Gene: RANBP17

64901
-
RAN binding protein 17
protein-coding
5q35.1
Ensembl:ENSG00000204764 MIM:606141 Vega:OTTHUMG00000163203 UniprotKB:Q9H2T7
NC_000005.10
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.363e-1 (AD)  7.545e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7701805chr5:170942597 (GRCh38.p7)T>A / T>Cnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MTBP0.769
TARBP10.741
ICA1L0.732
CCDC140.727
MTR0.721
MED140.72
ZNF3820.719
DOPEY10.715
ABCA50.715
ZNF7890.708

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CCDC102A-0.394
RHOD-0.358
WDR38-0.353
LHFPL1-0.337
PLA2G5-0.335
MDFI-0.332
FOXJ1-0.33
LYPD1-0.33
PPP1R14B-0.32
DOK1-0.319

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RANBP17 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RANBP17 mRNA"27188386
C006780bisphenol Abisphenol A results in decreased expression of RANBP17 mRNA25181051
C007020chlorophyllin"[chlorophyllin co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RANBP17 mRNA"22485181
D003630DaunorubicinRANBP17 affects the susceptibility to Daunorubicin17545624
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of RANBP17 mRNA27392435
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of RANBP17 mRNA"22485181
D0151279,10-Dimethyl-1,2-benzanthracene"[chlorophyllin co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RANBP17 mRNA"22485181
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of RANBP17 mRNA17942748
C069837fullerene C60fullerene C60 results in decreased expression of RANBP17 mRNA19167457
C039281furanfuran results in decreased expression of RANBP17 mRNA25539665
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of RANBP17 mRNA27392435
C045463leflunomideleflunomide results in increased expression of RANBP17 mRNA28988120
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of RANBP17 mRNA22401849
C028007nickel monoxidenickel monoxide results in decreased expression of RANBP17 mRNA19167457
C006253pirinixic acidpirinixic acid results in increased expression of RANBP17 mRNA20813756
C017947sodium arsenitesodium arsenite results in increased methylation of RANBP17 gene24118411
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RANBP17 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of RANBP17 mRNA24383497|2627250
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of RANBP17 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005049nuclear export signal receptor activity-IBA21873635  
GO:0005525GTP binding-NAS11024021  
GO ID GO Term Qualifier Evidence PubMed
GO:0006606protein import into nucleus-NAS11024021  
GO:0006611protein export from nucleus-IBA21873635  
GO:0051028mRNA transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005643nuclear pore-IBA21873635  
GO:0005643nuclear pore-NAS11024021  
GO:0005737cytoplasm-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal