Gene: MS4A4E

643680
-
membrane spanning 4-domains A4E
protein-coding
11q12.2
Ensembl:ENSG00000214787 MIM:608401 UniprotKB:Q96PG1
NC_000011.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IL21R0.873
GAPT0.826
TLR100.816
RASGRP40.8
C16orf540.794
HLA-DOA0.79
LILRB20.789
MS4A140.782
MSLN0.782
LILRB30.777

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TM7SF2-0.431
C9orf24-0.429
ASPDH-0.426
BDH1-0.426
CHRNA4-0.425
C1orf53-0.425
FUT9-0.419
CYP46A1-0.414
ACSL6-0.413
WFDC1-0.403

Drugs/Compounds

    There is no DrugBank record for this gene !

    There is no CTD record for this GENE !

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28199971Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. (2017 Apr 11)Lin EOncotarget