669	parthenolide	parthenolide results in decreased expression of SELE mRNA	16921510
D052638	Particulate Matter	[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SELE mRNA	28013216
D052638	Particulate Matter	Particulate Matter results in increased expression of SELE mRNA	21708214\|2363800
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased expression of SELE mRNA	16221955
D010578	Petroleum	Petroleum affects the expression of SELE mRNA	25208076
C005435	phenylmethylpyrazolone	phenylmethylpyrazolone results in decreased expression of SELE mRNA	17064733
C005435	phenylmethylpyrazolone	phenylmethylpyrazolone results in decreased expression of SELE protein	17064733
D010672	Phenytoin	[clobazam co-treated with Phenytoin] results in increased expression of SELE protein	16376047
C060836	pioglitazone	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELE mRNA	27935865
D010972	Platelet Activating Factor	Platelet Activating Factor results in increased expression of SELE mRNA	16386258
D059808	Polyphenols	Polyphenols inhibits the reaction [Glucose results in increased expression of SELE mRNA]	21682256
D011122	Polyphosphates	dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]	27458080
D011122	Polyphosphates	dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE protein]	27458080
D011122	Polyphosphates	Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]	27481191
D011122	Polyphosphates	Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of SELE protein]	27481191
D011122	Polyphosphates	Polyphosphates results in increased expression of SELE mRNA	27458080\|2748119
D011122	Polyphosphates	Polyphosphates results in increased expression of SELE protein	27458080\|2748119
C072212	PR 39	PR 39 inhibits the reaction [TNF protein results in increased expression of SELE protein]	12388057
D011335	Proadifen	Proadifen inhibits the reaction [TNF protein results in increased expression of SELE protein]	12388057
D011341	Probucol	Probucol inhibits the reaction [TNF protein results in increased expression of SELE protein]	16769766
D011374	Progesterone	[Progesterone co-treated with Estradiol] results in increased expression of SELE mRNA	20226447
D011441	Propylthiouracil	Propylthiouracil results in decreased expression of SELE mRNA	24780913
D011794	Quercetin	Quercetin inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of SELE protein]	18394220
D011794	Quercetin	Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	27454768
D011794	Quercetin	Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]	27454768
D011794	Quercetin	Quercetin inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	15113938
D011794	Quercetin	Quercetin inhibits the reaction [TNF protein results in increased expression of SELE protein]	15113938\|1698781
D011794	Quercetin	"Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELE mRNA]"	19608276
C062940	quinupristin-dalfopristin	quinupristin-dalfopristin results in increased expression of SELE protein	16297520
C059514	resveratrol	resveratrol inhibits the reaction [Glucose results in increased expression of SELE mRNA]	20960276
C059514	resveratrol	resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]	12615669
C059514	resveratrol	resveratrol results in decreased expression of SELE mRNA	20878097
C059514	resveratrol	SIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of SELE mRNA]]	20960276
C059514	resveratrol	"resveratrol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"	15734790
D020889	Rolipram	"[Colforsin co-treated with Rolipram] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]"	8780174
D020889	Rolipram	[Colforsin co-treated with Rolipram] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]	8780174
D020889	Rolipram	[Colforsin co-treated with Rolipram] inhibits the reaction [TNF protein results in increased expression of SELE protein]	8780174
D020889	Rolipram	[Colforsin co-treated with Rolipram] inhibits the reaction [TNF protein results in increased secretion of SELE protein]	8780174
C089730	rosiglitazone	rosiglitazone results in decreased expression of SELE protein	16002742
C089730	rosiglitazone	rosiglitazone results in decreased expression of SELE mRNA	17394460
C089730	rosiglitazone	rosiglitazone results in decreased expression of SELE mRNA	17394460
C093642	SB 203580	SB 203580 inhibits the reaction [Chenodeoxycholic Acid results in increased expression of SELE mRNA]	16582018
D020280	Sertraline	Sertraline results in decreased expression of SELE protein	12912814\|1593281
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of SELE mRNA	23806026
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of SELE mRNA	23221170
D019821	Simvastatin	farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]	10946302
D019821	Simvastatin	geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]]	16740276
D019821	Simvastatin	geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]	10946302
D019821	Simvastatin	Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]	10946302
D019821	Simvastatin	Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE mRNA]	10946302
D019821	Simvastatin	Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]	10946302
D019821	Simvastatin	Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]	10946302\|1674027
D019821	Simvastatin	Simvastatin results in decreased expression of SELE protein modified form	14602771
D019821	Simvastatin	Vitamin E inhibits the reaction [Simvastatin results in decreased expression of SELE protein modified form]	14602771
D012906	Smoke	"1,10-phenanthroline affects the reaction [Smoke results in increased expression of SELE protein]"	15560890
D012906	Smoke	SIRT4 protein inhibits the reaction [Smoke analog results in increased expression of SELE mRNA]	24603126
D012906	Smoke	SIRT4 protein inhibits the reaction [Smoke analog results in increased expression of SELE protein]	24603126
D012906	Smoke	Smoke analog results in increased expression of SELE mRNA	24603126
D012906	Smoke	Smoke analog results in increased expression of SELE protein	24603126
D012906	Smoke	Smoke results in decreased nitrosation of SELE protein	21652289
D012906	Smoke	Smoke results in increased expression of SELE protein	15560890
C009277	sodium arsenate	sodium arsenate results in increased expression of SELE mRNA	21795629
C017947	sodium arsenite	Enalapril inhibits the reaction [sodium arsenite results in increased expression of SELE protein]	28973481
C017947	sodium arsenite	ERN1 affects the reaction [sodium arsenite results in increased expression of SELE protein]	28973481
C017947	sodium arsenite	HIF1A affects the reaction [sodium arsenite results in increased expression of SELE protein]	28973481
C017947	sodium arsenite	sodium arsenite results in increased expression of SELE protein	28973481
C017947	sodium arsenite	Valsartan inhibits the reaction [sodium arsenite results in increased expression of SELE protein]	28973481
C017947	sodium arsenite	XBP1 affects the reaction [sodium arsenite results in increased expression of SELE protein]	28973481
D012969	Sodium Fluoride	Sodium Fluoride inhibits the reaction [IL1B protein results in increased expression of SELE protein]	10946302
D018038	Sodium Selenite	Sodium Selenite inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	11888521
D018038	Sodium Selenite	Sodium Selenite inhibits the reaction [TNF protein results in increased expression of SELE protein]	11888521
D053260	Soot	Soot results in increased expression of SELE mRNA	26551751
C115703	SP 5186	SP 5186 results in decreased expression of SELE protein	11046123
D012460	Sulfasalazine	Sulfasalazine results in increased expression of SELE protein	11264155
D018170	Sumatriptan	[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELE protein]	22150557
D018170	Sumatriptan	Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELE protein]	22150557
D016559	Tacrolimus	Tacrolimus results in increased expression of SELE mRNA	21865292
C073135	tepoxalin	tepoxalin inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	8566054
C000591600	tetrachlorobenzoquinone	acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C000591600	tetrachlorobenzoquinone	Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C000591600	tetrachlorobenzoquinone	benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane analog inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C000591600	tetrachlorobenzoquinone	L 709049 inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C000591600	tetrachlorobenzoquinone	MitoTEMPO inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C000591600	tetrachlorobenzoquinone	NLRP3 protein promotes the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	26901245
C000591600	tetrachlorobenzoquinone	tetrachlorobenzoquinone results in increased expression of SELE protein	26901245
D013755	Tetradecanoylphorbol Acetate	"adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]"	8780174
D013755	Tetradecanoylphorbol Acetate	[Colforsin co-treated with Rolipram] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]	8780174
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased expression of SELE protein	8780174
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased expression of SELE protein	16797888
D013804	Thenoyltrifluoroacetone	Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of SELE mRNA]	16285992
D013804	Thenoyltrifluoroacetone	Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of SELE protein]	16285992
C027385	tibolone	tibolone results in decreased expression of SELE protein	17882670
C009495	titanium dioxide	titanium dioxide results in increased expression of SELE mRNA	25526690
C009495	titanium dioxide	titanium dioxide results in increased expression of SELE protein	22352400
C423915	TO-901317	TO-901317 inhibits the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]	19426978
C423915	TO-901317	TO-901317 results in increased expression of SELE mRNA	19426978
C479163	tofacitinib	tofacitinib results in decreased expression of SELE mRNA	22899318
D014212	Tretinoin	Tretinoin results in increased expression of SELE mRNA	23830798
C050414	tripterine	tripterine inhibits the reaction [IL1B protein results in increased expression of SELE protein]	16769766
C050414	tripterine	tripterine inhibits the reaction [TNF protein results in increased expression of SELE mRNA]	16769766
C050414	tripterine	tripterine inhibits the reaction [TNF protein results in increased expression of SELE protein]	16769766
D014315	Triterpenes	Triterpenes inhibits the reaction [TGFBI protein results in increased expression of SELE protein]	27287417\|2788792
C080163	trovafloxacin	[trovafloxacin co-treated with IL1B protein] affects the localization of SELE protein	10822086
C080163	trovafloxacin	[trovafloxacin co-treated with IL1B protein] results in increased expression of SELE mRNA	10822086
C080163	trovafloxacin	trovafloxacin promotes the reaction [IL1B protein results in increased secretion of SELE protein]	10822086
C080163	trovafloxacin	"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SELE mRNA"	18930950
D000068756	Valsartan	Valsartan inhibits the reaction [sodium arsenite results in increased expression of SELE protein]	28973481
D001335	Vehicle Emissions	[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SELE mRNA	28013216
D014747	Vinblastine	Vinblastine results in increased expression of SELE mRNA	20624997
D014750	Vincristine	Vincristine results in increased expression of SELE mRNA	20624997
D014810	Vitamin E	[Vitamin E co-treated with Bezafibrate] results in decreased expression of SELE protein modified form	14602771
D014810	Vitamin E	Vitamin E inhibits the reaction [Simvastatin results in decreased expression of SELE protein modified form]	14602771
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical affects the expression of SELE mRNA"	25208076
C051122	wedelolactone	wedelolactone inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]	26422990
C104536	xanthohumol	xanthohumol inhibits the reaction [TNF protein results in increased expression of SELE protein]	23503627
C063449	zileuton	zileuton inhibits the reaction [dinitrobenzenesulfonic acid results in increased expression of SELE protein]	15821759
D019345	Zinc Acetate	"Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SELE mRNA]"	18845708
D015054	Zymosan	Zymosan analog results in increased expression of SELE protein	16797888

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0004888	transmembrane signaling receptor activity	-	IMP	12960351
GO:0005515	protein binding	-	IPI	18606703
GO:0033691	sialic acid binding	-	IDA	7680663
GO:0043274	phospholipase binding	-	IDA	12960351
GO:0046872	metal ion binding	-	IEA	-
GO:0070492	oligosaccharide binding	-	IDA	7680663

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0002092	positive regulation of receptor internalization	-	IDA	9312078
GO:0002523	leukocyte migration involved in inflammatory response	-	TAS	18029551
GO:0006954	inflammatory response	-	TAS	2466335
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	-	IMP	18029551
GO:0007159	leukocyte cell-cell adhesion	-	IDA	7680663
GO:0007202	activation of phospholipase C activity	-	IMP	12960351
GO:0019722	calcium-mediated signaling	-	TAS	12960351
GO:0030029	actin filament-based process	-	IDA	8609175
GO:0032496	response to lipopolysaccharide	-	TAS	18029551
GO:0034612	response to tumor necrosis factor	-	TAS	18029551
GO:0050727	regulation of inflammatory response	-	TAS	18029551
GO:0050900	leukocyte migration	-	TAS	-
GO:0050901	leukocyte tethering or rolling	-	IMP	18029551
GO:0070555	response to interleukin-1	-	IDA	8609175

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005615	extracellular space	-	IDA	9290466
GO:0005886	plasma membrane	-	TAS	-
GO:0005887	integral component of plasma membrane	-	IDA	28011641
GO:0005901	caveola	-	IDA	12960351
GO:0005905	clathrin-coated pit	-	IDA	18029551
GO:0030863	cortical cytoskeleton	-	IDA	8609175
GO:0045121	membrane raft	-	IDA	18029551
GO:0048471	perinuclear region of cytoplasm	-	IDA	12960351

KEGG ID	KEGG Term
hsa04514	Cell adhesion molecules (CAMs)
hsa05143	African trypanosomiasis
hsa05144	Malaria

Reactome ID	Reactome Term	Evidence
R-HSA-109582	Hemostasis	TAS
R-HSA-202733	Cell surface interactions at the vascular wall	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
24066042	Polymorphisms in SELE gene and risk of coal workers' pneumoconiosis in Chinese: a case-control study. (2013)	Wang T	PLoS One
11714857	Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. (2001 Nov)	Pallaud C	J Lipid Res
11359462	APOC3, CETP, fibrinogen, and MTHFR are genetic determinants of carotid intima-media thickness in healthy men (the Stanislas cohort). (2001 May)	Pallaud C	Clin Genet
28432984	Cigarette smoke extract counteracts atheroprotective effects of high laminar flow on endothelial function. (2017 Aug)	Giebe S	Redox Biol
26503507	Relationship between gene expression and lung function in Idiopathic Interstitial Pneumonias. (2015 Oct 26)	Steele MP	BMC Genomics
11575217	[APOC3, CETP, beta-fibrinogen and MTHFR are genetic determinants of carotid intim-media thickness (Stanislas cohort)]. (2001 Aug)	Pallaud C	Arch Mal Coeur Vaiss
17036337	Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. (2006 Nov 15)	Carmichael SL	Am J Med Genet A
20970515	Similar gene expression profiles in smokers and patients with moderate COPD. (2011 Feb)	Llinas L	Pulm Pharmacol Ther