Gene: AIDA

64853
C1orf80
axin interactor, dorsalization associated
protein-coding
1q41
Ensembl:ENSG00000186063 MIM:612375 Vega:OTTHUMG00000037653 UniprotKB:Q96BJ3
NC_000001.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.792e-1 (AD)  5.843e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RB10.871
TAB20.869
DCAF120.845
SP30.839
ARHGAP120.831
RAB8B0.831
MOB1A0.829
RAP1B0.825
CD1640.822
PNPLA80.822

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.531
OR4F29-0.505
NUTM2E-0.232
KCNG2-0.232
HES5-0.227
PTGDR2-0.221
ARSF-0.217
KRTAP5-7-0.211
GRHL2-0.201
PRR22-0.187

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in increased expression of AIDA protein26194647
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane affects the expression of AIDA mRNA"18648102
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of AIDA mRNA"25380136
D000082AcetaminophenAcetaminophen results in increased expression of AIDA mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of AIDA mRNA17562736
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of AIDA mRNA24449571
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased methylation of AIDA promoter28329817
C006780bisphenol Abisphenol A affects the expression of AIDA mRNA21786754
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AIDA mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of AIDA mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AIDA mRNA28628672
C018475butyraldehydebutyraldehyde results in decreased expression of AIDA mRNA26079696
C037123cadmium sulfatecadmium sulfate affects the reaction [MTF1 affects the expression of AIDA mRNA]16221973
C100187chloropicrinchloropicrin results in increased expression of AIDA mRNA26352163
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AIDA mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AIDA mRNA28628672
C000944dicrotophosdicrotophos results in decreased expression of AIDA mRNA28302478
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of AIDA mRNA25380136
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of AIDA mRNA22079256
D017313FenretinideFenretinide results in decreased expression of AIDA mRNA28973697
C492448ICG 001ICG 001 results in decreased expression of AIDA mRNA26191083
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AIDA mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AIDA mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AIDA mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AIDA mRNA28628672
D008353MannitolMannitol results in decreased expression of AIDA mRNA25270620
D015741MetriboloneMetribolone results in increased expression of AIDA mRNA17010196
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of AIDA mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of AIDA mRNA"25554681
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of AIDA mRNA25380136
D010416PentachlorophenolPentachlorophenol results in increased expression of AIDA mRNA23892564
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of AIDA mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of AIDA mRNA22079256
D011374ProgesteroneProgesterone results in increased expression of AIDA mRNA23012394|2301818
C010327salinomycinsalinomycin results in decreased expression of AIDA mRNA19682730
D012834SilverSilver results in decreased expression of AIDA mRNA27131904
D018038Sodium SeleniteSodium Selenite results in increased expression of AIDA mRNA18175754
C025643vinclozolinvinclozolin results in increased expression of AIDA mRNA23869203

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  
GO:0019904protein domain specific binding-IEA-  
GO:0035091phosphatidylinositol binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0009953dorsal/ventral pattern formation-ISS-  
GO:0043496regulation of protein homodimerization activity-ISS-  
GO:0043508negative regulation of JUN kinase activity-IDA17681137  
GO:0046329negative regulation of JNK cascade-ISS-  
GO:0048264determination of ventral identity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005575cellular_component-ND-  
GO:0005737cytoplasm-IEA-  
GO:0016020membrane-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29635884Deposition of inhaled nanoparticles is reduced in subjects with COPD and correlates with the extent of emphysema: proof of concept for a novel diagnostic technique. (2018 Apr 10)Aaltonen HLClin Physiol Funct Imaging